Literatura académica sobre el tema "Neuroblastes"
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Artículos de revistas sobre el tema "Neuroblastes"
Cabet, Sara, Laurent Guibaud y Damien Sanlaville. "Variations pathogènes de NDE1 et microlissencéphalie". médecine/sciences 36, n.º 10 (octubre de 2020): 866–71. http://dx.doi.org/10.1051/medsci/2020157.
Texto completoBroadus, J. y C. Q. Doe. "Evolution of neuroblast identity: seven-up and prospero expression reveal homologous and divergent neuroblast fates in Drosophila and Schistocerca". Development 121, n.º 12 (1 de diciembre de 1995): 3989–96. http://dx.doi.org/10.1242/dev.121.12.3989.
Texto completoSkeath, J. B. "The Drosophila EGF receptor controls the formation and specification of neuroblasts along the dorsal-ventral axis of the Drosophila embryo". Development 125, n.º 17 (1 de septiembre de 1998): 3301–12. http://dx.doi.org/10.1242/dev.125.17.3301.
Texto completoMcDonald, J. A. y C. Q. Doe. "Establishing neuroblast-specific gene expression in the Drosophila CNS: huckebein is activated by Wingless and Hedgehog and repressed by Engrailed and Gooseberry". Development 124, n.º 5 (1 de marzo de 1997): 1079–87. http://dx.doi.org/10.1242/dev.124.5.1079.
Texto completoDoe, C. Q. "Molecular markers for identified neuroblasts and ganglion mother cells in the Drosophila central nervous system". Development 116, n.º 4 (1 de diciembre de 1992): 855–63. http://dx.doi.org/10.1242/dev.116.4.855.
Texto completoDormand, E. L. y A. H. Brand. "Runt determines cell fates in the Drosophila embryonic CNS". Development 125, n.º 9 (1 de mayo de 1998): 1659–67. http://dx.doi.org/10.1242/dev.125.9.1659.
Texto completoGiansanti, M. G., M. Gatti y S. Bonaccorsi. "The role of centrosomes and astral microtubules during asymmetric division of Drosophila neuroblasts". Development 128, n.º 7 (1 de abril de 2001): 1137–45. http://dx.doi.org/10.1242/dev.128.7.1137.
Texto completoCui, X. y C. Q. Doe. "The role of the cell cycle and cytokinesis in regulating neuroblast sublineage gene expression in the Drosophila CNS". Development 121, n.º 10 (1 de octubre de 1995): 3233–43. http://dx.doi.org/10.1242/dev.121.10.3233.
Texto completoUdolph, G., J. Urban, G. Rusing, K. Luer y G. M. Technau. "Differential effects of EGF receptor signalling on neuroblast lineages along the dorsoventral axis of the Drosophila CNS". Development 125, n.º 17 (1 de septiembre de 1998): 3291–99. http://dx.doi.org/10.1242/dev.125.17.3291.
Texto completoBerger, Christian, Joachim Urban y Gerhard M. Technau. "Stage-specific inductive signals in the Drosophila neuroectoderm control the temporal sequence of neuroblast specification". Development 128, n.º 17 (1 de septiembre de 2001): 3243–51. http://dx.doi.org/10.1242/dev.128.17.3243.
Texto completoTesis sobre el tema "Neuroblastes"
Goupil, Alix. "Genome instability : from genome content variations to gene expression plasticity". Electronic Thesis or Diss., Université Paris sciences et lettres, 2021. http://www.theses.fr/2021UPSLS053.
