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Artículos de revistas sobre el tema "Protozoa, Pathogenic"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 30 de julio de 2024

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1

Souza, Wanderley de. "Secretory organelles of pathogenic protozoa." Anais da Academia Brasileira de Ciências 78, no. 2 (June 2006): 271–92. http://dx.doi.org/10.1590/s0001-37652006000200008.

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Secretory processes play an important role on the biology and life cycles of parasitic protozoa. This review focus on basic aspects, from a cell biology perspective, of the secretion of (a) micronemes, rhoptries and dense granules in members of the Apicomplexa group, where these organelles are involved in the process of protozoan penetration into the host cell, survival within the parasitophorous vacuole and subsequent egress from the host cell, (b) the Maurer's cleft in Plasmodium, a structure involved in the secretion of proteins synthesized by the intravacuolar parasite and transported thro

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2

Clipsham, Robert. "Avian pathogenic flagellated enteric protozoa." Seminars in Avian and Exotic Pet Medicine 4, no. 3 (July 1995): 112–25. http://dx.doi.org/10.1016/s1055-937x(05)80035-0.

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3

Ndiaye, Mouhamadou, Khadim Diongue, Mame Cheikh Seck, Mamadou Alpha Diallo, Ekoué Kouevidjin, Aida Sadikh Badiane, and Daouda Ndiaye. "Retrospective Assessment of The Intestinal Protozoan Distribution in Patients Admitted to The Hospital Aristide Le Dantec in Dakar, Senegal, from 2011 to 2020." Parasitologia 3, no. 1 (December 23, 2022): 1–12. http://dx.doi.org/10.3390/parasitologia3010001.

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Infectious parasites, especially the intestinal protozoan parasites, continue to be a major public health problem in Africa, where many of the same factors contribute to the transmission of these parasites. This study was conducted to investigate the parasites causing intestinal protozoal infections diagnosed in Aristide Le Dantec hospital (Senegal). Direct examination and the Ritchie technique were used. Among the 3407 stool samples studied, 645 demonstrated the presence of intestinal protozoa in single parasitism, biparasitism, or polyparasitism, representing a prevalence of 18.93%. Out of a

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4

Huang, C. M., H. C. Chen, and C. H. Zierdt. "Magainin analogs effective against pathogenic protozoa." Antimicrobial Agents and Chemotherapy 34, no. 9 (September 1, 1990): 1824–26. http://dx.doi.org/10.1128/aac.34.9.1824.

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5

de Souza, Wanderley. "Special organelles of some pathogenic protozoa." Parasitology Research 88, no. 12 (December 1, 2002): 1013–25. http://dx.doi.org/10.1007/s00436-002-0696-2.

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6

Reyes-López, Magda, Gerardo Ramírez-Rico, Jesús Serrano-Luna, and Mireya de la Garza. "Activity of Apo-Lactoferrin on Pathogenic Protozoa." Pharmaceutics 14, no. 8 (August 15, 2022): 1702. http://dx.doi.org/10.3390/pharmaceutics14081702.

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Parasites and other eventually pathogenic organisms require the ability to adapt to different environmental conditions inside the host to assure survival. Some host proteins have evolved as defense constituents, such as lactoferrin (Lf), which is part of the innate immune system. Lf in its iron-free form (apo-Lf) and its peptides obtained by cleavage with pepsin are microbicides. Parasites confront Lf in mucosae and blood. In this work, the activity of Lf against pathogenic and opportunistic parasites such as Cryptosporidium spp., Eimeria spp., Entamoeba histolytica, Giardia duodenalis, Leishm

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7

Upcroft, Peter. "Multiple drug resistance in the pathogenic protozoa." Acta Tropica 56, no. 2-3 (March 1994): 195–212. http://dx.doi.org/10.1016/0001-706x(94)90063-9.

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8

Hall, B. Fenton. "Introduction: Host cell interactions of pathogenic protozoa." Seminars in Cell Biology 4, no. 5 (October 1993): 295–96. http://dx.doi.org/10.1006/scel.1993.1035.

