Artículos de revistas sobre el tema "Kv7.2/3"
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Hernandez, Ciria C., Björn Falkenburger y Mark S. Shapiro. "Affinity for phosphatidylinositol 4,5-bisphosphate determines muscarinic agonist sensitivity of Kv7 K+ channels". Journal of General Physiology 134, n.º 5 (26 de octubre de 2009): 437–48. http://dx.doi.org/10.1085/jgp.200910313.
Texto completoMiceli, Francesco, Maria V. Soldovieri, Paolo Ambrosino, Laura Manocchio, Ilaria Mosca y Maurizio Taglialatela. "Pharmacological Targeting of Neuronal Kv7.2/3 Channels: A Focus on Chemotypes and Receptor Sites". Current Medicinal Chemistry 25, n.º 23 (4 de julio de 2018): 2637–60. http://dx.doi.org/10.2174/0929867324666171012122852.
Texto completoPeretz, Asher, Anton Sheinin, Cuiyong Yue, Nurit Degani-Katzav, Gilad Gibor, Rachel Nachman, Anna Gopin et al. "Pre- and Postsynaptic Activation of M-Channels By a Novel Opener Dampens Neuronal Firing and Transmitter Release". Journal of Neurophysiology 97, n.º 1 (enero de 2007): 283–95. http://dx.doi.org/10.1152/jn.00634.2006.
Texto completoWright, Andrew B., Khrystyna Yu Sukhanova y Keith S. Elmslie. "KV7 channels are potential regulators of the exercise pressor reflex". Journal of Neurophysiology 126, n.º 1 (1 de julio de 2021): 1–10. http://dx.doi.org/10.1152/jn.00700.2020.
Texto completoBarro-Soria, Rene. "Effects of small molecules on neurodevelopmental disorder-associated Kv7.2/3 mutations". Biophysical Journal 123, n.º 3 (febrero de 2024): 528a. http://dx.doi.org/10.1016/j.bpj.2023.11.3192.
Texto completoPeretz, Asher S., Eti Patrich, Polina Kornilov, Nataly Menaker y Bernard Attali. "A Novel Compound Targeting Kv7.2/3 Channels Relieves Inflammatory and Neuropathic Pain". Biophysical Journal 106, n.º 2 (enero de 2014): 141a. http://dx.doi.org/10.1016/j.bpj.2013.11.820.
Texto completoLiu, Wenjing y Jérôme J. Devaux. "Calmodulin orchestrates the heteromeric assembly and the trafficking of KCNQ2/3 (Kv7.2/3) channels in neurons". Molecular and Cellular Neuroscience 58 (enero de 2014): 40–52. http://dx.doi.org/10.1016/j.mcn.2013.12.005.
Texto completoSurur, Abdrrahman S., Christian Bock, Kristin Beirow, Konrad Wurm, Lukas Schulig, Markus K. Kindermann, Werner Siegmund, Patrick J. Bednarski y Andreas Link. "Flupirtine and retigabine as templates for ligand-based drug design of KV7.2/3 activators". Organic & Biomolecular Chemistry 17, n.º 18 (2019): 4512–22. http://dx.doi.org/10.1039/c9ob00511k.
Texto completoLi, S., V. Choi y T. Tzounopoulos. "Pathogenic plasticity of Kv7.2/3 channel activity is essential for the induction of tinnitus". Proceedings of the National Academy of Sciences 110, n.º 24 (28 de mayo de 2013): 9980–85. http://dx.doi.org/10.1073/pnas.1302770110.
Texto completoMiranda, Pablo, Alba Cadaveira-Mosquera, Rafaela Gonzalez-Montelongo, Alvaro Villarroel, Jose Antonio Lamas, Diego Alvarez de la Rosa y Teresa Giraldez. "Regulation of the Kv7.2/3 Channels by the Neuronal Serum-and Gluococorticoids-Regulated Kinase 1.1". Biophysical Journal 104, n.º 2 (enero de 2013): 268a. http://dx.doi.org/10.1016/j.bpj.2012.11.1505.
