Bibliografías temáticas / PTGER1

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Literatura académica sobre el tema "PTGER1"

Autor: Grafiati
Publicado: 11 de marzo de 2023
Última modificación: 19 de julio de 2025

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Artículos de revistas sobre el tema "PTGER1"

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Chandras, C., T. E. Harris, A. López Bernal, D. R. E. Abayasekara та A. E. Michael. "PTGER1 and PTGER2 receptors mediate regulation of progesterone synthesis and type 1 11β-hydroxysteroid dehydrogenase activity by prostaglandin E2 in human granulosa–lutein cells". Journal of Endocrinology 194, № 3 (2007): 595–602. http://dx.doi.org/10.1677/joe-07-0128.

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In luteinizing granulosa cells, prostaglandin E2 (PGE2) can exert luteotrophic actions, apparently via the cAMP signalling pathway. In addition to stimulating progesterone synthesis, PGE2 can also stimulate oxidation of the physiological glucocorticoid, cortisol, to its inactive metabolite, cortisone, by the type 1 11β-hydroxysteroid dehydrogenase (11βHSD1) enzyme in human granulosa–lutein cells. Having previously shown these human ovarian cells to express functional G-protein coupled, E-series prostaglandin (PTGER)1, PTGER2 and PTGER4 receptors, the aim of this study was to delineate the role
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Miyoshi, Moe, Masayuki Sato, Kenji Saito, et al. "Maternal Protein Restriction Alters the Renal Ptger1 DNA Methylation State in SHRSP Offspring." Nutrients 10, no. 10 (2018): 1436. http://dx.doi.org/10.3390/nu10101436.

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We previously reported that maternal protein restriction (LP) during pregnancy increases salt sensitivity in offspring using the Stroke-Prone Spontaneously Hypertensive Rat (SHRSP). In the present study, we focus on DNA methylation profiles of prostaglandin E receptor 1 gene (ptger1), which is known to be associated with hypertension. We evaluated the ptger1 DNA methylation status via bisulfite sequencing, and analyzed the expression of ptger1-related genes. The results of these analyses showed that, compared to controls, the LP-S offspring exhibited both marked ptger1 hypermethylation, and si
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González, Luz María, Nicolás Roberto Robles, Sonia Mota-Zamorano, José Manuel Valdivielso, Juan López-Gómez, and Guillermo Gervasini. "Genetic Variants in PGE2 Receptors Modulate the Risk of Nephrosclerosis and Clinical Outcomes in These Patients." Journal of Personalized Medicine 11, no. 8 (2021): 772. http://dx.doi.org/10.3390/jpm11080772.

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Prostaglandin E2 (PGE2) is a major actor mediating renal injury. We aimed to determine genetic variability in the genes coding for its receptors (PTGER1-4) and study associations with nephrosclerosis risk and clinical outcomes. We identified 96 tag-SNPs capturing global variability in PTGER1-4 and screened 1209 nephrosclerosis patients and controls. The effect of these variants was evaluated by multivariate regression analyses. Two PTGER3 SNPs, rs11209730 and rs10399704, remained significant in a backward elimination regression model with other non-genetic variables (OR = 1.45 (1.07–1.95), p =
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Kowalewski, Mariusz Pawel, Hakki Bülent Beceriklisoy, Christiane Pfarrer, et al. "Canine placenta: a source of prepartal prostaglandins during normal and antiprogestin-induced parturition." REPRODUCTION 139, no. 3 (2010): 655–64. http://dx.doi.org/10.1530/rep-09-0140.

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Expression of cyclooxygenase 2 (COX2, now known as PTGS2), prostaglandin E2 synthase (PTGES, PGES), and prostaglandin F2α synthase (PGFS), of the respective receptors PTGFR (FP), PTGER2 (EP2), and PTGER4 (EP4) and of the progesterone receptor (PGR, PR) was assessed by real-time PCR, immunohistochemistry (IHC), or in situ hybridization (ISH) in utero/placental tissue samples collected from three to five bitches on days 8–12 (pre-implantation), 18–25 (post-implantation), and 35–40 (mid-gestation) of pregnancy and during the prepartal luteolysis. Additionally, ten mid-pregnant bitches were treate
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Jia, Huijuan, Moe Miyoshi, Xuguang Li, et al. "The Epigenetic Legacy of Maternal Protein Restriction: Renal Ptger1 DNA Methylation Changes in Hypertensive Rat Offspring." Nutrients 15, no. 18 (2023): 3957. http://dx.doi.org/10.3390/nu15183957.

