Artículos de revistas sobre el tema "IPSC-derived neurons"
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Allison, Reilly L., Jacob W. Adelman, Jenica Abrudan, Raul A. Urrutia, Michael T. Zimmermann, Angela J. Mathison y Allison D. Ebert. "Microglia Influence Neurofilament Deposition in ALS iPSC-Derived Motor Neurons". Genes 13, n.º 2 (27 de enero de 2022): 241. http://dx.doi.org/10.3390/genes13020241.
Texto completoMatsui, Toshikatsu, Norimasa Miyamoto, Fumiyo Saito y Tadahiro Shinozawa. "Molecular Profiling of Human Induced Pluripotent Stem Cell-Derived Cells and their Application for Drug Safety Study". Current Pharmaceutical Biotechnology 21, n.º 9 (9 de junio de 2020): 807–28. http://dx.doi.org/10.2174/1389201021666200422090952.
Texto completoAvazzadeh, Sahar, Jara Maria Baena, Cameron Keighron, Yajaira Feller-Sanchez y Leo R. Quinlan. "Modelling Parkinson’s Disease: iPSCs towards Better Understanding of Human Pathology". Brain Sciences 11, n.º 3 (14 de marzo de 2021): 373. http://dx.doi.org/10.3390/brainsci11030373.
Texto completoGuyett, Paul, Mike Hendrickson y Kurt Laha. "CNS Drug Discovery Using iPSC-Derived Neurons". Genetic Engineering & Biotechnology News 38, n.º 20 (15 de noviembre de 2018): 14–15. http://dx.doi.org/10.1089/gen.38.20.08.
Texto completoIchise, Eisuke, Tomohiro Chiyonobu, Mitsuru Ishikawa, Yasuyoshi Tanaka, Mami Shibata, Takenori Tozawa, Yoshihiro Taura et al. "Impaired neuronal activity and differential gene expression in STXBP1 encephalopathy patient iPSC-derived GABAergic neurons". Human Molecular Genetics 30, n.º 14 (7 de mayo de 2021): 1337–48. http://dx.doi.org/10.1093/hmg/ddab113.
Texto completoHedegaard, Anne, Jimena Monzón-Sandoval, Sarah E. Newey, Emma S. Whiteley, Caleb Webber y Colin J. Akerman. "Pro-maturational Effects of Human iPSC-Derived Cortical Astrocytes upon iPSC-Derived Cortical Neurons". Stem Cell Reports 15, n.º 1 (julio de 2020): 38–51. http://dx.doi.org/10.1016/j.stemcr.2020.05.003.
Texto completoMiletta, Maria Consolata y Tamas L. Horvath. "Patient-Derived iPSC-Hypothamic Neurons: The Ultimate Protocol". Cell Stem Cell 22, n.º 5 (mayo de 2018): 615–16. http://dx.doi.org/10.1016/j.stem.2018.04.019.
Texto completoLee, Sebum y Eric J. Huang. "Modeling ALS and FTD with iPSC-derived neurons". Brain Research 1656 (febrero de 2017): 88–97. http://dx.doi.org/10.1016/j.brainres.2015.10.003.
Texto completoVangeel, Laura. "TRP Channel Function in iPSC-Derived Sensory Neurons". Biophysical Journal 112, n.º 3 (febrero de 2017): 135a. http://dx.doi.org/10.1016/j.bpj.2016.11.750.
Texto completoPierson, Tyler M., Yogesh K. Kushwaha, Hiral Oza y Maria G. Otero. "Modeling CLN6 with IPSC-derived neurons and glia". Molecular Genetics and Metabolism 138, n.º 2 (febrero de 2023): 107269. http://dx.doi.org/10.1016/j.ymgme.2022.107269.
Texto completoCordella, Federica, Laura Ferrucci, Chiara D’Antoni, Silvia Ghirga, Carlo Brighi, Alessandro Soloperto, Ylenia Gigante, Davide Ragozzino, Paola Bezzi y Silvia Di Angelantonio. "Human iPSC-Derived Cortical Neurons Display Homeostatic Plasticity". Life 12, n.º 11 (14 de noviembre de 2022): 1884. http://dx.doi.org/10.3390/life12111884.
