Artículos de revistas sobre el tema "Microhomology mediated recombination"
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Jiang, Yuning. "Contribution of Microhomology to Genome Instability: Connection between DNA Repair and Replication Stress". International Journal of Molecular Sciences 23, n.º 21 (26 de octubre de 2022): 12937. http://dx.doi.org/10.3390/ijms232112937.
Texto completoXu, Yijiang, Hang Zhou, Ginell Post, Hong Zan y Paolo Casali. "Rad52 mediates class-switch DNA recombination to IgD". Journal of Immunology 208, n.º 1_Supplement (1 de mayo de 2022): 112.17. http://dx.doi.org/10.4049/jimmunol.208.supp.112.17.
Texto completoLee-Theilen, Mieun, Allysia J. Matthews, Dierdre Kelly, Simin Zheng y Jayanta Chaudhuri. "CtIP promotes microhomology-mediated alternative end joining during class-switch recombination". Nature Structural & Molecular Biology 18, n.º 1 (5 de diciembre de 2010): 75–79. http://dx.doi.org/10.1038/nsmb.1942.
Texto completoFrancis, Nigel J., Bairbre McNicholas, Atif Awan, Mary Waldron, Donal Reddan, Denise Sadlier, David Kavanagh et al. "A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome". Blood 119, n.º 2 (12 de enero de 2012): 591–601. http://dx.doi.org/10.1182/blood-2011-03-339903.
Texto completoAhrabi, Sara, Sovan Sarkar, Sophia X. Pfister, Giacomo Pirovano, Geoff S. Higgins, Andrew C. G. Porter y Timothy C. Humphrey. "A role for human homologous recombination factors in suppressing microhomology-mediated end joining". Nucleic Acids Research 44, n.º 12 (29 de abril de 2016): 5743–57. http://dx.doi.org/10.1093/nar/gkw326.
Texto completoChan, C. Y., M. Kiechle, P. Manivasakam y R. H. Schiestl. "Ionizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae". Nucleic Acids Research 35, n.º 15 (11 de julio de 2007): 5051–59. http://dx.doi.org/10.1093/nar/gkm442.
Texto completoLing, Alexanda K., Clare C. So, Michael X. Le, Audrey Y. Chen, Lisa Hung y Alberto Martin. "Double-stranded DNA break polarity skews repair pathway choice during intrachromosomal and interchromosomal recombination". Proceedings of the National Academy of Sciences 115, n.º 11 (22 de febrero de 2018): 2800–2805. http://dx.doi.org/10.1073/pnas.1720962115.
Texto completoChan, Cecilia Y. y Robert H. Schiestl. "Rad1, rad10 and rad52 Mutations Reduce the Increase of Microhomology Length during Radiation-Induced Microhomology-Mediated Illegitimate Recombination in Saccharomyces cerevisiae". Radiation Research 172, n.º 2 (1 de agosto de 2009): 141. http://dx.doi.org/10.1667/rr1675.1.
Texto completoNagai, Koki, Hirohito Shima, Miki Kamimura, Junko Kanno, Erina Suzuki, Akira Ishiguro, Satoshi Narumi, Shigeo Kure, Ikuma Fujiwara y Maki Fukami. "Xp22.31 Microdeletion due to Microhomology-Mediated Break-Induced Replication in a Boy with Contiguous Gene Deletion Syndrome". Cytogenetic and Genome Research 151, n.º 1 (2017): 1–4. http://dx.doi.org/10.1159/000458469.
Texto completoMeyer, Damon, Becky Xu Hua Fu y Wolf-Dietrich Heyer. "DNA polymerases δ and λ cooperate in repairing double-strand breaks by microhomology-mediated end-joining in Saccharomyces cerevisiae". Proceedings of the National Academy of Sciences 112, n.º 50 (25 de noviembre de 2015): E6907—E6916. http://dx.doi.org/10.1073/pnas.1507833112.
Texto completoXu, Ran, Ziyi Pan y Takuro Nakagawa. "Gross Chromosomal Rearrangement at Centromeres". Biomolecules 14, n.º 1 (24 de diciembre de 2023): 28. http://dx.doi.org/10.3390/biom14010028.