Texto completoMost animal cells are diploid, containing two copies of each chromosome. Establishment of proper bipolar mitotic spindle containing two centrosomes, one at each pole contributes to accurate chromosome segregation. This is essential for the maintenance of genome stability, tissue and organism homeostasis. However, numerical deviations to the diploid set are observed in healthy tissues. Polyploidy is the doubling of the whole chromosome set and aneuploidy concerns the gain or loss of whole chromosomes. Importantly, whole genome duplications and aneuploidy have also been associated to pathological conditions. For example, variations to genome content are associated with chromosome instability and cancer development, however their exact contribution to cancer genome remains poorly understood.In the first part of my PhD project, I investigated the consequences of polyploidy during cell division. I found that the presence of extra DNA and extra centrosomes generated invariably multipolar spindles. Then I identified contributors to the multipolar status using in vivo approaches in Drosophila neural stem cells and in vitro culture of cancer cells. Further I combined DNA and spindle perturbations with computer modelling and found that in polyploid cells, the presence of excessive DNA acts as a physical barrier blocking spindle pole coalescence and bipolarity. Indeed, laser ablation to disrupt and increase in microtubule stability and length to bypass the DNA-barrier could rescue bipolar spindle formation. This discovery challenges the current view that suggested extra-centrosomes as only contributor to spindle multipolarity and provides a rational to understand chromosome instability typical of polyploid cells.The aim of the second part of my PhD project was to generate a novel tool to quantitively probe chromosome loss in vivo in Drosophila tissues. Aneuploidy has been observed in various physiological tissues, however the frequency of this error remained highly debatable. In addition, tools developed so far to assess aneuploidy lack a temporal dimension. To circumvent this, I used the expression of a GFP report gene driven by the GAL4/UAS system and its inhibition by GAL80. In principle, the random loss of the chromosome carrying the GAL80 sequence leads to GFP appearance in aneuploid cells that can therefore be followed in live tissues. I found that chromosome loss was extremely infrequent in most tissues of the wild type fly. This tool combined with fluorescent marker and/or tested in various genetic background, might help understanding mechanisms behind aneuploidy genesis and outcome in vivo.While developing this tool, I discovered that in the larval brain, GFP cells where not a by-product of chromosome loss but rather an unexpected mis-regulation in the expression of the GAL80 gene. These results have strong implications for the Drosophila community as it can result in false positive in clonal experiments. Further, I discovered a mosaicism and plasticity of the Drosophila brain in neural stem cells for gene expression which differs from other organs and that is influenced by environmental stimuli. This possibly reflects a certain level of plasticity in the brain necessary for neuronal diversity, adaptation and survival
Thomas, Alexandre. "Rôle des microtubules lors de la division asymétrique des neuroblastes chez Drosophila melanogaster". Thesis, Rennes 1, 2020. http://www.theses.fr/2020REN1B012.
Texto completoD. melanogaster neuroblast is a neural stem cell which divides asymmetrically to generate a self-renewing neuroblast, and a GMC committed in a differentiation pathway. This division is asymmetric by the differential segregation of cell fate determinants, inherited by the two daughter cells, but also asymmetric by the size, where the neuroblast is larger than the GMC. Originally two pathways have been identified, cell polarity and central spindle, for the control of asymmetric cleavage furrow positioning in these cells. We revealed that the determination and maintenance of cleavage furrow position require a third mechanism involving the peripheral microtubules. This microtubule sub-population is observed during cytokinesis in contact with the cleavage furrow. Moreover, we showed that the position of the central spindle is spatially separated from the cleavage furrow position, being slightly shifted toward the apical pole, suggesting that it is not required for its determination. Furthermore, we highlighted that the diminution of peripheral microtubules is associated with a relocalisation of the cleavage furrow toward the central spindle position, leading to a less asymmetric division. To conclude this study reveals that a third mechanism, depending on peripheral microtubules, is essential for the fidelity of the neuroblast asymmetric division in Drosophila melanogaster
Chaulet, Maxime. "Rôle du cil primaire dans la migration des neuroblastes du courant de migration rostrale". Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS191.
