Tesis sobre el tema "Peig"
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Weiss, Sabine. "Uronsäure-funktionalisierte PEI- bzw. PEI-PEG-Konjugate und artifizielle Chromosomen für den nicht-viralen Gentransfer". Diss., lmu, 2006. http://nbn-resolving.de/urn:nbn:de:bvb:19-62521.
Texto completoFarvadi, F., A. M. Tamaddon y F. Hashemi. "PEG-grafted Hyperbranched Polyethyleneimine-Oxidized Single Walled Carbon Nanotube Complex (PEG-PEI-SWNT) for Sustained Delivery of Doxorubicin". Thesis, Sumy State University, 2012. http://essuir.sumdu.edu.ua/handle/123456789/34928.
Texto completoLelièvre, Yves. "Elaboration de vecteurs d'ADN, substrats de gélatinases". Paris 6, 2005. http://www.theses.fr/2005PA066150.
Texto completoNurme, Tobias. "The PEIS Slippers". Thesis, Örebro University, School of Science and Technology, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-10320.
Texto completoAt the AASS laboratory located in “Teknikhuset” at ORU there are research projects that has the goal to create an intelligent home. This home should be used in care of elders and other people that are in need of care. It has already a lot of technology embedded in the different parts of the apartment, i.e. a robot arm in the fridge.
To know when these modules should be activated for use or not, the location of the user can be used. An example would be that the fridge door shouldn't open when the user accidentally tells it to when he or she is in the bathroom, but it should when he or she stands in front of the fridge. Then how to know where the person are located?
This is what the idea of this thesis is, to create a location tool to be used in the care of elders. It will be embedded in the intelligent environment in the apartment and in later projects together with other systems monitor the patient.
What hardware to use and how to connect them together are a major task in this thesis. And also writing the application to be able to embed the tool in the environment system. How did the result turn out, and what can future development can be done.
Vid AASS laboratoriet som är beläget i Teknikhuset vid Örebro Universitet finns det forskningsprojekt med mål att skapa ett intelligent hem. Detta hem ska användas inom omsorgen för gamla och andra personer som är i behov av vård. Det har redan idag mycket teknologi inbyggt i diverse saker, exempelvis en robotarm i kylen.
För att veta när dessa moduler ska arbeta eller inte så är positionen på användaren viktig. Det vore inte så bra om kylskåpsdörren öppnades av ett misstag när användaren befinner sig på toaletten. Men dörren ska öppna sig när användaren står framför kylen. Men hur vet man då vart användaren är?
Idéen med detta examensarbete är att skapa en sådan lösning som kan hålla kolla på positionen av en person. Lösningen ska sedan vara en del av det intelligenta system som i framtida projekt skall användas för att övervaka personen.
Vilken hårdvara och hur den skall kopplas samman är en stor del av detta arbete, och även hur applikationen som skall integrera hårdvarulösningen i det intelligenta systemet utvecklades. Hur ser resultatet ut och vad finns det för möjligheter att vidareutveckla detta resultat i framtiden.
Endres, Thomas [Verfasser] y Thomas [Akademischer Betreuer] Kissel. "Biodegradable amphiphilic PEG-PCL-PEI triblock copolymers designed for the self-assembly of multifunctional gene carriers / Thomas Endres. Betreuer: Thomas Kissel". Marburg : Philipps-Universität Marburg, 2013. http://d-nb.info/103231396X/34.
Texto completoPeng, Ying. "Synthesis, structures and reactions of aluminum(I) and aluminum(III) compounds". Doctoral thesis, [S.l. : s.n.], 2004. http://webdoc.sub.gwdg.de/diss/2004/peng/peng.pdf.
Texto completoStoffle, Richard W. "Solar PEIS Orientation Talks". University of Arizona Libraries, Special Collections, 2013. http://hdl.handle.net/10150/301462.
Texto completoCortella, Giacomo. "Development of a polyplexes-based miRNA delivery system in a 3D-bioplotted osteoarthritis cellular model". Master's thesis, Alma Mater Studiorum - Università di Bologna, 2022. http://amslaurea.unibo.it/25380/.
Texto completoWoodley, Thomas W. "Designing and fabricating PEIT systems". Thesis, Queensland University of Technology, 2016. https://eprints.qut.edu.au/101960/4/Thomas_Woodley_Thesis.pdf.
Texto completoEricsson, Peter. "Including Android Devices in PEIS-ecologies". Thesis, Örebro universitet, Akademin för naturvetenskap och teknik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-20407.
Texto completoPeng, Yang [Verfasser]. "Signatures of topological superconductivity / Yang Peng". Berlin : Freie Universität Berlin, 2017. http://d-nb.info/1137867906/34.
Texto completoLee, Pei-Yu. "Child abuse and neglect reporting among nurses in Taiwan : professional knowledge, perceptions, attitudes, and self-efficacy". Thesis, Queensland University of Technology, 2008. https://eprints.qut.edu.au/17800/1/Pei-Yu_Lee_Thesis.pdf.