Texto completoRobert, Isabelle, Françoise Dantzer y Bernardo Reina-San-Martin. "Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination". Journal of Experimental Medicine 206, n.º 5 (13 de abril de 2009): 1047–56. http://dx.doi.org/10.1084/jem.20082468.
Texto completoWang, Xiaobin S., Junfei Zhao, Foon Wu-Baer, Zhengping Shao, Brian J. Lee, Olivia M. Cupo, Raul Rabadan, Jean Gautier, Richard Baer y Shan Zha. "CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining". Proceedings of the National Academy of Sciences 117, n.º 41 (28 de septiembre de 2020): 25700–25711. http://dx.doi.org/10.1073/pnas.2010972117.
Texto completoChen, Changming, Xiaoling Xie, Xi Wu, Yeling Lu, Xuefeng Wang, Wenman Wu, Yiqun Hu y Qiulan Ding. "Complex recombination with deletion in the F8 and duplication in the TMLHE mediated by int22h copies during early embryogenesis". Thrombosis and Haemostasis 117, n.º 08 (2017): 1478–85. http://dx.doi.org/10.1160/th17-01-0046.
Texto completoSaribasak, Huseyin, Robert W. Maul, Zheng Cao, Rhonda L. McClure, William Yang, Daniel R. McNeill, David M. Wilson y Patricia J. Gearhart. "XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in Igh genes". Journal of Experimental Medicine 208, n.º 11 (3 de octubre de 2011): 2209–16. http://dx.doi.org/10.1084/jem.20111135.
Texto completoEhrenstein, M. R., C. Rada, A. M. Jones, C. Milstein y M. S. Neuberger. "Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination". Proceedings of the National Academy of Sciences 98, n.º 25 (20 de noviembre de 2001): 14553–58. http://dx.doi.org/10.1073/pnas.241525998.
Texto completoChen, Xiaojiang S. y Richard T. Pomerantz. "DNA Polymerase θ: A Cancer Drug Target with Reverse Transcriptase Activity". Genes 12, n.º 8 (27 de julio de 2021): 1146. http://dx.doi.org/10.3390/genes12081146.
Texto completoBothmer, Anne, Davide F. Robbiani, Niklas Feldhahn, Anna Gazumyan, Andre Nussenzweig y Michel C. Nussenzweig. "53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination". Journal of Experimental Medicine 207, n.º 4 (5 de abril de 2010): 855–65. http://dx.doi.org/10.1084/jem.20100244.
Texto completoDecottignies, Anabelle. "Microhomology-Mediated End Joining in Fission Yeast Is Repressed by Pku70 and Relies on Genes Involved in Homologous Recombination". Genetics 176, n.º 3 (4 de mayo de 2007): 1403–15. http://dx.doi.org/10.1534/genetics.107.071621.
Texto completoDing, Qiulan, Guoling You, Jing Dai, Xiaodong Xi, Hongli Wang, Xi Wu, Yeling Lu y Xuefeng Wang. "Characterisation of large F9 deletions in seven unrelated patients with severe haemophilia B". Thrombosis and Haemostasis 112, n.º 09 (2014): 459–65. http://dx.doi.org/10.1160/th13-12-1060.
Texto completoYou, Guoling, Kun Chi, Yeling Lu, Qiulan Ding, Jing Dai, Xiaodong Xi, Hongli Wang y Xuefeng Wang. "Identification and characterisation of a novel aberrant pattern of intron 1 inversion with concomitant large insertion and deletion within the F8 gene". Thrombosis and Haemostasis 112, n.º 08 (2014): 264–70. http://dx.doi.org/10.1160/th13-10-0892.
Texto completoKohli, Ajay, Simon Griffiths, Natalia Palacios, Richard M Twyman, Philippe Vain, David A. Laurie y Paul Christou. "Molecular characterization of transforming plasmid rearrangements in transgenic rice reveals a recombination hotspot in the CaMV 35S promoter and confirms the predominance of microhomology mediated recombination". Plant Journal 17, n.º 6 (marzo de 1999): 591–601. http://dx.doi.org/10.1046/j.1365-313x.1999.00399.x.
