Tesis sobre el tema "Nucleotide Binding Proteins"
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Tisi, Dominic John Guiseppe. "Structural studies on nucleotide binding proteins". Thesis, Birkbeck (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391822.
Texto completoJohansson, Kenth. "Structural studies of four nucleotide binding proteins : aldehyde dehydrogenase, NADP-malate dehydrogenase and two deoxynucleoside kinases /". Uppsala : Swedish University of Agricultural Sciences, 2000. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=009416200&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Texto completoMutomba, Martha Chengetai. "Guanine nucleotide-binding proteins of Trypanosoma brucei". Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308280.
Texto completoIuga, Adriana. "Solid-state 31P NMR of nucleotide binding proteins". [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=973225238.
Texto completoHeurtel, Thuswaldner Sophie. "Nucleotide-binding Proteins in the Plant Thylakoid Membrane". Licentiate thesis, Linköping Department of Biomedicine and Surgery, Linköping University, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-7934.
Texto completoWorth, Graham Alan. "The energetics of nucleotide binding to RAS proteins". Thesis, University of Oxford, 1992. http://ora.ox.ac.uk/objects/uuid:44524415-2f2b-4601-998c-56110f332153.
Texto completoBramble, Sharyl Elizabeth. "Guanine nucleotide binding properties and attempted immunopurification of ras protein from dictyostelium discoideum". Thesis, University of British Columbia, 1987. http://hdl.handle.net/2429/26172.
Texto completoScience, Faculty of
Microbiology and Immunology, Department of
Graduate
Law, Wing-lun y 羅永倫. "Expression, purification and preliminary x-ray crystallographic studies of two nucleotide binding proteins". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46939118.
Texto completoAkam, Elizabeth Claire. "The activation of guanine nucleotide binding proteins by muscarinic acetylcholine receptor subtypes". Thesis, University of Leicester, 1999. http://hdl.handle.net/2381/29919.
Texto completoWadman, Isobel A. "The regulation of human platelet adenylate cyclase by ATP and guanine nucleotide binding proteins". Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241124.
Texto completoWong, Yung Hou. "Molecular basis of the opioid receptor-ligand interactions : the role of guanine nucleotide-binding proteins". Thesis, University of Cambridge, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303263.
Texto completoSarma, Ranjana. "Investigations of nucleotide-dependent electron transfer and substrate binding in nitrogen fixation and chlorophyll biosynthesis". Thesis, Montana State University, 2009. http://etd.lib.montana.edu/etd/2009/sarma/SarmaR1209.pdf.
Texto completoChakrabarti, Partha Pratim. "Biochemical and biophysical analysis of the GTPase activating proteins of the small guanine nucleotide binding protein Rap1 and RheB". [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=975809598.
Texto completoAdhikari, Anirban. "Regulation of guanine nucelotide exchange in inhibitory G protein alpha subunit by activator of G protein signaling 3 and novel regulatory peptides". Embargoed access until after 12/19/2006, 2005. http://www4.utsouthwestern.edu/library/ETD/etdDetails.cfm?etdID=114.
Texto completoMahajan, Shikha. "Protein Profiling of Adenine Nucleoside and Nucleotide Analogs Binding Proteins Using N6-Biotinylated-8-azidoadenosine Analogs as Affinity Based Protein Profiling Probes". Scholar Commons, 2012. http://scholarcommons.usf.edu/etd/4139.
Texto completoGrady, Amanda Ellen. "The regulation of the type 5 cyclic nucleotide phosphodiesterase in airway smooth muscle by metal ions and small molecular weight proteins". Thesis, University of Strathclyde, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366810.
Texto completoMeier, Katharina [Verfasser], Jörg [Akademischer Betreuer] [Gutachter] Durner y Brigitte [Gutachter] Poppenberger-Sieberer. "Cyclic nucleotide signaling in Arabidopsis thaliana and the identification of cGMP binding proteins / Katharina Meier ; Gutachter: Jörg Durner, Brigitte Poppenberger-Sieberer ; Betreuer: Jörg Durner". München : Universitätsbibliothek der TU München, 2017. http://d-nb.info/1128819368/34.
Texto completoRudolf, Jana. "Characterisation of XPD from Sulfolobus acidocaldarius : an iron-sulphur cluster containing DNA repair helicase". Thesis, St Andrews, 2007. http://hdl.handle.net/10023/159.