Texto completoThe aim of my thesis was to better understand the mechanisms underlying the role of the primary cilium (PC) in neuronal migration. Our study model is the tangential migration in the rostral migratory stream (RMS) in the postnatal and adult mice. Neuroblasts of the CMR show a saltatory migration with pause and nucleokinesis and a stereotyped centrosome movement. In a first study with preliminary results, we compared the migration between postnatal (P10) and young adult (P30) stages by live imaging on acute brain slices, as well as the effect of genetic ablation of the PC at these two ages. We showed that migrations are different between these two stages and that genetic ablation of the PC impaired differentially migration parameters. In a second study, submitted for publication soon, we analysed cAMP dynamics during postnatal migration. We observed a dynamic cAMP hotspot cyclically at the centrosome, at the basis of the PC. We show that ciliary-produced cAMP diffuses to the centrosome, where it activates locally the cAMP-dependent Protein Kinase A (PKA). Genetic ablation of the cilium and knock-down of the ciliary Adenylate Cyclase 3 lead to the hotspot disappearance. They also affect migration with defective centrosome/nucleus coupling leading to altered nucleokinesis, which is recapitulated by PKA genetic delocalization. We thus show that PC and centrosome act as a signalling unit, linked by ciliary cAMP diffusion regulating the rhythmicity of salutatory migration at the centrosome
Blanc, Étienne. "Identification de gènes associés à la dissémination métastatique dans un modèle de neuroblastes malins humains". Paris 11, 2004. http://www.theses.fr/2004PA11TO30.
Texto completoBoudannaoui, Saïda. "Expression des potentialites adrenergiques acquises lors de l'induction neurogene par des neuroblastes embryonnaires en differenciation in vitro". Toulouse 3, 1988. http://www.theses.fr/1988TOU30118.
Texto completoBoudannaoui, Saïda. "Expression des potentialités adrénergiques acquises lors de l'induction neurogène par des neuroblastes embryonnaires en différenciation in vitro". Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb376121292.
Texto completoButruille, Lucile. "La neurogénèse hypothalamique adulte : sensibilité à la photopériode, devenir des neuroblastes et rôle dans la fonction de reproduction". Thesis, Tours, 2017. http://www.theses.fr/2017TOUR4032/document.
Texto completoNumerous studies have demonstrated the presence of neurogenic processes in the adult hypothalamus, a diencephalon structure involved in the regulation of many physiological functions. The objective of my thesis was to study the mechanisms of plasticity, such as adult neurogenesis, and their involvement in the neuroendocrine control of the reproductive function. In sheep, a seasonal species, reproduction is controlled by the photoperiod. Seasonal variations in the duration of the day lead to seasonal variations in the proliferation rate and in the number of new neurons. After identifying the cellular components of the hypothalamic neurogenic niche in this species, we demonstrated their sensitivity to photoperiod. A longitudinal analysis in neuroimaging will aimed to determine the fate of new hypothalamic neurons. A functional study in mice showed that dividing hypothalamic GFAP positive cells have a neurogenic potential and their ablation leads to severe impairment of the reproductive function in the male
MAS, CHRISTOPHE. "Clonage et caracterisation de genes impliques dans la proliferation des neuroblastes du telencephale un strategie d'identification de genes candidats a des maladies du neurodeveloppement". Paris 7, 1999. http://www.theses.fr/1999PA077156.
Texto completoL'Hostis-Guidet, Anne. "Des xénopes transgéniques pour l’étude de la neurogénèse : analyse et propriétés fonctionnelles de neuroblastes exprimant un gène rapporteur sous contrôle du promoteur de NeuroD". Rennes 1, 2007. http://www.theses.fr/2007REN1S139.
Texto completoElectrical activity involved in neurogenesis during embryonic development of vertebrates is dependant of calcium permeabilities whose characterization requires the ability to locate neuroblasts. Transgenic lines expressing EGFP under the control of the NeuroD (neuronal differentiation factor) and the Neuro β-tubulin (neuronal marker) promoters were produced in Xenopus laevis. The transgene expression is restricted to neurons and non differentiated cells exclusively in nervous system in these transgenic animals. Confocal calcium imaging suggests that EGFP expressing cells with the NeuroD promoter would have different functional properties compared to cells without transgene expression. The combination of transgenesis and functional cellular imaging is a promising tool for characterization of neuroblasts expressing bHLH NeuroD factor
Basille, Magali. "Contribution à l'étude des récepteurs du pituitary adenylate cyclase-activating polypeptide (PACAP) au cours de l'ontogénèse du cervelet de rat. Recherche d'une activité trophique potentielle du PACAP sur les neuroblastes cérébelleux". Rouen, 1998. http://www.theses.fr/1998ROUES010.
