Tesis sobre el tema "Produits chimiques du caoutchouc"
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Haicour, Philippe. "La brevetabilité des produits chimiques". Paris 2, 1992. http://www.theses.fr/1992PA020103.
Texto completoA french patent directly protects chemicals as products and indirectly as results of manufacture processes or as applications means. That is ordinary and straight follows from the law of 1944. Since, chemistry highly advanced and mainly in the scope of molecular structures which were ignored by former science, technics and of course, industrial property rights. As former law, new ones such as this of 1968 and the epc are well fifted to the protection of material objets physically at human scale. Their provisions no more harmonize with protection of infinitesimal molecules than they do with new objets the industry uses today, such as new plant varieties, computer programs or integrated circuits. Moreover, the material tools, the law protects as inventions, are intented to definite uses apparent through their forms. In return, the same molecule may be used in various applications without any physical alteration in its presentatio. Regulations have yet taken in account such features. The patent law often interferes with it and will no longer be mended with dissimilar provisions as those relating to medecines, or the second therapeutical or non therapeutical applications or, may be soon, to biochemically modified plants and animals
Brass, Olivier. "Interactions physico-chimiques des produits de. ." Lyon 1, 1992. http://www.theses.fr/1992LYO1T257.
Texto completoAvrillon, Yvan. "Traitements chimiques de l'hyperesthésie dentinaire". Nantes, 1999. http://www.theses.fr/1999NANT008D.
Texto completoPhetphaisit, Chor Wayakron. "A study of preparation of light colored photosensitive liquid natural rubber". Le Mans, 2003. http://cyberdoc.univ-lemans.fr/theses/2003/2003LEMA1019.pdf.
Texto completoBois, Frédéric. "Modélisation mathématique de la cancérogenèse par des produits chimiques". Metz, 1988. http://docnum.univ-lorraine.fr/public/UPV-M/Theses/1988/Bois.Frederic.SMZ889.pdf.
Texto completoA mathematical model of carcinogenesis is described for the case of vinyl chloride. The model includes a description of toxicokinetics, metabolism, cellular action of the compound. An assessment of the risk of cancer from drinking water contaminants is presented. For the risk estimates, confidence intervals have been obtained by Monte-Carlo simulations
Bois, Frédéric. "Modélisation mathématique de la cancérogenèse par des produits chimiques". Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb37612025d.
Texto completoBois, Frédéric Vasseur Paule. "MODELISATION MATHEMATIQUE DE LA CANCEROGENESE PAR DES PRODUITS CHIMIQUES /". [S.l.] : [s.n.], 1988. ftp://ftp.scd.univ-metz.fr/pub/Theses/1988/Bois.Frederic.SMZ889.pdf.
Texto completoBenaissa, Wassila Gabas Nadine Cabassud Michel. "Développement d'une méthodologie pour la conduite en sécurité d'un réacteur continu intensifié". Toulouse : INP Toulouse, 2008. http://ethesis.inp-toulouse.fr/archive/00000356.
Texto completoGarnier, Bertrand. "Etude du couplage entre transferts thermiques et reactions chimiques. Application a la vulcanisation du caoutchouc". Nantes, 1990. http://www.theses.fr/1990NANT2073.
Texto completoVERDOUCQ, ACHTE ISABELLE. "Etude epidemiologique de mortalite dans une usine de produits chimiques". Lille 2, 1994. http://www.theses.fr/1994LIL2M167.
Texto completoAlain, Eléonore. "Optimisation des paramètres chimiques du circuit primaire des centrales électronucléaires". Paris 6, 1997. http://www.theses.fr/1997PA066772.
Texto completoTitah-Benbouzid, Hosna. "Comportement physico-chimique des produits chimiques déversés accidentellement en milieu marin". Phd thesis, Université de Bretagne occidentale - Brest, 2010. http://tel.archives-ouvertes.fr/tel-00744690.
Texto completoJoussein, Emmanuel. "L'halloysite : origine de la variabilité des propriétés physico-chimiques". Poitiers, 2004. http://www.theses.fr/2004POIT2343.
