Literatura académica sobre el tema "MiRNA-screening"
Crea una cita precisa en los estilos APA, MLA, Chicago, Harvard y otros
Consulte las listas temáticas de artículos, libros, tesis, actas de conferencias y otras fuentes académicas sobre el tema "MiRNA-screening".
Junto a cada fuente en la lista de referencias hay un botón "Agregar a la bibliografía". Pulsa este botón, y generaremos automáticamente la referencia bibliográfica para la obra elegida en el estilo de cita que necesites: APA, MLA, Harvard, Vancouver, Chicago, etc.
También puede descargar el texto completo de la publicación académica en formato pdf y leer en línea su resumen siempre que esté disponible en los metadatos.
Artículos de revistas sobre el tema "MiRNA-screening"
Ying, Huanchun, Jing Lyu, Tianshu Ying, Jun Li, Shanshan Jin, Jingru Shao, Lili Wang y Hongying Xu. "Risk miRNA screening of ovarian cancer based on miRNA functional synergistic network". Journal of Ovarian Research 7, n.º 1 (2014): 9. http://dx.doi.org/10.1186/1757-2215-7-9.
Texto completoNielsen, Søren Jensby, Hanni Willenbrock, Jacob Fog, Jan Stenvang, Thorarinn Blondal, Torben Orntoft, Nils Brünner, Claus Lindbjerg Andersen, Hans J. Nielsen y Adam Baker. "Validation of a plasma-based miRNA PCR test for early detection of colorectal cancer." Journal of Clinical Oncology 30, n.º 4_suppl (1 de febrero de 2012): 424. http://dx.doi.org/10.1200/jco.2012.30.4_suppl.424.
Texto completoEulalio, Ana y Miguel Mano. "MicroRNA Screening and the Quest for Biologically Relevant Targets". Journal of Biomolecular Screening 20, n.º 8 (30 de marzo de 2015): 1003–17. http://dx.doi.org/10.1177/1087057115578837.
Texto completoRoa, W., L. J. Xing, J. Amanie, A. Fairchild, Z. Gabos, T. Nijjar, R. Scrimger y D. Yee. "14 SCREENING LUNG CANCER WITH MIRNA EXPRESSION PROFILES". Radiotherapy and Oncology 92 (septiembre de 2009): S5. http://dx.doi.org/10.1016/s0167-8140(12)72401-5.
Texto completoOka, Hiroyuki, Koichi Masuno, Takeki Uehara, Toru Okamoto, Yoshiharu Matsuura, Toru Nakano y Shinpei Yamaguchi. "Novel miRNA biomarkers for genotoxicity screening in mouse". Toxicology 404-405 (julio de 2018): 68–75. http://dx.doi.org/10.1016/j.tox.2018.05.009.
Texto completoSiebert, Marina, Wendy Westbroek, Yu-Chi Chen, Nima Moaven, Yan Li, Maria Luiza Saraiva-Pereira, Scott Martin y Ellen Sidransky. "MiRNAs and glucocerebrosidase: lessons from miRNA mimic screening". Molecular Genetics and Metabolism 111, n.º 2 (febrero de 2014): S98. http://dx.doi.org/10.1016/j.ymgme.2013.12.239.
Texto completoZanutto, Susanna, Chiara Maura Ciniselli, Antonino Belfiore, Mara Lecchi, Enzo Masci, Gabriele Delconte, Massimo Primignani et al. "Plasma miRNA‐based signatures in CRC screening programs". International Journal of Cancer 146, n.º 4 (5 de agosto de 2019): 1164–73. http://dx.doi.org/10.1002/ijc.32573.
Texto completoLorenz, Daniel A., Steve Vander Roest, Martha J. Larsen y Amanda L. Garner. "Development and Implementation of an HTS-Compatible Assay for the Discovery of Selective Small-Molecule Ligands for Pre-microRNAs". SLAS DISCOVERY: Advancing the Science of Drug Discovery 23, n.º 1 (7 de julio de 2017): 47–54. http://dx.doi.org/10.1177/2472555217717944.
