Literatura académica sobre el tema "Modèle intestinal in vitro"
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Artículos de revistas sobre el tema "Modèle intestinal in vitro":
Uriot, O., C. Deschamps, M. Brun, M. Pouget, L. Etienne-Mesmin, M. Alric, C. Chaudemanche, Y. Boirie y S. Blanquet-Diot. "Développement et validation d’un modèle colique in vitro de dysbiose du microbiote intestinal humain associé à l’obésité". Nutrition Clinique et Métabolisme 37, n.º 2 (mayo de 2023): e20. http://dx.doi.org/10.1016/j.nupar.2023.03.032.
Amamou, A., L. Yaker, C. Bôle-Feysot, G. Savoye y R. Marion-Letellier. "Étude de l’interaction entre des dérivés du tryptophane et le récepteur aryl hydrocarbone dans un modèle in vitro de fibrose intestinale". Nutrition Clinique et Métabolisme 33, n.º 1 (marzo de 2019): 100. http://dx.doi.org/10.1016/j.nupar.2019.01.412.
Vergères, Guy, Biljana Bogicevic, Caroline Buri, Sandro Carrara, Magali Chollet, Linda Corbino-Giunta, Lotti Egger et al. "The NutriChip project – translating technology into nutritional knowledge". British Journal of Nutrition 108, n.º 5 (11 de julio de 2012): 762–68. http://dx.doi.org/10.1017/s0007114512002693.
Jackson, Tim R., Miniver Oliver, Daniel Appledorn, Tim Dale y Kalpana Barnes. "Abstract 3084: Label-free, real-time live cell assays for 3D organoids embedded in Matrigel®". Cancer Research 82, n.º 12_Supplement (15 de junio de 2022): 3084. http://dx.doi.org/10.1158/1538-7445.am2022-3084.
Losa, Marco, Michael Field, Lauren Collen, Jared Barends, Amit Ringel, Mairead Bresnahan, Jessica Yang et al. "BIOACTIVE INTERLEUKIN-1 DETECTED IN IBD PATIENT INTESTINAL BIOPSIES IS A HALLMARK OF ULCERS AND CORRELATES WITH TRANSCRIPTOMIC ASSESSMENTS, INCLUDING AN ULCER-ASSOCIATED GENE MODULE". Inflammatory Bowel Diseases 30, Supplement_1 (25 de enero de 2024): S00. http://dx.doi.org/10.1093/ibd/izae020.117.
Rashid, Md Harun Or y Feng Lin. "Magnetically Driven Biopsy Capsule Robot with Spring Mechanism". Micromachines 15, n.º 2 (18 de febrero de 2024): 287. http://dx.doi.org/10.3390/mi15020287.
Dupont, C., M. E. Bougnoux, J. Matéo, P. Saulnier, D. Payen y M. H. Nicolas-Chanoine. "Diagnostic des candidoses profondes par PCR modèle in vitro et modèle animal". La Revue de Médecine Interne 17 (enero de 1996): 356s. http://dx.doi.org/10.1016/s0248-8663(97)80878-8.
Dupont, C., M. E. Bougnoux, J. Mateo, P. Saulnier, D. Payen y M. H. Nicolas-Chanoine. "Diagnostic des candidoses profondes par PCR. Modèle in vitro et modèle animal". Médecine et Maladies Infectieuses 27 (noviembre de 1997): 1005. http://dx.doi.org/10.1016/s0399-077x(97)80272-7.
Durix, A., L. Alves de Oliveira, S. Komizarczuck-Bony, M. Carcelen y C. Jean-Blain. "Caractéristiques fermentaires d'un modèle d'acidose in vitro (RUSITEC)". Annales de Zootechnie 43, Suppl. 1 (1994): 26s. http://dx.doi.org/10.1051/animres:19940530.