Texto completoChiang, Pei-Shan. "Home literacy education of Taiwanese Australian families : a sociological analysis". Thesis, Queensland University of Technology, 2010. https://eprints.qut.edu.au/43678/1/Pei-Shan_Chiang_Thesis.pdf.
Texto completoCher, Pei Hua. "Running efficiency measures and their relationship with speed". Thesis, Queensland University of Technology, 2016. https://eprints.qut.edu.au/97686/1/Pei%20Hua_Cher_Thesis.pdf.
Texto completoLin, Pei-Ta. "Strategic uncertainty in capital markets". Thesis, Queensland University of Technology, 2017. https://eprints.qut.edu.au/104122/1/Pei-Ta_Lin_Thesis.pdf.
Texto completoI'Ons, Trevor Andrew. "Improving the PEG ratio". Diss., University of Pretoria, 2010. http://hdl.handle.net/2263/24000.
Texto completoDissertation (MBA)--University of Pretoria, 2010.
Gordon Institute of Business Science (GIBS)
unrestricted
林潔賢 y Kit-yin Canace Lam. "Battling for the environment on Peng Chau". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B31972470.
Texto completoMarinho, Patrícia Isabel de Oliveira. "Impacto do processamento de sobrevivência no PEIR". Master's thesis, Universidade de Aveiro, 2012. http://hdl.handle.net/10773/10232.
Texto completoEsta investigação incide sobre a aplicação de dois paradigmas associados a dois processos de memória distintos: a retenção e o esquecimento. Ao nível da retenção, recentemente a memória humana começou a ser analisada com base na perspetiva evolutiva, sendo sugerido que o modo como a memória funciona reflete as pressões seletivas que os humanos deverão ter enfrentado ao longo da sua evolução. Nesta linha, tem sido demonstrado que os humanos parecem estar “sintonizados” para reter melhor informação quando esta é processada em contextos de sobrevivência, comparativamente com várias condições de controlo (efeito de sobrevivência). Quanto ao esquecimento, o Paradigma de Esquecimento Induzido pela Recuperação (PEIR) tem demonstrado que detemos um mecanismo capaz de inibir informação, para que possamos recuperar outra informação desejada. Este paradigma é tipicamente composto por 4 fases: fase de estudo, fase de evocação parcial, período de retenção/distração, e fase de evocação total (usualmente a tarefa de evocação guiada pela categoria). Durante a fase de evocação parcial é recuperada parte da informação apresentada na fase de estudo, ocorrendo um mecanismo inibitório da informação não solicitada, para que a evocação do material alvo seja mais bem sucedida. Este mecanismo resulta numa pior recuperação posterior da informação não recuperada comparativamente com material nunca submetido à recuperação seletiva (esquecimento induzido pela recuperação - RIF). Por outro lado, é observado um efeito de facilitação para o material recuperado nesta fase. O objetivo da junção destes dois paradigmas era averiguar se efeito de sobrevivência ocorria no PEIR, assim como avaliar a suscetibilidade do processamento de sobrevivência aos efeitos tipicamente observados no PEIR. Deste modo, a experiência 2 conjuga estes dois paradigmas. Tipicamente, o PEIR é usado com categorias semânticas; contudo, por várias razões, no presente estudo foram usadas categorias ad hoc. Dada a inexistência de normas Portuguesas para este material foi realizado um estudo piloto que permitiu obter as frequências e tipicidade de exemplares para várias categorias ad hoc. Na primeira experiência procedemos à aplicação do PEIR com estas categorias ad hoc para avaliarmos a ocorrência do efeito de facilitação e do RIF com o material selecionado. Esta experiência replicou o efeito de facilitação, mas não o RIF. Na segunda experiência, procedemos à junção do paradigma de sobrevivência ao PEIR. Os resultados desta experiência não replicaram o efeito de sobrevivência, ou seja, não foi obtido um maior nível de retenção na condição de sobrevivência comparativamente ao grupo de controlo. O efeito de facilitação foi replicado nesta experiência; dada a não obtenção do RIF na primeira experiência, não podemos tirar elações sobre a suscetibilidade do processamento de sobrevivência ao mecanismo de inibição presente no PEIR. São discutidos os vários fatores que poderão estar subjacentes a estes resultados. Foram ainda deixadas em aberto várias questões que, deverão ser avaliadas em estudos experimentais futuros.
