Tesis sobre el tema "Masks – Mali"
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Devineau, Camille. "En présence des génies : musique, danse et joie rituelles dans la performance des Masques Blancs chez les Bwaba du Burkina Faso". Thesis, Paris 10, 2019. http://www.theses.fr/2019PA100162.
Texto completoThe interplay of three expressive modes (music, dance and emotional display) underlie the workings of the White Mask dance ritual among the Bwaba people of Burkina Faso, giving shape to its main concern which is to make manifest a relationship between humans and bush spirits. Although tied to the principal Bwaba cult of the do, it is this ritual’s close association with griots and the connection with bush spirits that it puts into effect counts the most. By providing an intermediary space allowing for interactions between visible and invisible realms, this ritual renders certain aspects of the relationship between griots and bush spirits perceptible. By jointly implementing musical and dance forms, as well as a number of stipulated expressions of delight, White Mask performances allow participants to experience bush spirits’ presence and their benevolent involvement. While music anchors the ritual in the visible realm, the masked dance allows the invisible to intrude into the visible, human one. As for expressions of delight, they bear witness to the benevolent nature of the relationship between humans and bush spirits that this ritual seeks to bring about. Music, dance and emotional expression, then, compose a totality whereby the greater or lesser success of a White Mask performance can be appreciated in terms of concrete feelings
Kempka, Martin. "Improved mass accuracy in MALDI-TOF-MS analysis". Licentiate thesis, Stockholm : Division of Analytical Chemistry, Royal Institute of Technology, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-313.
Texto completoRodrigues, Lívia Riberti 1988. "Análise de impurezas de formas farmacêuticas sólidas por MALDI Mass Spectrometry Imaging (MALDI-MSI)". [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312437.
Texto completoTexto em português e inglês
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas
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Resumo: Atualmente, as doenças cardiovasculares constituem uma das primeiras causas de mortes no Brasil e no mundo. Neste cenário, as estatinas constituem uma notável classe de medicamentos redutores de colesterol e têm sido associadas com uma expressiva diminuição da morbidade e mortalidade cardiovascular para pacientes em prevenção primária ou secundária da doença coronariana. Elas agem inibindo competitivamente a enzima HMG-CoA redutase, através da afinidade destes fármacos pelo sítio ativo da enzima. Esta enzima é responsável por catalisar a conversão do substrato HMG-CoA em mevalonato, um dos precursores do colesterol. A crescente necessidade e busca por medicamentos cada vez mais efetivos traz a preocupação na segurança destes produtos para seus usuários. Neste sentido, o conhecimento das impurezas e produtos de degradação torna-se necessário para garantir sua qualidade. Uma técnica muito utilizada para análises de impurezas e degradantes é a espectrometria de massas, pois é uma técnica sensível e seletiva e permite elucidar as estruturas químicas presentes na formulação do medicamento. Sendo assim, amostras de Atorvastatina cálcica foram analisadas pela técnica de espectrometria de massas por imagem (MALDI-MSI), permitindo a quantificação de impurezas do medicamento através da imagem da distribuição dessa impureza no comprimido. Dessa forma, é possível minimizar o preparo de amostra e obter um melhor conhecimento da formulação
Abstract: Currently, cardiovascular diseases constitute one of the first causes of deaths in Brazil and in the world. In this scenario, the statins are a notable class of medicines and cholesterol reducers have been associated with a significant reduction in cardiovascular morbidity and mortality for patients in primary or secondary prevention of coronary heart disease. They act by inhibiting competitively the enzyme HMG-CoA reductase, through the affinity of these drugs by the active site of the enzyme. This enzyme is responsible for catalyzing the conversion of HMG-CoA to mevalonate substrate, one of the precursors of cholesterol. The growing need and search for increasingly effective drugs brings the concern on the safety of these drugs for their users. In this sense, the knowledge of the impurities and degradation products becomes necessary to ensure their quality. A widely used technique for analysis of impurities and degrading is mass spectrometry, because it is a sensitive and selective technique and allows elucidating the chemical structures of the present formulation of the medicinal product. Thus, samples of Atorvastatin calcium were analyzed by the technique of mass spectrometry imaging (MALDI-MSI), which allows the quantification of impurities from the medicine through the image of the distribution of impurity in the tablet. That way, it is possible minimize sample preparation and get a better understanding of the formulation
Mestrado
Ciencias Biomedicas
Mestra em Ciências Médicas
Grace, Philip Barry. "The detection and determination of saccharides by mass spectrometric methods". Thesis, King's College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287374.