Breton, J., P. Tirelle, S. Hasanat, A. Pernot, C. L’Huillier, J. C. do Rego, P. Déchelotte, M. Coëffier, L. B. Bindels y D. Ribet. "Altérations du microbiote intestinal dans un modèle murin d’Anorexie mentale". Nutrition Clinique et Métabolisme 34, n.º 1 (abril de 2020): 37–38. http://dx.doi.org/10.1016/j.nupar.2020.02.238.
Tesis sobre el tema "Modèle intestinal in vitro":
Ponce, de Leon Rodriguez Maria del Carmen. "Développement d’un modèle in vitro d’inflammation intestinale par l’utilisation de lignées cellulaires humaines en co-culture pour l’étude des interactionsavec les micro-constituants alimentaires". Thesis, Montpellier, 2019. http://www.theses.fr/2019MONTG009/document.
The intestinal epithelium, main place of the absorption of (micro)-nutrients is also the first body's defense system. An imbalance in homeostasis can lead to an inflammatory reaction associated with defects in the intestinal barrier and immune function as well as malabsorption of nutrients, as seen in IBD (Inflammatory Bowel Diseases), in micronutrient fortification strategies and noncommunicable diseases (obesity). It is therefore important to find ways of action, for example through diet, to prevent or at least reduce the nutritional and pathological consequences of intestinal inflammation, and to understand the mechanisms involved. Among intestinal models, in vitro cell culture models are increasingly used and allow to evaluate the molecular mechanisms in a simple and reproducible way and to reduce animal experimentation.In this context and in order to study the interaction of dietary bioactive compounds with the intestine in state of inflammation, the first objective of this work was the development of an in vitro model of inflamed intestine combining in co-culture two human intestinal cell lines: Caco-2 TC7 (enterocytes) and HT29-MTX (goblet cells) and an immune cell line of macrophages (THP1). Several inflammation markers were evaluated and we were able to show that the tri-culture model responded to an inflammatory stimulus (LPS / IFNγ), by increasing the production of pro-inflammatory cytokines (TNF-α, IL6 and IL8) and enzymes (INOS and COX2) as well as the expression of their genes. In addition, an increase of epithelial permeability via tight junctions (TJs) alteration has also been demonstrated, as well as overproduction of mucus, which are recognized inflammation characteristics.The second objective was to study the interaction of β-cryptoxanthin (BCX), a lipophilic and antioxidant carotenoid of citrus, with the inflamed model. To solubilize BCX, we used two types of micelles (artificial and physiological) and studied markers of inflammation. Although it appears from the preliminary results that BCX micelles show a tendency to decrease the production of some cytokines (IL6 and IL8), the role of micelle constituents (Tween 40 or bile salts / phospholipids) in the phenomenon observed and in the epithelial permeability remains to be therefore clarified
Roy, Isabelle. "Contribution à la mise en place d'un modèle "in vitro" prédictif de l'absorption et du métabolisme intestinal". Paris 5, 1994. http://www.theses.fr/1994PA05P159.
Fleury, Mickaël. "Impact de traitements antibiotiques sur la flore digestive du porcelet : Etude in vivo et développement d'une approche en système de fermentation in vitro". Thesis, Rennes 1, 2015. http://www.theses.fr/2015REN1B002/document.
In the context of antibiotic resistance, the aim of the current PhD work is to assess the impact of antibiotics on intestinal microbiota of piglets. Two antibiotics i.e. colistin and ceftiofur, for which the main resistances include respectively chromosomal mutations and plasmid genes have been used. Colistin significantly reduced the population of Enterobacteriaceae, but there was no selection of resistant E. coli. The administration of ceftiofur had a limited impact on the bacterial populations that make up the digestive ecosystem but it led to strong selection and dissemination of a plasmid gene encoding an extended-spectrum beta-lactamase. Then, in the framework of regulations to reduce animal testing, an in vitro model of colonic pig named PigutIVM was developed in order to simulate the digestive environment of the piglet and then check the effect of colistin on the microbiota simulated in PigutIVM in vitro. Therefore both the approaches i.e. in vivo and in vitro were compared in order to check the effect of colistin on intestinal microbiota of piglets. This tool was then used to evaluate the impact of a probiotic i.e. Saccharomyces cerevisiae, as alternative to antibiotics. Therefore we assume that this PigutIVM model should be positioned as a relevant predictive tool in the fields of nutritional and pharmacological investigations
Altay, Gizem. "Towards the development of biomimetic in vitro models of intestinal epithelium derived from intestinal organoids". Doctoral thesis, Universitat de Barcelona, 2018. http://hdl.handle.net/10803/664864.
