Tesis sobre el tema "Psychotic symptoms"
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Sandt, Arthur Ralph. "Hedonic Functioning and Subthreshold Psychotic Symptoms". Diss., Temple University Libraries, 2013. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/164124.
Texto completoPh.D.
Schizophrenia is a debilitating disorder with an array of affective, cognitive, and behavioral consequences. In addition to these impairments, research suggests that there is a distinct pattern of hedonic functioning in schizophrenia that may contribute to some of the most intractable symptoms of the disorder, the negative symptoms. Specifically, individuals with schizophrenia appear to experience deficient levels of pleasure during anticipation of a pleasurable stimulus, while experiencing typical levels of pleasure while directly engaged with a pleasurable stimulus. Despite these findings, it is unclear whether hedonic functioning deficits occur in individuals with subthreshold levels of psychotic symptoms and/or in individuals at clinical high risk for the disorder. The purpose of this study was to examine hedonic functioning in relation to the continuum of psychotic symptoms in a college undergraduate student sample, and in those at clinical risk for schizophrenia. Participants were 679 students who completed self-report measures of current psychotic-like experiences, and trait-like components of hedonic functioning (i.e., anticipatory and consummatory pleasure). Consistent with study hypotheses, deficits in anticipatory pleasure, but not in consummatory pleasure, were significantly associated with increased clinical risk for schizophrenia. However, this relation was found exclusively among women in the sample, whereas men did not show a significant relation between anticipatory pleasure deficits and clinical high-risk. Furthermore, anticipatory pleasure deficits were not significantly associated with increases in the number of positive psychotic symptoms endorsed. Moreover, consummatory pleasure was not associated with increases in the number of subthreshold positive psychotic symptoms, nor was there a relation with the number of distressing positive psychotic symptoms or clinical risk status. The present study provides the first examination of the relation between hedonic functioning and subthreshold psychotic symptoms, as well as the relation with clinical high-risk for psychosis. These findings suggest that anticipatory pleasure deficits may be more closely related to increased clinical risk for psychosis among women rather than increases in psychotic symptoms in the general population. Anticipatory pleasure deficits may be a useful target for intervention and prevention techniques among those at clinical risk for psychosis, especially in female at risk populations. Additional longitudinal studies will be essential for testing whether anticipatory pleasure deficits predict the occurrence of future psychotic disorders among those at high risk for the disorder in order to improve early identification and early intervention efforts in this population.
Temple University--Theses
Spauwen, Janneke, Lydia Krabbendam, Roselind Lieb, Hans-Ulrich Wittchen y Os Jim van. "Impact of psychological trauma on the development of psychotic symptoms: relationship with psychosis proneness". Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-108608.
Texto completoSpauwen, Janneke, Lydia Krabbendam, Roselind Lieb, Hans-Ulrich Wittchen y Os Jim van. "Impact of psychological trauma on the development of psychotic symptoms: relationship with psychosis proneness". Technische Universität Dresden, 2006. https://tud.qucosa.de/id/qucosa%3A26761.
Texto completoBallard, C. G. "Depression and psychotic symptoms in dementia sufferers". Thesis, University of Leicester, 1995. http://hdl.handle.net/2381/34340.
Texto completoSpengler, Peter A. y Hans-Ulrich Wittchen. "Procedural validity of standardized symptom questions for the assessment of psychotic symptoms". Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-103807.
Texto completoPreston, Neil Joseph. "The causal predominance of psychotic experience". Thesis, Curtin University, 2003. http://hdl.handle.net/20.500.11937/2307.
Texto completoPreston, Neil Joseph. "The causal predominance of psychotic experience". Curtin University of Technology, School of Psychology, 2003. http://espace.library.curtin.edu.au:80/R/?func=dbin-jump-full&object_id=14961.