This research focuses on the application of two memory paradigms: retention and forgetting. Recently, human memory began to be conceptualized from an evolutionary perspective. Some authors have suggested that the way memory works likely reflects the selection pressures humans faced throughout evolution. Following this reasoning it has been shown that memory performance is better when information is encoded in survival contexts as compared to various control conditions (survival effect). The retrieval-practice paradigm has demonstrated that memory uses an inhibitory mechanism that allows one to more successfully retrieve a given information when competing information is present. This paradigm typically includes four phases: study, retrieval practice, retention period, and testing (usually a category-cued recall task). During the retrieval practice, part of the initially studied information is retrieved; throughout this process, the non-target information is inhibited contributing to the retrieval success of the required information. As a result, later on, memory performance for the inhibited material is lower than for material that was never practiced (retrieval-induced forgetting - RIF). On the other hand, the retrieved material is the best recalled in the final task (facilitation effect). We aim to combine these two approaches in order to investigate the occurrence of the survival effect in the retrieval-practice paradigm, as well as to investigate the susceptibility of survival processing to the effects typically observed in this forgetting paradigm. Typically, the retrieval-practice paradigm uses semantic categories; however, for various reasons, we used ad hoc categories. In an initial pilot study, Portuguese norms (frequency and typicality of generation) for ad hoc categories were collected. The first experiment tested whether the typical RIF and facilitation effects would be obtained using this material. The facilitation effect was obtained, but not the RIF. In the second experiment, the retrieval-practice paradigm and survival procedure were combined. The typical survival effect was not obtained, that is, survival processing did not increase recall as compared to the control condition. The facilitation effect was replicated in this experiment; given that the RIF was not obtained in experiment 1, no conclusions can be made about the susceptibility of survival processing to inhibitory effects. We discuss several factors that might underlie the current results. We also propose a set of to-be conducted experiments that would help clarify the obtained results.
Lam, Kit-yin Canace. "Battling for the environment on Peng Chau". Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25205808.
Texto completoOrtiz, Almirall Xavier. "Eliminació de contaminants orgànics persistents d’oli de peix". Doctoral thesis, Universitat Ramon Llull, 2011. http://hdl.handle.net/10803/31962.
Texto completoEn la presente tesis doctoral se han estudiado diversos métodos para la eliminación de contaminantes orgánicos persistentes en aceites de pescado con finalidad alimentaria. Se han desarrollado los métodos de análisis necesarios para la correcta determinación de estos compuestos en la matriz de estudio. Se han evaluado con detalle las etapas de purificación de la muestra, fraccionamiento de los analitos y análisis instrumental. El método ha sido validado con resultados satisfactorios, y se ha comprobado su buen funcionamiento mediante ejercicios de intercalibraje, así como la realización de diversos estudios con muestras reales de aceite de pescado. Se ha estudiado la eliminación de los contaminantes persistentes mediante adsorbentes sólidos con base silícica y carbonacea. Las condiciones experimentales han estado estudiadas en profundidad mediante diseños de experiencias y de evolución. Los mejores resultados se han obtenido con carbón activo, que demuestra una elevada eficacia en la eliminación de PCDD/Fs, dl-PCBs y HCB. Se ha estudiado la eliminación de los contaminantes orgánicos persistentes mediante técnicas de degradación fotoquímica. Inicialmente se ha fotodegradado cada familia de contaminantes por separado, para poder estudiar más a fondo las condiciones necesarias para su eliminación. Posteriormente se ha estudiado la degradación simultánea de los analitos de interés en aceite de pescado. Esta técnica se ha mostrado efectiva en la eliminación de DDT, PBDEs, HCB y PCBs similares a dioxinas. Paralelamente a los estudios de eliminación mediante adsorbentes sólidos y técnicas fotoquímicas, se ha comprobado la calidad de los aceites de pescado antes y después del tratamiento. El proceso de adsorción en sólidos no afecta significativamente a la calidad del aceite, mientras que las técnicas fotoquímicas degradan una parte de los ácidos grasos insaturados. Se ha estudiado la eliminación de contaminantes orgánicos persistentes en aceites de pescado mediante la combinación de las dos técnicas estudiadas anteriormente, con una primera etapa de degradación fotoquímica y una segunda etapa de adsorción. Se han comparado los resultados finales de eliminación que se obtienen con cada uno de los métodos desarrollados. La adsorción en carbón activo es el proceso más adecuado para la eliminación de COPs en aceite de pescado. Se ha realizado un estudio de los niveles diastereoisoméricos y enantioméricos de un contaminante emergente –HBCD- en aceite de pescado. Se ha evaluado su capacidad de eliminación de la matriz de estudio mediante adsorbentes con base carbonacia y degradación fotoquímica, siendo principalmente eliminado por la segunda vía.
