Artículos de revistas sobre el tema "Programmed art"

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1

O’Rourke, Karen. "From Networked Art to Programmed Drifts: “Art as Experience” Today". Leonardo 48, n.º 5 (octubre de 2015): 480. http://dx.doi.org/10.1162/leon_a_01112.

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King, Mike. "Programmed Graphics in Computer Art and Animation". Leonardo 28, n.º 2 (1995): 113. http://dx.doi.org/10.2307/1576132.

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Stefanski, Ana‐Luisa, Annika Wiedemann, Karin Reiter, Falk Hiepe, Andreia C. Lino y Thomas Dörner. "Enhanced Programmed Death 1 and Diminished Programmed Death Ligand 1 Up‐Regulation Capacity of Post‐Activated Lupus B Cells". Arthritis & Rheumatology 71, n.º 9 (6 de agosto de 2019): 1539–44. http://dx.doi.org/10.1002/art.40897.

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Bertsias, George K., Magda Nakou, Christianna Choulaki, Amalia Raptopoulou, Eva Papadimitraki, George Goulielmos, Herakles Kritikos et al. "Genetic, immunologic, and immunohistochemical analysis of the programmed death 1/programmed death ligand 1 pathway in human systemic lupus erythematosus". Arthritis & Rheumatism 60, n.º 1 (enero de 2009): 207–18. http://dx.doi.org/10.1002/art.24227.

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5

Fukasawa, Takemichi, Ayumi Yoshizaki, Satoshi Ebata, Kouki Nakamura, Ryosuke Saigusa, Syunsuke Miura, Takashi Yamashita et al. "Contribution of Soluble Forms of Programmed Death 1 and Programmed Death Ligand 2 to Disease Severity and Progression in Systemic Sclerosis". Arthritis & Rheumatology 69, n.º 9 (agosto de 2017): 1879–90. http://dx.doi.org/10.1002/art.40164.

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de Velasco, Guillermo, Boonie Bermas y Toni K. Choueiri. "Autoimmune Arthropathy and Uveitis as Complications of Programmed Death 1 Inhibitor Treatment". Arthritis & Rheumatology 68, n.º 2 (25 de enero de 2016): 556–57. http://dx.doi.org/10.1002/art.39406.

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7

Bolognini, Maurizio. "Globalization, art and the art system". Ekistics and The New Habitat 73, n.º 436-441 (1 de diciembre de 2006): 191–95. http://dx.doi.org/10.53910/26531313-e200673436-441115.

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The author's research interests are: art, technology and democracy. On this latter subject he has published several essays and a book entitled Democrazia elettronica (Carocci, Rome, 2001). As an artist he has worked with digital technologies since the 1980s. One of his best-known works is Computer sigillati (Sealed Computers, 1992): more than 200 machines which are programmed to produce flows of random images and then left to work indefinitely, usually without monitors. His works have been exhibited widely in Europe and the USA. He has put on shows, presentations and performances in Paris, New York , Los Angeles, San Francisco, Sydney. His latest one-man shows include: Museo Laboratorio di Arte Contemporanea (Rome, 2003), WilliamsburgArt& Historical Center (New York, 2003), Museo di Arte ContemporaneaVilla Croce (Genoa, 2005). Latest books on his work: D. Scudero (ed.),Maurizio Bolognini: Installazioni, disegni, azioni (on/off line), (Lithos,2003); and S. Solimano (ed.), Maurizio Bolognini: Infinity out of Control(Neos, 2005). The text that follows was made available to the participants of the international symposion on "Globalization and Local Identity, " organized jointly by the World Society for Ekistics and the University of Shiga Prefecture in Hikone, Japan, 19-24 September, 2005, which the author was finally unable to attend.
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8

Dorin, Alan. "Generative processes and the electronic arts". Organised Sound 6, n.º 1 (abril de 2001): 47–53. http://dx.doi.org/10.1017/s1355771801001078.

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This paper gives a personal perspective on the application and relevance of generative processes to art production. This view is that of a computer programmer, rather than that of a user of computer programs written (or hardware constructed) by others. The programmer is in the unique position of being able to describe and manipulate abstract processes which may be used as a unique means of artistic expression. This gives a greater amount of freedom to the programmer/artist than is the case when he or she is limited by programmed procedures defined by others.Prior to the development of a formal means of specifying visual and aural events, a concrete machine or set of rules for their manipulation and a means of bringing these representations back into the world as physical events, abstract processes were things to be contemplated but not experienced. Musical and spatial notations employed by artists, engineers and others, in concert with the programming of computing hardware, have opened the way for those who wish to manipulate processes in their artistic practice.In order to focus study and practice in the area of such generative computer art, the Center for Electronic Media Art (CEMA) has been established in Melbourne, Australia. The Center has spawned an international conference series on generative/process-based electronic art called Iteration. The perceived roles of the Center and Iteration conferences are discussed in this paper.
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9

Zhang, Kang y Jinhui Yu. "Generation of Kandinsky Art". Leonardo 49, n.º 1 (febrero de 2016): 48–54. http://dx.doi.org/10.1162/leon_a_00908.

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The authors present a programmed experiment to automatically generate art in the style of Kandinsky during his Bauhaus years. The program the authors developed analyzes the artist’s paintings based on his art theories and the authors’ own understanding and observations of his artworks. The authors describe the generation process in detail and share and discuss sample generated images styled according to four of Kandinsky’s paintings. By pseudorandomizing various parameters, the program is able to make each styled image it generates unique. The authors’ approach is highly scalable, limited only by the memory space set in the programming language Processing, which is used for the generation. Potential impacts of the authors’ approach are also discussed.
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10

Lee, Hyunjeong y Daeheon Bae. "A Study on the Protection of Generative Art". Korea Copyright Commission 140 (31 de diciembre de 2022): 257–93. http://dx.doi.org/10.30582/kdps.2022.35.4.257.

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‘Generative Art’ is a artistic work in which some or all of the work is produced using an autonomous system programmed with algorithms; it is a field of Digital Art. This art form has existed for years, but works were not properly evaluated since it is difficult to prove what is original. However, with the advent of Non-Fungible Tokens(NFTs), the original can now be verified, and thus this art form has achieved rapid growth over the last few years. This study examined whether Generative Art can be protected by the current Copyright Act. To this end, it classified Generative Art creation based on the level of contribution by human into four different types. 1)A type in which humans create works using software, 2)a type in which humans create parts and combine them with algorithms, 3)a type in which works are created with mathematical functions, and 4)a type in which works are created using Artificial Intelligence(AI). This study also sought ways to protect works created by AI, which are not protected under the current Copyright Act. In addition, it examined how to protect Generative Art by reviewing whether the exemption provisions of Online Service Providers(OSP) can be applied when a violated work is traded on an NFT platform.
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11

Ismkhan, Hassan y Kamran Zamanifar. "Developing Programming Tools to Handle Traveling Salesman Problem by the Three Object-Oriented Languages". Applied Computational Intelligence and Soft Computing 2014 (2014): 1–17. http://dx.doi.org/10.1155/2014/137928.