El epitelio intestinal es un tejido altamente especializado, organizado en unidades de criptas y vellosidades que son relevantes para sus eficaces funciones de barrera y absorción de nutrientes. En las unidades de criptas residen las células madre intestinales (ISC) proliferativas que se dividen y diferencian mientras migran a lo largo de las vellosidades, las cuales generan el epitelio maduro. En el epitelio maduro, las ISC y las células proliferativas se localizan en las criptas y las células absorbentes y secretoras diferenciadas en las vellosidades. La proliferación, migración y diferenciación de las ISC se rigen por los gradientes químicos espaciales altamente controlados de los factores de nicho de la ISC; Moduladores de la vía de bone morphogenic protein (BMP), wingless/Int (Wnt) y epidermal growth factor (EGF). El modelado experimental de la biología y la fisiología del epitelio intestinal está limitado debido a la falta de plataformas in vitro que recapitulan estos aspectos clave del epitelio del intestino delgado: sus distintas poblaciones celulares, la arquitectura 3D y los gradientes de factores bioquímicos de nicho ISC a lo largo del eje cripta-vellosidad. Aquí, describimos el desarrollo de modelos in vitro de epitelio intestinal obtenidos de criptas derivadas de organoides intestinales. En primer lugar, presentamos un método para obtener monocapas epiteliales intestinales 2D con lumen accesible y función de barrera fisiológica. A continuación, describimos el desarrollo de andamios biomiméticos 3D similares a vellosidades en hidrogeles de diacrilato de polietilenglicol (PEGDA) utilizando un enfoque fotolitográfico simple y rentable. Demostramos que nuestra plataforma de vellosidades sintéticas apoya la formación de monocapas epiteliales de células epiteliales intestinales derivadas de organoides. Finalmente, describimos métodos para crear gradientes espaciotemporales de factores nicho bioquímicos ISC en hidrogeles 3D similares a vellosidades y demostramos que estos gradientes se pueden usar para compartimentar las células epiteliales diferenciadas. La plataforma 3D que recrea las vellosidades intestinalesmejora los modelos actuales al proporcionar a las células las señales topográficas y mecánicas y los gradientes bioquímicos fisiológicamente representativos. Debido a su utilidad, esta plataforma puede encontrar innumerables aplicaciones. Puede ser utilizada para la comprensión de la biología básica del epitelio intestinal. Además, se puede utilizar para cultivar células madre intestinales humanas que permitan la detección de nuevas terapias y el modelado de enfermedades.
Gérémie, Lauriane. "Development of an in-vitro intestinal model featuring peristaltic motion". Thesis, Sorbonne université, 2019. http://accesdistant.sorbonne-universite.fr/login?url=http://theses-intra.upmc.fr/modules/resources/download/theses/2019SORUS118.pdf.
My PhD work is part of the organ-on-chip field, and more precisely part of the gut-on-chip field. It is in line with the main objective of this field, which is the development of in-vitro models recapitulating as faithfully as possible the intestinal micro-environment. Through my PhD work I first developed a versatile gut-on-chip platform recapitulating the intestinal 3D architecture as well as its dynamic micro-environment. Therefore, this platform allows us to study the influence of the intestinal dynamic, especially the peristalsis, on cellular behavior in function of the 3D architecture of the scaffold. For this study Caco2 cells have been seeded either on a 2D or a 3D scaffold coated with laminin and submitted to a cyclic stretching (at 0.2 Hz and 10%) for 2, 5, 8, 16, 24 and 48 hours. Our main observation was the cellular reorientation induced by the stretching, therefore we characterized the cell behavior in function of the coating condition, the initial confluency, the stretching time and the scaffold geometry. Interestingly, the strongest cellular response was obtained when the 3D geometry and the stretching was combined illustrating the need of these two stimuli to better mimic the intestinal in vivo conditions
Garcia, Rodriguez Alba. "The applicability of in vitro models of the intestinal barrier for the risk assessment of engineered nanomaterials used as food additives". Doctoral thesis, Universitat Autònoma de Barcelona, 2018. http://hdl.handle.net/10803/669883.