Texto completoImran, Saima Jalil, Barbora Vagaska, Jan Kriska, Miroslava Anderova, Mario Bortolozzi, Gino Gerosa, Patrizia Ferretti y Radim Vrzal. "Aryl Hydrocarbon Receptor (AhR)-Mediated Signaling in iPSC-Derived Human Motor Neurons". Pharmaceuticals 15, n.º 7 (4 de julio de 2022): 828. http://dx.doi.org/10.3390/ph15070828.
Texto completoImamura, Keiko, Yuishin Izumi, Akira Watanabe, Kayoko Tsukita, Knut Woltjen, Takuya Yamamoto, Akitsu Hotta et al. "The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis". Science Translational Medicine 9, n.º 391 (24 de mayo de 2017): eaaf3962. http://dx.doi.org/10.1126/scitranslmed.aaf3962.
Texto completoMortensen, Christina, Nanna Elman Andersen y Tore Bjerregaard Stage. "Bridging the Translational Gap in Chemotherapy-Induced Peripheral Neuropathy with iPSC-Based Modeling". Cancers 14, n.º 16 (15 de agosto de 2022): 3939. http://dx.doi.org/10.3390/cancers14163939.
Texto completoLeventoux, Nicolas, Satoru Morimoto, Kent Imaizumi, Yuta Sato, Shinichi Takahashi, Kyoko Mashima, Mitsuru Ishikawa et al. "Human Astrocytes Model Derived from Induced Pluripotent Stem Cells". Cells 9, n.º 12 (13 de diciembre de 2020): 2680. http://dx.doi.org/10.3390/cells9122680.
Texto completoBachmann, Sarah, Jenice Linde, Michael Bell, Marc Spehr, Hans Zempel y Geraldine Zimmer-Bensch. "DNA Methyltransferase 1 (DNMT1) Shapes Neuronal Activity of Human iPSC-Derived Glutamatergic Cortical Neurons". International Journal of Molecular Sciences 22, n.º 4 (18 de febrero de 2021): 2034. http://dx.doi.org/10.3390/ijms22042034.
Texto completoMcCready, Fraser P., Sara Gordillo-Sampedro, Kartik Pradeepan, Julio Martinez-Trujillo y James Ellis. "Multielectrode Arrays for Functional Phenotyping of Neurons from Induced Pluripotent Stem Cell Models of Neurodevelopmental Disorders". Biology 11, n.º 2 (16 de febrero de 2022): 316. http://dx.doi.org/10.3390/biology11020316.
Texto completoVerheyen, An, Annick Diels, Joyce Dijkmans, Tutu Oyelami, Giulia Meneghello, Liesbeth Mertens, Sofie Versweyveld et al. "Using Human iPSC-Derived Neurons to Model TAU Aggregation". PLOS ONE 10, n.º 12 (31 de diciembre de 2015): e0146127. http://dx.doi.org/10.1371/journal.pone.0146127.
Texto completoLiu, Jing, Katarzyna A. Kościelska, Zhengyu Cao, Susan Hulsizer, Natalie Grace, Gaela Mitchell, Catherine Nacey et al. "Signaling defects in iPSC-derived fragile X premutation neurons". Human Molecular Genetics 21, n.º 17 (28 de mayo de 2012): 3795–805. http://dx.doi.org/10.1093/hmg/dds207.
Texto completoFyfe, Ian. "Mutation-specific amyloid-β processing in iPSC-derived neurons". Nature Reviews Neurology 15, n.º 6 (29 de abril de 2019): 310. http://dx.doi.org/10.1038/s41582-019-0195-z.
Texto completoSchwartzentruber, Jeremy, Stefanie Foskolou, Helena Kilpinen, Julia Rodrigues, Kaur Alasoo, Andrew J. Knights, Minal Patel et al. "Molecular and functional variation in iPSC-derived sensory neurons". Nature Genetics 50, n.º 1 (11 de diciembre de 2017): 54–61. http://dx.doi.org/10.1038/s41588-017-0005-8.