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The traveling salesman problem (TSP) is one of the most famous problems. Many applications and programming tools have been developed to handle TSP. However, it seems to be essential to provide easy programming tools according to state-of-the-art algorithms. Therefore, we have collected and programmed new easy tools by the three object-oriented languages. In this paper, we present ADT (abstract data type) of developed tools at first; then we analyze their performance by experiments. We also design a hybrid genetic algorithm (HGA) by developed tools. Experimental results show that the proposed HGA is comparable with the recent state-of-the-art applications.
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12

Zanelli, Magda, Valentina Fragliasso, Paola Parente, Alessandra Bisagni, Francesca Sanguedolce, Maurizio Zizzo, Giuseppe Broggi et al. "Programmed Death Ligand 1 (PD-L1) Expression in Lymphomas: State of the Art". International Journal of Molecular Sciences 25, n.º 12 (11 de junio de 2024): 6447. http://dx.doi.org/10.3390/ijms25126447.

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The interaction of programmed death-1 (PD-1) on T lymphocytes with its ligands Programmed Death Ligand 1 (PD-L1) and Programmed Death Ligand 2 (PD-L2) on tumor cells and/or tumor-associated macrophages results in inhibitory signals to the T-cell receptor pathway, consequently causing tumor immune escape. PD-L1/PD-L2 are currently used as predictive tissue biomarkers in clinical practice. Virtually PD-L1 levels expressed by tumor cells are associated with a good response to immune checkpoint blockade therapies targeting the PD-1/PD-L1 axis. These therapies restore T-cell antitumor immune response by releasing T-lymphocytes from the inhibitory effects of tumor cells. Immune checkpoint therapies have completely changed the management of patients with solid cancers. This therapeutic strategy is less used in hematological malignancies, although good results have been achieved in some settings, such as refractory/relapsed classic Hodgkin lymphoma and primary mediastinal large B-cell lymphoma. Variable results have been obtained in diffuse large B-cell lymphoma and T-cell lymphomas. Immunohistochemistry represents the main technique for assessing PD-L1 expression on tumor cells. This review aims to describe the current knowledge of PD-L1 expression in various types of lymphomas, focusing on the principal mechanisms underlying PD-L1 overexpression, its prognostic significance and practical issues concerning the evaluation of PD-L1 immunohistochemical results in lymphomas.
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13

Shargunam, S. y G. Rajakumar. "Predictive Analysis on Sensor Data Using Distributed Machine Learning". Asian Journal of Computer Science and Technology 11, n.º 1 (22 de abril de 2022): 1–4. http://dx.doi.org/10.51983/ajcst-2022.11.1.3071.

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The science of getting computers to act without being explicitly programmed is known as machine learning. Machine learning is comparable to data mining in terms of how it works. Both systems sift through data in order to find patterns. Machine learning, on the other hand, instead of extracting data for human comprehension as in data mining applications, uses that data to increase the program's own understanding. Data patterns are detected by machine learning programmes, which then alter Programme behaviours accordingly. This research is based on real-world data obtained from sensors in an oil and Gas Corporation that monitor drilling procedures and equipment. The sensor data is streamed in at a one-second period, resulting in 86400 rows of data per day. Ox data's H2O has chosen for this problem after researching state-of-the-art Big Data analytics tools such as Mahout, RHadoop, and Spark because of its rapid in-memory processing, robust machine learning engine, and ease of use. Missed values can be estimated using accurate predictive analytics of massive sensor data, or wrong readings can be replaced owing to malfunctioning sensors or a broken communication line. It can also be used to predict circumstances to aid in various decision-making processes, such as maintenance planning and operation. In this project, sensor data has been evaluated and anticipate output using the H2O tool. The machine learning techniques has been employed in distributed systems, such as connecting five nodes to accomplish parallel processing.
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14

Rosado, Pilar. "Computer Vision Models to Categorize Art Collections According to the Visual Content: A New Approach to the Abstract Art of Antoni Tàpies". Leonardo 52, n.º 3 (junio de 2019): 255–60. http://dx.doi.org/10.1162/leon_a_01443.

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This study uses computer vision models, which to some extent simulate the initial stages of human visual perception, to help categorize data in large sets of images of artworks by the artist Antoni Tàpies. The images have been analyzed on the basis of their compositional, chromatic and organizational characteristics, without textual notes, so that the analogies found may take us closer to, and help us to understand, the creator’s original values. The system as programmed can assist the specialist by establishing analogies between different artists or periods using the same criteria.
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15

Lin, Shih-Chang, Jeng-Hsien Yen, Jaw-Ji Tsai, Wen-Chen Tsai, Tsan-Teng Ou, Hong-Wen Liu y Chung-Jen Chen. "Association of a programmed death 1 gene polymorphism with the development of rheumatoid arthritis, but not systemic lupus erythematosus". Arthritis & Rheumatism 50, n.º 3 (2004): 770–75. http://dx.doi.org/10.1002/art.20040.

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16

Alarcon-Riquelme, Marta E. "Programmed death 1 gene polymorphism and systemic lupus erythematosus in different ethnic populations: Comment on the article by Lin et al". Arthritis & Rheumatism 52, n.º 1 (enero de 2005): 363. http://dx.doi.org/10.1002/art.20778.

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17

Mancuso, Rubia Isler, Sara Teresinha Olalla Saad y Juliana Hofstätter Azambuja. "Artesunate Switches Monocytes to an Inflammatory Phenotype with the Ability to Kill Leukemic Cells". International Journal of Molecular Sciences 22, n.º 2 (9 de enero de 2021): 608. http://dx.doi.org/10.3390/ijms22020608.

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Monocytes are components of the tumor microenvironment related to cancer progression and immune escape. Therapeutic strategies for reprogramming monocytes from a tumor-supporting phenotype towards a tumoricidal phenotype are of great interest. Artesunate (ART) may be an interesting option for cancer treatment; however, the role of ART in regulating the inflammatory tumor microenvironment has not yet been investigated. Our aim is to evaluate the immunomodulatory potential of ART in vitro in human primary monocytes. ART treatment induced an increase in inflammatory monocytes (CD14highCD16−) with HLA-DR high expression and MCP-1/IL-1β release. On the other hand, ART treatment reduced CD206 and CD163 expression, and abolished the monocyte population known as non-classical and intermediate. Leukemia cells in contact with monocytes programmed with ART presented enhanced in vitro apoptosis suggesting that monocytes acquired the ability to kill leukemic cells. ART induced changes in the monocyte phenotype were mediated by JAK2/STAT3 downregulation. The induction of immunosuppressive environment is an important step for cancer progression. ART showed an immunomodulatory activity, leading immune cells to an antitumor phenotype and could be a candidate for immunotherapy in cancer patients.
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18

Mancuso, Rubia Isler, Sara Teresinha Olalla Saad y Juliana Hofstätter Azambuja. "Artesunate Switches Monocytes to an Inflammatory Phenotype with the Ability to Kill Leukemic Cells". International Journal of Molecular Sciences 22, n.º 2 (9 de enero de 2021): 608. http://dx.doi.org/10.3390/ijms22020608.

