Artículos de revistas sobre el tema "LKB1/mTOR"
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Xiong, Yan, Ziye Xu, Yizhen Wang, Shihuan Kuang y Tizhong Shan. "Adipocyte-specific DKO of Lkb1 and mTOR protects mice against HFD-induced obesity, but results in insulin resistance". Journal of Lipid Research 59, n.º 6 (10 de abril de 2018): 974–81. http://dx.doi.org/10.1194/jlr.m081463.
Texto completoJiang, Wenxiao, Yijun Zhang, Ye Huang, Yunfeng Cheng y Zhigang Liu. "Effect of Hepatic Kinase B1 (LKB1) on Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells During Senescence". Journal of Biomaterials and Tissue Engineering 10, n.º 2 (1 de febrero de 2020): 246–51. http://dx.doi.org/10.1166/jbt.2020.2247.
Texto completoYilmaz, Emrullah, Lauren Averett Byers, Lixia Diao, Uma Giri, Jayanthi Gudikote, You Hong Fan, Jing Wang et al. "Use of proteomic analysis of LKB1/AMPK/mTOR pathways to identify IGF-1R pathway upregulation with LKB1 loss or mTOR inhibition in NSCLC: Implications for targeted combinations." Journal of Clinical Oncology 30, n.º 15_suppl (20 de mayo de 2012): 10612. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.10612.
Texto completoNishimura, Sadaaki, Masakazu Yashiro, Tomohiro Sera, Yurie Yamamoto, Yukako Kushitani, Atsushi Sugimoto, Shuhei Kushiyama et al. "Serine threonine kinase 11/liver kinase B1 mutation in sporadic scirrhous-type gastric cancer cells". Carcinogenesis 41, n.º 11 (31 de marzo de 2020): 1616–23. http://dx.doi.org/10.1093/carcin/bgaa031.
Texto completoPaunovic, Verica, Stojan Peric, Irena Vukovic, Marina Stamenkovic, Emina Milosevic, Danijela Stevanovic, Milos Mandic et al. "Downregulation of LKB1/AMPK Signaling in Blood Mononuclear Cells Is Associated with the Severity of Guillain–Barre Syndrome". Cells 11, n.º 18 (16 de septiembre de 2022): 2897. http://dx.doi.org/10.3390/cells11182897.
Texto completoYang, Jing, Chengxian Xu, Joseph Lechner, Haley Walls y Kai Yang. "LKB1 regulates macrophage metabolism and functional polarization in immunomodulation". Journal of Immunology 210, n.º 1_Supplement (1 de mayo de 2023): 168.14. http://dx.doi.org/10.4049/jimmunol.210.supp.168.14.
Texto completoZhou, Wei, Adam I. Marcus y Paula M. Vertino. "Dysregulation of mTOR activity through LKB1 inactivation". Chinese Journal of Cancer 32, n.º 8 (5 de agosto de 2013): 427–33. http://dx.doi.org/10.5732/cjc.013.10086.
Texto completoBorkowsky, Sarah, Maximilian Gass, Azadeh Alavizargar, Johannes Hanewinkel, Ina Hallstein, Pavel Nedvetsky, Andreas Heuer y Michael P. Krahn. "Phosphorylation of LKB1 by PDK1 Inhibits Cell Proliferation and Organ Growth by Decreased Activation of AMPK". Cells 12, n.º 5 (6 de marzo de 2023): 812. http://dx.doi.org/10.3390/cells12050812.
Texto completoRadu, Anca G., Sakina Torch, Florence Fauvelle, Karin Pernet-Gallay, Anthony Lucas, Renaud Blervaque, Véronique Delmas et al. "LKB1 specifies neural crest cell fates through pyruvate-alanine cycling". Science Advances 5, n.º 7 (julio de 2019): eaau5106. http://dx.doi.org/10.1126/sciadv.aau5106.
Texto completoLi, Yongqiang, Tao Sun, Shuxin Shen, Lixia Wang y Jifeng Yan. "LncRNA DYNLRB2-2 inhibits THP-1 macrophage foam cell formation by enhancing autophagy". Biological Chemistry 400, n.º 8 (26 de julio de 2019): 1047–57. http://dx.doi.org/10.1515/hsz-2018-0461.
