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1

Martínez, Sebastián, Lukas Veth, Bruno Lainer y Paweł Dydio. "Challenges and Opportunities in Multicatalysis". ACS Catalysis 11, n.º 7 (15 de marzo de 2021): 3891–915. http://dx.doi.org/10.1021/acscatal.0c05725.

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2

Ma, Jin-Tao y Ying Cheng. "Construction of enantiopure imine bridged benzo[c]azepinones by a silver(i) and chiral N-heterocyclic carbene multicatalytic reaction sequence of N′-(2-alkynylbenzylidene)hydrazides and cyclopropanecarbaldehydes". Organic Chemistry Frontiers 7, n.º 21 (2020): 3459–67. http://dx.doi.org/10.1039/d0qo00877j.

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3

Jürjens, Gerrit, Andreas Kirschning y David A. Candito. "Lessons from the Synthetic Chemist Nature". Natural Product Reports 32, n.º 5 (2015): 723–37. http://dx.doi.org/10.1039/c4np00160e.

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Nature's strategy of performing ideal multistep (bio)synthesis are based on multicatalysis, domino reactions, iteration and compartmentation. These are discussed and compared with chemical synthesis in this conceptual review.
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4

Tang, Xinxin, Lan Gan, Xin Zhang y Zheng Huang. "n-Alkanes to n-alcohols: Formal primary C─H bond hydroxymethylation via quadruple relay catalysis". Science Advances 6, n.º 47 (noviembre de 2020): eabc6688. http://dx.doi.org/10.1126/sciadv.abc6688.

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Nature is able to synergistically combine multiple enzymes to conduct well-ordered biosynthetic transformations. Mimicking nature’s multicatalysis in vitro may give rise to new chemical transformations via interplay of numerous molecular catalysts in one pot. The direct and selective conversion of abundant n-alkanes to valuable n-alcohols is a reaction with enormous potential applicability but has remained an unreached goal. Here, we show that a quadruple relay catalysis system involving three discrete transition metal catalysts enables selective synthesis of n-alcohols via n-alkane primary C─H bond hydroxymethylation. This one-pot multicatalysis system is composed of Ir-catalyzed alkane dehydrogenation, Rh-catalyzed olefin isomerization and hydroformylation, and Ru-catalyzed aldehyde hydrogenation. This system is further applied to synthesis of α,ω-diols from simple α-olefins through terminal-selective hydroxymethylation of silyl alkanes.
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5

Sancheti, Shashank P., Urvashi, Mosami P. Shah y Nitin T. Patil. "Ternary Catalysis: A Stepping Stone toward Multicatalysis". ACS Catalysis 10, n.º 5 (8 de enero de 2020): 3462–89. http://dx.doi.org/10.1021/acscatal.9b04000.

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6

Ambrosini, Lisa M. y Tristan H. Lambert. "Multicatalysis: Advancing Synthetic Efficiency and Inspiring Discovery". ChemCatChem 2, n.º 11 (17 de septiembre de 2010): 1373–80. http://dx.doi.org/10.1002/cctc.200900323.

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7

Jindal, Garima y Raghavan B. Sunoj. "Mechanistic Insights on Cooperative Asymmetric Multicatalysis Using Chiral Counterions". Journal of Organic Chemistry 79, n.º 16 (29 de julio de 2014): 7600–7606. http://dx.doi.org/10.1021/jo501322v.

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8

Kim, Mahn-Joo, Min Young Choi, Min Young Han, Yoon Kyung Choi, Jae Kwan Lee y Jaiwook Park. "Asymmetric Transformations of Acyloxyphenyl Ketones by Enzyme−Metal Multicatalysis". Journal of Organic Chemistry 67, n.º 26 (diciembre de 2002): 9481–83. http://dx.doi.org/10.1021/jo026122m.

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9

Ambrosini, Lisa M. y Tristan H. Lambert. "ChemInform Abstract: Multicatalysis: Advancing Synthetic Efficiency and Inspiring Discovery". ChemInform 42, n.º 9 (3 de febrero de 2011): no. http://dx.doi.org/10.1002/chin.201109248.

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10

Shugrue, Christopher R., Bianca R. Sculimbrene, Elizabeth R. Jarvo, Brandon Q. Mercado y Scott J. Miller. "Outer-Sphere Control for Divergent Multicatalysis with Common Catalytic Moieties". Journal of Organic Chemistry 84, n.º 3 (4 de enero de 2019): 1664–72. http://dx.doi.org/10.1021/acs.joc.8b03068.