Texto completoHalliwell, Robert F., Hamed Salmanzadeh, Leanne Coyne y William S. Cao. "An Electrophysiological and Pharmacological Study of the Properties of Human iPSC-Derived Neurons for Drug Discovery". Cells 10, n.º 8 (31 de julio de 2021): 1953. http://dx.doi.org/10.3390/cells10081953.
Texto completoKaifer, Kevin A., Eric Villalón, Benjamin S. O'Brien, Samantha L. Sison, Caley E. Smith, Madeline E. Simon, Jose Marquez et al. "AAV9-mediated delivery of miR-23a reduces disease severity in Smn2B/−SMA model mice". Human Molecular Genetics 28, n.º 19 (20 de mayo de 2019): 3199–210. http://dx.doi.org/10.1093/hmg/ddz142.
Texto completoSmethurst, Phillip, Emmanuel Risse, Giulia E. Tyzack, Jamie S. Mitchell, Doaa M. Taha, Yun-Ru Chen, Jia Newcombe, John Collinge, Katie Sidle y Rickie Patani. "Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis". Brain 143, n.º 2 (1 de febrero de 2020): 430–40. http://dx.doi.org/10.1093/brain/awz419.
Texto completoVanHook, Annalisa M. "Cholesterol and Alzheimer’s disease". Science Signaling 12, n.º 575 (2 de abril de 2019): eaax4932. http://dx.doi.org/10.1126/scisignal.aax4932.
Texto completoHiramatsu, Satoe, Asuka Morizane, Tetsuhiro Kikuchi, Daisuke Doi, Kenji Yoshida y Jun Takahashi. "Cryopreservation of Induced Pluripotent Stem Cell-Derived Dopaminergic Neurospheres for Clinical Application". Journal of Parkinson's Disease 12, n.º 3 (5 de abril de 2022): 871–84. http://dx.doi.org/10.3233/jpd-212934.
Texto completoVoronkov, Dmitry N., Alla V. Stavrovskaya, Anastasia S. Guschina, Artyom S. Olshansky, Olga S. Lebedeva, Artyom V. Eremeev y Maria A. Lagarkova. "Morphological Characterization of Astrocytes in a Xenograft of Human iPSC-Derived Neural Precursor Cells". Acta Naturae 14, n.º 3 (29 de octubre de 2022): 100–108. http://dx.doi.org/10.32607/actanaturae.11710.
Texto completoZhao, Helen, Guy Perkins, Hang Yao, David Callacondo, Otto Appenzeller, Mark Ellisman, Albert R. La Spada y Gabriel G. Haddad. "Mitochondrial dysfunction in iPSC-derived neurons of subjects with chronic mountain sickness". Journal of Applied Physiology 125, n.º 3 (1 de septiembre de 2018): 832–40. http://dx.doi.org/10.1152/japplphysiol.00689.2017.
Texto completoRakovic, Aleksandar, Philip Seibler y Christine Klein. "iPS models of Parkin and PINK1". Biochemical Society Transactions 43, n.º 2 (1 de abril de 2015): 302–7. http://dx.doi.org/10.1042/bst20150010.
Texto completoKathuria, Annie, Bradley Watmuff, Kara Lopez-Lengowski, Donna McPhie, Bruce Cohen y Rakesh Karmacharya. "Dendritic Spine Differences in iPSC-Derived Cortical Neurons in Schizophrenia". Biological Psychiatry 89, n.º 9 (mayo de 2021): S33—S34. http://dx.doi.org/10.1016/j.biopsych.2021.02.102.
Texto completoCarvalhas-Almeida, C., L. Pereira de Almeida, C. Cavadas, P. Perdigão y A. R. Álvaro. "Insomnia patient-derived iPSC neurons with potential for disease modeling". Sleep Medicine 100 (diciembre de 2022): S124—S125. http://dx.doi.org/10.1016/j.sleep.2022.05.343.