Texto completoWang, Yuan, Shan Zhu, Hongtao Liu, Wen Wei, Yi Tu, Chuang Chen, Junlong Song et al. "Thyroxine Alleviates Energy Failure, Prevents Myocardial Cell Apoptosis, and Protects against Doxorubicin-Induced Cardiac Injury and Cardiac Dysfunction via the LKB1/AMPK/mTOR Axis in Mice". Disease Markers 2019 (18 de diciembre de 2019): 1–10. http://dx.doi.org/10.1155/2019/7420196.
Texto completoAkasaka, Yasuyuki, Shun Hasei, Yukino Ohata, Machi Kanna, Yusuke Nakatsu, Hideyuki Sakoda, Midori Fujishiro et al. "Auraptene Enhances AMP-Activated Protein Kinase Phosphorylation and Thereby Inhibits the Proliferation, Migration and Expression of Androgen Receptors and Prostate-Specific Antigens in Prostate Cancer Cells". International Journal of Molecular Sciences 24, n.º 21 (6 de noviembre de 2023): 16011. http://dx.doi.org/10.3390/ijms242116011.
Texto completoShaw, Reuben J., Nabeel Bardeesy, Brendan D. Manning, Lyle Lopez, Monica Kosmatka, Ronald A. DePinho y Lewis C. Cantley. "The LKB1 tumor suppressor negatively regulates mTOR signaling". Cancer Cell 6, n.º 1 (julio de 2004): 91–99. http://dx.doi.org/10.1016/j.ccr.2004.06.007.
Texto completoLee, H. R., J. Kim, S. J. Yoo, J. A. Park y S. W. Kang. "POS0005 THE EFFECT OF LKB1 INHIBITION IN RA PATHOGENESIS". Annals of the Rheumatic Diseases 80, Suppl 1 (19 de mayo de 2021): 204.3–204. http://dx.doi.org/10.1136/annrheumdis-2021-eular.946.
Texto completoAznar, Nicolas y Marc Billaud. "Primary Cilia Bend LKB1 and mTOR to Their Will". Developmental Cell 19, n.º 6 (diciembre de 2010): 792–94. http://dx.doi.org/10.1016/j.devcel.2010.11.016.
Texto completoZhao, Jimeng, Zhe Ma, Handan Zheng, Yan Huang, Luyi Wu, Huangan Wu, Yin Shi, Huirong Liu y Yanan Liu. "Effects of Herb-Partitioned Moxibustion on Autophagy and Immune Activity in the Colon Tissue of Rats with Crohn’s Disease". Evidence-Based Complementary and Alternative Medicine 2022 (28 de enero de 2022): 1–12. http://dx.doi.org/10.1155/2022/3534874.
Texto completoXu, Ziye, Wenjing You, Fengqin Wang, Yizhen Wang y Tizhong Shan. "Elucidating the role of Lkb1 and mTOR in adipose tissue". Adipocyte 8, n.º 1 (20 de octubre de 2018): 26–30. http://dx.doi.org/10.1080/21623945.2018.1535743.
Texto completoTreilleux, Isabelle, Monica Arnedos, Claire Cropet, Jean-Marc Ferrero, Sophie Abadie Lacourtoisie, Dominique Spaeth, Christelle Levy et al. "Predictive markers of everolimus efficacy in hormone receptor positive (HR+) metastatic breast cancer (MBC): Final results of the TAMRAD trial translational study." Journal of Clinical Oncology 31, n.º 15_suppl (20 de mayo de 2013): 510. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.510.
Texto completoHuang, Xu, Stephan Wullschleger, Natalia Shpiro, Victoria A. McGuire, Kei Sakamoto, Yvonne L. Woods, Wendy Mcburnie, Stewart Fleming y Dario R. Alessi. "Important role of the LKB1–AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice". Biochemical Journal 412, n.º 2 (14 de mayo de 2008): 211–21. http://dx.doi.org/10.1042/bj20080557.
Texto completoSun, Gao, Andrei I. Tarasov, James A. McGinty, Paul M. French, Angela McDonald, Isabelle Leclerc y Guy A. Rutter. "LKB1 deletion with the RIP2.Cre transgene modifies pancreatic β-cell morphology and enhances insulin secretion in vivo". American Journal of Physiology-Endocrinology and Metabolism 298, n.º 6 (junio de 2010): E1261—E1273. http://dx.doi.org/10.1152/ajpendo.00100.2010.
