Literatura académica sobre el tema "Phage library"
Crea una cita precisa en los estilos APA, MLA, Chicago, Harvard y otros
Consulte las listas temáticas de artículos, libros, tesis, actas de conferencias y otras fuentes académicas sobre el tema "Phage library".
Junto a cada fuente en la lista de referencias hay un botón "Agregar a la bibliografía". Pulsa este botón, y generaremos automáticamente la referencia bibliográfica para la obra elegida en el estilo de cita que necesites: APA, MLA, Harvard, Vancouver, Chicago, etc.
También puede descargar el texto completo de la publicación académica en formato pdf y leer en línea su resumen siempre que esté disponible en los metadatos.
Artículos de revistas sobre el tema "Phage library"
Farquharson, Emma L. y Sam R. Nugen. "Enterobacteria Phage Ac3's Genome Annotation and Host Range Analysis Against the ECOR Reference Library". PHAGE 3, n.º 3 (1 de septiembre de 2022): 165–70. http://dx.doi.org/10.1089/phage.2022.0008.
Texto completoPetrenko, V. A., G. P. Smith, M. M. Mazooji y T. Quinn. "α-Helically constrained phage display library". Protein Engineering, Design and Selection 15, n.º 11 (noviembre de 2002): 943–50. http://dx.doi.org/10.1093/protein/15.11.943.
Texto completoSaggio, I. y R. Laufer. "Biotin binders selected from a random peptide library expressed on phage". Biochemical Journal 293, n.º 3 (1 de agosto de 1993): 613–16. http://dx.doi.org/10.1042/bj2930613.
Texto completoWen, Jianxin y Kunpeng Yuan. "Phage Display Technology, Phage Display System, Antibody Library, Prospects and Challenges". Advances in Microbiology 11, n.º 03 (2021): 181–89. http://dx.doi.org/10.4236/aim.2021.113013.
Texto completoDing, Yan-Li, Mei-Yun Liu, Wei Han, Sheng-Li Yang, Hui Liu y Yi Gong. "Application of Phage-displayed Single Chain Antibodies in Western Blot". Acta Biochimica et Biophysica Sinica 37, n.º 3 (1 de marzo de 2005): 205–9. http://dx.doi.org/10.1093/abbs/37.3.205.
Texto completoGillespie, James W., Liping Yang, Laura Maria De Plano, Murray A. Stackhouse y Valery A. Petrenko. "Evolution of a Landscape Phage Library in a Mouse Xenograft Model of Human Breast Cancer". Viruses 11, n.º 11 (26 de octubre de 2019): 988. http://dx.doi.org/10.3390/v11110988.
Texto completoBrichta, J., H. Vesela y M. Franek. "Production of scFv recombinant fragments against 2,4-dichlorophenoxyacetic acid hapten using naďve phage library". Veterinární Medicína 48, No. 9 (30 de marzo de 2012): 237–47. http://dx.doi.org/10.17221/5776-vetmed.
Texto completoDaniele, Sblattero, Not Tarcisio, Marzari Roberto y Bradbury Andrew. "PHAGE ANTIBODY LIBRARY FROM CELIAC DISEASE PATIENT". Journal of Pediatric Gastroenterology & Nutrition 28, n.º 5 (mayo de 1999): 568. http://dx.doi.org/10.1097/00005176-199905000-00118.
Texto completoBarchan, D., M. Balass, M. C. Souroujon, E. Katchalski-Katzir y S. Fuchs. "Identification of epitopes within a highly immunogenic region of acetylcholine receptor by a phage epitope library." Journal of Immunology 155, n.º 9 (1 de noviembre de 1995): 4264–69. http://dx.doi.org/10.4049/jimmunol.155.9.4264.
Texto completoDuplessis, Martin, Céline M. Lévesque y Sylvain Moineau. "Characterization of Streptococcus thermophilus Host Range Phage Mutants". Applied and Environmental Microbiology 72, n.º 4 (abril de 2006): 3036–41. http://dx.doi.org/10.1128/aem.72.4.3036-3041.2006.