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Monocytes are components of the tumor microenvironment related to cancer progression and immune escape. Therapeutic strategies for reprogramming monocytes from a tumor-supporting phenotype towards a tumoricidal phenotype are of great interest. Artesunate (ART) may be an interesting option for cancer treatment; however, the role of ART in regulating the inflammatory tumor microenvironment has not yet been investigated. Our aim is to evaluate the immunomodulatory potential of ART in vitro in human primary monocytes. ART treatment induced an increase in inflammatory monocytes (CD14highCD16−) with HLA-DR high expression and MCP-1/IL-1β release. On the other hand, ART treatment reduced CD206 and CD163 expression, and abolished the monocyte population known as non-classical and intermediate. Leukemia cells in contact with monocytes programmed with ART presented enhanced in vitro apoptosis suggesting that monocytes acquired the ability to kill leukemic cells. ART induced changes in the monocyte phenotype were mediated by JAK2/STAT3 downregulation. The induction of immunosuppressive environment is an important step for cancer progression. ART showed an immunomodulatory activity, leading immune cells to an antitumor phenotype and could be a candidate for immunotherapy in cancer patients.
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19

Amini-Adle, Mona, Muriel Piperno, Jérémie Tordo, Luc Thomas, Stéphane Dalle, Valérie Dubois y Aurélien Marabelle. "Remitting Seronegative Symmetric Synovitis With Pitting Edema Associated With Partial Melanoma Response Under Anti-CTLA-4 and Anti-Programmed Death 1 Combination Treatment". Arthritis & Rheumatology 70, n.º 8 (7 de julio de 2018): 1358. http://dx.doi.org/10.1002/art.40506.

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20

Kerr, Keith M., Ming-Sound Tsao, Andrew G. Nicholson, Yasushi Yatabe, Ignacio I. Wistuba y Fred R. Hirsch. "Programmed Death-Ligand 1 Immunohistochemistry in Lung Cancer: In what state is this art?" Journal of Thoracic Oncology 10, n.º 7 (julio de 2015): 985–89. http://dx.doi.org/10.1097/jto.0000000000000526.

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21

Bolstad, Anne Isine, Hans Geir Eiken, Benedikte Rosenlund, Marta E. Alarcón-Riquelme y Roland Jonsson. "Increased salivary gland tissue expression of Fas, Fas ligand, cytotoxic T lymphocyte–associated antigen 4, and programmed cell death 1 in primary Sjögren's syndrome". Arthritis & Rheumatism 48, n.º 1 (enero de 2003): 174–85. http://dx.doi.org/10.1002/art.10734.

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22

Hu, Yingying, Nan Guo, Ting Yang, Jianghong Yan, Wenjun Wang y Xiang Li. "The Potential Mechanisms by which Artemisinin and Its Derivatives Induce Ferroptosis in the Treatment of Cancer". Oxidative Medicine and Cellular Longevity 2022 (4 de enero de 2022): 1–12. http://dx.doi.org/10.1155/2022/1458143.

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Artemisinin (ART) is a bioactive molecule derived from the Chinese medicinal plant Artemisia annua (Asteraceae). ART and artemisinin derivatives (ARTs) have been effectively used for antimalaria treatment. The structure of ART is composed of a sesquiterpene lactone, including a peroxide internal bridge that is essential for its activity. In addition to their well-known antimalarial effects, ARTs have been shown recently to resist a wide range of tumors. The antineoplastic mechanisms of ART mainly include cell cycle inhibition, inhibition of tumor angiogenesis, DNA damage, and ferroptosis. In particular, ferroptosis is a novel nonapoptotic type of programmed cell death. However, the antitumor mechanisms of ARTs by regulating ferroptosis remain unclear. Through this review, we focus on the potential antitumor function of ARTs by acting on ferroptosis, including the regulation of iron metabolism, generation of reactive oxygen species (ROS), and activation of endoplasmic reticulum stress (ERS). This article systematically reviews the recent progress in ferroptosis research and provides a basis for ARTs as an anticancer drug in clinical practice.
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23

Xiao, Xiaoning. "The Use of Traditional Opera Elements in the Characterization Process of Contemporary Stage Drama". Highlights in Art and Design 4, n.º 1 (3 de septiembre de 2023): 13–16. http://dx.doi.org/10.54097/hiaad.v4i1.11564.

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As one of the national treasures of China, the art of opera shapes characters from various aspects such as opera music, character movements, character situations, props, etc., plus its unique programmed aesthetic characteristics, which makes the art of opera make great achievements in character shaping. Based on its own development and change requirements, coupled with the localized transformation requirements of foreign stage dramas, the stage drama has continuously absorbed the successful factors of the opera, especially in the aspect of characterization. The article takes the application of opera elements in the process of characterization of stage plays as the research object, and takes literature analysis, unity of history and logic as the research method, and takes the historical combination of the development of opera art and stage plays, the way of characterization of opera art, and the application practice of opera elements in the process of characterization of contemporary stage plays as the research content, so as to provide reference and reference for the shaping of characterization of opera art and stage plays. It provides reference for the shaping of characters in theatre art and stage drama.
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24

Kristjansdottir, Helga, Kristjan Steinsson, Iva Gunnarsson, Gerdur Gröndal, Kristjan Erlendsson y Marta E. Alarcón-Riquelme. "Lower expression levels of the programmed death 1 receptor on CD4+CD25+ T cells and correlation with the PD-1.3A genotype in patients with systemic lupus erythematosus". Arthritis & Rheumatism 62, n.º 6 (22 de febrero de 2010): 1702–11. http://dx.doi.org/10.1002/art.27417.

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Doran, Mark. "London, Barbican: Vaughan Williams rarities". Tempo 58, n.º 228 (abril de 2004): 70–73. http://dx.doi.org/10.1017/s0040298204320152.