Texto completoIt was argued that poor thinking styles that lead to distortion in feelings of mistrust evident in the paranoia symptom, in turn led to deterioration in cognition. Other symptoms did not demonstrate a cross influential effect. Previous research suggesting that symptoms act independently of each other over time supports the results of independence of the other symptoms. Further research was suggested by linking different levels of psychosis research of the aetiological factors (e.g. genetic factors), neuropathology (e.g., reduced synapse density) and phenomenology (e.g., positive and negative symptoms) into an integrative framework. It was suggested that structural equation modelling as exemplified in the thesis could be used as a technique to examine how these differing levels could be investigated under a unified theory of psychosis based upon the neurodevelopmental hypothesis.
Hides, Leanne y n/a. "An Examination of the Influence of Cannabis Use on Psychotic Symptom Exacerbation and Relapse in Early Psychosis". Griffith University. School of Applied Psychology, 2003. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20030922.130049.
Texto completoHides, Leanne. "An Examination of the Influence of Cannabis Use on Psychotic Symptom Exacerbation and Relapse in Early Psychosis". Thesis, Griffith University, 2003. http://hdl.handle.net/10072/366456.
Texto completoThesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Applied Psychology
Full Text
Henquet, Cécile, Lydia Krabbendam, Janneke Spauwen, Charles Kaplan, Roselind Lieb, Hans-Ulrich Wittchen y Os Jim van. "Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people". Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-120761.
Texto completoHenquet, Cécile, Lydia Krabbendam, Janneke Spauwen, Charles Kaplan, Roselind Lieb, Hans-Ulrich Wittchen y Os Jim van. "Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people". Technische Universität Dresden, 2004. https://tud.qucosa.de/id/qucosa%3A27119.
Texto completoReeves, Lauren Elizabeth. "Cannabis use and attenuated positive psychotic symptoms: A multiple mediation model". Diss., Temple University Libraries, 2017. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/465547.
Texto completoPh.D.
Cannabis use has been associated with various psychosis outcomes, including psychotic disorders, the clinical high risk period of psychosis, and subthreshold measures of psychotic symptoms in non-clinical samples, such as attenuated positive psychotic symptoms (APPS). The present study examined whether individual- and contextual-level factors account for the relationship between cannabis use and psychosis. Specifically, we hypothesized that the relationship between cannabis and psychosis would be mediated by social functioning; negative, depression, anxiety, and aggression symptoms; context of cannabis use; and motivations for cannabis use. Nine hundred and forty-five young adults ages 18-35 years (M = 20.1 years, 24.4% male) completed self-report questionnaires: the Prodromal Questionnaire, Marijuana Use Form, Social Functioning Scale, Center for Epidemiologic Studies Depression Scale, State-Trait Anxiety Inventory-Trait Form-Anxiety Subscale, Social Phobia Scale, Life History of Aggression Scale, Reasons for Use scale, and Drug Use Frequency questionnaire. Psychosis outcomes included a dimensional measure of APPS and a dichotomous measure indicating potential higher/lower risk for psychosis, based on number of distressing symptoms endorsed (i.e., D-APPS status). A multiple mediation framework was used, and significance of mediators was evaluated through estimating the significance of indirect effects using bootstrapped confidence intervals. Increases in negative and aggression symptoms mediated the relationship between higher cannabis use and increases in APPS. Negative and aggression symptoms, context of cannabis use, and using cannabis to cope with unpleasant affect mediated the relationship between cannabis use and high-D-APPS status. Results indicate that individual and contextual-level characteristics may contribute to the relationship between cannabis use and psychosis.
Temple University--Theses
Bo, Borghild. "The development and preliminary evaluation of a self-administered screening instrument for first rank symptoms and basic symptoms in psychotic and non psychotic disorders". Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 1999. https://ro.ecu.edu.au/theses/1243.
Texto completoCreese, Byron. "Genetic epidemiology of psychotic symptoms and their treatment in dementia". Thesis, King's College London (University of London), 2014. https://kclpure.kcl.ac.uk/portal/en/theses/genetic-epidemiology-of-psychotic-symptoms-and-their-treatment-in-dementia(65565986-7989-4e9d-9905-4f73117ad08b).html.