Texto completoTesis sobre el tema "Phage library"
Bell, Matthew John. "Phage display of a cDNA library from Arabidopsis thaliana". Thesis, Coventry University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393652.
Texto completoKeklikian, Artine. "Construction of a Synthetic Human VL Phage Display Library and Isolation of Potential Neuropilin-1-specific VL Therapeutics from the Library". Thèse, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/20197.
Texto completoClayton, Ruth. "Generation and characterisation of human sperm antibodies by combinatorial phage display library technology". Thesis, University of Sheffield, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286988.
Texto completoHald, Rikke. "Generation and characterisation of a naive human antibody phage display library : a resource for clinically relevant reagents /". Cph. : Department of Pharmacology, The Danish University of Pharmaceutical Sciences, 2004. http://www.dfh.dk/phd/defences/rikkehald.htm.
Texto completoPrendergast, D. "Discovery of tumour necrosis factor receptor-1 (p55) binding peptides using a phage display library". Thesis, Queen's University Belfast, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368468.
Texto completoSaxena, Abhishek. "Construction of immune scFv M13 phage display library and isolation of anti-glycan monoclonal antibodies". Thesis, University of Aberdeen, 2013. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=203295.
Texto completoLim, Theam Soon [Verfasser]. "Parameters affecting phage display library design for improved generation of human antibodies / Theam Soon Lim". Berlin : Freie Universität Berlin, 2009. http://d-nb.info/1023748355/34.
Texto completoCortini, Andrea. "Serum profiling and autoantibodies identification in Multiple Sclerosis using epitope and CSF IgG phage display libraries". Doctoral thesis, Università degli studi di Trieste, 2009. http://hdl.handle.net/10077/3073.
Texto completoMultiple sclerosis (MS) is considered the prototype of inflammatory autoimmune diseases of the central nervous system (CNS). The typical feature of the disease is the plaques of demyelination. The evolution of the plaque lesion in MS implicates an inflammatory phase followed by a recovery of functional myelin; a second step is the chronic progressive disease with axonal loss. The earlier phase of MS may be mediated by an autoimmune reaction. Whereas the role of T cells in MS pathogenesis is well established, the role of B cells and autoantibodies in demyelination and plaque formation is still unresolved. However several evidences suggest a contribute of autoantibodies in MS pathogenesis. B cells and myelin specific autoantibodies are present in the sclerosis plaques, and there is an increased production of immunoglobulin (Ig) in the cerebrospinal fluid (CSF) of more than 90% of MS patients . Typically these Ig present an oligoclonal pattern and sequencing of oligoclonal IgG showed extensive somatic mutations suggesting B cell clonal expansion and a specific antigen-driven immune response. The most extensively studied putative autoantigens are components of CNS myelin (myelin basic protein MBP, proteolipid protein PLP, myelin oligodendrocyte glycoprotein MOG). The autoantibodies in MS recognize both linear and conformational epitopes, but at present the conformational epitopes of myelin proteins have not been identified. For example, in MS, the T-cell receptors of autoreactive T lymphocytes recognize various peptides of the MBP, and, in EAE, the anti-MOG antibodies recognize only conformational epitopes. Furthermore, the progression of MS is accompanied by the decline of primary T-cell autoreactivity and by the concurrent emergence of neo-autoreactivity (epitope spreading). However recent investigation have showed that no myelin antigens, like neuron-specific enolase (NSE), retinal arrestin, beta-arrestin, may also have a role in MS pathogenesis. Autoimmunity against these antigens may be linked to neurodegeneration, defective remyelination, and predisposition to uveitis in multiple sclerosis. Several strategies, involving the phage display technology, have been employed in the attempt to discover the antigen that drives the immune response in MS. A first strategy depends on the cloning of IgG repertoire of MS patients in a phage display library screened with brain sections or known