Artículos de revistas sobre el tema "Otomycoses"

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1

Zaror, Luis, O. Fischman, F. A. Suzuki y R. G. Felipe. "Otomycosis in São Paulo". Revista do Instituto de Medicina Tropical de São Paulo 33, n.º 3 (junio de 1991): 169–73. http://dx.doi.org/10.1590/s0036-46651991000300001.

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In view of the lack of researches on otomycoses in Brazil, we have tried to study their incidence, their clinical characteristics and the predisponent factors During one year, 22 suspected cases were seen, 20 of them corresponded to otomycosis infections. The most frequent species were Aspergillus niger (35%) and Candida albicans (20%). The genus Aspergillus represented 75% of the isolates. Itching and hyperaemia (70%), otalgia (65%), hipoacusia (50%) were the commonest signs. Lack of cerumen (70%) chronic otitis (30%) previous antibiotic therapy and eczema (25%) were the most outstanding predisponent factors.
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2

Bojanović, Mila, Aleksandra Ignjatović, Marko Stalević, Valentina Arsić-Arsenijević, Marina Ranđelović, Vladimir Gerginić, Zorica Stojanović-Radić, Ognjen Stojković, Emilija Živković-Marinkov y Suzana Otašević. "Clinical Presentations, Cluster Analysis and Laboratory-Based Investigation of Aspergillus Otomycosis—A Single Center Experience". Journal of Fungi 8, n.º 3 (18 de marzo de 2022): 315. http://dx.doi.org/10.3390/jof8030315.

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Species of Aspergillus (A.) niger complex and A. flavus complex are predominant molds that are causative agents of otomycoses. The goal of this study was to investigate the clinical presentation, diagnostic procedure, and appearance of relapse in patients with Aspergillus-otomycosis, as well as to determine the biofilm production ability of species isolated in relapse. Thirty patients with laboratory evidenced Aspergillus-otomycosis followed by two check-ups (30 and 60 days after initiation of treatment with antimycotics for local application) were included in the study. For isolation and identification of Aspergillus spp. the standard mycological procedure was applied. Results showed very high sensitivity of microscopy, but 16.7% Aspergillus species required the optimal temperature of 27–28 °C for cultivation. Applied statistical cluster analysis showed a defined specific cluster/group of patients with A. niger complex-otomycosis. Sixty days after diagnosis and treatment initiation, six patients had a relapse, with the same species of Aspergillus genus being the cause. To establish the ability of biofilm production, the modified method described by Pierce and Kvasničková was performed, and all six species isolated in the relapse episode had the ability to produce biofilm. Official criteria and recommendations are needed due to the possibility of misdiagnosis, which leads to the prolongation and complication of the disease.
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3

&NA;. "Bifonazole for otomycoses - pilot study". Inpharma Weekly &NA;, n.º 925 (febrero de 1994): 14. http://dx.doi.org/10.2165/00128413-199409250-00033.

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4

MUFTIC, Mahmoud Kamal. "Mycostatin in Treatment of Otomycoses". Mycoses 1, n.º 5 (24 de abril de 2009): 156–61. http://dx.doi.org/10.1111/j.1439-0507.1958.tb04015.x.

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5

Bojanović, Mila, Marko Stalević, Valentina Arsić-Arsenijević, Aleksandra Ignjatović, Marina Ranđelović, Milan Golubović, Emilija Živković-Marinkov, Goran Koraćević, Bojana Stamenković y Suzana Otašević. "Etiology, Predisposing Factors, Clinical Features and Diagnostic Procedure of Otomycosis: A Literature Review". Journal of Fungi 9, n.º 6 (13 de junio de 2023): 662. http://dx.doi.org/10.3390/jof9060662.

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Otomycosis (OM) is a superficial fungal infection of the external auditory canal (EAC) with a worldwide prevalence ranging from 9% to 30%. Commonly, otomycoses are caused by Aspergillus (A.) niger complex and Candida spp. Other causative agents are yeasts of the genera Cryptococcus spp., Rhodotorula spp., Geotrichum candidum, dermatophytes (Trichophyton mentagrophytes), and non-dermatophytes molds (Fusarium spp., Penicillium spp., Mucorales fungi). The widest range of different species causing OM are found in the territories of Iran, India, China, Egypt, Mexico, and Brazil. Fungal infection of the EAC varies from mild to severe forms. It can be acute, subacute, or chronic, and is often unilateral, while the bilateral form is more common in immunocompromised patients. From an epidemiological point of view, tropical and subtropical climates are the most significant risk factor for the development of otomycosis. Other predisposing conditions include clothing habits, EAC hygiene practices, long-term antibiotic therapy, diabetes, and immunodeficiency. Since it is often difficult to distinguish otomycosis from an infection of a different origin, laboratory-based evidence, including standard procedures (microscopy and cultivation), is essential for diagnosis. For the treatment of this superficial fungal infection, there are no official therapeutic guidelines and protocols. However, many antifungals for local application, such as polyene, imidazoles, and allylamines, can be applied, as well as systemic antimycotics (triazoles) in severe forms of infection.
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6

Dorko, E., A. Jenča, M. Orenčák, S. Virágová y E. Pilipčinec. "Otomycoses of candidal origin in eastern Slovakia". Folia Microbiologica 49, n.º 5 (septiembre de 2004): 601–4. http://dx.doi.org/10.1007/bf02931541.

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7

Cojocaru, I., I. Alteraş y Lucia Dulǎmiǎ. "Some data on the treatment of otomycoses". Mycoses 13, n.º 5 (24 de abril de 2009): 243–46. http://dx.doi.org/10.1111/j.1439-0507.1970.tb01258.x.

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8

Aboulmakarim, S., H. Tligui, M. El Mrini, I. Zakaria, N. Handour y A. Agoumi. "Otomycoses : étude clinique et mycologique de 70 cas". Journal de Mycologie Médicale 20, n.º 1 (marzo de 2010): 48–52. http://dx.doi.org/10.1016/j.mycmed.2010.01.002.

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9

Merad, Y., H. Adjmi-Hamoudi, T. Lansari y S. Cassaing. "Les otomycoses dermatophytiques : étude rétrospective de 2010 à 2015". Journal de Mycologie Médicale 26, n.º 2 (junio de 2016): e35-e36. http://dx.doi.org/10.1016/j.mycmed.2016.04.078.

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10

Haine-Madani, K., I. Boukerzaza y B. Hamrioui. "Les otomycoses : épidémiologie et diagnostic au CHU Mustapha Bacha d’Alger". Journal de Mycologie Médicale 23, n.º 3 (septiembre de 2013): 210. http://dx.doi.org/10.1016/j.mycmed.2013.07.049.