Texto completoLee, Meng-Tse. "Catalytic Mechanisms in Sec7 and Vps9 Domain Exchange Factors for Arf and Rab GTPases: A Dissertation". eScholarship@UMMS, 2012. https://escholarship.umassmed.edu/gsbs_diss/598.
Texto completoCarmine, Andrea. "On Parkinson's disease and schizophrenia : case control studies, cellular localization and modelling of candidate genes /". Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-671-5.
Texto completoRaper, Jayne. "Guanine nucleotide binding protein function in T.B. Brucei". Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305533.
Texto completoGorman, Christine. "The interaction of Ras with Raf and other potential effectors". Thesis, Imperial College London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312373.
Texto completoSaiu, P. "Structural and functional studies on nucleotide binding to AMP-activated protein kinase". Thesis, University College London (University of London), 2010. http://discovery.ucl.ac.uk/645676/.
Texto completoCarie, Adam E. "Tumor suppressive effects of the Beta-2 adrenergic receptor and the small GTPase RhoB". [Tampa, Fla.] : University of South Florida, 2008. http://purl.fcla.edu/usf/dc/et/SFE0002330.
Texto completoDaumke, Oliver. "Structural and functional analysis of the GTPase activating protein of the small guanine nucleotide binding protein Rap1". [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=971950806.
Texto completoThain, Alison. "An analysis of the nucleotide requirements for DNA binding by the human pallomavirus type 16 E2 protein". Thesis, University of Bristol, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.245392.
Texto completoWreggett, Keith Allen. "Characterization of the interaction of the D2-Dopamine receptor with a guanine nucleotide-binding protein". Thesis, McGill University, 1985. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=73965.
Texto completoBrown, Lesley Ann. "Guanine nucleotide-binding protein function in myocytes isolated from normal, failing and beta-adrenoceptor desensitised myocardium". Thesis, Imperial College London, 1991. http://hdl.handle.net/10044/1/46688.
Texto completoChen, Xi Lin. "Régulation de l'apoptose des lymphocytes T par GIMAP5 (GTPase of Immune Associated Nucleotide Binding Protein 5)". Thèse, Université de Sherbrooke, 2015. http://hdl.handle.net/11143/7593.
Texto completoRésumé : La survie à long terme des lymphocytes T en état de repos est essentielle pour maintenir leurs nombres dans les organes lymphoïdes secondaires. Le récepteur antigénique des cellules T (TCR) en contact avec les peptides du soi / CMH et en synergie avec l'IL-7 induit des signaux anti-apoptotiques pour favoriser la survie des cellules T. Ces stimuli extrinsèques sont également impliqués dans le métabolisme et la survie des cellules T grâce à la régulation de plusieurs voies de signalisation dont la voie phosphatidyl-inositol-3 kinase (PI3K) /AKT. Chez la souris et chez le rat, la perte de l’activité de GIMAP5 (GTPase of Immune Associated Nucleotide Binding Protein 5), provoque une lymphopénie T périphérique en raison de la mort spontanée des cellules T. Le mécanisme sous-jacent responsable de la fonction de survie de GIMAP5 dans les lymphocytes T reste largement inconnu. Nous avons observé que les cellules de rats déficients en GIMAP5, après stimulation par complexe TCR, montrent un afflux de calcium (Ca[indice supérieur 2+]) réduit provenant du milieu extracellulaire. Dans cette thèse, J’ai caractérisé le mécanisme d’action de GIMAP5 dans la régulation de l'homéostasie du Ca[indice supérieur 2+], ainsi que les voies de signalisation modulées par GIMAP5 pour faciliter la survie des cellules T. Tout d'abord, j’ai étudié si GIMAP5 empêche l’apoptose des lymphocytes T en affectant la capacité des mitochondries à réguler la concentration du Ca[indice supérieur 2+], ce qui est nécessaire pour soutenir l’influx de Ca[indice supérieur 2+]. J’ai trouvé que l’accumulation du Ca[indice supérieur 2+] mitochondrial après l’entrée capacitive de Ca[indice supérieur 2+] est défectueuse dans les cellules T de rat déficientes en Gimap5. La disruption des microtubules, mais pas du cytosquelette d'actine, abroge la séquestration du Ca[indice supérieur 2+] mitochondrial dans les cellules T primaires de rat, mais pas dans les cellules T déficientes en Gimap5. J’ai observé que les cellules T provenant de souris déficientes en Gimap5 démontrent une diminution de l’entrée de Ca[indice supérieur 2+]. De plus, la prolifération des cellules T déficientes en Gimap5 est diminuée suite à la stimulation du TCR. En outre, la phosphorylation de STAT5 induit par l'IL-7 est diminuée dans les cellules T CD4[indice supérieur +] de souris déficientes en Gimap5. Également, la perte de Gimap5 aboutit à une activation accrue de la cible mammalienne de la rapamycine (mTOR), indépendamment de la protéine phosphatase 2A (PP2A) ou de la protéine kinase activée par l'AMP (AMPK). Au lieu de cela, l'activation constitutive de la voie PI3K contribue à une forte activation spontanée de mTOR. Collectivement, la fonction de survie de GIMAP5 dans les lymphocytes T peut être liée à la régulation de différentes voies de signalisation. GIMAP5 facilite la fonction, microtubule dépendant, des mitochondries dans leurs actions de régulation du Ca[indice supérieur 2+] après l’entrée capacitive de Ca[indice supérieur 2+]. GIMAP5 est nécessaire pour intégrer les signaux de survie produits suite à l'activation du TCR et de l’IL-7R, qui pourrait être associée à la régulation de l'activité PI3K / AKT / mTOR.
