Literatura académica sobre el tema "Protein targeted lead molecule"
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Artículos de revistas sobre el tema "Protein targeted lead molecule"
Hyun, Soonsil y Dongyun Shin. "Chemical-Mediated Targeted Protein Degradation in Neurodegenerative Diseases". Life 11, n.º 7 (24 de junio de 2021): 607. http://dx.doi.org/10.3390/life11070607.
Texto completoGiardina, Sarah F., Elena Valdambrini, Michael Peel, Manny D. Bacolod, Mace L. Rothenberg, Richard B. Lanman, J. David Warren y Francis Barany. "Cure-PROs: Next-generation targeted protein degraders." Journal of Clinical Oncology 41, n.º 16_suppl (1 de junio de 2023): e15101-e15101. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e15101.
Texto completoMusielak, Bogdan, Weronika Janczyk, Ismael Rodriguez, Jacek Plewka, Dominik Sala, Katarzyna Magiera-Mularz y Tad Holak. "Competition NMR for Detection of Hit/Lead Inhibitors of Protein–Protein Interactions". Molecules 25, n.º 13 (1 de julio de 2020): 3017. http://dx.doi.org/10.3390/molecules25133017.
Texto completoThomas, Bedwyr ab Ion, H. Lois Lewis, D. Heulyn Jones y Simon E. Ward. "Central Nervous System Targeted Protein Degraders". Biomolecules 13, n.º 8 (25 de julio de 2023): 1164. http://dx.doi.org/10.3390/biom13081164.
Texto completoDas, Debanu, Matthew Duncton, Patricia Pellicena, Ashley Deacon, David Wilson y Millie Georgiadis. "Development of a DNA damage response (DDR) therapeutics platform for oncology." Journal of Clinical Oncology 39, n.º 15_suppl (20 de mayo de 2021): e15036-e15036. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e15036.
Texto completoMilosevic, Ivana. "Resistance to targeted therapy in chronic lymphocytic leukemia". Medical review 75, Suppl. 1 (2022): 57–61. http://dx.doi.org/10.2298/mpns22s1057m.
Texto completoQokoyi, Ndibonani Kebonang, Priscilla Masamba y Abidemi Paul Kappo. "Proteins as Targets in Anti-Schistosomal Drug Discovery and Vaccine Development". Vaccines 9, n.º 7 (8 de julio de 2021): 762. http://dx.doi.org/10.3390/vaccines9070762.
Texto completoOlsen, Sarah Naomi, Laura Godfrey, James P. Healy, Charles Hatton y Scott A. Armstrong. "Abstract 681: Targeted MLL-AF9 degradation is phenocopied by combined DOT1L and Menin inhibition". Cancer Research 82, n.º 12_Supplement (15 de junio de 2022): 681. http://dx.doi.org/10.1158/1538-7445.am2022-681.
Texto completoKhattri, Ram B., Daniel L. Morris, Stephanie M. Bilinovich, Erendra Manandhar, Kahlilah R. Napper, Jacob W. Sweet, David A. Modarelli y Thomas C. Leeper. "Identifying Ortholog Selective Fragment Molecules for Bacterial Glutaredoxins by NMR and Affinity Enhancement by Modification with an Acrylamide Warhead". Molecules 25, n.º 1 (30 de diciembre de 2019): 147. http://dx.doi.org/10.3390/molecules25010147.
Texto completoYang, Kylie, Jacek L. Kolanowski y Elizabeth J. New. "Mitochondrially targeted fluorescent redox sensors". Interface Focus 7, n.º 2 (6 de abril de 2017): 20160105. http://dx.doi.org/10.1098/rsfs.2016.0105.
Texto completoTesis sobre el tema "Protein targeted lead molecule"
Nilsson, Jonas. "Design, Synthesis and Characterization of Small Molecule Inhibitors and Small Molecule : Peptide Conjugates as Protein Actors". Doctoral thesis, Linköpings universitet, Organisk Kemi, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-3943.