Texto completoLibros sobre el tema "Neuroblastes"
M, Brodeur Garrett, ed. Neuroblastoma. Amsterdam: Elsevier, 2000.
Buscar texto completoIm Himmel warten Bäume auf dich: Die Geschichte eines viel zu kurzen Lebens. Augsburg: Weltbild, 2001.
Buscar texto completoSchor, Nina Felice. The neurology of neuroblastoma: Neuroblastoma as a neurobiological disease. Norwell, Mass: Kluwer Academic, 2002.
Buscar texto completoSchor, Nina Felice. The Neurology of neuroblastoma: Neuroblastoma as a neurobiological disease. Norwell, Mass: Kluwer Academic, 2002.
Buscar texto completoBreisgau, Universität Freiburg im, ed. Vom bekannten Unbekannten, vom unbekannten Unbekannten und vom unbekannten Bekannten: Neuartige Dimethylcyclohexanon-Anellierungen als Schlüsselschritte in der Totalsynthese terpenoider Naturstoffe : Totalsynthese von (±)-Isoacanthodoral. Desymmetrisierung prochiraler Sulfoxide : eine neuartige asymmetrische Synthese von Sulfoxiden. Hybride aus Butan-1,4-diylbis(methansulfonat) und Benzylguanidin zur Therapie des Neuroblastoms. [S.l: s.n.], 2013.
Buscar texto completoR, McCready V. y Fullbrook Ann, eds. Neuroblastoma: MIBG in its diagnosis and management. London: Springer-Verlag, 1989.
Buscar texto completo1925-, Evans Audrey E., ed. Advances in neuroblastoma research 3: Proceedings of the Fifth Symposium on Advances in Neuroblastoma Research, held in Philadelphia, Pennsylvania, May 28-30, 1990. New York: Wiley-Liss, 1991.
Buscar texto completo1925-, Evans Audrey E., ed. Advances in neuroblastoma research 2: Proceedings of the Fourth Symposium on Advances in Neuroblastoma Research held in Philadelphia, Pennsylvania, May 14-16, 1987. New York: Liss, 1988.
Buscar texto completoSchor, Nina Felice. Neurology of Neuroblastoma: Neuroblastoma As a Neurobiological Disease. Springer London, Limited, 2012.
Buscar texto completoSchor, Nina Felice. The Neurology of Neuroblastoma: Neuroblastoma as a Neurobiological Disease. Springer, 2002.
Buscar texto completoCapítulos de libros sobre el tema "Neuroblastes"
Berthold, F. "Neuroblastom". En Kompendium Internistische Onkologie, 5567–81. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/3-540-31303-6_273.
Texto completoBerthold, F. "Neuroblastom". En Kompendium Internistische Onkologie, 6450–54. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/3-540-31303-6_374.
Texto completoKremens, Bernhard y Angelika Eggert. "Neuroblastom". En Uroonkologie, 771–78. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-01382-9_30.
Texto completoImbach, Paul. "Neuroblastom". En Kompendium Kinderonkologie, 157–71. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-43485-7_11.
Texto completoEggert, A., T. Simon, B. Hero, H. Lode, R. Ladenstein, M. Fischer y F. Berthold. "Neuroblastom". En Pädiatrische Hämatologie und Onkologie, 419–39. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-43686-8_24.
Texto completoBerthold, F. "Neuroblastom". En Kompendium Internistische Onkologie Standards in Diagnostik und Therapie, 758–62. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-662-42627-2_91.
Texto completoHero, Barbara y Holger Christiansen. "Neuroblastom". En Die Onkologie, 1481–95. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-79725-8_73.
