Artículos de revistas sobre el tema "Protein variants"
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Gai, Nan, Therese Uniacke-Lowe, Jonathan O’Regan, Hope Faulkner y Alan L. Kelly. "Effect of Protein Genotypes on Physicochemical Properties and Protein Functionality of Bovine Milk: A Review". Foods 10, n.º 10 (11 de octubre de 2021): 2409. http://dx.doi.org/10.3390/foods10102409.
Texto completoLaddach, Anna, Joseph Chi Fung Ng y Franca Fraternali. "Pathogenic missense protein variants affect different functional pathways and proteomic features than healthy population variants". PLOS Biology 19, n.º 4 (28 de abril de 2021): e3001207. http://dx.doi.org/10.1371/journal.pbio.3001207.
Texto completoAlfaro-Chávez, Ana L., Jian-Wei Liu, Joanne L. Porter, Adrian Goldman y David L. Ollis. "Improving on nature’s shortcomings: evolving a lipase for increased lipolytic activity, expression and thermostability". Protein Engineering, Design and Selection 32, n.º 1 (enero de 2019): 13–24. http://dx.doi.org/10.1093/protein/gzz024.
Texto completoLarsen, Ole Halfdan, Alisa D. Kjaergaard, Anne-Mette Hvas y Peter H. Nissen. "Genetic Variants in the Protein S (PROS1) Gene and Protein S Deficiency in a Danish Population". TH Open 05, n.º 04 (octubre de 2021): e479-e488. http://dx.doi.org/10.1055/s-0041-1736636.
Texto completoChang, Glenn T. G., Bart H. A. Maas, Hans K. Ploos van Amstel, Pieter H. Reitsma, Rogier M. Bertina y Bonno N. Bouma. "Studies of the Interaction between Human Protein S and Human C4b-Binding Protein Using Deletion Variants of Recombinant Human Protein S". Thrombosis and Haemostasis 71, n.º 04 (1994): 461–67. http://dx.doi.org/10.1055/s-0038-1642461.
Texto completoFOLSOM, JAMES P. y JOSEPH F. FRANK. "Proteomic Analysis of a Hypochlorous Acid–Tolerant Listeria monocytogenes Cultural Variant Exhibiting Enhanced Biofilm Production". Journal of Food Protection 70, n.º 5 (1 de mayo de 2007): 1129–36. http://dx.doi.org/10.4315/0362-028x-70.5.1129.
Texto completoOverweg, Karin, Chris D. Pericone, Gerridina G. C. Verhoef, Jeffrey N. Weiser, Hugo D. Meiring, Ad P. J. M. De Jong, Ronald De Groot y Peter W. M. Hermans. "Differential Protein Expression in Phenotypic Variants of Streptococcus pneumoniae". Infection and Immunity 68, n.º 8 (1 de agosto de 2000): 4604–10. http://dx.doi.org/10.1128/iai.68.8.4604-4610.2000.
Texto completoThorne, Lucy G., Mehdi Bouhaddou, Ann-Kathrin Reuschl, Lorena Zuliani-Alvarez, Ben Polacco, Adrian Pelin, Jyoti Batra et al. "Evolution of enhanced innate immune evasion by SARS-CoV-2". Nature 602, n.º 7897 (23 de diciembre de 2021): 487–95. http://dx.doi.org/10.1038/s41586-021-04352-y.
Texto completoSoorajkumar, Anjana, Ebrahim Alakraf, Mohammed Uddin, Stefan S. Du Plessis, Alawi Alsheikh-Ali y Richard K. Kandasamy. "Computational Analysis of Short Linear Motifs in the Spike Protein of SARS-CoV-2 Variants Provides Possible Clues into the Immune Hijack and Evasion Mechanisms of Omicron Variant". International Journal of Molecular Sciences 23, n.º 15 (8 de agosto de 2022): 8822. http://dx.doi.org/10.3390/ijms23158822.
Texto completoMoghaddar, Mehrnoosh, Ramtin Radman y Ian Macreadie. "Severity, Pathogenicity and Transmissibility of Delta and Lambda Variants of SARS-CoV-2, Toxicity of Spike Protein and Possibilities for Future Prevention of COVID-19". Microorganisms 9, n.º 10 (18 de octubre de 2021): 2167. http://dx.doi.org/10.3390/microorganisms9102167.