Texto completoBi, Chengfeng, Chunsun Jiang, Xiaoxing Jiang, Xin Huang, Mario R. Fernandez, Javeed Iqbal, Robert E. Lewis, Wing Chung Chan, Timothy McKeithan y Kai Fu. "The Mir-17∼92 Cluster Activates mTORC1 Signaling in MCL by Targeting Multiple Regulators of the LKB1/AMPK/mTOR Pathway". Blood 120, n.º 21 (16 de noviembre de 2012): 5118. http://dx.doi.org/10.1182/blood.v120.21.5118.5118.
Texto completoHan, Dong, Shao-Jun Li, Yan-Ting Zhu, Lu Liu y Man-Xiang Li. "LKB1/AMPK/mTOR Signaling Pathway in Non-small-cell Lung Cancer". Asian Pacific Journal of Cancer Prevention 14, n.º 7 (30 de julio de 2013): 4033–39. http://dx.doi.org/10.7314/apjcp.2013.14.7.4033.
Texto completoJiménez-Mora, Eva, Beatriz Gallego, Sergio Díaz-Gago, Marina Lasa, Pablo Baquero y Antonio Chiloeches. "V600EBRAF Inhibition Induces Cytoprotective Autophagy through AMPK in Thyroid Cancer Cells". International Journal of Molecular Sciences 22, n.º 11 (3 de junio de 2021): 6033. http://dx.doi.org/10.3390/ijms22116033.
Texto completoXiao, Jia, Rui Guo, Man-Lung Fung, Emily C. Liong, Raymond Chuen Chung Chang, Yick-Pang Ching y George L. Tipoe. "Garlic-Derived S-Allylmercaptocysteine Ameliorates Nonalcoholic Fatty Liver Disease in a Rat Model through Inhibition of Apoptosis and Enhancing Autophagy". Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/642920.
Texto completoTzatsos, Alexandros y Konstantin V. Kandror. "Nutrients Suppress Phosphatidylinositol 3-Kinase/Akt Signaling via Raptor-Dependent mTOR-Mediated Insulin Receptor Substrate 1 Phosphorylation". Molecular and Cellular Biology 26, n.º 1 (1 de enero de 2006): 63–76. http://dx.doi.org/10.1128/mcb.26.1.63-76.2006.
Texto completoShaw, R. J. "LKB1 and AMP-activated protein kinase control of mTOR signalling and growth". Acta Physiologica 196, n.º 1 (mayo de 2009): 65–80. http://dx.doi.org/10.1111/j.1748-1716.2009.01972.x.
Texto completoGreen, Alexa S., Nicolas Chapuis, Thiago Trovati Maciel, Lise Willems, Mireille Lambert, Christophe Arnoult, Olivier Boyer et al. "The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation". Blood 116, n.º 20 (18 de noviembre de 2010): 4262–73. http://dx.doi.org/10.1182/blood-2010-02-269837.
Texto completoMoore, Timothy M., Xavier M. Mortensen, Conrad K. Ashby, Alexander M. Harris, Karson J. Kump, David W. Laird, Aaron J. Adams, Jeremy K. Bray, Ting Chen y David M. Thomson. "The effect of caffeine on skeletal muscle anabolic signaling and hypertrophy". Applied Physiology, Nutrition, and Metabolism 42, n.º 6 (junio de 2017): 621–29. http://dx.doi.org/10.1139/apnm-2016-0547.
Texto completoLemoine, Manuela, Enrico Derenzini, Daniela Buglio, L. Jeffrey Medeiros, R. Eric Davis, Jiexin Zhang, Yuan Ji y Anas Younes. "The pan-deacetylase inhibitor panobinostat induces cell death and synergizes with everolimus in Hodgkin lymphoma cell lines". Blood 119, n.º 17 (26 de abril de 2012): 4017–25. http://dx.doi.org/10.1182/blood-2011-01-331421.
Texto completoJung, Taek-Yeol, Jae-Eun Ryu, Mi-Mi Jang, Soh-Yeon Lee, Gyu-Rin Jin, Chan-Woo Kim, Chae-Young Lee et al. "Naa20, the catalytic subunit of NatB complex, contributes to hepatocellular carcinoma by regulating the LKB1–AMPK–mTOR axis". Experimental & Molecular Medicine 52, n.º 11 (noviembre de 2020): 1831–44. http://dx.doi.org/10.1038/s12276-020-00525-3.