Nano-technological approaches are allowing the development of deliberately engineered nanomaterials (ENMs), presenting promising new applications for many industrial fields. Especially, ENMs possess unique properties and novel uses in food or food packaging materials such as the enhancement of texture, colour, flavour, nutrient stability and food packaging safety. Despite their innovative properties, there is an increasing concern about the possibility that human exposure to TiO2NPs may lead to significant adverse health effects. The International Agency for Research on Cancer (IARC) classified TiO2 as a human carcinogen group 2B because there was enough evidence that nano-TiO2 may cause lung cancer by inhalation. Although oral exposure was also debated by IARC, the final report was inconclusive due to non-existing standardized procedures for nano- TiO2 risk assessment. Due to the potential adverse effects of this ENMs and the lack of information regarding toxicological aspects over the oral exposure, in this Thesis we have carried out in vitro studies on the biological effects of TiO2NPs. For the aforementioned purpose, we set up and characterized, for the first time in our laboratory, an epithelial in vitro model that closely mimics the human small intestine. Thus, in our first study, we defined the best culture conditions for the alreadydescribed model, Caco-2/HT29/Raji-B. From our integrity and permeability findings, we confirmed that the best Caco-2/HT29 cell ratio is 90:10, respectively, as TEER values, paracellular LY permeability and the mucus shed formed correlated well with other studies. We also were able to detect the induction of M-like cells by TEM. Moreover, in order to monitor the proper barrier formation, we proposed a set of genes related to the cell junctional complexes, brush border enzymes, mucus shed components and M-cell markers. Finally, we tested the goodness of our epithelial in vitro model by exposing it to both TiO2NPs and SiO2NPs for 24 h. Our confocal results evidenced the potential adverse effects of TiO2NPs and SiO2NPs on the intestinal epithelium, as NPs internalization and NPs-cell nucleus interaction were observed. Because of the heightened interest in the identification, validation and standardization of the effects associated to exposures to new ENMs, our second study aimed to assess the effects of three different shapes of TiO2NPs (spheres, rods and wires) on the Caco-2/HT29 barrier. Our results demonstrated that the three types of TiO2NPs have the ability to impair the membrane’s integrity, translocate through the mucus shed and internalize in the cells, reaching the nucleus. Taking into account our confocal images results, we hypothesize that due to their shapes, nano-wires are more likely to cross paracellularly, while nano-spheres and nano-rods used intracellular passage to cross the intestinal epithelium. Despite previous evidence that relate the capability of TiO2NPs to produce ROS, we have not detected oxidatively DNA damage. However, and in accordance with the confocal images showing a great amount of NPscell nucleus events, we detected a slight but significant general DNA damage in the barrier’s cells. Finally, the third study was performed under the framework of an international mention carried out in the Biomedical Engineering Department at the Binghamton University (Binghamton, NY, USA). Nutrient absorption is one of the main and most important functions of the small intestine. Thus, to understand and evaluate whether ENPs can trigger physiological potential pathologies, the activity of the intestinal alkaline phosphatase (IAP), aminopeptidase-N (APN) and Na+/K+ ATPase enzymes were measured after exposing the Caco-2/HT29-MTX barrier to TiO2NPs and SiO2NPs for 4 h. Moreover, and in order to further mimic the physiological conditions of a real digestion, the Caco-2/HT29-MTX barrier was exposed to both NPs previously digested and co-cultured with both Escherichia coli and Lactobacillus rhamnosus, as examples of commensal microbiota.