Texto completoTang, Ziyang. "A Study on the Relationship between the 3-D Structure of Spike Proteins and Infectiousness of SARS-CoV-2 Delta Variant". Highlights in Science, Engineering and Technology 8 (17 de agosto de 2022): 169–77. http://dx.doi.org/10.54097/hset.v8i.1124.
Texto completoEppinger, Erik y Andreas Stolz. "Expansion of the substrate range of the gentisate 1,2-dioxygenase from Corynebacterium glutamicum for the conversion of monohydroxylated benzoates". Protein Engineering, Design and Selection 30, n.º 1 (15 de diciembre de 2016): 57–65. http://dx.doi.org/10.1093/protein/gzw061.
Texto completoZhang, Lujia, Ya Li, Litao Qin, Yu Wu y Bo Lei. "Autosomal Recessive Retinitis Pigmentosa Associated with Three Novel REEP6 Variants in Chinese Population". Genes 12, n.º 4 (7 de abril de 2021): 537. http://dx.doi.org/10.3390/genes12040537.
Texto completoSugano, Aki, Yutaka Takaoka, Haruyuki Kataguchi, Mika Ohta, Shigemi Kimura, Masatake Araki, Yoshitomo Morinaga y Yoshihiro Yamamoto. "SARS-CoV-2 Omicron BA.2.75 Variant May Be Much More Infective than Preexisting Variants Based on In Silico Model". Microorganisms 10, n.º 10 (21 de octubre de 2022): 2090. http://dx.doi.org/10.3390/microorganisms10102090.
Texto completoCho, Yunje, Wei Gu, Steve Wakins, Sam-Pin Lee, Tae-Rak Kim, John W. Brady y Carl A. Batt. "Thermostable variants of bovine β-lactoglobulin". "Protein Engineering, Design and Selection" 7, n.º 2 (1994): 263–83. http://dx.doi.org/10.1093/protein/7.2.263.
Texto completoDikici, E., X. Qu, L. Rowe, L. Millner, C. Logue, S. K. Deo, M. Ensor y S. Daunert. "Aequorin variants with improved bioluminescence properties". Protein Engineering Design and Selection 22, n.º 4 (10 de enero de 2009): 243–48. http://dx.doi.org/10.1093/protein/gzn083.
Texto completoLau, A. Y. y D. I. Chasman. "Functional classification of proteins and protein variants". Proceedings of the National Academy of Sciences 101, n.º 17 (15 de abril de 2004): 6576–81. http://dx.doi.org/10.1073/pnas.0305043101.
Texto completoFukuzawa, Atsushi, Daniel Koch, Sarah Grover, Martin Rees y Mathias Gautel. "When is an obscurin variant pathogenic? The impact of Arg4344Gln and Arg4444Trp variants on protein–protein interactions and protein stability". Human Molecular Genetics 30, n.º 12 (12 de enero de 2021): 1131–41. http://dx.doi.org/10.1093/hmg/ddab010.
Texto completoIqbal, Sumaiya, David Hoksza, Eduardo Pérez-Palma, Patrick May, Jakob B. Jespersen, Shehab S. Ahmed, Zaara T. Rifat et al. "MISCAST: MIssense variant to protein StruCture Analysis web SuiTe". Nucleic Acids Research 48, W1 (13 de mayo de 2020): W132—W139. http://dx.doi.org/10.1093/nar/gkaa361.
Texto completoFrancisco-Velilla, Rosario, Azman Embarc-Buh, Francisco del Caño-Ochoa, Salvador Abellan, Marçal Vilar, Sara Alvarez, Alberto Fernandez-Jaen et al. "Functional and structural deficiencies of Gemin5 variants associated with neurological disorders". Life Science Alliance 5, n.º 7 (7 de abril de 2022): e202201403. http://dx.doi.org/10.26508/lsa.202201403.
Texto completoAlfaro-Chávez, Ana L., Jian-Wei Liu, Bradley J. Stevenson, Adrian Goldman y David L. Ollis. "Evolving a lipase for hydrolysis of natural triglycerides along with enhanced tolerance towards a protease and surfactants". Protein Engineering, Design and Selection 32, n.º 3 (marzo de 2019): 129–43. http://dx.doi.org/10.1093/protein/gzz023.