Texto completouk, siricordcc@yahoo co y Cornelia Charito Siricord. "Detection of Phytophthora species by MALDI-TOF mass spectrometry". Murdoch University, 2005. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20070717.125452.
Texto completoWyatt, Mark Francis. "Analysis of acrylic polymers by MALDI-TOF mass spectrometry". Thesis, Durham University, 2001. http://etheses.dur.ac.uk/3962/.
Texto completoSiricord, Cornelia Charito. "Detection of Phytophthora species by MALDI-TOF mass spectrometry". Thesis, Siricord, Cornelia Charito (2005) Detection of Phytophthora species by MALDI-TOF mass spectrometry. PhD thesis, Murdoch University, 2005. https://researchrepository.murdoch.edu.au/id/eprint/314/.
Texto completoSiricord, Cornelia Charito. "Detection of Phytophthora species by MALDI-TOF mass spectrometry". Siricord, Cornelia Charito (2005) Detection of Phytophthora species by MALDI-TOF mass spectrometry. PhD thesis, Murdoch University, 2005. http://researchrepository.murdoch.edu.au/314/.
Texto completoBorsani, M. "BIOINFORMATICS APPROACHES TO MALDI-TOF MASS SPECTROMETRY DATA ANALYSIS". Doctoral thesis, Università degli Studi di Milano, 2013. http://hdl.handle.net/2434/221050.
Texto completoDONG, YONGHUI. "Mass spectrometry imaging: looking fruits at molecular level". Doctoral thesis, country:IT, 2014. http://hdl.handle.net/10449/24270.
Texto completoKirmess, Kristopher Michael. "Investigation of Primary Ion Formation Mechanisms in UV-MALDI-MS Using Excited State Dynamics of Common MALDI Matrices". OpenSIUC, 2015. https://opensiuc.lib.siu.edu/dissertations/1110.
Texto completoMacnamara, Jim R., University of Western Sydney, of Arts Education and Social Sciences College y School of Education and Early Childhood Studies. "Representations of men and male identities in Australian mass media". THESIS_CAESS_EEC_Macnamara_J.xml, 2004. http://handle.uws.edu.au:8081/1959.7/735.
Texto completoDoctor of Philosophy (PhD)
Allwood, Daniel Anthony. "Characterisation and ionisation modelling of matrices in MALDI mass spectrometry". Thesis, University of Hull, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301477.
Texto completoGuan, Bing. "Characterization of Oligosaccharides and Nanoparticles by MALDI-TOF Mass Spectrometry". ScholarWorks@UNO, 2007. http://scholarworks.uno.edu/td/585.
Texto completoGarrison, Megan C. "Size Matters: Television Media Effects on Male Body Image". Xavier University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=xavier1395151552.
Texto completoSegu, Mohideen Mohamed Zaneer. "TARGET MODIFICATION FOR ENHANCED PERFORMANCE MATRIX ASSISTED LASER DESORPTION IONIZATION (MALDI) MASS SPECTROMETRY". Available to subscribers only, 2008. http://proquest.umi.com/pqdweb?did=1674093101&sid=1&Fmt=2&clientId=1509&RQT=309&VName=PQD.
Texto completo"Department of Chemistry." Keywords: Enhanced MALDI, MALDI-MS, On-probe separation, Protein-surface interactions, Sublayers, Surface binding capacity. Includes bibliographical references (p. 130-148). Also available online.
Watson, R. Craig Jr. "Laser-Ionization Time-of-Flight Mass Spectrometry of High Molecular Mass Inorganic Complexes". Thesis, Virginia Tech, 1997. http://hdl.handle.net/10919/35554.