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9

Dudlová, Adriána, Pavol Jarčuška, Silvia Jurišová, Zuzana Vasilková, Vladimír Krčméry, and Peter Juriš. "Prevalence of non-pathogenic types of gastrointestinal protozoa in population in Slovakia and their potential importance in the aspect of public health." Acta Parasitologica 63, no. 4 (December 19, 2018): 819–25. http://dx.doi.org/10.1515/ap-2018-0100.

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Abstract The aim of the research was to determine the prevalence of non-pathogenic protozoa circulating in the human population of Slovakia. We particularly focused on the socially deprived areas with poor sanitation conditions, as they are one of the factors affecting the transmission of these infections. Within this study, 2760 people were coprologically screened for the presence of protozoan cysts. The analyzed group comprised 1173 men and 1587 women from different regions of Slovakia. The total prevalence (2.03%) of non-pathogenic protozoa species was determined. The prevalence of Entamoeb

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10

Wiser, Mark F. "Unique Endomembrane Systems and Virulence in Pathogenic Protozoa." Life 11, no. 8 (August 12, 2021): 822. http://dx.doi.org/10.3390/life11080822.

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Virulence in pathogenic protozoa is often tied to secretory processes such as the expression of adhesins on parasite surfaces or the secretion of proteases to assisted in tissue invasion and other proteins to avoid the immune system. This review is a broad overview of the endomembrane systems of pathogenic protozoa with a focus on Giardia, Trichomonas, Entamoeba, kinetoplastids, and apicomplexans. The focus is on unique features of these protozoa and how these features relate to virulence. In general, the basic elements of the endocytic and exocytic pathways are present in all protozoa. Some o

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11

Laskowski-Arce, Michelle A., and Kim Orth. "Acanthamoeba castellanii Promotes the Survival of Vibrio parahaemolyticus." Applied and Environmental Microbiology 74, no. 23 (October 10, 2008): 7183–88. http://dx.doi.org/10.1128/aem.01332-08.

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ABSTRACT Vibrio parahaemolyticus is a food-borne pathogen that naturally inhabits both marine and estuarine environments. Free-living protozoa exist in similar aquatic environments and function to control bacterial numbers by grazing on free-living bacteria. Protozoa also play an important role in the survival and spread of some pathogenic species of bacteria. We investigated the interaction between the protozoan Acanthamoeba castellanii and the bacterium Vibrio parahaemolyticus. We found that Acanthamoeba castellanii does not prey on Vibrio parahaemolyticus but instead secretes a factor that

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12

Brown, M. "Unexplored reservoirs of pathogenic bacteria: protozoa and biofilms." Trends in Microbiology 7, no. 1 (January 1, 1999): 46–50. http://dx.doi.org/10.1016/s0966-842x(98)01425-5.

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13

Crabb, Brendan S. "Recent insights into virulence determinants of pathogenic protozoa." Current Opinion in Microbiology 9, no. 4 (August 2006): 365–66. http://dx.doi.org/10.1016/j.mib.2006.06.020.

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14

BENCHIMOL, M., B. KACHAR, and W. DESOUZA. "Quick-freeze, deep visualization of the pathogenic protozoa." Cell Biology International Reports 14 (September 1990): 253. http://dx.doi.org/10.1016/0309-1651(90)91111-g.

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15

Yang, Jin-Lei, Danyang Li, and Xiao-Yong Zhan. "Concept about the Virulence Factor of Legionella." Microorganisms 11, no. 1 (December 27, 2022): 74. http://dx.doi.org/10.3390/microorganisms11010074.

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Pathogenic species of Legionella can infect human alveolar macrophages through Legionella-containing aerosols to cause a disease called Legionellosis, which has two forms: a flu-like Pontiac fever and severe pneumonia named Legionnaires’ disease (LD). Legionella is an opportunistic pathogen that frequently presents in aquatic environments as a biofilm or protozoa parasite. Long-term interaction and extensive co-evolution with various genera of amoebae render Legionellae pathogenic to infect humans and also generate virulence differentiation and heterogeneity. Conventionally, the proteins invol

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16

Agbedanu, P., No author No author, M. Brewer, No author No author, T. Day, M. Kimber, K. Anderson, S. Rasmussen, and M. Carlson. "Involvement of a putative intercellular signal-recognizing G protein-coupled receptor in the engulfment of Salmonella by the protozoan Tetrahymena." Open Veterinary Journal 5, no. 2 (2013): 69. http://dx.doi.org/10.5455/ovj.2013.v3.i2.p69.

