Literatura académica sobre el tema "Proximal interactomics"
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Artículos de revistas sobre el tema "Proximal interactomics"
Sofianatos, Yorgos, Étienne Coyaud y Caroline Demeret. "Towards a three-dimensional mapping of virus-host proximal protein interactions". Project Repository Journal 13, n.º 1 (7 de mayo de 2022): 14–17. http://dx.doi.org/10.54050/prj1318790.
Texto completoHarris, C. Jake, Marion Scheibe, Somsakul Pop Wongpalee, Wanlu Liu, Evan M. Cornett, Robert M. Vaughan, Xueqin Li et al. "A DNA methylation reader complex that enhances gene transcription". Science 362, n.º 6419 (6 de diciembre de 2018): 1182–86. http://dx.doi.org/10.1126/science.aar7854.
Texto completoHaider, Nasir A., Joanna Kelly, Duncan Smith y Claus Jorgensen. "Abstract A099: Utilising interactomics to uncover oncogenic KRAS signalling networks in the context of the tumor microenvironment". Cancer Research 84, n.º 2_Supplement (16 de enero de 2024): A099. http://dx.doi.org/10.1158/1538-7445.panca2023-a099.
Texto completoChua, Xien Yu, Timothy Aballo, William Elnemer, Melanie Tran y Arthur Salomon. "Quantitative Interactomics of Lck-TurboID in Living Human T Cells Unveils T Cell Receptor Stimulation-Induced Proximal Lck Interactors". Journal of Proteome Research 20, n.º 1 (13 de noviembre de 2020): 715–26. http://dx.doi.org/10.1021/acs.jproteome.0c00616.
Texto completoIbarz, Antoni, Ignasi Sanahuja, Waldo G. Nuez-Ortín, Laura Martínez-Rubio y Laura Fernández-Alacid. "Physiological Benefits of Dietary Lysophospholipid Supplementation in a Marine Fish Model: Deep Analyses of Modes of Action". Animals 13, n.º 8 (18 de abril de 2023): 1381. http://dx.doi.org/10.3390/ani13081381.
Texto completoOsagie, Oloruntoba I., Jordann Smakk, Deborah E. Citrin y Travis H. Stracker. "Abstract 4802: Identification of critical hypoxia induced factors in castrate resistant prostate cancer". Cancer Research 83, n.º 7_Supplement (4 de abril de 2023): 4802. http://dx.doi.org/10.1158/1538-7445.am2023-4802.
Texto completoCutler, Jevon, Rahia Tahir, Jingnan Han, Raja Sekhar Nirujogi, Tai-Chung Huang, Xianrong Wong, Saradhi Mallampati et al. "Differential Signaling through p190 and p210 Forms of BCR-ABL Fusion Proteins Revealed By Proteomic Analysis". Blood 126, n.º 23 (3 de diciembre de 2015): 3651. http://dx.doi.org/10.1182/blood.v126.23.3651.3651.
Texto completoRuminski, Kilian, Javier Celis-Gutierrez, Nicolas Jarmuzynski, Emilie Maturin, Stephane Audebert, Marie Malissen, Luc Camoin, Guillaume Voisinne, Bernard Malissen y Romain Roncagalli. "Mapping the SLP76 interactome in T cells lacking each of the GRB2-family adaptors reveals molecular plasticity of the TCR signaling pathway". Frontiers in Immunology 14 (15 de marzo de 2023). http://dx.doi.org/10.3389/fimmu.2023.1139123.
Texto completoKulyyassov, Arman, Gulsamal Zhubanova, Erlan Ramanculov y Vasily Ogryzko. "Proximity Utilizing Biotinylation of Nuclear Proteins in vivo". Central Asian Journal of Global Health 3 (15 de junio de 2015). http://dx.doi.org/10.5195/cajgh.2014.165.
Texto completoChastney, Megan R., Craig Lawless, Jonathan D. Humphries, Stacey Warwood, Matthew C. Jones, David Knight, Claus Jorgensen y Martin J. Humphries. "Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation". Journal of Cell Biology 219, n.º 8 (25 de junio de 2020). http://dx.doi.org/10.1083/jcb.202003038.
Texto completoTesis sobre el tema "Proximal interactomics"
Bachiri, Kamel. "Identification des interactions oncogéniques du Polyomavirus à cellules de Merkel". Electronic Thesis or Diss., Université de Lille (2022-....), 2023. http://www.theses.fr/2023ULILS113.
Texto completoMerkel cell carcinoma (MCC) is an extremely aggressive skin cancer with a high mortality rate. In 80% of cases, this cancer is linked to the presence of the Merkel cell polyomavirus which expresses two viral oncoproteins, small T and a truncated form of large T. The expression of these proteins is sufficient for carcinogenesis, inducing the disruption of cell cycle checkpoints, changes in the epigenetic profile, and immune evasion. The combination of interactomics and proteomics approaches allowed us to identify numerous epigenetic factors related to the T antigens. These studies have also highlighted potential mechanisms involving the regulation of protein stability, gene expression, and genetic stability via an altered DNA damage response pathway. The hypotheses formulated following these analyses were investigated in targeted assays. A link between the peptidyl-prolyl cis/trans isomerase and neddylation was demonstrated. We have thus identified a new potential mechanism for regulating the activity of ubiquitination complexes involving the recruitment of PIN1 to these complexes, thus their isomerization, by neddylation. The study of the EHMT2 functions, an epigenetic regulator of interest, revealed the importance of its role in the DNA damage response in virus positive MCC (VP-MCC). We were able to identify a protective role of tLT and EHMT2 in DNA damages in VP-MCC cells. More specifically, we also report a role of EHMT2 in solving single strand DNA breaks following replication stress. Our works have enabled the discovery of new important mechanisms in VP-MCC oncogenesis, reporting for the first time a central role of tLT in DNA damages management