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11

Morozova, O. V., V. N. Krasnozhen, N. I. Glushko, E. V. Khaldeeva y S. A. Lisovskaya. "The role of mycological culture studies in diagnostics of otomycoses". Vestnik otorinolaringologii 80, n.º 4 (2015): 41. http://dx.doi.org/10.17116/otorino201580441-43.

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12

Nascimento, Brisa Dantas Rodrigues, Naiana Araújo de Oliveira, Letícia Rodrigues Nunes Pinheiro, Jessyca Matos, Isabelle Santos Alves y Renato Oliveira Martins. "Clinical and Mycobiological Profile of Otomycoses in the Amazon, Brazil". International Journal of Health Science 4, n.º 13 (26 de febrero de 2024): 2–7. http://dx.doi.org/10.22533/at.ed.1594132423012.

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13

Marsh, Roger R. y Lawrence W. C. Tom. "Ototoxicity of Antimycotics". Otolaryngology–Head and Neck Surgery 100, n.º 2 (febrero de 1989): 134–36. http://dx.doi.org/10.1177/019459988910000209.

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Neither otomycoses nor defects of the tympanic membrane are rare. In cases of fungal infection when the tympanic membrane is not intact, the possibility exists that antimycotic medication could enter the middle ear and diffuse into the cochlea via the round window. Five antimycotic preparations were tested for acute ototoxic potential in guinea pigs. Those containing acetic acid or propylene glycol caused appreciable elevation of brainstem response thresholds, while little or no impairment resulted from tolnaftate or clotrimazole solutions in polyethylene glycol 400.
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14

Meradji, A., S. Zeroug y A. Touabti. "Les otomycoses : étude épidémiologique et mycologique au CHU Saadna-Abdenour de Sétif". Journal de Mycologie Médicale 24, n.º 3 (septiembre de 2014): e126. http://dx.doi.org/10.1016/j.mycmed.2014.06.039.

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15

Adoubryn, K. D., V. K. N’Gattia, G. C. Kouadio-Yapo, L. Nigué, D. K. Zika y J. Ouhon. "Épidémiologie des otomycoses au centre hospitalier et universitaire de Yopougon (Abidjan-Côte d’Ivoire)". Journal de Mycologie Médicale 24, n.º 2 (junio de 2014): e9-e15. http://dx.doi.org/10.1016/j.mycmed.2013.07.057.

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16

Merad, Yassine, Haiat Adjmi-Hamoudi, Kader Lahmer, Elhadj Saadaoui, Sophie Cassaing y Antoine Berry. "Les otomycoses chez les porteurs d’aides auditives : étude rétrospective de 2010 à 2015". Journal de Mycologie Médicale 26, n.º 1 (marzo de 2016): 71. http://dx.doi.org/10.1016/j.mycmed.2016.02.012.

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17

Iken, Maryem, Hafida Naoui, Laila Boumhil, Zohra Lemkhente y Badre Eddine Lmimouni. "Otomycoses : étude clinique et mycologique de 75 cas diagnostiqués à l’hôpital militaire Mohammed V de Rabat". Journal de Mycologie Médicale 25, n.º 3 (septiembre de 2015): 242–43. http://dx.doi.org/10.1016/j.mycmed.2015.06.061.

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18

Chow, V. T. K., B. Ho, G. S. Hong y T. C. Liu. "Bacterial and mycotic otological infections in Singapore". Journal of Hygiene 97, n.º 2 (octubre de 1986): 385–92. http://dx.doi.org/10.1017/s0022172400065475.

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SummaryThis paper describes a microbiological study of 84 young adult men with clinical otitic infections. Gram-negative aerobic bacilli were frequently isolated from these patients diagnosed as having otitis externa or chronic suppurative otitis media, of which Pseudomonasspecies predominated.Staphylococcus aureus, S. epidermidis and aerobic Corynebacterium species (diphtheroids) were also found. About 40% of ear infections were attributed to otomycoses, chiefly from Aspergillus species and Candida parapsilosis. Antimicrobial susceptibility testing of the bacterial isolates revealed that Pseudomonas species were generally resistant to antibiotics commonly employed in general practice: ampicillin, erythromycin, co-trimoxazole, tetracycline and cephaloridine. However, polymjwin B, gentamicin and neomycin were active against some Pseudomonas isolates. Other Gram-negative bacilli were also mainly sensitiveto gentamicin, neomycin as well as co-trimoxazole. Disc diffusion and minimum inhibitor concentration studies demonstrated good activity of ceftazidime, cefoperazone, tobramycin and carbenicillin against strains of Pseudomonas species and other Gram-negative rods. Cefotaxime and cefoxitin were active against Gram-negative bacilli other than Pseudomonas species. Beta-lactamase production did not appear to be the main mechanism of resistance in these communityacquired Gram-negative bacillary isolates. The antimicrobial therapy of otological infections is reviewed.
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19

Guto, John Abuga, Christine C. Bii y David W. Denning. "Estimated burden of fungal infections in Kenya". Journal of Infection in Developing Countries 10, n.º 08 (31 de agosto de 2016): 777–84. http://dx.doi.org/10.3855/jidc.7614.

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Introduction: Kenya is a developing country with a high rate of tuberculosis (TB) and a moderate HIV infection burden. No estimate of the burden of fungal diseases in Kenya is published. Methodology: We used specific populations at risk and fungal infection frequencies from the literature to estimate national incidence or prevalence of serious fungal infections. Used sources were: 2010 WHO TB statistics, Kenya Acquired Immunodeficiency Syndrome (AIDS) Epidemic Update 2012, Kenya Facts and figures 2012, Kenya Demographic and Health Survey 2008-2009. Results: Of Kenya’s population of ~40 million, 43% are under 15 years old and approximately 594,660 Kenyan women get >4 episodes Candida vulvovaginitis annually (2,988/100,000). The HIV/AIDS population at risk of opportunistic infections (OI) is 480,000 and the OI estimates include 306,000 patients with oral thrush (768/100,000), 114,000 with oesophageal candidiasis (286/100,000), 11,900 with cryptococcal meningitis (29/100,000) and 17,000 patients with Pneumocystis pneumonia (42/100,000). Chronic pulmonary aspergillosis following TB has a prevalence of 10,848 cases (32/100,000). The adult asthma prevalence is 3.1% and assuming 2.5% have allergic bronchopulmonary aspergillosis then 17,696 (44/100,000) are affected. Invasive aspergillosis, candidaemia and Candida peritonitis are probably uncommon. Tinea capitis infects 9.6% of children in Kenya, while fungal keratitis and otomycoses are difficult to estimate. Conclusion: At any one time, about 7% of the Kenyan population suffers from a significant fungal infection, with recurrent vaginitis and tinea capitis accounting for 82% of the infections. These estimates require further epidemiological studies for validation.
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20

MALIK, MUHAMMAD FAHIM, RASHID ZIA y SAJJAD AKRAM. "OTOMYCOSIS". Professional Medical Journal 16, n.º 03 (10 de septiembre de 2009): 419–23. http://dx.doi.org/10.29309/tpmj/2009.16.03.2870.