Texto completoHalloysite clay minerals occur widely around the world, and are a major component of Andisols and soils derived from volcanic materials in wet tropical and subtropical regions. The structure and chemical composition of halloysite are similar to those of kaolinite but the unit layers in halloysite are separated by a monolayer of water molecules. However, halloysites present various characteristics toward their cation exchange capacity, potassium selectivity, hydration state, and intercalation properties. To better understand their physical chemical properties, reference and soil halloysites were used. The hydration state and the presence of charges are the key factor controlling the specific properties of halloysite. For the same sample, the intercalation of organic molecules or salts is favoured when the halloysite is hydrated. Their charge properties and K selectivity are influenced by the hydratation state. Many charged sites becomes innaccessible after dehydration. The presence of permanent charge due to heterovalent substitutions or to impurities was not evidenced in the studied samples. These permanent charges could be induce by structural defects due to defects in the distribution of protons
Hermelin, Damien. "Modélisation de dispositifs à ondes élastiques de surface en milieu contraint mécaniquement et applications". Besançon, 2010. http://www.theses.fr/2010BESA2037.
Texto completoThe manuscrit concerns the development of surface acoustic waves sensors for wireless monitoring of physical parameters dedicated to biomedical applications, and more specially for blood pressure monitoring. The work consists first in the development of a new physical modeling for surfac acoustic wave device submitted to inhomogeneous stress distribution. The model is detailed and used to optimise geometric size of a membrane-based pressure sensor. The study focuses on quartz based solution but can be applied to any piezoelectric material. This manuscript also presents the sensor construction. The application as sensor has been validated and compared with results obtained with the above evolve model. Comparisons between experimental and theoretical reveals a quite good agreement and allows to validate the model reliability and the efficiency of the proposed optimization, and the model had no equivalent until now. The developped model yields new computation tools which allows acurate and fast design acoustic wave devices sensors for measuring mechanical parameters as illustrated throughout the manuscript. The final application concerns blood pressure monitoring using an external use of the sensor
Romestant, Damien. "Le commerce international des matériels et produits sensibles". Montpellier 1, 2002. http://www.theses.fr/2002MON10070.
Texto completoGoulet, Lise 1953. "Association entre la mortinatalite et lexposition aux produits chimiques pendant la grossesse". Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=75883.
Texto completoA case control study was conducted among women working in three sectors: Health, Personal services and Agriculture, and Manufacturing industries. Two hundred and twenty-seven (227) stillbirths aged 20 weeks of gestation or more, were matched to two hundred and twenty-seven (227) livebirths, for mother's age, gravidity and socio-economic status. Chemicals were divided into ten (10) groups. Exposure was assessed by visits to the workplaces, telephone calls or extrapolations. Conditional logistic regression analyses were done.
Women working as hairdressers-beauticians$ sp+$ (O.R. 0,01 (0,00-0,34)) and those working in the garment industry* (O.R. 0,24 (0,08-0,77)) had significantly less stillbirths while women working in metal-electrical-chemical industries* (O.R. 5,11 (0,99-26,37)) had a significant excess of stillbirth. Exposure to pesticides/germicides, irrespective of the level or frequency$ sp+$ (O.R. 2,06 (1,15-3,68)), and occasional exposure to "miscellaneous" chemicals (other chemicals potentially fetotoxic)* (O.R. 12,07 (1,22-119,9)) showed a significant increased risk of stillbirth while exposure to a low level of metals$ sp+$ (O.R. 0,28(0,10-0,83)) showed a significantly lower risk of stillbirth.
Leatherworkers* (O.R. 2,59 (0,47-14,33)), women working in the textile industry$ sp+$ (O.R. 2,55 (0,42-15,41)), agricultural workers* (O.R. 3,88 (0,47-31,88)), women exposed to a moderate (2) level of metals$ sp+$ (O.R. 2,32 (0,59-9,10)) and those exposed to a high (3) level of solvents$ sp+$ (O.R. 2,49 (0,47-13,30)) had a non significant (P $>$ 0,05) increased risk of stillbirth.