Texto completoMellis, David y Andrea Caporali. "MicroRNA-based therapeutics in cardiovascular disease: screening and delivery to the target". Biochemical Society Transactions 46, n.º 1 (1 de diciembre de 2017): 11–21. http://dx.doi.org/10.1042/bst20170037.
Texto completoPfaff, Nils, Jan Fiedler, Angelika Holzmann, Axel Schambach, Thomas Moritz, Tobias Cantz y Thomas Thum. "miRNA screening reveals a new miRNA family stimulating iPS cell generation via regulation of Meox2". EMBO reports 12, n.º 11 (23 de septiembre de 2011): 1153–59. http://dx.doi.org/10.1038/embor.2011.176.
Texto completoTesis sobre el tema "MiRNA-screening"
Bhajun, Ricky. "Une approche réseau pour l’inférence du rôle des microARN dans la corégulation des processus biologiques". Thesis, Université Grenoble Alpes (ComUE), 2015. http://www.theses.fr/2015GREAS045/document.
Texto completoRNA interference is a process in which a small non-coding RNA will bind to a specific messenger RNA and regulate its expression. This evolutionary conserved mechanism is found in all superior eukaryotes from plants to mammals. Nowadays, we know that RNA interference is a major regulatory process involved in developmental biology and tumor progression. MicroRNAs (miRNAs) are endogenous (coded in and produced by the cell) non-coding RNAs which are able to regulate a whole set of genes, typically hundreds of genes. This doctoral thesis consisted in the analysis of the miRNA mediated coregulation through a network approach based on target sharing. Coregulation is the process where many different miRNAs will regulate the same set of genes and thus the same biological process. In particular, the work consisted in the inference of a miRNA network, in its topological analysis and also its biological interpretation. Indeed, the final aim of the work was to generate new biological hypothesis. As such, two different groups of miRNAs were first retrieved. One of them was predicted to be involved in the small GTPase signaling and was further validated in vitro. Moreover, a miRNA community involved in the maintenance of stem cells pluripotency was also discovered. Finally, a systemic analysis of the target-based miRNAs network was conducted to better understand their integration with biologic networks and their role in cell fate
Naidoo, Jerolen. "Functional miRNA-based Phenotypic Screening as a tool to delineate HIV-host interactions and facilitate Novel Drug Discovery". Thesis, Faculty of Health Sciences, 2021. http://hdl.handle.net/11427/33227.
Texto completoVillegas, Mirón Pablo 1991. "A Comprehensive screening of X-linked and miRNA-driven signatures of positive selection and the role of cis-regulatory elements in the human genome". Doctoral thesis, TDX (Tesis Doctorals en Xarxa), 2021. http://hdl.handle.net/10803/672657.
Texto completoLa historia evolutiva del genoma humano ha sido configurada por la selección de numerosos elementos en respuesta a distintas presiones evolutivas. El análisis de adaptaciones regulatorias y de las particularidades de los cromosomas sexuales son clave para entender las distintas consecuencias de algunos de estos procesos. En esta tesis describimos cómo procesos de selección reciente han configurado el cromosoma X en distintas poblaciones humanas, centrándonos en varios candidatos bajo selección, sus propiedades hereditarias y el papel de elementos regulatorios. También describimos la relevancia de enhancers humanos en los programas regulatorios de tejidos específicos. La expresión de genes implicados en las funciones específicas de tejido aparece principalmente regulada por enhancers ubicados en intrones, por otro lado, genes implicados en el mantenimiento básico de la célula están predominantemente controlados por enhancers intergénicos. También analizamos el papel evolutivo de microRNAs humanos, con especial énfasis en patrones de diversidad globales y su implicación en prevalencias poblaciones de algunas de las enfermedades humanas más comunes.
Mirihana, Arachchilage Gayan S. "REGULATORY ROLES OF G-QUADRUPLEX IN microRNA PROCESSING AND mRNA TRANSLATION". Kent State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=kent1469576783.
