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Literatura académica sobre el tema "Iron oxide microparticles"

Autor: Grafiati

Publicado: 21 de diciembre de 2024

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Artículos de revistas sobre el tema "Iron oxide microparticles"

Bica, Ioan, Eugen Mircea Anitas, Hyoung Jin Choi y Paula Sfirloaga. "Microwave-assisted synthesis and characterization of iron oxide microfibers". Journal of Materials Chemistry C 8, n.º 18 (2020): 6159–67. http://dx.doi.org/10.1039/c9tc05687d.

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Carrelo, Henrique, André R. Escoval, Tânia Vieira, Mercedes Jiménez-Rosado, Jorge Carvalho Silva, Alberto Romero, Paula Isabel P. Soares y João Paulo Borges. "Injectable Thermoresponsive Microparticle/Hydrogel System with Superparamagnetic Nanoparticles for Drug Release and Magnetic Hyperthermia Applications". Gels 9, n.º 12 (15 de diciembre de 2023): 982. http://dx.doi.org/10.3390/gels9120982.

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Cancer is a disease that continues to greatly impact our society. Developing new and more personalized treatment options is crucial to decreasing the cancer burden. In this study, we combined magnetic polysaccharide microparticles with a Pluronic thermoresponsive hydrogel to develop a multifunctional, injectable drug delivery system (DDS) for magnetic hyperthermia applications. Gellan gum and alginate microparticles were loaded with superparamagnetic iron oxide nanoparticles (SPIONs) with and without coating. The magnetic microparticles’ registered temperature increases up to 4 °C upon the application of an alternating magnetic field. These magnetic microparticles were mixed with drug-loaded microparticles, and, subsequently, this mixture was embedded within a Pluronic thermoresponsive hydrogel that is capable of being in the gel state at 37 °C. The proposed DDS was capable of slowly releasing methylene blue, used as a model drug, for up to 9 days. The developed hydrogel/microparticle system had a smaller rate of drug release compared with microparticles alone. This system proved to be a potential thermoresponsive DDS suitable for magnetic hyperthermia applications, thus enabling a synergistic treatment for cancer.

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Krajewski, M., K. Brzozka, W. S. Lin, H. M. Lin, M. Tokarczyk, J. Borysiuk, G. Kowalski y D. Wasik. "High temperature oxidation of iron–iron oxide core–shell nanowires composed of iron nanoparticles". Physical Chemistry Chemical Physics 18, n.º 5 (2016): 3900–3909. http://dx.doi.org/10.1039/c5cp07569f.

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Koudelkova, Zuzana, Zuzana Bytesnikova, Kledi Xhaxhiu, Monika Kremplova, David Hynek, Vojtech Adam y Lukas Richtera. "Electrochemical Evaluation of Selenium (IV) Removal from Its Aqueous Solutions by Unmodified and Modified Graphene Oxide". Molecules 24, n.º 6 (18 de marzo de 2019): 1063. http://dx.doi.org/10.3390/molecules24061063.

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The removal of selenium from superficial and waste water is a worldwide problem. The maximum limit according to the World Health Organization (WHO) for the selenium in the water is set at a concentration of 10 μg/L. Carbon based adsorbents have attracted much attention and recently demonstrated promising performance in removal of selenium. In this work, several materials (iron oxide based microparticles and graphene oxides materials) and their composites were prepared to remove Se(IV) from water. The graphene oxides were prepared according to the simplified Hummer’s method. In addition, the effect of pH, contact time and initial Se(IV) concentration was tested. An electrochemical method such as the differential pulse cathodic stripping voltammetry was used to determine the residual selenium concentration. From the experimental data, Langmuir adsorption model was used to calculate the maximum adsorption capacity. Graphene oxide particles modified by iron oxide based microparticles was the most promising material for the removal of Se(IV) from its aqueous solution at pH 2.0. Its adsorption efficiency reached more than 90% for a solution with given Se(IV) concentration, meanwhile its maximal recorded adsorption capacity was 18.69 mg/g.

