Bibliografías temáticas / Phae display

Literatura académica sobre el tema "Phae display"

Autor: Grafiati
Publicado: 4 de junio de 2021
Última modificación: 2 de febrero de 2022

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Artículos de revistas sobre el tema "Phae display"

1

Wilson, Dan R. y B. Brett Finlay. "Phage display: applications, innovations, and issues in phage and host biology". Canadian Journal of Microbiology 44, n.º 4 (1 de abril de 1998): 313–29. http://dx.doi.org/10.1139/w98-015.

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In the 7 years since the first publications describing phage-displayed peptide libraries, phage display has been successfully employed in a variety of research. Innovations in vector design and methods to identify target clones account for much of this success. At the same time, not all ventures have been entirely successful and it appears that phage and host biology play important roles in this. A key issue concerns the role played by a displayed peptide or protein in its successful expression and incorporation into virions. While few studies have examined these issues specifically in context of phage display, the literature as a whole provides insight. Accordingly, we review phage biology, relevant aspects of host biology, and phage display applications with the goals of illustrating (i) relevant aspects of the interplay between phage-host biology and successful phage display and (ii) the limitations and considerable potential of this important technology.Key words: bacteriophage M13, phage display, pIII, pVIII, expression libraries.
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2

Popovych, O. M., I. M. Budzulyak, V. O. Kotsyubynsky, O. V. Popovych, B. I. Rachiy, R. V. Ilnytskyi y L. S. Yablon. "Methods of obtaining nickel molybdates and composites of molybdate/carbon material for electrodes of hybrid supercapacitors (Review)". Physics and Chemistry of Solid State 21, n.º 4 (30 de diciembre de 2020): 650–59. http://dx.doi.org/10.15330/pcss.21.4.650-659.

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Nickel molybdate due to its electronic configuration, stable crystalline framework, oxidation-reduction behavior displays perfect physical and chemical properties and rather high electrical conductivity that altogether lets the material display high total capacity. The research work classified modern methods of obtaining nickel molybdates and composites with carbon material on their basis. We have analyzed the fundamental stages of hydrothermal, microwave synthesis, ultrasonic dispersion, mechano-chemical, sol-gel method, and chemical precipitation method. The influence of different synthesis conditions on phase structure, morphology, physical and electrochemical properties of material was displayed.
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Cress, Jeffrey D., Lawrence J. Hettinger, James A. Cunningham, Gary E. Riccio, Grant R. McMillan y Michael W. Haas. "An Initial Evaluation of a Direct Vestibular Display in a Virtual Environment". Proceedings of the Human Factors and Ergonomics Society Annual Meeting 40, n.º 22 (octubre de 1996): 1131–35. http://dx.doi.org/10.1177/154193129604002205.

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The US Air Force Armstrong Laboratory's Human Interface Technology Branch is currently investigating the development and potential application of direct vestibular displays. The Electrical Vestibular Stimulus (EVS) technology described in this paper uses electrodes located behind the ears to deliver a low-level electrical current in the area of the eighth cranial nerve of the central nervous system to produce a compelling sensation of roll motion about the body's fore-aft axis. In this study, subjects experienced the EVS display while simultaneously observing a large field-of-view visual roll display, and were asked to rate various aspects of quality and magnitude of self-motion. The two displays were driven in a sinusoidal fashion at various phase relationships relative to one another. Results revealed that the fidelity of the motion experience depended upon the phase relationship between the two displays. Results also indicated that when an appropriate phase relationship was used, the vestibular display significantly improved the fidelity of the motion experience when compared to a visual-only display.
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4

P. W. M. Tsang, P. W. M. Tsang, Y. T. Chow Y.-T. Chow, T. C. Poon T.-C. Poon y and J. P. Liu and J.-P. Liu. "Generation and optical display of a binary-sampled phase-only hologram". Chinese Optics Letters 14, n.º 1 (2016): 010004–10007. http://dx.doi.org/10.3788/col201614.010004.

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Chikaev, A. N., A. P. Rudometov, Yu A. Merkulyeva y L. I. Karpenko. "Phage display as a tool for identifying HIV-1 broadly neutralizing antibodies". Vavilov Journal of Genetics and Breeding 25, n.º 5 (10 de septiembre de 2021): 562–72. http://dx.doi.org/10.18699/vj21.063.

