Tesis sobre el tema "PDMS-based"
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Vila, i. Planas Jordi. "PDMS-based opto uidic systems". Doctoral thesis, Universitat Autònoma de Barcelona, 2014. http://hdl.handle.net/10803/284136.
Texto completoAlong the thesis, several optics and fluidics elements are succesfully integrated in fully functional optouidic systems. Integration of these elements using soft-lithography fabrication technique and PDMS as constituent material ensures low-cost, disposable and flexible LOCs systems. Developed elements are individually characterized and LOCs are characterized and tested as (bio)chemical tools to overcome unsolved issues of the present state of the art in LOC applications. Design, optimization, fabrication and characterization of individual optical elements is outlined. Optical elements have been divided in two categories, passive and active elements. Passive elements are those which do not require an energy source to work. Firstly, the most simple elements, i.e., collimation lenses and self-alignment structures, necessary to create more complex structures. Such elements usually were published previously, but our development and optimization of elements as well as auxiliary structures, e.g., stoppers and self-alignment channels, built using a single technology with no increase of fabrication steps, provide a robust approach to create more complex structures. Air mirrors and lenses are combined to create beam splitters. The major issue of the BS is the deviation of output power between channels. This result suggests that some misalignment in the fibre position, the lens collimation or the waveguide geometry has occurred. Using developed MIMIC variations a new passive optical element are designed, fabricated and characterized. PDMS doped with three different pigments are used to create filters with stopbands along the whole visible spectrum. Finally, an active element, an integrated emitter, is redesigned using TracePro simulation software. Simulation results suggest there are dead volumes inside the emitter chamber. Then, size reduction and shape change is proposed. Integration of many of the these optical plus some fluidic elements is explained. Firstly, different connectors between modules are designed and tested. The previously redesigned integrated emitter are manufactured and characterized. Its behaviour matches with simulations results and suggest a further size reduction is not only possible but also recommendable. All the modules are fabricated from two PDMS replicas. Each module is elastic and can be assembled with other modules in any substrate, modules connections are not permanent and can be plug and unplug with no previous knowledge in microfluidics or LOC. Hence, presented modular system have enough flexibility to create LOC on demand to researchers without the background required to design and manufacture LOC systems from scratch. In order to prove it several modules are tested together in a crystal violet concentration determination. Previously reported collimation lenses are monolithically integrated in a monodisperse microdroplets generator. Two different optical configurations have been proposed in order to make possible fluorescence and absorbance measurement of droplets. Both are tested and compared to previous set up with equivalent results. In addition, proposed configurations can detect unlabelled droplets, a feature that was not possible with the previous set up, with the same precision and reliability. However, due to our collimation lenses and readout equipment, the droplet generation rate is limited to 160 drops/s. Finally, screening of droplet inner medium is experimentally proved for first time in optofluidic system. Afterwards, a compact and integrable fluidically controlled optical router (FCOR) is build using soft-lithographic techniques and made entirely of PDMS and air ensuring low-cost and robustness. Phaseguides, has been exploited to create a FCOR with a movable mirror without mobile parts. The LOC is repetitive, and has a good durability (non appreciable degradation or performance deterioration for weeks, in the whole visible spectrum). Finally, FCOR is integrated in a previously reported LOC performing parallel measurements of glucose and lactate with a single light source. After setup calibration, the FCOR allows parallel measurement of glucose and lactate showing good agreement with previous results. Validating then, the FCOR for parallel analysis.
Ozkan, Ekrem. "PDMS-based antimicrobial surfaces for healthcare applications". Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10044839/.
Texto completoLamperti, Emanuele. "PDMS based microfluidics membrane contactors for CO2 removal applications". Master's thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amslaurea.unibo.it/15261/.
Texto completoSommer, Stacy Ann. "Siloxane-Polyurethane Fouling-Release Coatings Based On PDMS Macromers". Diss., North Dakota State University, 2011. https://hdl.handle.net/10365/29313.
Texto completoOffice of Naval Research (U.S.)
Gong, Xiuqing. "PDMS based microfluidic chips and their application in material synthesis /". View abstract or full-text, 2009. http://library.ust.hk/cgi/db/thesis.pl?NSNT%202009%20GONG.
Texto completoSamel, Björn. "Novel Microfluidic Devices Based on a Thermally Responsive PDMS Composite". Doctoral thesis, KTH, Mikrosystemteknik, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4470.
Texto completoQC 20100817
Samel, Björn. "Novel microfluidic devices based on a thermally responsive PDMS composite /". Stockholm : Kungliga Tekniska högskolan, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4470.
Texto completoTabarizadeh, Elham. "PDMS-based membranes for dehydration of Triethylene glycol using pervaporation technology". Master's thesis, Alma Mater Studiorum - Università di Bologna, 2018.
Buscar texto completoForster, Simon. "Surface modification of PDMS-based microfluidic devices through plasma polymerisation : production and application". Thesis, University of Sheffield, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.531221.
Texto completoAbraham, Berhane Teclesenbet. "Degradation and recovery of polydimethylsiloxane (PDMS) based composites used as high voltage insulators". Thesis, Stellenbosch : Stellenbosch University, 2004. http://hdl.handle.net/10019.1/49902.