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Žaimis, Uldis, Jūratė Jolanta Petronienė, Andrius Dzedzickis y Vytautas Bučinskas. "Stretch Sensor: Development of Biodegradable Film". Sensors 24, n.º 2 (21 de enero de 2024): 683. http://dx.doi.org/10.3390/s24020683.

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This article presents research on biodegradable stretch sensors produced using biological material. This sensor uses a piezoresistive effect to indicate stretch, which can be used for force measurement. In this work, an attempt was made to develop the composition of a sensitive material and to design a sensor. The biodegradable base was made from a κ-carrageenan compound mixed with Fe2O3 microparticles and glycerol. The influence of the weight fraction and iron oxide microparticles on the tensile strength and Young’s modulus was experimentally investigated. Tensile test specimens consisted of 10–25% iron oxide microparticles of various sizes. The results showed that increasing the mass fraction of the reinforcement improved the Young’s modulus compared to the pure sample and decreased the elongation percentage. The GF of the developed films varies from 0.67 to 10.47 depending on composition. In this paper, it was shown that the incorporation of appropriate amounts of Fe2O3 microparticles into κ-carrageenan can achieve dramatic improvements in mechanical properties, resulting in elongation of up to 10%. The developed sensors were experimentally tested, and their sensitivity, stability, and range were determined. Finally, conclusions were drawn on the results obtained.

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Kabiri, Shervin, Mahaveer D. Kurkuri, Tushar Kumeria y Dusan Losic. "Frit-free PDMS microfluidic device for chromatographic separation and on-chip detection". RSC Adv. 4, n.º 29 (2014): 15276–80. http://dx.doi.org/10.1039/c4ra01393j.

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A simple frit-free PDMS (polydimethylsiloxane) microfluidic chromatographic separation and detection device, packed with diatomaceous earth (DE) microparticles as a normal phase stationary material using iron oxide magnetic nanoparticles is described.

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Matsunaga, H., M. Kiguchi, B. Roth y P. D. Evans. "Visualisation of Metals in Pine Treated with Preservative Containing Copper and Iron Nanoparticles". IAWA Journal 29, n.º 4 (2008): 387–96. http://dx.doi.org/10.1163/22941932-90000193.

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In this study we compared the ability of conventional and field-emission scanning-electron-microscopy (FESEM) and energy-dispersive analysis of X-rays (EDX) to visualise and map inorganic nano and microparticles in Southern pine (Pinus sp.) treated with an aqueous dispersion of micronised copper-carbonate and iron oxide. Conventional SEM-EDX was able to detect areas of the wood microstructure that contained higher concentrations of copper and iron, but EDX maps were affected by drift and specimens suffered beam damage. The high brightness of the FESEM's electron beam at low accelerating voltages reduced beam damage and helped when mapping the distribution of copper and iron particles. The clarity of EDX maps was further improved by using drift-correction software and by mapping low energy X-rays. FESEM-EDX was able to resolve individual copper and iron microparticles. We conclude that FESEM-EDX shows promise as a means of resolving and mapping the distribution of inorganic metal particles in wood and that this may lead to greater use of the technology as interest in the treatment of wood with inorganic nano and microparticles grows.

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Tronc, E. y D. Bonnin. "Magnetic coupling among spinel iron oxide microparticles by Mössbauer spectroscopy". Journal de Physique Lettres 46, n.º 10 (1985): 437–43. http://dx.doi.org/10.1051/jphyslet:019850046010043700.

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Rodríguez, Cristian F., Paula Guzmán-Sastoque, Carolina Muñoz-Camargo, Luis H. Reyes, Johann F. Osma y Juan C. Cruz. "Enhancing Magnetic Micro- and Nanoparticle Separation with a Cost-Effective Microfluidic Device Fabricated by Laser Ablation of PMMA". Micromachines 15, n.º 8 (22 de agosto de 2024): 1057. http://dx.doi.org/10.3390/mi15081057.