Texto completoNacheva, Katya Pavlova. "Development of a Bio-Molecular Fluorescent Probe Used in Kinetic Target-Guided Synthesis for the Identification of Inhibitors of Enzymatic and Protein-Protein Interaction Targets". Scholar Commons, 2012. http://scholarcommons.usf.edu/etd/4376.
Texto completoVerow, Mark. "The development and validation of small molecule inhibitors targeted against the HIV-l Nef protein". Thesis, University of Leeds, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.659183.
Texto completoOmar, Hany Ahmed Mostafa Mohamed. "Molecular Pharmacology and Preclinical Studies of Novel Small-molecule Targeted Agents for The Treatment of Hepatocellular Carcinoma". The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1290565602.
Texto completoFarrington, Caroline Cain. "TARGETED DEGRADATION OF THE MYC ONCOGENE USING PP2AB56ALPHASELECTIVE SMALL MOLECULE MODULATORS OF PROTEINPHOSPHATASE 2A AS A THERAPEUTIC STRATEGY FOR TREATING MYCDRIVENCANCERS". Case Western Reserve University School of Graduate Studies / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1579905487094187.
Texto completoLu, Felice. "Protein inhibition by targeted small molecule libraries /". 2005. http://wwwlib.umi.com/dissertations/search.
Texto completoMatos, Ana Marta de Jesus Gomes de. "From a multitarget antidiabetic glycosyl isoflavone towards new molecular entities against diabetes and Alzheimer’s disease : generation of lead series and target assessment". Doctoral thesis, 2018. http://hdl.handle.net/10451/42532.
Texto completoBhowmick, Tuhin. "Crystal Structure Of Mycobacterium Tuberculosis Histone Like Protein HU And Structure Based Design Of Molecules To Inhibit MtbHU-DNA Interaction : Leads For A New Target. Structure Aided Computational Analysis Of Metal Coordinated Complexes Containing Amino Acids And Organic Moieties Designed For Photo Induced DNA Cleavage". Thesis, 2012. http://hdl.handle.net/2005/2469.
Texto completoLibros sobre el tema "Protein targeted lead molecule"
Cui, Zhao, Neil Turner y Ming-hui Zhao. Alport post-transplant antiglomerular basement membrane disease. Editado por Neil Turner. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0075.
Texto completoColbert, Robert A. y Paul Bowness. Immune mechanisms: HLA-B27. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198734444.003.0006.
Texto completoMalcangio, Marzia. Glia. Editado por Paul Farquhar-Smith, Pierre Beaulieu y Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0035.
Texto completoBeattie, R. Mark, Anil Dhawan y John W.L. Puntis. The pancreas. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198569862.003.0046.
Texto completoGropman, Andrea L., Belen Pappa y Nicholas Ah Mew. The Urea Cycle Disorders. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0063.
Texto completoCapítulos de libros sobre el tema "Protein targeted lead molecule"
Weber, L. "Discovery of New MCRs, Chemical Evolution and Lead Optimization". En Small Molecule — Protein Interactions, 189–99. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-662-05314-0_12.
Texto completoWhitty, Adrian. "Small-Molecule Inhibitors of Protein-Protein Interactions: Challenges and Prospects". En Gene Family Targeted Molecular Design, 199–233. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470423936.ch7.
Texto completoUrsu, Andrei, Matthew G. Costales, Jessica L. Childs-Disney y Matthew D. Disney. "Chapter 15. Small-molecule Targeted Degradation of RNA". En Protein Degradation with New Chemical Modalities, 317–36. Cambridge: Royal Society of Chemistry, 2020. http://dx.doi.org/10.1039/9781839160691-00317.
Texto completoPrakash, Om y Feroz Khan. "CoSSDb: A Database of Co-crystallized Ligand Sub-structures for Anticancer Lead Designing & Optimization". En Proceedings of the Conference BioSangam 2022: Emerging Trends in Biotechnology (BIOSANGAM 2022), 133–41. Dordrecht: Atlantis Press International BV, 2022. http://dx.doi.org/10.2991/978-94-6463-020-6_14.