Texto completoENGLISH ABSTRACT: Polydimethylsiloxane (PDMS) compounds are utilized in outdoor high voltage insulation due to their low weight, vandalism resistance, better anti-contamination performance and their superior hydrophobic nature. Under severe environmental conditions and over prolonged service time, however, the hydrophobic surface can gradually become hydrophilic and then recover with adequate resting period. In this study, room temperature vulcanized (RTV) PDMS samples were prepared with different formulations and then exposed to corona discharge to evaluate its effect. The influence of different additives, such as different types and amount of fillers and additionally added low molar mass silicone oils, on the hydrophobicity recovery of the material was investigated. The effects of two types of corona treatment were also evaluated. Hydrophobicity recovery of corona and UV-C aged PDMS samples was evaluated by means of static contact angle measurements. Positron annihilation spectroscopy (PAS) gave important information on the micro structural change after corona treatment of RTV PDMS as well as naturally aged high temperature vulcanized (HTV) PDMS samples. The different formulations of the RTV PDMS samples and the effect of the additives were studied with this technique. The formation of a thin, highly crosslinked inorganic silica-like (SiOx) layer was confirmed even at the early stage of degradation. It was also possible to estimate the thickness of the silica-like layer formed during corona exposure that is responsible for the loss and recovery of hydrophobicity. The surface hardness and hydrophilicity change of PDMS samples due to corona treatment were studied simultaneously with force distance measurements by atomic force microscopy (AFM). The adhesive force calculated from the pull-off force-distance curves showed that the adhesive force between the probe and the sample decreased with increasing corona treatment time, indicating hydrophobicity recovery. In addition to this, the increase in hardness after corona exposure provides indirect evidence of the formation of a silica-like layer. In all cases the hydrophilicity and the surface hardness of the PDMS samples increased directly after corona treatment and recovered with time. Two types of FTIR spectroscopy were used to analyse the surface of the polymer.
AFRIKAANSE OPSOMMINGS: Polidimetielsiloksaan (PDMS) word in buitelug hoogspanninginsulasie gebruik as gevolg van sy lae massa, weerstand teen vandalisme, verbeterde anti-kontaminasie werkverrigting en superieure hidrofobiese karakter. Die hidrofobiese oppervlakte kan egter gelydelik hidrofillies word onder uiterste omgewingsomstandighede en oor langdurige dienstyd. PDMS materiaal herstel egter nadat dit genoeg rustyd toegelaat is. Kamertemperatuur-gevulkaniseerde (KTV) PDMS met verskillende formulasies is in hierdie studie voorberei, aan korona ontlading blootgestel, geëvalueer en vergelyk. Die invloed van bymiddels soos verskillende tipes en hoeveelhede vuiler, asook addisionele lae molekulêre massa silikoonolie, op die herstel van hidrofobisiteit van die materiaal is ondersoek. Twee verskillende metodes van korona behandeling is ook geëvalueer. Die herstel van hidrofobisiteit van korona en UV-C verouderde PDMS monsters is met statiese kontakhoekmeting geëvalueer. Positronvernietigingspektroskopie (PVS) is 'n kragtige tegniek wat belangrike inligting oor die mikrostrukturele verandering van korona behandelde van KTV PDMS sowel as natuurlik-verouderde hoë temperatuur gevulkaniseerde (HTV) PDMS monsters gee. Die verskillende formulasies van die KTV PDMS monsters, sowel as die effek van die vullers, is met behulp van hierdie tegniek ondersoek. Die vorming van 'n dun, hoogskruisgebinde, anorganiese silika-agtige (SiOx) laag op die PDMS oppervlak, selfs tydens die vroeë stadium van degradasie, is bevestig. Dit was ook moontlik om die dikte van die silika-agtige laag wat gedurende die korona blootstelling gevorm het, en wat verantwoordelik is vir die verlies aan hidrofobisiteit, te bepaal. Die oppervlakhardheid en hidrofilisiteit verandering van PDMS monsters as gevolg van korona behandeling, was gelyktydig met krag-afstand metings deur middel van atoomkragmikroskopie (AKM) bestudeer. Die kleefkrag, soos bereken van aftrek kragafstandkurwes, dui daarop dat kleefkragte tussen die taster en die monster afneem met toenemende korona behandelingstyd, wat beduidend is op die herstel van hidrofobisiteit. Daarbenewens is die toename van oppervlakhardheid na korona blootstelling "n indirekte bewys van die formasie van 'n silika-agtige laag. In alle gevalle het die hidrofilisiteit en die oppervlakhardheid van die PDMS monsters toegeneem direk na afloop van korona behandeling en gevolglik herstel met tyd. Twee tipes IR spektroskopie metodes is gebruik vir die chemiese-oppervlak analises
To, Josiah. "Developing a novel heterogeneous three electrode system for a PDMS-based microfluidic electrochemical sensor". Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/56174.
Texto completoApplied Science, Faculty of
Graduate
Yang, Cheng Wei Tony. "Adsorption of a carboxylated silane on gold : characterization and application to PDMS-based electrochemical cells". Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/58832.
Texto completoApplied Science, Faculty of
Chemical and Biological Engineering, Department of
Graduate
Ana, U. J. "The attainment of controlled adhesion by incorporation of low level additives in a PDMS-based adhesive". Thesis, Loughborough University, 2005. https://dspace.lboro.ac.uk/2134/7764.
Texto completoWang, Zhengmu. "Design, fabrication and characterization of a double-network alginate-pHEMA hydrogel coating for PDMS-based biomedical implants". Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/61102.
