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Artículos de revistas sobre el tema "Physiological"

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Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 29 de julio de 2024

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1

Brown, Ronald P., Michael D. Delp, Stan L. Lindstedt, Lorenz R. Rhomberg y Robert P. Beliles. "Physiological Parameter Values for Physiologically Based Pharmacokinetic Models". Toxicology and Industrial Health 13, n.º 4 (julio de 1997): 407–84. http://dx.doi.org/10.1177/074823379701300401.

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2

Chen, Wujun, Shuai Wang, Yudong Wu, Xin Shen, Shutan Xu, Zhu Guo, Renshuai Zhang y Dongming Xing. "The Physiologic Activity and Mechanism of Quercetin-Like Natural Plant Flavonoids". Current Pharmaceutical Biotechnology 21, n.º 8 (8 de julio de 2020): 654–58. http://dx.doi.org/10.2174/1389201021666200212093130.

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The term “vitamin P” is an old but interesting concept. Most substances in this category belong to the family of flavonoids. “Vitamin P” has also been used to define the activity of some flavonoids, including quercetin, myricetin, and rutin. According to experimental studies, the “quercetin-like natural plant flavonoids” are beneficial to the body due to their various physiological and pharmacological activities in large doses (5 μM in vitro, 50 mg/kg in mice and 100 mg/kg in rats). The physiologically achievable concentration is 10 to 100 nM, which is quite high and hard to achieve from a normal diet. Thus, the physiologic activity and mechanism of "vitamin P" are still not clear. It should be noted that the quercetin-like natural plant flavonoids are physiological co-factors of cyclooxygenases (COXs), which are the rate-limiting key enzymes of prostaglandins. These quercetin-like natural plant flavonoids can strongly stimulate prostaglandin levels at lower doses (10 nM in vitro and in 0.1 mg/kg in vivo in rats). Although these "vitamin P" substances are not original substances in the body, their physiological functions affect the body. This review is focused on the most compelling evidence regarding the physiologic role and mechanism of quercetin-like natural plant flavonoids, which may be useful in understanding the physiological functions of "vitamin P", with the goal of focusing on the role of flavonoids in human physiological health.

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3

Cavasin, Pedro Yuri, Wilson Vicente Souza Pereira y Heloisa Oliveira dos Santos. "Physiological quality of Capsicum chinense 'Adjuma' seeds during development". Bioscience Journal 39 (5 de mayo de 2023): e39075. http://dx.doi.org/10.14393/bj-v39n0a2023-64823.

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Once “bode” pepper plants (Capsicum) have continuous development and fructification, it is not possible to determine a specific season for seed physiologic maturation and harvest. This research aimed to evaluate physiological quality of “bode” pepper (Capsicum chinense 'Adjuma’) during fruit development and enzymes expression on seed germination. Manually extracted seeds were submitted to physiological tests being evaluated germination at first count (FC), final (G), and germination speed index (GSI), additionally, enzymatic analyses were carried. The lowest values for the physiological tests were observed for initial development stages. The greatest for FC, G and IVG were observed for seeds from fruits 70 days after anthesis (DAA). Superoxide dismutase enzyme has the highest values on seeds harvested at 49 DAA while malate dehydrogenase has more expression at 70 DAA. Catalase, alcohol dehydrogenase, and esterase have the higher expression at 63 DAA. The maturation stage influences bode pepper seed physiological quality, being seeds harvested at 70 DAA those with the better results on the evaluated parameters, thus, considered physiologically mature and the indicated time for harvest.

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4

Fiserova-Bergerova, Vera. "Extrapolation of physiological parameters for physiologically based simulation models". Toxicology Letters 79, n.º 1-3 (septiembre de 1995): 77–86. http://dx.doi.org/10.1016/0378-4274(95)03359-s.

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5

Pandey, Sandhya, Ravi Kumar Chittoria, Mohapatra Devi Prasad, Friji M.T., Dinesh Kumar Sivakumar y Bibilash Babu Suseela. "Conventional Palatoplasty Versus Physiological Palatoplasty". New Indian Journal of Surgery 7, n.º 2 (2016): 95–102. http://dx.doi.org/10.21088/nijs.0976.4747.7216.2.

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6

Verma, S. S. "Regression models in physiological research". Zeitschrift für Morphologie und Anthropologie 83, n.º 1 (1 de marzo de 2001): 129–38. http://dx.doi.org/10.1127/zma/83/2001/129.