Texto completoSharma, Sahil y Cynthia M. Sharma. "Identification of RNA Binding Partners of CRISPR-Cas Proteins in Prokaryotes Using RIP-Seq". En Methods in Molecular Biology, 111–33. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1851-6_6.
Texto completoJayaraj, Abhilash, Ruchika Bhat, Amita Pathak, Manpreet Singh y B. Jayaram. "Development of a Web-Server for Identification of Common Lead Molecules for Multiple Protein Targets". En Methods in Pharmacology and Toxicology, 487–504. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/7653_2018_9.
Texto completoTakaoka, Yousuke y Minoru Ueda. "Enantiodifferential Approach for the Target Protein Detection of the Jasmonate Glucoside That Controls the Leaf Closure of Samanea saman". En Methods in Molecular Biology, 149–58. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7874-8_13.
Texto completoRamos, Kenneth S., Stefano Guerra y Randa El-Zein. "Precision Medicine Approaches for Stratification and Development of Novel Therapies of Latin(x) Patients at Risk of Lung Malignancy". En Advancing the Science of Cancer in Latinos, 89–98. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-14436-3_8.
Texto completoDas, Amit y Simanti Bhattacharya. "Different Types of Molecular Docking Based on Variations of Interacting Molecules". En Pharmaceutical Sciences, 795–819. IGI Global, 2017. http://dx.doi.org/10.4018/978-1-5225-1762-7.ch031.
Texto completoDas, Amit y Simanti Bhattacharya. "Different Types of Molecular Docking Based on Variations of Interacting Molecules". En Methods and Algorithms for Molecular Docking-Based Drug Design and Discovery, 148–72. IGI Global, 2016. http://dx.doi.org/10.4018/978-1-5225-0115-2.ch006.
Texto completoActas de conferencias sobre el tema "Protein targeted lead molecule"
Quertermous, T., J. M. Schnee, M. S. Runge, G. R. Matsueda, N. W. Hudson, J. G. Seidman y E. Haber. "EXPRESSION OF A RECOMBINANT ANTIBODY-TARGETED THROMBOLYTIC MOLECULE". En XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644616.
Texto completoTurchi, John, Katherine S. Pawelczak, Navnath Gavande y Pamela S. VanderVere-Carozza. "Abstract A095: Targeting protein-DNA interactions in the DNA damage response: Lead identification and optimization for novel inhibitors of RPA and Ku". En Abstracts: AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics; October 26-30, 2019; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1535-7163.targ-19-a095.
Texto completoChen, Kok Hao y Jong Hyun Choi. "DNA Oligonucleotide-Templated Nanocrystals: Synthesis and Novel Label-Free Protein Detection". En ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-11958.
Texto completoSarkar, Saugata y Marissa Nichole Rylander. "Treatment Planning Model for Nanotube-Mediated Laser Cancer Therapy". En ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192997.
Texto completoTavousi, Pouya, Morad Behandish, Kazem Kazerounian y Horea T. Ilieş. "An Improved Free Energy Formulation and Implementation for Kinetostatic Protein Folding Simulation". En ASME 2013 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/detc2013-12671.
Texto completoHussein, Ola, Feras Alali, Ala‐Eddin Al Mustafa y Ashraf Khalil. "Development of Novel Chalcone Analogs as Potential Multi-Targeted Therapies for Castration-Resistant Prostate Cancer". En Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2021. http://dx.doi.org/10.29117/quarfe.2021.0114.
Texto completoVieira, Daniella Serafin Couto, Laura Otto Walter, Ana Carolina Rabello de Moraes, João Péricles da Silva Jr y Maria Cláudia Santos Silva. "CROSS-SECTIONAL ANALYSIS OF CLINICAL AND MORPHOLOGICAL FACTORS OF BREAST CANCER IMMUNOPHENOTYPES: A COMPARATIVE STUDY OF TWO DIFFERENT METHODOLOGIES OVER A 24‑YEAR HISTORICAL SERIES". En Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1043.