Texto completoColombo, Marika, Matteo Demetrio Tripodi, Gabriel Caso, Elisa Perin, Mirko Marabese, Massimo Broggini y Elisa Caiola. "Abstract 6346: Identification of ERK inhibitor-based combinations targeting LKB1-mutated NSCLC". Cancer Research 82, n.º 12_Supplement (15 de junio de 2022): 6346. http://dx.doi.org/10.1158/1538-7445.am2022-6346.
Texto completoYang, Cong, Hongyu Ding, Yang Yang, Long Yang, Yun Yang, Meimiao Fang, Jin Ren, Ronggui Hu, Chengcheng Wang y Wujun Geng. "BAP1 regulates AMPK-mTOR signalling pathway through deubiquitinating and stabilizing tumour-suppressor LKB1". Biochemical and Biophysical Research Communications 529, n.º 4 (septiembre de 2020): 1025–32. http://dx.doi.org/10.1016/j.bbrc.2020.05.223.
Texto completoRegina, Sandra, Jean-Baptiste Valentin, Sébastien Lachot, Bruno Giraudeau, Jerome Rollin y Yves Gruel. "Alterations of P53 and PTEN Genes Are Associated with Increased TF Expression and Reduced Survival in Non Small Cell Lung Cancer". Blood 112, n.º 11 (16 de noviembre de 2008): 1032. http://dx.doi.org/10.1182/blood.v112.11.1032.1032.
Texto completoTsai, Hui-Jen, Tsung-Ming Chang, Yan-Shen Shan, Pei-Yi Chu, Shih Sheng Jiang, Wen-Chun Hung, Yu-Lin Chen, Hsu-Chi Tu y Li-Tzong Chen. "The regulatory role of PTEN and LKB1 on mTOR pathway in pancreatic neuroendocrien tumors". Pancreatology 17, n.º 3 (julio de 2017): S11. http://dx.doi.org/10.1016/j.pan.2017.05.035.
Texto completoGreen, Alexa S., Nicolas Chapuis, Catherine Lacombe, Patrick Mayeux, Didier Bouscary y Jerome Tamburini. "LKB1/AMPK/mTOR signaling pathway in hematological malignancies: From metabolism to cancer cell biology". Cell Cycle 10, n.º 13 (julio de 2011): 2115–20. http://dx.doi.org/10.4161/cc.10.13.16244.
Texto completoLazo-de-la-Vega-Monroy, Maria-Luisa, Karen-Alejandra Mata-Tapia, Juan-Antonio Garcia-Santillan, Maria-Angelica Corona-Figueroa, Martha-Isabel Gonzalez-Dominguez, Hector-Manuel Gomez-Zapata, Juan-Manuel Malacara, Leonel Daza-Benitez y Gloria Barbosa-Sabanero. "Association of placental nutrient sensing pathways with birth weight". Reproduction 160, n.º 3 (septiembre de 2020): 455–68. http://dx.doi.org/10.1530/rep-20-0186.
Texto completoÁvalos, Yenniffer, Jimena Canales, Roberto Bravo-Sagua, Alfredo Criollo, Sergio Lavandero y Andrew F. G. Quest. "Tumor Suppression and Promotion by Autophagy". BioMed Research International 2014 (2014): 1–15. http://dx.doi.org/10.1155/2014/603980.
Texto completoTanwar, Pradeep S., Tomoko Kaneko-Tarui, LiHua Zhang y Jose M. Teixeira. "Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesis". Human Molecular Genetics 21, n.º 20 (12 de julio de 2012): 4394–405. http://dx.doi.org/10.1093/hmg/dds272.
Texto completoLiemburg-Apers, Dania C., Jori A. L. Wagenaars, Jan A. M. Smeitink, Peter H. G. M. Willems y Werner J. H. Koopman. "Acute stimulation of glucose influx upon mitoenergetic dysfunction requires LKB1, AMPK, Sirt2 and mTOR–RAPTOR". Journal of Cell Science 129, n.º 23 (28 de octubre de 2016): 4411–23. http://dx.doi.org/10.1242/jcs.194480.