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This thesis describes the characterization of a LI-TOF-MS instrument and confirmation of theoretical time-of-flight mass-separation principles. Several test cases demonstrate the instrument's proper operation and calibration for a wide mass range of analytes. Mass spectral results of three organometallic compounds: i. [Ir(dpp)2Cl2](PF6), ii. {[(bpy)2Ru(dpp)]2IrCl2}(PF6)5, and iii. {[(bpy)2Ru(dpp)]2RuCl2}(PF6)5 under a variety of laser ionization and sample preparation conditions are compared. A complete structural characterization of the monometallic complex, [Ir(dpp)2Cl2](PF6), is presented. The two trimetallic analytes fragmented easily, but significant components of the molecules are successfully identified. After optimizing the ionization and analytical procedure, LI-TOF-MS proved useful in the analysis of high molecular mass metal complexes.
Master of Science
Oduwole, Elizabeth O. "Generation of a database of mass spectra patterns of selected Mycobacterium species using MALDI-ToF mass spectrometry". Thesis, Stellenbosch : Stellenbosch University, 2008. http://hdl.handle.net/10019.1/2838.
Texto completoThe genus Mycobacterium is a group of acid–fast, aerobic, slow- growing organisms which include more than 90 different species. A member of this genus, Mycobacterium tuberculosis, belonging to the Mycobacterium tuberculosis complex (MTB), is the causative agent of tuberculosis (TB). This disease is currently considered a global emergency, with more than 2 million deaths and over 8 million new cases annually. TB is the world’s second most common cause of death after HIV/AIDS. About one-third of the world’s population is estimated to be infected with TB. This catastrophic situation is further compounded by the emergence of Multi Drug Resistant tuberculosis (MDR-TB) and in more recent times, Extensive Drug Resistant tuberculosis (XDR-TB). Early diagnosis is critical to the successful management of patients as it allows informed use of chemotherapy. Also, early diagnosis is also of great importance if the menace of MDR-TB and XDR-TB is to be curbed and controlled. As MTB is highly infectious for humans, it is of paramount importance that TB be diagnosed as early as possible to stop the spread of the disease. Traditional conventional laboratory procedures involving microscopy, culture and sensitivity tests may require turnaround times of 3-4 weeks or longer. Tremendous technological advancement over the years such as the advent of automated liquid culture systems like the BACTEC® 960 and the MGITTM Tube system, and the development of a myriad of molecular techniques most of which involves nucleic acid amplification (NAA) for the rapid identification of mycobacterial isolates from cultures or even directly from clinical specimens have contributed immensely to the early diagnosis of tuberculosis. Most of these NAA tests are nevertheless fraught with various limitations, thus the search for a rapid, sensitive and specific way of diagnosing tuberculosis is still an active area of research. The search has expanded to areas that would otherwise not have been considered ‘conventional’ in diagnostic mycobacteriology. One of such areas is mass spectrometry. This study joins the relatively few studies of its kind encountered in available literature to establish the ground work for the application of mass spectrometry, specifically Matrix Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-ToF MS) in the field of diagnostic mycobacteriology. This is an area which is in need of the speed, sensitivity and specificity that MALDI-ToF technique promises to offer. Since this technology is still in its infancy, the use of utmost care in the preparation of reagents, and the handling and storage of the organisms used to generate reference mass spectra for the database cannot be overemphasized. Similarly, the optimization of certain crucial experimental factors such as inactivating method and choice of matrix is of paramount importance. The main aim of this thesis was to generate a database of reference mass spectra fingerprints of selected (repository) Mycobacterium species. This necessitated the standardization of an experimental protocol which ensured that experimental factors and the various instrument parameters were optimized for maximum spectra generation and reproducibility. A standard operating procedure (SOP) for generating the database of reference mass spectra finger print of selected Mycobacterium species was developed and used to investigate the ability of the database to differentiate between species belonging to the same clinical disease complex as well as the nontuberculosis complex. The findings of this study imply that if the defined protocol is followed, the database generated has the potential to routinely identify and differentiate (under experimental conditions) more species of Mycobacterium than is currently practical using PCR and its related techniques. It is therefore a realistic expectation that when the database is clinically validated and tested in the next phase of the study, it will contribute immensely to the diagnosis of tuberculosis and other mycobacterioses. It will also aid in the identification of emerging pathogens particularly amongst the non-tuberculous mycobacteria.