Texto completoSander, Svenja E., Catherine Lambrecht y Angelika Richter. "The KV7.2/3 preferring channel opener ICA 27243 attenuates L-DOPA-induced dyskinesia in hemiparkinsonian rats". Neuroscience Letters 545 (junio de 2013): 59–63. http://dx.doi.org/10.1016/j.neulet.2013.04.017.
Texto completoPablo, Juan Lorenzo y Geoffrey S. Pitt. "FGF14 is a regulator of KCNQ2/3 channels". Proceedings of the National Academy of Sciences 114, n.º 1 (19 de diciembre de 2016): 154–59. http://dx.doi.org/10.1073/pnas.1610158114.
Texto completoLee, Inn-Chi, Jiann-Jou Yang, Ying-Ming Liou y Swee-Hee Wong. "KCNQ2 Selectivity Filter Mutations Cause Kv7.2 M-Current Dysfunction and Configuration Changes Manifesting as Epileptic Encephalopathies and Autistic Spectrum Disorders". Cells 11, n.º 5 (5 de marzo de 2022): 894. http://dx.doi.org/10.3390/cells11050894.
Texto completoRoeloffs, Rosemarie, Alan D. Wickenden, Christopher Crean, Stephen Werness, Grant McNaughton-Smith, James Stables, James O. McNamara, Neil Ghodadra y Greg C. Rigdon. "In Vivo Profile of ICA-27243 [N-(6-Chloro-pyridin-3-yl)-3,4-difluoro-benzamide], a Potent and Selective KCNQ2/Q3 (Kv7.2/Kv7.3) Activator in Rodent Anticonvulsant Models". Journal of Pharmacology and Experimental Therapeutics 326, n.º 3 (24 de junio de 2008): 818–28. http://dx.doi.org/10.1124/jpet.108.137794.
Texto completoEl-Chemali, Léa El, Suzan Boutary, Song Liu, Guo-Jun Liu, Ryan J. Middleton, Richard B. Banati, Gregor Bahrenberg, Rainer Rupprecht, Michael Schumacher y Liliane Massaad-Massade. "GRT-X Stimulates Dorsal Root Ganglia Axonal Growth in Culture via TSPO and Kv7.2/3 Potassium Channel Activation". International Journal of Molecular Sciences 25, n.º 13 (3 de julio de 2024): 7327. http://dx.doi.org/10.3390/ijms25137327.
Texto completoSedivy, Vojtech, Shreena Joshi, Youssef Ghaly, Roman Mizera, Marie Zaloudikova, Sean Brennan, Jana Novotna, Jan Herget y Alison M. Gurney. "Role of Kv7 channels in responses of the pulmonary circulation to hypoxia". American Journal of Physiology-Lung Cellular and Molecular Physiology 308, n.º 1 (1 de enero de 2015): L48—L57. http://dx.doi.org/10.1152/ajplung.00362.2013.
Texto completoWu, Yong-Jin, Charles M. Conway, Li-Qiang Sun, Frederic Machet, Jie Chen, Ping Chen, Huan He et al. "Discovery of (S,E)-3-(2-fluorophenyl)-N-(1-(3-(pyridin-3-yloxy)phenyl)ethyl)-acrylamide as a potent and efficacious KCNQ2 (Kv7.2) opener for the treatment of neuropathic pain". Bioorganic & Medicinal Chemistry Letters 23, n.º 22 (noviembre de 2013): 6188–91. http://dx.doi.org/10.1016/j.bmcl.2013.08.092.
Texto completoDickson, Eamonn J., Björn H. Falkenburger y Bertil Hille. "Quantitative properties and receptor reserve of the IP3 and calcium branch of Gq-coupled receptor signaling". Journal of General Physiology 141, n.º 5 (29 de abril de 2013): 521–35. http://dx.doi.org/10.1085/jgp.201210886.