Texto completoDojahn, Claudine. "Synthese und Screening von Inhibitoren der mikroRNA-Reifung". Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2013. http://dx.doi.org/10.18452/16748.
Texto completoThe objective of this work was the synthesis of small molecules, which bind to pre-miRNAs to prevent their maturation to fully active miRNAs. To create a substance library of bivalent inhibitors, the RNA binding motifs 2-deoxystreptamine as well as neamine were alkyne modified and linked with several bisazides via a copper catalyzed alkyne-azide cycloaddition (CuAAC). Hence, optimized syntheses of the basic building blocks along with an effective and reliable CuAAC-protocol were established. 88 test substances were isolated in good yield and high purity. Finally they were analyzed with regard to their potential to selectively inhibit the miRNA maturation. For this purpose, the assay was performed under competitive conditions with a set of two pre-miRNA-pairs. The initial screening revealed several inhibitors with IC50-values in the lower µM range. The second focus of this work was on the development of a synthetic access to alkyne modified ribonucleotides to establish a chemo-enzymatic functionalization strategy for RNAs using in-vitro-transcription, ligation and CuAAC. In this context, the syntheses of 3‘,5‘-O,O-bisphosphate-5-ethinyl uridine and O-(5‘-guanosine)-O-propargyl monophos-phate are described for the first time. The guanosine monophosphate was used as transcription starter to address the 5’-end of RNA and was consecutively labeled with an azido-tagged quencher. The uridine bisphosphate was conjugated with a fluorophor and introduced to the 3’-end of RNAs by T4 RNA ligase 1. Moreover, the uridine bisphosphate can be ligated to the 3’-end without a fluorophor attached, to serve as a connecting point for a further ligation with an oligonucleotide of any length. Thereby, the former terminal alkynylated uridine was shifted to a defined internal position by successive enzymatic reactions and was successfully derivatized with a fluorophor by CuAAC.
Capítulos de libros sobre el tema "MiRNA-screening"
Han, Bo. "Screening miRNA for Functional Significance by 3D Cell Culture System". En MicroRNA Protocols, 193–201. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7601-0_16.
Texto completoArmstrong, Richard N., Hilary A. A. Colyer y Ken I. Mills. "Screening for miRNA Expression Changes Using Quantitative PCR (Q-PCR)". En Methods in Molecular Biology, 293–302. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-612-8_18.
Texto completoArmstrong, Richard N., Hilary A. A. Colyer y Ken I. Mills. "Screening for miRNA Expression Changes Using Quantitative PCR (Q-PCR)". En Methods in Molecular Biology, E1. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-612-8_29.
Texto completoGuijarro, Maria V. y Amancio Carnero. "Genome-Wide miRNA Screening for Genes Bypassing Oncogene-Induced Senescence". En Methods in Molecular Biology, 53–68. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-6670-7_5.
Texto completoLi, Yan, Bing Chen y Shenglin Huang. "Identification of circRNAs for miRNA Targets by Argonaute2 RNA Immunoprecipitation and Luciferase Screening Assays". En Methods in Molecular Biology, 209–18. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7562-4_17.
Texto completoHaga, Christopher L., Sai Pradeep Velagapudi, Jessica L. Childs-Disney, Jacqueline Strivelli, Matthew D. Disney y Donald G. Phinney. "Rapid Generation of miRNA Inhibitor Leads by Bioinformatics and Efficient High-Throughput Screening Methods". En Methods in Molecular Biology, 179–98. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-6563-2_13.
Texto completoPeriwal, Vinita y Vinod Scaria. "Machine Learning Approaches Toward Building Predictive Models for Small Molecule Modulators of miRNA and Its Utility in Virtual Screening of Molecular Databases". En Methods in Molecular Biology, 155–68. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-6563-2_11.
Texto completo"In Silico Screening of miRNA Target Sites". En Encyclopedia of Systems Biology, 1015. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_100674.
Texto completoPower, Michael L., Caroline W. Quaglieri, Eda G. Reed y Jay Schulkin. "The Functions of MicroRNA in Female Reproduction". En Integrating Evolutionary Biology into Medical Education, 132–47. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198814153.003.0008.