Zabet, Moghaddam Masoud. "MALDI mass spectrometry and ionic liquids applications in functional protein analysis /". [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=982074360.
Texto completoDENTI, VANNA. "Development of multi-omic mass spectrometry imaging approaches to assist clinical investigations". Doctoral thesis, Università degli Studi di Milano-Bicocca, 2022. http://hdl.handle.net/10281/365169.
Texto completoThe field of spatial omics defines the gathering of different techniques that allow the detection of significant alterations of biomolecules in the context of their native tissue or cellular structures. As such, they extend the landscape of biological changes occurring in complex and heterogeneous pathological tissues, such as cancer. However, additional molecular levels, such as lipids and glycans, must be studied to define a more comprehensive molecular snapshot of disease and fully understand the complexity and dynamics beyond pathological condition. Among the spatial-omics techniques, matrix-assisted laser desorption/ionisation (MALDI)-mass spectrometry imaging (MSI) offers a powerful insight into the chemical biology of pathological tissues in a multiplexed approach where several hundreds of biomolecules can be examined within a single experiment. Thus, MALDI-MSI has been readily employed for spatial omics studies of proteins, peptides and N-Glycans on clinical formalin-fixed paraffin-embedded (FFPE) tissue samples. Conversely, MALDI-MSI analysis of lipids has always been considered not feasible on FFPE samples due to the loss of a great amount of lipid content during washing steps with organic solvents, with the remaining solvent-resistant lipids being involved in the formalin cross-links. In this three-year thesis work, novel MALDI-MSI approaches for spatial multi-omics analysis on clinical FFPE tissue samples were developed. The first three publications reported in this thesis focused on the development of protocols for MALDI-MSI of lipids in FFPE samples. In particular, two of them describe a sample preparation method for the detection of positively charged phospholipids ions, mainly phosphatidylcholines (PCs), in clinical clear cell Renal Cell Carcinoma (ccRCC) samples and in a xenograft model of breast cancer. The third publication reports the possibility to use negatively charged phospholipids ions, mainly phosphatidylinositols (PIs), to define lipid signatures able to distinguish colorectal cancers with different amount of tumour infiltrating lymphocytes (TILs). The final work proposes a unique multi-omic MALDI-MSI method for the sequential analysis of lipids, N-Glycans and tryptic peptides on a single FFPE section. Specifically, the method feasibility was first established on murine brain technical replicates. The method was consequently used on ccRCC samples, as a proof of concept, assessing a more comprehensive characterisation of the tumour tissue when combining the multi-level molecular information. Altogether, these findings pave the way for new MSI-based spatial multi-omics approach aiming at an extensive and more precise molecular portrait of disease.
Townsend, Shawnda Kristina. "Contemporary rape reportage in The Courier-Mail". Thesis, Queensland University of Technology, 1994. https://eprints.qut.edu.au/36396/1/36396_Townsend_1994.pdf.
Texto completoSMITH, ANDREW JAMES. "MALDI-MSI in the study of glomerulonephritis: Possible molecular indicators of CKD progression". Doctoral thesis, Università degli Studi di Milano-Bicocca, 2017. http://hdl.handle.net/10281/153198.