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11

Richmond, Edward, Ismat Ullah Khan y Joseph Moran. "Enantioselective and Regiodivergent Functionalization ofN-Allylcarbamates by Mechanistically Divergent Multicatalysis". Chemistry - A European Journal 22, n.º 35 (27 de julio de 2016): 12274–77. http://dx.doi.org/10.1002/chem.201602792.

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12

Hofmann, Christine, Sören M. M. Schuler, Raffael C. Wende y Peter R. Schreiner. "En route to multicatalysis: kinetic resolution of trans-cycloalkane-1,2-diols via oxidative esterification". Chem. Commun. 50, n.º 10 (2014): 1221–23. http://dx.doi.org/10.1039/c3cc48584f.

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We demonstrate the application of a multicatalyst to the oxidation of a broad variety of aldehydes and subsequent enantioselective esterification of the incipient acids with (±)-trans-cycloalkane-1,2-diols.
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13

Xiao, Pin, Haiyan Yuan, Jianquan Liu, Yiying Zheng, Xihe Bi y Jingping Zhang. "Radical Mechanism of Isocyanide-Alkyne Cycloaddition by Multicatalysis of Ag2CO3, Solvent, and Substrate". ACS Catalysis 5, n.º 10 (22 de septiembre de 2015): 6177–84. http://dx.doi.org/10.1021/acscatal.5b01703.

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14

Georgi, Anett, Miriam Velasco Polo, Klara Crincoli, Katrin Mackenzie y Frank-Dieter Kopinke. "Accelerated Catalytic Fenton Reaction with Traces of Iron: An Fe–Pd-Multicatalysis Approach". Environmental Science & Technology 50, n.º 11 (26 de mayo de 2016): 5882–91. http://dx.doi.org/10.1021/acs.est.6b01049.

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15

Youn, So Won, Hyoung Sub Song y Jong Hyub Park. "Asymmetric Domino Multicatalysis for the Synthesis of 3-Substituted Phthalides: Cinchonine/NHC Cooperative System". Organic Letters 16, n.º 3 (24 de enero de 2014): 1028–31. http://dx.doi.org/10.1021/ol5000617.

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16

Lorion, Mélanie M., Nikolaos Kaplaneris, Jongwoo Son, Rositha Kuniyil y Lutz Ackermann. "Late‐Stage Peptide Diversification through Cobalt‐Catalyzed C−H Activation: Sequential Multicatalysis for Stapled Peptides". Angewandte Chemie 131, n.º 6 (9 de enero de 2019): 1698–702. http://dx.doi.org/10.1002/ange.201811668.

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17

Ramachary, Dhevalapally B., Rumpa Mondal y Chintalapudi Venkaiah. "Rapid Synthesis of Functionalized Indenes, Triazoles, and Glucocorticoid Receptor Modulators by Sequential Multicatalysis Cascade Reactions". European Journal of Organic Chemistry 2010, n.º 17 (3 de mayo de 2010): 3205–10. http://dx.doi.org/10.1002/ejoc.201000220.

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18

Lorion, Mélanie M., Nikolaos Kaplaneris, Jongwoo Son, Rositha Kuniyil y Lutz Ackermann. "Late‐Stage Peptide Diversification through Cobalt‐Catalyzed C−H Activation: Sequential Multicatalysis for Stapled Peptides". Angewandte Chemie International Edition 58, n.º 6 (9 de enero de 2019): 1684–88. http://dx.doi.org/10.1002/anie.201811668.

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19

Breder, Alexander y Christian Depken. "Light‐Driven Single‐Electron Transfer Processes as an Enabling Principle in Sulfur and Selenium Multicatalysis". Angewandte Chemie International Edition 58, n.º 48 (25 de noviembre de 2019): 17130–47. http://dx.doi.org/10.1002/anie.201812486.

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20

Jin, Zhichao, Jianfeng Xu, Song Yang, Bao-An Song y Yonggui Robin Chi. "Enantioselective Sulfonation of Enones with Sulfonyl Imines by Cooperative N-Heterocyclic-Carbene/Thiourea/Tertiary-Amine Multicatalysis". Angewandte Chemie 125, n.º 47 (2 de octubre de 2013): 12580–84. http://dx.doi.org/10.1002/ange.201305023.

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21

Hofmann, Christine, Soeren M. M. Schuler, Raffael C. Wende y Peter R. Schreiner. "ChemInform Abstract: En route to Multicatalysis: Kinetic Resolution of trans-Cycloalkane-1,2-diols via Oxidative Esterification." ChemInform 45, n.º 22 (15 de mayo de 2014): no. http://dx.doi.org/10.1002/chin.201422067.