Texto completoApplied Science, Faculty of
Mechanical Engineering, Department of
Graduate
Cao, Hong Ha. "The fabrication process of microfluidic devices integrating microcoils for trapping magnetic nano particles for biological applications". Thesis, Paris 11, 2015. http://www.theses.fr/2015PA112150/document.
Texto completoIn this study, a concept of microfluidic chip with embedded planar coils is designed and fabricated for the aim of trapping effectively functionalized magnetic nanobeads and immobilizing antibody (IgG type). The planar coils as a heart of microfluidic chip is designed with criterion parameters which are optimized from simulation parameters of the maximum magnetic field, low power consumption and high power efficiency by FE method. The characterization of microcoils such as effectively nanobeads (300 nm) at low temperature (<37oC) is performed and confirmed. The channel network in PDMS material is designed for matching with entire process (including mixing and trapping beads) in microfluidic chip. A process of PDMS’s surface modification is also carried out in the assemble step of chip in order to limit the non-specific adsorption of many bio substances on PDMS surface. The microfluidic chip assemble is performed by using some developed techniques of reversible packaging PDMS microfluidic chip (such as stamping technique, using non-adhesive layer, oxygen plasma combining with solvent treatment). These packaging methods are important to reused microchip (specially the bottom substrate) in many times. The immobilization of antibody IgG-type is performed inside microfluidic chip following the standard protocol of bead-based ELISA in micro test tube. The result showed that IgG antibodies are well grafted on the surface of carboxyl-beads (comparing to result of standard protocol); these grafted antibodies are confirmed by coupling them with labeled second antibody (Fab-FITC conjugation)
Chan, Yau-kei y 陳佑祺. "Reducing the complications associated with emulsification in the use of polydimethylsiloxane (PDMS) based silicone oil in vitreous surgery by engineering approaches". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/196728.
Texto completopublished_or_final_version
Ophthalmology
Doctoral
Doctor of Philosophy
Sang, Shengbo [Verfasser], Hartmut [Akademischer Betreuer] Witte, Klaus [Akademischer Betreuer] Liefeith y Theodor [Akademischer Betreuer] Doll. "An approach to the design of surface stress-based PDMS micro-membrane biosensors - concept, numerical simulations and prototypes / Shengbo Sang. Gutachter: Klaus Liefeith ; Theodor Doll. Betreuer: Hartmut Witte". Ilmenau : Universitätsbibliothek Ilmenau, 2010. http://d-nb.info/1010814516/34.
Texto completoKukhta, Dziyana. "Metody přípravy buněčných transplantátů v kardiologii". Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2019. http://www.nusl.cz/ntk/nusl-400529.
Texto completoKwong, Brian. "Poly-dimethyl-siloxane based responsive structures". Thesis, Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/53018.
Texto completoMier, Alexandro Castellanos. "Poly(N-Isopropylacrylamide) based BioMEMS/NEMS for cell manipulation". [Tampa, Fla] : University of South Florida, 2006. http://purl.fcla.edu/usf/dc/et/SFE0001814.
Texto completoMukhtar, Husneni. "Development of compensated immersion 3D optical profiler based on interferometry". Thesis, Strasbourg, 2018. http://www.theses.fr/2018STRAD017/document.
Texto completoCoherence Scanning Interferometry (CSI) or White Light Scanning Interferometry (WLSI) is a well-established optical imaging technique for measuring the surface roughness and the shape of microscopic surfaces. The advantages are the nanometric axial sensitivity, a wide field of view (hundreds of μm to several mm) and the measurement speed (a few seconds to a few minutes). The technique is based on optical interferometry with a Linnik configuration which very difficult to adjust but it offers several advantages: higher numerical aperture objectives to improve spatial resolution; long working distance, because there is no need for any of the components in front of the lens; a polarized light mode configuration; contrasting fringes because of the possibility of modifying the optical pathways and the intensities of the two arms independently. While the use of a water-immersion objective gives the following advantages: to avoid the problems related to the adjustment between the formation of the fringes and the plane of formation of the image; and to minimize the difference in dispersion between the arms of the interferometer. In order to be able to measure in water mode and to obtain high lateral resolution samples of chemical and biological types, several challenges must be overcome such as balancing the OPD on both arms; finding and adjusting the good contrast fringes; finding and adapting a suitable water compensation of water in horizontal reference arm to operate a system in water
McClain, Maxine Alice. "Elastomer-based microcable electrodes for electrophysiological applications". Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/39606.
Texto completoWHITLOCK, PATRICK W. "SILICON-BASED MATERIALS IN BIOLOGICAL ENVIRONMENTS". University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1116264213.
Texto completoPussadee, Nirut. "Poly(dimethylsiloxane) Based Micro- and Nanofluidic Device Fabrication for Electrophoresis Applications". The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1268179904.
Texto completoMohan, Greeshma. "Silicone Elastomer-Based Combinatorial Biomaterial Gradients for High Throughput Screening of Cell-Substrate Interactions". Scholar Commons, 2015. http://scholarcommons.usf.edu/etd/5857.
Texto completoJo, Myeong Chan. "An Acoustic-based Microfluidic Platform for Active Separation and Mixing". Scholar Commons, 2013. http://scholarcommons.usf.edu/etd/4697.
Texto completoWang, Qian. "Elastomer-based Cellular Micromechanical Stimulators for Mechanobiological Study". The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1397610258.