Texto completoBerthold, F. "Neuroblastom". En Kompendium Internistische Onkologie, 1805–19. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-662-12175-7_92.
Texto completoSimon, Thorsten, Barbara Hero, Matthias Fischer, Holger N. Lode y Angelika Eggert. "Neuroblastom". En Springer Reference Medizin, 1–14. Berlin, Heidelberg: Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-46764-0_7-2.
Texto completoBerthold, F. "Neuroblastom". En Therapiekonzepte Onkologie, 936–48. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-662-10493-4_42.
Texto completoActas de conferencias sobre el tema "Neuroblastes"
Chou, Szu-Yuan, Chao-Min Cheng, Yi-Wen Lin, Chih-Cheng Chen y Philip R. LeDuc. "Effects of Mechanical Strain on Structural and Actin-Binding Proteins in Neuroblasts". En ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-204747.
Texto completoKong, Jun, Hiroyuki Shimada, Kim Boyer, Joel Saltz y Metin Gurcan. "IMAGE ANALYSIS FOR AUTOMATED ASSESSMENT OF GRADE OF NEUROBLASTIC DIFFERENTIATION". En 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro. IEEE, 2007. http://dx.doi.org/10.1109/isbi.2007.356788.
Texto completoKong, Jun, Olcay Sertel, Hiroyuki Shimada, Kim Boyer, Joel Saltz y Metin Gurcan. "Computer-Aided Grading of Neuroblastic Differentiation: Multi-Resolution and Multi-Classifier Approach". En 2007 IEEE International Conference on Image Processing. IEEE, 2007. http://dx.doi.org/10.1109/icip.2007.4379881.
Texto completoBugia, Luis, Daniel Nowak, Nicole Rotter y Annette Affolter. "Wiederkehrendes Neuroblastom des Riechorgans: Eine chirurgische Odyssee und das unerforschte Terrain der adjuvanten Therapien". En 95. Jahresversammlung Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V., Bonn. Georg Thieme Verlag KG, 2024. http://dx.doi.org/10.1055/s-0044-1784079.
Texto completoKneer, K., CS Lisson, A. Boos, C. Otto, G. Glatting, C. Beltinger, M. Beer, V. Prasad y AJ Beer. "Prognostischer Wert der Texturanalyse und bildbasierter Biomarker der MRT und Iod-123-MIBG-Szintigrafie bei Neuroblastom-Patienten". En NuklearMedizin 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1683676.
Texto completoTeschner, M., W. Nuss, G. Brandes, A. Warnecke, T. Lenarz y K. Wissel. "Effekte von Omega-3-Fettsäuren und L-Carnitin auf die Stoffwechselaktivität der humanen Neuroblastom- (SH-SY5Y) und der murinen Corti-Organ (HEI-OC1) Zelllinie". En Abstract- und Posterband – 91. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Welche Qualität macht den Unterschied. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1711780.
Texto completoBeeres, M., L. Bogdan, C. Polkowski, B. Kaltenbach, S. Boettger, TJ Vogl, T. Klingebiel y T. Gruber-Rouh. "Vergleich der radialen VIBE-Sequenz ohne atem-trigger mit einer atem-getriggerten T1 Flash-Sequenz in MRT-Abdomen Staging-Untersuchungen von Patienten mit Neuroblastom Tumorerkrankung". En Zukunft sichtbar machen – 55. Jahrestagung der Gesellschaft für Pädiatrische Radiologie 2018. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1667244.
Texto completoTeschner, M., K. Wissel, G. Brandes, T. Lenarz y W. Nuss. "Omega-3-Fettsäuren im Verbund mit L-Carnitin wirken auf die Stoffwechselaktivität der humanen Neuroblastom- (SH-SY5Y) und der murinen Corti-Organ (HEI-OC1) Zelllinie". En 100 JAHRE DGHNO-KHC: WO KOMMEN WIR HER? WO STEHEN WIR? WO GEHEN WIR HIN? Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1728272.
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