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Combinatorial biology methods offer a good solution for targeting interactions of specific molecules by a high-throughput screening and are widely used for drug development, diagnostics, identification of novel monoclonal antibodies, search for linear peptide mimetics of discontinuous epitopes for the development of immunogens or vaccine components. Among all currently available techniques, phage display remains one of the most popular approaches. Despite being a fairly old method, phage display is still widely used for studying protein-protein, peptide-protein and DNA-protein interactions due to its relative simplicity and versatility. Phage display allows highly representative libraries of peptides, proteins or their fragments to be created. Each phage particle in a library displays peptides or proteins fused to its coat protein and simultaneously carries the DNA sequence encoding the displayed peptide/protein in its genome. The biopanning procedure allows isolation of specific clones for almost any target, and due to the physical link between the genotype and the phenotype of recombinant phage particles it is possible to determine the structure of selected molecules. Phage display technology continues to play an important role in HIV research. A major obstacle to the development of an effective HIV vaccine is an extensive genetic and antigenic variability of the virus. According to recent data, in order to provide protection against HIV infection, the so-called broadly neutralizing antibodies that are cross-reactive against multiple viral strains of HIV must be induced, which makes the identification of such antibodies a key area of HIV vaccinology. In this review, we discuss the use of phage display as a tool for identification of HIV-specific antibodies with broad neutralizing activity. We provide an outline of phage display technology, briefly describe the design of antibody phage libraries and the affinity selection procedure, and discuss the biology of HIV-1-specific broadly neutralizing antibodies. Finally, we summarize the studies aimed at identification of broadly neutralizing antibodies using various types of phage libraries.
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6

Smith, George P. y Valery A. Petrenko. "Phage Display". Chemical Reviews 97, n.º 2 (abril de 1997): 391–410. http://dx.doi.org/10.1021/cr960065d.

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Burton, Dennis R. "Phage display". Immunotechnology 1, n.º 2 (agosto de 1995): 87–94. http://dx.doi.org/10.1016/1380-2933(95)00013-5.

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Brichta, J., M. Hnilova y T. Viskovic. "generation of hapten-specific recombinant antibodies: antibody phage display technology: a review". Veterinární Medicína 50, No. 6 (28 de marzo de 2012): 231–52. http://dx.doi.org/10.17221/5620-vetmed.

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Production of antibodies has been revolutionized by the development of modern molecular biology methods for the expression of recombinant DNA. Phage display technology represents one of the most powerful tools for production and selection of recombinant antibodies and has been recognized as a valuable alternative way for the preparation of antibodies of a desired specificity. In comparison to poly- and monoclonal antibodies, recombinant antibodies using the phage display technology can be prepared faster, in more automatic process and with reduced consumption of laboratory animals. This review summarizes current trends of phage display technology with focus on the generation of hapten-specific recombinant antibodies and gives the examples of successful applications of phage display in the environmental analysis of low molecular weight compound.
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9

Feng Zhou, Feng Zhou, Qionghua Wang Qionghua Wang, Di Wu Di Wu y Jianpeng Cui Jianpeng Cui. "Polymer-stabilized blue phase liquid crystal display with slanted wall-shaped electrodes". Chinese Optics Letters 10, n.º 2 (2012): 022301–22303. http://dx.doi.org/10.3788/col201210.022301.

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Sui, Xiaomeng, Zehao He, Hao Zhang, Liangcai Cao, Daping Chu y Guofan Jin. "Spatiotemporal double-phase hologram for complex-amplitude holographic displays". Chinese Optics Letters 18, n.º 10 (2020): 100901. http://dx.doi.org/10.3788/col202018.100901.

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Tesis sobre el tema "Phae display"

1

De, Leon Ellen Jane Biotechnology &amp Biomolecular Sciences Faculty of Science UNSW. "Engineering antibodies against complex platelet antigens using phage display technology". Awarded by:University of New South Wales, 2007. http://handle.unsw.edu.au/1959.4/37009.