SUNDARAM, TAMIL SELVI. "ESTABLISHING IN VITRO INTESTINAL EPITHELIAL CELL MODELS IN TRANSLATIONAL ANIMAL NUTRITION". Doctoral thesis, Università degli Studi di Milano, 2022. https://hdl.handle.net/2434/944348.
Kratz, Jadel Müller. "Implementação e aplicação do modelo in vitro com células Caco-2 para estudo da permeabilidade intestinal de fármacos". Florianópolis, SC, 2011. http://repositorio.ufsc.br/xmlui/handle/123456789/95611.
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A absorção oral de um fármaco é controlada fundamentalmente por dois fatores: a solubilidade aquosa/dissolução e a permeabilidade intestinal. Portanto, a determinação dessas características ainda nas fases de descoberta e desenvolvimento de fármacos pode prover moléculas com ótimo perfil biofarmacêutico. Nesse sentido, esta tese teve dois objetivos: implementar e validar o modelo de avaliação da permeabilidade in vitro com células Caco-2 no Laboratório de Virologia Aplicada da UFSC, e aplicar esse modelo na determinação da permeabilidade de fármacos e compostos em estudo. Na implementação do modelo Caco-2 foi demonstrada a adequação morfológica das células, através do monitoramento da resistência elétrica transepitelial e da permeabilidade do Lucifer yellow. Através da avaliação da permeabilidade de fármacos marcadores (aciclovir, carbamazepina, hidroclorotiazida, propranolol, vimblastina e verapamil) em experimentos de transporte bi-direcional foi demonstrado que o modelo foi devidamente validado, já que foi estabelecida correlação entre a permeabilidade in vitro e a absorção em humanos. Adicionalmente, uma metodologia por CLAE-UV foi desenvolvida e validada para a determinação concomitante de todos esses fármacos marcadores. Na segunda etapa, avaliou-se o complexo talidomida:hidroxipropil-?-ciclodextrina, desenvolvido e caracterizado no estado sólido por diferentes técnicas, que comprovaram a complexação do fármaco e a redução da sua cristalinidade. Essas alterações culminaram em um leve aumento da solubilidade aparente do fármaco, bem como propiciaram um perfil de dissolução superior, quando comparado ao da talidomida isolada. No entanto, nenhuma alteração na permeabilidade foi detectada. Esses resultados sugerem que esta complexação poderia aumentar a biodisponibilidade oral da talidomida, através do aumento da sua solubilidade nos fluídos gastrointestinais, bem como facilitando a sua dissolução a partir de uma forma farmacêutica sólida. Também foi avaliado o composto anti-herpético galato de pentila, e foi demonstrado que ele apresenta perfis de permeabilidade intestinal e cutânea favoráveis para sua absorção oral e permeação tópica, respectivamente. Assim, após administração oral, sua biodisponibilidade não seria limitada pela permeabilidade intestinal, e no que se refere à administração tópica, ele ficaria restrito às camadas da pele no local de aplicação. Esses dados fornecem informações valiosas para o desenvolvimento de formas farmacêuticas e para a avaliação da atividade antiviral in vivo. Em suma, o modelo com células Caco-2 foi implementado, validado e aplicado satisfatoriamente, o que permitirá a execução de estudos colaborativos, sobretudo com o enfoque do Sistema de Classificação Biofarmacêutica.
Langan, Laura. "Fish intestinal cultures for ecotoxicological studies : in vitro and primary culture models". Thesis, University of Plymouth, 2017. http://hdl.handle.net/10026.1/9486.
Deschamps, Charlotte. "Impact du poids corporel et d'une perturbation antibiotique sur le microbiote intestinal du chien : simulation in vitro et stratégies de restauration". Electronic Thesis or Diss., Université Clermont Auvergne (2021-...), 2023. http://www.theses.fr/2023UCFA0055.