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b j e c t i v e s : To determine the efficacy of tincture mertheolate in otomycosis. Design: An experimental study. Setting:Department of ENT Allama Iqbal Medical College/ Jinnah Hospital, Lahore. Period: From Dec. 2007 to April 2008. Patients & M e t h o d s A totalof 60 patients of symptomatic otomycosis were investigated prospectively. Aural swabs were collected on first, 7th and 14th day and examined,by direct microscopy of external auditory canal and culture for fungi. Of these 60 patients found to be having pure fungal infection were takenup for mycological and therapeutic study. Results Fungi belonging to Aspergillus were isolated in 57(95%) patients of which Aspergillus nigerwas the commonest isolated in 34(56.6%) patients followed by Aspergillus flavus in 21(35%) and Aspergillus fumigates in 2(3.33). Candidaspecies in 2(3.3%) and Mucor in 1 (1.6%) of patients. The patients were of all age groups but majority were between 21 and 30 years and themale to female ratio was equal. No patient had fungal infection elsewhere in the body. The patients were called for regular follow-up for threeweeks. In 30 cases tincture mertheolate was applied as topical antifungal agent after cleaning the external auditory canal, in 17 patient'sclotrimazole and in rest of the 13 patients miconazole was used. On 7th day, only 8 (13.3%) patients grew fungi in culture. They becamesymptom free on 14th day and no fungal material could be seen on otoscopy, direct microscopy or culture. Tincture mertheolate was found tobe most effective in these patients.
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21

Pulec, Jack L. y Christian Deguine. "Otomycosis". Ear, Nose & Throat Journal 81, n.º 6 (junio de 2002): 370. http://dx.doi.org/10.1177/014556130208100602.

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22

Bakshi, Satvinder Singh y Soumyajit Das. "Otomycosis". Medicina Clínica (English Edition) 155, n.º 10 (noviembre de 2020): 472. http://dx.doi.org/10.1016/j.medcle.2019.08.010.

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23

Bakshi, Satvinder Singh y Soumyajit Das. "Otomycosis". Medicina Clínica 155, n.º 10 (noviembre de 2020): 472. http://dx.doi.org/10.1016/j.medcli.2019.08.003.

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24

Lecanu, J. B., M. Erminy, P. Faulcon y B. Théoleyre. "Otomycose". EMC - Oto-rhino-laryngologie 3, n.º 4 (enero de 2008): 1–8. http://dx.doi.org/10.1016/s0246-0351(08)46827-7.

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25

Kiakojuri, Keyvan, Ramazan Rajabnia, Saeid Mahdavi Omran, Abazar Pournajaf, Mohsen Karami y Mojtaba Taghizadeh Armaki. "Role of Clotrimazole in Prevention of Recurrent Otomycosis". BioMed Research International 2019 (26 de diciembre de 2019): 1–6. http://dx.doi.org/10.1155/2019/5269535.

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Otomycosis is one of the relatively common diseases in the world which is caused by different fungi especially saprophytes. Concerning the relapse of this disease in a number of individuals, the present study was performed to evaluate the inhibitory effect of clotrimazole drop in the relapse of otomycosis. Clinical samples were taken by an ENT specialist from patients suspicious of having otomycosis. A part of these samples were stained, and others were cultured. The diagnosis of otomycosis was made on the basis of the recognizable and characteristic appearance of fungal hyphae or mycelium and fruiting bodies and/or conidiophores under microscopic examination. Patients with suspected otomycosis are not at risk of recurrence after treatment with clotrimazole drops. Out of the 161 individuals in whom definite diagnosis of otomycosis was made, the most affected individuals were, in the age range of 40–49 years, women, urban citizens, and housewives. Pruritus and diminished hearing were the main complaints of the patients. Aspergillus niger and A. flavus as well as Candida albicans were the main causes of the disease. The relapse of disease was observed in only five patients (3.1%), where A. niger was the main fungus. Most relapses were observed in women and in those with diminished hearing, manipulating the ears, ulcers in the canal, and tympanum. Our results suggested that usage of clotrimazole can be effective in reducing the relapse of otomycosis, and concerning the high cost of treating otomycosis while the low cost of using clotrimazole, usage of this drop is recommended to reduce the relapse of otomycosis.
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26

Prasad, Sampath Chandra, Subbannayya Kotigadde, Manisha Shekhar, Nikhil Dinaker Thada, Prashanth Prabhu, Tina D’ Souza y Kishore Chandra Prasad. "Primary Otomycosis in the Indian Subcontinent: Predisposing Factors, Microbiology, and Classification". International Journal of Microbiology 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/636493.

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Objective. To define otomycosis and determine the predisposing factors and microbiology in primary otomycosis.Study Design. Prospective study of two years and review of the literature.Setting. Academic Department of Otolaryngology in a coastal city in India.Patients. 150 immunocompetent individuals of whom 100 consecutive patients with a clinical diagnosis of otomycosis are considered as the study group and 50 consecutive patients with no otomycosis are considered as the control group.Results and Observations. Instillation of coconut oil (42%), use of topical antibiotic eardrops (20%), and compulsive cleaning of external ear with hard objects (32%) appeared to be the main predisposing factors in otomycosis. Aspergilli were the most common isolates (80%) followed byPenicillium(8%),Candida albicans(4%),Rhizopus(1%), andChrysosporium(1%), the last being reported for the first time in otomycosis. Among aspergilli,A. nigercomplex (38%) was the most common followed byA. fumigatuscomplex (27%) andA. flavuscomplex (15%). Bacterial isolates associated with fungi in otomycosis wereS. aureus,P. aeruginosa, andProteusspp. In 42% of healthy external ears fungi were isolated.Conclusion.Aspergillusspp. were the most common fungi isolated, followed byPenicillium. Otomycotic ears are often associated with bacterial isolates when compared to normal ears. Fungi are also present in a significant number of healthy external auditory canals and their profiles match those in cases of otomycosis. The use of terms “primary” and “secondary” otomycosis is important to standardize reporting.
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27

Suresh, Sunethra, Suraj Suresh y Sudha Sivasamy. "Prevalence of otomycosis in patients with cerumen impaction due to ear-phone usage during COVID-19". Indonesian Journal of Medical Sciences and Public Health 2, n.º 1 (30 de octubre de 2021): 28–39. http://dx.doi.org/10.11594/ijmp.02.01.04.