During the present doctoral thesis several methods for the elimination of persistent organic pollutants from fish oil have been studied. Analytical methodologies for the determination of these compounds in fish oil have been developed. Sample purification, fractionation of the analytes and instrumental determination steps have been deeply studied. The method has been validated with satisfactory results, and its performance has been verified through its participation in several intercalibration exercises and studies with real fish oil samples. Elimination of persistent organic pollutants with silicon and carbon-based adsorbents has been studied. The experimental conditions have been studied in depth with an experimental design, to finally optimize the adsorption method using an evolutionary design. Best results have been obtained with the active carbon, showing high efficiency of the removal of PCDD/Fs, dioxin-like PCBs and HCB. Elimination of persistent organic pollutants with photochemical degradation techniques has been studied. Initially, each family of pollutants has been photodegraded separately, to determine its degradation conditions, as well as degradation mechanisms and by-products. Later, simultaneous photodegradation of the analytes has been studied in fish oil. This technique has shown high efficiency on the degradation of DDT, PBDEs, HCB and dioxin-like PCBs. The quality of the oils before and after the treatments with solid adsorbents and photochemical degradation has also been studied. The adsorption process does not significantly affect the quality of the oils, while photochemical techniques can degrade the unsaturated fatty acids. Elimination of persistent organic pollutants in fish oil combining adsorption in solids and photochemical degradation has been studied. Results obtained with each of the developed methodologies (adsorption, photodegradation and combined method) were compared. Adsorption in active carbon is the most suitable process for COPs elimination in fish oil. Finally, diastereoisomeric and enantiomeric levels of an emerging pollutant –hexabromocyclododecane (HBCD)- in fish oil have been studied. Its elimination has been evaluated with carbon-based adsorbents and photochemical degradation, being mainly eliminated with the photodegradation techniques.
Luo, Peng [Verfasser]. "Essays on Multidimensional BSDEs and FBSDEs / Peng Luo". Konstanz : Bibliothek der Universität Konstanz, 2015. http://d-nb.info/1109923309/34.
Texto completoBrown, Rebecca A. (Rebecca Ann) 1976. "Large strain deformation of PETG as processing temperatures". Thesis, Massachusetts Institute of Technology, 2000. http://hdl.handle.net/1721.1/88847.
Texto completoStoffle, Richard W., Vlack Kathleen A. Van, Phillip Dukes, Sola Stephanie De y Hannah Johnson. "Solar PEIS Native American Ethnographic Study Photographic Collection". Bureau of Applied Anthropology, University of Arizona, 2013. http://hdl.handle.net/10150/301158.
Texto completoBilly-Rouis, Danielle. "La médiation par le PEI". Lyon 2, 2002. http://theses.univ-lyon2.fr/documents/lyon2/2002/billy_d.
Texto completoThe concept of health, a purely medical entity of the standards in our society has informed our health care system and led this off-market sector into an economic logic which public authorities have been preoccupied with and which has, in the mean time, increased inequalities between individuals in access to medical treatment. It is our duty to restore its noble value and admit its vital dynamics within interdisciplinary connections. The PEI –Instrumental Enrichment Programme- set up by Reuven Feuerstein, is a pedagogic method and has been our working materiel. It is based on rigorous scientific basis. Mediation is a type of relation which is closely linked to and interdependent on it. Its complex function generates a great amount of adjustment processes to the functional realities of the moment. Our public ridden with handicaps, weakened by the present cuts seem to meet the needs of our work in a globalising prospect towards teaching methods in autonomisation. This thesis is based on the philosophical concept of the individual and deals with a limited methodological experience. It has no other aim but to raise some questioning and open perspectives. Health education calls for change in cultural habits which the public out of innocence, or medical service providers out of economic motives, are at present unable to bring about
Billy-Rouis, Danielle Avanzini Guy. "La médiation par le PEI". Lyon : Université Lumière Lyon 2, 2002. http://demeter.univ-lyon2.fr:8080/sdx/theses/lyon2/2002/billy_d.
Texto completoČervenka, Jiří. "Povrchová analýza nanokompozitu xGnP/PEI". Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2012. http://www.nusl.cz/ntk/nusl-216900.
Texto completoNAKAMURA, Toshio, Shinya NAKAMURA, Hiroshi NISHIMOTO, 俊夫 中村, 晋也 中村 y 寛. 西本. "PEG含浸木材のGC/MSによる残存PEG測定". 名古屋大学年代測定資料研究センター, 2011. http://hdl.handle.net/2237/16519.
Texto completoWieslander, Ida, Lisa Bonell y Ida Ström. "Nyttoanalys i investeringsbedömning : En fallstudie utifrån PENG-modellens metodik". Thesis, Växjö University, School of Management and Economics, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:vxu:diva-1823.
Texto completoBakgrund: Enligt flera författare råder en problematik kring IT-investeringar jämfört med andra typer av investeringar. Forskning visar på att de traditionella metoder som används vid investeringar inte mäter det riktiga värdet vid investering i IT. Beslutsfattare och forskare har vidare fört på tal att traditionella värderingsanalyser är ofullständiga när det gäller IT-investeringar då kostnader och nyttor som borde ingå i en IT-investeringsanalys inte tas med. Resultatet av detta blir då att det ser ut som att många IT-projekt inte återbetalar sig och därför inte är lönsamma.