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22

Youn, So Won, Hyoung Sub Song y Jong Hyub Park. "ChemInform Abstract: Asymmetric Domino Multicatalysis for the Synthesis of 3-Substituted Phthalides: Cinchonine/NHC Cooperative System." ChemInform 45, n.º 29 (3 de julio de 2014): no. http://dx.doi.org/10.1002/chin.201429125.

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23

Jin, Zhichao, Jianfeng Xu, Song Yang, Bao-An Song y Yonggui Robin Chi. "Enantioselective Sulfonation of Enones with Sulfonyl Imines by Cooperative N-Heterocyclic-Carbene/Thiourea/Tertiary-Amine Multicatalysis". Angewandte Chemie International Edition 52, n.º 47 (2 de octubre de 2013): 12354–58. http://dx.doi.org/10.1002/anie.201305023.

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24

Ramachary, Dhevalapally B., Rumpa Mondal y Chintalapudi Venkaiah. "ChemInform Abstract: Rapid Synthesis of Functionalized Indenes, Triazoles, and Glucocorticoid Receptor Modulators by Sequential Multicatalysis Cascade Reactions." ChemInform 41, n.º 44 (7 de octubre de 2010): no. http://dx.doi.org/10.1002/chin.201044036.

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25

Liu, Jiahui, Yiying Zheng, Ying Liu, Haiyan Yuan y Jingping Zhang. "Mechanistic insight on (E )-methyl 3-(2-aminophenyl)acrylate cyclization reaction by multicatalysis of solvent and substrate". Journal of Computational Chemistry 37, n.º 26 (4 de agosto de 2016): 2386–94. http://dx.doi.org/10.1002/jcc.24463.

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26

Jin, Zhichao, Jianfeng Xu, Song Yang, Bao-An Song y Yonggui Robin Chi. "ChemInform Abstract: Enantioselective Sulfonation of Enones with Sulfonyl Imines by Cooperative N-Heterocyclic-Carbene/Thiourea/Tertiary-Amine Multicatalysis." ChemInform 45, n.º 14 (21 de marzo de 2014): no. http://dx.doi.org/10.1002/chin.201414093.

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27

Paul, Jérôme, Tania Xavier, Marc Presset, Erwan Le Gall, Eric Léonel, Christophe Pichon y Sylvie Condon. "Cobalt-Zinc-Diimine Multicatalysis: Enhanced syn Diastereoselectivity in the Reductive Multicomponent Coupling of Aryl Bromides, Acrylates and Aldehydes". ChemistrySelect 3, n.º 47 (18 de diciembre de 2018): 13480–86. http://dx.doi.org/10.1002/slct.201803710.

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28

Sanchez Díaz-Marta, Antonio, Susana Yáñez, Carmen R. Tubío, V. Laura Barrio, Yolanda Piñeiro, Rosa Pedrido, José Rivas, Manuel Amorín, Francisco Guitián y Alberto Coelho. "Multicatalysis Combining 3D-Printed Devices and Magnetic Nanoparticles in One-Pot Reactions: Steps Forward in Compartmentation and Recyclability of Catalysts". ACS Applied Materials & Interfaces 11, n.º 28 (21 de junio de 2019): 25283–94. http://dx.doi.org/10.1021/acsami.9b08119.

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29

Júnior, Aldo Araújo da Trindade, Yan Ferraz Ximenes Ladeira, Alexandre da Silva França, Rodrigo Octavio Mendonça Alves de Souza, Adolfo Henrique Moraes, Robert Wojcieszak, Ivaldo Itabaiana Jr. y Amanda Silva de Miranda. "Multicatalytic Hybrid Materials for Biocatalytic and Chemoenzymatic Cascades—Strategies for Multicatalyst (Enzyme) Co-Immobilization". Catalysts 11, n.º 8 (31 de julio de 2021): 936. http://dx.doi.org/10.3390/catal11080936.

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During recent decades, the use of enzymes or chemoenzymatic cascades for organic chemistry has gained much importance in fundamental and industrial research. Moreover, several enzymatic and chemoenzymatic reactions have also served in green and sustainable manufacturing processes especially in fine chemicals, pharmaceutical, and flavor/fragrance industries. Unfortunately, only a few processes have been applied at industrial scale because of the low stabilities of enzymes along with the problematic processes of their recovery and reuse. Immobilization and co-immobilization offer an ideal solution to these problems. This review gives an overview of all the pathways for enzyme immobilization and their use in integrated enzymatic and chemoenzymatic processes in cascade or in a one-pot concomitant execution. We place emphasis on the factors that must be considered to understand the process of immobilization. A better understanding of this fundamental process is an essential tool not only in the choice of the best route of immobilization but also in the understanding of their catalytic activity.
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30

Sakthivel, Shanmugam y Rengarajan Balamurugan. "Annulation of a Highly Functionalized Diazo Building Block with Indoles under Sc(OTf)3/Rh2(OAc)4 Multicatalysis through Michael Addition/Cyclization Sequence". Journal of Organic Chemistry 83, n.º 19 (4 de septiembre de 2018): 12171–83. http://dx.doi.org/10.1021/acs.joc.8b02127.