Texto completoFalkenburger, Björn H., Eamonn J. Dickson y Bertil Hille. "Quantitative properties and receptor reserve of the DAG and PKC branch of Gq-coupled receptor signaling". Journal of General Physiology 141, n.º 5 (29 de abril de 2013): 537–55. http://dx.doi.org/10.1085/jgp.201210887.
Texto completoAnta, Begoña, Carlos Martín-Rodríguez, Carolina Gomis-Perez, Laura Calvo, Saray López-Benito, Andrés A. Calderón-García, Cristina Vicente-García, Álvaro Villarroel y Juan C. Arévalo. "Ubiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3)". Journal of Biological Chemistry 291, n.º 36 (21 de julio de 2016): 19132–45. http://dx.doi.org/10.1074/jbc.m116.722637.
Texto completoErdem, Fatma A. "Phosphorylation of KV7.2 regulates its PIP2 sensitivity". Intrinsic Activity 3, Suppl. 2 (9 de septiembre de 2015): A2.21. http://dx.doi.org/10.25006/ia.3.s2-a2.21.
Texto completoAndersen, Martin N., Søren-Peter Olesen y Hanne B. Rasmussen. "Kv7.1 surface expression is regulated by epithelial cell polarization". American Journal of Physiology-Cell Physiology 300, n.º 4 (abril de 2011): C814—C824. http://dx.doi.org/10.1152/ajpcell.00390.2010.
Texto completoTelezhkin, Vsevolod, Alison M. Thomas, Stephen C. Harmer, Andrew Tinker y David A. Brown. "A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)P2". Pflügers Archiv - European Journal of Physiology 465, n.º 7 (6 de enero de 2013): 945–53. http://dx.doi.org/10.1007/s00424-012-1199-3.
Texto completoAndersen, Martin Nybo, Katarzyna Krzystanek, Frederic Petersen, Sofia Hammami Bomholtz, Søren-Peter Olesen, Hugues Abriel, Thomas Jespersen y Hanne Borger Rasmussen. "A Phosphoinositide 3-Kinase (PI3K)-serum- and glucocorticoid-inducible Kinase 1 (SGK1) Pathway Promotes Kv7.1 Channel Surface Expression by Inhibiting Nedd4-2 Protein". Journal of Biological Chemistry 288, n.º 52 (8 de noviembre de 2013): 36841–54. http://dx.doi.org/10.1074/jbc.m113.525931.
Texto completoDai, Shuiping, Duane D. Hall y Johannes W. Hell. "Supramolecular Assemblies and Localized Regulation of Voltage-Gated Ion Channels". Physiological Reviews 89, n.º 2 (abril de 2009): 411–52. http://dx.doi.org/10.1152/physrev.00029.2007.
Texto completoAmin, Ahmad S., John R. Giudicessi, Anke J. Tijsen, Anne M. Spanjaart, Yolan J. Reckman, Christine A. Klemens, Michael W. Tanck et al. "Variants in the 3′ untranslated region of the KCNQ1-encoded Kv7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an allele-specific manner". European Heart Journal 33, n.º 6 (23 de diciembre de 2011): 714–23. http://dx.doi.org/10.1093/eurheartj/ehr473.
Texto completoGiudicessi, J. R., A. S. Amin, A. J. Tjisen, C. A. Klemens, J. D. Kapplinger, N. Hofman, Y. Pinto, A. A. Wilde y M. J. Ackerman. "Modification of Disease Severity by Functional Variants in the 3′ Untranslated Region of the KCNQ1-Encoded Kv7.1 Channel is Most Pronounced in Patients Harboring Dominant-Negative LQT1-Causative Mutations". Heart Rhythm 8, n.º 11 (noviembre de 2011): 1827. http://dx.doi.org/10.1016/j.hrthm.2011.09.050.
Texto completoHaick, Jennifer M., Lioubov I. Brueggemann, Leanne L. Cribbs, Mitchell F. Denning, Jeffrey Schwartz y Kenneth L. Byron. "PKC-dependent regulation of Kv7.5 channels by the bronchoconstrictor histamine in human airway smooth muscle cells". American Journal of Physiology-Lung Cellular and Molecular Physiology 312, n.º 6 (1 de junio de 2017): L822—L834. http://dx.doi.org/10.1152/ajplung.00567.2016.
