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Literatura académica sobre el tema "N-alkylated aromatic oligoamides"
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Artículos de revistas sobre el tema "N-alkylated aromatic oligoamides"
Akhdar, Ayman, Arnaud Gautier, Thomas Hjelmgaard y Sophie Faure. "N ‐Alkylated Aromatic Poly‐ and Oligoamides". ChemPlusChem 86, n.º 2 (febrero de 2021): 298–312. http://dx.doi.org/10.1002/cplu.202000825.
Texto completoArrata, Irene, Anna Barnard, Darren C. Tomlinson y Andrew J. Wilson. "Interfacing native and non-native peptides: using Affimers to recognise α-helix mimicking foldamers". Chemical Communications 53, n.º 19 (2017): 2834–37. http://dx.doi.org/10.1039/c6cc09395g.
Texto completoHjelmgaard, Thomas, Olivier Roy, Lionel Nauton, Malika El-Ghozzi, Daniel Avignant, Claude Didierjean, Claude Taillefumier y Sophie Faure. "Macrocyclic arylopeptoids – a novel type of cyclic N-alkylated aromatic oligoamides forming nanotubular assemblies". Chem. Commun. 50, n.º 27 (2014): 3564–67. http://dx.doi.org/10.1039/c4cc00821a.
Texto completoBarnard, Anna, Kérya Long, David J. Yeo, Jennifer A. Miles, Valeria Azzarito, George M. Burslem, Panchami Prabhakaran, Thomas A. Edwards y Andrew J. Wilson. "Orthogonal functionalisation of α-helix mimetics". Org. Biomol. Chem. 12, n.º 35 (2014): 6794–99. http://dx.doi.org/10.1039/c4ob00915k.
Texto completoTesis sobre el tema "N-alkylated aromatic oligoamides"
Akhdar, Ayman. "Synthesis, Modification And Click Of Arylopeptoids Using Carbene-Based Catalysts". Electronic Thesis or Diss., Université Clermont Auvergne (2021-...), 2022. http://www.theses.fr/2022UCFAC117.
Texto completoArylopeptoids (i.e. oligomeric N-substituted aminomethyl benzamides) is a class of peptoid-inspired oligoamides with aromatic backbone. They retain advantageous features of peptoids such as straightforward synthesis by submonomer approach and conformational preferences governed by cis-trans isomerism of N,N-disubstituted amides. These N-alkylated aromatic oligoamides may be developed as proteomimetics or scaffolds for multivalent display. The aim of this thesis was to explore the chemical diversity accessible from linear and cyclic arylopeptoids through Click chemistry using Copper carbene as catalyst. First, access and properties of Copper (I)-N-heterocyclic carbene catalyst was exposed. Also, an extension of the quantitative NMR was presented to study the purity of this catalyst and other organometallic compounds. The development of an efficient CuAAC protocol on-resin using Copper (I)-N-heterocyclic carbene catalyst for the functionalization of arylopeptoids has allowed the efficient preparation of a library of linear oligomers carrying several triazole-type side chains. Beside, combinatorial and sequential approaches have been implemented leading to huge accessible chemical diversity. Post-modification of the triazoles into triazoliums has led to several series of triazolium-based arylopeptoids exhibiting amphipathic character. Their antibacterial activity against a panel of bacterial strains has been evaluated. The access to 3-dimensional crown- and tube-like structures from constrained arylopeptoid macrocycles by CuAAC reaction using the Cu-NHC catalyst also proved to be efficient with a selectivity depending on the spatial preorganization of the cyclic core and proper choice of the NHC catalyst. Finally, the access to H-shaped arylopeptoids was studied using CuAAC reaction on resin. Overall, this work highlights the potential of the Copper (I)-N-heterocyclic carbene as catalyst for CuAAC to perform on-resin poly-functionalization of arylopeptoids and to build complex 3D-architectures