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Background: Otomycosis affects about 9% of patients with otitis externa. One of the predisposing factor is impacted cerumen. Earphone usage causes cerumen impaction. In the light of the recent COVID-19 pandemic, people are housebound due to prolonged lockdown. Hence people are more technology dependent as working from home and studying online has become the norm. Therefore, usage of earphones has proportionately increased, and the impacted cerumen cases have increased. Methods: This cross-sectional study aimed to analyze data from questionnaire to assess the prevalence of otomycosis among patients with impacted cerumen due to excessive earphone usage, establish associations between otomycosis and symptoms such as pain and hearing loss as well as the correlation between fungal growth and the long hours of earphones usage. The relationship between the age of participants and the usage of earphones during the pandemic was also explored. The data was collected from 100 individuals aged 14 to 51 years who sought treatment for symptomatic impacted wax at an ENT clinic in Malaysia. Results: The mean age of participants was 25.9 years. There was a 31% prevalence of otomycosis among these patients. Otalgia was present in 60% of patients with otomycosis (t value 2.94, coefficient 0.27). Approximately 37% of patients had a large air-bone gap indicating conductive hearing loss. There was an insignificant correlation between otomycosis and the longer hours of earphones usage (t value 1.51, coefficient 0.00015). No correlation was found between age of participants and the total hours of earphone usage (t value 0.63, coefficient 0.0012). Conclusion: This study offers initial evidence that earphone usage could be a predisposing factor in developing otomycosis. However, there was no evidence of longer hours of earphones usage increasing the chances of developing otomycosis. Additionally, symptoms like otalgia and conductive hearing loss could be present in both earwax impaction and otomycosis.
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28

Yang, Chunhui. "Tympanic membrane perforation, otitis media and labyrinthitis caused by otomycosis confirmed by intravenous gadolinium 1.5 tesla MRI-a case report". MOJ Clinical & Medical Case Reports 11, n.º 1 (2021): 1–3. http://dx.doi.org/10.15406/mojcr.2021.11.00369.

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Otomycosis is a fungal ear infection, mostly a superficial mycotic infection of the outer ear canal. The infection may be either subacute or acute but chronic form is around 10%. The characteristic of otomycosis are discharge, pruritus, or more severe discomfort. Here we report a 46-year-old Asian woman presented with vertigo and was diagnosed as otomycosis with the complications of tympanic membrane perforation, otitis media and labyrinthitis of inner ear which was confirmed by IV-Gd 1.5 T MRI. This case is a chronic otomycosis related to cerumen removal two year before this onset. Our study supported the suggestion that otomycosis should include fungal infections of the middle and inner ear, furthermore the infection of the inner ear may be included as labyrinthitis with the symptom of vertigo.
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29

Nipa, KK, AHM Kamal y A. Imtiaj. "Prevalence and Clinicomycological studies of Otomycosis: A review". Journal of Bio-Science 28 (28 de diciembre de 2019): 121–35. http://dx.doi.org/10.3329/jbs.v28i0.44718.

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Otomycosis is a chronic ear disease of external auditory canal and it is more prevalent in warm, humid and dusty environment, although it is now found throughout the world. The most commonly found causative agents as of fungal species are Aspergillus and Candida along with preponderance of various fungal and bacterial species has also been reported. The aim of this review is to focus on the prevalence of causal agents of otomycosis in the global context and its clinical management. A total of 63 research articles have been reviewed, which deals prevalence of otomycosis. Its clinicomycological studies both separately and altogether with folk medicine in relation to treatment of otomycosis were also reviewed. Findings of various reports revealed that the Aspergillus and Candida species are the main causal agents of otomycosis. But many reports indicate that a few of other fungal species along with bacteria particularly Staplylococcus aureus and Pseudomonas aeruginosa are also responsible for accelerating this disease in human all over the world. In many reports, improper self-cleaning of ear has been found as major predisposing factor of otomycosis. This review suggests that health education, improvement of socioeconomic status and health caring facilities should be increased for reducing prevalence of otomycosis. However, more research needs to be carried out because of its severe parallel effects to the human health. J. bio-sci. 28: 121-135, 2020
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30

Pandey, Bhuwan Raj, Madan Mohan Singh y Kishor Bajracharya. "Otomycosis and its Predisposing Factors in Out-Patient Department of Otorhinolaryngology in a Tertiary Care Center". Journal of Lumbini Medical College 7, n.º 2 (29 de diciembre de 2019): 76–80. http://dx.doi.org/10.22502/jlmc.v7i2.291.

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Introduction: Otomycosis is a fungal infection of external auditory canal frequently encountered by otorhinolaryngologists. It causes discomfort to patients with varied symptoms of pruritus, otorrhea, aural fullness and earache. People with a habit of using unnecessary ear drops, cleaning ear with unsterilized objects and those who use mustard oil are all prone to otomycosis. This study aims to find out the association between otomycosis and its predisposing factors. Methods: This study was undertaken in the Department of Otorhinolaryngology of a tertiary hospital from March 2018 to February 2019 and a total of 300 clinically diagnosed cases of otomycosis were enrolled for the study. Results: The mean age ±SD of the patients was 37.7 ± 18.8 years. Females (n=172, 57.3%) were more prone to otomycosis than males (n=128, 42.7%). The most common presenting symptom was pruritus only (n=95, 31.7%) with unilateral involvement being more common. The most common predisposing factor was mustard oil instillation (n=124, 41.3%). Aspergillus niger was the most common fungus causing otomycosis in this study (n=104, 34.7%). Positive fungal cultures were observed in 285 specimens (95%). The fungal growth (n=285) was high in patients with the history of instilling mustard oil (42.8%) into the ear, 34.0% in topical steroid containing ear drops and 23.2% in self-cleaning group. Conclusion: Otomycosis is common in people using unnecessary steroid containing ear drops, cleaning ear with unsterilized objects and instillation of mustard oil.
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31

Khasanov, Ulugbek S. "FEATURES OF MYCOLOGICAL AND CLINICAL STUDIES OF OTOMYCOSIS". American Journal of Medical Sciences and Pharmaceutical Research 03, n.º 01 (1 de enero de 2022): 40–59. http://dx.doi.org/10.37547/tajmspr/volume04issue01-06.

