Bibliografías temáticas / Mutant frequency

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Literatura académica sobre el tema "Mutant frequency"

Autor: Grafiati
Publicado: 10 de marzo de 2023

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Artículos de revistas sobre el tema "Mutant frequency"

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Curry, John, Larissa Karnaoukhova, Gabriel C. Guenette, and Barry W. Glickman. "Influence of Sex, Smoking and Age on Human hprt Mutation Frequencies and Spectra." Genetics 152, no. 3 (1999): 1065–77. http://dx.doi.org/10.1093/genetics/152.3.1065.

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Abstract Examination of the literature for hprt mutant frequencies from peripheral T cells yielded data from 1194 human subjects. Relationships between mutant frequency, age, sex, and smoking were examined, and the kinetics were described. Mutant frequency increases rapidly with age until about age 15. Afterward, the rate of increase falls such that after age 53, the hprt mutant frequency is largely stabilized. Sex had no effect on mutant frequency. Cigarette smoking increased mean mutant frequency compared to nonsmokers, but did not alter age vs. mutant frequency relationships. An hprt in viv
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Tanimoto, Koichi, Haruyoshi Tomita, Shuhei Fujimoto, Katsuko Okuzumi, and Yasuyoshi Ike. "Fluoroquinolone Enhances the Mutation Frequency for Meropenem-Selected Carbapenem Resistance in Pseudomonas aeruginosa, but Use of the High-Potency Drug Doripenem Inhibits Mutant Formation." Antimicrobial Agents and Chemotherapy 52, no. 10 (2008): 3795–800. http://dx.doi.org/10.1128/aac.00464-08.

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ABSTRACT The mutation frequency for carbapenem resistance in Pseudomonas aeruginosa strains that were selected with carbapenems was enhanced in the presence of subinhibitory concentrations of fluoroquinolones. The mutants showed either a loss of OprD activity or increased mexAB-oprM expression. The highest mutant isolation frequency was obtained by selection with meropenem, while doripenem inhibited mutant growth.
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Magin, Gregory K., Steven H. Robison, Nancy Breslin, Richard Jed Wyatt, and Robert C. Alexander. "DNA repair and mutant frequency in schizophrenia." Mutation Research/DNA Repair 255, no. 3 (1991): 241–46. http://dx.doi.org/10.1016/0921-8777(91)90027-m.

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Alexander, R. C., G. K. Magin, S. H. Robison, and R. J. Wyatt. "DNA repair and mutant frequency in schizophrenia." Schizophrenia Research 6, no. 2 (1992): 96. http://dx.doi.org/10.1016/0920-9964(92)90100-j.

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Nishimura, Kenji, Shanna K. Johansen, Takashi Inaoka, et al. "Identification of the RsmG Methyltransferase Target as 16S rRNA Nucleotide G527 and Characterization of Bacillus subtilis rsmG Mutants." Journal of Bacteriology 189, no. 16 (2007): 6068–73. http://dx.doi.org/10.1128/jb.00558-07.

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ABSTRACT The methyltransferase RsmG methylates the N7 position of nucleotide G535 in 16S rRNA of Bacillus subtilis (corresponding to G527 in Escherichia coli). Disruption of rsmG resulted in low-level resistance to streptomycin. A growth competition assay revealed that there are no differences in fitness between the rsmG mutant and parent strains under the various culture conditions examined. B. subtilis rsmG mutants emerged spontaneously at a relatively high frequency, 10−6. Importantly, in the rsmG mutant background, high-level-streptomycin-resistant rpsL (encoding ribosomal protein S12) mut
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6

Gnanamurthy, S., and D. Dhanavel. "Effect of EMS on Induced Morphological Mutants and Chromosomal Variation in Cowpea (Vigna unguiculata (L.) Walp)." International Letters of Natural Sciences 22 (August 2014): 33–43. http://dx.doi.org/10.18052/www.scipress.com/ilns.22.33.