Texto completoIdiopathic glomerulonephritis (GN), such as membranous nephropathy (MN), focal segmental glomerulosclerosis (FSGS) and IgA nephropathy (IgAN) represent the most frequent primary Glomerular Kidney Diseases (GKDs) worldwide and are a common cause of end-stage renal disease (ESRD). Without the correct diagnosis and, ultimately, the correct selection of therapeutic treatment, the patient has a higher probability of progressing to ESRD and requiring dialysis or transplantation. Although the renal biopsy currently remains the gold standard for the routine diagnosis of idiopathic GN, the invasiveness and difficulty of diagnoses related with this procedure means that there is a strong need for the detection of diagnostic and prognostic biomarkers that can be translated into less invasive diagnostic tools. Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) is a unique proteomic technology that explores the spatial distribution of biomolecules directly in situ, thus integrating molecular and morphological information. The possibility to correlate distribution maps of multiple analyses with histological features makes it an ideal research tool to discover new diagnostic and prognostic markers. This modern proteomic technique could represent an invaluable tool in the field of nephropathology, most specifically in the study of primary glomerulonephritis (GNs), due to its potential to obtain proteomic signatures from pathological glomeruli and tubuli. The body of work enclosed in this thesis follows the application of MALDI-MSI to fresh-frozen and formalin-fixed paraffin-embedded (FFPE) renal biopsies in order to detect diagnostic and prognostic molecular markers associated with the most common forms of glomerulonephritis. More specifically, MALDI-MSI was applied to fresh frozen bioptic renal tissue from patients with a histological diagnosis of FSGS (n=6), IgAN, (n=6) and MN (n=7), and from controls (n=4) in order to detect specific molecular signatures of primary glomerulonephritis. MALDI-MSI was able to generate molecular signatures capable to distinguish between normal kidney and pathological GN, with specific signals (m/z 4025, 4048 and 4963) representing potential indicators of CKD development. Moreover, specific disease-related signatures (m/z 4025 and 4048 for FSGS, m/z 4963 and 5072 for IgAN) were detected. Of these signals, m/z 4048 was identified as α-1-antitrypsin (A1AT) and was shown to be localised to the podocytes within sclerotic glomeruli by immunohistochemistry and could potentially be one of the markers of podocyte stress that is correlated with the development of FSGS. Furthermore, a protocol for the analysis of FFPE renal biopsies was developed and optimised. Using this optimised protocol, MALDI-MSI was applied to renal biopsies from histologically diagnosed primary and secondary MN patients (n=20) in order to evaluate the capability of this technology to detect alterations in their tissue proteome. MALDI-MSI was able to generate molecular signatures of primary and secondary MN, with one particular signal (m/z 1459), identified as Serine/threonine-protein kinase MRCK gamma, being over-expressed in the glomeruli of primary MN patients with respect to secondary MN. Furthermore, this proteomic approach detected a number of signals that could differentiate the different forms of iMN (m/z 1094, 1116, 1381 and 1459). These signals could potentially represent future targets to be investigated as proteomic markers for the further stratification of iMN patients. The findings presented here highlight how the study of glomerular diseases using this modern proteomic technology shows vast potential and may eventually herald an era where these findings are translated for use within a clinical context, either for diagnostic or prognostic purposes.
Balluff, Benjamin. "MALDI imaging mass spectrometry in clinical proteomics research of gastric cancer tissues". Diss., lmu, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-155986.
Texto completoFlatley, Brian. "Utilisation of mass spectrometry in the quest for male urogenital cancer biomarkers". Thesis, University of Reading, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.632862.
Texto completoDjidja, Marie-Claude. "Examination of tumour tissues by direct MALDI-mass spectrometry imaging and profiling". Thesis, Sheffield Hallam University, 2009. http://shura.shu.ac.uk/20662/.
Texto completoTummala, Manorama. "Surfactant-Aided Matrix Assisted Laser Desorption/Ionization Mass Spectrometry (SA-MALDI MS)". University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1100672049.
Texto completoBroscoe, Molly. "`Who’s the Alpha Male Now Bitches’: Masculinity Narratives in Mass Murder Manifestos". University of Cincinnati / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1626357258853525.
Texto completoSaraiva, Bruno Manuel Santos. "Identification of bacteria by mass spectrometry". Master's thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/14317.
Texto completoIdentification of bacteria is a major part of the diagnosis of a pathogenic infection. In order to positively and confidently identify the bacteria, different techniques can be applied. These techniques are based on different principles, such as phenotypic differences, DNA sequences comparison, mass spectrometry (MALDI-TOF) and the protein content of the bacteria. From comparison of MALDI-TOF for bacteria identification with the other methodologies available, several advantages can be highlighted: lower cost per identification, faster results and higher discrimination power. This work focus on the development of a new application capable of identifying bacteria using MALDI-TOF mass spectrometry. It started by the protein extraction of the samples and the acquisition of the mass profiles of those bacteria. This work proceeded with the development of an application to identify bacteria by comparing the mass profile of an unknown sample with the mass profiles of the bacteria in our database. Using the developed application it was possible to identify both Gram-positive and Gram-negative bacteria to the strain-level. When an identification to strain-level was not possible, it was possible to identify the bacteria to the species-level and in the case the database did not contain an entry of the same species as the sample, the score values were low enough to disregard a possible identification resulting in a low false-positive rate.