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In an effort to investigate the molecular basis of protozoa engulfment-mediated hypervirulence of Salmonella in cattle, we evaluated protozoan G protein-coupled receptors (GPCRs) as transducers of Salmonella engulfment by the model protozoan Tetrahymena. Our laboratory previously demonstrated that non-pathogenic protozoa (including Tetrahymena) engulf Salmonella and then exacerbate its virulence in cattle, but the mechanistic details of the phenomenon are not fully understood. GPCRs were investigated since these receptors facilitate phagocytosis of particulates by Tetrahymena, and a GPCR appar

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17

Shanan, Salah, Hadi Abd, Magdi Bayoumi, Amir Saeed, and Gunnar Sandström. "Prevalence of Protozoa Species in Drinking and Environmental Water Sources in Sudan." BioMed Research International 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/345619.

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Protozoa are eukaryotic cells distributed worldwide in nature and are receiving increasing attention as reservoirs and potential vectors for the transmission of pathogenic bacteria. In the environment, on the other hand, many genera of the protozoa are human and animal pathogens. Only limited information is available on these organisms in developing countries and so far no information on their presence is available from Sudan. It is necessary to establish a molecular identification of species of the protozoa from drinking and environmental water. 600 water samples were collected from five stat

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18

Dumètre, Aurélien, Dominique Aubert, Pierre-Henri Puech, Jeanne Hohweyer, Nadine Azas, and Isabelle Villena. "Interaction Forces Drive the Environmental Transmission of Pathogenic Protozoa." Applied and Environmental Microbiology 78, no. 4 (December 9, 2011): 905–12. http://dx.doi.org/10.1128/aem.06488-11.

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ABSTRACTThe protozoan parasitesGiardia duodenalis,Cryptosporidiumspp., andToxoplasma gondiiare pathogens that are resistant to a number of environmental factors and pose significant risks to public health worldwide. Their environmental transmission is closely governed by the physicochemical properties of their cysts (Giardia) and oocysts (CryptosporidiumandToxoplasma), allowing their transport, retention, and survival for months in water, soil, vegetables, and mollusks, which are the main reservoirs for human infection. Importantly, the cyst/oocyst wall plays a key role in that regard by exhib

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19

Prole, David L., and Neil V. Marrion. "Identification of Putative Potassium Channel Homologues in Pathogenic Protozoa." PLoS ONE 7, no. 2 (February 21, 2012): e32264. http://dx.doi.org/10.1371/journal.pone.0032264.

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20

SMITH, A. W. "Protozoa and pathogenic bacteria: lessons learned from Legionella pneumophila." Journal of Eukaryotic Microbiology 52, no. 2 (March 2005): 27S—28S. http://dx.doi.org/10.1111/j.1550-7408.2005.05202003_2_4.x.

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21

De Souza, Wanderley. "Structural organization of the cell surface of pathogenic protozoa." Micron 26, no. 5 (January 1995): 405–30. http://dx.doi.org/10.1016/0968-4328(95)00010-0.

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22

Wiser, Mark F. "Feeding Mechanisms of Pathogenic Protozoa with a Focus on Endocytosis and the Digestive Vacuole." Parasitologia 4, no. 3 (July 1, 2024): 222–37. http://dx.doi.org/10.3390/parasitologia4030019.

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Endocytosis is a quintessential feature of eukaryotes, and the emergence of endocytosis played a major role in the origin and evolution of eukaryotes. During the early evolution of eukaryotes, phagocytosis and the digestion of prey (i.e., bacteria) combined with the endocytosis of macromolecules opened a new source of nutrients beyond osmotrophy. Pathogenic and commensal protozoa have retained endocytosis as a major mechanism of nutrient acquisition even though, in theory, nutrients could be obtained from the host through osmotrophy. Nearly all pathogenic protozoa exhibit endocytosis and have

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23

Dumetz, Franck, and Catherine Merrick. "Parasitic Protozoa: Unusual Roles for G-Quadruplexes in Early-Diverging Eukaryotes." Molecules 24, no. 7 (April 5, 2019): 1339. http://dx.doi.org/10.3390/molecules24071339.