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Effect of EMS (ethyl methane sulphonate) on induced morphological mutants and chromosomal variation in cowpea was studied using five different doses of mutagen along with a control in randomized blocked design with three replications. The morphological mutants there are two types of viable and chlorophyll mutants. Viable mutant contains tall, dwarf, early maturity, late maturity, leaf mutants pod mutant and flower mutants. The frequency of chlorophyll mutant contains albino, xantha and viridis. This concentration can damage or modify important components of plant cells and have been reported t
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7

Gnanamurthy, S., and D. Dhanavel. "Effect of EMS on Induced Morphological Mutants and Chromosomal Variation in Cowpea (<i>Vigna unguiculata</i> (L.) Walp)." International Letters of Natural Sciences 22 (August 5, 2014): 33–43. http://dx.doi.org/10.56431/p-i0xny2.

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Effect of EMS (ethyl methane sulphonate) on induced morphological mutants and chromosomal variation in cowpea was studied using five different doses of mutagen along with a control in randomized blocked design with three replications. The morphological mutants there are two types of viable and chlorophyll mutants. Viable mutant contains tall, dwarf, early maturity, late maturity, leaf mutants pod mutant and flower mutants. The frequency of chlorophyll mutant contains albino, xantha and viridis. This concentration can damage or modify important components of plant cells and have been reported t
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8

Ingham, Neil J., Navid Banafshe, Clarisse Panganiban, et al. "Inner hair cell dysfunction in Klhl18 mutant mice leads to low frequency progressive hearing loss." PLOS ONE 16, no. 10 (2021): e0258158. http://dx.doi.org/10.1371/journal.pone.0258158.

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Age-related hearing loss in humans (presbycusis) typically involves impairment of high frequency sensitivity before becoming progressively more severe at lower frequencies. Pathologies initially affecting lower frequency regions of hearing are less common. Here we describe a progressive, predominantly low-frequency recessive hearing impairment in two mutant mouse lines carrying different mutant alleles of the Klhl18 gene: a spontaneous missense mutation (Klhl18lowf) and a targeted mutation (Klhl18tm1a(KOMP)Wtsi). Both males and females were studied, and the two mutant lines showed similar phen
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9

Waddell, D. R., K. Duffy, and G. Vogel. "Cytokinesis is defective in Dictyostelium mutants with altered phagocytic recognition, adhesion, and vegetative cell cohesion properties." Journal of Cell Biology 105, no. 5 (1987): 2293–300. http://dx.doi.org/10.1083/jcb.105.5.2293.

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Mutants that have been selected for defects in phagocytic recognition, adhesion, and vegetative cell-cell cohesion were found to be larger and more highly multinucleate than their parent strain. This defect is associated with the complex mutant phenotype of these mutants since revertants of the mutants coordinately acquire the wild-type phenotype for all of the defects. The larger size and multinuclearity were due to a high frequency of failure of cytokinesis in cells of wild-type size. This was shown by purifying the small cells in mutant populations and observing their growth and cell divisi
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10

Criss, Alison K., Kevin M. Bonney, Rhoda A. Chang, Paul M. Duffin, Brian E. LeCuyer, and H. Steven Seifert. "Mismatch Correction Modulates Mutation Frequency and Pilus Phase and Antigenic Variation in Neisseria gonorrhoeae." Journal of Bacteriology 192, no. 1 (2009): 316–25. http://dx.doi.org/10.1128/jb.01228-09.

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ABSTRACT The mismatch correction (MMC) system repairs DNA mismatches and single nucleotide insertions or deletions postreplication. To test the functions of MMC in the obligate human pathogen Neisseria gonorrhoeae, homologues of the core MMC genes mutS and mutL were inactivated in strain FA1090. No mutH homologue was found in the FA1090 genome, suggesting that gonococcal MMC is not methyl directed. MMC mutants were compared to a mutant in uvrD, the helicase that functions with MMC in Escherichia coli. Inactivation of MMC or uvrD increased spontaneous resistance to rifampin and nalidixic acid,
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