Artículos de revistas sobre el tema "Mutant p53 gain of function"
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Stein, Yan, Varda Rotter y Ronit Aloni-Grinstein. "Gain-of-Function Mutant p53: All the Roads Lead to Tumorigenesis". International Journal of Molecular Sciences 20, n.º 24 (8 de diciembre de 2019): 6197. http://dx.doi.org/10.3390/ijms20246197.
Texto completoHall, Callum y Patricia A. J. Muller. "The Diverse Functions of Mutant 53, Its Family Members and Isoforms in Cancer". International Journal of Molecular Sciences 20, n.º 24 (7 de diciembre de 2019): 6188. http://dx.doi.org/10.3390/ijms20246188.
Texto completoChen, Sisi, Hao Yu, Michihiro Kobayashi, Rui Gao, H. Scott Boswell y Yan Liu. "Gain-of-Function Mutant p53 Enhances Hematopoietic Stem Cell Self-Renewal". Blood 124, n.º 21 (6 de diciembre de 2014): 260. http://dx.doi.org/10.1182/blood.v124.21.260.260.
Texto completoChiang, Yen-Ting, Yi-Chung Chien, Yu-Heng Lin, Hui-Hsuan Wu, Dung-Fang Lee y Yung-Luen Yu. "The Function of the Mutant p53-R175H in Cancer". Cancers 13, n.º 16 (13 de agosto de 2021): 4088. http://dx.doi.org/10.3390/cancers13164088.
Texto completoOren, M. y V. Rotter. "Mutant p53 Gain-of-Function in Cancer". Cold Spring Harbor Perspectives in Biology 2, n.º 2 (16 de diciembre de 2009): a001107. http://dx.doi.org/10.1101/cshperspect.a001107.
Texto completoAschauer, Lydia y Patricia A. J. Muller. "Novel targets and interaction partners of mutant p53 Gain-Of-Function". Biochemical Society Transactions 44, n.º 2 (11 de abril de 2016): 460–66. http://dx.doi.org/10.1042/bst20150261.
Texto completoZhang, Yanhong, Wensheng Yan y Xinbin Chen. "Mutant p53 Disrupts MCF-10A Cell Polarity in Three-dimensional Culture via Epithelial-to-mesenchymal Transitions". Journal of Biological Chemistry 286, n.º 18 (22 de marzo de 2011): 16218–28. http://dx.doi.org/10.1074/jbc.m110.214585.
Texto completoZhang, Cen, Juan Liu, Dandan Xu, Tianliang Zhang, Wenwei Hu y Zhaohui Feng. "Gain-of-function mutant p53 in cancer progression and therapy". Journal of Molecular Cell Biology 12, n.º 9 (28 de julio de 2020): 674–87. http://dx.doi.org/10.1093/jmcb/mjaa040.
Texto completoCai, Bi-He, Zhi-Yu Bai, Ching-Feng Lien, Si-Jie Yu, Rui-Yu Lu, Ming-Han Wu, Wei-Chen Wu, Chia-Chi Chen y Yi-Chiang Hsu. "NAMPT Inhibitor and P73 Activator Represses P53 R175H Mutated HNSCC Cell Proliferation in a Synergistic Manner". Biomolecules 12, n.º 3 (12 de marzo de 2022): 438. http://dx.doi.org/10.3390/biom12030438.
Texto completoZhang, Ying, Feng Yuan, Cassandra Grello, Brian Reon, Myron Gibert, Collin Dube, Anindya Dutta, Eric Holland y Roger Abounader. "CSIG-07. GAIN-OF-FUNCTION MUTANT P53 REGULATES LONG-NONCODING RNAS IN GLIOBLASTOMA". Neuro-Oncology 24, Supplement_7 (1 de noviembre de 2022): vii39—vii40. http://dx.doi.org/10.1093/neuonc/noac209.156.
Texto completoBargonetti, Jill y Carol Prives. "Gain-of-function mutant p53: history and speculation". Journal of Molecular Cell Biology 11, n.º 7 (julio de 2019): 605–9. http://dx.doi.org/10.1093/jmcb/mjz067.
Texto completoStindt, M., P. Muller y K. H. Vousden. "151 Mutant P53 Gain of Function Via P63". European Journal of Cancer 48 (julio de 2012): S36—S37. http://dx.doi.org/10.1016/s0959-8049(12)70851-1.
Texto completoBarta, Julie A., Kristen Pauley, Andrew V. Kossenkov y Steven B. McMahon. "The lung-enriched p53 mutants V157F and R158L/P regulate a gain of function transcriptome in lung cancer". Carcinogenesis 41, n.º 1 (8 de mayo de 2019): 67–77. http://dx.doi.org/10.1093/carcin/bgz087.
