Literatura académica sobre el tema "LT γδ"
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Artículos de revistas sobre el tema "LT γδ"
Alonso, Sara, Luo Jia, Alyssa Laguerta y Karen Edelblum. "Expansion of the intraepithelial lymphocyte (IEL) compartment results in an increased bioenergetic profile and reduced IFNγ production in γδ IELs." Journal of Immunology 210, n.º 1_Supplement (1 de mayo de 2023): 150.20. http://dx.doi.org/10.4049/jimmunol.210.supp.150.20.
Texto completoFischer, Matthew, Luo Jia y Karen Edelblum. "T cell receptor signaling mediates enhanced IFNγ production by γδ intraepithelial lymphocytes in response to type I interferon". Journal of Immunology 210, n.º 1_Supplement (1 de mayo de 2023): 150.19. http://dx.doi.org/10.4049/jimmunol.210.supp.150.19.
Texto completoHu, Yongxian, Yanjun Gu, Lixia Sheng, Huarui Fu, Kangni Wu, Lifei Zhang, Lizhen Liu et al. "Decitabine Can Increase the Induction of Regulatory γδ T Cells with Enhanced Immunosuppression on Graft-Versus-Host Disease From Adult Human Peripheral Blood Mononuclear Cells". Blood 118, n.º 21 (18 de noviembre de 2011): 1901. http://dx.doi.org/10.1182/blood.v118.21.1901.1901.
Texto completoFischer, Matthew, Luo Jia y Karen L. Edelblum. "Type I interferon enhances γδ intraepithelial lymphocyte migratory behavior via CD47 upregulation". Journal of Immunology 206, n.º 1_Supplement (1 de mayo de 2021): 17.17. http://dx.doi.org/10.4049/jimmunol.206.supp.17.17.
Texto completoKimura, Shunsuke, Petri Pölönen, Lindsey Montefiori, Kenneth Caldwell, Ilaria Iacobucci, Chelsey Chen, Anthony Brown et al. "STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young". Blood 142, Supplement 1 (28 de noviembre de 2023): 845. http://dx.doi.org/10.1182/blood-2023-178688.
Texto completoLiang, Shuang, Jiangying Liu, Haitao Gao, Ruoyang Liu, Ning Wu, Tianhui Dong y Xiaojun Huang. "Induced CD25+CD127dim Γδ Tregs in Acute Myeloid Leukemia Suppress the Activity of Normal Αβ T Cells". Blood 136, Supplement 1 (5 de noviembre de 2020): 27–28. http://dx.doi.org/10.1182/blood-2020-136541.
Texto completoSilva, Polyana Barbosa, Márcia Antoniazi Michelin, Millena Prata Jammal y Eddie Fernando Cândido Murta. "Immunological Characteristics between αβ TDC and γδ TDC Cells in the Spleen of Breast Cancer-Induced Mice". Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics 43, n.º 05 (mayo de 2021): 368–73. http://dx.doi.org/10.1055/s-0041-1730286.
Texto completoMaeda, Yoshinobu, Pavan Reddy, Kathleen P. Lowler, Chen Liu, Dennis Keith Bishop y James L. M. Ferrara. "Critical role of host γδ T cells in experimental acute graft-versus-host disease". Blood 106, n.º 2 (15 de julio de 2005): 749–55. http://dx.doi.org/10.1182/blood-2004-10-4087.
Texto completoBoissière-Michot, Florence, Ghita Chabab, Caroline Mollevi, Séverine Guiu, Evelyne Lopez-Crapez, Jeanne Ramos, Nathalie Bonnefoy, Virginie Lafont y William Jacot. "Clinicopathological Correlates of γδ T Cell Infiltration in Triple-Negative Breast Cancer". Cancers 13, n.º 4 (12 de febrero de 2021): 765. http://dx.doi.org/10.3390/cancers13040765.
Texto completoTuengel, Jessica, Sanya Ranchal, Alexandra Maslova, Gurpreet Aulakh, Maria Papadopoulou, Sibyl Drissler, Bing Cai et al. "Characterization of Adaptive-like γδ T Cells in Ugandan Infants during Primary Cytomegalovirus Infection". Viruses 13, n.º 10 (3 de octubre de 2021): 1987. http://dx.doi.org/10.3390/v13101987.
Texto completoTesis sobre el tema "LT γδ"
Chabab, Ghita. "Caractérisation d'une sous-population de LT γδ régulateurs dans les cancers solides humains". Electronic Thesis or Diss., Université de Montpellier (2022-....), 2022. http://www.theses.fr/2022UMONT067.
Texto completoΓδ T cells contribute to the anti-tumor immunity within the tumor microenvironment in various cancers. Despite their well-described effector functions, recent studies correlated their presence in the tumor microenvironment with solid tumor progression suggesting that γδ T cells may display pro-tumor activities. My project aimed to characterize those regulatory γδ T cells and decipher their role in cancer.We demonstrated in vitro that inflammatory signals promote the development of a regulatory γδ T cell sub-population characterized by the expression of CD73 and displaying immunosuppressive functions through the production of immunosuppressive molecules such as IL-10, adenosine and the angiogenic and chemotactic factor IL-8. The challenge associated with the characterization of CD73+ γδ T cells resides in assessing their existence in vivo as well as their relevance in human cancers. We showed in human breast cancer that ~20% of tumor infiltrating γδ T lymphocytes (TILs) expressed CD73 and displayed the same immunosuppressive functions as described in vitro, suggesting that they could promote tumor development via these mechanisms. In line with these observations, we showed that the presence of γδ TILs is associated with late tumor grades in breast cancer. We extended such observations to ovarian cancer and showed that the density of CD73+ γδ TILs negatively correlates with patient survival, suggesting that CD73+ γδ TILs density could be used as a prognosis factor. Using Imaging by Mass Cytometry, we investigated the cellular networks of regulatory γδ TILs (CD73+) and their effector counterpart (CD73-) in breast and ovarian tumors to better understand their role in cancer. Our data show different ecosystems for CD73+ compared to CD73- γδ TILs reinforcing the idea that CD73+ and CD73- γδ T cells are functionally different.Altogether, these data improve our knowledge on human γδ T cell biology during cancer development, with the in-depth characterization of the new regulatory γδ T cell subset, their localization and their functions within the tumor microenvironment