Texto completoGaudiano, Brandon A. Herbert James D. "Acceptance and commitment therapy for psychiatric inpatients with psychotic symptoms /". Philadelphia, Pa. : Drexel University, 2004. http://dspace.library.drexel.edu/handle/1860/295.
Texto completoCooper, Shanna. "EXPERIENTIAL NEGATIVE SYMPTOMS IN YOUNG ADULTS ENDORSING PSYCHOTIC-LIKE EXPERIENCES". Diss., Temple University Libraries, 2018. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/517180.
Texto completoPh.D.
While many studies of risk factors for psychosis focus on positive symptoms, such as subthreshold levels of hallucinations and delusions, fewer studies have examined negative symptoms in the early course of the schizophrenia or other psychotic disorders. This relative lack of focus on the role of negative symptoms is problematic, given findings that negative symptoms, such as a loss of motivation and pleasure (MAP), are associated with a more persistent and impairing course of psychosis, and tend to appear earlier in the development of psychotic symptoms. Psychotic disorders, which afflict approximately 3-5% of the population, tend to emerge in late adolescence/early adulthood and are among the most debilitating and costly of mental disorders. The current project explored three areas of negative symptoms in young adults who demonstrated a range of psychotic-like experiences (PLEs). First, a review of the literature pertaining to negative symptoms across the span of psychosis was conducted. Second, we tested whether experiential negative symptoms – specifically MAP deficits – were associated with increases in PLEs, including those that are experienced as distressing (PLEDs). Third, we examined the potential influence of episodic memory performance factors on the relationship between MAP symptoms and PLEs/PLEDs. Collectively, this project highlights the importance of including negative symptoms (i.e., MAP deficits) and/or cognitive performance (i.e., associative/relational learning/memory) outcomes when evaluating people with PLEs/PLEDs to identify those who may be at greater risk for developing a psychotic disorder.
Temple University--Theses
Law, Hing-kiu Irene. "Help-seeking pathways of parents whose adolescent children manifest psychotic symptoms /". View the Table of Contents & Abstract, 2006. http://sunzi.lib.hku.hk/hkuto/record/B36785878.
Texto completoLaw, Hing-kiu Irene y 羅慶翹. "Help-seeking pathways of parents whose adolescent children manifest psychotic symptoms". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B45014528.
Texto completoGonterman, Andrea R. "The relationships between insight, psychopathological symptoms, and neurocognitive function in psychotic disorders". Thesis, University of North Texas, 2001. https://digital.library.unt.edu/ark:/67531/metadc3054/.
Texto completoCasstevens, Willa Jeanne. "Evaluation of a mentored self-help intervention for the management of psychotic symptoms". FIU Digital Commons, 2006. http://digitalcommons.fiu.edu/etd/2070.
Texto completoThewissen, Viviane Hubertine Marie. "Understanding the psychology of positive psychotic symptoms an epidemiological and momentary assessment approach /". [Maastricht] : Maastricht : Universitaire Pers Maastricht ; University Library, Universiteit Maastricht [host], 2007. http://arno.unimaas.nl/show.cgi?fid=9198.
Texto completoHomer, Hanne Margareta. "The waxing and waning of psychotic symptoms and co-fluctuating source memory impairment". Thesis, University of East Anglia, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.251895.
Texto completoVenneri, Annalena. "A study of psychotic symptoms in Alzheimer's disease : a cognitive and neuroimaging approach". Thesis, University of Aberdeen, 1999. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU116371.
Texto completoWeinberg, Laura. "Living a valued life with psychosis : the relationship between psychotic symptoms, illness beliefs, experiential avoidance and success at valued living". Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/29419.
Texto completoSanderson, Victoria. "Post-Secondary Students with Symptoms of Psychosis: A Mixed-Methods Systematic Review". Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/39788.
Texto completoKuzenko, Nina, Jitender Sareen, Katja Beesdo-Baum, Axel Perkonigg, Michael Höfler, James Simm, Roselind Lieb y Hans-Ulrich Wittchen. "Associations Between Cocaine, Amphetamine or Psychedelic Use and Psychotic Symptoms in a Community Sample". Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-118271.
