Literatura académica sobre el tema "Plasmodium falciparum – Dormance"
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Artículos de revistas sobre el tema "Plasmodium falciparum – Dormance"
Maslachah, Lilik, Yoes Prijatna Dachlan, Chairul A. Nidom y Loeki Enggar Fitri. "Induction of Plasmodium falciparum strain 2300 dormant forms by artemisinin". Universa Medicina 34, n.º 1 (26 de febrero de 2016): 25. http://dx.doi.org/10.18051/univmed.2015.v34.25-34.
Texto completoGrobler, Lizette, Marina Chavchich, Richard K. Haynes, Michael D. Edstein y Anne F. Grobler. "Assessment of the Induction of Dormant Ring Stages in Plasmodium falciparum Parasites by Artemisone and Artemisone Entrapped in Pheroid VesiclesIn Vitro". Antimicrobial Agents and Chemotherapy 58, n.º 12 (6 de octubre de 2014): 7579–82. http://dx.doi.org/10.1128/aac.02707-14.
Texto completoDembélé, Laurent, Jean-François Franetich, Valérie Soulard, Nadia Amanzougaghene, Shahin Tajeri, Teun Bousema, Geert-Jan van Gemert et al. "Chloroquine Potentiates Primaquine Activity against Active and Latent Hepatic Plasmodia Ex Vivo: Potentials and Pitfalls". Antimicrobial Agents and Chemotherapy 65, n.º 1 (19 de octubre de 2020): e01416-20. http://dx.doi.org/10.1128/aac.01416-20.
Texto completoChen, Nanhua, Alexis N. LaCrue, Franka Teuscher, Norman C. Waters, Michelle L. Gatton, Dennis E. Kyle y Qin Cheng. "Fatty Acid Synthesis and Pyruvate Metabolism Pathways Remain Active in Dihydroartemisinin-Induced Dormant Ring Stages of Plasmodium falciparum". Antimicrobial Agents and Chemotherapy 58, n.º 8 (9 de junio de 2014): 4773–81. http://dx.doi.org/10.1128/aac.02647-14.
Texto completoChavchich, Marina, Karin Van Breda, Kerryn Rowcliffe, Thierry T. Diagana y Michael D. Edstein. "The Spiroindolone KAE609 Does Not Induce Dormant Ring Stages in Plasmodium falciparum Parasites". Antimicrobial Agents and Chemotherapy 60, n.º 9 (13 de junio de 2016): 5167–74. http://dx.doi.org/10.1128/aac.02838-15.
Texto completoCheng, Qin, Dennis E. Kyle y Michelle L. Gatton. "Artemisinin resistance in Plasmodium falciparum: A process linked to dormancy?" International Journal for Parasitology: Drugs and Drug Resistance 2 (diciembre de 2012): 249–55. http://dx.doi.org/10.1016/j.ijpddr.2012.01.001.
Texto completoTeuscher, Franka, Nanhua Chen, Dennis E. Kyle, Michelle L. Gatton y Qin Cheng. "Phenotypic Changes in Artemisinin-Resistant Plasmodium falciparum LinesIn Vitro: Evidence for Decreased Sensitivity to Dormancy and Growth Inhibition". Antimicrobial Agents and Chemotherapy 56, n.º 1 (10 de octubre de 2011): 428–31. http://dx.doi.org/10.1128/aac.05456-11.
Texto completoBouyer, Guillaume, Anne Cueff, Stéphane Egée, Justyna Kmiecik, Yelena Maksimova, Edyta Glogowska, Patrick G. Gallagher y Serge L. Y. Thomas. "Erythrocyte peripheral type benzodiazepine receptor/voltage-dependent anion channels are upregulated by Plasmodium falciparum". Blood 118, n.º 8 (25 de agosto de 2011): 2305–12. http://dx.doi.org/10.1182/blood-2011-01-329300.
Texto completoPolenzani, Ilaria, Lucrezia Lisco, Mariarosaria Cozzolino, Stefania Casolari, Stefania Valenti, Simone Fontijn, Andrea Uva, Andrea Uva y Federico Marchetti. "Quando la malaria tarda a farsi riconoscere: un’infezione da Plasmodium ovale". Medico e Bambino 41, n.º 6 (28 de junio de 2022): 381–85. http://dx.doi.org/10.53126/meb41381.
Texto completoDruilhe, Pierre, Philippe Brasseur, Catherine Blanc y Michael Makler. "Improved Assessment of Plasmodium vivax Response to Antimalarial Drugs by a Colorimetric Double-Site Plasmodium Lactate Dehydrogenase Antigen Capture Enzyme-Linked Immunosorbent Assay". Antimicrobial Agents and Chemotherapy 51, n.º 6 (26 de marzo de 2007): 2112–16. http://dx.doi.org/10.1128/aac.01385-06.