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Platelets are small anucleate cell fragments found in blood whose physiological role is important in maintaining haemostasis. In vivo, platelet surface glycoproteins mediate the mechanistic roles of platelets, and polymorphic changes to these glycoproteins have been observed to have significant effects on the platelet cellular function and such changes may include over-expression, under-expression and antigenicity of the protein. Human platelet antigens (HPA) are a result of polymorphic differences in platelet surface glycoproteins which have been found to be variably expressed in the population. Foetal maternal alloimmune thrombocytopaenia (FMAIT) is a condition that is observed in the unborn foetus and neonates due to HPA incompatibility between the mother and the foetus. HPA incompatibility accounts for a majority of severe thrombocytopaenic cases in neonates, and delayed diagnosis and treatment of such a condition often lead to intracranial haemorrhage. The risk in neonates diagnosed with FMAIT becomes increasingly significant in cases where intra-uterine (during pregnancy) platelet transfusion is the only effective therapeutic option. There are currently no antenatal screening programs for this condition, and laboratory diagnosis of FMAIT relies on the detection of maternal alloantibodies and parental HPA typing. For these reasons a significant amount of research is currently being invested into the isolation of recombinant antibodies with specific reactivity against FMAIT-related platelet antigens. Stable and specific recombinant platelet antibodies have great potential as a diagnostic agent in antenatal screening and broad-scale HPA typing of blood donors for platelet transfusion. Further characterisation of the isolated antibody may lead to a possible therapeutic agent. Studies by previous researchers have shown that the traditional methods (ie. Mouse monoclonal and EBV transformation) of obtaining monoclonal antibodies against FMAIT-related antigens have proven unsuccessful. The continuing progress in the discipline of phage display has produced several novel antibodies against self and non-self antigens. A further advantage in the application of phage display technology for the isolation of novel antibodies is the easy transition from bacterial to mammalian expression for the characterisation of glycosylated antibodies. The main focus of this project was to create and isolate a recombinant human anti-HPA-3a antibody using phage display for its possible application as a therapeutic or diagnostic agent.
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2

Nangola, Sawitree. "The interference of human immunodeficiency virus assembly and maturation by ankyrin repeat proteins". Thesis, Paris 11, 2011. http://www.theses.fr/2011PA112044.

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Le but de ce travail est de découvrir des nouvelles protéines suceptibles d'interférer avec le cycle vital du virus HIV. De par leur repliement, les protéines à motifs ankyrines peuvent constituer une ossature protéique trés bien adaptée à cet objectif. Plusieurs interacteurs spécifiques de la protéine MA-CA du HIV ont été sélectionnées par exposition sur phage à partir d'une bibliothèque de variants d'ankyrines. Trois protéines isolées ont été produites à partir de clones ayant une forte activité de liaison. Le meilleur interacteur protéique (1D4) interagit avec un épitope situié sur le domaine CA. La constante de dissociation entre 1D4 et la protéine HACA a été déterminée par Calorimétrie de Titrage Isotherme (ou ITC) et est égale à 0,45M. La protéine 1D4 n'a pas d'effet détectable sur la maturation virale suivie par une technique ELISA de dosage de la Protease du HIV. En revanche, cette protéine interfere avec l'assemblage viral dans des cellules supT1 qui exprime de façon stable la protéine 1D4 sous forme myristoylée. Ce resultat ouvre une perspective d'appoche pour interferer avec le cycle vital du HIV
Presently, the standard regimen for antiretroviral treatment is highly active antiretroviral therapy (HAART). However, this strategy inherits the well-known side effects and is prone to promote the HIV drug-resistant strains. As a consequence, gene therapy has been introduced as an alternative approach. In this study, we aimed to discover the novel protein-based agents for intervening viral replication by gene targeting procedure. Regarding the efficient folding dynamic in cytoplasm, ankyrin repeat protein was considered to be a candidate scaffold. Several engineered ankyrin binders specific to HIV MA-CA domain were successfully retrieved from the ankyrin-displayed phage library. Three positive clones with high binding activity by ELISA were selected for further analyzing their binding property in soluble form. The best binder, 1D4, recognized its epitope located on CA domain as shown by Western immunobloting and ELISA. The affinity of 1D4 against H6MA-CA was 0.45 μM with one to two moles of target molecule determined by isothermal titration calorimetry (ITC). Although 1D4 exhibited no effect on viral maturation as verified by an ELISA based HIV protease assay technique, it disturbed the viral assembly process in Sup-T1 cells which stably expressed the myristoylated 1D4. This finding has provided a concrete prospect for HIV life cycle interruption by stem cell gene therapy in the future
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3

Rosander, Anna. "Novel applications of shotgun phage display /". Uppsala : Dept. of Microbiology, Swedish Univ. of Agricultural Sciences, 2004. http://epsilon.slu.se/a450.pdf.

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Holmes, David Ian Roderick. "Phage display of chymotrypsin inhibitor II". Thesis, Imperial College London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283414.

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Smith, Mathew Wayne. "Phage display and experimental brain therapeutics". Thesis, Cardiff University, 2009. http://orca.cf.ac.uk/55853/.