Texto completoJayasinghe, Ravindri, Umesh Jayarajah y Sanjeewa Seneviratne. "Circulating Biomarkers in Predicting Pathological Response to Neoadjuvant Therapy for Colorectal Cancer". En Biomarkers in Medicine, 113–32. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815040463122010008.
Texto completoActas de conferencias sobre el tema "MiRNA-screening"
Koga, Yoshikatsu, Nobuyoshi Yamazaki, Yasuo Kakugawa, Takahisa Matsuda, Masaaki Ito, Yutaka Saito, Hiroshi Saito y Yasuhiro Matsumura. "Abstract 5292: Multitarget fecal miRNA test combined with fecal occult blood test and fecal miRNA test for colorectal cancer screening". En Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-5292.
Texto completoKoga, Yoshikatsu, Masahiro Yasunaga y Yasuhiro Matsumura. "Abstract 4448: Fecal miRNA test using microRNA expressions of exfoliated colonocytes for colorectalcancer screening". En Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-4448.
Texto completoHeneghan, HM, N. Miller, N. Healy, J. Newell y MJ Kerin. "Abstract P3-10-02: Circulating miRNA Signature: Potential Screening and Prognostic Tool for Breast Cancer". En Abstracts: Thirty-Third Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 8‐12, 2010; San Antonio, TX. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/0008-5472.sabcs10-p3-10-02.
Texto completoMichailidi, Christina, Tal Hadar, Kaitlyn Zenner, Mark Schoenberg, George Netto, David Sidransky y Mohammad O. Hoque. "Abstract 4193: Exposure to arsenic and miRNA deregulation: a potential non-invasive screening tool for urothelial cell carcinoma." En Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-4193.
Texto completoNaccarati, Alessio, Daniela De Maria, Francesca Cordero, Barbara Pardini, Stavrula Gouzounis, Maddalena Arigoni, Raffaella Rizzolo et al. "Abstract LB-366: miRNA as markers of CIN risk and persistence for optimization of HPV-based cervical cancer screening". En Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-lb-366.
Texto completoDeng, Jianzhi, Yuehan Zhou, Xiaohui Cheng y Mingjun Xu. "Screening and Analysis of lncRNA Biomarkers and the Relationship with the Corresponding Regulatory miRNA for Progressive Acute Lymphoblastic Leukemia". En Proceedings of the 2019 International Conference on Modeling, Simulation and Big Data Analysis (MSBDA 2019). Paris, France: Atlantis Press, 2019. http://dx.doi.org/10.2991/msbda-19.2019.51.
Texto completoBoeri, Mattia, Carla Verri, Cristina Borzi, Todd Holscher, Matteo Dugo, Andrea Devecchi, Elisa Romeo et al. "Abstract 2753: Mutational profiles from targeted NGS combine with miRNA-based liquid biopsy to predict survival in LDCT screening-detected lung cancers". En Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-2753.
Texto completoDriscoll, James J. y Sajjeev Jagannathan. "Abstract 1462: Tandem genome-wide and functional screening reveals that MiRNA-29 regulates the proteasome activator PSME4 to promote therapeutic resistance in myeloma". En Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-1462.
Texto completoÖstling, Päivi, Suvi-Katri Leivonen, Pekka Kohonen, Anna Aakula, Petteri Hintsanen, Tero Aittokallio, Merja Perälä y Olli Kallioniemi. "Abstract 5273: Systematic functional screening, miRNA and target expression analyses reveal miR-19, -124, -583, -129 and -876 as key nodes in prostate cancer proliferation networks." En Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-5273.
Texto completoInformes sobre el tema "MiRNA-screening"
Whitham, Steven A., Amit Gal-On y Victor Gaba. Post-transcriptional Regulation of Host Genes Involved with Symptom Expression in Potyviral Infections. United States Department of Agriculture, junio de 2012. http://dx.doi.org/10.32747/2012.7593391.bard.
Texto completo