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Nutrient imbalances during gestation are a risk factor for hypertension in offspring. Although the effects of prenatal nutritional deficiency on the development of hypertension and cardiovascular diseases in adulthood have been extensively documented, its underlying mechanisms remain poorly understood. In this study, we aimed to elucidate the precise role and functional significance of epigenetic modifications in the pathogenesis of hypertension. To this end, we integrated methylome and transcriptome data to identify potential salt-sensitive hypertension genes using the kidneys of stroke-prone
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Zschockelt, Lina, Olga Amelkina, Marta J. Siemieniuch, et al. "Synthesis and reception of prostaglandins in corpora lutea of domestic cat and lynx." Reproduction 152, no. 2 (2016): 111–26. http://dx.doi.org/10.1530/rep-16-0180.

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Felids show different reproductive strategies related to the luteal phase. Domestic cats exhibit a seasonal polyoestrus and ovulation is followed by formation ofcorpora lutea(CL). Pregnant and non-pregnant cycles are reflected by diverging plasma progesterone (P4) profiles. Eurasian and Iberian lynxes show a seasonal monooestrus, in which physiologically persistent CL (perCL) support constantly elevated plasma P4 levels. Prostaglandins (PGs) represent key regulators of reproduction, and we aimed to characterise PG synthesis in feline CL to identify their contribution to the luteal lifespan. We
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Thibodeau, Jean-François, Rania Nasrallah, Anthony Carter, et al. "PTGER1 Deletion Attenuates Renal Injury in Diabetic Mouse Models." American Journal of Pathology 183, no. 6 (2013): 1789–802. http://dx.doi.org/10.1016/j.ajpath.2013.08.022.

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Nuttinck, Fabienne, Brigitte Marquant-Le Guienne, Laetitia Clément, Pierrette Reinaud, Gilles Charpigny, and Bénédicte Grimard. "Expression of genes involved in prostaglandin E2 and progesterone production in bovine cumulus–oocyte complexes during in vitro maturation and fertilization." REPRODUCTION 135, no. 5 (2008): 593–603. http://dx.doi.org/10.1530/rep-07-0453.

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Prostaglandin E2(PGE2) and progesterone appear to be critical mediators of cumulus expansion and the resumption of oocyte meiosis. The aim of this study was to identify the types of prostaglandin E synthase (PTGES) expressed in the bovine cumulus–oocyte complex (COC), to characterize their temporal expression during the periconceptional interval using anin vitromodel of maturation (IVM) and fertilization (IVF), and to compare their expression with the level of steroidogenic gene expression. Real-time RT-PCR analysis revealed that enzymes related to the PGE2biosynthesis pathway were mainly expr
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Waclawik, Agnieszka, Piotr Kaczynski, and Henry N. Jabbour. "Autocrine and Paracrine Mechanisms of Prostaglandin E2 Action on Trophoblast/Conceptus Cells through the Prostaglandin E2 Receptor (PTGER2) during Implantation." Endocrinology 154, no. 10 (2013): 3864–76. http://dx.doi.org/10.1210/en.2012-2271.

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The conceptus and endometrium secrete large amounts of prostaglandin E2 (PGE2) into the porcine uterine lumen during the periimplantation period. We hypothesized that PGE2 acts on conceptus/trophoblast cells through auto- and paracrine mechanisms. Real-time RT-PCR analysis revealed that PGE2 receptor (PTGER)2 mRNA was 14-fold greater in conceptuses/trophoblasts on days 14–25 (implantation and early placentation period) vs preimplantation day 10–13 conceptuses (P < .05). Similarly, expression of PTGER2 protein increased during implantation. Conceptus expression of PTGER4 mRNA and protein
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Jamshed, Laiba, Genevieve A. Perono, Shanza Jamshed, Kim Ann Cheung, Philippe J. Thomas, and Alison Holloway. "The Effects of Naphthenic Acids on Tryptophan Metabolism and Peripheral Serotonin Signalling." Journal of the Endocrine Society 5, Supplement_1 (2021): A493. http://dx.doi.org/10.1210/jendso/bvab048.1008.