Texto completoGuo, Jing, Owen J. L. Rackham, Niina Sandholm, Bing He, Anne-May Österholm, Erkka Valo, Valma Harjutsalo et al. "Whole-Genome Sequencing of Finnish Type 1 Diabetic Siblings Discordant for Kidney Disease Reveals DNA Variants associated with Diabetic Nephropathy". Journal of the American Society of Nephrology 31, n.º 2 (9 de enero de 2020): 309–23. http://dx.doi.org/10.1681/asn.2019030289.
Texto completoMitra, Kakoli, Thomas A. Steitz y Donald M. Engelman. "Rational design of `water-soluble' bacteriorhodopsin variants". Protein Engineering, Design and Selection 15, n.º 6 (junio de 2002): 485–92. http://dx.doi.org/10.1093/protein/15.6.485.
Texto completoNakagawa, Hiroshi, Ai Tamura, Kanako Wakabayashi, Kazuyuki Hoshijima, Masayuki Komada, Takashi Yoshida, Satoshi Kometani, Takayoshi Matsubara, Kenta Mikuriya y Toshihisa Ishikawa. "Ubiquitin-mediated proteasomal degradation of non-synonymous SNP variants of human ABC transporter ABCG2". Biochemical Journal 411, n.º 3 (14 de abril de 2008): 623–31. http://dx.doi.org/10.1042/bj20071229.
Texto completovan Wijk, Stan W., Wei Su, Leonoor F. J. M. Wijdeveld, Kennedy S. Ramos y Bianca J. J. M. Brundel. "Cytoskeletal Protein Variants Driving Atrial Fibrillation: Potential Mechanisms of Action". Cells 11, n.º 3 (25 de enero de 2022): 416. http://dx.doi.org/10.3390/cells11030416.
Texto completoGhosh, Asish Kumar, Marco Kaiser, Md Maruf Ahmed Molla, Tasnim Nafisa, Mahmuda Yeasmin, Rifat Hossain Ratul, Md Mohiuddin Sharif et al. "Molecular and Serological Characterization of the SARS-CoV-2 Delta Variant in Bangladesh in 2021". Viruses 13, n.º 11 (19 de noviembre de 2021): 2310. http://dx.doi.org/10.3390/v13112310.
Texto completovon Bülow, Sören, Mateusz Sikora, Florian E. C. Blanc, Roberto Covino y Gerhard Hummer. "Antibody accessibility determines location of spike surface mutations in SARS-CoV-2 variants". PLOS Computational Biology 19, n.º 1 (24 de enero de 2023): e1010822. http://dx.doi.org/10.1371/journal.pcbi.1010822.
Texto completoCagiada, Matteo, Kristoffer E. Johansson, Audrone Valanciute, Sofie V. Nielsen, Rasmus Hartmann-Petersen, Jun J. Yang, Douglas M. Fowler, Amelie Stein y Kresten Lindorff-Larsen. "Understanding the Origins of Loss of Protein Function by Analyzing the Effects of Thousands of Variants on Activity and Abundance". Molecular Biology and Evolution 38, n.º 8 (29 de marzo de 2021): 3235–46. http://dx.doi.org/10.1093/molbev/msab095.
Texto completoChang, Glenn T. G., Leonie Aaldering, Tilman M. Hackeng, Pieter H. Reitsma, Rogier M. Bertina y Bonno N. Bouma. "Construction and Characterization of Thrombin-resistant Variants of Recombinant Human Protein S". Thrombosis and Haemostasis 72, n.º 05 (1994): 693–97. http://dx.doi.org/10.1055/s-0038-1648944.
Texto completoSoldatenkova, A. V., A. M. Kudryashova, N. F. Gavrilova, I. V. Yakovleva, O. V. Borisova, V. V. Sviridov y N. A. Mikhailova. "Development of ELISA test for the quality control of Pseudomonas aeruginosa recombinant vaccine based on the hybrid recombinant protein". Medical Immunology (Russia) 22, n.º 4 (7 de agosto de 2020): 805–10. http://dx.doi.org/10.15789/1563-0625-doe-1906.
Texto completoRabaan, Ali A., Shamsah H. Al-Ahmed, Hawra Albayat, Sara Alwarthan, Mashael Alhajri, Mustafa A. Najim, Bashayer M. AlShehail et al. "Variants of SARS-CoV-2: Influences on the Vaccines’ Effectiveness and Possible Strategies to Overcome Their Consequences". Medicina 59, n.º 3 (5 de marzo de 2023): 507. http://dx.doi.org/10.3390/medicina59030507.