Texto completoCashman, Mark Francis. "Siloxane-Based Reinforcement of Polysiloxanes: from Supramolecular Interactions to Nanoparticles". Thesis, Virginia Tech, 2020. http://hdl.handle.net/10919/100134.
Texto completoMaster of Science
Polysiloxanes, also referred to as 'silicones' encompass a unique and important class of polymers harboring an inorganic backbone. Polysiloxanes, especially poly(dimethyl siloxane) (PDMS) the flagship polymer of the family, observe widespread utilization throughout industry and academia thanks to a plethora of desirable properties such as their incredible elongation potential, stability to irradiation, and facile chemical tunability. A major complication with the utilization of polysiloxanes for mechanical purposes is their poor resistance to defect propagation and material failure. As a result polysiloxane materials ubiquitously observe reinforcement in some fashion: reinforcement is achieved either through the physical or chemical incorporation of a reinforcing agent, such as fumed silica, or through the implementation of a chemical functionality that facilitates reinforcement via phase separation and strong associative properties, such as hydrogen bonding. This research tackles polysiloxane reinforcement via both of these strategies. Facile chemical modification permits the construction PDMS polymer chains that incorporate hydrogen bonding motifs, which phase separate to afford hydrogen bond-reinforced phases that instill vast improvements to elastic behavior, mechanical and elongation properties, and upper-use temperature. Novel nanocomposite formulation through the incorporation of MQ nanoparticles (which observe widespread usage in cosmetics) facilitate further routes toward improved mechanical and elongation properties. Furthermore, with growing interest in additive manufacturing strategies, which permit the construction of complex geometries via an additive approach (as opposed to conventional manufacturing processes, which require subtractive approaches and are limited in geometric complexity), great interest lies in the capability to additively manufacture polysiloxane-based materials. This work also illustrates the development of an MQ-reinforced polysiloxane system that is amenable to conventional vat photopolymerization additive manufacturing: chemical modification of PDMS polymer chains permits the installation of UV-activatable crosslinking motifs, allowing solid geometries to be constructed from a liquid precursor formulation.
Martinez, Rivas Adrian. "Wafer scale integration of coulomb blockade-based nanobiosensors with microfluidic channels for label-free detection of cancer biomarkers". Toulouse, INSA, 2009. http://eprint.insa-toulouse.fr/archive/00000344/.
Texto completoDans cette thèse, nous proposons et démontrons un nouveau type de nanobiocapteur pour la détection de biomolécules à haute sensibilité et leur intégration à grande échelle (plaquette de 4 pouces). Le principe du nouveau nanobiocapteur électrique est basé sur la variation de conductivité électrique à travers des nano-îlots grâce au phénomène quantique appelé « blocage de Coulomb ». Les nano-îlots de nickel (~5nm de diamètre) sont placés entre les nano-électrodes interdigitées (IND) (~45nm de largeur). La conductivité de ces dispositifs à Jonctions Tunnel Multiples (MTJ) est modifiée par l’adsorption de biomarqueurs impliqués dans la tumorogènese. Les oncologues ont récemment isolé et caractérisé un nouveau fragment d’anticorps à chaîne simple (scFv) qui reconnaît sélectivement la forme active de RhoA. Ce biomarqueur potentiel a été trouvé surexprimé dans diverses tumeurs. Les fragments d’anticorps ont été adsorbés, par des liaisons de coordination, sur les nano-îlots de nickel. Ces fragments sont capables de reconnaître spécifiquement la forme active de RhoA. Nous avons étudié ce biomarqueur et validé la chimie de surface à base de nano-’îlots de nickel pour la détection sans marquage, en utilisant une microbalance à quartz (QCM). Puis, nous avons mis au point et adapté à notre dispositif une méthodologie innovatrice pour réaliser, à l’échelle d’une plaquette, des microcanaux basés sur du photoPDMS. La caractérisation électrique finale des dispositifs intégrés a été testée en temps réel et à flux biologique continu. La forme active de RhoA a été détectée en discriminant la forme inactive. En annexe, je présente mon opinion épistémologique et éthique sur la nanotechnologie
Terp, Megan Cavanaugh. "Improved Nanoparticle Preparation and Delivery Technology for DOTAP and Oligonucleotide Based Lipoplexes". The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1338301430.
Texto completoKim, Tae-Young. "Novel sol-gel titania-based hybrid organic-inorganic coatings for on-line capillary microextraction coupled to high-performance liquid chromatography". [Tampa, Fla] : University of South Florida, 2006. http://purl.fcla.edu/usf/dc/et/SFE0001833.
Texto completoWei-Ching, Fang y 方韋清. "Development of PDMS-based rotational Micropump". Thesis, 2014. http://ndltd.ncl.edu.tw/handle/84543439694566930608.