A identificação de bactérias é um dos principais componentes do diagnóstico de infeções patogénicas. De modo a se conseguir obter uma identificação podem ser aplicadas diferentes técnicas, tais como, diferenças de fenótipo, comparação de sequências de ADN e a comparação do conteúdo proteico das bactérias. Quando se compara a identificação bacteriana com recurso à espectrometria de massa MALDI-TOF com as metodologias alternativas, podemos destacar diversas vantagens: menor custo por análise, menos tempo para obtenção de resultados e um maior poder discriminatório. Este trabalho tem como foco o desenvolvimento de uma nova aplicação capaz de identificar bactérias com recurso a espectrometria de massa. O trabalho foi iniciado com a extração proteica das amostras e a aquisição dos perfis de massa dessas bactérias. De seguida, prosseguiu-se com o desenvolvimento de uma aplicação para a identificação de bactérias com base na comparação dos perfis de massa da amostra e dos perfis contidos na base de dados. Usando a aplicação desenvolvida conseguiu-se identificar corretamente tanto bactérias Gram-positivas como Gram-negativas. Quando uma identificação da estirpe não foi possível, a aplicação permitiu a identificação da espécie bacteriana e no caso de a base de dados não conter nenhuma entrada que correspondesse a estirpe ou espécie da amostra, os scores obtidos eram suficientemente baixos para uma eventual identificação ser descartada, resultando assim numa baixa taxa de falsos positivos.
IVANOVA, MARIIA. "Advanced proteomics MALDI-MSI imaging in chronic glomerulonephrites: from diagnostics to precision medicine". Doctoral thesis, Università degli Studi di Milano-Bicocca, 2020. http://hdl.handle.net/10281/263391.
Texto completoChronical kidney disease (CKD) is a worldwide health problem with increasing incidence, where the major part accounts for chronic glomerulonephrites (GN). It is a group of diseases of various aetiology and multiform clinical course, having various prognosis which is often hardly predictable as well as existing prognostic markers are not always certain. There is an urging need of new reliable and specific prognostic and therapeutic markers research. A modern proteomic technology - Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) has been employed in many GN studies showing promising results. We aimed to study several forms of primary and secondary glomerulonephrites (membranous nephropathy, IgA nephropathy, diabetic nephropathy) to enlighten possible molecular alterations significant of diseases’ progression. The studies were performed on renal tissue biopsies, analysing them with high spatial resolution MALDI-MSI to get better visualisation of signals’ co-localisation on tissue. We performed a comparison of molecular profiles of various forms of GN. As a result, we were able to generate and distinguish specific tryptic peptides profiles of different cell regions (tubules, glomeruli, interstitium, connective tissue) and detect proteins with an altered intensity, implicated in inflammatory and healing pathways. MALDI-MSI, being able to define renal structures, could provide additional diagnostic and prognostic information. Generation of collective diagnostic panels may fulfil our pathogenesis understanding and assist clinical prognostic assessment.
PENG, LIJUAN. "MATRIX-ASSISTED LASER DESORPTION/IONIZATION (MALDI) TARGET MODIFICATION FOR ENHANCED PROTEOMICS ANALYSIS AND PLASMA POLYMER CHARACTERIZATION BY MALDI MASS SPECTROMETRY". OpenSIUC, 2010. https://opensiuc.lib.siu.edu/dissertations/207.
Texto completoScionti, Vincenzo. "Novel Applications of Mass Spectrometry on Synthetic Polymeric Materials". University of Akron / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=akron1335149657.
Texto completoBowman, Amber Suzanne. "ENHANCED ANALYSIS OF LIGNIN DEHYDROGENATION OLIGOMERS VIA MASS SPECTROMETRY". UKnowledge, 2018. https://uknowledge.uky.edu/chemistry_etds/104.
Texto completoMyatt, Christopher Paul. "The development of a matrix-assisted laser desorption/chemical ionisation time-of-flight mass spectrometer". Thesis, University of Warwick, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340903.