Syfte: Huvudsyftet med studien är att öka kunskapen om användbarheten i PENG-modellens metodik vid utvärdering av investeringar i IT-system. Studiens delsyften är dels att kartlägga och testa PENG-modellens metodik vid investering i ett specifikt driftsuppföljningssystem på två tillverkande företag och dels att utvärdera ändamålsenligheten genom att identifiera modellens fördelar, nackdelar samt risker.
Metod: Nyttoanalyser efter PENG-modellens metodik har genomförts som en fallstudie på två företag. Enligt metodiken har ett förberedande möte och tre analysmöten genomförts där sista analysmötet avslutades med en utvärdering av metodiken utifrån deltagarnas åsikter och uppfattningar. Det empiriska materialet har sedan analyserats i relation till teori om investeringsbedömning, IT-investeringar och PENG-modellen.
Slutsatser: Studiens slutsatser är att PENG-modellens metodik är ändamålsenlig vid mer komplexa investeringar, givet att hänsyn tas till vikten av gedigna förberedelser där investeringen och vilka områden den berör kartläggs. Samtidigt är det av stor betydelse att rätt deltagare engageras för att resultatet ska bli så realistiskt som möjligt. PENG-modellens främsta fördel för företag i ett tidigt stadium i investeringsprocessen är den lärande effekt som uppkommer under diskussionerna i analysens faser. Resultatet av nyttoanalysen kan inte ersätta en traditionell investeringskalkyl men däremot utgöra ett bra underlag för beräkningen.
Liu, Peng [Verfasser]. "Three Essays in Empirical Macroeconomics and Finance / Peng Liu". Bonn : Universitäts- und Landesbibliothek Bonn, 2019. http://d-nb.info/1194464718/34.
Texto completoPeng, Wentao [Verfasser]. "Binary Planet–Satellite Nanostructure Using RAFT Polymer / Wentao Peng". Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2020. http://d-nb.info/1234846802/34.
Texto completoGaland, Marie-France. "Les Militantes du SNI-PEGG de 1945 à 1981". Lille 3 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb376052542.
Texto completoHodgskiss, Dean Leslie. "Does the PEG ratio add value?" Diss., University of Pretoria, 2012. http://hdl.handle.net/2263/29795.
Texto completoDissertation (MBA)--University of Pretoria, 2012.
Gordon Institute of Business Science (GIBS)
unrestricted
Qiao, Hong. "Robotic peg-hole insertion operation analysis". Thesis, De Montfort University, 1994. http://hdl.handle.net/2086/13276.
Texto completoEllsworth, Todd, David Robinson y Albert Dobrenz. "PEG-Induced Stress on Alfalfa Seedlings". College of Agriculture, University of Arizona (Tucson, AZ), 1987. http://hdl.handle.net/10150/203793.
Texto completoMatuschke, Jannik [Verfasser], Martin [Akademischer Betreuer] Skutella, Britta [Akademischer Betreuer] Peis y Thomas [Akademischer Betreuer] McCormick. "Network flows and network design in theory and practice / Jannik Matuschke. Gutachter: Martin Skutella ; Britta Peis ; Thomas McCormick. Betreuer: Martin Skutella ; Britta Peis". Berlin : Technische Universität Berlin, 2014. http://d-nb.info/1065666071/34.
Texto completoMatuschke, Jannik [Verfasser], Martin Akademischer Betreuer] Skutella, Britta [Akademischer Betreuer] [Peis y Thomas [Akademischer Betreuer] McCormick. "Network flows and network design in theory and practice / Jannik Matuschke. Gutachter: Martin Skutella ; Britta Peis ; Thomas McCormick. Betreuer: Martin Skutella ; Britta Peis". Berlin : Technische Universität Berlin, 2014. http://nbn-resolving.de/urn:nbn:de:kobv:83-opus4-47852.
Texto completoWredenberg, Daniel y Marcus Bengtsson. "Evaluationof IT-investments : A case study of the PENG-model". Thesis, Jönköping University, JIBS, Business Informatics, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-1118.
Texto completoThree senior consultants, that primary work with organisational development and project management has created a model, named PENG, specially adjusted for evaluation of IT-investments. The purpose of this model is to evaluate both the financial and the “softer” values of IT. According to IT’s major role of supporting the business concept, “soft” val-ues like; improved customer service, fewer complaints, more reliable deliveries and et cetera becomes very important. An interesting feature of the PENG-model is that it promises to, as the name indicates (PENG means coin in Swedish), transform all aspects of IT into monetary terms. This makes it possible to quantifiably measure all the aspects of IT, not just the ones that can be counted for as reduced costs. This attribute makes PENG different compared to other models that we have found. In this thesis we have chosen to study how the use of PENG affects evaluations of IT-investments, by focusing on both restricting and enabling aspects.