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The results of our studies made it possible to determine the main pathogenetic factors in the development of otomycosis in the examined patients, which is especially important; since fungi - causative agents of otomycosis are conditionally pathogenic microorganisms and show their pathogenic properties only under certain conditions. We found that an important factor for the development of otomycosis is the presence of general somatic diseases, which, according to the present study, were present in the majority (70.1%) of patients, which indicates a decrease in the body's resistance to opportunistic flora against the background of chronic diseases, various metabolic disorders. 25.7% of patients had diseases of the gastrointestinal tract, in which dysbiosis develops with a decrease in the proportion of obligate microflora, a decrease in natural resistance to fungal flora. Diseases of the cardiovascular system of varying severity, including myocardial infarction, were found in 23.45% of patients. The fact that in 32 patients otomycosis developed against the background of diabetes mellitus testifies in favor of the pathogenetic significance of carbohydrate metabolism disorders in the development of mycosis. A small number of observations and the results obtained did not allow us to state with certainty that there is a direct relationship between the incidence of otomycosis and antibiotic therapy. Analysis of our clinical material showed that prior to the diagnosis of otomycosis, systemic antibiotic therapy according to the anamnesis was carried out in 20 patients, local - in 9 patients (a total of 29 patients - 7.1% of the number of patients with otomycosis). We found that traumatic factors in the form of a systematic toilet of the ear canal with a cotton swab, removal of sulfuric plug, use of endoural headphones play an important role in the development of fungal ear infections. Against the background of trauma, otomycosis developed in 56.5% of patients.
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Arsovic, N. A., A. V. Banko, M. V. Dimitrijevic, V. Z. Djordjevic, J. P. Milovanovic y V. A. Arsenijevic. "Protease activities of Candida spp. isolated from otitis externa: Preliminary result". Acta chirurgica Iugoslavica 56, n.º 3 (2009): 113–16. http://dx.doi.org/10.2298/aci0903113a.

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Otomycosis is a fungal infection of the ear predominantly caused by Candida and Aspergillus spp. The possible virulence factors of Candida spp. are enzymes, such as proteases, phospholipases, phosphatases and esterase. According to our knowledge, protease production in Candida strains isolated from patients with otomycosis has not been investigated. The present study was aimed at determining in vitro protease activity in 8 strains of Candida spp. (C. parapsilosis, C. famata, C. guilliermondii and C. albicans) isolated from children with otomycosis. A majority of isolated strains 7/8 (87.5%) were protease positive. The protease activity ranged from Pz 0.61 to 0.78. Further investigation is necessary to clarify the contribution of protease production to Candida virulence associated with otomycosis.
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Arsenijevic-Arsic, Valentina, Nenad Arsovic, Aleksandar Dzamic, Andreja Trpkovic, Ivana Zec-Kranjcic y Vojko Djukic. "Protease activities of Candida spp. isolated from immunocompetent patients with otomycosis". Jugoslovenska medicinska biohemija 23, n.º 2 (2004): 171–74. http://dx.doi.org/10.2298/jmh0402171a.

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Otomycosis is a fungal infection of the ear dominantly caused by Candida and Aspergillus spp. The possible virulence factors of Candida spp. are enzymes, such as proteases, phospholipases, phosphatases and esterase. Protease production in Candida strains isolated from patients with otomycosis is, according to our knowledge, not investigated. The present study was aimed at determining in vitro protease activity in 28 strains of Candida spp. (C. parapsilosis, C. famata, C. guilliermondii, C. albicans and C. kefyr) isolated from patients with otomycosis. The majority of isolated strains 25/28 (89.28%) were protease positive. The protease Pz ranged from 0.691 to 0.851. The futher investigation is necessary to clarify contribution of protease production to Candida virulence associated with otomycosis.
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Victoria, Dinda, Anriani Puspita Karunia Ning Widhi y Darmawan Anton Budhi. "PREVALENCE OF (Aspergillus niger) IN OTOMYCOSIS AT PROF. DR. MARGONO SOEKARJO HOSPITAL". Mandala Of Health 16, n.º 1 (29 de marzo de 2023): 01. http://dx.doi.org/10.20884/1.mandala.2023.16.1.8005.

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Otomycosis is a chronic fungal infection with high prevalence. Environmental factors dan predisposing factors can influence a patient’s vulnerability to otomycosis. According to studies conducted in several country, Aspergillus niger is the common fungus that causes otomycosis. This study aims to determine the prevalence of Aspergillus niger in patients at Prof. dr. Margono Soekarjo Hospital, who was clinically diagnosed with otomycosis. The study was done at the ENT Poly of Prof. dr. Margono Soekarjo Hospital and Microbiology Laboratory of Medicine Faculty, Jenderal Soedirman University between August 2022 to Januari 2023 as a descriptive observational study. According to the inclusion criteria, there were 42 subjects and 46 samples that ENT specialists carried out with sterile flocked swabs, the isolated the samples bedside on SDA Chloramphenicol, Czapek Dox agar, and object glass. Samples were observed macroscopically and microscopically with 10% KOH and LPCB staining. Patients with Aspergillus niger infection in otomycosis at Prof. dr. Margono Soekarjo Hospital , are represented by nine (19,56%) out of the 46 samples. The gender with the highest sex precentage is female (55,56%), folllowed by the age range of 26 – 35 years (44,45%). The prevalence of Aspergillus niger as a cause of otomycosis in Prof. dr. Margono Soekarjo Hospital is 19,56%, the most in females and the age group 26 – 35 years.
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Pak, Martin Wai, Gordon Soo y Charles Andrew van Hasselt. "Flourishing Otomycosis". Ear, Nose & Throat Journal 76, n.º 1 (enero de 1997): 10. http://dx.doi.org/10.1177/014556139707600102.

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Westby, D., N. O'Connell, J. Powell y J. E. Fenton. "The changing nature of paediatric otomycosis in the mid-west of Ireland". Journal of Laryngology & Otology 134, n.º 7 (julio de 2020): 592–96. http://dx.doi.org/10.1017/s0022215120001164.

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AbstractBackgroundFungal otitis externa is prevalent in tropical and sub-tropical climates; however, over the past two decades, there has been a reported increase in the prevalence of otomycosis in paediatric patients from more temperate climates. This study aimed to review the children diagnosed with otomycosis at the University Hospital Limerick with reference to frequency, causative organism, predisposing factors and management.MethodsA retrospective review was conducted of paediatric patients from 2001 to 2015. Patients with positive fungal ear swabs and a diagnosis of otomycosis were identified.ResultsNinety-three patients were positive for candida (mean age, 5.8 years), 10 patients were positive for aspergillus (mean age, 9.1 years) and 1 patient had mixed fungal infection containing both fungi. There was a positive correlation between a diagnosis of otomycosis and prior treatment with topical fluoroquinolones (r = 0.8; p < 0.01).ConclusionThe incidence of otomycosis has been increasing since 2001, which correlates with an increase in the use of topical fluoroquinolones. Previous studies identify aspergillus as the commonest causative fungi; however, this study found that candida was the commonest isolated fungi in the paediatric population.
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Delta, Bimbi Angrayuni. "Antifungal Effect of Aloe Vera Extract on Otomycosis: A Review". Eureka Herba Indonesia 3, n.º 2 (26 de agosto de 2021): 159–63. http://dx.doi.org/10.37275/ehi.v3i2.49.