Texto completoHoteling, Andrew J. "MALD/I TOF PSD and CID : understanding precision, resolution, and mass accuracy and MALD/I TOFMS : investigation of discrimination issues related to solubility /". Philadelphia, Pa. : Drexel University, 2004. http://dspace.library.drexel.edu/handle/1860/318.
Texto completoEriksson, Mikaela. "Conflict-related sexual violence against men: A thematic analysis of the phenomenon in mass media". Thesis, Linnéuniversitetet, Institutionen för samhällsstudier (SS), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-100248.
Texto completoBroberg, Susanna. "Studies of oligo- and polysaccharides by MALDI-TOF and ESI-ITMSn mass spectrometry /". Uppsala : Dept. of Chemistry, Swedish Univ. of Agricultural Sciences, 2004. http://epsilon.slu.se/a452.pdf.
Texto completoMaurer, Katja. "Oral brush biopsy analysis by MALDI-ToF Mass Spectrometry for early cancer diagnosis". Doctoral thesis, Universitätsbibliothek Leipzig, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-116691.
Texto completoWilliams, Bradley Allen. "LOCATING CHELERYTHRINE, AN ALKALOID, WITHIN A CYTOSOLIC ENVIRONMENT BY MALDI-TOF MASS SPECTROMETRY". Wright State University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=wright1389645518.
Texto completoAboulmagd, Khodier Sarah. "Analysis of Lipids in Kidney Tissue Using High Resolution MALDI Mass Spectrometry Imaging". Doctoral thesis, Humboldt-Universität zu Berlin, 2018. http://dx.doi.org/10.18452/19443.
Texto completoMass spectrometry imaging is indispensable for studying the spatial distribution of molecules within a diverse range of biological samples. Since its introduction, MALDI has become a dominant imaging method, which proved useful to sort out the complexity of lipid structures in biological tissues. The role of cisplatin in the treatment of human malignancies is well-established. However, nephrotoxicity is a limiting side effect that involves an acute injury of the proximal tubule and alterations in the renal lipid profile. This evolved the motivation to study the spatial distribution of lipids in the kidney tissue of cisplatin-treated rats to shed light on the lipid signaling pathways involved. A method for mapping of lipid distributions in kidney sections using MALDI-LTQ-Orbitrap was developed, utilizing the high performance of orbitrap detection. The distribution of kidney lipids in cisplatin-treated samples revealed clear differences with respect to control group, which could be correlated to the proximal tubule injury. The findings highlight the usefulness of MALDI MSI as complementary tool for clinical diagnostics. Furthermore, assessment of the ion images of lipids in cisplatin-treated kidney mostly considered qualitative aspects. Relative quantitative comparisons were limited by the variable influence of experimental and instrumental conditions. Hence, the necessity developed to establish a normalization method allowing comparison of lipid intensity in MALDI imaging measurements of different samples. The method employed an inkjet printer to apply a mixture of the MALDI matrix and dual lipid-metal internal standards. Using ICP-MS, the metal internal standard allowed to confirm the consistency of the matrix and internal standards application. Applying the method to normalize ion intensities of kidney lipids demonstrated excellent image correction and successfully enabled relative quantitative comparison of lipid images in control and cisplatin-treated samples.
Page, Jennifer Renee'. "'And he shall be called woman': behind the mask of selected black male actors cross-dressing in entertainment". DigitalCommons@Robert W. Woodruff Library, Atlanta University Center, 2009. http://digitalcommons.auctr.edu/dissertations/98.
Texto completoEastwood, Stephanie. "Development of Amine Containing Polymer Modified MALDI Targets for Complex Peptide and Protein Mixture Fractionation Prior to MALDI Mass Spectrometry Analysis". OpenSIUC, 2014. https://opensiuc.lib.siu.edu/dissertations/948.
Texto completoHunsucker, Stephen Warren. "Time-of-Flight Mass Spectrometry to Characterize Inorganic Coordination Complexes and Cyanobacteria". Diss., Virginia Tech, 2001. http://hdl.handle.net/10919/27150.
Texto completoPh. D.
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