Texto completoKuzenko, Nina, Jitender Sareen, Katja Beesdo-Baum, Axel Perkonigg, Michael Höfler, James Simm, Roselind Lieb y Hans-Ulrich Wittchen. "Associations Between Cocaine, Amphetamine or Psychedelic Use and Psychotic Symptoms in a Community Sample". Technische Universität Dresden, 2011. https://tud.qucosa.de/id/qucosa%3A27049.
Texto completoSpengler, Peter A. y Hans-Ulrich Wittchen. "Procedural validity of standardized symptom questions for the assessment of psychotic symptoms: A comparison of the DIS with two clinical methods". Technische Universität Dresden, 1988. https://tud.qucosa.de/id/qucosa%3A26471.
Texto completo丁錫全 y Sik-chuen Dick Ting. "Relationship of psychotic symptoms to sex offending: a retrospective study of sex offenders with mentaldisorders". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B39558162.
Texto completoMapplebeck, Clare. "The experience of change and psychological growth in people with psychotic symptoms : a phenomenological approach". Thesis, University of Nottingham, 2010. http://eprints.nottingham.ac.uk/11654/.
Texto completoTing, Sik-chuen Dick. "Relationship of psychotic symptoms to sex offending a retrospective study of sex offenders with mental disorders /". Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/HKUTO/record/B39558162.
Texto completoNorman, Catherine. "Thinking about thinking : an exploration of metacognitive factors in the development and maintenance of positive psychotic symptoms". Thesis, University of Southampton, 2013. https://eprints.soton.ac.uk/359249/.
Texto completoEblin, Joshua J. "Examination of the Validity of the Thought and Perception Assessment System: A Behavioral Measure of Psychotic Symptoms". University of Toledo / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1419279941.
Texto completoEriksson, Linda Kristina. "Do psychosocial interventions for psychotic disorders improve quality of life in adults with psychotic disorders in forensic settings? : a systematic review and narrative synthesis ; and, Modified metacognitive training for negative symptoms in psychosis : a feasibility study". Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31197.
Texto completoRogers, Andrew. "Attributional style, theory of mind ability and episodic memory functioning : an integrated cognitive neuropsychological account of psychotic symptoms". Thesis, University of Surrey, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244780.
Texto completoSchuller, Stefan. "Helping to make sense : an evaluation of team-based cognitive-behavioural formulation workshops for recent onset psychotic symptoms". Thesis, Open University, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441154.
Texto completoKuepper, Rebecca, Os Jim van, Roselind Lieb, Hans-Ulrich Wittchen, Michael Höfler y Cécile Henquet. "Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study". Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-120779.
Texto completoKuepper, Rebecca, Os Jim van, Roselind Lieb, Hans-Ulrich Wittchen, Michael Höfler y Cécile Henquet. "Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study". Technische Universität Dresden, 2011. https://tud.qucosa.de/id/qucosa%3A27121.
Texto completoClark-Papasavas, Chloe Melissa. "Characterising the neuropsychological profile of psychotic symptoms in Alzheimer's disease and imaging D2/3 receptor occupancy during treatment". Thesis, King's College London (University of London), 2014. https://kclpure.kcl.ac.uk/portal/en/theses/characterising-the-neuropsychological-profile-of-psychotic-symptoms-in-alzheimers-disease-and-imaging-d23-receptor-occupancy-during-treatment(e96bd2b4-7a12-4f4a-923a-637d857bbc2d).html.
Texto completoLapworth, Kely Narelle. "An Investigation of Aggression in Methamphetamine Users". Thesis, Griffith University, 2011. http://hdl.handle.net/10072/366564.
Texto completoThesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Psychology
Griffith Health
Full Text
Valton, Vincent. "Impaired reinforcement learning and Bayesian inference in psychiatric disorders : from maladaptive decision making to psychosis in schizophrenia". Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/21097.
Texto completoHaggarty, David. "Exploring the delivery of family interventions to people facing recent-onset psychotic symptoms : the experience of navigating the family system". Thesis, University of Leicester, 2016. http://hdl.handle.net/2381/38223.