Texto completoJallat, S., D. Carvallo, L. H. Tessier, D. Roecklin, C. Roitsch, F. Ogushi, R. G. Crystal y M. Courtney. "Altered specificities of genetically engineered α1 antitrypsin variants". "Protein Engineering, Design and Selection" 1, n.º 1 (1986): 29–35. http://dx.doi.org/10.1093/protein/1.1.29.
Texto completoAli, Muhammad Zeeshan, Arshad Farid, Safeer Ahmad, Muhammad Muzammal, Mohammed Al Mohaini, Abdulkhaliq J. Alsalman, Maitham A. Al Hawaj et al. "In Silico Analysis Identified Putative Pathogenic Missense nsSNPs in Human SLITRK1 Gene". Genes 13, n.º 4 (11 de abril de 2022): 672. http://dx.doi.org/10.3390/genes13040672.
Texto completoBhattacharjee, Maloyjo Joyraj, Jinn-Jy Lin, Chih-Yao Chang, Yu-Ting Chiou, Tian-Neng Li, Chia-Wei Tai, Tz-Fan Shiu et al. "Identifying Primate ACE2 Variants That Confer Resistance to SARS-CoV-2". Molecular Biology and Evolution 38, n.º 7 (1 de marzo de 2021): 2715–31. http://dx.doi.org/10.1093/molbev/msab060.
Texto completoLi, Jinying, Hongen Xu, Jianfeng Sun, Yongan Tian, Danhua Liu, Yaping Qin, Huanfei Liu et al. "Missense Variant of Endoplasmic Reticulum Region of WFS1 Gene Causes Autosomal Dominant Hearing Loss without Syndromic Phenotype". BioMed Research International 2021 (4 de marzo de 2021): 1–9. http://dx.doi.org/10.1155/2021/6624744.
Texto completoStickler, Marcia, Anita Reddy, Joanna M. Xiong, Melanie H. Wong, Yoshiko Akamatsu, Paul R. Hinton y Fiona A. Harding. "Design, creation and in vitro testing of a reduced immunogenicity humanized anti-CD25 monoclonal antibody that retains functional activity". Protein Engineering, Design and Selection 32, n.º 12 (diciembre de 2019): 543–54. http://dx.doi.org/10.1093/protein/gzaa017.
Texto completoShah, Shrijal S., Herbert Lannon, Leny Dias, Jia-Yue Zhang, Seth L. Alper, Martin R. Pollak y David J. Friedman. "APOL1 Kidney Risk Variants Induce Cell Death via Mitochondrial Translocation and Opening of the Mitochondrial Permeability Transition Pore". Journal of the American Society of Nephrology 30, n.º 12 (26 de septiembre de 2019): 2355–68. http://dx.doi.org/10.1681/asn.2019020114.
Texto completoSu, Zhe, Yang Yang, Shengru Wang, Sen Zhao, Hengqiang Zhao, Xiaoxin Li, Yuchen Niu et al. "The Mutational Landscape of PTK7 in Congenital Scoliosis and Adolescent Idiopathic Scoliosis". Genes 12, n.º 11 (12 de noviembre de 2021): 1791. http://dx.doi.org/10.3390/genes12111791.
Texto completoRak, Alexandra, Nikolay Gorbunov, Valeria Kostevich, Alexey Sokolov, Polina Prokopenko, Larisa Rudenko y Irina Isakova-Sivak. "Assessment of Immunogenic and Antigenic Properties of Recombinant Nucleocapsid Proteins of Five SARS-CoV-2 Variants in a Mouse Model". Viruses 15, n.º 1 (13 de enero de 2023): 230. http://dx.doi.org/10.3390/v15010230.
Texto completoRamalingam, Satish, Gopalan Natarajan, Chris Schafer, Dharmalingam Subramaniam, Randal May, Ilangovan Ramachandran, Lurdes Queimado, Courtney W. Houchen y Shrikant Anant. "Novel intestinal splice variants of RNA-binding protein CUGBP2: isoform-specific effects on mitotic catastrophe". American Journal of Physiology-Gastrointestinal and Liver Physiology 294, n.º 4 (abril de 2008): G971—G981. http://dx.doi.org/10.1152/ajpgi.00540.2007.
