Artículos de revistas sobre el tema "Isogenic cellular models"
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Paredes-Redondo, A. y Y. Y. Lin. "Developing novel human isogenic cellular models for Duchenne muscular dystrophy". Neuromuscular Disorders 27 (marzo de 2017): S6. http://dx.doi.org/10.1016/s0960-8966(17)30234-1.
Texto completoZhang, Yuting, Emily Wilt y Xin Lu. "Human Isogenic Cell Line Models for Neutrophils and Myeloid-Derived Suppressor Cells". International Journal of Molecular Sciences 21, n.º 20 (18 de octubre de 2020): 7709. http://dx.doi.org/10.3390/ijms21207709.
Texto completoBenarroch, Louise, Julia Madsen-Østerbye, Mohamed Abdelhalim, Kamel Mamchaoui, Jessica Ohana, Anne Bigot, Vincent Mouly, Gisèle Bonne, Anne T. Bertrand y Philippe Collas. "Cellular and Genomic Features of Muscle Differentiation from Isogenic Fibroblasts and Myoblasts". Cells 12, n.º 15 (3 de agosto de 2023): 1995. http://dx.doi.org/10.3390/cells12151995.
Texto completoPavan, Eleonora, Maximiliano Ormazabal, Paolo Peruzzo, Emilio Vaena, Paula Rozenfeld y Andrea Dardis. "CRISPR/Cas9 Editing for Gaucher Disease Modelling". International Journal of Molecular Sciences 21, n.º 9 (5 de mayo de 2020): 3268. http://dx.doi.org/10.3390/ijms21093268.
Texto completoKarwacka, Marianna y Marta Olejniczak. "Advances in Modeling Polyglutamine Diseases Using Genome Editing Tools". Cells 11, n.º 3 (2 de febrero de 2022): 517. http://dx.doi.org/10.3390/cells11030517.
Texto completoKlementieva, Natalia, Daria Goliusova, Julia Krupinova, Vladislav Yanvarev, Alexandra Panova, Natalia Mokrysheva y Sergey L. Kiselev. "A Novel Isogenic Human Cell-Based System for MEN1 Syndrome Generated by CRISPR/Cas9 Genome Editing". International Journal of Molecular Sciences 22, n.º 21 (8 de noviembre de 2021): 12054. http://dx.doi.org/10.3390/ijms222112054.
Texto completoBoussaad, Ibrahim, Emily K. Dolezal, Fabiana Perna, Stephen D. Nimer y Eirini P. Papapetrou. "IPS Cells From Del(7q)-MDS Patients Display Impaired Proliferation and Hematopoietic Commitment". Blood 120, n.º 21 (16 de noviembre de 2012): 174. http://dx.doi.org/10.1182/blood.v120.21.174.174.
Texto completoMuto, Valentina, Federica Benigni, Valentina Magliocca, Rossella Borghi, Elisabetta Flex, Valentina Pallottini, Alessandro Rosa, Claudia Compagnucci y Marco Tartaglia. "CRISPR/Cas9 and piggyBac Transposon-Based Conversion of a Pathogenic Biallelic TBCD Variant in a Patient-Derived iPSC Line Allows Correction of PEBAT-Related Endophenotypes". International Journal of Molecular Sciences 24, n.º 9 (28 de abril de 2023): 7988. http://dx.doi.org/10.3390/ijms24097988.
Texto completoLi, Fenfang, Igor Cima, Jess Honganh Vo, Min-Han Tan y Claus Dieter Ohl. "Single Cell Hydrodynamic Stretching and Microsieve Filtration Reveal Genetic, Phenotypic and Treatment-Related Links to Cellular Deformability". Micromachines 11, n.º 5 (9 de mayo de 2020): 486. http://dx.doi.org/10.3390/mi11050486.
Texto completoPatel, Ronak, Shyanne Page y Abraham Jacob Al-Ahmad. "Isogenic blood-brain barrier models based on patient-derived stem cells display inter-individual differences in cell maturation and functionality". Journal of Neurochemistry 142, n.º 1 (14 de mayo de 2017): 74–88. http://dx.doi.org/10.1111/jnc.14040.
Texto completoBoussaad, Ibrahim, Andriana Kotini, Emily K. Dolezal, Stephen Nimer y Eirini P. Papapetrou. "An iPSC-Based Model Of MDS For Phenotype-Driven Gene and Drug Discovery". Blood 122, n.º 21 (15 de noviembre de 2013): 859. http://dx.doi.org/10.1182/blood.v122.21.859.859.