Different dog sizes are associated with variations in digestive physiology, mainly related to the large intestine and its resident microorganisms. This gut microbiota plays a key role in animal health, supporting nutritional, immunological and physiological processes. Nevertheless, diseases or antibiotherapy can disturb microbial equilibrium and induce a perturbated state called dysbiosis. To restore microbiota eubiosis, new restorations strategies have been developed such as pre-, pro- or postbiotics. However, very few studies have evaluated their effects on gut microbiota in the context of antibiotherapy. This joint PhD between the Microbiology, Digestive Environment and Health unit from Université Clermont Auvergne and the two compagnies Lallemand Animal Nutrition and Dômes Pharma, aimed to investigate the impact of body weight and antibiotic disturbance on canine colonic microbiota, as well as the potential of microbial restoration strategies, using in vitro gut models.This thesis started by evaluating the impact of different methods for faecal sample storage (48-h freezing -80°C, 48-h -80°C with glycerol or lyophilization with maltodextrin/trehalose) on the kinetics of microbiota colonization and metabolic activities in the Mucosal Artificial Colon (M-ARCOL). Compared to fresh stools, inoculating with raw frozen stool without cryoprotectant was the best option among those tested. Second, thanks to a large literature review, the M-ARCOL model was adapted to reproduce the main nutritional, physicochemical and microbial parameters specific from small, medium and large size conditions in a new model called Canine M-ARCOL (CANIM-ARCOL), further validated through in vitro-in vivo comparisons. This adaptation allowed to reproduce in vitro the increase in Bacteroidota and Firmicutes abundances and higher main short-chain fatty acid (SCFA) concentrations observed in vivo. Then, we used the CANIM-ARCOL to perform a mechanistic study, which revealed that nutritional and physicochemical parameters are enough to shape microbiota activity according to dog size, but faecal inoculum was necessary to reproduce size-related microbiota composition. The next step was to adapt the CANIM-ARCOL to diseased situation, focusing on antibiotic-induced dysbiosis. In accordance with in vivo data, antibiotherapy induced an increase in Enterobacteriaceae, Streptococcaceae and Lactobacillaceae relative abundances while alpha-diversity and SCFA production decreased. Similar but lower effects were observed in mucus-associated microbiota. Lastly, we evaluated the effect of the live probiotic yeast Saccharomyces boulardii CNCM I-1079 and the heat-inactivated bacteria Lactobacillus helveticus HA-122 on microbiota resistance during antibiotic treatment and resilience afterwards. Of interest, both microbial strategies decreased the Enterobacteriaceae bloom during antibiotherapy and allowed, in the first two days, a quicker recovery of microbiota composition and activity, in both the luminal and mucosal compartments.This PhD work provided pioneering and significant insights into the impact of dog size and antibiotherapy on canine colonic luminal and mucus-associated microbiota composition and activity, filling gaps in knowledge in these fields. This work also contributed to a better understanding of microbiota resilience in response to antibiotic disturbance. In a near future, in accordance with the European 3R's rules aiming to reduce at a maximum animal experiments, our in vitro approaches could be used for mechanistic studies on the interactions between nutrients, feed additives or veterinary products and canine colonic microbiota. Such experiments could be performed under healthy but also disturbed gut microbial situations (including obesity, inflammatory bowel diseases or chronic enteropathies), always considering interindividual variabilities to move towards personalized nutrition and medicine
Libros sobre el tema "Modèle intestinal in vitro":
Mahmood, Belal A. I. Studies on the effects of cholera toxin and fish oil on intestinal secretion in vitro. Manchester: University of Manchester, 1994.
Nicklin, Paul Leslie. Amino acid, peptide and drug transport across monolayers of human intestinal (CAC0-2) cells in vitro. Birmingham: Aston University. Department of Pharmaceutical Sciences., 1993.
Essai n° 431 : Corrosion Cutanée In Vitro : Essai sur Modèle de Peau Humaine. OECD, 2014. http://dx.doi.org/10.1787/9789264224216-fr.
Essai n° 431 : Corrosion cutanée in vitro : Essai sur modèle de peau humaine. OECD, 2019. http://dx.doi.org/10.1787/9789264264625-fr.