The studies that have been performed are mainly based on qualitative methods. We have used a literature study to see which aspects that are of most importance when evaluating IT. Further on we have studied descriptions, by the originators of PENG, to see how an actual evaluation process is supposed to be done. Based on this we have performed an in-terview at Kalmar county council, who have used and are using the model in several of their IT-projects, in order to see how PENG serves in real life situations.
We have found out that the PENG-model certainly has good intentions in capturing the complexity inherent in IT, by valuing “soft” and “hard” aspects and for illustrating an in-vestment from different perspectives. The model involves a working procedure consisting of ten steps that serves as a guideline for the evaluator. However, the model lacks a clear framework describing how the actual work in each step shall be performed.
The model generates in a clear and easily understandable result that can be understood through out the organisation, this mostly due to the use of money as the unit of measure-ment. The quality of the result is however largely dependent on the judgements of the persons involved. Depending on how you value the benefits and costs of IT, you will end up with diverse results. From this, we can see that the model has problems in terms of trustworthiness. We believe that PENG, despite its credibility issues, can be useful when discussing IT in order to illustrate the implications of an investment. We can also see the worth of the model when comparing different kinds of IT-investments; to see where the money can be of best use. The study further shows that PENG can be used in any type of organisation, even though it may be better suited for the public sector, where “soft” bene-fits are an essential part of the business concept.
Tre senior konsulter som primärt arbetar med organisationsutveckling och projektstyrning har tagit fram en modell speciellt utvecklad för utvärderingar av IT-investeringar. Modellen heter PENG och har som syfte att utvärdera både finansiella och kvalitativa aspekter av IT.
Då IT har som primärt syfte att stödja kärnverksamheten, så blir ”mjuka” aspekter såsom, ökad kundservice, färre klagomål, säkrare och mer spårbara leveranser et cetera mycket viktiga. En intressant egenskap som PENG-modellen besitter är att den utlovar att, som namnet antyder, värdera alla aspekter av IT i monetära termer. Detta skapar möjligheter att kvantitativt mäta IT:s totala påverkan i en organisation, vilket gör denna modell annorlunda från övriga modeller som vi har funnit. Denna uppsats har som syfte att studera hur användandet av PENG-modellen påverkar utvärderingen av IT-investeringar.
Studien är baserad på kvalitativ metodik. Till att börja med har vi genomfört en litteratur-studie för att undersöka vilka aspekter som skiljer en IT-investering från andra typer inve-steringar, samt för att ta reda på vad som krävs för att en IT-utvärdering skall bli så rättvisande som möjligt. Efter detta har vi studerat beskrivningar, gjorda av upphovsmännen bakom PENG, för att undersöka hur modellen är tänkt att användas. Baserat på detta har vi sedan genomfört en intervju vid Kalmar läns landsting, vilka har använt och fortfarande använder sig av denna modell i flera av sina IT-projekt, för att undersöka hur väl modellen fungerar i realiteten.
Baserat på detta drar vi slutsatsen att PENG-modellen har goda intentioner i att återspegla komplexiteten i IT, genom att värdera ”mjuka” och ”hårda” nyttor och att beskriva investeringar från olika perspektiv. Modellen består av tio steg som syftar till att guida utvärderaren genom hela processen. Modellen saknar dock tydliga riktlinjer som beskriver hur varje steg av utvärderingen skall gå till och många beslut blir därför godtyckliga.
Modellen generar i ett klart och lättförståeligt resultat, vilket beror på att alla aspekter av IT omvandlas till kronor. Kvaliteten på resultatet är dock till stor del beroende av de bedömningar som de involverade personerna gör under utvärderingsprocessen. Beroende på hur nyttor och kostnader av IT värderas så kommer detta att resultera i olika resultat. Av detta drar vi slutsatsen att modellen har trovärdighetsproblem. Vi menar dock att mo-dellen, trots detta, kan vara användbar för att illustrera innebörden av IT-investeringar. Vi kan också se att modellen har potential att jämföra olika IT-investeringar, i syfte att utvärdera var pengarna kan komma till störst nytta. Vidare visar vår studie att PENG kan användas i alla typer av organisationer, även om den troligen är bäst lämpad för den offentliga sektorn, där ”mjuka” nyttor är en viktig del av kärnverksamheten.
Peiß, Matthias [Verfasser]. "Essays about social categorization effects on economic behavior / Matthias Peiß". Magdeburg : Universitätsbibliothek, 2017. http://d-nb.info/114123050X/34.
Texto completoPeiss, Matthias [Verfasser]. "Essays about social categorization effects on economic behavior / Matthias Peiß". Magdeburg : Universitätsbibliothek, 2017. http://d-nb.info/114123050X/34.
Texto completoSyu, Ming Chen y 許明禎. "Co-delivery platform based on rGO-PEI/PEG nanocomplex". Thesis, 2016. http://ndltd.ncl.edu.tw/handle/s2c7r4.