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Film music, often considered a ‘Cinderella’ art-form, is really more of a ‘Sleeping Beauty’: to a ‘first approximation’, its entire history exists on films which we are never shown. Prefatory to the 2003 Musicians Benevolent Fund Royal Concert on 4 November, however, the Barbican cinema presented an early-evening resuscitation of no fewer than four long-dormant items connected in some way with Vaughan Williams, two of whose orchestral works were programmed to follow.
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26

Pei, Eujin. "4D Printing: dawn of an emerging technology cycle". Assembly Automation 34, n.º 4 (9 de septiembre de 2014): 310–14. http://dx.doi.org/10.1108/aa-07-2014-062.

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Purpose – The purpose of this article is to reviews state-of-the-art developments in four-dimensional (4D) printing, discuss what it is, investigate new applications that have been discovered and suggest its future impact. Design/methodology/approach – The article clarifies the definition of 4D printing and describes notable examples covering material science, equipment and applications. Findings – This article highlights an emerging technology cycle where 4D printing research has gained traction within additive manufacturing. The use of stimuli-responsive materials can be programmed and printed to enable pre-determined reactions when subject to external stimuli. Originality/value – This article reviews state-of-the-art developments in 4D printing, discusses what it is, investigates new applications that have been discovered and suggests its future impact.
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27

Morellet, Francois. "“Viewer to Viewer, or The Art of Unpacking One's Picnic” and Other Essays". October 157 (julio de 2016): 128–60. http://dx.doi.org/10.1162/octo_a_00262.

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This anthology of writings by artist François Morellet (1926–2016) presents new translations of texts, several never before published in English, that concern his early development, from the 1950s—during which he elaborated the systematic conception of art that would govern his practice throughout his life—to the 1960s, when he was a founding member of the Groupe de Recherche d'Art Visuel. With humor and clarity, Morellet details his plans for a “programmed experimental painting”; a call for active participation by viewers of contemporary art; the influence of Mondrian, van Doesburg, Max Bill, and others on his work and the ways in which he tried to eliminate choice as much as possible from his grid paintings; and, most satirically, the ways to recognized as a “serious” artist.
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Bahji, Zineb Bahji. "Ahmed Cherkaoui : Entre Modernité et Enracinement, Museum Mohammed VI for Modern and Contemporary Arts (MMVI), Rabat, Morocco, 27.03.2018 - 27.08.2018." Museum and Society 17, n.º 1 (10 de marzo de 2019): 137–40. http://dx.doi.org/10.29311/mas.v17i1.2977.

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The exhibition Ahmed Cherkaoui: Entre Modernité et Enracinement, Museum Mohammed VI for Modern and Contemporary Arts (MMVI),Rabat,Morocco, 27.03.2018 - 27.08.2018 was held in a succession of art exhibitions that Museum Mohammed VI has programmed since its creation in 2014 to preserve, promote and celebrate the national arts of Morocco. The exhibition introduced and represented the artworks of one of the iconic founders of Moroccan modern painting in post-colonial Morocco, a leading figure who experimented with material and content to create a harmonious and mystic synthesis of the traditional and the modern. Through a varied set of abstract paintings and drawings, the exhibition illustrated and interpreted Cherkaoui's works, and it narrated the life of this artist to show how his hybrid cultural experience influenced his creation. Cherkaoui's fascination with the popular signs and decorative symbols of his civilization and his passion for abstraction in modern art inspired a unique plastic vocabulary and style that marked the birth, development and history of modern art inMorocco.
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Pei, Eujin. "4D printing – revolution or fad?" Assembly Automation 34, n.º 2 (1 de abril de 2014): 123–27. http://dx.doi.org/10.1108/aa-02-2014-014.

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Purpose – This feature article aims to review state-of-the-art developments in additive manufacture, in particular, 4D printing. It discusses what it is, what research has been carried out and maps potential applications and its future impact. Design/methodology/approach – The article first defines additive manufacturing technologies and goes on to describe the state-of-the-art. Following which the paper examines several case studies and maps a trend that shows an emergence of 4D printing. Findings – The case studies highlight a particular specialization within additive manufacture where the use of adaptive, biomimetic composites can be programmed to reshape, or have embedded properties or functionality that transform themselves when subjected to external stimuli. Originality/value – This paper discusses the state-of-the-art of additive manufacture, discussing strategies that can be used to reduce the print process (such as through kinematics); and the use of smart materials where parts adapt themselves in response to the surrounding environment supporting the notion of self-assemblies.
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Muenchhoff, Maximilian, Emily Adland, Julia Roider, Henrik Kløverpris, Alasdair Leslie, Stephan Boehm, Oliver T. Keppler, Thumbi Ndung’u y Philip J. R. Goulder. "Differential Pathogen-Specific Immune Reconstitution in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Children". Journal of Infectious Diseases 219, n.º 9 (8 de enero de 2019): 1407–17. http://dx.doi.org/10.1093/infdis/jiy668.

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Abstract Background Susceptibility to coinfections in human immunodeficiency virus (HIV)-infected patients remains increased despite antiretroviral therapy (ART). To elucidate mechanisms involved in immune reconstitution, we studied immune activation, immune exhaustion, and HIV- and copathogen-specific T-cell responses in children before and after ART. Methods We prospectively enrolled 25 HIV-infected children to study HIV-, cytomegalovirus (CMV)-, and tuberculosis (TB)-specific T-cell responses before and 1 year after initiation of ART using intracellular cytokine (interleukin-2, interferon-γ, tumor necrosis factor-α) staining assays after in vitro stimulation. We further measured expression of activation, immune exhaustion, and memory phenotype markers and studied proliferative responses after antigen stimulation. Results We observed differential, pathogen-specific changes after 1 year of ART in cytokine profiles of CD4 T-cell responses that were associated with shifts in memory phenotype and decreased programmed cell death 1 (PD-1) expression. The proliferative capacity of HIV- and PPD-specific responses increased after 1 year of ART. Of note, the recovery of CMV- and TB-specific responses was correlated with a decrease in PD-1 expression (r = 0.83, P = .008 and r = 0.81, P = .0007, respectively). Conclusions Reconstitution of immune responses on ART is associated with alterations in T-cell phenotype, function, and PD-1 expression that are distinct for HIV, TB, and CMV. The PD-1 pathway represents a potential target for immunotherapy in HIV-infected patients on ART with insufficient immune reconstitution.
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31

Sundaram, Kishore Kumar Meenakshi, Giridharan Bupesh y Konda Mani Saravanan. "Instrumentals behind embryo and cancer: a platform for prospective future in cancer research". AIMS Molecular Science 9, n.º 1 (2022): 25–45. http://dx.doi.org/10.3934/molsci.2022002.

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<abstract> <p>The cancer cells could be celled biomass without normal cellular regulation. They bypass most of the signaling pathways leading to programmed cell division. On the other hand, the embryos are highly regulated, giving rise to the whole organism based on the planned regulation. Understanding the bridge concepts between them might be an interventional art for discovering valuable cancer drugs. The present review highlighted the most similarities between them and recent literary works.</p> </abstract>
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Brezgin, Sergey, Anastasiya Kostyusheva, Dmitry Kostyushev y Vladimir Chulanov. "Dead Cas Systems: Types, Principles, and Applications". International Journal of Molecular Sciences 20, n.º 23 (30 de noviembre de 2019): 6041. http://dx.doi.org/10.3390/ijms20236041.