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Otomycosis is a common disease that can cause a variety of complications, including involvement of the inner ear and, in rare cases, death. Otomycosis management can be difficult and requires close monitoring. There is currently no standardized treatment regimen for otomycosis, which opens up new treatment options such as the use of herbal medicine. Aloe barbadensis miller, also known as Aloe vera, is one of over 400 Aloe vera species and a member of the Liliaceae family. Several studies have shown that Aloe vera extract has antifungal properties. The purpose of this literature review is to identify the components of Aloe vera as well as the mechanism of action in the treatment of otomycosis. The articles chosen were all published in PubMed within the last six years. The review included 7 articles that were obtained.
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38

Pradhan, Bibhu, Nhuchhe Ratna Tuladhar y Ramchaya Man Amatya. "Prevalence of Otomycosis in Outpatient Department of Otolaryngology in Tribhuvan University Teaching Hospital, Kathmandu, Nepal". Annals of Otology, Rhinology & Laryngology 112, n.º 4 (abril de 2003): 384–87. http://dx.doi.org/10.1177/000348940311200416.

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Otomycosis is a not-uncommon clinical problem encountered in our otolaryngology practice. We report 100 diagnoses (107 ears) of otomycosis, of which, on microbiological examination, 87 specimens (81.3%) showed positive fungal cultures. Of these, a single isolate was found in 85 cases (79.4%), mixed isolates were found in 2 cases, and 20 cases (18.7%) had no growth. The most common fungal pathogen found was Aspergillus, followed by Candida albicans. The causative factors for otomycosis were examined. The results of treatment with clotrimazole were analyzed.
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Philip, Ajay, Regi Thomas, Anand Job, V. Rajan Sundaresan, Shalini Anandan y Rita Ruby Albert. "Effectiveness of 7.5 Percent Povidone Iodine in Comparison to 1 Percent Clotrimazole with Lignocaine in the Treatment of Otomycosis". ISRN Otolaryngology 2013 (25 de julio de 2013): 1–8. http://dx.doi.org/10.1155/2013/239730.

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Objectives. Otomycosis is a common ENT disease frequenting the tropics. Its recurrent nature poses a great challenge to the treating physician. In spite of a number of antifungals in the market, the frequent nature of this disease warrants repeated use of these drugs, contributing to drug resistance and financial burden on the rural population. Our primary aims were to evaluate the effectiveness of povidone iodine in the treatment of otomycosis and to identify the most common fungal isolate in our population. Study Design and Setting. A single blinded prospective longitudinal study was done over a period of 12 months in a tertiary referral center. 34 patients in the age group 15–70 years clinically diagnosed with otomycosis were included in this study. These individuals were divided into two groups selected randomly. One arm received 7.5% povidone iodine otic drops and the other 1% Clotrimazole and lignocaine drops. Evaluation was based on resolution of symptoms and signs after treatment. Result. Both arms showed improvements which were comparable thus suggesting the role of povidone iodine in the management of otomycosis. Conclusion. Povidone iodine is an effective antifungal in the treatment of otomycosis.
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Kannan I, Thenmozhivalli PR, Paul Sony y Savetha P. "Study of Etiological Factors, Mycological Profile and Treatment Outcome of Otomycosis". Journal of Advanced Zoology 44, n.º 4 (25 de noviembre de 2023): 663–68. http://dx.doi.org/10.17762/jaz.v44i4.2138.

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Otomycosis is a common condition encountered in ENT practice. Though it is not a serious condition it causes a lot of misery to the patient. Though there are many studies on various aspects about this disease, there are not many studies from this part of the country. Materials and Methods: 75 patients attending ENT OPD and diagnosed to have otomycosis were included in the study. Two aural swabs or whenever possible otomycotic debris scooped out using Jobson –Horne probe was obtained. From one swab, wet mount preparation in 10% KOH (potassium hydroxide) solution and smear for Grams stain were prepared. The second swab / otomycotic debris was directly inoculated into SDA (sabourad’s dextrose agar) medium. Results: Mycological analysis of the swab from external auditory canal has shown that Aspergillus species was the most common fungus isolated followed by Candida species. All patients were treated with regular suction clearance and 1% clotrimazole ear drops. Conclusion: Simple measures like avoiding usage of ear buds/ unsterile material will help in prevention of otomycosis. 1% clotrimazole is effective in achieving complete mycological cure in otomycosis. Regular long term follow-up is required to effectively treat otomycosis.
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41

Boncalon, Rhoda Mae V., Marida Arend V. Arugay y Rachel Zita H. Ramos. "A Preliminary Study on the Efficacy of Plumeria acuminata (Kalachuchi) Bark Extract Ointment versus Clotrimazole Cream in the Treatment of Otomycosis". Philippine Journal of Otolaryngology-Head and Neck Surgery 24, n.º 1 (15 de junio de 2009): 5–8. http://dx.doi.org/10.32412/pjohns.v24i1.701.

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Objective: To compare the therapeutic efficacy of kalachuchi (Plumeria acuminata Ait.) bark extract ointment (KO) and clotrimazole cream 1% (CC) in the treatment of otomycosis. Methods: Design: Randomized double blind controlled trial Setting: Outpatient otorhinolaryngology clinic of a tertiary private hospital Subjects: Patients aged 18-years-old and above diagnosed clinically to have otomycosis with a positive potassium hydroxide (KOH) smear were randomly assigned to kalachuchi (Plumeria acuminata Ait.) bark extract ointment or clotrimazole cream 1% in unlabeled containers. Self-application thrice daily for two weeks followed initial detailed instructions and demonstration. Symptoms, physical findings and repeat KOH smears were recorded after the first and second weeks of treatment. Results: Eighteen patients with otomycosis were enrolled in the study. There was one dropout per treatment group with no intention to treat. There were no statistically significant differences between KO and CC, with 75% (n=8) and 87.5% (n=8) cure rates, respectively. One subject in the KO arm reported severe ear pain. Conclusion: Kalachuchi extract ointment may be a promising topical antifungal agent. Multicenter clinical trials to establish its efficacy and safety as an effective alternative in the management of otomycosis should be conducted. Key words: Otomycosis, kalachuchi, Plumeria acuminata Ait., clotrimazole, clinical trial, herbal medicine
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Wakeel, Nasir, Aasma Tariq, Iqra Gul y Wajahat Hussain. "Prevalence of Otomycosis: An Evaluation among Patients Visiting ENT Clinics". Pakistan Journal of Medical and Health Sciences 15, n.º 10 (30 de octubre de 2021): 2578–79. http://dx.doi.org/10.53350/pjmhs2115102578.