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Guanine-quadruplex (G4) motifs, at both the DNA and RNA levels, have assumed an important place in our understanding of the biology of eukaryotes, bacteria and viruses. However, it is generally little known that their very first description, as well as the foundational work on G4s, was performed on protozoans: unicellular life forms that are often parasitic. In this review, we provide a historical perspective on the discovery of G4s, intertwined with their biological significance across the protozoan kingdom. This is a history in three parts: first, a period of discovery including the first ch

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24

Land, Kirkwood M., and Patricia J. Johnson. "Molecular basis of metronidazole resistance in pathogenic bacteria and protozoa." Drug Resistance Updates 2, no. 5 (October 1999): 289–94. http://dx.doi.org/10.1054/drup.1999.0104.

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25

Jackson, P., M. Pappas, and B. Hansen. "Fluorogenic substrate detection of viable intracellular and extracellular pathogenic protozoa." Science 227, no. 4685 (January 25, 1985): 435–38. http://dx.doi.org/10.1126/science.2578226.

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26

GIBSON, C. J., C. N. HAAS, and J. B. ROSE. "Risk assessment of waterborne protozoa: current status and future trends." Parasitology 117, no. 7 (November 1999): 205–12. http://dx.doi.org/10.1017/s0031182099004746.

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Throughout the past decade much research has been directed towards identifying the occurrence, epidemiology, and risks associated with waterborne protozoa. While outbreaks are continually documented, sporadic cases of disease associated with exposure to low levels of waterborne protozoa are of increasing concern. Current methodologies may not be sensitive enough to define these low levels of disease. However, risk assessment methods may be utilised to address these low level contamination events. The purpose of this article is to provide an introduction to microbial risk assessment for waterbo

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27

Cain, Cody C., Alexis T. Henry, Robert H. Waldo, Lester J. Casida, and Joseph O. Falkinham. "Identification and Characteristics of a NovelBurkholderia Strain with Broad-Spectrum Antimicrobial Activity." Applied and Environmental Microbiology 66, no. 9 (September 1, 2000): 4139–41. http://dx.doi.org/10.1128/aem.66.9.4139-4141.2000.

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ABSTRACT A Burkholderia strain isolated from soil is capable of inhibiting the growth of bacteria, plant-pathogenic fungi, pathogenic yeasts, and protozoa. Inhibition does not involve cell contact or the presence of living cells, suggesting that at least a substantial portion of the antimicrobial activity is due to the excretion of extracellular compounds.

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28

METFIES, KATJA, MARCO BERZANO, CHRISTIAN MAYER, PAUL ROOSKEN, CLAUDIO GUALERZI, LINDA MEDLIN, and GERARD MUYZER. "An optimized protocol for the identification of diatoms, flagellated algae and pathogenic protozoa with phylochips." Molecular Ecology Notes 7, no. 6 (November 2007): 925–36. http://dx.doi.org/10.1111/j.1471-8286.2007.01799.x.

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29

Ibañez-Escribano, Alexandra, Maria Teresa Gomez-Muñoz, Marta Mateo, Cristina Fonseca-Berzal, Esperanza Gomez-Lucia, Raquel Garcia Perez, Jose M. Alunda, and Javier Carrion. "Microbial Matryoshka: Addressing the Relationship between Pathogenic Flagellated Protozoans and Their RNA Viral Endosymbionts (Family Totiviridae)." Veterinary Sciences 11, no. 7 (July 17, 2024): 321. http://dx.doi.org/10.3390/vetsci11070321.