antigens. Another strategy involves large phage display libraries of random peptides screened with IgG of CSF in order to identify peptides recognized by antibodies present in CSF of MS patients. Phage display is a technique which involves the coupling of phenotype to genotype in a selectable format. It has been extensively used in molecular biology to study protein-protein interactions and to select antibodies against a wide range of different antigens. In this project we have proposed: 1. to study the autoimmune response in MS by using the phage display for the expression of antibodies involved in the disease. We wanted to make a ScFv library from B cells of CSF of different multiple sclerosis patients, to employ as tool to select a phage display Human Brain cDNA library for the identification of new antigens recognized by the immune sistem in MS patients. 2. To produce single gene mini library of putative antigens (MBP,PLP, MOG) for the generation of epitope chips to use for serotyping the immune response in different patients 3. To investigate the feasibility to use a single gene phage display mini-library as tool for epitope mapping (both linear and conformational) of novels autoantigens 4. To investigate the role of NSE(neuron specific enolase), a new possible no myelin autoantigen in multiple sclerosis, in the pathogenesis of the disease and the usefulness as possible diagnostic marker. Results: Scope 1 B-cells from liquor of two MS patients were centrifuged and the total RNA was extracted from the pellets. Total RNA was retrotranscripted and variable region of heavy and light chain of the antibodies were amplified by PCR. Heavy chain and light chain were assorted and assembled before to be cloned in the phagemid vector pDAN 5. A 2x104 independent clones library was obtained and analyzed by PCR and fingerprinting. A diversity of 30,8% for heavy chain and 72,7% for light chain was established. ScFv library was used to select a phage display Human Brain cDNA library. 17 clones with an high reactivity were obtained and after sequencing 6 clones on 17 have shown to be the same antigen(antigen A ); the reactivity on other two antigens obtained with the selection (antigen B and C) of CSF from 18 MS patients and 16 patients with other neurological disease (OND) was tested by ELISA to evaluate diagnostic value of this protein. The results shown that SM response was statistically different from OND response; the ELISA test gave a specificity of 94,12% and a significance of 53,85 %. The reactivity for the antigen B was also evaluated on sera of MS patients and controls. The MS response was statistically different from OND response and shown a specificity of 97,44% and a significance of 58,62 %. Scope 2&3 We have generated three single gene mini libraries of the major antigens in MS (MBP, MOG and PLP); cDNA of each gene was obtained by RT-PCR and after fragmentation cloned in a phagemid vector (pEP1) to obtain a mini-library for each gene. We have obtained a 2x105 for MBP, 2.4x104 for MOG and 1.6x106 for PLP independent clones library. MBP and MOG libraries were characterized by PCR and fingerprinting. Sequencing analysis shown that the entire MBP transcript variant 7 mRNA (664-1177 nt) and MOG isoform alpha 1 mRNA (262-918 nt) were represented in the respective library. To testing the capacity of selecting a single epitope from our libraries, we have performed a selection test with a commercial monoclonal antibody that recognize MBP 82-98 epitope; after three selection panning all selected clones contain the nucleotidic sequence 906- 956 nt (MBP transcript variant 7 mRNA) which encodes the immunogenic epitope recognized by the monoclonal antibody. Scope 4 The reactivity of sera from 31 MS patients and 14 healthy controls was tested by ELISA on NSE ; statistical analysis of the results shown that the two populations were significantly different.
XXI Ciclo
1981
Bosompem, Amma N. "Isolation of an anti-CD20 single chain variable fragment from a naïve human phage-scFv library". Connect to this title online, 2007. http://etd.lib.clemson.edu/documents/1202410076/.
Texto completoMarson, Lorena. "Phage-display epitope library development for biomarkers identification in autoimmune diseases of the Central Nervous System". Doctoral thesis, Università degli studi di Trieste, 2012. http://hdl.handle.net/10077/7405.