Texto completoVermeer, Mathilde C. S. C., Daniela Andrei, Luisa Marsili, J. Peter van Tintelen, Herman H. W. Silljé, Maarten P. van den Berg, Peter van der Meer y Maria C. Bolling. "Towards a Better Understanding of Genotype–Phenotype Correlations and Therapeutic Targets for Cardiocutaneous Genes: The Importance of Functional Studies above Prediction". International Journal of Molecular Sciences 23, n.º 18 (15 de septiembre de 2022): 10765. http://dx.doi.org/10.3390/ijms231810765.
Texto completoHawkins-Hooker, Alex, Florence Depardieu, Sebastien Baur, Guillaume Couairon, Arthur Chen y David Bikard. "Generating functional protein variants with variational autoencoders". PLOS Computational Biology 17, n.º 2 (26 de febrero de 2021): e1008736. http://dx.doi.org/10.1371/journal.pcbi.1008736.
Texto completoGolub, Maksym, Virginia Guillon, Guillaume Gotthard, Dominik Zeller, Nicolas Martinez, Tilo Seydel, Michael M. Koza et al. "Dynamics of a family of cyan fluorescent proteins probed by incoherent neutron scattering". Journal of The Royal Society Interface 16, n.º 152 (marzo de 2019): 20180848. http://dx.doi.org/10.1098/rsif.2018.0848.
Texto completoLezzerini, Marco, Marianna Penzo, Marie-Françoise O’Donohue, Carolina Marques dos Santos Vieira, Manon Saby, Hyung L. Elfrink, Illja J. Diets et al. "Ribosomal protein gene RPL9 variants can differentially impair ribosome function and cellular metabolism". Nucleic Acids Research 48, n.º 2 (4 de diciembre de 2019): 770–87. http://dx.doi.org/10.1093/nar/gkz1042.
Texto completoTaylor, Susan S., Maximilian Wallbott, Erik M. F. Machal, Kristoffer Søberg, Faihaa Ahmed, Jessica Bruystens, Lily Vu et al. "PKA Cβ: a forgotten catalytic subunit of cAMP-dependent protein kinase opens new windows for PKA signaling and disease pathologies". Biochemical Journal 478, n.º 11 (11 de junio de 2021): 2101–19. http://dx.doi.org/10.1042/bcj20200867.
Texto completoMatsuura, Yuichi, Yukinobu Tohya, Masami Mochizuki, Kozo Takase y Takaaki Sugimura. "Identification of conformational neutralizing epitopes on the capsid protein of canine calicivirus". Journal of General Virology 82, n.º 7 (1 de julio de 2001): 1695–702. http://dx.doi.org/10.1099/0022-1317-82-7-1695.
Texto completoMangrolia, Parth, Dennis T. Yang y Regina M. Murphy. "Transthyretin variants with improved inhibition of β-amyloid aggregation". Protein Engineering Design and Selection 29, n.º 6 (19 de abril de 2016): 209–18. http://dx.doi.org/10.1093/protein/gzw008.
Texto completoNicora, Giovanna, Marco Salemi, Simone Marini y Riccardo Bellazzi. "Predicting emerging SARS-CoV-2 variants of concern through a One Class dynamic anomaly detection algorithm". BMJ Health & Care Informatics Online 29, n.º 1 (diciembre de 2022): e100643. http://dx.doi.org/10.1136/bmjhci-2022-100643.
Texto completoBian, Xinchao, Guangying Cheng, Xinbo Sun, Hongkun Liu, Xiangmao Zhang, Yu Han, Bo Li y Ning Li. "Two novel truncating variants in UBAP1 are responsible for hereditary spastic paraplegia". PLOS ONE 16, n.º 6 (30 de junio de 2021): e0253871. http://dx.doi.org/10.1371/journal.pone.0253871.
Texto completoFrench, Dorothy M., Terry F. McElwain, Travis C. McGuire y Guy H. Palmer. "Expression of Anaplasma marginale Major Surface Protein 2 Variants during Persistent Cyclic Rickettsemia". Infection and Immunity 66, n.º 3 (1 de marzo de 1998): 1200–1207. http://dx.doi.org/10.1128/iai.66.3.1200-1207.1998.
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