Texto completoSheng, Zhao-Fu, Hua Zhang, PeiRu Zheng, Shanyan Chen, Zezong Gu, Jing-Jing Zhou, Jeffery G. Phaup et al. "Impaired Kv7 channel activity in the central amygdala contributes to elevated sympathetic outflow in hypertension". Cardiovascular Research, 14 de febrero de 2021. http://dx.doi.org/10.1093/cvr/cvab031.
Texto completoCelentano, Camilla, Lidia Carotenuto, Francesco Miceli, Giusy Carleo, Brunella Corrado, Giulia Baroli, Stefania Iervolino, Raffaele Vecchione, Maurizio Taglialatela y Vincenzo Barrese. "Kv7 CHANNELS ACTIVATION REDUCES BRAIN ENDOTHELIAL CELLS PERMEABILITY AND PREVENTS KAINIC ACID INDUCED BLOOD BRAIN BARRIER DAMAGE". American Journal of Physiology-Cell Physiology, 29 de enero de 2024. http://dx.doi.org/10.1152/ajpcell.00709.2023.
Texto completoVarghese, Nissi, Bruno Moscoso, Ana Chavez, Kristen Springer, Erika Ortiz, Heun Soh, Sabato Santaniello, Atul Maheshwari y Anastasios V. Tzingounis. "KCNQ2/3 Gain-of-Function Variants and Cell Excitability: Differential Effects in CA1 vs. L2/3 pyramidal neurons". Journal of Neuroscience, 22 de agosto de 2023, JN—RM—0980–23. http://dx.doi.org/10.1523/jneurosci.0980-23.2023.
Texto completoLi, Shuang, Bopanna I. Kalappa y Thanos Tzounopoulos. "Noise-induced plasticity of KCNQ2/3 and HCN channels underlies vulnerability and resilience to tinnitus". eLife 4 (27 de agosto de 2015). http://dx.doi.org/10.7554/elife.07242.
Texto completoPerez-Vizcaino, Francisco, Angel Cogolludo y Gema Mondejar-Parreño. "Transcriptomic profile of cationic channels in human pulmonary arterial hypertension". Scientific Reports 11, n.º 1 (4 de agosto de 2021). http://dx.doi.org/10.1038/s41598-021-95196-z.
Texto completoTracy, Gregory C., Angelina R. Wilton, Justin S. Rhodes y Hee Jung Chung. "Heterozygous Deletion of Epilepsy Gene KCNQ2 Has Negligible Effects on Learning and Memory". Frontiers in Behavioral Neuroscience 16 (19 de julio de 2022). http://dx.doi.org/10.3389/fnbeh.2022.930216.
Texto completoLi, De-Pei, Zhao-Fu Sheng, Hua Zhang y Peiru Zheng. "Dysfunction of M channels in the insular cortex is involved in pathogenesis of primary hypertension". Physiology 39, S1 (mayo de 2024). http://dx.doi.org/10.1152/physiol.2024.39.s1.1993.
Texto completoFrench, Jacqueline A., Roger J. Porter, Emilio Perucca, Martin J. Brodie, Michael A. Rogawski, Simon Pimstone, Ernesto Aycardi et al. "Efficacy and Safety of XEN1101, a Novel Potassium Channel Opener, in Adults With Focal Epilepsy". JAMA Neurology, 9 de octubre de 2023. http://dx.doi.org/10.1001/jamaneurol.2023.3542.
Texto completoPant, Shashank, Jiaren Zhang, Eung Chang Kim, Kin Lam, Hee Jung Chung y Emad Tajkhorshid. "PIP2-dependent coupling of voltage sensor and pore domains in Kv7.2 channel". Communications Biology 4, n.º 1 (14 de octubre de 2021). http://dx.doi.org/10.1038/s42003-021-02729-3.