Texto completoFiori, Mariangela Stefania, Luca Ferretti, Antonello Di Nardo, Lele Zhao, Susanna Zinellu, Pier Paolo Angioi, Matteo Floris et al. "A Naturally Occurring Microhomology-Mediated Deletion of Three Genes in African Swine Fever Virus Isolated from Two Sardinian Wild Boars". Viruses 14, n.º 11 (14 de noviembre de 2022): 2524. http://dx.doi.org/10.3390/v14112524.
Texto completoFeng, Wanjuan, Dennis A. Simpson, Jang-Eun Cho, Juan Carvajal-Garcia, Chelsea M. Smith, Kathryn M. Headley, Nate Hathaway, Dale A. Ramsden y Gaorav P. Gupta. "Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks". Nucleic Acids Research 49, n.º 9 (8 de mayo de 2021): 5095–105. http://dx.doi.org/10.1093/nar/gkab299.
Texto completoStachler, Aris-Edda, Julia Wörtz, Omer S. Alkhnbashi, Israela Turgeman-Grott, Rachel Smith, Thorsten Allers, Rolf Backofen, Uri Gophna y Anita Marchfelder. "Adaptation induced by self-targeting in a type I-B CRISPR-Cas system". Journal of Biological Chemistry 295, n.º 39 (28 de julio de 2020): 13502–15. http://dx.doi.org/10.1074/jbc.ra120.014030.
Texto completoDahal, Sumedha y Sathees C. Raghavan. "Mitochondrial genome stability in human: understanding the role of DNA repair pathways". Biochemical Journal 478, n.º 6 (19 de marzo de 2021): 1179–97. http://dx.doi.org/10.1042/bcj20200920.
Texto completoWang, Wenjie, Kuan Li, Zhuo Yang, Quancan Hou, Wei W. Zhao y Qianwen Sun. "RNase H1C collaborates with ssDNA binding proteins WHY1/3 and recombinase RecA1 to fulfill the DNA damage repair in Arabidopsis chloroplasts". Nucleic Acids Research 49, n.º 12 (16 de junio de 2021): 6771–87. http://dx.doi.org/10.1093/nar/gkab479.
Texto completoÖz, Robin, Sean M. Howard, Rajhans Sharma, Hanna Törnkvist, Ilaria Ceppi, Sriram KK, Erik Kristiansson, Petr Cejka y Fredrik Westerlund. "Phosphorylated CtIP bridges DNA to promote annealing of broken ends". Proceedings of the National Academy of Sciences 117, n.º 35 (19 de agosto de 2020): 21403–12. http://dx.doi.org/10.1073/pnas.2008645117.
Texto completoZhao, Yuqin, Kaiping Hou, Yu Liu, Yinan Na, Chao Li, Haoyuan Luo y Hailong Wang. "Helicase HELQ: Molecular Characters Fit for DSB Repair Function". International Journal of Molecular Sciences 25, n.º 16 (8 de agosto de 2024): 8634. http://dx.doi.org/10.3390/ijms25168634.
Texto completoDohrn, Lisa, Daniela Salles, Simone Y. Siehler, Julia Kaufmann y Lisa Wiesmüller. "BRCA1-mediated repression of mutagenic end-joining of DNA double-strand breaks requires complex formation with BACH1". Biochemical Journal 441, n.º 3 (16 de enero de 2012): 919–28. http://dx.doi.org/10.1042/bj20110314.
Texto completoTruong, L. N., Y. Li, L. Z. Shi, P. Y. H. Hwang, J. He, H. Wang, N. Razavian, M. W. Berns y X. Wu. "Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells". Proceedings of the National Academy of Sciences 110, n.º 19 (22 de abril de 2013): 7720–25. http://dx.doi.org/10.1073/pnas.1213431110.
Texto completoElert-Dobkowska, Ewelina, Iwona Stepniak, Wiktoria Radziwonik-Fraczyk, Amir Jahic, Christian Beetz y Anna Sulek. "SPAST Intragenic CNVs Lead to Hereditary Spastic Paraplegia via a Haploinsufficiency Mechanism". International Journal of Molecular Sciences 25, n.º 9 (3 de mayo de 2024): 5008. http://dx.doi.org/10.3390/ijms25095008.