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Abstract Introduction: Serotonin produced in the periphery has been shown to affect glucose and lipid homeostasis. The availability of the amino acid tryptophan, the precursor of serotonin, affects serotonin availability. In addition, the metabolism of tryptophan via the kynurenine pathway produces physiologically active metabolites which have been shown to be altered under conditions of increased adiposity and dysglycemia. There is now evidence demonstrating some environmental xenobiotics, known to affect glucose and lipid homeostasis, can also alter serotonin production and key components of
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Tesis sobre el tema "PTGER1"

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Heumann, Tina [Verfasser], and Ursula [Akademischer Betreuer] Klingmüller. "Characterization of the novel pericyte receptors S1PR3 and PTGER2 / Tina Heumann ; Betreuer: Ursula Klingmüller." Heidelberg : Universitätsbibliothek Heidelberg, 2017. http://d-nb.info/1178010465/34.

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Mesa, Solís Julio. "Human prostaglandin reductase 1 (PTGR1): Substrate specificity, site-directed mutagenesis and catalytic mechanism." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/394081.

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Ello, Serge. "Préparation de catalyseurs bimétalliques PtGe/Al2O3 par voie organométallique pour une application en reformage." Poitiers, 2005. http://www.theses.fr/2005POIT2303.

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L'objectif de ce travail a été axé sur la préparation des catalyseurs bimétalliques Pt-Ge/Al2O3 puis l'évaluation de leurs performances pour une éventuelle application en reformage. Les catalyseurs ont été préparés par greffage organométallique. Cette technique de préparation a permis de déposer de très faible quantité de germanium à la surface du catalyseur parent Pt/Al2O3. Ces catalyseurs ont ensuite subi diverses techniques de caractérisation : microscopie électronique à transmission (MET), chimisorption d'hydrogène, chimisorption de monoxyde de carbone puis des tests de caractérisation : l
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Berry-Mortada, Fadwa. "Stabilité des plasmides recombinés en cellules libres et immobilisées : développement d'un système à double réacteur en continu en vue d'une surproduction de catéchol 2,3-dioxygénase." Compiègne, 1989. http://www.theses.fr/1989COMPD211.

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Dans cette étude, l'effet de certains facteurs, comme les caractéristiques génétiques des vecteurs la concentration de l'inoculum, les conditions de culture, etc. . . . Sur la stabilité de différents vecteurs (portant le gène sous contrôle de différents promoteurs) et la production de catéchol 2,3-dioxygénase en culture de cellules libres et immobilisées a été étudié. Nous avons montré d'une part, qu'en suspension les plasmides sont maintenus avec un degré variable de stabilité dans les souches d'E. Coli. L'instabilité des plasmides pTG201 et pTG205 est surtout attribuée à la forte expression
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Pasciuto, Giulia [Verfasser], and Stephan [Akademischer Betreuer] Brand. "Neue Krankheitssuszeptibilitätsgene bei chronisch entzündlichen Darmerkrankungen und deren phänotypische Auswirkungen : der Einfluss von Polymorphismen im PTGER4-, PHOX2B-, NCF4- und FAM92B-Gen und in der chromosomalen Region 10q21.1 auf die Suszeptibilität und den Phänotyp von chronisch entzündlichen Darmerkrankungen / Giulia Pasciuto ; Betreuer: Stephan Brand." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2017. http://d-nb.info/1136270590/34.

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MAZZOLA, Silvia. "Mutation search and association study of candidate genes in non melanoma skin cancer after organ transplantation." Doctoral thesis, 2011. http://hdl.handle.net/11562/349795.

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La Prostaglandina E2 (PGE2) è coinvolta in diversi processi fisiopatologici. PGE2 è una molecola chiave nel processo di cancerogenesi, essendo coinvolta nella proliferazione cellulare, nell'angiogenesi, nella sorveglianza immunitaria e nell’apoptosi. La sintesi di PGE2 richiede tre enzimi che agiscono in sequenza: la Fosfolipasi A2, la cicloossigenasi e la sintetasi della prostaglandina E. La Fosfolipasi A2 (PLA2) permette il rilascio di acido arachidonico (AA) dai fosfolipidi di membrana, la cicloossigenasi (COX) converte l’AA a PGH2, che viene isomerizzato a PGE2 dalla sintasi della prosta
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WU, PEI-JU, and 吳佩儒. "PTGFRN Expression Correlate with WHO Grades in Gliomas." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/f88244.