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Phage display, a powerful polypeptide display technology, affords the rapid identification of peptides and proteins that interact with a target of interest The aims of the project were the phage display identification of peptides that interact with a druggable target in a brain disorder (glioblastoma multiforme) and the identification of peptides that serve as targeting vectors for brain delivery. Validation studies were undertaken to qualify the use of a cyclic 7-mer peptide phage library against targets including streptavidin and paracetamol chosen as examples of a large complex and small simple molecule, respectively. With the aim of identifying peptide phages that bind to the luminal surface of brain micro vasculature, a primary in-vitro porcine model of the blood-brain barrier (BBB) comprising primary brain capillary endothelial cells was established and characterised. An in-vivo phage display was undertaken in the rat with the aim of identifying peptide sequences that mediated translocation across the BBB into brain grey matter. A 7-mer cyclic peptide was identified with sequence AC-SYTSSTM-CGGGS that enhanced the uptake of phages into brain grey matter by 4-fold compared to control wild-type phages. This peptide may serve as a novel targeting vector for the delivery of a therapeutic cargo to the brain. Caveolin-1 was identified as a potential new therapeutic target in in-vitro models of grade IV astrocytomas (glioblastoma multiforme), with siRNA knockdown of caveolin-1 associated with reduced glioma cell proliferation and invasiveness. With the caveolin-1 scaffolding domain (aa 81-101 in the caveolin-1 protein) as a target, an in-vitro peptide phage selection was undertaken and identified a series of peptides that bind the scaffolding domain with high affinity. These peptides will serve as a template for the development of low molecular weight peptidomimetics that inhibit caveolin-1 function. In conclusion, the studies in this thesis have demonstrated the utility of phage display in experimental therapeutics of brain disorders.
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Drever, Matthew. "Generating microcystin antibodies by phage display". Thesis, University of Aberdeen, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.445137.

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A naïve human antibody fragment phage display library was screened against conjugated microcystin-LR (MCLR).  Phage antibodies were eluted with free MCLR to promote the isolation of free antigen binders.  Isolated antibody fragments were cloned into a soluble expression vector and single-chain antibody (scAb) expressed in a bacterial host.  All scAbs bound free antigen in an indirect competition ELISA and levels of sensitivity were determined.  The most responsive clone 3A8 had an 800-fold increase in sensitivity to MCLR than previously documented scAbs and was able to detect levels below guidelines for MCLR in drinking water set by the World Health Organisation (WHO) at 1 μg/L.  Despite its sensitivity to MCLR, full characterisation revealed low levels of cross-reactivity with other microcystin variants. In vitro affinity maturation was employed to increase cross-reactivity to other microcystin variants in scab 3A8.  A chain-shuffled library was constructed where a naïve VL repertoire was shuffled with clone 3A8 VH chain.  The library was screened and isolated phage antibodies cloned and expressed as scAbs.  Chain-shuffled clone CSB-D9 displayed a 50-fold increase in cross-reactivity for a single microcystin variant and was capable of detecting all variants available below the guideline levels of 1 μg/L. The highly cross-reactive scab was used for the determination of total microcystin content in cyanobacterial extracts and results showed good correlation with HPLC quantification.  Immunoaffinity chromatography utilising scab CSB-D9 was used for the concentration of trace amount of microcystin from large volumes of water, out-performing columns generated with anti-microcystin whole antibody molecules. The ability of scab CSB-D9 to protect cultured hepatocytes against microcystin-induced apoptosis was also determined.  Results indicated a possible therapeutic application for human antibody fragments isolated from phage display libraries.
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7

Meyer, Scott C. "Non-Covalent Selection Methodologies Utilizing Phage Display". Diss., The University of Arizona, 2007. http://hdl.handle.net/10150/194059.

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In nature, non-covalent interactions are as important and dynamic as they are elusive. As such, the study of non-covalent interactions both in vivo and in vitro has proven to be challenging. Given the potential benefits of elucidating protein-protein, ligand-receptor, and other biologically relevant interactions, the development of methodologies for the study of non-covalent interactions is an attractive goal.Biologically encoded protein and peptide libraries that connect the genotypic information with the expressed phenotype have emerged in recent years as powerful methods for studying non-covalent interactions. One of the quintessential platforms for the creation of such libraries is phage display. In phage display, the connection between genetic information and the corresponding protein allows for the iterative isolation and amplification of library members that possess a desired function. Hence, an in vitro selection can be used to isolate epitopes that bind to desired targets or display specific attributes.We have sought to develop novel phage display methodologies that have the potential to expand the scope of this in vitro selection platform. Specifically, we developed a method for the non-covalent attachment of a small molecule ligand to a cyclic peptide library. This system localizes the phage display library to the ligand binding site, thus allowing for the translation of the selected cyclic peptides to a covalently tethered bivalent inhibitor.The first class of biological molecules that we chose to target with our methodology is the biologically and therapeutically important class of enzymes called protein kinases. In the first demonstration of this strategy, we were able to isolate cyclic peptide ligands for the model kinase PKA (cAMP-dependent protein kinase), which were subsequently translated to a bivalent inhibitor. This inhibitor showed both increased affinity and selectivity for PKA in relation to other protein kinases.In a separate project, we sought to develop a method for the isolation of small molecule-responsive mutants of a well-characterized protein scaffold from a phage display library. During these investigations, we discovered interesting homologous single-point mutations of the protein that resulted in large spherical oligomers that may mimic species relevant to the study of protein misfolding diseases such as Alzheimer's.
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Bonnert, Timothy Peter. "Strategies for making antibodies by phage display". Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294402.