Texto completo國立屏東科技大學
材料工程研究所
102
This experiment used CO2 laser as the primary source of method to process the PMMA. The traditional Photolithography process was not applied, because the CO2 laser saves a significant amount of time and budget for manufacturing. PMMA (Polymethyl-Methacrylate) is processed to be used as a base for the peristaltic micropump. Next, the PDMS (Poly-di-methyl-siloxane) is poured onto the PMMA where it creates a seal for the micropump when it has been solidified. This experiment uses a motor reduction model and a cross rotor to control the flow of fluid inside micropump. The relationship of the voltage range and the rotation speed of the motor has been monitored. When the range of the motor is set from 0.5 V to 5.5 V, the rotation speed is directly proportional to the voltage, and will increase accordingly before the micropump has been installed. But after it has been installed into the system, the rotation speed decreased by an average of 50 rpm. The fluidic design of the micropump uses a cross rotor, and has the input and output on the right and left side respectively. When the input is on, the cross rotor closes the output, allowing fluid to flow in. As the rotor rotates, it pushes the fluid until the output is on and input is off, thus letting the fluid flows out. This experiment uses de-ionized water as the tester, before the micropump has been installed, 1 V allows the motor produces 60 rpm, while at 5 V, the motor produces 285 rpm. After the micropump has been installed, the rotation was too low to calculate when the voltage was set to 1 V, thus this experiment started at 2 V. At 2 V, the motor produced 65 rpm with the flow rate of 0.51 ml/min, and at 5 V, the motor produces 232 rpm with the flow rate of 1.22 ml/min. To test out the functionality of the micropump, this experiment used 95% ethanol, salad oil and 15W40 motor oil as testers. When the motor reaches the speed of 65 rpm, the flow rate of ethanol is 0.367 ml/min, salad oil is 0.116 ml/min and motor oil is 0.048 ml/min. When the speed of the motor is increased to 232 rpm, the flow rate of ethanol is 0.901 ml/min, salad oil is 0.724 ml and motor oil is 0.336 ml/min.
Su, Yu-Ren y 蘇昱仁. "High-Performance Magnetic Sensor Based on Microstructured PDMS". Thesis, 2017. http://ndltd.ncl.edu.tw/handle/58839484594955681576.
Texto completo國立臺灣大學
物理學研究所
105
Resistive magnetic sensors measure different resistance values at different magnetic fields, in which the magnitude of the magnetic field can be monitored. However, the magnetic field will decline quickly when the distance increases, so that the sensitivity of the sensor for the measurement of the change of magnetic field is greatly desirable. In this thesis, we propose a new approach by the integration of microstructured PDMS embedded with FeNi50 particles and to form a highly sensitive magnetic sensor. Several key factors combined together makes the performance possible. First, FeNi50 nanoparticles possess a very high magnetic susceptibility. Second, the microstructured PDMS has unique features of low viscoelasticity and low elastic resistance. Third, AgNWs have the characteristics of excellent conductivity, enabling to be very sensitive with the change of magnetic field. Fourth, this newly designed device can be operated under a very low operational voltage. Therefore, the magnetic sensor can be integrated with solar cells, and it even can work under room light illumination, which is very useful for the development of wearable devices. In addition, we have demonstrated that our magnetic sensor can be integrated with light emitting diodes and can be used to create touchless panel.
Lin, Min-Han. "PDMS (polydimethylsiloxane) Based Polymerase Chain Reaction Component Design". 2005. http://www.cetd.com.tw/ec/thesisdetail.aspx?etdun=U0001-2707200515463700.
Texto completoLin, Min-Han y 林旻翰. "PDMS (polydimethylsiloxane) Based Polymerase Chain Reaction Component Design". Thesis, 2005. http://ndltd.ncl.edu.tw/handle/63011026529983047608.
Texto completo國立臺灣大學
應用力學研究所
93
This thesis presents a new device to perform polymerase chain reaction (PCR) using polydimethylsiloxane (PDMS) polymer as disposable PCR channel. Particular feature in the device include gravity-fed, circularly reciprocating action to ensure the PCR reagent is in contact with a specific temperature region during the PCR cycle of three temperatures – 94oC, 55oC, 72oC. The PCR channel (3.5 mm width by 1 mm height) is fabricated by molding PDMS against a laser scriber engraved PMMA master, with a 4 µm thick parylene film coated on the PCR channel inner and outer surfaces to alleviate bubble formation at high temperature. Simulation, using ANSYS, of heat transfer of the device is also undertaken to aid the design of the device. Results from temperature measurement, using resistive temperature detectors (RTD) sensors, show that the reagent can be cooled down to 55oC (from 94oC ) in 30 sec, or heated up to 72oC and 94oC in 15 sec, in agreement with ANSYS predictions. PCR is demonstrated by a 773 bps DNA template, which is incubated at 94oC for 30 sec, 55oC for 1 min., and 72oC for 1 min. to perform DNA denaturation, primer annealing, and extension of DNA template, respectively. Using the present first-generation device, DNA amplification is clearly proven, however, the efficiency is not as good as commercial PCR machine. Evaporation in the reagent is believed to be the key problem that needs to be improved.
Li, Wei. "Dual function magnetic PDMS microsphere-based microfluidic valve and mixer". 2005. http://link.library.utoronto.ca/eir/EIRdetail.cfm?Resources__ID=370102&T=F.
Texto completoGu, Wei-guo y 古偉國. "Fabrication and properties of PDMS-based flow-through PCR device". Thesis, 2007. http://ndltd.ncl.edu.tw/handle/5zzz4a.
Texto completo大同大學
生物工程學系(所)
95
Polymerase chain reaction (PCR) utilizes DNA polymerase to amplify specific DNA fragment. The reaction is carried out under three different reaction temperatures, and the amplified DNA product can be used in subsequent analysis and research. In this thesis, a PDMS-based flow-though PCR device was fabricated using micro-fabrication techniques. The flow channel (50 μm deep) plate and a 1 mm-thick flat back plate were fabricated using PDMS, then the two plates were bonded after oxygen plasma treatment. A thin-film chromium resistive heater was manufactured on Corning 1737 glass substrate. The PCR device was assembled simply by placing the PDMS flow channel on the top of the glass heating chip. The cDNA of D-amino acid oxidase (from Trigonopsis variabilis) was used as the DNA template. The effects of flow rate and cross contamination on the efficiency of the PCR device were studied. In addition, the effects of surface modification by BSA, Pluronic® F-68, Pluronic® F-127, and neat silane were discussed.