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碩士<br>國防醫學院<br>病理及寄生蟲學研究所<br>106<br>Recent studies have shown Prostaglandin F2 Receptor Inhibitor (PTGFRN) is related to angiogenesis and tumor overgrowth in human. De novo glioblastoma multiforme (GBM) is the most common and highly malignant form of brain tumor. It is aggressive and challenging to be treated. Due to their finger-like tentacles, they are difficult to be completely removed by surgery. Median survival time for patients receiving only surgical resection is 4 months. The median survival time is extended to 9 to 10 months with conventional radiation therapy. The current standard tr
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Mala, Uchurappa. "An integrative analysis of Cell Adhesion Molecules (CAMs) in Glioma: The Essential role of PTGFRN and ASTN1 in Glioma and Glioma Stem-like Cells." Thesis, 2020. https://etd.iisc.ac.in/handle/2005/4658.

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The central nervous system tissue contains neural stem cells which differentiate and give rise to the neurons and glial cells. The glial cells maintain neurons by providing nutrients, physical support and protection. Unlike neurons, glial cells retain their capacity to divide and proliferate throughout the life span of an individual. During proliferation of glial cells, dysregulation in cellular processes that control growth leads to formation of glial neoplasms or gliomas. The glial tumors are classified based on the predominant cell type; astrocytomas that originate mainly from astrocytes, o
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Guo, Chien-Jung, and 郭千榕. "The role of Glucocorticoid receptor(GR) in PTGR2 regulation." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/u2p5xy.

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碩士<br>國立臺灣大學<br>分子醫學研究所<br>105<br>Adipocyte differentiation is an elegant, complicated process involving sequentially activation of thousands of transcriptional factors. Our group previously discovered a novel enzyme, called prostaglandin reductase 2 (PTGR2) through mRNA differential display. PTGR2 is an oxidoreductase which catalyze 15-keto PGE2 to 13,14-dihydro-15-keto PGE2 as final product. In functional study, overexpression PTGR2 rather than its catalytic mutant inhibited adipocyte differentiation and relatively triacylglycerol content,which suggest a role of PTGR2 in adipogenesis. Additi
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Chen, Kuan-Ju, and 陳冠如. "Triage of Endometrial Atypical Hyperplasia by DNA Methylation of SOX1, HS3ST2, AJAP1 and PTGDR." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/35059509426421457312.

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碩士<br>國防醫學院<br>病理及寄生蟲學研究所<br>100<br>Endometrial carcinoma (EC) is the one of the most common cancers in female genital tract worldwide. It can be classified into two major subtypes with respect to histopathology, cell biology and clinical course. Epigenetic aberration is known to be important in human carcinogenesis. Promoter methylation status of SOX1, HS3ST2, AJAP1 and PTGDR, was evaluated in 20 endometrial carcinomas (EC) and normal endometrial tissue by methylation specific PCR. These 4 genes had higher methylation value in patients with EC than in normal controls of AJAP1, PTGDR, HS3ST2,
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Capítulos de libros sobre el tema "PTGER1"

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"PTGER2." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_103155.

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"Ptgs1." In Encyclopedia of Pain. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-28753-4_101923.

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Makin-Iniesta, F. "Kinetic Study of pTG201 Plasmid Stability in Escherichia coli." In 1988. De Gruyter, 1988. http://dx.doi.org/10.1515/9783112581803-003.

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Lea, Robert, Yashvant Jani, GianGuido Rizzotto, et al. "Operations Research." In Handbook of Fuzzy Computation. Taylor & Francis, 1998. http://dx.doi.org/10.1201/9781420050394.ptg1.

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"Post-Transcriptional Gene Regulation (PTGR)." In Encyclopedia of Systems Biology. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_101172.

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Fernandez, Mini, and P. Shravani Shriya. "In-Silico Studies of MIF, MIEN 1, NAA40, RALB, and PTGES Proteins Involved in Colorectal Cancer." In Convergence of Technology & Biology - Transforming Life Sciences. Shanlax Publications, 2025. https://doi.org/10.34293/ctbtls.2025.ch009.

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Colorectal cancer is the second leading cause of cancer-related deaths, emerging as one of the major causes of morbidity and mortality worldwide. Our study intends to focus on 5 proteins; MIF, MIEN 1, NAA40, RALB, and PTGES that have been experimentally proven to play a key role in the progression of colorectal cancer. The selected proteins and their template sequences along with structures were retrieved from NCBI, UniProt, BLAST, and RCSB PDB followed by alignment analysis in Clustal Omega. The models of the proteins were generated and validated using Swiss-Model, SAVES v6.0, and ProSA. The active site was predicted with the employment of CASTp. Docking of the protein with the selected ligands was performed using Vina in PyRx and the most suitable confirmation of the ligand was selected via splitting the ligand using AutoDock vina. Further details of protein-ligand interactions were visualized in BioVia Discovery Studio. In silico analysis revealed the topological features of various binding mechanisms of the drug with respective proteins, reflecting the possible interactions that can reduce the progression of CRCs acting as targeted agents for suppressing tumor growth. However, further experimental analysis including in vivo, in vitro, and clinical trials are required to validate the possible outcome and determine its success rate.
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Actas de conferencias sobre el tema "PTGER1"

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Bayraktar, Emine, Cristian Rodriguez-Aguayo, Junhua Mai, et al. "Abstract 4668: Silencing PTGER3 enhances chemotherapeutic responses." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-4668.