Texto completoThe principal aim of my PhD was the setting of a protocol for the creation of phage libraries to display cDNA fragments encoding real ORF sequences, that could correspond to potential epitopes. A similar phage display library contains all the potential ORF repertoire of a cell or tissue. This tool can be specially used in the study of autoimmune diseases to perform different kind of analysis, such as the identification of epitopes involved in pathological reaction, the comparison between healthy and pathological conditions, or between different pathological conditions. A complex protocol was developed. It provides for: cDNA normalization, cDNA fragmentation to obtain peptides with useful size, and ORF enrichment to obtain really coding fragments. With this system we have created a epitopes library from Human brain mRNA.
Il principale obiettivo del mio lavoro di ricerca è la messa a punto di un protocollo per la costruzione di librerie fagiche di frammenti di cDNA codificanti per frammenti ORF, e che quindi potrebbero corrispondere a potenziali epitopi. Questo tipo di librerie contengono, potenzialmente, tutto il repertorio ORF di una cellula o di un tessuto e possono quindi essere utilizzate nello studio di malattie autoimmuni al fine di identificare nuovi epitopi coinvolti nella risposta immunitaria, di fare un confronto tra lo stato patologico e quello sano o tra diverse condizioni patologiche. Abbiamo quindi messo a punto un complesso protocollo che prevede: la normalizzazione del cDNA, la sua frammentazione per ottenere peptidi di dimensioni opportune, e l'arricchimento in frammenti realmente codificanti. Con questo sistema abbiamo realizzato una libreria di epitopi a partire da mRNA di cervello umano.
XXIV Ciclo
1984
Libros sobre el tema "Phage library"
Tim, Clackson y Lowman Henry B, eds. Phage display: A practical approach. Oxford: Oxford University Press, 2004.
Buscar texto completoClarke, Dougan & Associates. Library automation study: Feasibility phase : final report. [Waterloo, Ont.]: Clarke, Dougan & Associates, 1987.
Buscar texto completoBeaumont, Jane. Bancroft Public Library: Needs assessment for library automation, APSL phase I report. [Bancroft, Ont.]: The Library, 1987.
Buscar texto completoConsultants, Woods Gordon Management. Barrie Public Library facilities development study, phase II. [Toronto: Woods Gordon, 1989.
Buscar texto completoCrawford, Walt. Patron Access Project, phase I. Stanford, Calif: Research Libraries Group, Research & Development Division, 1986.
Buscar texto completoCrawford, Walt. Patron Access Project, phase I. Stanford, Calif: Research Libraries Group, Research & Development Division, 1986.
Buscar texto completoResearch Libraries Group. Research & Development Division., ed. Patron access project, phase I. Stanford, Calif: Research Libraries Group, Research & Development Division, 1986.
Buscar texto completoAssociates, Fox Jones &. Wainfleet Township Public Library facility feasibility study: Phase II report. [Wainfleet, Ont: Wainfleet Township Public Library, 1991.
Buscar texto completoFox Jones & Associates. Wainfleet Township Public Library needs assessment study: Phase I report. [Wainfleet, Ont: WTPL, 1990.
Buscar texto completoLibrary, Fort Erie Public y Information Technology Strategy Inc, eds. Fort Erie Public Library automation feasibility study: Phase 1 report. [Toronto, Ont: Information Technology Strategy Inc., 1988.
Buscar texto completoCapítulos de libros sobre el tema "Phage library"
Midoro-Horiuti, Terumi y Randall M. Goldblum. "Epitope Mapping with Random Phage Display Library". En Methods in Molecular Biology, 477–84. Totowa, NJ: Humana Press, 2014. http://dx.doi.org/10.1007/978-1-62703-992-5_28.
Texto completoWeil, Clifford F. y Thomas E. Bureau. "Construction of a Genomic Library in Lambda Phage". En The Maize Handbook, 595–98. New York, NY: Springer New York, 1994. http://dx.doi.org/10.1007/978-1-4612-2694-9_105.