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7

Shahnawaz, Fatima. "Spirituality and Psycho-Physiological Health". Global Journal For Research Analysis 3, n.º 2 (15 de junio de 2012): 190–91. http://dx.doi.org/10.15373/22778160/february2014/61.

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8

KRAUSE, E. "Cardiac energetics: Physiological and patho-physiological aspects". Journal of Molecular and Cellular Cardiology 23 (julio de 1991): S52. http://dx.doi.org/10.1016/0022-2828(91)90669-d.

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9

Steinberg, E. L., M. Nissan, K. Bar-Ilan, A. Menahem, R. Arbel y E. Luger. "PHYSIOLOGICAL CONSIDERATIONS IN FUNCTIONAL 3-D LUMBAR DIAGNOSIS: NON-PHYSIOLOGICAL TESTS". Journal of Musculoskeletal Research 07, n.º 01 (marzo de 2003): 25–38. http://dx.doi.org/10.1142/s0218957703000934.

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Lumbar spine function may be clinically assessed by subjective physician findings or by a more sophisticated mean such as 3-D dynamometric system. This system was developed to differentiate objectively between physiologic and non-physiological behavior of LBP patients. The same system is used, concurrently, to categorize the physiologic tests according to functional limitation. The four major parameters used for assessing spinal disability are: range of motion, maximal isometric torque, maximal velocity and maximal torque in the secondary axis. Six other independent parameters were used in order to assess non-cooperative or non-physiologic behavior. For the study, 108 non-symptomatic subjects and 595 LBP patients were tested. All patients had a physical examination before being tested on the dynamometric device (the IsoStation B-200). One hundred and ten patients were classified as non-physiological and 91 were classified in the gray zone. The results support the use of 3-D dynamometry to objectively classify the patient's performance reliability. The measured parameters are objective and reliable indicators of the patient's physical condition and credibility that should influence both the patient's assessment and treatment.

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10

Lagos, Leah M. "The Physiologically Gifted Child". Biofeedback 41, n.º 2 (1 de junio de 2013): 62–65. http://dx.doi.org/10.5298/1081-5937-41.2.06.

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The Physiologically Gifted Child model proposes that sensitive children can turn their vulnerability to stress into strength through physiological training. When the child's sensitivity is viewed as a physiologically modifiable trait, the child is less likely to engage in self-blame and more likely to engage in self-care strategies to manage emotions. The author emphasizes that cardiovascular reactivity is significantly higher in a child with physiological giftedness. Because the physiologically gifted child is wired to react more intensely to stress, he or she is unlikely to be able to reduce sensitivity without addressing its physiological origin. The author proposes biofeedback and self-care activities as methods to reduce a physiologically gifted child's vulnerability to stress while simultaneously allowing the child to benefit from his or her extraordinary gifts of feeling and perceiving. A description of a physiologically gifted child and optimal performance strategies illustrate this concept.

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11

Benenson, Frederick Charles. "Physiological Processes". American Biology Teacher 65, n.º 3 (1 de marzo de 2003): 222–25. http://dx.doi.org/10.2307/4451480.

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12

Duong, Timothy Q. "Physiological MRI". Open Neuroimaging Journal 5, Suppl 1 (4 de noviembre de 2011): 65. http://dx.doi.org/10.2174/1874440001105010065.

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13

Dedrick, Robert L. "Physiological pharmacokinetics." Drug Metabolism and Pharmacokinetics 5, n.º 4 (1990): 509–11. http://dx.doi.org/10.2133/dmpk.5.509.

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14

McDonald, Ian. "`PHYSIOLOGICAL PATRIOTS'?" International Review for the Sociology of Sport 34, n.º 4 (diciembre de 1999): 343–58. http://dx.doi.org/10.1177/101269099034004003.

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15

Morita, S. "Physiological monitoring". Current Opinion in Anaesthesiology 3, n.º 6 (diciembre de 1990): 886–90. http://dx.doi.org/10.1097/00001503-199012000-00012.

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16

Hawley, John A. "Physiological Genomics". Medicine & Science in Sports & Exercise 38, Supplement (mayo de 2006): 47. http://dx.doi.org/10.1249/00005768-200605001-00170.