Texto completo國立清華大學
生醫工程與環境科學系
105
Gene therapy is a process of introducing foreign genomic materials into target cells to elicit a therapeutic benefit. A diverse array of inherited and acquired diseases are targets of gene therapy. To overcome the multidrug resistance (MDR), one of the major impediment against curative cancer chemotherapy, the application of small interfering RNA (siRNA) provide a new opportunity for specific gene-silencing of MDR-associated proteins. In this study, a simple and novel approach is presented for constructing a dual delivery vector through a one-pot hydrothermal reaction, using graphene oxide (GO), polyethylenimine (PEI) and polyethylene glycol (PEG) as starting materials. The resulting nanoplatform, rGO-PEI/PEG exhibited minimal toxicity and could effectively complex siRNA at a W/W ratio above 3.4. Additionally, rGO-PEI/PEG was capable of high drug loading (doxorubicin, ~0.49 mg/mg) and photothermally triggered cytosolic drug delivery. With optimal near-infrared laser irradiation, the drug-loaded rGO-PEI/PEG demonstrated an enhanced antitumor efficacy in cancer cells through combined photothermal effect and chemotherapy. The synergistic potential of dual drugs (doxorubicin and siRNA)-loaded rGO-PEI/PEG in combination with laser irradiation will next be explored to augment the therapeutic effect in MDR cancer cells. The advances described above will complement our knowledge of graphene functionality and serve to guide its application in gene/drug delivery.
Chang, Jung y 張蓉. "Lipo-PEG-PEI complex encapsulated antitumor drug for colorectal cancer therapy". Thesis, 2015. http://ndltd.ncl.edu.tw/handle/4f6787.
Texto completo國立交通大學
生物科技學系
103
CR1 is a derivative of the plant lignan nordihydroguaiaretic acid (NDGA). It has been proposed that the parent compound and its derivatives inhibit the interaction between the transcription factor Sp1 and its DNA-binding site via DNA groove-binding. Furthermore, Sp1 has highly related to colorectal cancer development and progression. Therefore, CR1 is a potential anticancer agent in colorectal cancer therapy, but CR1 also has side effect to normal tissues. Because of its high cytotoxicity, liposome encapsulation may reduce the cytotoxicity of CR1 to normal tissues, but keep the cytotoxicity for tumor cells. Colorectal carcinoma, cancer of the colon and rectum, is the second leading cause of cancer death worldwide in women and the third leading cause of cancer death worldwide in men. Nowadays, therapy of colorectal cancer is only moderately successful for late-stage and is often limited by severe side effects and dose limiting toxicity. Hence, it is needed a new chemotherapy agent in colorectal cancer. My purpose is to use Lipo-PEG-PEI complex (LPPC) encapsulated CR1 to reduce cytotoxicity in normal tissues, and improve therapeutic efficacy for colorectal cancer. In my results, the protocol for the formation of LPPC/CR1 was optimal. LPPC/CR1 had an average size less than 200 nm and a zeta potential of approximately 35 mV. In addition, this study also showed the antitumor effects of LPPC/CR1 for colorectal cancer in vitro and in vivo. These results indicate that the LPPC/CR1 complex may supply a feasible strategy for the advanced colorectal cancer therapy in the future.
Weiss, Sabine [Verfasser]. "Uronsäure-funktionalisierte PEI- bzw. PEI-PEG-Konjugate und artifizielle Chromosomen für den nicht-viralen Gentransfer / vorgelegt von Sabine Isabella Weiss". 2006. http://d-nb.info/983063931/34.
Texto completoChen, Chia-Hung y 陳家弘. "The manipulation of lipo-PEG-PEI complex for immunoregulation and intracellular protein delivery". Thesis, 2013. http://ndltd.ncl.edu.tw/handle/66749867246624487719.
Texto completo國立交通大學
分子醫學與生物工程研究所
101
Liposomes (phospholipid bilayer vesicles), which are biocompatible and flexible biomaterials, are currently used for efficient induction of specific immune responses against antigens. In our laboratory, lipo-complex has been developed and proved that (1) its non-covalent protein-adsorption ability, (2) the bound proteins are irreplaceable and (3) maintain the activities of the bound proteins. In this study, according to the characters of lipo-complex, the aim is the investigation of immunoregulation and intracellular protein delivery by using lipo-complex. Section one is to demonstrate that lipo-complex adsorbed immunofunction proteins could regulate specific T-cell immunity in vivo. Section two is to evaluate that the immunoregulation effect of lipo-complex is on the mice immunity against B16F10-pLEGFP melanoma cells in metastatic model. Section three is to investigate that the intracellular protein delivery ability and its mechanism of lipo-complex. Therefore, the study of lipo-complex provides an insight on the potency of development of personalized medicine and protein drug.