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Superparamagnetic iron oxide micro- and nanoparticles have significant applications in biomedical and chemical engineering. This study presents the development and evaluation of a novel low-cost microfluidic device for the purification and hyperconcentration of these magnetic particles. The device, fabricated using laser ablation of polymethyl methacrylate (PMMA), leverages precise control over fluid dynamics to efficiently separate magnetic particles from non-magnetic ones. We assessed the device’s performance through Multiphysics simulations and empirical tests, focusing on the separation of magnetite nanoparticles from blue carbon dots and magnetite microparticles from polystyrene microparticles at various total flow rates (TFRs). For nanoparticle separation, the device achieved a recall of up to 93.3 ± 4% and a precision of 95.9 ± 1.2% at an optimal TFR of 2 mL/h, significantly outperforming previous models, which only achieved a 50% recall. Microparticle separation demonstrated an accuracy of 98.1 ± 1% at a TFR of 2 mL/h in both simulations and experimental conditions. The Lagrangian model effectively captured the dynamics of magnetite microparticle separation from polystyrene microparticles, with close agreement between simulated and experimental results. Our findings underscore the device’s robust capability in distinguishing between magnetic and non-magnetic particles at both micro- and nanoscales. This study highlights the potential of low-cost, non-cleanroom manufacturing techniques to produce high-performance microfluidic devices, thereby expanding their accessibility and applicability in various industrial and research settings. The integration of a continuous magnet, as opposed to segmented magnets in previous designs, was identified as a key factor in enhancing magnetic separation efficiency.

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Havelka, Ondřej, Martin Cvek, Michal Urbánek, Dariusz Łukowiec, Darina Jašíková, Michal Kotek, Miroslav Černík, Vincenzo Amendola y Rafael Torres-Mendieta. "On the Use of Laser Fragmentation for the Synthesis of Ligand-Free Ultra-Small Iron Nanoparticles in Various Liquid Environments". Nanomaterials 11, n.º 6 (10 de junio de 2021): 1538. http://dx.doi.org/10.3390/nano11061538.

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Traditionally, the synthesis of nanomaterials in the ultra-small size regime (1–3 nm diameter) has been linked with the employment of excessive amounts of hazardous chemicals, inevitably leading to significant environmentally detrimental effects. In the current work, we demonstrate the potential of laser fragmentation in liquids (LFL) to produce highly pure and stable iron ultra-small nanoparticles. This is carried out by reducing the size of carbonyl iron microparticles dispersed in various polar solvents (water, ethanol, ethylene glycol, polyethylene glycol 400) and liquid nitrogen. The explored method enables the fabrication of ligand-free iron oxide ultra-small nanoparticles with diameter in the 1–3 nm range, a tight size distribution, and excellent hydrodynamic stability (zeta potential > 50 mV). The generated particles can be found in different forms, including separated ultra-small NPs, ultra-small NPs forming agglomerates, and ultra-small NPs together with zero-valent iron, iron carbide, or iron oxide NPs embedded in matrices, depending on the employed solvent and their dipolar moment. The LFL technique, aside from avoiding chemical waste generation, does not require any additional chemical agent, other than the precursor microparticles immersed in the corresponding solvent. In contrast to their widely exploited chemically synthesized counterparts, the lack of additives and chemical residuals may be of fundamental interest in sectors requiring colloidal stability and the largest possible number of chemically active sites, making the presented pathway a promising alternative for the clean design of new-generation nanomaterials.

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Tesis sobre el tema "Iron oxide microparticles"

Akhtar, Asim. "Molecular magnetic resonance imaging of vascular inflammation using microparticles of iron oxide". Thesis, University of Oxford, 2010. http://ora.ox.ac.uk/objects/uuid:12bf8e4f-2909-4715-a6fe-bf42d9d8355a.