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17

Hawley, John A. "Physiological Genomics". Medicine & Science in Sports & Exercise 38, Supplement (mayo de 2006): 47. http://dx.doi.org/10.1249/00005768-200605001-00311.

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18

Jacucci, Giulio, Stephen Fairclough y Erin T. Solovey. "Physiological Computing". Computer 48, n.º 10 (octubre de 2015): 12–16. http://dx.doi.org/10.1109/mc.2015.291.

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19

JONES, RONALD. "Physiological Pseudomyopia". Optometry and Vision Science 67, n.º 8 (agosto de 1990): 610–16. http://dx.doi.org/10.1097/00006324-199008000-00010.

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20

Markel, A. L. "Physiological genetics". Russian Journal of Genetics: Applied Research 4, n.º 4 (julio de 2014): 301–10. http://dx.doi.org/10.1134/s2079059714040054.

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21

Sørland, Svein Jan. "Physiological Murmurs". Acta Medica Scandinavica 182, n.º 2 (24 de abril de 2009): 137–46. http://dx.doi.org/10.1111/j.0954-6820.1967.tb11507.x.

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22

Fibiger, H. C. "Physiological relevance". Behavioural Pharmacology 7, n.º 7 (noviembre de 1996): 661???662. http://dx.doi.org/10.1097/00008877-199611000-00011.

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23

Long, Jeri. "Physiological Amputation". Journal of Vascular Nursing 33, n.º 2 (junio de 2015): 82. http://dx.doi.org/10.1016/j.jvn.2015.05.003.

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24

Pace-Schott, Edward F., Marlissa C. Amole, Tatjana Aue, Michela Balconi, Lauren M. Bylsma, Hugo Critchley, Heath A. Demaree et al. "Physiological feelings". Neuroscience & Biobehavioral Reviews 103 (agosto de 2019): 267–304. http://dx.doi.org/10.1016/j.neubiorev.2019.05.002.

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25

Reynolds, Matthew y Peter Langridge. "Physiological breeding". Current Opinion in Plant Biology 31 (junio de 2016): 162–71. http://dx.doi.org/10.1016/j.pbi.2016.04.005.

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26

BISCHOFF, K. "Physiological pharmacokinetics". Bulletin of Mathematical Biology 48, n.º 3-4 (1986): 309–22. http://dx.doi.org/10.1016/s0092-8240(86)90030-3.

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27

Piruzyan, L. A. "Physiological Metrology". Doklady Biological Sciences 404, n.º 1-6 (septiembre de 2005): 341–44. http://dx.doi.org/10.1007/s10630-005-0130-x.

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28

Van Hamme, Jonathan D., Ajay Singh y Owen P. Ward. "Physiological aspects". Biotechnology Advances 24, n.º 6 (noviembre de 2006): 604–20. http://dx.doi.org/10.1016/j.biotechadv.2006.08.001.

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29

Bischoff, Kenneth B. "Physiological pharmacokinetics". Bulletin of Mathematical Biology 48, n.º 3-4 (mayo de 1986): 309–22. http://dx.doi.org/10.1007/bf02459684.

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30

Gadian, David. "Physiological MRI". NMR in Biomedicine 7, n.º 1-2 (marzo de 1994): 1. http://dx.doi.org/10.1002/nbm.1940070102.

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31

Watanabe, Yuriko y Shutaro Takeda. "Why do I like Schumann more than Chopin? A Physiological Analysis of Pianists' Affinities for Composers". Empirical Musicology Review 18, n.º 1 (12 de enero de 2024): 2–16. http://dx.doi.org/10.18061/emr.v18i1.8385.

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Understanding students' physiological characteristics is essential in piano teaching. However, how can teachers in the field know what music suits their students physiologically? This paper explores a new theory in sport science called, "the Four-Stance Theory" to provide teachers with a simple yet practical method to understand students' physiological nature. A survey-based experiment with 20 research participants (10 male and 10 female pianists) was conducted. Research participants were physically tested for their physiological "Stance Types" to see if pianists' physiological characteristics can predict their preferences for certain composers' music. Chi-square tests of independence showed that Stance Type can indeed predict what type of composers they favor (p < .05); further, this simple 10-minute physical test could also predict what types of composer's works they feel most technically comfortable to perform (p < .01) and feel are easier to understand (p < .05). These results indicate that this remarkably simple method could effectively discern pianists' physiological nature and predict which composer's music suits them physiologically. The authors envision that this 10-minute test could be useful for bringing physiological preparedness to both teachers and students.