Texto completoHaley, John A., Christian F. Ruiz, Emily D. Montal, Daifeng Wang, John D. Haley y Geoffrey D. Girnun. "Decoupling of Nrf2 Expression Promotes Mesenchymal State Maintenance in Non-Small Cell Lung Cancer". Cancers 11, n.º 10 (2 de octubre de 2019): 1488. http://dx.doi.org/10.3390/cancers11101488.
Texto completoGhosal, Abhisek, Stefan Jellbauer, Rubina Kapadia, Manuela Raffatellu y Hamid M. Said. "Salmonellainfection inhibits intestinal biotin transport: cellular and molecular mechanisms". American Journal of Physiology-Gastrointestinal and Liver Physiology 309, n.º 2 (15 de julio de 2015): G123—G131. http://dx.doi.org/10.1152/ajpgi.00112.2015.
Texto completoCeballos-Garzon, Andres, Elvira Roman, Jesús Pla, Fabrice Pagniez, Daniela Amado, Carlos J. Alméciga-Díaz, Patrice Le Pape y Claudia M. Parra-Giraldo. "CRISPR-Cas9 approach confirms Calcineurin-responsive zinc finger 1 (Crz1) transcription factor as a promising therapeutic target in echinocandin-resistant Candida glabrata". PLOS ONE 17, n.º 3 (18 de marzo de 2022): e0265777. http://dx.doi.org/10.1371/journal.pone.0265777.
Texto completoKálmán, Sára, Edit Hathy y János M. Réthelyi. "A Dishful of a Troubled Mind: Induced Pluripotent Stem Cells in Psychiatric Research". Stem Cells International 2016 (2016): 1–21. http://dx.doi.org/10.1155/2016/7909176.
Texto completoWang, Wei, Tiansu Wang, Andriana G. Kotini, Camelia Iancu-Rubin, Ronald Hoffman y Eirini P. Papapetrou. "Modeling Calreticulin-Mutant Myeloproliferative Neoplasms with Isogenic Induced Pluripotent Stem Cells". Blood 132, Supplement 1 (29 de noviembre de 2018): 4319. http://dx.doi.org/10.1182/blood-2018-99-111512.
Texto completoХамидуллина, А. И., Э. Р. Гандалипов, Я. Е. Абраменко, К. В. Чернов, Т. А. Кирюхина, А. В. Брутер y В. В. Татарский. "Creation of A549 and MCF7 tumor sublines with knockout of TP53 using CRISPR/Cas9". Nauchno-prakticheskii zhurnal «Medicinskaia genetika 22, n.º 11 (19 de diciembre de 2023): 27–34. http://dx.doi.org/10.25557/2073-7998.2023.11.27-34.
Texto completoCharlebois, Daniel A., Kevin Hauser, Sylvia Marshall y Gábor Balázsi. "Multiscale effects of heating and cooling on genes and gene networks". Proceedings of the National Academy of Sciences 115, n.º 45 (19 de octubre de 2018): E10797—E10806. http://dx.doi.org/10.1073/pnas.1810858115.
Texto completoLee, Hans C., Hua Wang, Bing-Zong Li, Zhiqiang Wang, Richard Julian Jones, Dongmin Gu, Sean O'Brien, Richard E. Davis y Robert Z. Orlowski. "CX-5461, a Novel RNA Polymerase I Inhibitor, Is Active Against Wild-Type and Mutant p53 Myeloma Models". Blood 122, n.º 21 (15 de noviembre de 2013): 4438. http://dx.doi.org/10.1182/blood.v122.21.4438.4438.
Texto completovan Waardenburg, Robert C. A. M., Laurina A. de Jong, Foke van Delft, Maria A. J. van Eijndhoven, Melanie Bohlander, Mary-Ann Bjornsti, Jaap Brouwer y Jan H. M. Schellens. "Homologous recombination is a highly conserved determinant of the synergistic cytotoxicity between cisplatin and DNA topoisomerase I poisons". Molecular Cancer Therapeutics 3, n.º 4 (1 de abril de 2004): 393–402. http://dx.doi.org/10.1158/1535-7163.393.3.4.
Texto completoRakotomalala, Andria, Paul Lewandowski, Quentin Bailleul, Clara Savary, Mélanie Arcicasa, Christine Bal, Maud Hamadou et al. "Abstract 1671: Engineering new cellular models to decipher H3.3K27M mutation role in DIPGs' resistance to therapies". Cancer Research 82, n.º 12_Supplement (15 de junio de 2022): 1671. http://dx.doi.org/10.1158/1538-7445.am2022-1671.