Texto completoNakazawa, Takanobu. "Pharmacological studies using iPSC-derived neurons from patients with schizophrenia". Folia Pharmacologica Japonica 156, n.º 4 (2021): 220–23. http://dx.doi.org/10.1254/fpj.21003.
Texto completoSaavedra, Lorena, Thomas Portman, Daniel Haag, Jonathan Davila, Timothy J. Shafer, Kathleen Wallace, Theresa Freudenrich y Hui Liu. "In vitro neurotoxicity testing using functional human iPSC-derived neurons". Journal of Pharmacological and Toxicological Methods 111 (septiembre de 2021): 106976. http://dx.doi.org/10.1016/j.vascn.2021.106976.
Texto completoNegraes, P. D., F. R. Cugola, R. H. Herai, C. A. Trujillo, A. S. Cristino, T. Chailangkarn, A. R. Muotri y V. Duvvuri. "Modeling anorexia nervosa: transcriptional insights from human iPSC-derived neurons". Translational Psychiatry 7, n.º 3 (marzo de 2017): e1060-e1060. http://dx.doi.org/10.1038/tp.2017.37.
Texto completoGirardin, Sophie, Blandine Clément, Stephan J. Ihle, Sean Weaver, Jana B. Petr, José C. Mateus, Jens Duru et al. "Topologically controlled circuits of human iPSC-derived neurons for electrophysiology recordings". Lab on a Chip 22, n.º 7 (2022): 1386–403. http://dx.doi.org/10.1039/d1lc01110c.
Texto completoWong, Ching-On y Kartik Venkatachalam. "Motor neurons from ALS patients with mutations in C9ORF72 and SOD1 exhibit distinct transcriptional landscapes". Human Molecular Genetics 28, n.º 16 (20 de mayo de 2019): 2799–810. http://dx.doi.org/10.1093/hmg/ddz104.
Texto completoBehne, Robert, Julian Teinert, Miriam Wimmer, Angelica D’Amore, Alexandra K. Davies, Joseph M. Scarrott, Kathrin Eberhardt et al. "Adaptor protein complex 4 deficiency: a paradigm of childhood-onset hereditary spastic paraplegia caused by defective protein trafficking". Human Molecular Genetics 29, n.º 2 (9 de enero de 2020): 320–34. http://dx.doi.org/10.1093/hmg/ddz310.
Texto completoChen, I.-Cheng, Kuo-Hsuan Chang, Yi-Jing Chen, Yi-Chun Chen, Guey-Jen Lee-Chen y Chiung-Mei Chen. "Pueraria lobata and Daidzein Reduce Cytotoxicity by Enhancing Ubiquitin-Proteasome System Function in SCA3-iPSC-Derived Neurons". Oxidative Medicine and Cellular Longevity 2019 (7 de octubre de 2019): 1–18. http://dx.doi.org/10.1155/2019/8130481.
Texto completoOakley, Derek H., Mirra Chung, Naomi Klickstein, Caitlin Commins, Bradley T. Hyman y Matthew P. Frosch. "The Alzheimer Disease-Causing Presenilin-1 L435F Mutation Causes Increased Production of Soluble Aβ43 Species in Patient-Derived iPSC-Neurons, Closely Mimicking Matched Patient Brain Tissue". Journal of Neuropathology & Experimental Neurology 79, n.º 6 (4 de abril de 2020): 592–604. http://dx.doi.org/10.1093/jnen/nlaa025.
Texto completoAlari, Valentina, Paolo Scalmani, Paola Francesca Ajmone, Sara Perego, Sabrina Avignone, Ilaria Catusi, Paola Adele Lonati et al. "Histone Deacetylase Inhibitors Ameliorate Morphological Defects and Hypoexcitability of iPSC-Neurons from Rubinstein-Taybi Patients". International Journal of Molecular Sciences 22, n.º 11 (28 de mayo de 2021): 5777. http://dx.doi.org/10.3390/ijms22115777.