Texto completoZhao, Y., C. Zhang, X. Yue, X. Li, J. Liu, H. Yu, V. A. Belyi, Q. Yang, Z. Feng y W. Hu. "Pontin, a new mutant p53-binding protein, promotes gain-of-function of mutant p53". Cell Death & Differentiation 22, n.º 11 (10 de abril de 2015): 1824–36. http://dx.doi.org/10.1038/cdd.2015.33.
Texto completoZhao, Yuhan, Xuetian Yue y Wenwei Hu. "Pontin, a novel interactor of mutant p53 that promotes mutant p53 gain of function". Molecular & Cellular Oncology 3, n.º 2 (29 de julio de 2015): e1076587. http://dx.doi.org/10.1080/23723556.2015.1076587.
Texto completoAubrey, Brandon James, Andreas Strasser, Gemma Kelly, Lin Tai y Marco Herold. "Evidence for Mutant p53 Gain-of-Function Effects in Normal Haemopoietic Cells and Myc-Driven Lymphoma". Blood 124, n.º 21 (6 de diciembre de 2014): 3589. http://dx.doi.org/10.1182/blood.v124.21.3589.3589.
Texto completoRockwell, Nathan, Max Staller, Maria Cannella, Barak Cohen y Joshua Rubin. "GENE-59. NOT ALL p53 MUTATIONS ARE CREATED EQUAL: A MURINE ASTROCYTE MODEL FOR HIGH-THROUGHPUT FUNCTIONAL ASSESSMENT OF p53 MISSENSE MUTATIONS". Neuro-Oncology 21, Supplement_6 (noviembre de 2019): vi110. http://dx.doi.org/10.1093/neuonc/noz175.461.
Texto completoLakoduk, Ashley M., Cheng-Fan Lee y Ping-Hung Chen. "Gain-of-“endocytic’ function in mutant p53 cancer cells". International Journal of Biochemistry & Cell Biology 131 (febrero de 2021): 105905. http://dx.doi.org/10.1016/j.biocel.2020.105905.
Texto completoPeart, Melissa J. y Carol Prives. "Mutant p53 gain of function: The NF-Y connection". Cancer Cell 10, n.º 3 (septiembre de 2006): 173–74. http://dx.doi.org/10.1016/j.ccr.2006.08.014.
Texto completoStrano, Sabrina, Stefania Dell'Orso, Adriana Maria Mongiovi, Olimpia Monti, Eleonora Lapi, Silvia Di Agostino, Giulia Fontemaggi y Giovanni Blandino. "Mutant p53 proteins: Between loss and gain of function". Head & Neck 29, n.º 5 (2007): 488–96. http://dx.doi.org/10.1002/hed.20531.
Texto completoWang, Jieqiong. "Abstract 1035: VCP/p97 promotes pancreatic cancer growth by enhancing mutant p53 activity". Cancer Research 82, n.º 12_Supplement (15 de junio de 2022): 1035. http://dx.doi.org/10.1158/1538-7445.am2022-1035.
Texto completoXiong, Shunbin, Dhruv Chachad, Yun Zhang, Jovanka Gencel-Augusto, Mario Sirito, Vinod Pant, Peirong Yang, Chang Sun y Guillermina Lozano. "Abstract A042: Differences in gain-of-function and inhibitory effects amongst p53 mutants in vivo". Cancer Research 83, n.º 2_Supplement_2 (15 de enero de 2023): A042. http://dx.doi.org/10.1158/1538-7445.metastasis22-a042.
Texto completoVikhanskaya, F., M. K. Lee, M. Mazzoletti, M. Broggini y K. Sabapathy. "Cancer-derived p53 mutants suppress p53-target gene expression--potential mechanism for gain of function of mutant p53". Nucleic Acids Research 35, n.º 6 (1 de marzo de 2007): 2093–104. http://dx.doi.org/10.1093/nar/gkm099.
Texto completoHann, Byron y Allan Balmain. "Replication of an E1B 55-Kilodalton Protein-Deficient Adenovirus (ONYX-015) Is Restored by Gain-of-Function Rather than Loss-of-Function p53 Mutants". Journal of Virology 77, n.º 21 (1 de noviembre de 2003): 11588–95. http://dx.doi.org/10.1128/jvi.77.21.11588-11595.2003.