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The gene editing tool CRISPR-Cas has become the foundation for developing numerous molecular systems used in research and, increasingly, in medical practice. In particular, Cas proteins devoid of nucleolytic activity (dead Cas proteins; dCas) can be used to deliver functional cargo to programmed sites in the genome. In this review, we describe current CRISPR systems used for developing different dCas-based molecular approaches and summarize their most significant applications. We conclude with comments on the state-of-art in the CRISPR field and future directions.
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Grebenuk, Natalia, Olena Batovska, Yana Kyrylenko, Tamara Tesler y Rafail Hasanov. "Syncretic Trends in Contemporary Western European Vocal and Choral Art: The Challenge of Today". Studia Universitatis Babeş-Bolyai Musica 66, n.º 2 (diciembre de 2021): 157–77. http://dx.doi.org/10.24193/subbmusica.2021.2.11.

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"The aspects covered in the article proved the topicality of the research, in particular the analysis of contemporary Western European vocal and choral art presented the meanings embedded in the musical work, programmed interactive dialogue in the author-performer, listeners system, clearly demonstrating its syncretic trends in the modern conditions of development. The article reveals the essential features of syncretic trends of Western European contemporary vocal and choral art, indicates their significance for society. The foregrounding of the research is aimed at activating not only the creative mastery of certain boundaries, but also the expansion of the boundaries of personal experience. The aim of the research is achieved, namely the mechanism of integrating creativity of the representatives of contemporary Western European musical art in relation to art space is revealed on the example of creativity of the Italian composer Sciarrino, Italian composer Berio, Spanish composer and pianist Simarro. A retrospective coverage of the history of musicological thought in European humanities is presented, syncretic tendencies in modern Western European vocal and choral art are identified, its discourse is proposed as a challenge to the present. The study involved the following research methods: observations and conversations. The obtained research results can be further used as a developed model of forming vocal and choral thesaurus, which is in line with the current state of music, vocal and choral culture. Analysis of the peculiarities of the current state of choral art in Western Europe in the 20th — early 21st centuries is a promising area for further research. Keywords: Choral art. Harmonisation. Musical Art. Vocal work. Artistic image. Syncretism in music. "
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Ермилова, Дарья y Darya Ermilova. "Soviet constructivism as a creative design concept of the XX century". Servis Plus 11, n.º 3 (19 de septiembre de 2017): 54–70. http://dx.doi.org/10.22412/1993-7768-11-3-7.

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The article is devoted to the theory and practice of Soviet constructivism as a creative concept in the design of the XX century in the context of the theory of "production art". Subject of research considers to be theoretical propositions, which were implemented in particular design methods and projects of industrial clothes and constructivist fabrics as an example of practical implementation of the ideas of constructivism. The aim of the study is the examination of constructivism as a creative concept in the design from the point of view of formation peculiarities of its theoretical bases and design methodologies. The hypothesis of the study is the constructivism, which arose under the influence of "industrial art" concept, among other things, suggested the active use of the graphical method of forming and methods of combinatorial programmed forming, which were due to the creative experience in the field of non-objective painting. The study uses the cultural studies approach, which considers design activity of constructivists in close connection with the realities of the era, a systematic approach that allows revealing the relationship of aesthetic theories with the concrete practice of design-design, art analysis in the description of projects of the constructivists. The article proves the influence of the theory of "industrial art" on the formation of the concept of constructivism, analyzes the origins and features of the method of constructivism, especially the graphics method of forming and methods of programmed forming. The article compares the concepts of constructivism with the trends of costume design of the XX century. There are identified the "weak points" of the concept and method of constructivism, which became one of the reasons for failing to fully implement projects in practice. For the first time there were identified the causes of failures in the design of the costume, not associated with ideological attitudes, and with the very creative method. The results of the study fill the insufficiently developed areas in the history of constructivism. Because the constructivism methods remain relevant for modern design, the results of the study can be applied in teaching of "Design" profes-sional disciplines.
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Ceaușu, Felicia. "3. Artistic Education and Creative Art-Therapy". Review of Artistic Education 26, n.º 1 (1 de marzo de 2023): 236–41. http://dx.doi.org/10.2478/rae-2023-0033.

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Abstract As for the phrase “artistic education”, in this paper work, it was used in the way of cultivating individual, authentic artistic talent, of acquiring individual skills, abilities and techniques, with the aim of training artists in different fields of arts, as well as the assimilation of theoretical and practical knowledge from the fields of theory, aesthetics, criticism and history of arts etc., adapted to natural, innate capacities with a view to non-verbal creative expression and development plastic expressiveness. Art education and art therapy have in common the fact that they are forms of applications of art that integrate theories and practices of art pedagogy in a supportive environment: museums, art galleries, ambient art - street or interior - nature, classrooms or creative studios, where artists use the influences offered by the environments specific to the practice of the arts, which by their pluri/inter/trans-disciplinary character, encourage freedom of creation, thought, expression and imagination. Being “postmodernist” in art therapy, as Shirley Riley sees it, assumes a renunciation of programmed knowledge. For the art therapist it is essential to become the “student” of the client and to “learn from each client the meaning of the situation that he brings”. Through “co-constructive” therapy with the client, the art therapist becomes a collaborator in the therapeutic activity. Art therapy, as a component of occupational therapy, aims to correct the consequences of the disease that caused the disability or handicap, the development of adaptive skills, so that a person with a certain degree of incapacity can make the most of his or her remaining potential, in order to recover (both at family and professional level), by integrating into a useful activity at the highest level accessible to him. The therapeutic methods of the current era experiment with ways specific to each art, to achieve interdisciplinary exchanges. They connect to disciplines such as psychology or psychiatry, anthropology, history, religion, to experience the primary therapeutic values of contemporary art.
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Bayiyana, Alice, Samuel Okurut, Rose Nabatanzi, Godfrey Zziwa, David R. Boulware, Fredrick Lutwama y David Meya. "Longitudinal Changes in Cd4+, Cd8+ T Cell Phenotype and Activation Marker Expression Following Antiretroviral Therapy Initiation among Patients with Cryptococcal Meningitis". Journal of Fungi 5, n.º 3 (17 de julio de 2019): 63. http://dx.doi.org/10.3390/jof5030063.