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32

Rasool, Aqil y Sanjay Verma. "Dhauti : A Physiological Healer in Human Physiological System". RESEARCH REVIEW International Journal of Multidisciplinary 6, n.º 9 (15 de septiembre de 2021): 60–66. http://dx.doi.org/10.31305/rrijm.2021.v06.i09.009.

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33

Lee, Joo Myung, Ki Hong Choi, Jonghanne Park, Doyeon Hwang, Tae-Min Rhee, Jinseob Kim, Jinhyoung Park et al. "Physiological and Clinical Assessment of Resting Physiological Indexes". Circulation 139, n.º 7 (12 de febrero de 2019): 889–900. http://dx.doi.org/10.1161/circulationaha.118.037021.

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34

Petr, J., I. Capouchová y M. Štolcová. "Physiological nature of overwintering oats forms". Plant, Soil and Environment 48, No. 7 (21 de diciembre de 2011): 285–92. http://dx.doi.org/10.17221/4371-pse.

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We evaluated the need for low temperatures (vernalization) and the photoperiodic reaction of three collections of winter oats (1. Pedarn, Maris Quest, Peniarth; 2. Gerald, Solva, Kymon, Pendragon; 3. Pewi, Silwi, Wiskas) in a comparison with spring oats varieties. All three collections of varieties showed little need for low temperatures, mostly as few as 10–20 days, which does not represent an obligatory need; this influence is only quantitative and constitutes no precondition for a passage of plants into the generative stage. Only in the case of the Maris Quest variety, the need for vernalization approached 30 days. As compared with the reaction of winter barley varieties that had and in some cases still have worse overwintering in the Czech Republic, the length of vernalization is equal. In the photoperiodic experiment, the reaction to a short autumn day turned out to be the critical condition for a possibility of autumn sowing and overwintering; in the case of these varieties, a short day inhibits the development until arrival of winter. We evaluated this reaction according to the length of the induction period. This period was only 10–15 days in the case of the spring oats Český žlutý, 30 days in the case of winter oats Maris Quest, 25 days for Pedarn, 20 days for Peniarth and 21 days for Pendra-gon; the induction period was 14–21 days in the case of varieties Gerald, Kymon and Solva. When compared with figures for winter barley, it had the longer photoperiodic induction period. The evaluated varieties of winter oats do not reach such a degree of a reaction to a short day, which manifests itself in their lower frosthardiness than that of winter barley. We verified that in provoking tests for frosthardiness, and also by lower critical values of temperatures for dying out of 50% of plants, the so-called LT 50.

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35

Kordialik-Bogacka, E. y A. Diowksz. "Physiological state of reused brewing yeast". Czech Journal of Food Sciences 31, No. 3 (22 de mayo de 2013): 264–69. http://dx.doi.org/10.17221/84/2012-cjfs.

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In brewing, yeast may be reused many times. A number of yeast repitchings differs significantly among the breweries. Adjusting the number of times a strain may be serially repitched is of great importance for quality and consistency of final products. The fermentative and physiological characteristics of the yeast culture used in successive laboratory scale fermentations were determined. Yeast physiological state was assessed by the measurement of the levels of intracellular carbohydrates. In our investigation there were not any detectable changes in yeast capacity to ferment. No significant variation in the production of flavour compounds was found either. However, intracellular glycogen and trehalose contents were dependant on the yeast strain, generation number and wort gravity. Nevertheless, an alteration in the yeast physiological condition during serial repitchings occurred in a different mode than in previous studies confirming that the impact of serial repitchings is strain and medium dependent to a large extent.  

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36

Morgun, V. V., I. Cakmak, V. V. Schwartau y L. M. Mykhalska. "Physiological peculiarities of sunflower boron nutrition". Fiziologia rastenij i genetika 52, n.º 3 (junio de 2020): 187–95. http://dx.doi.org/10.15407/frg2020.03.187.

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37

Abdullayevna, Ziyamuhammedova Sabohat. "PHYSIOLOGICAL FEATURES OF WOMEN'S SPORTS TRAINING". American Journal Of Biomedical Science & Pharmaceutical Innovation 3, n.º 12 (1 de diciembre de 2023): 31–35. http://dx.doi.org/10.37547/ajbspi/volume03issue12-06.