Texto completoPant, Shashank, Jiaren Zhang, Eung Chang Kim, Kin Lam, Hee Jung Chung y Emad Tajkhorshid. "PIP2-dependent coupling of voltage sensor and pore domains in Kv7.2 channel". Communications Biology 4, n.º 1 (14 de octubre de 2021). http://dx.doi.org/10.1038/s42003-021-02729-3.
Texto completoKlemz, Alexander, Florian Wildner, Ecem Tütüncü y Zoltan Gerevich. "Regulation of Hippocampal Gamma Oscillations by Modulation of Intrinsic Neuronal Excitability". Frontiers in Neural Circuits 15 (26 de enero de 2022). http://dx.doi.org/10.3389/fncir.2021.778022.
Texto completoYang, Gui-mei, Fu-yun Tian, Yan-wen Shen, Chuan-yan Yang, Hui Yuan, Ping Li y Zhao-bing Gao. "Functional characterization and in vitro pharmacological rescue of KCNQ2 pore mutations associated with epileptic encephalopathy". Acta Pharmacologica Sinica, 17 de marzo de 2023. http://dx.doi.org/10.1038/s41401-023-01073-y.
Texto completoJULIANA, CHRISTINE y DIVA DE LEON. "1745-P: Voltage-Gated K+ Channel Kv7.1 Is an Important Regulator of Insulin Secretion in Normal and Hyperinsulinemic Islets". Diabetes 72, Supplement_1 (20 de junio de 2023). http://dx.doi.org/10.2337/db23-1745-p.
Texto completoTrancuccio, A., A. Mazzanti, D. Kukavica, M. Marino, N. Monteforte, R. Bloise, L. Braghieri et al. "Mutation site-specific risk profile in patients with Type 1 Long QT Syndrome". European Heart Journal 41, Supplement_2 (1 de noviembre de 2020). http://dx.doi.org/10.1093/ehjci/ehaa946.0743.
Texto completoLiao, Qian-Qian, Qing-Qing Dong, Hui Zhang, Hua-Pan Shu, Yu-Chi Tu y Li-Jun Yao. "Contributions of SGK3 to transporter-related diseases". Frontiers in Cell and Developmental Biology 10 (1 de diciembre de 2022). http://dx.doi.org/10.3389/fcell.2022.1007924.
Texto completoSvecova, O., R. Kula, L. Chmelikova, J. Hosek, I. Synkova, T. Novotny y M. Bebarova. "Clinical, genetic and functional analysis of R562S-Kv7.1 mutation associated with long QT syndrome type 1". EP Europace 23, Supplement_3 (1 de mayo de 2021). http://dx.doi.org/10.1093/europace/euab116.560.
Texto completoBomholtz, S. H., R. Simo-Vicens, L. Abildgaard, N. G. Edvardsson, U. S. Soerensen, M. Grunnet, J. G. Diness y B. H. Bentzen. "P699Mechanisms of action of the small conductance Ca2+-activated K+-channel modulator AP30663, a novel compound being developed for treatment of atrial fibrillation in man". European Heart Journal 40, Supplement_1 (1 de octubre de 2019). http://dx.doi.org/10.1093/eurheartj/ehz747.0304.
Texto completoKato, Koichi, Holly M. Isbell, Véronique Fressart, Isabelle Denjoy, Amal Debbiche, Hideki Itoh, Jacques Poinsot et al. "Novel CALM3 Variant Causing Calmodulinopathy With Variable Expressivity in a 4-Generation Family". Circulation: Arrhythmia and Electrophysiology 15, n.º 3 (marzo de 2022). http://dx.doi.org/10.1161/circep.121.010572.
Texto completoGiammarino, L., S. Nimani, S. Bains, N. Alerni, D. J. Tester, N. Christoforou, J. Louradour et al. "In vivo KCNQ1-suppression-replacement gene therapy in transgenic rabbits with type 1 long QT syndrome". Europace 25, Supplement_1 (24 de mayo de 2023). http://dx.doi.org/10.1093/europace/euad122.594.
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