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31

Ramachary, Dhevalapally B., Kinthada Ramakumar, Adluri Bharanishashank y Vidadala V. Narayana. "Sequential One-Pot Combination of Multireactions through Multicatalysis: A General Approach to Rapid Assembly of Functionalized Push−Pull Olefins, Phenols, and 2-Methyl-2H-chromenes". Journal of Combinatorial Chemistry 12, n.º 6 (8 de noviembre de 2010): 855–76. http://dx.doi.org/10.1021/cc100104k.

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32

Mata, José A., F. Ekkehardt Hahn y Eduardo Peris. "Heterometallic complexes, tandem catalysis and catalytic cooperativity". Chem. Sci. 5, n.º 5 (2014): 1723–32. http://dx.doi.org/10.1039/c3sc53126k.

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33

Gaur, Akshay, Chirag Porwal, Imed Boukhris, Vishal Singh Chauhan y Rahul Vaish. "Review on Multicatalytic Behavior of Ba0.85Ca0.15Ti0.9Zr0.1O3 Ceramic". Materials 16, n.º 16 (21 de agosto de 2023): 5710. http://dx.doi.org/10.3390/ma16165710.

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Ferroelectric materials are known to possess multicatalytic abilities that are nowadays utilized for removing organic pollutants from water via piezocatalysis, photocatalysis, piezo-photocatalysis, and pyrocatalysis processes. The Ba0.85Ca0.15Ti0.9Zr0.1O3 (BCZTO) ceramic is one such ferroelectric composition that has been extensively studied for electrical and electronic applications. Furthermore, the BCZTO ceramic has also shown remarkable multicatalytic performance in water-cleaning applications. The present review explores the potentiality of BCZTO for water-cleaning and bacterial-killing applications. It also highlights the fundamentals of ferroelectric ceramics, the importance of electric poling, and the principles underlying piezocatalysis, photocatalysis, and pyrocatalysis processes in addition to the multicatalytic capability of ferroelectric BCZTO ceramic.
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34

Arribas, J., M. Luz Rodríguez, R. Alvarez-Do Forno y J. G. Castaño. "Autoantibodies against the multicatalytic proteinase in patients with systemic lupus erythematosus." Journal of Experimental Medicine 173, n.º 2 (1 de febrero de 1991): 423–27. http://dx.doi.org/10.1084/jem.173.2.423.

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Sera from patients with systemic lupus erythematosus contain specific autoantibodies directed against different polypeptide components of the multicatalytic proteinase (also known as proteasome or prosome). These human autoantibodies, in contrast to polyclonal antibodies obtained in rabbits against the purified enzyme, recognize highly conserved epitopes of the multicatalytic proteinase polypeptides from yeast to human.
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35

Rivett, A. J. "The Multicatalytic Proteinase". Journal of Biological Chemistry 264, n.º 21 (julio de 1989): 12215–19. http://dx.doi.org/10.1016/s0021-9258(18)63843-8.

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36

Nelson, Judith E., Claudia Altschuller-Felberg, Anna Loukissa y Christopher Cardozo. "Proteasome from cytokine-treated human cells shows stimulated BrAAP activity and depressed PGPH activity". Biochemistry and Cell Biology 78, n.º 2 (1 de abril de 2000): 115–18. http://dx.doi.org/10.1139/o00-006.

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The branched chain amino acid-preferring (BrAAP) activity of multicatalytic proteinase complex isolated from human umbilical vein endothelial cells and treated with interferon-gamma was increased more than 2-fold, which was associated with a marked increase in LMP7 expression and decreased peptidylglutamyl peptide-hydrolyzing activity. Increases in BrAAP activity in supernatants from cells treated with interferon-gamma, tumor necrosis factor-alpha, interleukin-1beta, interleukin-6, or lipopolysaccharide paralleled the increases in LMP7 expression. These findings are consistent with the conclusion that the increased BrAAP activity of LMP-containing multicatalytic proteinase complex results from incorporation of LMP7 or other LMP subunits.
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37

Rivett, A. J. "Proteasomes: multicatalytic proteinase complexes". Biochemical Journal 291, n.º 1 (1 de abril de 1993): 1–10. http://dx.doi.org/10.1042/bj2910001.