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This study explores the nuanced physiological features specific to women's sports training, examining the multifaceted factors that differentiate female athletes' physiological responses and adaptations during training. Delving into hormonal influences, biomechanical considerations, energy system utilization, and recovery patterns, this investigation elucidates the unique physiological attributes shaping training protocols tailored to women athletes. Understanding these distinctive physiological features is pivotal in optimizing training methodologies, injury prevention strategies, and performance outcomes in women's sports.

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38

Satwekar, Mahesh. "Renal Proteins Biomarkers: It's Physiological Significance". International Journal of Science and Research (IJSR) 13, n.º 2 (5 de febrero de 2024): 263–64. http://dx.doi.org/10.21275/sr24129134011.

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39

Thorson, Katherine R., Oana D. Dumitru, Wendy Berry Mendes y Tessa V. West. "Influencing the physiology and decisions of groups: Physiological linkage during group decision-making". Group Processes & Intergroup Relations 24, n.º 1 (30 de diciembre de 2019): 145–59. http://dx.doi.org/10.1177/1368430219890909.

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Many of the most important decisions in our society are made within groups, yet we know little about how the physiological responses of group members predict the decisions that groups make. In the current work, we examine whether physiological linkage from “senders” to “receivers”—which occurs when a sender’s physiological response predicts a receiver’s physiological response—is associated with senders’ success at persuading the group to make a decision in their favor. We also examine whether experimentally manipulated status—an important predictor of social behavior—is associated with physiological linkage. In groups of 5, we randomly assigned 1 person to be high status, 1 low status, and 3 middle status. Groups completed a collaborative decision-making task that required them to come to a consensus on a decision to hire 1 of 5 firms. Unbeknownst to the 3 middle-status members, high- and low-status members surreptitiously were told to each argue for different firms. We measured cardiac interbeat intervals of all group members throughout the decision-making process to assess physiological linkage. We found that the more receivers were physiologically linked to senders, the more likely groups were to make a decision in favor of the senders. We did not find that people were physiologically linked to their group members as a function of their fellow group members’ status. This work identifies physiological linkage as a novel correlate of persuasion and highlights the need to understand the relationship between group members’ physiological responses during group decision-making.

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40

Chiossi, Francesco, Yagiz Turgut, Robin Welsch y Sven Mayer. "Adapting Visual Complexity Based on Electrodermal Activity Improves Working Memory Performance in Virtual Reality". Proceedings of the ACM on Human-Computer Interaction 7, MHCI (11 de septiembre de 2023): 1–26. http://dx.doi.org/10.1145/3604243.

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Biocybernetic loops encompass users' state detection and system adaptation based on physiological signals. Current adaptive systems limit the adaptation to task features such as task difficulty or multitasking demands. However, virtual reality allows the manipulation of task-irrelevant elements in the environment. We present a physiologically adaptive system that adjusts the virtual environment based on physiological arousal, i.e., electrodermal activity. We conducted a user study with our adaptive system in social virtual reality to verify improved performance. Here, participants completed an n-back task, and we adapted the visual complexity of the environment by changing the number of non-player characters. Our results show that an adaptive virtual reality can control users' comfort, performance, and workload by adapting the visual complexity based on physiological arousal. Thus, our physiologically adaptive system improves task performance and perceived workload. Finally, we embed our findings in physiological computing and discuss applications in various scenarios.

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41

Olimjon O’g’li, Ochilov Himoyiddin, Mingturayev Dilshod Karimovich y Ibrohimova Asila Ikromovna. "PHYSIOLOGICAL APPEARANCE OF FATIGUE AND ITS TYPES, PHYSIOLOGICAL CHANGES IN THE BODY DURING REST AFTER MUSCLE WORK". European International Journal of Multidisciplinary Research and Management Studies 02, n.º 10 (11 de octubre de 2022): 256–59. http://dx.doi.org/10.55640/eijmrms-02-10-47.

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Today, everyone who is tired is on the move, so it works on everyone. That is, the work of the muscles is strained. At that time, we need to give the muscles a little rest. This article provides information about the physiological appearance of the muscles when they are tired, and the changes that occur in the muscles after they rest.