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Ching, Ana Tung Ching. "Identificação de adesinas bacterianas por phage display". Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/87/87131/tde-05022013-084410/.

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A leptospirose é uma zoonose de importância mundial causada por bactérias do gênero Leptospira. No Brasil, a maioria dos casos é causada por L. interrogans sorovar Copenhageni. O objetivo destre trabalho foi identificar adesinas de leptospira pela técnica de Phage display. Bibliotecas com fragmentos genômicos resultaram na idendificação de ligantes de leptospira com afinidade por tecidos de hamster. Uma varredura dessas bibliotecas contra heparan sulfato proteoglicano (HSPG) identificou como ligantes as proteínas LigA e LigB. Proteínas recombinantes foram produzidas e submetidas à ligação às células de mamíferos e aos componentes de matriz extracelular. LigB recombinante foi capaz de se ligar ao HSPG, à heparina e às células de mamíferos. HSPG e heparina foram capazes de reduzir significativamente a interação dessa proteína com as células. Estes resultados evidenciam o papel de proteínas da leptospira na sua interação com o hospedeiro e ilustram a possibilidade do uso da técnica de phage display para identificar possíveis adesinas.
Leptospirosis is a worldwide important zoonosis caused by bacteria of the genus Leptospira. In Brazil, most cases is caused by L. interrogans serovar Copenhageni. Our goal was to identify leptospiras adhesins by phage display technique. Libraries of genomic fragments resulted in the identification of ligands with affinity for leptospiras hamster tissues. Screening these libraries against heparan sulfate proteoglycan (HSPG) identified the proteins LigA and LigB. Recombinant proteins were produced and subjected to binding to mammalian cells and extracellular matrix components. LigB recombinant was able to bind to HSPG, heparin and mammalian cells. HSPG and heparin were able to significantly reduce the interaction of this protein with cells. These results highlight the role of leptospiras proteins in its interaction with the host and illustrate the possibility of the use of phage display technique to identify potential adhesins.
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Gomes, Margarida. "Développement de bibliothèques de protéines artificielles permettant la création d’outils de reconnaissance moléculaire innovants". Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLS030.