Texto completoDe Souza, Cristabelle, Jill A. Madden, Dennis Minn, Vigneshwari Easwar Kumar, Dennis J. Montoya, Roshni Nambiar, Zheng Zhu et al. "The P72R Polymorphism in R248Q/W p53 Mutants Modifies the Mutant Effect on Epithelial to Mesenchymal Transition Phenotype and Cell Invasion via CXCL1 Expression". International Journal of Molecular Sciences 21, n.º 21 (28 de octubre de 2020): 8025. http://dx.doi.org/10.3390/ijms21218025.
Texto completoJungles, Kassidy M., Andrea M. Pesch, Nicole Hirsh, Anna R. Michmerhuizen, Kari Wilder-Romans, Benjamin C. Chandler, Meilan Liu et al. "Abstract 216: Expression of DNA damage response proteins modifies the efficacy of CDK4/6 inhibitor-mediated radiosensitization in breast cancer models". Cancer Research 82, n.º 12_Supplement (15 de junio de 2022): 216. http://dx.doi.org/10.1158/1538-7445.am2022-216.
Texto completoChakrabarty, Anindita, Sreeraj Surendran, Neil E. Bhola, Vishnu S. Mishra, Tasaduq Hussain Wani, Khemraj S. Baghel, Carlos L. Arteaga, Rohini Garg y Goutam Chowdhury. "The H1047R PIK3CA oncogene induces a senescence-like state, pleiotropy and acute HSP90 dependency in HER2+ mammary epithelial cells". Carcinogenesis 40, n.º 10 (18 de junio de 2019): 1179–90. http://dx.doi.org/10.1093/carcin/bgz118.
Texto completoCostamagna, Gianluca, Giacomo Pietro Comi y Stefania Corti. "Advancing Drug Discovery for Neurological Disorders Using iPSC-Derived Neural Organoids". International Journal of Molecular Sciences 22, n.º 5 (6 de marzo de 2021): 2659. http://dx.doi.org/10.3390/ijms22052659.
Texto completoWenzl, Kerstin, Michelle Manske, Paola Martinez, Stephen Ansell, James R. Cerhan y Anne J. Novak. "Isogenic Loss of TNFAIP3 in Waldenstrom Macroglobulinemia Enhances MYD88L265P-Driven Signaling". Blood 128, n.º 22 (2 de diciembre de 2016): 4100. http://dx.doi.org/10.1182/blood.v128.22.4100.4100.
Texto completoFerri-Borgogno, Sammy, Sugata Barui, Amberly M. McGee, Tamara Griffiths, Pankaj K. Singh, Cortt G. Piett, Bidyut Ghosh et al. "Paradoxical Role of AT-rich Interactive Domain 1A in Restraining Pancreatic Carcinogenesis". Cancers 12, n.º 9 (21 de septiembre de 2020): 2695. http://dx.doi.org/10.3390/cancers12092695.
Texto completoHollywood, Jennifer A., Aneta Przepiorski, Randall F. D’Souza, Sreevalsan Sreebhavan, Ernst J. Wolvetang, Patrick T. Harrison, Alan J. Davidson y Teresa M. Holm. "Use of Human Induced Pluripotent Stem Cells and Kidney Organoids To Develop a Cysteamine/mTOR Inhibition Combination Therapy for Cystinosis". Journal of the American Society of Nephrology 31, n.º 5 (20 de marzo de 2020): 962–82. http://dx.doi.org/10.1681/asn.2019070712.
Texto completoJung, Moonjung, Stefan Cordes, Jizhong Zou, Shiqin J. Yu, Xavi Guitart, So Gun Hong, Vinh Dang et al. "GATA2 deficiency and human hematopoietic development modeled using induced pluripotent stem cells". Blood Advances 2, n.º 23 (11 de diciembre de 2018): 3553–65. http://dx.doi.org/10.1182/bloodadvances.2018017137.
Texto completoSidhu, Ishnoor, Sonali P. Barwe, Raju K. Pillai y Anilkumar Gopalakrishnapillai. "Harnessing the Power of Induced Pluripotent Stem Cells and Gene Editing Technology: Therapeutic Implications in Hematological Malignancies". Cells 10, n.º 10 (9 de octubre de 2021): 2698. http://dx.doi.org/10.3390/cells10102698.