Texto completoRockwell, Nathan C., Wei Yang, Nicole M. Warrington, Max V. Staller, Malachi Griffith, Obi L. Griffith, Christina A. Gurnett, Barak A. Cohen, Dustin Baldridge y Joshua B. Rubin. "Sex- and Mutation-Specific p53 Gain-of-Function Activity in Gliomagenesis". Cancer Research Communications 1, n.º 3 (diciembre de 2021): 148–63. http://dx.doi.org/10.1158/2767-9764.crc-21-0026.
Texto completoRoszkowska, Katarzyna A., Aleksandra Piecuch, Maria Sady, Zdzisław Gajewski y Sylwia Flis. "Gain of Function (GOF) Mutant p53 in Cancer—Current Therapeutic Approaches". International Journal of Molecular Sciences 23, n.º 21 (31 de octubre de 2022): 13287. http://dx.doi.org/10.3390/ijms232113287.
Texto completoSchulz-Heddergott, Ramona y Ute Moll. "Gain-of-Function (GOF) Mutant p53 as Actionable Therapeutic Target". Cancers 10, n.º 6 (7 de junio de 2018): 188. http://dx.doi.org/10.3390/cancers10060188.
Texto completoFrazier, Mark W., Xiaoping He, JinLing Wang, Zhengming Gu, John L. Cleveland y Gerard P. Zambetti. "Activation of c-myc Gene Expression by Tumor-Derived p53 Mutants Requires a Discrete C-Terminal Domain". Molecular and Cellular Biology 18, n.º 7 (1 de julio de 1998): 3735–43. http://dx.doi.org/10.1128/mcb.18.7.3735.
Texto completoDonzelli, Sara, Francesca Biagioni, Francesca Fausti, Sabrina Strano, Giulia Fontemaggi y Giovanni Blandino. "Oncogenomic Approaches in Exploring Gain of Function of Mutant p53". Current Genomics 9, n.º 3 (1 de mayo de 2008): 200–207. http://dx.doi.org/10.2174/138920208784340713.
Texto completoXiong, S., H. Tu, M. Kollareddy, V. Pant, Q. Li, Y. Zhang, J. G. Jackson et al. "Pla2g16 phospholipase mediates gain-of-function activities of mutant p53". Proceedings of the National Academy of Sciences 111, n.º 30 (14 de julio de 2014): 11145–50. http://dx.doi.org/10.1073/pnas.1404139111.
Texto completoYue, Xuetian, Yuhan Zhao, Yang Xu, Min Zheng, Zhaohui Feng y Wenwei Hu. "Mutant p53 in Cancer: Accumulation, Gain-of-Function, and Therapy". Journal of Molecular Biology 429, n.º 11 (junio de 2017): 1595–606. http://dx.doi.org/10.1016/j.jmb.2017.03.030.
Texto completoZhang, Y., S. V. Coillie, J.-Y. Fang y J. Xu. "Gain of function of mutant p53: R282W on the peak?" Oncogenesis 5, n.º 2 (febrero de 2016): e196-e196. http://dx.doi.org/10.1038/oncsis.2016.8.
Texto completoYamamoto, Satomi y Tomoo Iwakuma. "Regulators of Oncogenic Mutant TP53 Gain of Function". Cancers 11, n.º 1 (20 de diciembre de 2018): 4. http://dx.doi.org/10.3390/cancers11010004.
Texto completoDeppert, Wolfgang, Thomas G�hler, Hisashi Koga y Ella Kim. "Mutant p53: ?gain of function? through perturbation of nuclear structure and function?" Journal of Cellular Biochemistry 79, S35 (2000): 115–22. http://dx.doi.org/10.1002/1097-4644(2000)79:35+<115::aid-jcb1134>3.0.co;2-u.
Texto completoRockwell, Nathan, Nicole Warrington y Joshua Rubin. "CBIO-22. p53 GAIN-OF-FUNCTION MUTATIONS DRIVE SEX SPECIFIC EFFECTS ON GLIOMA TUMORIGENESIS". Neuro-Oncology 22, Supplement_2 (noviembre de 2020): ii20. http://dx.doi.org/10.1093/neuonc/noaa215.082.
Texto completoCai, Bi-He, Yun-Chien Hsu, Fang-Yu Yeh, Yu-Rou Lin, Rui-Yu Lu, Si-Jie Yu, Jei-Fu Shaw et al. "P63 and P73 Activation in Cancers with p53 Mutation". Biomedicines 10, n.º 7 (23 de junio de 2022): 1490. http://dx.doi.org/10.3390/biomedicines10071490.
Texto completoCandelaria, Nicholes, Achuth Padmanabhan, Rainer Lanz, Kwong Wong y JoAnne S. Richards. "P53 Gain-of-Function Mutants and Steroids in Ovarian Cancer Cell Metastasis". Journal of the Endocrine Society 5, Supplement_1 (1 de mayo de 2021): A770—A771. http://dx.doi.org/10.1210/jendso/bvab048.1567.