Yang, Han-Yu y 楊翰宇. "PDMS-based cylindrical hybrid lens for fluorescence enhancement used in microfluidics". Thesis, 2011. http://ndltd.ncl.edu.tw/handle/91557050927847378187.
Texto completo國立交通大學
影像與生醫光電研究所
100
Microfluidic systems have recently been developed and applied for many biological and chemical applications based on fluorescence detections. Because of the tiny amount of sample in the system, the induced fluorescence can be weak. Therefore, most of microfluidic systems require many optical components, such as filters, lens, or micro structure, to enhance the efficiency of fluorescence detection. However, these components encounter the common issues of complex manufacturing processes and expensive costs. In this study, a miniature, cylindrical, and hybrid lens made of polydimethylsiloxane (PDMS) is proposed to focus the excitation light and simultaneously improve the efficiency of collecting fluorescence in the microfluidic device. The hybrid lens integrated a laser focusing lens and a fluorescence collecting lens to achieve the dual functions and simplify the optical setups. Moreover, PDMS has advantages of low-cost and easy fabrication compared with conventional optical components. For the efficiency of focusing excitation light, the proposed hybrid lens can provide an 81.7% reduction of spot size and 93.39% efficiency enhancement of the excitation light. For the integrated efficiency of collecting fluorescence, the proposed hybrid lens can provide 85.00% and 108.42% fluorescence enhancements for Rhodamine 6G and Nile Red respectively.
Peng, Rong-Gui y 彭榮貴. "Design and Performance Analyses of Si and PDMS-based Micro PEMFC". Thesis, 2011. http://ndltd.ncl.edu.tw/handle/26598371384470373619.
Texto completo國立交通大學
機械工程學系
99
The dissertation consists of two parts. Part one utilizes Micro- electromechanical Systems (MEMS) technology to fabricate micro Si-based proton exchange membrane fuel cell (PEMFC) and followed by carrying out a series experiments. It designs masks firstly, then, uses MEMS technology to fabricate the flow field plate. The processes include physical vapor deposition (PVD) and chemical vapor deposition (CVD), coating photo resist (PR), exposure, development, dry and wet etching. Finally, assemble the components, such as acrylic end plates, flow field plates, collector plates, gaskets and gas diffusion layer (GDL) into a cell. The active area of the membrane-electrode-assembly (MEA) is 2cm×2cm. The parameters include open ratio of flow field plates, conducting area of current collector, material of current collector and different cathode gases, respectively. The experimental results show that both the conducting area and material of current collector slices have great influence on the performance of micro PEMFC, especially the former one. The performance is better for open ratio 75% compared with those of 50 and 67%. The concentration polarization is improved by increasing the air flow rate at high current densities. Furthermore, the performance at difference operating voltages can maintain a stable power output for a long time use up to 10 hours. Part two uses dry etching process of MEMS to fabricate micro PDMS-based (Polydimethyl Siloxane) PEMFC. A series of performance experiments on a single micro PDMS PEMFC was carried out firstly. The experimental parameters included current collector shape, convection type and clamping force, respectively. Secondly, a planar PDMS-based PEMFC stack was designed and assembled to test the performance. In this test, the parameters consisted of clamping force and fuel supply condition. In addition, both the single cell and stack were tested for durability. The experimental results showed that both the performances of the air-breathing and forced convection cells increase with an increase of the circle number on the current collector under the same current collector open ratio; The forced convection cell is a better choice for long-time high current-density output, whereas the air-breathing cell is more suitable for lower current density output; An appropriate clamping torque should be considered carefully to enhance the performance but without narrowing down the fuel flow channels; The increase of flow rate is not a best way to improve the concentration loss in this air-breathing stack experiment because of the limiting air supply. Experiments also employed the thermal imager to observe the cell temperature. It was found that each cell in the same stack has different performance under series arrangement; Both the single micro PDMS fuel cell and the cell stack can maintain a stable power output for a long time use up to 14 hours. Finally, a comparison between PDMS-based PEMFC and Si-based one was made. The PDMS-based PEMFC has a better performance than that of the Si-based one under both the forced oxygen supply and air-breathing ways, because PDMS substrate with high thermal insulation can quickly evaporate the liquid water.
Yeh, Yi-hsing y 葉怡杏. "Novel silicon hydrogel based on PDMS-polyurethane-HEMA for contact lens application". Thesis, 2009. http://ndltd.ncl.edu.tw/handle/38194141679201755736.