Levine, Kara B. "Identification of the Human Erythrocyte Glucose Transporter (GLUT1) ATP Binding Domain: A Dissertation". eScholarship@UMMS, 1999. https://escholarship.umassmed.edu/gsbs_diss/247.
Texto completoRocha, Aline Marubayashi. "Screening mutacional do gene HINT1 em uma amostra da população brasileira com quadro clínico de CMT recessivo". Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/17/17140/tde-06012017-112710/.
Texto completoThe large heterogeneous group of inherited peripheral neuropathies are among the most common causes of sensory loss and muscle weakness in children and adolescents. At least 84 genes are involved in inherited sensorymotor neuropathies (NSMH), being the demyelinating and axonal autosomaldominant and the X-linked neuropathies their most common forms of inheritance, and the demyelinating and axonal autosomal-recessive and not yet classified forms the most rare ones. The HINT1 gene, with 3 exons and located on chromosome 5, encodes the protein Histidine triad nucleotide binding protein 1, a regulatory transcriptional variant (mRNA) that hydrolyzes substrates. Recently, mutations in HINT1 were also related to axonal neuropathy with neuromyotonia (ARCMT2-NM), and therefore to CMT. The objective of this study was the mutational screening of the HINT1 gene in a sample of the Brazilian population with clinical recessive CMT (CMT2-AR), and 1 silent mutation previously described, 1 intronic polymorphism and 1 exonic polymorphism, both also known, were founded. It was then concluded that mutations in the HINT1 gene are not responsible for CMT2-AR in this particular sample of the Brazilian population.
Parikh, Ishita. "Expression and Splicing of Alzheimer’s Disease Risk Gene Phosphatidylinositol-Binding Clathrin Assembly Protein". UKnowledge, 2014. http://uknowledge.uky.edu/physiology_etds/18.
Texto completoYe, Zhengmao Ting Jenny P. Y. "Modulation of innate immunity by nucleotide binding biochemical and functional characterization of a CATERPILLER/NLR protein, Monarch-1/NLRP12 /". Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,1407.
Texto completoTitle from electronic title page (viewed Apr. 25, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Microbiology and Immunology." Discipline: Microbiology and Immunology; Department/School: Medicine.
Johnson, Reed Findley. "Characterization of the 3' terminal 42 nucleotide host protein binding element of the mouse hepatitis virus 3' untranslated region". Texas A&M University, 2003. http://hdl.handle.net/1969/125.
Texto completoKshetri, Man B. "N-TERMINAL DOMAIN OF rRNA METHYLTRANSFERASE ENZYME RsmC IS IMPORTANT FOR ITS BINDING TO RNA AND RNA CHAPERON ACTIVITY". Kent State University Honors College / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors1621007414429417.
Texto completoWiles, Natasha Shawn. "Identification of Regulatory Binding Sites and Corresponding Transcription Factors Involved in the Developmental Control of 5'-nucleotidase Expression in Dictyostelium discoideum". Diss., Virginia Tech, 2005. http://hdl.handle.net/10919/27810.
Texto completoPh. D.