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One approach that has demonstrated success in the field of molecular imaging utilizes microparticles of iron oxide (MPIO) conjugated to specific antibodies and/or peptides to provide contrast effects on MRI in relation to the molecular expression of a specified target. The experimental aims of this thesis were 1) to investigate the ability of VCAM-1 and P-selectin targeted MPIO to detect the expression of VCAM-1 and P-selectin on the activated endothelium in-vitro and in-vivo in mouse models of renal and cerebral ischemia reperfusion injury, and 2) develop a novel contrast agent for imaging αvβ3-integrin expression in angiogenesis using RGD peptide conjugated MPIO (RGD-MPIO) in-vitro. MPIO (1.0 µm) were conjugated to monoclonal antibodies against VCAM-1 (VCAM-MPIO) or P-selectin (PSEL-MPIO). In vitro, MPIO bound in a dose-dependent manner to tumor necrosis factor (TNF)-alpha stimulated sEND-1 endothelial cells when conjugated to VCAM-1 (R² = 0.88, P<0.01) and P-selectin antibodies (R² = 0.93, P<0.01), reflecting molecular VCAM-1 and P-selectin mRNA and protein expression. Mice subjected to unilateral, transient (30 minutes) renal ischemia and subsequent reperfusion received intravenous VCAM-MPIO and PSEL-MPIO (4.5 mg iron/kg body weight). In ischemic kidneys, MR related contrast effects of VCAM-MPIO were 4-fold higher than unclamped kidneys (P<0.01) and 1.5-fold higher than clamped kidneys of PSEL-MPIO injected mice (P<0.05). VCAM-MPIO binding was less evident in IRI kidneys pre-treated with VCAM-1 antibody (P<0.001). VCAM-1 mRNA expression and VCAM-MPIO contrast volume were highly correlated (R² = 0.901, P<0.01), indicating that quantification of contrast volume reflected renal VCAM-1 transcription. In mice subjected to cerebral ischemia, contrast volume was 11-fold greater in animals injected with VCAM-MPIO versus control IgG-MPIO (P<0.05). Finally, S-nitroso-N-acetylpenicillamine (SNAP) stimulated HUVEC-C cells, which express αvβ3-integrin, showed 44-fold greater RGD-MPIO binding than unstimulated cells (P<0.001) and 4-fold greater RGD-MPIO binding than SNAP stimulated cells blocked with soluble RGD peptide (P<0.001) in-vitro. This thesis demonstrated that targeted MPIO exhibited contrast effects that defined and quantified the molecular expression of specific targets through the use of high-resolution MRI in in-vitro and in-vivo models of vascular inflammation.

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Yan, Huan. "MICRO- AND NANO-MATERIALS FOR DRUG DELIVERY AND BIOIMAGING APPLICATIONS". Kent State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=kent1428155172.

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Picot, Audrey. "Develοpment οf a theranοstic agent fοr micrοthrοmbοsis during ischemic strοke". Electronic Thesis or Diss., Normandie, 2024. http://www.theses.fr/2024NORMC418.

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De nouvelles études suggèrent que l'accident vasculaire cérébral ischémique est fréquemment associé à la formation de microthrombi dans la microcirculation corticale. Ces microthrombi sont associés à une augmentation de la taille de la lésion, à un déclin cognitif et à la démence. Il est difficile de prendre en charge ces microthrombi car les méthodes d'imagerie actuelles ne permettent pas de les détecter. Pour y remédier, un nouvel agent théranostique a été développé, les IO@PDA@tPA, combinant des microparticules d'oxyde de fer (IO) enrobées de polydopamine (PDA) et conjuguées avec l’activateur tissulaire du plasminogène (r-tPA). Ce nouvel agent a montré son efficacité in vitro, non seulement sur la lyse de caillots, mais également sur les espèces réactives de l'oxygène qui sont significativement moins exprimées par les neurones soumis à une privation d'oxygène et de glucose. In vivo, l'administration des IO@PDA@tPA à un quart de la dose standard de r-tPA a permis la visualisation et la dégradation des microthrombi, détectées par imagerie par résonance magnétique (IRM) pondérée en T2*. Ce traitement a réduit de manière significative la taille de la lésion et favorisé la recanalisation 24 heures après le début de l'AVC. Dans un modèle d'AVC ischémique chez la souris hyperglycémique, les IO@PDA@tPA ont montré une efficacité similaire à celle du r-tPA sans augmenter le risque hémorragique, une complication courante du r-tPA libre. De plus, une récupération fonctionnelle complète a été observée cinq jours après l'AVC. Ainsi, les IO@PDA@tPA représentent un outil théranostique prometteur pour cibler les microthrombi cérébraux, réduire la dose de r-tPA nécessaire et les effets secondaires associés
There is emerging evidence suggesting that ischemic stroke is frequently associated with the formation of microthrombi in downstream microcirculation. These microthrombi are associated with increased lesion size, cognitive decline, and dementia. Unfortunately, these microthrombi are difficult to detect with current imaging methods. To address this, a novel theranostic agent was developed, IO@PDA@tPA, combining iron oxide microparticles (IO) coated with polydopamine (PDA) and conjugated with recombinant tissue-type plasminogen activator (r-tPA). This agent exhibits in vitro clot lysis activity and reduces reactive oxygen species in neurons under oxygen-glucose deprivation. In vivo, administration of IO@PDA@tPA at one-quarter of the standard r-tPA dose enabled microthrombi visualization and degradation as detected by T2*-weighted magnetic resonance imaging (MRI). This treatment significantly reduced lesion size and promoted recanalization 24 hours after stroke onset. In a hyperglycemic mouse model of IS, the agent showed similar efficacy compared to r-tPA without increasing hemorrhagic risk, a common complication of free r-tPA. Additionally, full functional recovery was observed within five days post-stroke. Thus, IO@PDA@tPA represents a promising theranostic tool for targeting cerebral microthrombi, reducing the required r-tPA dose and associated side effects