Texto completoFagerlund, Annette, Astrid Hilde Myrset y Mari Ann Kulseth. "Construction of a Filamentous Phage Display Peptide Library". En Methods in Molecular Biology, 19–33. Totowa, NJ: Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-673-3_2.
Texto completoSamoylova, Tatiana I. y Bruce F. Smith. "Identification of Cell Targeting Ligands Using Random Peptide-Presenting Phage Libraries". En Genetic Library Construction and Screening, 209–31. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-642-56408-6_11.
Texto completoAddepalli, Balasubrahmanyam, Suryadevara Rao y Arthur G. Hunt. "Phage Display Library Screening for Identification of Interacting Protein Partners". En Methods in Molecular Biology, 147–58. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-2175-1_13.
Texto completoOmar, Noorsharmimi y Theam Soon Lim. "Construction of Naive and Immune Human Fab Phage-Display Library". En Methods in Molecular Biology, 25–44. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7447-4_2.
Texto completoChen, Peng-Hsun Chase y Wenshe Ray Liu. "The Construction of a Genetically Encoded, Phage-Displayed Cyclic-Peptide Library". En Methods in Molecular Biology, 219–30. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1617-8_17.
Texto completoZhu, Kejia, Shanshan Wu, Hailing Ma, Ke Wu, Wenhui Ji, Shifei Yang, Xiaolan Fu et al. "Screening of Ochratoxin a mimotopes in phage random 7-peptide library". En Advances in Civil Engineering and Environmental Engineering, Volume 2, 45–49. London: CRC Press, 2023. http://dx.doi.org/10.1201/9781003383031-8.
Texto completoSummer, Elizabeth J. "Preparation of a Phage DNA Fragment Library for Whole Genome Shotgun Sequencing". En Methods in Molecular Biology, 27–46. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-565-1_4.
Texto completoJakob, Valentin, Saskia Helmsing, Michael Hust y Martin Empting. "Restriction-Free Construction of a Phage-Presented Very Short Macrocyclic Peptide Library". En Methods in Molecular Biology, 95–113. New York, NY: Springer US, 2019. http://dx.doi.org/10.1007/978-1-4939-9853-1_6.
Texto completoActas de conferencias sobre el tema "Phage library"
Spitzer, S. G., P. Usharani, A. D. Roser, C. K. Kasper y S. G. Bajaj. "THE CATALYTIC TRIAD RESIDUES (HIS221, ASP269, SER365) AND THE BINDING POCKET RESIDUE (ASP359) IN FACTOR IXBm ELSINORE (IXBmLE) ARE NOT ALTERED". En XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644071.
Texto completoJones, Kelvin M., Rajeev Samant, Shree Singh y Deepa Bedi. "Abstract 1078: Identification of peptides binding to mesenchymal subtype breast cancer from phage display peptide library". En Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-1078.
Texto completoBezerra, Marcus, Andrea Maranhao, Igor Studart, Larissa Pontes, Marcela Fonseca y Gilvan Furtado. "Construction of a scFv library using directed evolution for rituximab-based therapies: using phage display towards antibody affinity maturation". En IV International Symposium on Immunobiologicals & VII Seminário Anual Científico e Tecnológico. Instituto de Tecnologia em Imunobiológicos, 2019. http://dx.doi.org/10.35259/isi.sact.2019_32708.
Texto completoDing, Huihua, Fan-Lin Wu, Dan-Yun Lai, Yuan-Jia Tang, Zhao-Wei Xu, Ming-Liang Ma, Shu-Juan Guo et al. "165 Identification of serum biomarkers for systemic lupus erythematosus using a library of phage displayed random peptides and deep sequencing". En 13th International Congress on Systemic Lupus Erythematosus (LUPUS 2019), San Francisco, California, USA, April 5–8, 2019, Abstract Presentations. Lupus Foundation of America, 2019. http://dx.doi.org/10.1136/lupus-2019-lsm.165.