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Le travail de thèse présente une approche innovante pour la construction d’une bibliothèque de protéines basées sur l’ossature protéique. L’objectif est de générer une source de biodiversité artificielle permettant la création de nouvelles capacités d’interaction avec des cibles d’intérêts. Une banque, basée sur une ossature protéique bactérienne avait déjà été construite dans l’équipe, mais elle nécessitait d’être optimisée. L’étape initiale a été d’explorer les raisons de l’instabilité des protéines de la banque de première génération, ceci par des approches d’étude de la structure in silico suivie d’une stratégie de mutagenèse dirigée. Des positions déstabilisantes existant dans la première banque ont donc été remplacées dans la banque de deuxième génération. La deuxième étape a eu pour objectif de diminuer le nombre de positions diversifiées et de simplifier le schéma de diversification des variants de la banque. Puis un procédé de filtration et de shuffling de ces variants a été mis au point pour augmenter la proportion de séquences codantes correctes. Une nouvelle stratégie de filtration basée sur la technique d’exposition sur phage a été élaborée, en exploitant le fait que la protéine matrice de la banque, l'ossature protéique a un partenaire biologique capable d’interagir sur la zone « constante », non modifiée par le schéma de diversification. Ainsi les variants de la banque exposés dans une conformation correcte à la surface des phages ont pu être capturés par ce partenaire. Ensuite, les séquences correspondant à ces variants ont été recombinées entre elles pour recréer une plus grande diversité utile. Une bibliothèque optimisée composée de 2.8 x 108 protéines indépendantes a ainsi été obtenue. Cette nouvelle banque optimisée a permis de sélectionner par Phage display, des interacteurs contre plusieurs cibles de structures différentes. Ces nouveaux interrupteurs sont spécifiques de leurs cibles et présentent des affinités de l’ordre du μM. Une approche de séquençage à haut débit a également été entreprise pour réaliser une analyse plus approfondie des séquences de cette bibliothèque et de notre processus de sélection. Cette approche nous a apporté une nouvelle dimension pour la caractérisation des banques construites au laboratoire notamment concernant la diversité réelle de ces banques. Pour le suivi de sélections, nous avons appréhendé le séquençage haut débit comme un moyen d’identifier les interacteurs spécifiques d’une cible par l’analyse exhaustive des séquences issues des sélections. L’objectif est ici de mettre au point un protocole utilisant l’approche NGS pour identifier les interacteurs spécifiques isolées par Phage Display
Here new methods to build a library of artificial proteins based on a new protein framework have been developed. The objective is to generate a source of artificial biodiversity allowing the creation of new interaction capacities with various specific targets. A first-generation library was previously built with this scaffold, but it needed to be optimized. The first step was to explore the reasons of the instability of the first generation proteins library through an in silico approaches followed by a site-directed mutagenesis strategy. The second step was to reduce the number of diversified positions and simplify the randomization scheme of the variants of the library. Then a method of filtering and shuffling of the variants of the bank was elaborated. To increase the proportion of correct coding sequences, a new filtration strategy based on the phage display technique has been developed, exploiting the fact that the scaffold of the librarie. This scaffold has a particularly interesting biological partner able to interact on the "constant" zone. This filtration made it possible to recover a set of well-folded clones. Then, DNA sequences corresponding to these clones were recombined with each other to recreate a greater useful diversity. An optimized library of 2.8 x 108 independent proteins was obtained. This new optimized library has enabled us to select, by a phage display approach, binders against several targets of different structures. These new binders are specific for their targets and have affinities in the μM range. A high throughput sequencing (NGS) approach was also undertaken to further analyse the library sequences and the selection process. This approach offers a new dimension for the characterization of the library built in the laboratory, especially concerning it actual diversity. To follow the selections, we have considered the NGS as a way to identify the target-specific binders through exhaustive analysis of the sequences obtained from selections. The objective here is to develop a general protocol using the NGS approach to identify specific binders isolated by Phage Display
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Libros sobre el tema "Phae display"

1

Hust, Michael y Theam Soon Lim, eds. Phage Display. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7447-4.

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Aitken, Robert, ed. Antibody Phage Display. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-302-2.

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O'Brien, Philippa M. y Robert Aitken. Antibody Phage Display. New Jersey: Humana Press, 2001. http://dx.doi.org/10.1385/1592592406.

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Antibody phage display: Methods and protocols. 2a ed. Dordrecht: Humana Press, 2009.

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Rosander, Anna. Novel applications of shotgun phage display. Uppsala: Swedish University of Agricultural Sciences, 2004.

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Carnazza, Santina. Phage display as a tool for synthetic biology. Hauppauge, N.Y: Nova Science Publishers, 2010.

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1950-, Guglielmino Salvatore, ed. Phage display as a tool for synthetic biology. Hauppauge, N.Y: Nova Science Publishers, 2010.

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(Editor), Carlos F. Barbas, ed. Phage Display. Cold Spring Harbor Laboratory Press, 2001.

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Antibody Phage Display. Humana Press, 2002.

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Tim, Clackson y Lowman Henry B, eds. Phage display: A practical approach. Oxford: Oxford University Press, 2004.

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Capítulos de libros sobre el tema "Phae display"

1

Shukla, Girja S. "Phage Display". En Encyclopedia of Cancer, 2836–39. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_4489.

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Collins, John. "Phage display". En Annual Reports in Combinatorial Chemistry and Molecular Diversity, 210–62. Dordrecht: Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-0-306-46904-6_15.

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Petropoulos, Konstantin. "Phage Display". En Methods in Molecular Biology, 33–51. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-931-0_3.

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Debnath, Mousumi, Godavarthi B. K. S. Prasad y Prakash S. Bisen. "Phage Display". En Molecular Diagnostics: Promises and Possibilities, 181–92. Dordrecht: Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-3261-4_12.

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Shukla, Girja S. "Phage Display". En Encyclopedia of Cancer, 1–5. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27841-9_4489-3.

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Shukla, Girja S. "Phage Display". En Encyclopedia of Cancer, 3506–11. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-46875-3_4489.

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Ehrlich, George K., Wolfgang Berthold y Pascal Bailon. "Phage Display Technology". En Methods in Molecular Biology, 195–208. Totowa, NJ: Humana Press, 2000. http://dx.doi.org/10.1007/978-1-60327-261-2_18.

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Ehrlich, George K., Pascal Bailon y Wolfgang Berthold. "Phage Display Technology". En Methods in Molecular Biology, 209–20. Totowa, NJ: Humana Press, 2000. http://dx.doi.org/10.1007/978-1-60327-261-2_19.