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Aim: To look at the relative frequency and prevalence of the otomycosis in individuals visited ENT department of Bahawal Victoria hospital, Bahawalpur. Methodology: It was a cross-sectional study conducted at ENT department of Bahawal Victoria Hospital, Bahawalpur during 2019-2020. Forty-Two individuals (27 males and 15 females) with a diagnosis of otomycosis on clinical basis were mycologically investigated. To diagnose the condition, ear samples were taken and immediately examined using 10% KOH, followed by culture on Saburo dextrose agar plus Saburo dextrose agar also having chloramphenicol. Different laboratory approaches and differential testing were utilized to determine the kind of fungal species. Ethical approval was taken from Ethical review board of Bahawal Victoria Hospital, Bahawalpur. SPSS version 25 was used for data analysis. Results: Only 42 individuals (66.6%) were identified with otomycosis in this research based on laboratory data, out of 63 people undergoing a clinical diagnosis of otomycosis There were 27 male participants (42.8%) and 15 female participants (23.8%) among them. Penicillium, Aspergillus glaucous, Aspergillus fumigates, Candida albicans and Aspergillus niger have 1 (1.5%), 3 (4.7%), 3 (4.7%), 9 (14.6%) and 26 (41.2%) cases respectively. Conclusion: The most prevalent fungus identified was Aspergillus and Candida species. Key Words: Otomycosis, Aspergillus niger, Candida albicans
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43

Ozcan, K. Murat, Muge Ozcan, Aydin Karaarslan y Filiz Karaarslan. "Otomycosis in Turkey: predisposing factors, aetiology and therapy". Journal of Laryngology & Otology 117, n.º 1 (enero de 2003): 39–42. http://dx.doi.org/10.1258/002221503321046621.

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Otomycosis usually requires long-term treatment and tends to recur. This study was performed on 87 patients with the clinical diagnosis of otomycosis and 20 controls in order to determine the pathogenic agents, predisposing factors and a cost-effective treatment. The predisposing factors included wearing head clothes (74.7 per cent), presence of dermatomycoses (34.5 per cent) and swimming (27.6 per cent). The most common pathogenic fungus was Aspergillus niger (44.8 per cent) in the otomycosis group. The only isolate was Candida albicans in the control group (2.5 per cent). We concluded that administration of four per cent boric acid solution in alcohol and frequent suction cleaning of the ear canal might be a cost-effective treatment for otomycosis since 77 per cent of the patients were treated effectively this way. Eighty per cent of the resistant cases had mixed fungal-bacterial infections, and 50 per cent of them had dermatomycoses. These resistant cases were treated by administration of tioconazole ointment.
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44

Yabo, Umar Sufiyanu, Iseh Kufre Robert, Yahaya Muhammad y Abubakar Musa Giro. "Otomycosis in Patients Attending a Tertiary Health-care Institution in Sokoto, Northwestern Nigeria". Indian Journal of Otology 30, n.º 2 (abril de 2024): 86–89. http://dx.doi.org/10.4103/indianjotol.indianjotol_130_23.

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Introduction: Otomycosis is a superficial fungal infection of the external auditory canal (EAC). The hot, humid, and dusty environment of the tropics and subtropics makes otomycosis more prevalent in these regions. It can be acute or chronic, and usually manifest by aural pruritus, aural fullness, otalgia, otorrhea, tinnitus, and hearing loss. Aim/Objective: The aim of this study was to determine the prevalence and pattern of etiological agents of otomycosis in Sokoto, Northwestern Nigeria. Materials and Methods: This study was a cross-sectional tertiary hospital-based study. One hundred patients with symptoms of otomycosis were recruited from the ENT outpatient clinic of UDUTH Sokoto. Swabs from the ears were taken and evaluated for fungal agents, sociodemographic factors, symptomatology, and risk factors were analyzed. Data analysis was performed with IBM-SPSS 25.0. Results: The patient’s age range of 4–57 years (mean of 18.78 ± 10.67) years, with a male-to-female ratio of 1:1.1; about 124 ear exudates were analyzed, in 75 (60.5%) of ear discharge, 7 different varieties of fungi were isolated, while in 49 (39.5%), there was no fungal growth on culture. The etiological agents found in our study were Aspergillus niger 30 (40.0%) was the most commonly isolated fungi in this study, followed by Candida albicans 25 (33.3%), Aspergillus fumigatus 5 (6.7%), Mucor 5 (6.7%), Penicillium 4 (5.3%), Aspergillus flavus 3 (4.0%), and Rhizopus 3 (4.0%) with A. niger as the most predominant. Conclusion: Otomycosis affects all age groups and both sexes, could be asymptomatic and if left untreated may result to morbidity. Mycological studies should be carried out on all patients with symptoms Otomycosis, this guide to proper management of the disease.
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Viswanatha, Borlingegowda, Dadarao Sumatha y Maliyappanahalli Siddappa Vijayashree. "Otomycosis in Immunocompetent and Immunocompromised Patients: Comparative Study and Literature Review". Ear, Nose & Throat Journal 91, n.º 3 (marzo de 2012): 114–21. http://dx.doi.org/10.1177/014556131209100308.

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A comparative clinical study was carried out that included 50 cases of otomycosis in immunocompetent patients and 50 cases of otomycosis in immunocompromised patients. Clinical presentation, predisposing factors, mycologic profile, and treatment outcomes were compared. Aspergillus spp were the most commonly isolated fungi in the immunocompetent group, and Candida albicans in the immunocompromised group. Bilateral involvement was more common in the immunocompromised group. All the patients were treated with topical clotrimazole ear drops. Four patients in the immunocompromised group did not respond to treatment with clotrimazole but were treated successfully with fluconazole ear drops. Three patients had a small tympanic membrane perforation due to otomycosis.
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Yang, Ting-Hua y Yi-Ho Young. "Eradicating Otomycosis with Terbinafine Solution: Basic and Clinical Investigation". Audiology and Neurotology 24, n.º 4 (2019): 183–90. http://dx.doi.org/10.1159/000501540.