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Three genera of viruses of the family Totiviridae establish endosymbiotic associations with flagellated protozoa responsible for parasitic diseases of great impact in the context of One Health. Giardiavirus, Trichomonasvirus, and Leishmaniavirus infect the protozoa Giardia sp., Trichomonas vaginalis, and Leishmania sp., respectively. In the present work, we review the characteristics of the endosymbiotic relationships established, the advantages, and the consequences caused in mammalian hosts. Among the common characteristics of these double-stranded RNA viruses are that they do not integrate

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30

Hiatt, Robert A., Edward K. Markell, and Ernest Ng. "How Many Stool Examinations are Necessary to Detect Pathogenic Intestinal Protozoa?" American Journal of Tropical Medicine and Hygiene 53, no. 1 (July 1, 1995): 36–39. http://dx.doi.org/10.4269/ajtmh.1995.53.36.

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31

Miranda, Kildare, Wendell Girard-Dias, and Wanderley de Souza. "Application of Analytical Electron Tomography to the Study of Pathogenic Protozoa." Microscopy and Microanalysis 20, S3 (August 2014): 1314–15. http://dx.doi.org/10.1017/s1431927614008307.

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32

Bray, Patrick G., Michael P. Barrett, Stephen A. Ward, and Harry P. de Koning. "Pentamidine uptake and resistance in pathogenic protozoa: past, present and future." Trends in Parasitology 19, no. 5 (May 2003): 232–39. http://dx.doi.org/10.1016/s1471-4922(03)00069-2.

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33

de Koning, Harry P., Daniel J. Bridges, and Richard J. S. Burchmore. "Purine and pyrimidine transport in pathogenic protozoa: From biology to therapy." FEMS Microbiology Reviews 29, no. 5 (November 2005): 987–1020. http://dx.doi.org/10.1016/j.femsre.2005.03.004.

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34

Benchimol, Marlene, Juan C. Engel, Kevin S. W. Tan, and Wanderley de Souza. "Cell Biology of Pathogenic Protozoa and Their Interaction with Host Cells." BioMed Research International 2014 (2014): 1–2. http://dx.doi.org/10.1155/2014/143418.

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35

Campagnaro, Gustavo D., and Harry P. Koning. "Purine and pyrimidine transporters of pathogenic protozoa – conduits for therapeutic agents." Medicinal Research Reviews 40, no. 5 (March 7, 2020): 1679–714. http://dx.doi.org/10.1002/med.21667.

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36

Tishko, A. N., P. V. Rinarova, and L. N. Ryabinkina. "Endolimax nana invasion — from diagnosis to cure. A clinical case." Russian Journal for Personalized Medicine 3, no. 4 (September 22, 2023): 106–11. http://dx.doi.org/10.18705/2782-3806-2023-3-4-106-111.

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Endolimax nana, is one of the least described non-pathogenic intestinal protozoa that is distributed throughout the world. Transmission occurs by the fecal-oral route. The main clinical manifestations of human infection with this protozoan are symptoms of the gastrointestinal tract. We have described a clinical case of infection in an 8-year-old child. When conducting a coprological study, cysts of E. Nana were found and a course of treatment with metronidazole was prescribed. In the control study of stool samples, a negative result was obtained, clinical manifestations disappeared.

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Lambrecht, Ellen, Julie Baré, Natascha Chavatte, Wim Bert, Koen Sabbe, and Kurt Houf. "Protozoan Cysts Act as a Survival Niche and Protective Shelter for Foodborne Pathogenic Bacteria." Applied and Environmental Microbiology 81, no. 16 (June 12, 2015): 5604–12. http://dx.doi.org/10.1128/aem.01031-15.

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ABSTRACTThe production of cysts, an integral part of the life cycle of many free-living protozoa, allows these organisms to survive adverse environmental conditions. Given the prevalence of free-living protozoa in food-related environments, it is hypothesized that these organisms play an important yet currently underinvestigated role in the epidemiology of foodborne pathogenic bacteria. Intracystic bacterial survival is highly relevant, as this would allow bacteria to survive the stringent cleaning and disinfection measures applied in food-related environments. The present study shows that str

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38

Shemetova, Svetlana Aleksandrovna, Tatyana Vasilievna Nikeshina, Nina Vitalievna Polyanskaya, Gennadiy Leonidovich Shendo, Rudolf Sergeevich Arakelyan, Valeriya Sergeevna Korolkova, and Khedi Bekkhanovna Artsueva. "Sanitary and parasitological state of water bodies of the Astrakhan region for 2011–2020." Sanitarnyj vrač (Sanitary Doctor), no. 5 (May 1, 2021): 14–24. http://dx.doi.org/10.33920/med-08-2105-02.