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Shim, Hyunbo. "Antibody Phage Display". En Recombinant Antibodies for Infectious Diseases, 21–34. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-72077-7_2.

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Zantow, Jonas, Gustavo Marçal Schmidt Garcia Moreira, Stefan Dübel y Michael Hust. "ORFeome Phage Display". En Methods in Molecular Biology, 477–95. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7447-4_27.

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Actas de conferencias sobre el tema "Phae display"

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Pao, Y. C. y Winston Yur. "An Interactive, Menu-Driven, Software for Flexural Analysis of Transversely Loaded Beams". En ASME 1992 International Computers in Engineering Conference and Exposition. American Society of Mechanical Engineers, 1992. http://dx.doi.org/10.1115/cie1992-0119.

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Abstract A set of computer programs written in QuickBASIC language has been developed as an instructional aid for the Mechanics of Materials course. It consists of 9 programs and over 50 supporting subprograms. Starting with the span and loading inputs, this software computes the support reactions and displays the diagrams of distributed loads, shearing force, bending moments, slope, and deflection distributions. Disk files are created to save the input and computed data and also the resulting displays for quick retrieval during any phase of the flexural analysis. Various shapes of cursors are created on screen for the user to select any menu involved in the analysis and/or a desired section of the beam for computation of the principal and maximum shearing stresses, for which Mohr’s circle display is also an optional feature. All operations are interactive and menu-driven, and provided with many helpful prompting messages to assist the user to specify the next request.
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Zellmann, Stefan, Martin Aumüller y Ulrich Lang. "Image-Based Remote Real-Time Volume Rendering: Decoupling Rendering From View Point Updates". En ASME 2012 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/detc2012-70811.

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Remote rendering is employed when the visualization task is too challenging for the hardware used to display a dataset or when it is too time consuming to transfer the complete dataset. Volume visualization with its dataset sizes growing with the 3rd power of their spatial resolution is such a task. Since remote rendering introduces additional sources of latency, its applicability to virtual environments is limited because of the required low delays from user action to displayed image. We counter these latencies with image-based rendering techniques: color image data along with additional depth information is warped, while new data has not been completely received. Using these approximate images, it is possible to decouple the cheap display phase from rendering. While depth values are trivially deduced for polygons, we contribute heuristics for volumetric datasets with varying transparency.
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Potvin-Bernal, J. y L. H. Shu. "Promoting Energy-Efficient Driving Using Associative Graphical Displays: Can a Cup of Coffee Encourage You to Drive More Smoothly?" En ASME 2019 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/detc2019-97296.

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Abstract Substantial energy savings during the use phase of internal-combustion and electric automobiles can be achieved by increasing eco-driving behavior, particularly reduced acceleration and braking. However, motivating widespread adoption of this behavior is challenging, with obstacles including incompatibility with drivers’ values and priorities, and disassociation between drivers’ actions and observable consequences. Efforts focused on informational approaches, e.g., training programs and educational campaigns, are both difficult to scale up and largely ineffective, with drivers reluctant to make long-term changes. Alternatively, behavior can be influenced by redesigning the context within which the behavior occurs. Such an intervention must be effective across demographics and underlying behaviors to achieve ubiquity. The current study investigates the perceived effect on driving style of a simple graphical dashboard display depicting an animated coffee cup. This display incorporates associative mental models and contextual relevance to increase the salience of inefficient vehicle movements and nudge drivers to adopt a smoother driving style. An online Amazon-Mechanical-Turk survey with 92 participants revealed a significant preference for the coffee cup over two other displays when controlling for demographic variables. This result offers preliminary evidence suggesting that greater success at promoting eco-driving may be achieved by using a behavioral nudge.
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Piao, Mei-Lan, Jae-Hyeung Park, Nam Kim y Hyun-Soo Kang. "Phase optimization for phase contrast projection display". En SPIE OPTO: Integrated Optoelectronic Devices, editado por Liang-Chy Chien y Ming Hsien Wu. SPIE, 2009. http://dx.doi.org/10.1117/12.808808.

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Nomura, Takanori. "Phase imaging in-line digital holography with random phase modulation". En Three-Dimensional Imaging, Visualization, and Display 2019, editado por Jung-Young Son, Bahram Javidi y Osamu Matoba. SPIE, 2019. http://dx.doi.org/10.1117/12.2521044.

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Wu, Jiachen, Kexuan Liu y Liangcai Cao. "Calculating real-time phase-only holograms through autoencoder neural network". En Advances in Display Technologies XI, editado por Jiun-Haw Lee, Qiong-Hua Wang y Tae-Hoon Yoon. SPIE, 2021. http://dx.doi.org/10.1117/12.2579244.