Texto completoHeuvelman, Hein Hendrik Pieter. "Ethnicity and psychosis : an investigation of the validity of psychosis screening instruments in the context of cross-cultural population-based survey research". Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/ethnicity-and-psychosis--an-investigation-of-the-validity-of-psychosis-screening-instruments-in-the-context-of-crosscultural-populationbased-survey-research(1019c614-3576-4e4b-8487-41a3470c8371).html.
Texto completoBarragán, Farfán Janis Marcela. "Psychotic-like experiences and psychometric schizotypy: their relationships with depressive symptoms and theory of mind in adolescents from the general population". Doctoral thesis, Universitat Autònoma de Barcelona, 2013. http://hdl.handle.net/10803/129120.
Texto completoIndividuals who report psychotic-like experiences (PLEs) are at significantly increased risk for clinical psychotic disorders. However, associations between PLEs and non-psychotic disorders indicate that the clinical relevance of PLEs is not limited to psychosis and thus, investigating the role of additional symptoms, such as depression, may improve the capacity to predict risk of developing psychotic disorders. Additionally, studying theory of mind (ToM) abilities, one of the cognitive areas impaired in schizophrenic patients, in adolescents from the general population may contribute to clarify whether ToM deficits are present in at-risk individuals before the onset of the illness and derived impairments. Evidence suggests that ToM impairments are not exclusive of symptomatic patients, and that further understanding of the nature of ToM dysfunction in schizophrenia might be achieved through examination of ToM impairments from the early phases and even before the onset of the illness. Objectives: this thesis was aimed at (1) examining the presence of both positive and negative PLEs and their association with depressive symptoms in a community sample of adolescents; (2) analysing the presence of subtypes of positive and negative PLEs dimensions in adolescents of the community, and (3) exploring ToM functioning, its association with psychometric schizotypy, PLEs, and depressive symptoms, in a sample of adolescents from the general population. Method: participants in this cross-sectional study were adolescents aged between 13 and 17 years, attending compulsory secondary education in schools from Barcelona, Spain. To establish the presence of subtypes of positive and negative PLEs, separate principal component factor analyses of the CAPE positive and negative subscales were performed. Multiple linear regression analysis was conducted to examine the association between specific CAPE positive and negative PLE subtypes and depressive symptoms. Results: PLEs and psychometric schizotypy dimensions were present in this community sample of adolescents. Four factors of positive symptoms (persecutory ideation, grandiose thinking, first-rank-hallucinatory, and self-referential thinking) and three factors of negative symptoms (social withdrawal, affective flattening, and avolition) emerged from the analysis. Different relationships between subtypes of positive PLEs and depressive symptoms were found: persecutory ideation and first-rank/hallucinatory experiences related to higher scores on the depressive symptoms scale whilst grandiose thinking related to lower scores on depression. No association with self-referential thinking was found. Associations between subtypes of the negative dimension and depression were also found: social withdrawal and avolition were positively associated with the self-report of depressive symptoms, while affective flattening did not relate to depression. No differences were found in ToM abilities in adolescents with higher global scores on schizotypy or PLEs relative to those with lower global scores. Higher scores on the unusual experiences subscale assessing positive schizotypy and on first-rank experiences were associated with poorer ToM ability, whereas persecutory beliefs were related to better ToM performance. No association was found between ToM and magical thinking or hallucinatory experiences. Negative PLEs or negative schizotypy were not related to ToM abilities. In addition, an association between better mentalising abilities and higher impulsive nonconformity was found. Conclusions: these findings support the view that not all types of positive and negative PLEs in adolescence are associated with depression and, therefore, may not confer the same vulnerability for psychotic disorders. ToM impairments are not restricted to the acute phase of a psychotic disorder, and may be associated to positive schizotypy and first-rank experiences. These findings constitute evidence indicating that ToM impairments can be identified during adolescence before the onset of any psychotic disease.