Texto completoVila-Bedmar, Rocio, Margarita Lorenzo y Sonia Fernández-Veledo. "Adenosine 5′-Monophosphate-Activated Protein Kinase-Mammalian Target of Rapamycin Cross Talk Regulates Brown Adipocyte Differentiation". Endocrinology 151, n.º 3 (4 de febrero de 2010): 980–92. http://dx.doi.org/10.1210/en.2009-0810.
Texto completoShackelford, D. B., D. S. Vasquez, J. Corbeil, S. Wu, M. Leblanc, C. L. Wu, D. R. Vera y R. J. Shaw. "mTOR and HIF-1 -mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome". Proceedings of the National Academy of Sciences 106, n.º 27 (18 de junio de 2009): 11137–42. http://dx.doi.org/10.1073/pnas.0900465106.
Texto completoDong, Li-xia, Lin-lin Sun, Xia Zhang, Li Pan, Lin-juan Lian, Zhe Chen y Dian-sheng Zhong. "Negative regulation of mTOR activity by LKB1-AMPK signaling in non-small cell lung cancer cells". Acta Pharmacologica Sinica 34, n.º 2 (26 de noviembre de 2012): 314–18. http://dx.doi.org/10.1038/aps.2012.143.
Texto completoWildenberg, Manon, Anne Christine Vos, Marjolijn Duijvestein, Auke P. Verhaar, Daniel W. Hommes y Gijs R. van den Brink. "Tu1945 Induction of Autophagy Upon DC-T Cell Contact is Mediated by LKB1-AMPK-mTOR Signalling". Gastroenterology 142, n.º 5 (mayo de 2012): S—884. http://dx.doi.org/10.1016/s0016-5085(12)63432-5.
Texto completoWildenberg, M. E., A. C. Vos, M. Duijvestein, A. Verhaar, G. van den Brink y D. W. Hommes. "OP03 Induction of autophagy upon DC-T cell contact is mediated by LKB1 AMPK mTOR signalling". Journal of Crohn's and Colitis 6 (febrero de 2012): S2. http://dx.doi.org/10.1016/s1873-9946(12)60004-x.
Texto completoHan, Jie, Huimin Liang, Derun Tian, Jianying Du, Qiming Wang, Pengjiao Xi, Haomin Wang y Yongmei Li. "mTOR remains unchanged in diet-resistant (DR) rats despite impaired LKB1/AMPK cascade in adipose tissue". Biochemical and Biophysical Research Communications 476, n.º 4 (agosto de 2016): 333–39. http://dx.doi.org/10.1016/j.bbrc.2016.05.123.
Texto completoBorthakur, Gautam, Michael Andreeff, Kevin R. Coombes, Yi Hua Qiu, Seshagiri Duvvuri, Nianxiang Zhang, Vivian Ruvolo et al. "High Expression of Autophagy Related Proteins Negatively Impacts Clinical Outcomes in Acute Myelogenous Leukemia–Time to Target Autophagy to Improve Therapy Outcomes?" Blood 118, n.º 21 (18 de noviembre de 2011): 2513. http://dx.doi.org/10.1182/blood.v118.21.2513.2513.
Texto completoHou, Yawei, Yameng Li, Yichuan Wang, Wenpu Li y Zhenwei Xiao. "Screening and Analysis of Key Genes in miRNA-mRNA Regulatory Network of Membranous Nephropathy". Journal of Healthcare Engineering 2021 (16 de noviembre de 2021): 1–13. http://dx.doi.org/10.1155/2021/5331948.
Texto completoGoel, MadhuMati, Annu Makker, AbbasAli Mahdi, Vikram Bhatia, Vinita Das, Anjoo Agarwal y Amita Pandey. "PI3K/Akt/mTOR signaling & its regulator tumour suppressor genes PTEN & LKB1 in human uterine leiomyomas". Indian Journal of Medical Research 143, n.º 7 (2016): 112. http://dx.doi.org/10.4103/0971-5916.191808.
Texto completoNguyen, H. B., J. T. Babcock, C. D. Wells y L. A. Quilliam. "LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap". Oncogene 32, n.º 35 (1 de octubre de 2012): 4100–4109. http://dx.doi.org/10.1038/onc.2012.431.
Texto completoLai, L. P., B. N. Lilley, J. R. Sanes y A. P. McMahon. "Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation". Proceedings of the National Academy of Sciences 110, n.º 48 (11 de noviembre de 2013): 19450–55. http://dx.doi.org/10.1073/pnas.1309001110.
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