The author proposes that ergonomic factors could be a confounder of the association between stillbirth and exposure to pesticides/germicides or metals. A study looking more closely at the association between stillbirth and ergonomic factors is therefore suggested. Because exposure of pregnant workers to elevated levels of chemicals is quite rare, further epidemiological studies should include more subjects. ftn$ sp+$: stillbirths aged 20 weeks of gestation or more. ftn*: stillbirths aged 28 weeks of gestation or more.
Diyani, Samira. "Elaboration d'un sel industriel : Le chlorure de potassium conception et mise au point d'un nouveau procédé de purification". Mulhouse, 1997. http://www.theses.fr/1997MULH0480.
Texto completoBenaissa, Wassila. "Développement d'une méthodologie pour la conduite en sécurité d'un réacteur continu intensifié". Phd thesis, Toulouse, INPT, 2006. http://oatao.univ-toulouse.fr/7500/1/benaissa.pdf.
Texto completoBenaissa, Wassila. "Développement d'une méthodologie pour la conduite en sécurité d'un réacteur continu intensifié". Phd thesis, Toulouse, INPT, 2006. https://hal.science/tel-04576129.
Texto completoThe aim of this study is to develop a methodology in order to carry out safely an exothermic reaction in an intensified continuous reactor. It is established on a case study: the transposition of the esterification between propionic anhydride and 2-butanol in a new prototype of heatexchanger/reactor. The approach is divided in three steps. In a first part, experimental data obtained by calorimetry allow to determine the potential hazard of the compounds as well as the reaction and a kinetic model is validated. In a second stage a dedicated software model is used to calculate optimal operating conditions for safe control. Experiments are then achieved to test these conditions. In the last step, the inherently safer behaviour of the reactor is evaluated in the case of probable malfunctions (fluids shutdown) due to the thermal inertia of the apparatus. Finally, the evolution of the temperature profiles is obtained by dynamic simulation
Hayat, Aktar. "Biocapteurs pour la détection de deux biotoxines : l'acide okadaique et l'ochratoxine A". Perpignan, 2012. http://www.theses.fr/2012PERP1110.
Texto completoThis work was focused on the development of new bioanalytical methods, exploring different bioreceptors, immobilization techniques and transduction methods, for the detection of okadaic acid (OA) and ochratoxin A (OTA) in food samples. The first part was based on the development of colorimetric assays by exploiting the inhibitory effect of the OA on protein phosphatase 2A (PP2A). PP2A purchased from GTP Technology, ZEU Immunotec and Millipore was entrapped within several membranes: photopolymers, sol-gel and agarose gels. These different immobilization techniques were tested, optimized and compared to detect OA. The second part was focused on the development of colorimetric and electrochemical immunoassays for OA detection. Enzyme-linked indirect competitive immunoassays based on OA immobilization via MBs and diazonium chemistry were developed both in batch and automated flow mode. To avoid the complexity involved in labeling of biomolecules, label-free detection techniques based on antibody immobilization via physical adsorption, protein-G-Mbs and covalent attachment were also investigated to detect OA. In the third part, the development of aptasensors for the detection of OTA was carried out. The aptasensor were based on MBs and click chemistry to perform the labeled and non-labeled electrochemical detection
Blondin, Catherine. "Polysaccharides sulfatés extraits d'algues brunes : activité anticomplémentaire des fucanes". Paris 13, 1992. http://www.theses.fr/1992PA132041.
Texto completoDrevelle, Christophe Delobel René Duquesne Sophie Le Bras Michel. "Étude de la dégradation de films à base de résine acrylique utilisée dans l'industrie textile". [S.l.] : [s.n.], 2002. http://www.univ-lille1.fr/bustl-grisemine/pdf/memoires/F2002-153.pdf.
Texto completoSur la p. de titre : DEA-Structure et dynamique des systèmes réactifs, PERF-Procédés d'élaboration de revêtements fonctionnels. Bibliogr. f. : 21-22. Annexes.