Texto completoTomasini, Paula Pellenz, Temenouga Nikolova Guecheva, Natalia Motta Leguisamo, Sarah Péricart, Anne-Cécile Brunac, Jean Sébastien Hoffmann y Jenifer Saffi. "Analyzing the Opportunities to Target DNA Double-Strand Breaks Repair and Replicative Stress Responses to Improve Therapeutic Index of Colorectal Cancer". Cancers 13, n.º 13 (23 de junio de 2021): 3130. http://dx.doi.org/10.3390/cancers13133130.
Texto completoLi, Zhichao y Ralph Bock. "Rapid functional activation of a horizontally transferred eukaryotic gene in a bacterial genome in the absence of selection". Nucleic Acids Research 47, n.º 12 (20 de mayo de 2019): 6351–59. http://dx.doi.org/10.1093/nar/gkz370.
Texto completoLukashchuk, Natalia, Joshua Armenia, Luis Tobalina, Thomas Hedley Carr, Tsveta Milenkova, Ying L. Liu, Richard T. Penson, Mark E. Robson y Elizabeth Harrington. "BRCA reversion mutations mediated by microhomology-mediated end joining (MMEJ) as a mechanism of resistance to PARP inhibitors in ovarian and breast cancer." Journal of Clinical Oncology 40, n.º 16_suppl (1 de junio de 2022): 5559. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.5559.
Texto completoLukashchuk, Natalia, Joshua Armenia, Luis Tobalina, Thomas Hedley Carr, Tsveta Milenkova, Ying L. Liu, Richard T. Penson, Mark E. Robson y Elizabeth Harrington. "BRCA reversion mutations mediated by microhomology-mediated end joining (MMEJ) as a mechanism of resistance to PARP inhibitors in ovarian and breast cancer." Journal of Clinical Oncology 40, n.º 16_suppl (1 de junio de 2022): 5559. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.5559.
Texto completoHays, Michelle, Katja Schwartz, Danica T. Schmidtke, Dimitra Aggeli y Gavin Sherlock. "Paths to adaptation under fluctuating nitrogen starvation: The spectrum of adaptive mutations in Saccharomyces cerevisiae is shaped by retrotransposons and microhomology-mediated recombination". PLOS Genetics 19, n.º 5 (16 de mayo de 2023): e1010747. http://dx.doi.org/10.1371/journal.pgen.1010747.
Texto completoProvasek, Vincent E., Joy Mitra, Vikas H. Malojirao y Muralidhar L. Hegde. "DNA Double-Strand Breaks as Pathogenic Lesions in Neurological Disorders". International Journal of Molecular Sciences 23, n.º 9 (22 de abril de 2022): 4653. http://dx.doi.org/10.3390/ijms23094653.
Texto completoZhao, Zhihua, Hanshuo Zhang, Tuanlin Xiong, Junyi Wang, Di Yang, Dan Zhu, Juan Li et al. "Suppression of SHROOM1 Improves In Vitro and In Vivo Gene Integration by Promoting Homology-Directed Repair". International Journal of Molecular Sciences 21, n.º 16 (13 de agosto de 2020): 5821. http://dx.doi.org/10.3390/ijms21165821.
Texto completoLiu, Yu-Chang, Chih-Hao Huang y Ching-Chun Chang. "A Transcriptomic Analysis of Tobacco Leaf with the Functional Loss of the Plastid rpoB Operon Caused by TALEN-Mediated Double-Strand Breakage". Plants 11, n.º 21 (26 de octubre de 2022): 2860. http://dx.doi.org/10.3390/plants11212860.
Texto completoAnand, Roopesh, Erika Buechelmaier, Ondrej Belan, Matthew Newton, Aleksandra Vancevska, Artur Kaczmarczyk, Tohru Takaki, David S. Rueda, Simon N. Powell y Simon J. Boulton. "HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51". Nature 601, n.º 7892 (22 de diciembre de 2021): 268–73. http://dx.doi.org/10.1038/s41586-021-04261-0.