Texto completo國立臺灣科技大學
高分子系
97
A novel hydrogel based on the block copolymer of polydimethylsiloxane-polyurethane (PDMS-PU) and 2-hydroxyethyl methacrylate (HEMA) was synthesized. This novel hydrogel was consisting of soft segment of poly(dimethylsiloxane) dialkanol with hydroxyethyl propoxy end groups and hard segment of isophorone diisocyanate (IPDI). Poly(ethylene glycol) methacrylate (PEGMA) was added as the chain-extender. Finally, by reacting silicone macromer (PDMS-PU) with HEMA under UV-photopolymerization, the copolymer was resulted (PDMS-PU-HEMA). The results showed that the water content of the hydrogel increased with the HEMA content. The Young’s modulus and tensile strength of the dry hydrogel also increased with HEMA content. At a HEMA content of 40%, the oxygen permeability (Dk) would remain 77% of that of the PDMS-PU. The optical transmittance of the PDMS-PU-HEMA hydrogel remained 94% of that of PDMS-PU. Furthermore, these hydrogels were non-cytotoxic through in vitro L929 fibroblasts assay. Overall results demonstrated that the PDMS-PU-HEMA hydrogel exhibited relatively high oxygen permeability, hydrophilicity, and optical transparency, therefore would be applicable as an ophthalmic material.
Chen, Wei-Hao y 陳偉豪. "Novel Stretchable Ambipolar Electrochromic Devices Based on Highly Transparent Silver Nanowire/PDMS Hybrid Electrodes". Thesis, 2018. http://ndltd.ncl.edu.tw/handle/up97qr.
Texto completo國立臺灣大學
高分子科學與工程學研究所
106
This study has been separated into four chapters. Chapter 1 is the general introduction. Chapter 2 includes the synthesis of silver nanowire (AgNW) with high aspect ratio, preparation of highly transparent AgNW/PDMS hybrid electrodes and the fabrication of the stretchable ambipolar electrochromic devices (ECDs) with five different EC color performance. Chapter 3 describes the stabilities studies of the AgNW/PDMS stretchable ECDs and the ways for improvement. Chapter 4 is conclusions. The synthesis of AgNW, basic characterization, fabrication parameters, optical and electrical properties, electrochemical and spectroelectrochemical properties of the novel stretchable ambipolar ECDs were investigated and improved. The AgNW/PDMS hybrid electrodes were prepared by a simple preparation process. Owning to the carefully controlled experimental conditions, the obtained stretchable electrodes showed great performance on both optical and electrical properties. Moreover, we applied these AgNW/PDMS electrode to fabricate the stretchable ECDs with five different triphenylamine (TPA) EC materials and heptyl viologen. The obtained stretchable ECDs all showed transparent at neutral state and switched to various colors according to the different redox pair under applied potential. In another part, we firstly examined the electrochemical stabilities of the above ambipolar ECDs. There were an improvement on their electrochemical stability while utilizing the ambipolar EC pair with lower redox potential. Besides, we also find out another approach for improvement by covering the exposed AgNW with electroactive EC films. By this sensible combination, we can not only increase the stability of AgNW/PDMS electrode but also get the EC behavior on these stretchable electrode.
Yu-ChiehHsiao y 蕭宇傑. "Cleavable Peptide Synthesis on Polydimethylsiloxane (PDMS)-based Microarrays and Its Application for PKA Kinase Assay". Thesis, 2014. http://ndltd.ncl.edu.tw/handle/45885866078939904334.
Texto completo國立成功大學
化學系
102
Solid state synthesis of cleavable peptides on the surface of gold nanoparticle-coated poly(dimethylsiloxane) (PDMS) substrate was demonstrated as an array format using a 5-mer molecule of poly-Trp5 as an example and heterobifunctional crosslinkers as the anchoring layer, t-Boc chemistry/ trifluoroacetic acid (TFA) for protection and de-protection, and reducing agents for peptide cleavage. The method was judiciously designed to use reagents and solvents that are compatible with the PDMS polymer substrate and the formation of the covalent binding during the synthesis steps were monitored by Infrared spectroscopy (IR), Atomic Force Microscopy (AFM) and Fluorescence spectroscopy. The products of each step were characterized by mass spectrometry and the final production yield of the 5-mers was estimated to be near 43%. Due to flexible molding techniques for PDMS fabrication, such peptide synthesis can be implemented inside a traditional 96-well ELISA plate or on a patterned PDMS substrate for assay developments using either the light or MS detection. We applied the method to fabricate kemptide peptide microarrays on PDMS and demonstrated that protein kinase A (PKA) could phosphorylate the serine residue by chemiluminescence detection.
Cheng, Yu-Hung y 鄭有宏. "Study of flexible organic light emitting diodes for functional lighting by using PDMS-based substrate". Thesis, 2007. http://ndltd.ncl.edu.tw/handle/36297185883545356471.
Texto completo國立清華大學
電機工程學系
96
The requirement for flexible electronics and functional lighting has made the design of low-cost flexible optical devices increasingly important. This study proposes a novel technology for preparing a flexible substrate for OLEDs (organic light emitting diodes), based on mechanical, electrical and optical considerations. PDMS (polydimethylsiloxane) was used as the substrate of OLEDs. Meanwhile, it can be used for a light-emitting-enhancement layer and a package layer for OLEDs. This work can be organized into three main parts. First, the substrate suitable for device fabrication was developed by mixing the PDMS substrate with various nanoparticles, to optimize the CTE (coefficient of thermal expansion) and hardness. Embedding the Al2O3 nanocomposite layer nearer the PDMS surface showed the best improvement on surface hardness. Second, a mesh structure on the emitting surface to enhance the external quantum efficiency and its fabrication process that can be applied for a large-area device with low production cost were developed. This mesh structure can be integrated with the Al2O3-embedded PDMS substrate and the electroluminance of the OLED under mechanical strain was examined. The experimental results indicate that the PDMS-based substrate with the optical structures can be successfully realized for FOLEDs (flexible organic light emitting diodes). However, such FOLEDs still suffer from short lifetime and bending instability due to relatively large CTE. Possible solutions are proposed to make this system more robust in FOLEDs applications.