Lefaux, Sandra Tremblin Gérard. "Biodégradation de films polymères à usage agricole caractérisation physico-chimique des résidus et identification biomoléculaire des bactéries actives /". [S.l.] : [s.n.], 2005. http://cyberdoc.univ-lemans.fr/theses/2005/2005LEMA1011.pdf.
Texto completoSavary, Saôde. "État de la gestion environnementale dans les PME de produits chimiques au Québec". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0016/MQ56968.pdf.
Texto completoGuldemann, Joan. "Evaluation du potentiel de sensibilisation de produits chimiques en fonction de leur réactivité". Thesis, Strasbourg, 2013. http://www.theses.fr/2013STRAF052.
Texto completoContact dermatitis is one of the most common health problems and is highly prevalent in industrialized countries. Currently, only the total eviction of the allergen can prevent further allergic reactions. Since several years, different tests have been developed to determine the sensitization potential of a large number of compounds. Some of them are based on animal models. However, the cosmetic legislation now bans this kind of tests. In this context, the development of integrated strategies based on in silico, in chemico and on in vitro assays seems to be necessary. The aim of this PhD work is to compare reactivity data from in chemico tests realized at the laboratory, with biological data obtained from in vitro tests concerning the activation of the Keap1/Nrf2/ARE pathway in THP-1 and MoDCs dendritic cells (INSERM UMR-996). The reactivity of 10 compounds known for their implication in allergic contact dermatitis has been studied to show if a correlation exists between the potential of sensitization of allergens and the oxidative stress inducing dendritic cells maturation
Millet, Mélanie. "Composition et mécanismes de formation des troubles physico-chimiques dans les produits cidricoles". Thesis, Rennes, Agrocampus Ouest, 2018. http://www.theses.fr/2018NSARB311/document.
Texto completoPhysico-chemical haze appearance during storage of clarified apple-based beverages is a concern for producers. These hazes are caused by interactions between several constituents of the beverage that lead to the formation of visible aggregates. This work had two main goals: analyze the composition of hazes in order to determine which families of compounds are responsible for their formation, and understand which mechanisms are involved. First, the composition of the haze gathered from three apple-based beverages (cider, apple juice and pommeau) was analyzed. The results revealed the implication of phenolic compounds and led to the hypothesis that their oxidation was probably one of the main factors responsible for haze formation. Proteins were found in quite large quantities in some apple juice hazes, which suggests their involvement in haze formation in this beverage.These two hypotheses have been verified using two model approaches: in a model pommeau and in a model apple juice. This work evidenced that different kinds of hazes exist in apple-based beverages. On the one hand, haze in pommeaux and ciders is mainly explained by procyanidin oligomers self-aggregation induced by their oxidation, with possible interactions with other beverage constituents. On the other hand, haze in some apple juices, which probably contain low polyphenol and high protein levels, is triggered by “Pathogenesis-Related Proteins” denaturation that lead to their self-aggregation, in interaction with oligomeric procyanidins
Ahmadi, Mitra. "Nouveaux radiotraceurs peptidiques pour l'imagerie nucléaire : radiomarquage, évaluations physico-chimiques et pharmacologiques". Grenoble 1, 2008. http://www.theses.fr/2008GRE10010.