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Pedron, Swannie. "Ιmagerie mοléculaire utilisant des micrοparticules d'οxyde de fer pοur la détectiοn de l'inflammatiοn cardiaque (par Ιmagerie par Résοnance Μagnétique) et de l'inflammatiοn pulmοnaire (par Ιmagerie à Ρarticules Μagnétiques - ΙΡΜ οu ΜΡΙ)". Electronic Thesis or Diss., Normandie, 2024. http://www.theses.fr/2024NORMC419.

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Les méthodes d'imagerie classiques comme l'IRM cardiaque et le scanner thoracique sont couramment utilisées pour le diagnostic des maladies cardiovasculaires et pulmonaires. Cependant, elles ne permettent que l’identification des retentissements fonctionnels et anatomiques, et la détection de la composante inflammatoire impliquée dans ces pathologies reste perfectible. Dans ces travaux de thèse, nous développons une nouvelle approche d’imagerie moléculaire appelée « immuno-IRM », qui cible les molécules d'adhésion endothéliales impliquées dans le recrutement des leucocytes vers les sites inflammatoires. En utilisant des microparticules d’oxyde de fer conjuguées à un anticorps VCAM-1 (MPIO@αVCAM-1), nous avons évalué la capacité de l’immuno-IRM à détecter in vivo et de manière spécifique l’inflammation cardiaque dans des modèles animaux de dysfonction cardiaque septique et de myocardite auto-immune expérimentale (EAM). Nous comparons notamment l’efficacité de l’immuno-IRM pour révéler l’inflammation cardiaque par rapport au rehaussement tardif au gadolinium, utilisé en clinique et considéré comme la méthode de référence (« gold standard ») pour le diagnostic de la myocardite. Dans la deuxième partie de cette thèse, nous avons développé l’utilisation d’un nouvel appareil d’imagerie appelé « Imagerie à Particules Magnétiques » (IPM), qui repose sur la détection de particules d’oxyde de fer pour créer des images corps entier, sans utiliser de rayonnements ionisants. À travers des modèles de sepsis et de maladie respiratoire infectieuse, nous avons montré que l’IPM couplée à l’utilisation de MPIO@αVCAM-1 était un outil rapide, sensible et non invasif permettant la détection de l’inflammation pulmonaire. Nos données apportent les premiers éléments permettant d’envisager, à terme, l’application de l’immuno-IRM et de l’IPM pour le diagnostic de pathologies inflammatoires cardiaques et pulmonaires
Conventional imaging methods such as cardiac MRI and thoracic CT scans are commonly used for diagnosing cardiovascular and pulmonary diseases. However, they only identify functional and anatomical abnormalities, and detecting the inflammatory component involved in these pathologies remains challenging. In this thesis, we develop a new molecular imaging approach called "immunoMRI," which targets endothelial adhesion molecules involved in recruiting leukocytes to inflammatory sites. Using iron oxide microparticles conjugated with a VCAM-1 antibody (MPIO@αVCAM-1), we assessed the ability of immuno-MRI to specifically detect cardiac inflammation in vivo in animal models of septic cardiac dysfunction and experimental autoimmune myocarditis (EAM). We also compared the effectiveness of immuno-MRI in detecting cardiac inflammation to late gadolinium enhancement, which is used in clinical practice and considered the gold standard for myocarditis diagnosis. In the second part of this work, we developed the use of a new imaging device called "Magnetic Particle Imaging" (MPI), which detects iron oxide particles to create whole-body images without using ionizing radiation. Through models of sepsis and infectious respiratory disease, we demonstrated that MPI coupled with MPIO@αVCAM-1 is a rapid, sensitive, and non-invasive tool for detecting pulmonary inflammation. Our data provide the first evidence suggesting the potential future application of immuno-MRI and MPI for diagnosing inflammatory cardiac and pulmonary conditions