Cheng, Wei-Chih y 鄭偉志. "Analysis of the Optical Characteristic of Photonic Crystal based on Silicon Substrate with PDMS Pillars". Thesis, 2015. http://ndltd.ncl.edu.tw/handle/y3zwsk.
Texto completo國立虎尾科技大學
光電與材料科技研究所
103
In this thesis, the photonic crystal design software Crystal Wave ver. 3.2 is used to simulate the silicon-based substrate with etched periodically arranged holes, filled with PDMS material. Plane Wave Expansion method is used to calculate the photonic band gap, then the photonic crystal waveguide and resonant cavity is formed by crystal defects. Simulate the propagation behaviors of light using finite-difference time-domain method. Design the structure of waveguides and to compare the filter characteristics in different structures. By the simulation results, we can find out some filter structure could be suitable in optical communication devices.
Hsu, Pei-ning y 徐佩寧. "Fiber-optic Fabry-Pérot Interferometer Based on a PDMS Microlens on a Fiber Tip for Sensing Applications". Thesis, 2015. http://ndltd.ncl.edu.tw/handle/g9fan5.
Texto completo國立中山大學
光電工程學系研究所
103
Fiber-optic Fabry-Pérot interferometers (FFPIs) have been widely utilized in many areas due to their advantages of compact size and high sensitivity. FFPIs have two reflective interfaces. As light propagates to the two interfaces, we can get two reflective light beams with different optical paths to form the interference spectrum. The optical path difference will be influenced by the surrounding environment. As a result, we can use the FFPIs for sensing applications. In previous studies, the FFPIs are fabricated by etching, femtosecond lasers or splicing different types of fibers. However, those fabrication processes are complicated or expensive. In this thesis, we fabricate a FFPI which is based on a Polydimethylsiloxane (PDMS) microlens on a fiber tip. It has simple and low-cost fabrication process. The PDMS microlens can function as the Fabry-Pérot cavity which is flexible and recoverable. We use the PDMS-microlens-based FFPI for sensing applications of temperature, refractive index, displacement, and tilt angle. The temperature sensitivity of the FFPI with the radius of curvature R = 130μm is 631pm/°C between 30°C~65°C. When we vary the surrounding refractive index, the intensity of interference peak will be changed. The refractive index sensitivity of the FFPI with R = 93μm is -59.61dB/RIU in the refractive index range of 1.333~1.3997. The sensitivity of displacement is -50.98nm/μm for the FFPI with R = 103μm, which is better than other displacement sensors. In the tilt angle measurement, when the tilt angle is increased, the extinction ratio is decreased. We have also found that the FFPI with smaller R has a larger critical angle. In addition, the appearances of the PDMS microlens have no change after measurement, which demonstrates that the PDMS microlens has the good recoverable property.
Chen, Yung-Ming y 陳永明. "A novel CNT-PDMS-based pressure and temperature sensor with resistivity retaining and recovering by using dielectrophoresis effect". Thesis, 2011. http://ndltd.ncl.edu.tw/handle/87021663804433081257.
Texto completo國立臺灣大學
機械工程學研究所
99
In this work, we present novel resistive pressure and temperature sensors with reversible signal tracking capabilities. The sensing material was prepared by dispersing multi-walled carbon nanotubes (CNTs) and silver nano-particles through polydimethylsiloxane (PDMS) polymer with the assistance of the dielectrophoresis (DEP) technique. When the sensing element is pressed, a number of conductive CNT networks within the polymer are broken, thereby increasing the resistivity of the element. The polymer retains resistivity following the removal of the external force, and resistivity can be recovered to the original value using DEP to reform the conductive CNT networks. Similar resistivity behaviors induced by temperature elevation and DEP were also observed. This study demonstrates the performance and repeatability of the proposed sensing elements and investigates the characteristics of devices with various electrode gaps. We also fabricated flexible tactile sensor array and demonstrated image retaining and erasing capabilities. The potential applications of the sensor include reusable footstep tracking carpets, inertia switches, temperature switches, and other applications.
Wang, Chih-Ming y 汪志銘. "Low-cost and Flexible Atmospheric-pressure Microplasma Generation Devices as a Microreactor of CO2 Decomposition and Integrated with PDMS-based Microchannels". Thesis, 2015. http://ndltd.ncl.edu.tw/handle/94550348891955820317.
Texto completoPai, Jeng Yung y 鄭永湃. "The Emulsion Polymerization and Physical Properties of EO-ended PDMS-based PUs and their Application of Water Vapor Permeability and Waterproof on Nylon Fabrics". Thesis, 1994. http://ndltd.ncl.edu.tw/handle/69951564735087172272.
Texto completo"Study on Buckling of Stiff Thin Films on Soft Substrates as Functional Materials". Doctoral diss., 2014. http://hdl.handle.net/2286/R.I.24814.
Texto completoDissertation/Thesis
Ph.D. Mechanical Engineering 2014
Wells, Elizabeth Christine. "Fluidic Tuning of a Four-Arm Spiral-Based Frequency Selective Surface". Thesis, 2011. http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9403.
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