-chen, Che y 林哲震. "Protecting effect of DNA in polycation(PEI) by PEG and spray-drying technology". Thesis, 2009. http://ndltd.ncl.edu.tw/handle/gepggv.
Texto completo嘉南藥理科技大學
生物科技系暨研究所
97
Spray-drying method has been used for development of biotechnological protein preparation and preservation. The characteristic of spray-drying method is able to remain in particle form and keep dryness simultaneously. Using a single process to remove water from the original solution and obtain solid particle preparation attracts great interest by biopharmaceuticals. To preserve high molecular polycation/DNA complex by freeze-drying method has been identified and demonstrated to retain stability of DNA gene expression at least over one year. However, spray-drying method has not been extensively studied. The aims of this study are to investigate the factors that influence PEI/DNA transfection efficiency after spray-drying process and to evaluate protective efficiency of two different types of protective agents. To investigation of transfection efficiency, polyethyleneimine(PEI)/DNA complex (the ratio is 1:1) was used as a criterion of gene transfection. Sucrose and PEG 4000, 10000, and 35000 were used as the protective agents in different ratios (5, 10, 20 and 30%) to form a secondary complex with PEI/DNA complex or become a mixture with DNA and PEI separately prior to make PEI/DNA complex. These complexes were then subsequently subjected to spray-drying process. The spray-drying products were then reconstituted and performed gene tranfection study. Their cytotoxicity and gene expression in agarose gel was also studied. When naked plasmid DNA mixed with non-condense neutral protective agents after spray-drying process, most of DNA tertiary structure remained in open circular. Since 10%of all PEG mixed with PEI/DNA complex generated highest products, easily to be dissolved in water and possessed higher transfection efficiency, this mixing ratio was chosen for further studies. Results of transfection efficiency from fresh made PEI/DNA mixed with PEG 4000 was comparable to PEI/DNA complex. However, the efficiency was abolished after spray-drying process. Neither fresh prepared nor spray-drying prepared PEI/DNA mixed with other protective agents in either preparation methods show any significant transfection. Cell viability showed that all preparation were not-toxic to cells. Gene expressed in agarose gel also confirmed that protective agents could not be separated by polyaspartic acid from PEI/DNA complex after spray-drying process, subsequently affecting the transfection. In conclusion, spray-drying process may be an easy method to perverse many types of material, it is not suitable for current chosen protective agents, in terms of reservation of their bioactivity. In the future work, we intend to find other better protective agents for this preserving process.
Germershaus, Oliver [Verfasser]. "Non-viral gene delivery systems : studies on HER2-targeted PEG-PEI copolymers and modified chitosans / vorgelegt von Oliver Germershaus". 2008. http://d-nb.info/991590139/34.
Texto completoGAO, DA-PENG y 高大鵬. "GAO, DA-PENG". Thesis, 1985. http://ndltd.ncl.edu.tw/handle/16660111436874027422.
Texto completoPENG, HUAN-XU y 彭煥勛. "PENG, HUAN-XU". Thesis, 1985. http://ndltd.ncl.edu.tw/handle/26417233514668410152.
Texto completoJIANG, PENG-SHENG y 江澎生. "JIANG, PENG-SHENG". Thesis, 1985. http://ndltd.ncl.edu.tw/handle/90820661615245489908.
Texto completoYI, CHENG-PENG y 尹承蓬. "YI, CHENG-PENG". Thesis, 1985. http://ndltd.ncl.edu.tw/handle/78279542840464781405.
Texto completoLin, Shih-Chun y 林士鈞. "Special Protection System for Peng-Hu Offshore Wind Farm and Tai-Peng Submarine Cables". Thesis, 2006. http://ndltd.ncl.edu.tw/handle/20584205548407555112.
Texto completo中原大學
電機工程研究所
94
Peng-Hu is an isolated power system without having any links with Taiwan. There is only a Gen-San power plant with 12 diesel generators located in the main island. According to the load increasing, Peng-Hu power system need to build new plants, including diesel generator, wind power generator, offshore wind farm, and submarine cables that connect Peng-Hu power system with Taiwan. By the possibility of set up the new plants, that could have nice situations. After generators and submarine cables incorporating into the power system, it caused impacts in all respects. So this study considered evaluating every phenomenon, such as voltage fluctuation, voltage flicker, harmonic, safety of system, transient stability, underfrequency load shedding and overfrequency generator tripping. For discussing the Peng-Hu power system’s transient stability, this study established the exciter and governor’s mathematic model of the diesel and wind generator. Because of wind couldn’t be forecasted, the large-scale offshore wind farm caused voltage flicker in the power system. This study considered nine system situations in 2011. It used PowerWorld Simulator to study the power flow and fault current, and using PSCAD/EMTDC to study voltage flicker and transient stability. By the strategy of the special protection system, planning the underfrequency load shedding and overfrequency generator tripping. Certain of the advantageous results toward building the every new plant are also provided in this paper.