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Moreno, Ignacio S., Andres Marquez, Josep Nicolas, Juan Campos y Maria J. Yzuel. "Diffraction efficiency of phase-only diffractive elements displayed onto twisted nematic liquid crystal displays". En Photonics Europe, editado por Frank Wyrowski. SPIE, 2004. http://dx.doi.org/10.1117/12.533293.

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Unterseher, Fred D. y Rebecca E. Deem. "Reduced-image full-aperture achromatic phase amplitude hologram". En Sixth International Symposium on Display Holography, editado por Tung H. Jeong. SPIE, 1998. http://dx.doi.org/10.1117/12.301493.

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Cao, Liangcai, Zehao He, Tingting Zhou y Chao Han. "Performance analysis for holographic display based on phase only spatial light modulator". En Advances in Display Technologies IX, editado por Qiong-Hua Wang, Tae-Hoon Yoon y Jiun-Haw Lee. SPIE, 2019. http://dx.doi.org/10.1117/12.2511150.

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Ortiz-Gutiérrez, Mauricio, Mario Pérez Cortés, Juan Carlos Ibarra-Torres, Arturo Olivares-Pérez y Yenisey del Rocío Ponce de León Villanueva. "3D surface reconstruction using Talbot effect and Fourier transform of phase objects". En Advances in Display Technologies X, editado por Jiun-Haw Lee, Qiong-Hua Wang y Tae-Hoon Yoon. SPIE, 2020. http://dx.doi.org/10.1117/12.2547169.

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Informes sobre el tema "Phae display"

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Wiker, Steven F. Teletouch Display Development. Phase 1. Fort Belvoir, VA: Defense Technical Information Center, julio de 1988. http://dx.doi.org/10.21236/ada206919.

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Davis, Lawrence, Betsy Constantine, Stuart Shieber, Joe Marks y Rebecca Hwa. Optimizing Cockpit Display Configurations with a Genetic Algorithm System. Phase 1. Fort Belvoir, VA: Defense Technical Information Center, diciembre de 1994. http://dx.doi.org/10.21236/ada289799.

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Perucho, Manuel. A New Approach for the Immunodiagnostics of Breast Cancer by Random Peptide Phage Display. Fort Belvoir, VA: Defense Technical Information Center, julio de 1999. http://dx.doi.org/10.21236/ada384062.

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Sears, Pamela y Chi-Huey Wong. Exploiting Molecular Diversity of Enzymes Based on Phage Display: Development of Novel Enzymatic Catalysts. Fort Belvoir, VA: Defense Technical Information Center, abril de 1999. http://dx.doi.org/10.21236/ada362539.

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Perucho, Manuel. A New Approach for the Immunodiagnostics of Breast Cancer by Random Peptide Phage Display. Fort Belvoir, VA: Defense Technical Information Center, julio de 2000. http://dx.doi.org/10.21236/ada393162.

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Rash, Clarence E., Thomas H. Harding, John S. Martin y Howard H. Beasley. Concept Phase Evaluation of the Microvision, Inc. Aircrew Integrated Helmet System HGU-56P Virtual Retinal Display,. Fort Belvoir, VA: Defense Technical Information Center, agosto de 1999. http://dx.doi.org/10.21236/ada367318.

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Scharine, Angelique A. y Rachel A. Weatherless. Helmet Electronics & Display System-Upgradeable Protection (HEaDS-UP) Phase III Assessment: Headgear Effects on Auditory Perception. Fort Belvoir, VA: Defense Technical Information Center, noviembre de 2013. http://dx.doi.org/10.21236/ada592067.

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Harding, Thomas H., John S. Martin, Howard H. Beasley y Clarence E. Rash. Final Phase One Evaluation of the Microvision, Inc. Aircrew Integrated Helmet System (AIHS) HGU-56P Scanning Laser Display. Fort Belvoir, VA: Defense Technical Information Center, junio de 2001. http://dx.doi.org/10.21236/ada395153.

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Meighan, Mark A. y Susan Deutscher. Phage Fab Display Selection In Vitro and In Vivo: Novel Means to Identify New Breast Cancer Avid Compounds. Fort Belvoir, VA: Defense Technical Information Center, abril de 2001. http://dx.doi.org/10.21236/ada395332.

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Meighan, Mark A. Phage Fab Display Selection In Vitro and In Vivo: Novel Means to Identify New Breast Cancer Avid Compounds. Fort Belvoir, VA: Defense Technical Information Center, abril de 2003. http://dx.doi.org/10.21236/ada415809.

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