Texto completoDuring the past decade, radiolabeled peptides have emerged as an important class of radiopharmaceuticals for diagnosis and therapy in nuclear medicine. The concept of using radiolabeled peptides in vivo stimulates a large body of research for new peptidic vectors but also for radiochemical and radiopharmaceutical evaluations of these peptides after labeling. We studied and optimized the 99m-technetium, 125-iodine and 111-indium radiolabeling of a serie of peptides in order to allow the in vivo use of these tracers for imaging studies of three pathologies: tumoral angiogenesis, atherosclerosis and systemic lupus erythematosus. The radiolabeling with technetium was carried out using a tricarbonyle agent (lsoLink) and Indium was linked by DOTA macromolecule. Radioiodination was realized by electrophilic substitution. The reaction parameters were defined so that the labeling reaction presents a high radiochemical purity (>95%) and a high specifie activity. The reactions were fast and reproducible. Various physicochemical and pharmacokinetic properties (Iipophily, stability of labeling in vitro and in vivo, non-specifie fixation, metabolization and organ biodistribution of peptides) were studied. These results permitted to select the best peptide for in vivo imaging
Ciceron, Philippe. "Etude du (tétraméthyl-1,1,3,3)butyl-4 phénol, et de ses dérivés hydroxyméthyles et de ses produits de condensation avec le formaldéhyde pour la vulcanisation du caoutchouc butyle". Lyon 1, 1988. http://www.theses.fr/1988LYO10055.
Texto completoLe, Thi Xuan Phuong. "Allergies respiratoires aux substances chimiques et médicamenteuses". Paris 5, 1997. http://www.theses.fr/1997PA05P181.
Texto completoJarry, Joëlle. "Etude de la toxicité des produits de degradation thermique de composes agro-pharmaceutiques". Rouen, 1992. http://www.theses.fr/1992ROUEO3TP.
Texto completoGrenet, Ingrid. "De l’utilisation des données publiques pour la prédiction de la toxicité des produits chimiques". Thesis, Université Côte d'Azur (ComUE), 2019. http://www.theses.fr/2019AZUR4050.
Texto completoCurrently, chemical safety assessment mostly relies on results obtained in in vivo studies performed in laboratory animals. However, these studies are costly in term of time, money and animals used and therefore not adapted for the evaluation of thousands of compounds. In order to rapidly screen compounds for their potential toxicity and prioritize them for further testing, alternative solutions are envisioned such as in vitro assays and computational predictive models. The objective of this thesis is to evaluate how the public data from ToxCast and ToxRefDB can allow the construction of this type of models in order to predict in vivo effects induced by compounds, only based on their chemical structure. To do so, after data pre-processing, we first focus on the prediction of in vitro bioactivity from chemical structure and then on the prediction of in vivo effects from in vitro bioactivity data. For the in vitro bioactivity prediction, we build and test various models based on compounds’ chemical structure descriptors. Since learning data are highly imbalanced in favor of non-toxic compounds, we test a data augmentation technique and show that it improves models’ performances. We also perform a largescale study to predict hundreds of in vitro assays from ToxCast and show that the stacked generalization ensemble method leads to reliable models when used on their applicability domain. For the in vivo effects prediction, we evaluate the link between results from in vitro assays targeting pathways known to induce endocrine effects and in vivo effects observed in endocrine organs during longterm studies. We highlight that, unexpectedly, these assays are not predictive of the in vivo effects, which raises the crucial question of the relevance of in vitro assays. We thus hypothesize that the selection of assays able to predict in vivo effects should be based on complementary information such as, in particular, mechanistic data
GOY, CHRISTEL. "Odeur à l'épandage de lisier : produits chimiques de désodorisation : stratégie de validation de formulations". Rennes 1, 1995. http://www.theses.fr/1995REN10161.
Texto completoDien, Jean-Michel. "Contribution à l'étude de la sécurité des procédés chimiques conduisant à des décompositions autocatalysées". Mulhouse, 1995. http://www.theses.fr/1995MULH0407.
Texto completoSimonetti, Estelle. "Synthèses et études physico-chimiques de composés amphiphiles dérivés du Tham". Avignon, 2005. http://www.theses.fr/2005AVIG0222.
Texto completoDayyani-Najafabadi, Abdol Rasoul. "La responsabilité du fait de défaut de sécurité des produits". Université Robert Schuman (Strasbourg) (1971-2008), 1996. http://www.theses.fr/1996STR30020.