Texto completoTesis sobre el tema "Plasmodium falciparum – Dormance"
Platon, Lucien. "Étude de la résistance de Plasmodium falciparum et des phénotypes de dormance induite par l'artémisinine : du patient à la cellule". Electronic Thesis or Diss., Sorbonne université, 2023. http://www.theses.fr/2023SORUS054.
Texto completoPlasmodium falciparum is the causative agent of the most severe form of malaria. In 2022, the disease was responsible for 619,000 deaths and 247 million cases worldwide. P. falciparum has a complex life cycle in the mosquito vector and in the human host. Artemisinin and its derivatives are used in combination with partner drugs. Artemisinin-based combination therapies (ACT) are currently the most effective treatment available. Unfortunately, malaria control efforts are threatened by mutations in the Pfkelch13 gene of P. falciparum, which confer partial resistance to artemisinin. This resistance to artemisinin is also associated with a drug-induced dormancy phenotype, which allows a proportion of parasites to survive exposure to the drug. This thesis focuses on artemisinin resistance and drug-induced dormancy through a multidisciplinary approach. It combines public health, technical optimisation and basic research. As part of the public health work, we have detected the emergence of a new double mutant Pfkelch13-R622I resistant to artemisinin in patients in Eritrea. This mutant is associated with deletions in the Pfhrp2 and Pfhrp3 genes, reducing the performances of HRP2-based rapid diagnostic tests. These data highlight the urgency of developing new control strategies in the context of the emergence of artemisinin resistance across the African continent. An optimised version of the Ring-Stage Survival Assay, the main diagnostic tool used to detect artemisininresistant P. falciparum parasites, was developed. This optimisation allows for the simultaneous synchronisation of several P. falciparum strains with different genetic backgrounds, thus enabling multiple RSA tests to be performed in parallel in a reliable and reproducible manner. Finally, basic research focused on studying drug-induced dormancy as a mechanism of artemisinin resistance. We were able to demonstrate important changes in the metabolism of dormant ring stage parasites based on amino acid catabolism. We have also shown that dormancy can be induced by extracellular stress signals released by dying mature stage parasites. Finally, our data indicate that the synchronous early ring stage of a clonal parasite population exhibits high transcriptional diversity. All the data presented suggest that dormancy is a constitutive mechanism at P. falciparum ring stage, mediated by extracellular signals of an unknown nature and concentration, independent of Pfkelch13 genotypes. We are convinced this work may provide a basis for developing a new therapeutic strategy based on interfering with the parasite's extracellular communications
Galusic, Sandra. "MMV Malaria Box Activity Screening in Dormant Plasmodium falciparum Phenotypes". Scholar Commons, 2015. http://scholarcommons.usf.edu/etd/5687.
Texto completoFlaherty, Siobhan Marie. "Efficacy and Resistance Potential of JPC-3210 in Plasmodium falciparum". Scholar Commons, 2015. http://scholarcommons.usf.edu/etd/5832.
Texto completoDuvalsaint, Marvin Duvalsaint. "The Effects of Phytohormones and Isoprenoids in Dihydroartemisinin-induced Dormancy in the Erythrocytic Stages of Plasmodium falciparum". Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6495.
Texto completoCapítulos de libros sobre el tema "Plasmodium falciparum – Dormance"
Aigbiremo Oboh, Mary, Mamadou Ndiath, Olumide Ajibola, Kolapo Oyebola y Alfred Amambua-Ngwa. "Increased Trends of P. vivax in Sub-Saharan Africa: What Does it Mean for Malaria Elimination?" En Current Topics and Emerging Issues in Malaria Elimination. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.97189.
Texto completoH. Asakawa, Ami y Roman Manetsch. "A Comprehensive Review of 4(1H)-Quinolones and 4(1H)-Pyridones for the Development of an Effective Antimalarial". En Plasmodium Species and Drug Resistance [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.97084.
Texto completoCui, Liwang, Awtum Brashear, Lynette Menezes y John Adams. "Elimination of Plasmodium vivax Malaria: Problems and Solutions". En Current Topics and Emerging Issues in Malaria Elimination. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96604.
Texto completoJayakumar, Angelina y Zahir Osman Eltahir Babiker. "Malaria". En Tutorial Topics in Infection for the Combined Infection Training Programme. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198801740.003.0072.
Texto completoKepple, Daniel, Anthony Ford, Ebony Little, Gabrielle Kolesar, Beka R. Abagero, Ashley N. Blackwell, Swarnapali De Silva Indrasekara, Delenasaw Yewhalaw y Eugenia Lo. "From Genes to Biomarkers: Understanding the Biology of Malaria Gametocytes and Their Detection". En Genetic Polymorphisms - New Insights [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.99364.
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