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38

Ho, Xuan-Huong, Won-Ji Jung, Pranab K. Shyam y Hye-Young Jang. "Copper–dienamine catalysis: γ-oxyamination of α,β-unsaturated aldehydes". Catal. Sci. Technol. 4, n.º 7 (2014): 1914–19. http://dx.doi.org/10.1039/c4cy00271g.

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39

Poe, Sarah L., Muris Kobašlija y D. Tyler McQuade. "Microcapsule Enabled Multicatalyst System". Journal of the American Chemical Society 128, n.º 49 (diciembre de 2006): 15586–87. http://dx.doi.org/10.1021/ja066476l.

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40

Zhang, Xiao-Qian, Xue-Jiao Lv, Jun-Ping Pei, Rui Tan y Yan-Kai Liu. "An asymmetric multicatalytic reaction sequence of 2-hydroxycinnamaldehydes and enolic 1,3-dicarbonyl compounds to construct bridged bicyclic acetals". Organic Chemistry Frontiers 7, n.º 2 (2020): 292–97. http://dx.doi.org/10.1039/c9qo01272a.

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2-Hydroxycinnamaldehydes and cyclic 1,3-dicarbonyl nucleophiles were used in an asymmetric organocatalyzed reaction sequence to construct bridged bicyclic acetals via a multicatalytic process involving iminium catalysis and anion-binding catalysis.
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41

Wagner, B. J., Joyce W. Margolis y Inderpal Singh. "Bovine Lens Multicatalytic Proteinase Complex". Enzyme and Protein 47, n.º 4-6 (1993): 202–9. http://dx.doi.org/10.1159/000468679.

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42

Folco, Eduardo J., Liliana Busconi, Celina B. Martone y Jorge J. Sanchez. "Multicatalytic proteinase in fish muscle". Archives of Biochemistry and Biophysics 267, n.º 2 (diciembre de 1988): 599–605. http://dx.doi.org/10.1016/0003-9861(88)90067-7.

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43

S�nchez, Jorge J., Eduardo J. Folco, Liliana Busconi, Celina B. Martone, Claudia Studdert y Claudia A. Casalongu�. "Multicatalytic proteinase in fish muscle". Molecular Biology Reports 21, n.º 1 (1995): 63–69. http://dx.doi.org/10.1007/bf00990973.

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44

SAVORY, PETER J. y A. JENNIFER RIVETT. "Catalytic subunits of the multicatalytic proteinase". Biochemical Society Transactions 19, n.º 3 (1 de agosto de 1991): 292S. http://dx.doi.org/10.1042/bst019292s.

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45

ELLISON, DEREK S., JOHN HINTON y ROBERT J. BEYNON. "Construction of an artificial ‘multicatalytic protease’". Biochemical Society Transactions 21, n.º 1 (1 de febrero de 1993): 33S. http://dx.doi.org/10.1042/bst021033s.

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46

NOTHWANG, Hans-Gred, Oliver COUX, Faycal BEY y Klaus SCHERRER. "Prosomes and their multicatalytic proteinase activity". European Journal of Biochemistry 207, n.º 2 (julio de 1992): 621–30. http://dx.doi.org/10.1111/j.1432-1033.1992.tb17089.x.

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47

Eleuteri, Anna Maria, Ronald A. Kohanski, Christopher Cardozo y Marian Orlowski. "Bovine Spleen Multicatalytic Proteinase Complex (Proteasome)". Journal of Biological Chemistry 272, n.º 18 (2 de mayo de 1997): 11824–31. http://dx.doi.org/10.1074/jbc.272.18.11824.

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48

Zein, Haggag S., Jaime A. Teixeira da Silva y Kazutaka Miyatake. "Molecular analysis of multicatalytic monoclonal antibodies". Molecular Immunology 47, n.º 9 (mayo de 2010): 1747–56. http://dx.doi.org/10.1016/j.molimm.2010.02.024.

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49

Rechsteiner, M., L. Hoffman y W. Dubiel. "The multicatalytic and 26 S proteases." Journal of Biological Chemistry 268, n.º 9 (marzo de 1993): 6065–68. http://dx.doi.org/10.1016/s0021-9258(18)53218-x.

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50

SWEENEY, SEAN T. y A. JENNIFER RIVETT. "Immunological properties of the multicatalytic proteinase". Biochemical Society Transactions 17, n.º 6 (1 de diciembre de 1989): 1126–27. http://dx.doi.org/10.1042/bst0171126.

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