Jaya, Edo Sebastian Verfasser] y Tania [Akademischer Betreuer] [Lincoln. "The interplay between social factors and psychotic symptoms : Cognitive vulnerability and affective pathway in focus / Edo Sebastian Jaya ; Betreuer: Tania Lincoln". Hamburg : Staats- und Universitätsbibliothek Hamburg, 2017. http://d-nb.info/1136719903/34.
Texto completoSchlier, Björn [Verfasser] y Tania [Akademischer Betreuer] Lincoln. "Psychotic symptoms in ambulatory assessment and longitudinal studies : Development of state measures and evaluation of stress-related predictors / Björn Schlier ; Betreuer: Tania Lincoln". Hamburg : Staats- und Universitätsbibliothek Hamburg, 2019. http://d-nb.info/1187444820/34.
Texto completoWigman, Johanna T. W., Nierop Martine van, Wilma A. M. Vollebergh, Roselind Lieb, Katja Beesdo-Baum, Hans-Ulrich Wittchen y Os Jim van. "Evidence That Psychotic Symptoms Are Prevalent in Disorders of Anxiety and Depression, Impacting on Illness Onset, Risk, and Severity – Implications for Diagnosis and Ultra-High Risk Research". Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-129460.
Texto completoWigman, Johanna T. W., Nierop Martine van, Wilma A. M. Vollebergh, Roselind Lieb, Katja Beesdo-Baum, Hans-Ulrich Wittchen y Os Jim van. "Evidence That Psychotic Symptoms Are Prevalent in Disorders of Anxiety and Depression, Impacting on Illness Onset, Risk, and Severity – Implications for Diagnosis and Ultra-High Risk Research". Technische Universität Dresden, 2012. https://tud.qucosa.de/id/qucosa%3A27328.
Texto completoSoares, Walter Barbalho. "Sintomas psicóticos em uma amostra comunitária de idosos sem demência da cidade de São Paulo: incidência e fatores de risco". Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5142/tde-11092017-083150/.
Texto completoBackground: Studies of the incidence of psychotic symptoms in elderly people at risk of dementia are scarce. This is a seven year follow up study aiming to determine the incidence of psychotic symptoms and their correlation with other clinical aspects as well as conversion rates to cognitive impairment. Objectives: To determine the incidence of psychotic symptoms, correlate these symptoms with clinical characteristics and establish the conversion rate to cognitively impaired individuals. Design: Cross-sectional study of a community-based sample of elderly subjects. Setting: City of Sao Paulo, State of Sao Paulo, Brazil. Participants: The original sample was composed of 1,125 individuals aged 60 years and older from a community. Among this sample, 547 subjects were re-evaluated in 2011 and submitted to the same protocol. Of these, 199 did not have psychotic symptoms at phase I and 64 already had psychotic symptoms in 2006. Results: The incidence of at least one psychotic symptom in 7 years was 8.0% (Visual/tactile hallucinations: 4.5%; Persecutory delusions: 3.0%; Auditory hallucinations: 2.5%). Psychotic symptom incidence was associated with epilepsy (OR: 7.75 and 15.83), lower MMSE (OR: 0.72) and reported depression (OR: 6.48). A total of 57.8% of individuals with psychotic symptoms but without dementia at phase I developed cognitive impairment after 7 years (visual/tactile hallucinations were the only psychotic symptom predictive of this impairment - OR: 5.66), which was related to lower MMSE and increased functional impairment. Conclusions: The incidence of psychotic symptoms and the conversion rate to cognitive impairment was in the upper range of previous literature reports. Visual/tactile hallucinations were the most incident symptoms and the only predictive psychotic symptoms for cognitive impairment in 5 years. Important relationships were found between psychotic symptoms incidence and MMSE, epilepsy, reported depression, diabetes and syphilis
Vorspan, Florence. "Mise au point de mesures de variables intermédiaires pour les essais cliniques dans la dépendance à la cocaïne : craving et symptômes psychotiques". Phd thesis, Université René Descartes - Paris V, 2012. http://tel.archives-ouvertes.fr/tel-00744102.
Texto completo