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Despite improvement in the prognosis of HIV/AIDS (human immunodeficiency virus/acquired immune deficiency syndrome) patients on antiretroviral therapy (ART), cryptococcal meningitis (CM) still causes 10–15% mortality among HIV-infected patients. The immunological impact of ART on the CD4+ and CD8+ T cell repertoire during cryptococcal co-infection is unclear. We determined longitudinal phenotypic changes in T cell subsets among patients with CM after they initiated ART. We hypothesized that ART alters the clonotypic phenotype and structural composition of CD4+ and CD8+ T cells during CM co-infection. For this substudy, peripheral blood mononuclear cells (PBMC) were isolated at four time points from CM patients following ART initiation during the parent study (ClinicalTrials.gov number, NCT01075152). Phenotypic characterization of CD4+ and CD8+ T cells was done using T cell surface marker monoclonal antibodies by flow cytometry. There was variation in the expression of immunophenotypic markers defining central memory (CD27+CD45R0+), effector memory (CD45R0+CD27–), immune activation (CD38+ and Human Leucocyte Antigen DR (HLA-DR+), and exhaustion (Programmed cell death protein one (PD-1) in the CD4+ T cell subset. In comparison to the CD4+ T cell population, the CD8+ central memory subset declined gradually with minimal increase in the effector memory subset. Both CD4+ and CD8+ T cell immune exhaustion and activation markers remained elevated over 12 weeks. The relative surge and decline in the expression of T cell surface markers outlines a variation in the differentiation of CD4+ T cells during ART treatment during CM co-infection.
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Roviello, Giandomenico, Martina Catalano, Raffaella Santi, Valeria Emma Palmieri, Gianmarco Vannini, Ilaria Camilla Galli, Eleonora Buttitta, Donata Villari, Virginia Rossi y Gabriella Nesi. "Immune Checkpoint Inhibitors in Urothelial Bladder Cancer: State of the Art and Future Perspectives". Cancers 13, n.º 17 (31 de agosto de 2021): 4411. http://dx.doi.org/10.3390/cancers13174411.

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Bladder cancer (BC) is the most common malignancy of the genitourinary tract, with high morbidity and mortality rates. Until recently, the treatment of locally advanced or metastatic urothelial BC was based on the use of chemotherapy alone. Since 2016, five immune checkpoint inhibitors (ICIs) have been approved by the Food and Drug Administration (FDA) in different settings, i.e., first-line, maintenance and second-line treatment, while several trials are still ongoing in the perioperative context. Lately, pembrolizumab, a programmed death-1 (PD-1) inhibitor, has been approved for Bacillus Calmette–Guérin (BCG)-unresponsive high-risk non-muscle invasive bladder cancer (NMIBC), using immunotherapy at an early stage of the disease. This review investigates the current state and future perspectives of immunotherapy in BC, focusing on the rationale and results of combining immunotherapy with other therapeutic strategies.
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Ivanov, Nedelcho, Boris Krastev, Dimitrina Georgieva Miteva, Hristiana Batselova, Radostina Alexandrova y Tsvetelina Velikova. "Effectiveness and safety of COVID-19 vaccines in patients with oncological diseases: State-of-the-art". World Journal of Clinical Oncology 14, n.º 9 (24 de septiembre de 2023): 343–56. http://dx.doi.org/10.5306/wjco.v14.i9.343.

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Developing novel cancer therapies that exploit programmed cell death pathways holds promise for advancing cancer treatment. According to a recently published study in Science, copper death (cuproptosis) occurs when intracellular copper is overloaded, triggering aggregation of lipidated mitochondrial proteins and Fe–S cluster proteins. This intriguing phenomenon is triggered by the instability of copper ions. Understanding the molecular mechanisms behind cuproptosis and its associated genes, as identified by Tsvetkov, including ferredoxin 1, lipoic acid synthase, lipoyltransferase 1, dihydrolipid amide dehydrogenase, dihydrolipoamide transacetylase, pyruvate dehydrogenase α1, pyruvate dehydrogenase β, metallothionein, glutaminase, and cyclin-dependent kinase inhibitor 2A, may open new avenues for cancer therapy. Here, we provide a new understanding of the role of copper death and related genes in cancer.
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Bolognini, Maurizio. "The SMSMS Project: Collective Intelligence Machines in the Digital City". Leonardo 37, n.º 2 (abril de 2004): 147–49. http://dx.doi.org/10.1162/0024094041139247.

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The SMSMS project is a computer-based interactive installation that derives from the author's previous work, Computer sigillati, in which 200 machines have been programmed to produce an endless flow of random images and left to work indefinitely without being connected to a monitor. In SMSMS, one of the Computer sigillati programs is employed to create images that are visible and can be modified by the public using cell phones. SMSMS could be considered as either an exercise in collective intelligence or, in contrast, as a disturbance to the unpredictable working of the machine. Some implications concerning art and new technologies are discussed.
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40

Hollingshaus, Wade. "A Literary (Techno)science". Nordic Theatre Studies 31, n.º 1 (14 de marzo de 2019): 58–72. http://dx.doi.org/10.7146/nts.v31i1.113001.

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Beginning in the late 1970s, Finland’s Erkki Kurenniemi (1941-2017) actively labored to archive every possible aspect of his life. He took photos, made videos, and collected his tram tickets, receipts, body hairs, etc. Kurenniemi believed that within the next forty years, computer technoscience will have advanced sufficiently that it could be programmed to interpret the data of his archive and—on his 107th birthday, 10 July 2018—resurrect his consciousness. For Kurenniemi, this project was an experiment in the realms of neuroscience and artificial intelligence. However, it can also be seen as an experiment in aesthetics, or in what Jacques Rancière calls the “aesthetic regime” of art—an aesthetic-political historical framework imbued with the dynamics of democracy, where “everything speaks.” This article reframes Kurenniemi’s work within the aesthetic regime of art to draw attention to the “silent speech” and “aestheticunconscious” (Rancière) of the work and what is the literary nature of Kurenniemi’s experiments with (techno)science.
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41

Chiesa-Estomba, Carlos M., Miguel Mayo-Yanez, Orlando Guntinas-Lichius, Vincent Vander-Poorten, Robert P. Takes, Remco de Bree, Gyorgy B. Halmos, Nabil F. Saba, Sandra Nuyts y Alfio Ferlito. "Radiomics in Hypopharyngeal Cancer Management: A State-of-the-Art Review". Biomedicines 11, n.º 3 (6 de marzo de 2023): 805. http://dx.doi.org/10.3390/biomedicines11030805.