Texto completoMalladi, Srinivas. "Abstract P1-06-08: Metabolic diversity determines metastatic fitness of breast cancer brain-tropic cells". Cancer Research 82, n.º 4_Supplement (15 de febrero de 2022): P1–06–08—P1–06–08. http://dx.doi.org/10.1158/1538-7445.sabcs21-p1-06-08.
Texto completoGrantcharova, Nina, Verena Peters, Claudia Monteiro, Katherina Zakikhany y Ute Römling. "Bistable Expression of CsgD in Biofilm Development of Salmonella enterica Serovar Typhimurium". Journal of Bacteriology 192, n.º 2 (6 de noviembre de 2009): 456–66. http://dx.doi.org/10.1128/jb.01826-08.
Texto completoGerritsen, Jacqueline S., Joseph S. Faraguna, Rudy Bonavia, Frank B. Furnari y Forest M. White. "Predictive data-driven modeling of C-terminal tyrosine function in the EGFR signaling network". Life Science Alliance 6, n.º 8 (11 de mayo de 2023): e202201466. http://dx.doi.org/10.26508/lsa.202201466.
Texto completoKotini, Andriana, Jeffrey J. Delrow, Timothy A. Graubert, Stephen Nimer y Eirini P. Papapetrou. "Functional Dissection of Chromosome 7q Loss and Haploinsufficient Gene Discovery Using iPSC Models of MDS". Blood 124, n.º 21 (6 de diciembre de 2014): 524. http://dx.doi.org/10.1182/blood.v124.21.524.524.
Texto completoLemaire, Sandrine, Klaudia Kosowska-Shick, Peter C. Appelbaum, Gunther Verween, Paul M. Tulkens y Françoise Van Bambeke. "Cellular Pharmacodynamics of the Novel Biaryloxazolidinone Radezolid: Studies with Infected Phagocytic and Nonphagocytic cells, Using Staphylococcus aureus, Staphylococcus epidermidis, Listeria monocytogenes, and Legionella pneumophila". Antimicrobial Agents and Chemotherapy 54, n.º 6 (12 de abril de 2010): 2549–59. http://dx.doi.org/10.1128/aac.01724-09.
Texto completoJavier, Rodrigo y Craig Horbinski. "TAMI-48. THE KETOGENIC DIET IS INEFFECTIVE IN PRECLINICAL MODELS OF IDH1 WILD-TYPE AND IDH1 MUTANT GLIOMA". Neuro-Oncology 23, Supplement_6 (2 de noviembre de 2021): vi208. http://dx.doi.org/10.1093/neuonc/noab196.831.
Texto completoFrank, Karen M., Tong Zhou, Liliana Moreno-Vinasco, Brian Hollett, Joe G. N. Garcia y Juliane Bubeck Wardenburg. "Host Response Signature to Staphylococcus aureus Alpha-Hemolysin Implicates Pulmonary Th17 Response". Infection and Immunity 80, n.º 9 (25 de junio de 2012): 3161–69. http://dx.doi.org/10.1128/iai.00191-12.
Texto completoLara-Chacón, Bárbara, Sandra L. Guerrero-Rodríguez, Karla J. Ramírez-Hernández, Angélica Yamilett Robledo-Rivera, Marco Antonio Velasco Velazquez, Roberto Sánchez-Olea y Mónica Raquel Calera. "Gpn3 Is Essential for Cell Proliferation of Breast Cancer Cells Independent of Their Malignancy Degree". Technology in Cancer Research & Treatment 18 (1 de enero de 2019): 153303381987082. http://dx.doi.org/10.1177/1533033819870823.
Texto completoMy, Ilaria y Elisa Di Pasquale. "Genetic Cardiomyopathies: The Lesson Learned from hiPSCs". Journal of Clinical Medicine 10, n.º 5 (9 de marzo de 2021): 1149. http://dx.doi.org/10.3390/jcm10051149.
Texto completoManceau, Line, Julien Richard Albert, Pier-Luigi Lollini, Maxim V. C. Greenberg, Pascale Gilardi-Hebenstreit y Vanessa Ribes. "Divergent transcriptional and transforming properties of PAX3-FOXO1 and PAX7-FOXO1 paralogs". PLOS Genetics 18, n.º 5 (23 de mayo de 2022): e1009782. http://dx.doi.org/10.1371/journal.pgen.1009782.
Texto completoKargaran, Parisa K., Jared M. Evans, Sara E. Bodbin, James G. W. Smith, Timothy J. Nelson, Chris Denning y Diogo Mosqueira. "Mitochondrial DNA: Hotspot for Potential Gene Modifiers Regulating Hypertrophic Cardiomyopathy". Journal of Clinical Medicine 9, n.º 8 (23 de julio de 2020): 2349. http://dx.doi.org/10.3390/jcm9082349.