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The article presents the material on the sanitary-parasitological state of water bodies of the Astrakhan region for 2011–2020. In total, during the analyzed period, laboratory studies were conducted on 77,017 samples taken from environmental objects (soil, water, flushes from solid household surfaces). The share of water samples in the structure of general sanitary and parasitological studies of the environment was 7.6 % (5858 samples), including unsatisfactory samples was 3.0 % (175 samples). The structure of positive findings in water samples was represented by 6 nosological forms of helmint

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Stevens, Jamie R., and Wendy C. Gibson. "The evolution of pathogenic trypanosomes." Cadernos de Saúde Pública 15, no. 4 (October 1999): 673–84. http://dx.doi.org/10.1590/s0102-311x1999000400002.

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In the absence of a fossil record, the evolution of protozoa has until recently largely remained a matter for speculation. However, advances in molecular methods and phylogenetic analysis are now allowing interpretation of the "history written in the genes". This review focuses on recent progress in reconstruction of trypanosome phylogeny based on molecular data from ribosomal RNA, the miniexon and protein-coding genes. Sufficient data have now been gathered to demonstrate unequivocally that trypanosomes are monophyletic; the phylogenetic trees derived can serve as a framework to reinterpret t

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40

Nikeshina, Tatyana V., Rudolf S. Arakelyan, Gennadii L. Shendo, Anna V. Kovalenko, Alexandra A. Kiseleva, and Olga A. Arakelyants. "Contamination of water bodies of Astrakhan region with helminth-protozoan infestations." Perm Medical Journal 39, no. 1 (January 15, 2022): 94–103. http://dx.doi.org/10.17816/pmj39194-103.

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Objective. To study and carry out the retrospective analysis of water contamination with helminth-protozoan infestations in Astrakhan Region for 2010-2019. Materials and methods. During the analyzed period, 80962 samples taken from environmental objects were examined. Results. The percentage of samples that did not meet sanitary and parasitological indicators was 1.2 % (951 samples). The proportion of water samples collected and examined for parasitological parameters (eggs and larvae of helminths, cysts of pathogenic intestinal protozoa and oocysts of cryptosporidia) was 7.5 % (60

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41

Radwan, Eman H., Amel Abd El Rahman Hassan, Wael M. Lotfy, Ahmed Abd El-Mawgood, and Hala M. Mashaal. "The Prevalence of Intestinal Parasite Infection in El Behara Schoolchildren." International Journal of Limnology 1, no. 1 (June 15, 2019): 33–51. http://dx.doi.org/10.14302/issn.2691-3208.ijli-19-2853.

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This study was conducted to evaluate the prevalence of intestinal parasite in schoolchildren in Damanhur, Egypt and some of its villages. The pathogenic enteric protozoa have been progressively involved in bargaining the soundness of a great many individuals, for the most part in creating nations. Mediations are being set up to control the dreariness and mortality because of these protozoan contaminations. A portion of these mediations target school going kids with regards to class based wellbeing intercession. The present examination concentrated on exploring the commonness of intestinal prot

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42

Coppellotti, Olimpia, Clara Fabris, Marina Soncin, Giulio Jori, and Laura Guidolin. "Photosensitized Inactivation of Protozoa Pathogenic Agents of Water- and Vector-Borne Diseases." Forum on Immunopathological Diseases and Therapeutics 2, no. 3 (2011): 247–54. http://dx.doi.org/10.1615/forumimmundisther.2011004382.

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Cano, Pedro, Alejandro Islas-Jácome, Ángeles Rangel-Serrano, Fernando Anaya-Velázquez, Felipe Padilla-Vaca, Elías Trujillo-Esquivel, Patricia Ponce-Noyola, Antonio Martínez-Richa, and Rocío Gámez-Montaño. "In Vitro Studies of Chromone-Tetrazoles against Pathogenic Protozoa, Bacteria, and Fungi." Molecules 20, no. 7 (July 8, 2015): 12436–49. http://dx.doi.org/10.3390/molecules200712436.