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(1) Background: Hypopharyngeal squamous cell carcinomas usually present with locally advanced disease and a correspondingly poor prognosis. Currently, efforts are being made to improve tumor characterization and provide insightful information for outcome prediction. Radiomics is an emerging area of study that involves the conversion of medical images into mineable data; these data are then used to extract quantitative features based on shape, intensity, texture, and other parameters; (2) Methods: A systematic review of the peer-reviewed literature was conducted; (3) Results: A total of 437 manuscripts were identified. Fifteen manuscripts met the inclusion criteria. The main targets described were the evaluation of textural features to determine tumor-programmed death-ligand 1 expression; a surrogate for microvessel density and heterogeneity of perfusion; patient stratification into groups at high and low risk of progression; prediction of early recurrence, 1-year locoregional failure and survival outcome, including progression-free survival and overall survival, in patients with locally advanced HPSCC; thyroid cartilage invasion, early disease progression, recurrence, induction chemotherapy response, treatment response, and prognosis; and (4) Conclusions: our findings suggest that radiomics represents a potentially useful tool in the diagnostic workup as well as during the treatment and follow-up of patients with HPSCC. Large prospective studies are essential to validate this technology in these patients.
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42

Kogler, Susanne. "Art as a Critique of Language: On the Continuity of the Tradition of the Avant-Garde Aesthetic in the Modern and the Postmodern". Musicological Annual 43, n.º 2 (1 de diciembre de 2007): 287–303. http://dx.doi.org/10.4312/mz.43.2.287-303.

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That art functions as a corrective to rational-scientific insights is one of the formative thoughts of art philosophy. The fact that artistic expression represents a corrective to linguistically-rationally affected insight also ranks among the constants of art philosophy in the 20th century. “Expression is the opponent of articulating something” can be read, for instance, in Adorno’s Aesthetic Theory with regards to the character of language in art and Jean François Lyotard wrote on aesthetic experience: “What happens to us is by no means something which we would have controlled, programmed or conceptually apprehended beforehand”. The uneducible, conceptually unattainable is also at the centre of current art production of the 21st century. On the basis of Lyotard’s and Adorno’s positions, the article shows that one should acknowledge a constancy of the topos of art as non-conceptual knowledge on the one hand as the continuing function of a tradition defined from the philosophical aesthetics of modernity to post-modernity and orientated on the artistic avant-garde. On the other hand and beyond this a continuous line of tradition of New Music becomes clear, leading to the expressionistic avant-garde of the 20th century which represented the starting point for Adorno’s music philosophy, through Lyotard’s focus on John Cage, up to the avant-garde of New Music in the era of post modernity. Specific features of contemporary art, such as rebellion against linguistic standards, an understanding of expressivity that opposes the traditional language of music and operates on the verge of silence, as well as the utopian vision of a modified reality which aims at transcendency enable a conception of art as non-conceptual knowledge, corresponding with the positions of art philosophy in modernity and post-modernity in important points. The relevance of focusing on this line of tradition for musicology lies in the fact that it sheds new light on the musical avant-garde and its further function and, last but not least, that it opens new perspectives in understanding contemporary artistic productions.
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Fiorentino, Vincenzo, Cristina Pizzimenti, Mariausilia Franchina, Ludovica Pepe, Fernanda Russotto, Pietro Tralongo, Marina Gloria Micali, Gaetano Basilio Militi y Maria Lentini. "Programmed Cell Death Ligand 1 Immunohistochemical Expression and Cutaneous Melanoma: A Controversial Relationship". International Journal of Molecular Sciences 25, n.º 1 (4 de enero de 2024): 676. http://dx.doi.org/10.3390/ijms25010676.

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Cutaneous melanoma (CM) is traditionally considered one of the most “immunogenic” tumors, eliciting a high immune response. However, despite the presence of tumor-infiltrating lymphocytes (TILs), melanoma cells use strategies to suppress antitumor immunity and avoid being eliminated by immune surveillance. The PD-1 (programmed death-1)/PD-L1 (programmed death-ligand 1) axis is a well-known immune escape system adopted by neoplastic cells. Therefore, immunotherapy with PD-1 and PD-L1 inhibitors is quickly becoming the main treatment approach for metastatic melanoma patients. However, the clinical utility of PD-L1 expression assessment in CM is controversial, and the interpretation of PD-L1 scores in clinical practice is still a matter of debate. Nonetheless, the recent literature data show that by adopting specific PD-L1 assessment methods in melanoma samples, a correlation between the expression of such a biomarker and a positive response to PD-1-based immunotherapy can be seen. Our review aims to describe the state-of-the-art knowledge regarding the prognostic and predictive role of PD-L1 expression in CM while also referring to possible biological explanations for the variability in its expressions and related treatment responses.
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Stefańska, Katarzyna, Małgorzata Józkowiak, Paweł Antosik, Dorota Bukowska, Piotr Celichowski, Małgorzata Bruska, Michał Nowicki et al. "Genes regulating programmed cell death are significantly upregulated in porcine immature oocytes". Medical Journal of Cell Biology 7, n.º 1 (1 de julio de 2019): 1–10. http://dx.doi.org/10.2478/acb-2019-0001.

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AbstractCorrect maturation of the oocyte is crucial for further fertilization and embryogenesis. It comprises of both nuclear and cytoplasmic maturation, during which the proteins, nutrients and mRNAs are assembled. Cumulus cells are connected with the oocyte via gap-junctions, which enable bi-directional transfer of molecules, forming cumulus-oocyte complex (COC). The expression pattern in CCs is thought to resemble the genes expressed in the oocyte. The CCs surrounding the gamete of high developmental competence have an increased expression of apoptotic markers. Therefore, our aim in this study was to determine whether any apoptosis-related genes are upregulated in porcine oocytes before or after IVM. We isolated COCs from 45 pubertal crossbred gilts, performed brilliant cresyl blue (BCB) staining and analyzed the gene expression pattern in oocytes before and after IVM with the use of microarray analysis. The results include 419 differentially expressed transcripts, 25 of which belong to „regulation of apoptosis” and „regulation of cell death” GO BP terms. This set of genes includes BCLAF1, EIF2AK3, KLF10, MIF, MAP3K1, NOTCH2, TXNIP and APP, all of which have been upregulated in immature porcine oocytes. Our results suggest that they play part in porcine oocyte maturation and could be used as potential markers of female gamete’s developmental competence. This knowledge could serve as a basis to improve ART in pigs.
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Zhang, Lin, Weihao Lin, Zhenlin Yang, Renda Li, Yibo Gao y Jie He. "Multimodality Treatment of Pulmonary Sarcomatoid Carcinoma: A Review of Current State of Art". Journal of Oncology 2022 (25 de marzo de 2022): 1–11. http://dx.doi.org/10.1155/2022/8541157.