Texto completoBrewer, Bryson M., Yandong Gao, Rebecca M. Sappington y Deyu Li. "Microfluidic Molecular Trap: Probing Extracellular Signaling by Selectively Blocking Exchange of Specific Molecules in Cell-Cell Interactions". En ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-64489.
Texto completoHussein, Ola, Feras Alali, Ala-Eddin Al Moustafa y Ashraf Khalil. "Design, Synthesis and Biological Evaluation of Novel Chalcone Analogs as Potential Therapeutic Agents for Castration-Resistant Prostate Cancer". En Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0179.
Texto completoImai, Yohsuke, Hitoshi Kondo, Young Ho Kang, Takuji Ishikawa, Chwee Teck Lim y Takami Yamaguchi. "A Numerical Model of Adhesion Property of Malaria Infected Red Blood Cells in Micro Scale Blood Flows". En ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206456.
Texto completoInformes sobre el tema "Protein targeted lead molecule"
Gafni, Yedidya y Vitaly Citovsky. Molecular interactions of TYLCV capsid protein during assembly of viral particles. United States Department of Agriculture, abril de 2007. http://dx.doi.org/10.32747/2007.7587233.bard.
Texto completoTzfira, Tzvi, Michael Elbaum y Sharon Wolf. DNA transfer by Agrobacterium: a cooperative interaction of ssDNA, virulence proteins, and plant host factors. United States Department of Agriculture, diciembre de 2005. http://dx.doi.org/10.32747/2005.7695881.bard.
Texto completoLapidot, Moshe y Vitaly Citovsky. molecular mechanism for the Tomato yellow leaf curl virus resistance at the ty-5 locus. United States Department of Agriculture, enero de 2016. http://dx.doi.org/10.32747/2016.7604274.bard.
Texto completoOhad, Nir y Robert Fischer. Regulation of Fertilization-Independent Endosperm Development by Polycomb Proteins. United States Department of Agriculture, enero de 2004. http://dx.doi.org/10.32747/2004.7695869.bard.
Texto completoWilson, Thomas E., Avraham A. Levy y Tzvi Tzfira. Controlling Early Stages of DNA Repair for Gene-targeting Enhancement in Plants. United States Department of Agriculture, marzo de 2012. http://dx.doi.org/10.32747/2012.7697124.bard.
Texto completoCitovsky, Vitaly y Yedidya Gafni. Suppression of RNA Silencing by TYLCV During Viral Infection. United States Department of Agriculture, diciembre de 2009. http://dx.doi.org/10.32747/2009.7592126.bard.
Texto completoMeir, Shimon, Michael S. Reid, Cai-Zhong Jiang, Amnon Lers y Sonia Philosoph-Hadas. Molecular Studies of Postharvest Leaf and Flower Senescence. United States Department of Agriculture, enero de 2011. http://dx.doi.org/10.32747/2011.7592657.bard.
Texto completoGafni, Yedidya y Vitaly Citovsky. Inactivation of SGS3 as Molecular Basis for RNA Silencing Suppression by TYLCV V2. United States Department of Agriculture, noviembre de 2013. http://dx.doi.org/10.32747/2013.7593402.bard.
Texto completoTucker, Mark L., Shimon Meir, Amnon Lers, Sonia Philosoph-Hadas y Cai-Zhong Jiang. Elucidation of signaling pathways that regulate ethylene-induced leaf and flower abscission of agriculturally important plants. United States Department of Agriculture, enero de 2012. http://dx.doi.org/10.32747/2012.7597929.bard.
Texto completoGafni, Yedidya, Moshe Lapidot y Vitaly Citovsky. Dual role of the TYLCV protein V2 in suppressing the host plant defense. United States Department of Agriculture, enero de 2013. http://dx.doi.org/10.32747/2013.7597935.bard.
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