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Background: Otomycosis still remains intractable in clinical practice, likely because topical antifungal agents lack efficacy or are potentially toxic to the inner ear end organs. Objectives: The aim of this study was to investigate whether terbinafine solution is a potential candidate for treating intractable otomycosis in humans. In addition, the toxic effect on the inner ear was also assessed by animal models treated with terbinafine. Methods: Guinea pigs were instilled with 0.1 mL terbinafine (10 and 25 mg/mL) in the left round window membrane. At 2 weeks after treatment, all animals underwent an inner ear test battery and were then sacrificed for morphological study. Clinically, 20 patients with otomycosis were treated with terbinafine solution at a dosage of 0.4 mg. Results: All terbinafine-treated animals showed intact inner ear function when total dosage of terbinafine was <2.5 mg, which was further confirmed by morphological study. Subsidence of otomycosis was achieved in all 20 patients 1 week after treatment with terbinafine (0.4 mg) without untoward effect. No evidence of recurrence was noted 1 year after treatment. Conclusion: The paucity of inner ear toxicity of terbinafine even at a dosage of 2.5 mg was identified in guinea pig models morphologically and physiologically. Topical application of terbinafine solution at a dosage of 0.4 mg may be a potential treatment for otomycosis in humans.
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Lekha, V. Sneha, Neelima Priyadarshini, Siva Subba Rao Pakanati y K. Dilip Kumar. "Mycology of otomycosis and the role of antifungal drops versus antifungal cream in the treatment of otomycosis: an observational study". International Journal of Otorhinolaryngology and Head and Neck Surgery 7, n.º 8 (23 de julio de 2021): 1343. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20212784.

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<p><strong>Background:</strong> Aim of the study was to determine most common mode of presentation, spectrum of fungi involved in otomycosis and to compare the treatment efficacy of 1% clotrimazole drops with 1% clotrimazole cream in management of otomycosis.</p><p><strong>Methods: </strong>A prospective observational study was conducted over a study period of 18 months, in which a total of 60 patients who are clinically diagnosed with otomycosis were included. All the specimens collected from patients were subjected to standard microbiological procedures for identification of fungi involved in otomycosis. Then patients were randomly allotted into 2 groups for treatment with 1% clotrimazole drops or with cream. Improvement in symptoms of pain, pruritis, blocked sensation, and discharge on one-and two-weeks follow-up was recorded. External auditory canal was evaluated for improvement in otomycotic debris. All patients were asked the opinion about preferred modality of treatment.</p><p><strong>Results: </strong>In our study, <em>Aspergillus niger</em> 27(45%) was the predominant species isolated. When compared to the symptoms on day 01 at day 07, significant difference was noted for the improvement of the symptoms and also for the otomycotic debris in both the groups. The group with cream had significantly more blocked sensation. On second week follow up, significant improvement was noted for all the symptoms and otomycotic debris. Forty five out of sixty patients preferred using cream.</p><p><strong>Conclusions:</strong> In our study, <em>Aspergillus </em>species was found to be the commonest fungi involved in otomycosis. 1% topical clotrimazole drops and cream were equally effective in management of otomycosis.</p>
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Ho, Hsu-Chueh, Shih-Hsuan Hsiao, Cheng-Yung Lee y Chen-Chi Tsai. "Treatment of refractory Aspergillus otomycosis with voriconazole: case series and review". Journal of Laryngology & Otology 128, n.º 6 (junio de 2014): 547–51. http://dx.doi.org/10.1017/s0022215114001273.

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AbstractBackground:Voriconazole is a broad-spectrum azole exhibiting strong anti-Aspergillus activity and good long-term tolerance. However, the evidence for voriconazole efficacy against refractory Aspergillus otomycosis is weak.Method:We reviewed the medical records of patients with Aspergillus otomycosis treated with voriconazole from January 2008 to June 2012 in a Taiwanese regional hospital. Demographic data and information regarding underlying diseases, clinical features, treatment and outcome were assessed.Results:In total, 14 cases of Aspergillus otomycosis were treated with voriconazole, including 5 patients with Aspergillus invasive otitis externa. All patients had failed to respond to local treatment, antibiotics or topical agents. One case was lost to follow up. The symptoms of two patients recurred after voriconazole treatment: one patient received a second 12-week course of voriconazole and was cured; and symptoms of the other patient recurred after a second 12-week course of voriconazole, leading to surgical debridement. The remaining 11 patients were cured by voriconazole treatment without extensive surgical debridement.Conclusion:This study demonstrates that voriconazole can be a very effective and convenient therapeutic option for the management of refractory Aspergillus otomycosis.
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Sumbria, Deepshikha, Aamir Yousuf y Rauf Ahmad. "Hospital based study on etiopathogenesis and treatment of otomycosis: ethnic Kashmiri population". International Journal of Otorhinolaryngology and Head and Neck Surgery 5, n.º 5 (27 de agosto de 2019): 1190. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20193651.

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<p class="abstract"><strong>Background:</strong> Otomycosis is the fungal infection of the external ear with bothersome symptoms. The target of the study was to verify the frequency and identification of fungi responsible for the otomycosis and to give the most appropriate treatment. The aims and objectives of the study was to study clinical profile, causative fungal organisms of otomycosis, detect in vitro efficacy of various antifungal solutions against the fungi detected and to establish clinical efficacy of various topical antimycotic solutions in otomycosis in Kashmir.</p><p class="abstract"><strong>Methods:</strong> This study was conducted in the Department of ENT, GMC, Srinagar from February 2014 to July 2015. 152 clinically suspected otomycosis patients were subjected to mycological tests including Gram staining, 10% KOH staining, GTT, SDA and CBL stain to identify the organism. Clotrimazole, terbinafine, lulliconazole, sertaconazole and combination of 1% clotrimazole, chloremphenicol, beclomethasone were given randomly in equal number of these patients. Patients were followed for 4 weeks and results of different antifungals were evaluated clinically. </p><p class="abstract"><strong>Results:</strong> Out of 152 patients 61.8% were females and most of the patients belonged to age group of 25-34 yrs.Most of the patients reported in summer season. Otalgia and itching was the most common symptom. <em>Aspergillus</em> was the most common species identified whereas <em>Candida albicans</em> was the most common individual organism isolated. Lulliconazole was most effective drug whereas combination of 1% clotrimazole, chloremphenicol, beclomethasone was least effective.</p><p class="abstract"><strong>Conclusions:</strong> Clinical suspicion of otomycosis is important to prevent unnecessary use of antibiotics. Diagnosis of otomycosis is usually made by clinical findings with pruritis being most common symptom followed by otalgia. In-vitro sensitivity test is of great importance to choose the most active antifungal agents. Patients are advised to avoid removing of ear wax by stiff materials.</p>
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Sheikh, Mohd S., B. Y. Qazi y B. Rameen. "Otomycosis in Khozistan". Indian Journal of Otolaryngology and Head and Neck Surgery 45, n.º 2 (junio de 1993): 73–77. http://dx.doi.org/10.1007/bf03050699.

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