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Dong, Sheng, and Xiaoli Hao. "Statistical Analysis of Ocean Environmental Conditions With PTGEVD." In ASME 2004 23rd International Conference on Offshore Mechanics and Arctic Engineering. ASMEDC, 2004. http://dx.doi.org/10.1115/omae2004-51615.

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Poisson Trivariate Gumbel Extreme Value Distribution (PTGEVD), a multivariate from of the Compound Extreme Value Distribution, is presented to solve for the ocean environmental design criteria in this paper. The proposed model is combined with a discrete distribution of storm frequency and a continuous trivariate extreme value distribution of environmental conditions simultaneously occurred in storm processes. Different from traditional univariate design method, the proposed design method with PTGEVD can reflect the combined effect of multi-loads on offshore structures and result in reasonable
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Gui, H., D. Hu, P. Sleiman, et al. "Genome-Wide Association Study of Asthma Exacerbation in African Americans Identify PTGER3 as New Susceptibility Gene." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a3044.

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Hess, T., L. Hamann, YK Vashist, et al. "Evidence for PTGER4, PSCA and MBOAT7 as risk genes for gastric cancer on the genome and transcriptome level." In Viszeralmedizin 2017. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1604759.

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Bayraktar, Emine, Cristian Rodriguez-Aguayo, Zahid Siddik, and Gabriel Lopez-Berestein. "Abstract 2066: Delivery of 2`F-PS2 PTGER3 siRNA-DOPC enhances anti-tumoral activity in cisplatin resistant ovarian cancer model." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-2066.

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Schlegel, Anne, Oliver Hasinger, Selina Esche, Melanie Martini, Thomas König, and Gunter Weiss. "Abstract 2260: Classification of patients with lung cancer and benign lung disease via assessment of DNA methylation of SHOX2 and PTGER4 in plasma." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-2260.

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Silva, Gustavo Figueiredo da, Bruno Mattei Lopes, Vinicius Moser, and Leslie Ecker Ferreira. "Impact of pharmacogenetics on aspirin resistance: a systematic review." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.663.

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Background: Pharmacogenetics promises better control of diseases, such as Cardiovascular disease (CVD). Acetylsalicylic acid, aspirin, prevents the formation of an activating agent of platelet aggregation and vasoconstriction, and it is used to prevent CVD. Nevertheless, patients may have treatment failure, causing recurrence and increased mortality, due to medication adherence, drug- drug interactions, aspirin-independent thromboxane A2 synthesis or genetic variants. In this sense, genetic variants have been related with aspirin resistance (AR). Objective: To evaluate the evidence of impact o
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Habermann, Nina, Martha L. Slattery, Elizabeth M. Poole, et al. "Abstract 3757: PTGS1 and PTGS2 polymorphisms, fatty acid intake, and risk of colon and rectal cancer." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3757.

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Marquez, Jorge, Jianping Dong, Chun Dong, and Ginette Serrero. "Abstract LB116: Prostaglandin F2 Receptor Negative Regulator (PTGFRN) is a novel target to inhibit tumor growth via antibody drug conjugate." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-lb116.

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Wagner, Michael J., Sanford A. Klein, and Douglas T. Reindl. "Simulation of Utility-Scale Central Receiver System Power Plants." In ASME 2009 3rd International Conference on Energy Sustainability collocated with the Heat Transfer and InterPACK09 Conferences. ASMEDC, 2009. http://dx.doi.org/10.1115/es2009-90132.

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The operation of solar energy systems is necessarily transient. Over the lifetime of a concentrating solar power plant, the system operates at design conditions only occasionally, with the bulk of operation occurring under part-load conditions depending on solar resource availability. Credible economic analyses of solar-electric systems requires versatile models capable of predicting system performance at both design and off-design conditions. This paper introduces new and adapted simulation tools for power tower systems including models for the heliostat field, central receiver, and the power
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