Texto completoThis study involes a preliminary part about doctrinal debates concerning the new regime of product liability as well as an analysis about its different material sources. The most important one is the council directive of 25th. July 1985, which study helps to find out its real position within the hierarchy of rules and also to precise its transposition into the different member state's legislation. Afterwards the two main parts exclusively concern the product liability in the french internal law. The fist part relates to define the notion of product liability, which possesses its proper characteristics and must to be distinguished from other similar notions, like regime of responsibility and its juridical obligations. Moreover, this same notion has got its proper scope of law and has to be carefully defined, that is to say the things which can be considered as a product, the person that are victims and responsible, and the damages concerned by the new dispositions. The second part deals with the regime of product responsibility itself. Primary, it depends on specific conditions which constitute the legal system, although the litigants are allowed to organise it through conventional modifications. Secondly, in case of interference of a foreign element during a litigation, its implement involves studying the international competence of law and jurisdiction. The specificity of this regime means that the victim's claim possesses a special jurisdictional treatment for the court. At last, both the producers' risks and the extent of reparation lead to a special study of the collective measure of compensation by of third party
Cadiergue, Hélène. "Murissement de matières actives agrochimiques en suspensions concentrées". Aix-Marseille 3, 1992. http://www.theses.fr/1992AIX3A014.
Texto completoBrunol, Emmanuelle. "Généralisation des mécanismes de détection de composés de type organophosphonate en surface de capteurs de gaz à base de dioxyde d'étain". Besançon, 2005. http://www.theses.fr/2005BESA2076.
Texto completoMertens, Johann. "Conception d'un microlevier et analyse de sa réactivité avec un gaz : application à la réalisation d'un capteur de détection de florure d'hydrogène". Dijon, 2003. http://www.theses.fr/2003DIJOS055.
Texto completoThe objective of this work was the development of an hydrogen fluoride (HF) sensor by mechanical response of SiOx and Si3N4 microcantilevers that have typical dimensions of 2003́00́. 5 æm. Their fabrication uses thin films coating, lithography and reactive ion etching processes. A XPS, SIMS, AFM study of the dielectric layers shows a lateral etching orientation for SiOx and a transversal one for Si3N4. A gold layer (not reactive) is deposited on one face of the cantilever, making it sensitive to both temperature and surface stress. The sensitivity of the system to the temperature, pressure and humidity has been defined. SiOx and Si3N4 layers reactivity toward HF was measured in term of deflection and frequency resonance variation. The response of the sensor depends on the amount of HF introduced into the cell. The gas is then detected in term of irreversible deflection until 260 ppb. The influence of the surface roughness and stoichiometry of the reactive layers was demonstrated
Lemoine, Alan. "Gazéification pyrolytique de la graine de canola par lit jaillissant par plasma". Sherbrooke : Université de Sherbrooke, 2001.
Buscar texto completoTournier, Carole. "Interactions texture-flaveur : mécanismes physico-chimiques ou mécanismes cognitifs ? : application à un gel laitier onctueux". Dijon, 2006. http://www.theses.fr/2006DIJOS062.
Texto completoThe present work aimed at studying sensory interactions between texture, taste and aroma, in relation with the perception of creaminess, an indicator of food quality. A first step consisted in defining the creaminess concept. This study highlighted three groups of consumers related to the texture, taste and fattiness of dairy products. The second step consisted in studying sensory interactions between texture, taste and aroma. Binary interactions were then studied in a reciprocal way using a consumers’panel. Physico-chemical complementary studies were finally developed in an attempt to better understand the origin of the observed interactions. Texture modified perceived taste and tended to modify aroma perception, via physico-chemical mechanisms principally. Conversely, taste and aroma perception did not affect texture perception. Finally, a reciprocal taste – aroma interaction, probably from cognitive origin, was observed
Slassi, Abdelmalik. "Synthèse stéréosélective et énantiosélective d'hétérocycles oxygénés disubstitués : application à la synthèse de produits naturels". Lyon 1, 1990. http://www.theses.fr/1990LYO10192.