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42

Fisher, D. A. "Physiological variations in thyroid hormones: physiological and pathophysiological considerations". Clinical Chemistry 42, n.º 1 (1 de enero de 1996): 135–39. http://dx.doi.org/10.1093/clinchem/42.1.135.

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Abstract Thyroid hormone production is regulated via pituitary thyrotropin (TSH) modulation of thyroxine (T4) prohormone secretion by the thyroid gland and regulation of active triiodothyronine (T3) production in peripheral tissues via metabolic events influencing activities of the iodothyronine monodeiodinase enzyme systems. Control at both levels is developmentally regulated and modified in serious nonthyroidal illness (trauma, infection, cancer, metabolic diseases). Racial and gender differences are of little significance except for the effects of placental estrogens and chorionic gonadotropin during pregnancy. There is a circadian rhythm of TSH secretion, with peak values at the onset of sleep and nadir concentrations during the afternoon hours. Peak and nadir concentrations differ by approximately +/- 50%. The effect on circulating T4 and T3 concentrations is not significant because of the large size of the extrathyroidal T4 pool. In healthy subjects there is no significant impact of body weight, physical training, body habitus, posture, immobilization, exercise, or ambulatory status on thyroid function, and no significant geographic environmental variation. Nutrition also has a minimal impact except for variation in iodine intake. Subthreshold concentrations of iodine intake are associated with increased TSH secretion, goiter, increased thyroid iodine uptake, decreased T4 production, an increased T3/T4 secretion ratio, and an increased ratio of circulating T3/T4 concentrations. Excessive iodine intake can block thyroid hormone biosynthesis by inhibiting the enzymes involved in the biosynthetic process, resulting in reduced T4 secretion, increased TSH concentrations, goiter, and hypothyroidism if the iodine excess is chronic.

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43

Hsieh, Yu-Heng, Xue-Qin Guan, Chia-Hung Liao y Shyan-Ming Yuan. "Physiological-chain: A privacy preserving physiological data sharing ecosystem". Information Processing & Management 61, n.º 4 (julio de 2024): 103761. http://dx.doi.org/10.1016/j.ipm.2024.103761.

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44

HASHIM, WISSAM SAJID. "Physiological Disturbances Caused by Citalopram in Rats". Journal of Research on the Lepidoptera 51, n.º 2 (15 de mayo de 2020): 408–16. http://dx.doi.org/10.36872/lepi/v51i2/301107.

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45

Caldeira, C. M., M. L. M. de Carvalho, R. M. Guimarães y S. V. B: Coelho. "Physiological priming and pelleting of tobacco seeds". Seed Science and Technology 42, n.º 2 (1 de agosto de 2014): 180–89. http://dx.doi.org/10.15258/sst.2014.42.2.07.

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46

Norboyeva, Umida y Oybarchin Khurramova. "SALINITY AND PHYSIOLOGICAL CHARACTERISTICS OF SOYBEAN VARIETIES". American Journal Of Agriculture And Horticulture Innovations 03, n.º 02 (1 de febrero de 2023): 20–25. http://dx.doi.org/10.37547/ajahi/volume03issue02-04.

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The article presents the data obtained on the study of the effect of soil salinity on some physiological characteristics of different soybean varieties. A decrease in the rate of transpiration and total water content was found in all varieties under conditions of saline soils. Based on the given results, it was noted that the above indicators change in various degrees in the section of the varieties and are related to the soil salinity and biological and varietal properties of the varieties, as well as the level of tolerance to salt.

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47

Clarke, A. y P. Calow. "Evolutionary Physiological Ecology." Journal of Applied Ecology 25, n.º 2 (agosto de 1988): 748. http://dx.doi.org/10.2307/2403862.

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48

IBA, Toshiaki y Shigeki KUSHIMOTO. "Physiological protease inhibitors". Japanese Journal of Thrombosis and Hemostasis 17, n.º 3 (2006): 314–19. http://dx.doi.org/10.2491/jjsth.17.314.

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Kurachi, Yoshihisa. "[OPINION] Physiological Hierarchy". Drug Delivery System 29, n.º 5 (2014): 384. http://dx.doi.org/10.2745/dds.29.384.

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Zhevandrov, N. D. "Polarisation physiological optics". Uspekhi Fizicheskih Nauk 165, n.º 10 (1995): 1193. http://dx.doi.org/10.3367/ufnr.0165.199510d.1193.

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