Sanghvi, Rashesh. "In Silico Analysis Shows That Single Aminoacid Variations In Rhesus Macacque Fcγreceptor Affect Protein Stability And Binding Affinity To IgG1". Digital Archive @ GSU, 2013. http://digitalarchive.gsu.edu/biology_theses/47.
Texto completoHaupt, Melina. "Investigations on the nucleotide binding domain of KdpB by NMR spectroscopy and solution structure of an [alpha]4[beta]7 [alpha-4-beta-7] integrin antagonist". [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=972764356.
Texto completoLin, Chien-Ling. "Studies on the Regulation of Cytoplasmic Polyadenylation Element-Binding Protein: A Dissertation". eScholarship@UMMS, 2012. https://escholarship.umassmed.edu/gsbs_diss/583.
Texto completoXia, Yu [Verfasser]. "The role of nucleotide-binding oligomerization domain containing protein 2 (Nod 2) in coxsackievirus B3 induced myocarditis in mice model / Yu Xia". Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2014. http://d-nb.info/1064113559/34.
Texto completoJuno, Jennifer. "Contribution of guanine nucleotide binding protein beta polypeptide 3 (GNB3) and lymphocyte activation gene 3 (LAG-3) to HIV susceptibility and immune dysfunction". Permanyer, 2010. http://hdl.handle.net/1993/23948.
Texto completoStraza, Michael W. "A Tale of Two ARFs: Tumor Suppressor and Anti-viral Functions of p14ARF: A Dissertation". eScholarship@UMMS, 2010. https://escholarship.umassmed.edu/gsbs_diss/472.
Texto completoBelk, Jonathan Philip. "A Characterization of Substrates and Factors Involved in Yeast Nonsense-Mediated mRNA Decay: A Dissertation". eScholarship@UMMS, 2002. https://escholarship.umassmed.edu/gsbs_diss/65.
Texto completoCook, Neil James. "Le gmp cyclique et la phototransduction chez les vertebres". Strasbourg 1, 1986. http://www.theses.fr/1986STR13147.
Texto completoMadera, Dmitri. "Cooperating Events in Core Binding Factor Leukemia Development: A Dissertation". eScholarship@UMMS, 2011. https://escholarship.umassmed.edu/gsbs_diss/532.
Texto completoRedekar, Neelam R. "Genome and Transcriptome Based Characterization of Low Phytate Soybean and Rsv3-Type Resistance to Soybean Mosaic Virus". Diss., Virginia Tech, 2015. http://hdl.handle.net/10919/75118.
Texto completoPh. D.
Ertekin, Ozlem. "The Effect Of Indole Acetic Acid, Abscisic Acid, Gibberellin And Kinetin On The Expression Of Arf1 Gtp Binding Protein Of Pea (pisum Sativum L. Cv. Araka)". Master's thesis, METU, 2007. http://etd.lib.metu.edu.tr/upload/12608902/index.pdf.
Texto completoM of each hormone for 3 times on alternate days. Protein extraction, cell fractionation,Western blot was carried out and immunoblot analysis was conducted with AtARF1 polyclonal antibodies. It was shown that, in pea shoots, abscisic acid and gibberellin increases the inactive GDP bound ARF1 by hydrolyzing ARF-GTP through activating ARFGTPase activating protein (ARF-GAP) or partially inhibiting ARF-Guanine Nucleotide Exchange Factor (ARF-GEF). In roots, ARF-GDP (cytosolic fraction), ARF-GTP (microsomal fraction) and total amount of ARF1 (13.000 x g supernatant fraction) were down regulated by ~11, ~19 and ~11 fold respectively with the application of gibberellin
and by ~11, ~7 and ~3 fold respectively with the application of abscisic acid
when compared to control plants. These results indicate the importance of plant hormones in the regulation of ARF1 in pea.
Laine, Jennifer M. "Protein Ligand Interactions Probed by NMR: A Dissertation". eScholarship@UMMS, 2012. https://escholarship.umassmed.edu/gsbs_diss/617.
Texto completoIsobe, Yuu. "Direct evidence for the age-dependent demise of GNAS-mutated cells in oral fibrous dysplasia". Kyoto University, 2019. http://hdl.handle.net/2433/242351.
Texto completoPagano, John M. Jr. "RNA Recognition by the Caenorhabditis elegans Embryonic Determinants MEX-5 and MEX-3: A Dissertation". eScholarship@UMMS, 2010. https://escholarship.umassmed.edu/gsbs_diss/486.
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