Essai n° 431: Corrosion cutanée in vitro :Essai sur modèle de peau humaine. OECD, 2004. http://dx.doi.org/10.1787/9789264071155-fr.
Essai n° 431 : Corrosion cutanée in vitro : Essai sur modèle de peau humaine. OECD, 2015. http://dx.doi.org/10.1787/9789264242784-fr.
Essai n° 431 : Corrosion cutanée in vitro : Essai sur modèle de peau humaine. OECD, 2013. http://dx.doi.org/10.1787/9789264203839-fr.
H.R. Hemati Matin, F. Shariatmadari*, M.A. Karimi Torshizi y L.I. Chiba. Effect of dietary fibre sources on in vitro mineral binding capacity and growth performance, mineral digestibility, tibia and intestinal characteristics in broiler chickens. Verlag Eugen Ulmer, 2018. http://dx.doi.org/10.1399/eps.2018.250.
Sohn, Woon-Mok y Jong-Yil Chai. Anisakiosis (Anisakidosis). Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0070.
Capítulos de libros sobre el tema "Modèle intestinal in vitro":
Sambruy, Yula, S. Ferruzza, G. Ranaldi y I. De Angelis. "Intestinal Cell Culture Models". En Cell Culture Methods for In Vitro Toxicology, 97–113. Dordrecht: Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-017-0996-5_7.
Vieira, Adriana, Ana Gramacho, Dora Rolo, Nádia Vital, Maria João Silva y Henriqueta Louro. "Cellular and Molecular Mechanisms of Toxicity of Ingested Titanium Dioxide Nanomaterials". En Advances in Experimental Medicine and Biology, 225–57. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-88071-2_10.
Almeida, Hugo, Amélia C. F. Vieira, João Teixeira, Maria João Gomes, Pedro Barrocas, Teófilo Vasconcelos y Bruno Sarmento. "Cell-Based Intestinal In Vitro Models for Drug Absorption Screening". En Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays, 1–22. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-73317-9_94-1.
Morita, Atsuya, Mizuho Nakayama, Hiroko Oshima y Masanobu Oshima. "In Vitro and In Vivo Models for Metastatic Intestinal Tumors Using Genotype-Defined Organoids". En Methods in Molecular Biology, 19–30. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3331-1_2.
Wang, Tingting, Xianglong Li y Qinghua Liao. "Stool and Intestinal Microbiota Examination". En In Vitro Diagnostic Industry in China, 341–59. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-3110-1_20.
Lallés, J. P. y I. P. Oswald. "Chapter 8: Techniques for investigating gut function in vivo, ex vivo and in vitro in monogastric farm animals". En Intestinal health, 191–218. The Netherlands: Wageningen Academic Publishers, 2015. http://dx.doi.org/10.3920/978-90-8686-792-9_8.
Jardé, Thierry, Genevieve Kerr, Reyhan Akhtar y Helen E. Abud. "Modelling Intestinal Carcinogenesis Using In Vitro Organoid Cultures". En Methods in Molecular Biology, 41–52. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7568-6_4.
Chan, Wing Hei, Diana Micati, Rebekah M. Engel, Genevieve Kerr, Reyhan Akhtar, Thierry Jardé y Helen E. Abud. "Modeling Intestinal Carcinogenesis Using In Vitro Organoid Cultures". En Methods in Molecular Biology, 55–69. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3331-1_5.
Chen, Yun, Chuan Li, Ya-Hui Tsai y Sheng-Hong Tseng. "Intestinal Crypt Organoid: Isolation of Intestinal Stem Cells, In Vitro Culture, and Optical Observation". En Methods in Molecular Biology, 215–28. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/7651_2017_21.
Smith, Philip L. "Methods for Evaluating Intestinal Permeability and Metabolism in Vitro". En Pharmaceutical Biotechnology, 13–34. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-1863-5_2.
Actas de conferencias sobre el tema "Modèle intestinal in vitro":
Stan, Miruna y Alina Strugari. "Nanoparticle Intestinal Transport Characterization Using In Vitro Co-Culture Models". En 1st International Online Conference on Nanomaterials. Basel, Switzerland: MDPI, 2018. http://dx.doi.org/10.3390/iocn_2018-1-05480.