Texto completoAlexander, Jessica L., Kelly Beagan, Terry L. Orr-Weaver y Mitch McVey. "Multiple mechanisms contribute to double-strand break repair at rereplication forks inDrosophilafollicle cells". Proceedings of the National Academy of Sciences 113, n.º 48 (14 de noviembre de 2016): 13809–14. http://dx.doi.org/10.1073/pnas.1617110113.
Texto completoTsuji, Hideo, Hiroko Ishii-Ohba, Takanori Katsube, Hideki Ukai, Shiro Aizawa, Masahiro Doi, Kyoji Hioki y Toshiaki Ogiu. "Involvement of Illegitimate V(D)J Recombination or Microhomology-Mediated Nonhomologous End-Joining in the Formation of Intragenic Deletions of the Notch1 Gene in Mouse Thymic Lymphomas". Cancer Research 64, n.º 24 (15 de diciembre de 2004): 8882–90. http://dx.doi.org/10.1158/0008-5472.can-03-1163.
Texto completoHaberland, Vivien M. M., Simon Magin, George Iliakis y Andrea Hartwig. "Impact of Manganese and Chromate on Specific DNA Double-Strand Break Repair Pathways". International Journal of Molecular Sciences 24, n.º 12 (20 de junio de 2023): 10392. http://dx.doi.org/10.3390/ijms241210392.
Texto completoJiang, Yuning y Tarek Abbas. "Abstract 6107: Novel roles for AMBRA1 in regulating DNA double-strand breaks". Cancer Research 83, n.º 7_Supplement (4 de abril de 2023): 6107. http://dx.doi.org/10.1158/1538-7445.am2023-6107.
Texto completoYan, Dan, Yao Zhang, Yan Zhang, Jingxi Zhang, Bin Wang, Huixian Chen, Jingxue Shi, Xiaoling Lin, Jincong Zhuo y Kevin Zhou. "Abstract 4532: Discovery of DAT-1000A, a potent Polθ inhibitor that significantly enhances anti-tumor efficacy in combination with PARP inhibitor in homologous-recombination-deficient tumors". Cancer Research 84, n.º 6_Supplement (22 de marzo de 2024): 4532. http://dx.doi.org/10.1158/1538-7445.am2024-4532.
Texto completoPatterson-Fortin, Jeffrey, Heta Jadhav, Constantia Pantelidou, Tin Phan, Carter Grochala, Anita K. Mehta, Jennifer L. Guerriero et al. "Abstract 6190: Polymerase theta inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in BRCA-deficient cancers". Cancer Research 83, n.º 7_Supplement (4 de abril de 2023): 6190. http://dx.doi.org/10.1158/1538-7445.am2023-6190.
Texto completoLe, Bac Viet, Umeshkumar Vekariya, Monika Toma, Margaret Nieborowska-Skorska, Marie-Christine Caron, George Vassiliou, Malgorzata Gozdecka et al. "Inactivation of DNA Polymerase Theta (PolΘ) Is Synthetic Lethal in DNMT3A Mutated Myeloid Malignancies - Potential Clinical Applications". Blood 142, Supplement 1 (28 de noviembre de 2023): 580. http://dx.doi.org/10.1182/blood-2023-174333.
Texto completoSamnotra, Vivek, Veronica Moroz, Luda Shtessel, Mita Kuchimanchi, Patrick Hanafin, Malar Pannirselvam, Aishwarya Bhaskar et al. "First-in-human, phase 1/2 study of GSK4524101, an oral DNApolymerase theta inhibitor (POLQi), alone or combined with the poly(ADP-ribose) polymerase (PARP) inhibitor (PARPi) niraparib in adults with solid tumors." Journal of Clinical Oncology 42, n.º 16_suppl (1 de junio de 2024): TPS3174. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.tps3174.
Texto completoToma, Monika, Margaret Nieborowska-Skorska, Adam Karami, Monika Pepek, Tomasz Stoklosa y Tomasz Skorski. "Clonal Targeting of DNA Damage Response Pathways Eradicates Myeloproliferative Neoplasms". Blood 142, Supplement 1 (28 de noviembre de 2023): 120. http://dx.doi.org/10.1182/blood-2023-174280.
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