Texto completoBrot, Sébastien, Nabila Pyrenina Thamrin, Marie-Laure Bonnet, Maureen Francheteau, Maëlig Patrigeon, Laure Belnoue y Afsaneh Gaillard. "Long-Term Evaluation of Intranigral Transplantation of Human iPSC-Derived Dopamine Neurons in a Parkinson’s Disease Mouse Model". Cells 11, n.º 10 (10 de mayo de 2022): 1596. http://dx.doi.org/10.3390/cells11101596.
Texto completoChao, Chuan-Chuan, Po-Wen Shen, Tsai-Yu Tzeng, Hsing-Jien Kung, Ting-Fen Tsai y Yu-Hui Wong. "Human iPSC-Derived Neurons as A Platform for Deciphering the Mechanisms behind Brain Aging". Biomedicines 9, n.º 11 (7 de noviembre de 2021): 1635. http://dx.doi.org/10.3390/biomedicines9111635.
Texto completoHuang, Hsiang-Po, Wei Chiang, Lee Stone, Chun-Kai Kang, Ching-Yu Chuang y Hung-Chih Kuo. "Using human Pompe disease-induced pluripotent stem cell-derived neural cells to identify compounds with therapeutic potential". Human Molecular Genetics 28, n.º 23 (13 de septiembre de 2019): 3880–94. http://dx.doi.org/10.1093/hmg/ddz218.
Texto completoRanjan, Vivek Damodar, Lifeng Qiu, Jolene Wei-Ling Lee, Xuelong Chen, Se Eun Jang, Chou Chai, Kah-Leong Lim et al. "A microfiber scaffold-based 3D in vitro human neuronal culture model of Alzheimer's disease". Biomaterials Science 8, n.º 17 (2020): 4861–74. http://dx.doi.org/10.1039/d0bm00833h.
Texto completoBurman, Richard J., Lauren M. Watson, Danielle C. Smith, Joseph V. Raimondo, Robea Ballo, Janine Scholefield, Sally A. Cowley, Matthew J. A. Wood, Susan H. Kidson y Leslie J. Greenberg. "Molecular and electrophysiological features of spinocerebellar ataxia type seven in induced pluripotent stem cells". PLOS ONE 16, n.º 2 (24 de febrero de 2021): e0247434. http://dx.doi.org/10.1371/journal.pone.0247434.
Texto completoEllerby, Lisa, Sicheng Song, Sean Mooney, Stephen Scheeler y Swati Naphade. "GENOMIC ANALYSIS OF HUMAN ISOGENIC APOE IPSC-DERIVED INHIBITORY GABAERGIC NEURONS". Innovation in Aging 3, Supplement_1 (noviembre de 2019): S621. http://dx.doi.org/10.1093/geroni/igz038.2315.
Texto completoBai, Xiaowen. "Stem Cell-Based Disease Modeling and Cell Therapy". Cells 9, n.º 10 (29 de septiembre de 2020): 2193. http://dx.doi.org/10.3390/cells9102193.
Texto completoOakley, Derek H., Naomi Klickstein, Caitlin Commins, Mirra Chung, Simon Dujardin, Rachel E. Bennett, Bradley T. Hyman y Matthew P. Frosch. "Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons". Journal of Neuroscience 41, n.º 19 (23 de abril de 2021): 4335–48. http://dx.doi.org/10.1523/jneurosci.2590-20.2021.
Texto completoLickfett, Selene, Carmen Menacho, Annika Zink, Narasimha Swamy Telugu, Mathias Beller, Sebastian Diecke, Sidney Cambridge y Alessandro Prigione. "High-content analysis of neuronal morphology in human iPSC-derived neurons". STAR Protocols 3, n.º 3 (septiembre de 2022): 101567. http://dx.doi.org/10.1016/j.xpro.2022.101567.
Texto completoMooree, Travis, Poulomee Bose, Jill Wood, Thomas Durcan y Alexey Pshezhetsky. "iPSC derived neurons of mucopolysaccharidosis III patients show pronounced synaptic defects". Molecular Genetics and Metabolism 135, n.º 2 (febrero de 2022): S85. http://dx.doi.org/10.1016/j.ymgme.2021.11.219.
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