Texto completoMusavu-Ndob, Aïchatou. "Mesures, modélisation, prédiction des propriétés physico-chimiques dans les aliments à l'aide d'un modèle thermodynamique : application aux produits carnés et aux produits laitiers". Thesis, Clermont-Ferrand 2, 2016. http://www.theses.fr/2016CLF22682/document.
Texto completoThe development of food process simulators is actually limited by absence of tools that can predict de evolution of the physical-chemical properties (pH, aw, Eh) in food. Food are generallymulticomponent medias (including water, organic solvents, dissolved solids, dissolved gases, ionic species, macromolecules), and these properties are essential to characterize technological, sanitary and organoleptic qualities. However, these physical-chemical properties change during transformation or preservation process. The prediction of these properties requires the determination of chemical potentials. Thermodynamic approach is used to predict pH and water activity of meat and dairy products in different condition encountered in the food industry. Based on the model ULPDHS developed by Achard in 1992 for liquid medias, this work required the creation of fictive molecule who have the same behavior as modeled food. Consistency between the experimental data and the predicted data is very satisfactory, the thermodynamic model correctly predict the pH and aw of different products studied. The integration of the thermodynamic model in a process simulator requires the creation of a mimetic neural network. Therefore, was developed a neural network whose outputs are identical to the output of the thermodynamic model. So it is possible to integrate the results of thermodynamic models in a process simulator without too lengthen the time simulations. The results obtained in this work can be an important aid to the formulation of new products. The model is completely predictive and it is possible to determine the effect of a change in the composition of the feed on the pH and aw
Seyni, Abdoulaye. "Propriétés physico-chimiques et d'usage de matériaux composites à charge dégradable produits par co-broyage". Phd thesis, Toulouse, INPT, 2008. http://oatao.univ-toulouse.fr/7820/1/seyni.pdf.
Texto completoNtonga-Bomba, Serge Vincent. "Le contrôle de l'exportation des produits chimiques dangereux à usage agroalimentaire vers le Tiers monde". Paris 2, 1992. http://www.theses.fr/1992PA020015.
Texto completoIn agriculture and fight against insects developing countries using numerous chemical products some of which are harmful and forbidden in developed countries. These pesticides are extremely damaging both to the population and to the environment of the third world. Nuclear waste exported to these countries is also a big issue. Our research aims to denounce this scandalous practice and collect various international laws existing in disparate way over this much debated sector in oder to propose methods and strategies adapted to developing countries. The poor countries should use methods that guarranty simultanously the quality of foodstuffs, the consumer health and the environment integrity
Haloui, Abdallah. "Libération dans l'eau des produits chimiques utilisés pour la préservation du bois : modélisation et expérimentation". Saint-Etienne, 1995. http://www.theses.fr/1995STET4017.
Texto completoSeyni, Abdoulaye Le Bolay Nadine. "Propriétés physico-chimiques et d'usage de matériaux composites à charge dégradable produits par co-broyage". Toulouse : INP Toulouse, 2009. http://ethesis.inp-toulouse.fr/archive/00000841.
Texto completoRamette, Quentin. "Construction de souches cellulolytiques de Clostridium acetobutylicum pour la production de produits chimiques de commodité". Electronic Thesis or Diss., Toulouse, INSA, 2022. http://www.theses.fr/2022ISAT0053.
Texto completoThe overarching objective of the PhD is to construct and select a cellulolytic C. acetobutylicum bacterium which is able to grow on pretreated lignocellulosic biomass. Modification of C. acetobutylicum's genome will be performed using the synthetic biology tools (suicide vectors coupled to genome editing with an inducible CRISPR-Cas9 system) previously developed in the EAD3 at TBI (Foulquier et al. 2019). The most efficient mutants for the different “industrial lignocellulosic feedstocks” will be selected and characterized from a biochemical and molecular point of view. The identified key proteins will also be characterized by overproducing them by E. coli BL21 DE3. This approach should allow a better understanding of the parameters governing cellulosome efficiency and will improve the fundamental knowledge on the mechanism of lignocellulosic biomass hydrolysis by the C. acetobutylicum cellulosome. References Foulquier, Celine, Ching-Ning Huang, Ngoc-Phuong-Thao Nguyen, Axel Thiel, Tom Wilding-Steel, Julie Soula, Minyeong Yoo, et al. 2019. “An Efficient Method for Markerless Mutant Generation by Allelic Exchange in Clostridium acetobutylicum and Clostridium saccharobutylicum Using Suicide Vectors.” Biotechnology for Biofuels 12 (1): 31. https://doi.org/10.1186/s13068-019-1364-4
Dallot, Constantin. "Perturbation de la fonction thyroïdienne : mise en place d’une stratégie de criblage des produits chimiques". Electronic Thesis or Diss., Nice, 2015. http://www.theses.fr/2015NICE4135.