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Pulmonary sarcomatoid carcinoma (PSC) is an unconventional non-small-cell lung cancer (NSCLC) that is currently managed under guidelines used for conventional NSCLC and has poor survival. Surgery is the optimal choice for resectable PSC, and the prevalence of mutations in this type of tumor laid the foundation for novel systemic therapies such as targeted therapy and immunotherapy. PSC is resistant to chemotherapy and radiotherapy, and the effects of the 2 therapies are controversial. Targeted therapies have been reported to confer survival benefits, and savolitinib, an oral selective MET tyrosine-kinase inhibitor, has been approved in metastatic patients with MET exon 14 skipping mutations. Expression and positive rate of programmed death ligand 1 in PSC are high; our previous research has also revealed a high mutational burden and a T-cell-inflamed microenvironment of PSC. Correspondingly, immune checkpoint inhibitors have shown preliminary antitumor effects (overall response rates of 40.5% (15/37) and 31.6% (6/19) in two retrospective studies, respectively) in PSC patients. In summary, patients should receive operations at an early stage and multimodality treatments are needed to maximize the benefits of patients with advanced disease.
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46

Rust, Blake J., Leslie S. Kean, Lucrezia Colonna, Katherine E. Brandenstein, Nikhita H. Poole, Willimark Obenza, Mark R. Enstrom et al. "Robust expansion of HIV CAR T cells following antigen boosting in ART-suppressed nonhuman primates". Blood 136, n.º 15 (8 de octubre de 2020): 1722–34. http://dx.doi.org/10.1182/blood.2020006372.

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Abstract Chimeric antigen receptor (CAR) T cells targeting CD19+ hematologic malignancies have rapidly emerged as a promising, novel therapy. In contrast, results from the few CAR T-cell studies for infectious diseases such as HIV-1 have been less convincing. These challenges are likely due to the low level of antigen present in antiretroviral therapy (ART)-suppressed patients in contrast to those with hematologic malignancies. Using our well-established nonhuman primate model of ART-suppressed HIV-1 infection, we tested strategies to overcome these limitations and challenges. We first optimized CAR T-cell production to maintain central memory subsets, consistent with current clinical paradigms. We hypothesized that additional exogenous antigen might be required in an ART-suppressed setting to aid expansion and persistence of CAR T cells. Thus, we studied 4 simian/HIV-infected, ART-suppressed rhesus macaques infused with virus-specific CD4CAR T cells, followed by supplemental infusion of cell-associated HIV-1 envelope (Env). Env boosting led to significant and unprecedented expansion of virus-specific CAR+ T cells in vivo; after ART treatment interruption, viral rebound was significantly delayed compared with controls (P = .014). In 2 animals with declining CAR T cells, rhesusized anti–programmed cell death protein 1 (PD-1) antibody was administered to reverse PD-1–dependent immune exhaustion. Immune checkpoint blockade triggered expansion of exhausted CAR T cells and concordantly lowered viral loads to undetectable levels. These results show that supplemental cell-associated antigen enables robust expansion of CAR T cells in an antigen-sparse environment. To our knowledge, this is the first study to show expansion of virus-specific CAR T cells in infected, suppressed hosts, and delay/control of viral recrudescence.
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Sayidiman, Sayidiman, Hikmawati Usman y Nasaruddin Nasaruddin. "E-Learning Module Music In PGSD FIP UNM". Publikasi Pendidikan 10, n.º 3 (19 de noviembre de 2020): 240. http://dx.doi.org/10.26858/publikan.v10i3.16105.

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This research was conducted to design and test on a small scale the results of the design of the art learning module Music at the PGSD FIP UNM. In particular, this study aims to describe the description of the design of music e-learning modules in the UNM FIP PGSD Study Program. The research method used research development (R & D), the test subjects were the PGSD FIP UNM students who had programmed the Music Arts course. Sampling is done by using a simple random sampling technique with a number of sample members of 30 people, the data collection techniques using a closed questionnaire, analysis of data using the data analysis descriptive and inferential statistics. The results Showed that there was an Increase in participation and student learning outcomes classically after learning to use e modules, the weakness of e modules was that they were not Able to encourage students who had the ability more towards Reviews their maximum potential in terms of learning the art of music.
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48

Nechytalyuk, Iryna. "Тілесність у проекті Олександра Довженка «Земля»: аспекти перформативності". Bibliotekarz Podlaski Ogólnopolskie Naukowe Pismo Bibliotekoznawcze i Bibliologiczne 51, n.º 2 (16 de agosto de 2021): 123–36. http://dx.doi.org/10.36770/bp.603.

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With the emergence and development of the cinema as art, a definition of corporeality was attributed with a new sense. Cinema as an art type is programmed towards interactions with corporeality. Performance researchers, Fisher-Liсhte in particular, consider it significant to implement something or transform something towards a corporal practice. Such an example may be exchange of energy during a theatrical performance, in the course of an active interaction between actors. In the paper the performative aspects of corporeality are studied in details, Ivan’s Death and Natalka’s Wailing episodes in particular. It is concluded that in Dovzhenko’s view, the body is beautiful despite age (a close-up of the old man whose face is shining like the face of a saint), sex or a social role. Oleksandr Dovzhenko’s findings as the director and Danylo Demuztsky’s work as the photography director reflect the performative features of corporeality and influence its understanding by the public. In La Terra, common things get sacral meaning, spirituality is perceived through the body aspect.
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Pial, Mohammad Mohtasim Hamid, Asahi Tomitaka, Nezih Pala y Upal Roy. "Implantable Devices for the Treatment of Breast Cancer". Journal of Nanotheranostics 3, n.º 1 (9 de febrero de 2022): 19–38. http://dx.doi.org/10.3390/jnt3010003.

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Breast cancer is one of the leading causes of death in the female population worldwide. Standard treatments such as chemotherapy show noticeable results. However, along with killing cancer cells, it causes systemic toxicity and apoptosis of the nearby healthy cells, therefore patients must endure side effects during the treatment process. Implantable drug delivery devices that enhance therapeutic efficacy by allowing localized therapy with programmed or controlled drug release can overcome the shortcomings of conventional treatments. An implantable device can be composed of biopolymer materials, nanocomposite materials, or a combination of both. This review summarizes the recent research and current state-of-the art in these types of implantable devices and gives perspective for future directions.
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Münzmay, Andreas y Christine Siegert. "Phonographischer Text, Interpretation und Aufführungsmaterial als kritisch edierbarer Sachzusammenhang". Editio 33, n.º 1 (1 de noviembre de 2019): 10–30. http://dx.doi.org/10.1515/editio-2019-0002.

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Abstract The article discusses possibilities and specific problems of including audio material in the realm of scholarly music editions. From this perspective, the authors propose to include the sounding manifestation of music both into the notion of the musical ‚work‘ and of the musical ‚text‘. The outcome of this thought experiment which considers music as performative art, Beethoven’s and other classical composers’ own wider notions of musical works as musical practice, phonographic recordings as text, different types of music as different types of data, programmed concordances as specific feature of digital editions, and musical interpreters as authors of musical interpretations is a theoretical model that for the first time makes record productions the object of scholarly critical edition.
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