Elisa Ramos Magalhães, Ana, Juliana Alves Macedo y Mônica Cristina Lopes do Carmo. "AVALIAÇÃO DO EXTRATO DE FOLHAS DE PASSIFLORA EDULIS EM MODELO IN VITRO DE INFLAMAÇÃO INTESTINAL". En XXV Congresso de Iniciação Cientifica da Unicamp. Campinas - SP, Brazil: Galoa, 2017. http://dx.doi.org/10.19146/pibic-2017-77869.
Lukyanov, Alexandr D., Danila Yu Donskoy, Miroslav A. Vernezi, Maria S. Mazanko y Svetlana G. Studennikova. "EXPERIENCE IN DEVELOPING MODELS OF ARTIFICIAL GASTROINTESTINAL TRACTS OF ANIMALS". En XXVII savetovanje o biotehnologiji. University of Kragujevac, Faculty of Agronomy, 2022. http://dx.doi.org/10.46793/sbt27.193l.
Williams, Courtney M., Jessica L. Harper, Hui Huang, Pat Boland, Qing Zhang, George D. Yancopoulos, Zhe Li y O. Gavin Thurston. "Abstract 2644: In vivo and in vitro stem cell models suggest a role for LGR5 in regulating intestinal epithelial lineage specification." En Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2644.
Hoppensteadt, D., A. Kumar, J. Fareed y J. Mardigian. "STUDIES ON THE ANTICOAGULANT AND ANTITHROMBOTIC ACTIONS OF DERMATANS AND THEIR SULFATED DERIVATIVES". En XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643241.
Boyd, Abigail, Joey Talbert y Nuria Acevedo. "Addition of cholesterol esterase substantially enhances phytosterol ester bioaccessibility in emulsions with different droplet sizes using a standardized in vitro digestion model". En 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/oplq4898.
Akpinar, Ayse Nur, Selvi Secil Sahin, Büşra Moran Bozer, Aziz Tekin y Cansu Ekin Gumus-Bonacına. "Effect of Food Emulsions on the Cytotoxicity of 3-chloropropane-1,2-diol Esters". En 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/emiq3563.
Hippenstiel, S., B. Brell, C. Zu Dohna, M. Dorenberg, AC Hocke, H. Martens, N. Suttorp y B. Temmesfeld-Wollbruck. "Adrenomedullin Reduces Sepsis-Related Intestinal Epithelial PermeabilityIn VivoandIn Vitro." En American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1162.
Alno, N., F. Clipet, P. Pellen-Mussi, G. Cathelineau y G. De Mello. "Mise au point d’un modèle de culture tridimensionnelle pour l’évaluation de substituts osseux in vitro". En 56ème Congrès de la SFMBCB. Les Ulis, France: EDP Sciences, 2011. http://dx.doi.org/10.1051/sfmbcb/20115602007.
Pferschy-Wenzig, EM, A. Roßmann, K. Koskinen, K. Ardjomand-Woelkart, G. Meng, E. Koch, C. Moissl-Eichinger y R. Bauer. "Interactions between hawthorn extract WS® 1442 and human intestinal microbiota in vitro". En GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608400.
Informes sobre el tema "Modèle intestinal in vitro":
Shpigel, Nahum, Raul Barletta, Ilan Rosenshine y Marcelo Chaffer. Identification and characterization of Mycobacterium paratuberculosis virulence genes expressed in vivo by negative selection. United States Department of Agriculture, enero de 2004. http://dx.doi.org/10.32747/2004.7696510.bard.
Harpaz, Sheenan, Steven G. Hughes y Pinhas Lindner. Optimization of Diet for Post Larvel/Juvenile Sea Bass and Hybrid Stripped Bass Based on Enzymatic Profiles of their Digestive Tracts. United States Department of Agriculture, diciembre de 1995. http://dx.doi.org/10.32747/1995.7604924.bard.