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CHUANG, MENG-HAN y 莊孟翰. "Evaluation of chitosan derivative microparticles encapsulating superparamagnetic iron oxide and doxorubicin as a pH-sensitive delivery carrier on hepatic carcinoma treatment". Thesis, 2016. http://ndltd.ncl.edu.tw/handle/59636318427197387350.

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碩士
國立臺灣科技大學
醫學工程研究所
105
A novel pH-sensitive drug delivery micro-particles, based on N-palmitoyl chitosan (NPCS) using electrospray technology to transport the superparamagnetic iron oxide (SPIO) and anticancer drug doxorubicin (DOX) was developed. The characteristic of NPCS was characterized by nuclear magnetic resonance(NMR) and swelling testing, it showed that modified chitosan had pH-targeted property. The morphology and size of the DOX-SPIO/NPCS micro-particles were investigated by transmission and scanning electron microscopy. Based on using different vaporization properties of electrospray solvent showed formic acid/acetone co-solvent has better particle forming ability than formic acid solvent alone in suspension collection. The micro-particles had the diameters in 185 ± 87 nm. Materials surface properties of DOX-SPIO/NPCS micro-particles, was confirmed using Fourier Transform Infrared Spectroscopy (FTIR) to make sure that using electrospray technology will not change the materials properties. Transmission electron microscopy (TEM) and nuclear magnetic resonance T2 imaging(NMRI) confirmed the SPIO in composite micro-particles. In drug release profile, we found the DOX-SPIO/NPCS drug delivery micro-particles was accelerated in acidic environment (pH 6.5). Micro-particles in cytotoxicity assay (MTT assay) showed that DOX-SPIO/NPCS micro-particles has better anti-tumor ability than that of DOX freeform. Additionally, micro-particles were loaded 5 μg/mL DOX in acidic environment (pH 6.5) to kill HepG2 cell effectively. The DOX-SPIO/NPCS micro-particles could be potentially applied as pH sensitive drug delivery system for Hepatic carcinoma therapy.

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Chen, Shiu-Shin y 陳旭心. "A preparation of Disulfiram and superparamagnetic iron oxide encapsulating alginate microparticles and their in vitro efficacy of hyperthermic chemotherapy toward ovarian cancer cells". Thesis, 2019. http://ndltd.ncl.edu.tw/handle/3j57q2.

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Le, Renard Pol-Edern. "Injectable formulations forming an implant in situ as vehicle of silica microparticles embedding superparamagnetic iron oxide nanoparticles for the local, magnetically mediated hyperthermia treatment of solid tumors". Phd thesis, 2011. http://tel.archives-ouvertes.fr/tel-00709676.