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Santos, Dilvani O., and Mécia M. Oliveira. "Effect of cAMP on macromolecule synthesis in the pathogenic protozoa Trypanosoma cruzi." Memórias do Instituto Oswaldo Cruz 83, no. 3 (September 1988): 287–92. http://dx.doi.org/10.1590/s0074-02761988000300004.

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Macromolecule synthesis of Trypanosoma cruzi in culture was monitored using radioactive tracers. Cells of different days in culture displayed a preferential incorporation of precursors as follows: 1 day for (³H)-thymidine cells; 3 days for (³H)-uridine cells, and 4 days for (³H)-leucine cells. Autoradiographic studies showed that (³H)-thymidine was incorporated in the DNA of both kinetoplast and nucleus in this order. Shifts in the intracellular content of cAMP either by addition of dibutyryl-cAMP or by stimulation of the adenylcyclase by isoproterenol, caused an inhibition in the synthesis of

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Bower, Susan M. "Artificial culture of Labyrinthuloides haliotidis (Protozoa: Labyrinthomorpha), a pathogenic parasite of abalone." Canadian Journal of Zoology 65, no. 8 (August 1, 1987): 2013–20. http://dx.doi.org/10.1139/z87-306.

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Labyrinthuloides haliotidis was isolated from infected abalone (Haliotis kamtschatkana) and successfully cultured in minimum essential medium with 10% fetal calf serum at 10 °C for at least 1 year. On transfer to sea water, some subcultures produced numerous motile biflagellate zoospores while zoospore production of other subcultures was poor. On return to minimum essential medium, zoospores transformed into rapidly dividing vegetative forms. Labyrinthuloides haliotidis was not fastidious in its nutrient requirements and vegetative forms grew well in several different liquid media, on agar con

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46

Birkholtz, Lyn-Marie, Marni Williams, Jandeli Niemand, Abraham I. Louw, Lo Persson, and Olle Heby. "Polyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilities." Biochemical Journal 438, no. 2 (August 12, 2011): 229–44. http://dx.doi.org/10.1042/bj20110362.

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New drugs are urgently needed for the treatment of tropical and subtropical parasitic diseases, such as African sleeping sickness, Chagas' disease, leishmaniasis and malaria. Enzymes in polyamine biosynthesis and thiol metabolism, as well as polyamine transporters, are potential drug targets within these organisms. In the present review, the current knowledge of unique properties of polyamine metabolism in these parasites is outlined. These properties include prozyme regulation of AdoMetDC (S-adenosylmethionine decarboxylase) activity in trypanosomatids, co-expression of ODC (ornithine decarbo

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47

de Souza, Wanderley, Celso Sant’Anna, and Narcisa L. Cunha-e-Silva. "Electron microscopy and cytochemistry analysis of the endocytic pathway of pathogenic protozoa." Progress in Histochemistry and Cytochemistry 44, no. 2 (June 2009): 67–124. http://dx.doi.org/10.1016/j.proghi.2009.01.001.

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48

Breitling, Reinhard, Susanne Klingner, Nico Callewaert, Regina Pietrucha, Anett Geyer, Gunter Ehrlich, Regina Hartung, et al. "Non-pathogenic trypanosomatid protozoa as a platform for protein research and production." Protein Expression and Purification 25, no. 2 (July 2002): 209–18. http://dx.doi.org/10.1016/s1046-5928(02)00001-3.

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49

Prole, David L., and Colin W. Taylor. "Identification and Analysis of Putative Homologues of Mechanosensitive Channels in Pathogenic Protozoa." PLoS ONE 8, no. 6 (June 13, 2013): e66068. http://dx.doi.org/10.1371/journal.pone.0066068.

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50

Beitz, Eric. "Aquaporin Water and Solute Channels from Malaria Parasites and Other Pathogenic Protozoa." ChemMedChem 1, no. 6 (June 12, 2006): 587–92. http://dx.doi.org/10.1002/cmdc.200500105.

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