Texto completoKalo, Eyal, Yosef Buganim, Keren E. Shapira, Hilla Besserglick, Naomi Goldfinger, Lilach Weisz, Perry Stambolsky, Yoav I. Henis y Varda Rotter. "Mutant p53 Attenuates the SMAD-Dependent Transforming Growth Factor β1 (TGF-β1) Signaling Pathway by Repressing the Expression of TGF-β Receptor Type II". Molecular and Cellular Biology 27, n.º 23 (17 de septiembre de 2007): 8228–42. http://dx.doi.org/10.1128/mcb.00374-07.
Texto completoHe, Chao, Lun Li, Xuan Guan, Li Xiong y Xiongying Miao. "Mutant p53 Gain of Function and Chemoresistance: The Role of Mutant p53 in Response to Clinical Chemotherapy". Chemotherapy 62, n.º 1 (21 de junio de 2016): 43–53. http://dx.doi.org/10.1159/000446361.
Texto completoYang, Hao, Ke Zhang, Yusheng Guo, Xin Guo, Kailong Hou, Jing Hou, Ying Luo, Jing Liu y Shuting Jia. "Gain-of-Function p53N236S Mutation Drives the Bypassing of HRasV12-Induced Cellular Senescence via PGC–1α". International Journal of Molecular Sciences 24, n.º 4 (14 de febrero de 2023): 3790. http://dx.doi.org/10.3390/ijms24043790.
Texto completoAnnor, George Kwakye. "Abstract P5-09-02: Tetrameric and monomeric gain-of-function mutant p53 interacts with chromatin". Cancer Research 82, n.º 4_Supplement (15 de febrero de 2022): P5–09–02—P5–09–02. http://dx.doi.org/10.1158/1538-7445.sabcs21-p5-09-02.
Texto completoGomes, Ana Sara, Helena Ramos, Alberto Inga, Emília Sousa y Lucília Saraiva. "Structural and Drug Targeting Insights on Mutant p53". Cancers 13, n.º 13 (3 de julio de 2021): 3344. http://dx.doi.org/10.3390/cancers13133344.
Texto completoStein, Yan, Ronit Aloni-Grinstein y Varda Rotter. "Mutant p53—a potential player in shaping the tumor–stroma crosstalk". Journal of Molecular Cell Biology 11, n.º 7 (julio de 2019): 600–604. http://dx.doi.org/10.1093/jmcb/mjz071.
Texto completoLevine, Arnold J. "Targeting Therapies for the p53 Protein in Cancer Treatments". Annual Review of Cancer Biology 3, n.º 1 (4 de marzo de 2019): 21–34. http://dx.doi.org/10.1146/annurev-cancerbio-030518-055455.
Texto completoBellazzo, Arianna, Giulio Di Minin y Licio Collavin. "Cytoplasmic gain-of-function mutant p53 contributes to inflammation-associated cancer". Molecular & Cellular Oncology 2, n.º 4 (23 de enero de 2015): e1002719. http://dx.doi.org/10.1080/23723556.2014.1002719.
Texto completoWalerych, Dawid, Kamil Lisek y Giannino Del Sal. "Multi-omics reveals global effects of mutant p53 gain-of-function". Cell Cycle 15, n.º 22 (13 de agosto de 2016): 3009–10. http://dx.doi.org/10.1080/15384101.2016.1215703.
Texto completoYan, Wensheng y Xinbin Chen. "Characterization of Functional Domains Necessary for Mutant p53 Gain of Function". Journal of Biological Chemistry 285, n.º 19 (8 de marzo de 2010): 14229–38. http://dx.doi.org/10.1074/jbc.m109.097253.
Texto completoBillant, Olivier, Gaëlle Friocourt, Pierre Roux y Cécile Voisset. "p53, A Victim of the Prion Fashion". Cancers 13, n.º 2 (13 de enero de 2021): 269. http://dx.doi.org/10.3390/cancers13020269.
Texto completoBlandino, Giovanni, Arnold J. Levine y Moshe Oren. "Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy". Oncogene 18, n.º 2 (enero de 1999): 477–85. http://dx.doi.org/10.1038/sj.onc.1202314.
Texto completoZalcenstein, Amir, Perry Stambolsky, Lilach Weisz, Martina Müller, David Wallach, Tanya M. Goncharov, Peter H. Krammer, Varda Rotter y Moshe Oren. "Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants". Oncogene 22, n.º 36 (agosto de 2003): 5667–76. http://dx.doi.org/10.1038/sj.onc.1206724.
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