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Cette thèse présente les travaux de développement de formulations injectables capables de se solidifier in situ, formant ainsi un implant piégeant des microparticules magnétiques en vue du traitement de tumeurs par induction magnétique d'une hyperthermie locale modérée. Nous exposons tout d'abord le contexte physique, biologique et clinique de l'hyperthermie comme traitement anticancéreux, particulièrement des modalités électromagnétiques. Les performances in vitro et in vivo des matériaux et formulations sont alors présentées. L'objet du chapitre suivant est la caractérisation des propriétés physicochimiques, magnétiques, et chauffantes, dans un champ magnétique alternatif (115 kHz, 9 - 12 mT), des microparticules de silice renfermant des nanoparticules d'oxyde de fer superparamagnétiques (SPIONs) et de deux de leurs formulations: un hydrogel d'alginate de sodium et un organogel de poly(éthylène-co-alcool vinylique) dans le diméthylsulfoxide. Finalement, nous présentons le potentiel thérapeutique de 20 minutes d'hyperthermie locale induite après injection de l'organogel superparamagnétique dans un modèle murin sous-cutané de tumeurs nécrosantes de colocarcinome humain.

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Capítulos de libros sobre el tema "Iron oxide microparticles"

McAteer, Martina A., Constantin von Zur Muhlen, Daniel C. Anthony, Nicola R. Sibson y Robin P. Choudhury. "Magnetic Resonance Imaging of Brain Inflammation Using Microparticles of Iron Oxide". En Methods in Molecular Biology, 103–15. Totowa, NJ: Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-901-7_7.

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Actas de conferencias sobre el tema "Iron oxide microparticles"

Mathieu, Jean-Baptiste y Sylvain Martel. "Magnetic Steering of Iron Oxide Microparticles Using Propulsion Gradient Coils in MRI". En Conference Proceedings. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2006. http://dx.doi.org/10.1109/iembs.2006.259818.

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Akın, Deniz, Arzu Yakar y Ufuk Gündüz. "The effect of ultrasonication on the size and morphology of iron oxide - chitosan nano and microparticles". En 3RD INTERNATIONAL ADVANCES IN APPLIED PHYSICS AND MATERIALS SCIENCE CONGRESS. AIP, 2013. http://dx.doi.org/10.1063/1.4849220.

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Leng, Rui, Oliver Uitz, Zoubeida Ounaies y Carolyn Seepersad. "Design and Characterization of a Multilayered Multifield-Actuated Polymer Unimorph". En ASME 2021 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/smasis2021-68238.

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Abstract In this study, we design, fabricate and characterize a novel unimorph-like structure in which a shape memory polymer (SMP) is actuated using a magneto-active elastomer (MAE), resulting in contactless and large deformation shape change. The constituent materials are: a two-part elastomer, iron oxide microparticles, and a rapid cure epoxy. Combining the elastomer with the iron oxide particles results in an MAE actuator, such that application of an external magnetic field induces dipoles in the iron oxide particles, resulting in the actuation of the MAE. The shape memory epoxy polymers are deformed at an elevated temperature and cooled to lock-in the temporary programmed shape. Subsequent exposure to elevated temperature can then recover a permanent geometry. In a first step, the layered unimorph structure is fabricated using casting techniques in which the SMP serves as the ‘passive’ substrate, and the MAE is cast on top of this substrate or joined post-processing using adhesives. To demonstrate shape change, the unimorph is heated beyond the transition temperature of the epoxy, and a magnetic field is applied to deform the structure. Upon cooling, the shape change is locked into place. This configuration serves as proof-of-concept that the proposed magnetically-responsive polymers are capable of eliciting the shape change of an SMP through bending in response to an external magnetic stimulus. After demonstrating feasibility, the next step is to use additive manufacturing (AM) to produce both the SMP and MAE by developing and tuning MAE and SMP resin formulations for printability. Printability is assessed by characterizing the viscosities, effective yield stress, gelation times, and extent of cure of the material formulations. The bending response of the layered structure is characterized as a function of magnetic field, material composition, geometric parameters, and AM process settings. The outcome of this research is to enable AM of smart materials and devices that can monitor and adapt to their environment. The medical device industry in particular stands to benefit from customizable devices that adapt their shape for particular patients, diseases, and/or stage of healing.

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