Texto completoPloos van Amstel, J. K., A. L. van der Zanden, E. Bakker, P. H. Reitsma y R. M. Bertina. "INDEPENDENT ISOLATION OF HUMAN PROTEIN S cDNA AND THE ASSIGNMENT OF THE GENE TO CHROMOSOME 3". En XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644638.
Texto completoAhmed, Kafil, Vyankatesh Pidiyar, Syed Ahmed y Sanket Shah. "Development of anti-SARS-CoV-2 specific scFv antibody library from convalescent plasma of COVID-19 recovered patients using phage display technology". En International Symposium on Immunobiological. Instituto de Tecnologia em Imunobiológicos, 2021. http://dx.doi.org/10.35259/isi.2021_46568.
Texto completoPearson, Hannah. "Making Collection Management Manageable: A Three-Phase Approach to an Annual Subscription Review". En Charleston Library Conference. Purdue Univeristy, 2020. http://dx.doi.org/10.5703/1288284317143.
Texto completoOrcutt, Darby. "The User‐Driven Collection 4.0: The Next Phase in User‐Driven Monographic Acquisition". En Charleston Library Conference. Purdue University Press, 2016. http://dx.doi.org/10.5703/1288284316286.
Texto completoHuber, P., J. Dalmon, M. Laurent, G. Courtois, D. Thevenon y G. Marguerie. "CHARACTERIZATION OFTHE 5’FLANKING REGION FOR THE HUMAN FIBRINOGEN β GENE". En XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642889.
Texto completoRathemacher, Andrée, Robert Heaton, Noah Levin y Christine Stohn. "Six Impossible Things: Moving KBART into the Next Decade". En Charleston Library Conference. Purdue Univeristy, 2020. http://dx.doi.org/10.5703/1288284317173.
Texto completoInformes sobre el tema "Phage library"
Pai, Jih T. Tumor Targeting with Phage Library. Fort Belvoir, VA: Defense Technical Information Center, julio de 2000. http://dx.doi.org/10.21236/ada383701.
Texto completoSiciliano, E. R. y E. D. Arthur. Medium-Energy Nuclear Data Library (MENDLIB): Phase 1. Office of Scientific and Technical Information (OSTI), octubre de 1987. http://dx.doi.org/10.2172/5978252.
Texto completoCiezki, John G. y Robert W. Ashton. PEBB Feedback Control Low Library. Volume 1: Three-Phase Inverter Control Algorithms. Fort Belvoir, VA: Defense Technical Information Center, enero de 1999. http://dx.doi.org/10.21236/ada360711.
Texto completoBaughman, Sue, Ava Brillat, Gordon Daines, Greg Davis, Stephanie JH McReynolds, Margaret Roller y Kevin Borden. Building a Community of Assessment: Final Report of the Research Library Impact Framework Pilot Initiative. Association of Research Libraries, marzo de 2023. http://dx.doi.org/10.29242/report.rlif2023.
Texto completoEyal, Yoram y Sheila McCormick. Molecular Mechanisms of Pollen-Pistil Interactions in Interspecific Crossing Barriers in the Tomato Family. United States Department of Agriculture, mayo de 2000. http://dx.doi.org/10.32747/2000.7573076.bard.
Texto completoPinelli, Thomas E., John M. Kennedy y Terry F. White. NASA/DoD Aerospace Knowledge Diffusion Research Project. Report Number 10. Summary Report to Phase 3 Academic Library Respondents Including Frequency Distributions. Fort Belvoir, VA: Defense Technical Information Center, agosto de 1991. http://dx.doi.org/10.21236/ada252069.
Texto completoEpel, Bernard L., Roger N. Beachy, A. Katz, G. Kotlinzky, M. Erlanger, A. Yahalom, M. Erlanger y J. Szecsi. Isolation and Characterization of Plasmodesmata Components by Association with Tobacco Mosaic Virus Movement Proteins Fused with the Green Fluorescent Protein from Aequorea victoria. United States Department of Agriculture, septiembre de 1999. http://dx.doi.org/10.32747/1999.7573996.bard.
Texto completo