Texto completoNtai, Ioanna, Luca Fornelli, Caroline J. DeHart, Josiah E. Hutton, Peter F. Doubleday, Richard D. LeDuc, Alexandra J. van Nispen et al. "Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk". Proceedings of the National Academy of Sciences 115, n.º 16 (2 de abril de 2018): 4140–45. http://dx.doi.org/10.1073/pnas.1716122115.
Texto completoJacobs, Keith M., Sandeep Misri, Barbara Meyer, Suyash Raj, Cheri L. Zobel, Barry P. Sleckman, Dennis E. Hallahan y Girdhar G. Sharma. "Unique epigenetic influence of H2AX phosphorylation and H3K56 acetylation on normal stem cell radioresponses". Molecular Biology of the Cell 27, n.º 8 (15 de abril de 2016): 1332–45. http://dx.doi.org/10.1091/mbc.e16-01-0017.
Texto completoRosenthal, Dean S., Elijah Finn, Devin Teehan, Nusrat Islam, Veerupaxagouda Patil, Bonnie Carney, Scott S. Rosenthal, Lucia Dussan, Cynthia M. Simbulan-Rosenthal y Peter Sykora. "Abstract B035: Developing the UValidate platform to measure DNA damage and repair capacity in isogenic donor-derived skin keratinocytes, fibroblasts and melanocyte cell-lines with different Fitzpatrick phototypes". Cancer Research 84, n.º 1_Supplement (9 de enero de 2024): B035. http://dx.doi.org/10.1158/1538-7445.dnarepair24-b035.
Texto completoVötsch, Désirée, Maren Willenborg, Walter M. R. Oelemann, Graham Brogden y Peter Valentin-Weigand. "Membrane Binding, Cellular Cholesterol Content and Resealing Capacity Contribute to Epithelial Cell Damage Induced by Suilysin of Streptococcus suis". Pathogens 9, n.º 1 (30 de diciembre de 2019): 33. http://dx.doi.org/10.3390/pathogens9010033.
Texto completoMeng, Qingyuan, Xiao Ding, Xiaosong Liu, Hailong Wang, Ling Wang, Junwen Qiao, Hua Cao et al. "Abstract 503: ISM3412, a novel and selective MAT2A inhibitor for the treatment of cancer". Cancer Research 83, n.º 7_Supplement (4 de abril de 2023): 503. http://dx.doi.org/10.1158/1538-7445.am2023-503.
Texto completoJenkins, Samir V., Shruti Shah, Azemat Jamshidi-Parsian, Amir Mortazavi, Gunnar Boysen, Kieng B. Vang, Robert J. Griffin, Narasimhan Rajaram y Ruud P. Dings. "Abstract 1088: Acquired radiation resistance induces thiol-dependent cisplatin cross-resistance". Cancer Research 83, n.º 7_Supplement (4 de abril de 2023): 1088. http://dx.doi.org/10.1158/1538-7445.am2023-1088.
Texto completoTawil, Nadim, Rayhaan Bassawon, Brian Meehan, Laura Montermini, Dongsic Choi, Ali Nehme, Hamed Najafabadi et al. "OPTC-5. Molecular signatures of podoplanin expressing glioblastoma cell subsets with putative role in cancer associated thrombosis and microthrombosis". Neuro-Oncology Advances 3, Supplement_2 (1 de julio de 2021): ii7. http://dx.doi.org/10.1093/noajnl/vdab070.026.
Texto completoMaurissen, Thomas L., Masahide Kawatou, Víctor López-Dávila, Kenji Minatoya, Jun K. Yamashita y Knut Woltjen. "Modeling mutation-specific arrhythmogenic phenotypes in isogenic human iPSC-derived cardiac tissues". Scientific Reports 14, n.º 1 (31 de enero de 2024). http://dx.doi.org/10.1038/s41598-024-52871-1.
Texto completoLebedeva, Irina V., Michelle V. Wagner, Sunil Sahdeo, Yi-Fan Lu, Anuli Anyanwu-Ofili, Matthew B. Harms, Jehangir S. Wadia, Gunaretnam Rajagopal, Michael J. Boland y David B. Goldstein. "Precision genetic cellular models identify therapies protective against ER stress". Cell Death & Disease 12, n.º 8 (agosto de 2021). http://dx.doi.org/10.1038/s41419-021-04045-4.
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