Texto completoWhereas disruption of thyroid hormone signaling by environmental chemicals is a growing concern, identifying thyroid toxicants in early screening studies remains a challenge. Indeed, several different molecular events can initiate a such disruption of the Hypothalamus-Pituitary-Thyroid (HPT) axis. Thus, the detection of thyroid toxicants implies to conduct systematically an important battery of in vitro assays, or long in vivo studies. In the aim to simplify the procedure for the screening of all the possible mode of actions (MoAs) involved, we assessed three models for their suitability to detect in a short term different thyroid toxicants by using changes in gene expression. We identified the possibility of discriminating thyroid toxicants from compounds that do not alter thyroid function, by using this approach, in a 7-day adult male rat assay. Regarding in vitro testing, we have established the proof of concept of discriminating direct-acting thyroid toxicants from compounds that do not affect thyroid function, on the basis of up-regulated expression of a set of genes as criteria of positivity, in an early screening in vitro assay based on PCCl3 rat thyroid cells. We also confirmed the relevance of the use of alginate-embedded cryopreserved hepatocytes (LiverbeadsTM) for the screening of liver-mediated thyroid toxicity in rodents. The present work allowed the identification of three models suitable for the early screening of the disruption of the thyroid function. Such detection of multiple toxic MoAs in a short term relies on the use of gene expression as main or unique endpoint
Dallot, Constantin. "Perturbation de la fonction thyroïdienne : mise en place d’une stratégie de criblage des produits chimiques". Thesis, Nice, 2015. http://www.theses.fr/2015NICE4135/document.
Texto completoWhereas disruption of thyroid hormone signaling by environmental chemicals is a growing concern, identifying thyroid toxicants in early screening studies remains a challenge. Indeed, several different molecular events can initiate a such disruption of the Hypothalamus-Pituitary-Thyroid (HPT) axis. Thus, the detection of thyroid toxicants implies to conduct systematically an important battery of in vitro assays, or long in vivo studies. In the aim to simplify the procedure for the screening of all the possible mode of actions (MoAs) involved, we assessed three models for their suitability to detect in a short term different thyroid toxicants by using changes in gene expression. We identified the possibility of discriminating thyroid toxicants from compounds that do not alter thyroid function, by using this approach, in a 7-day adult male rat assay. Regarding in vitro testing, we have established the proof of concept of discriminating direct-acting thyroid toxicants from compounds that do not affect thyroid function, on the basis of up-regulated expression of a set of genes as criteria of positivity, in an early screening in vitro assay based on PCCl3 rat thyroid cells. We also confirmed the relevance of the use of alginate-embedded cryopreserved hepatocytes (LiverbeadsTM) for the screening of liver-mediated thyroid toxicity in rodents. The present work allowed the identification of three models suitable for the early screening of the disruption of the thyroid function. Such detection of multiple toxic MoAs in a short term relies on the use of gene expression as main or unique endpoint
Evon, Philippe Rigal Luc. "Nouveau procédé de bioraffinage du tournesol plante entière par fractionnement thermo-mécano-chimique en extrudeur bi-vis étude de l'extraction aqueuse des lipides et de la mise en forme du raffinat en agromatériaux par thermomoulage /". Toulouse : INP Toulouse, 2008. http://ethesis.inp-toulouse.fr/archive/00000668.
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