Tesis sobre el tema "IPC device"
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Louison, Charles Davidson. "A biomedical device business plan for Medicraften Devices Inc. to develop a fluid medication dispenser". Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/36730.
Texto completoIncludes bibliographical references (leaf 32).
This thesis surrounds an analysis to understand what it would take for a company to successfully launch a prescription fluid dispensing device. This device would in theory be able to dispense medication at any time daily in correspondence to a patient's prescription. This thesis does not surround the actual development of a prototype, but gives a clear background into its technology. Other areas of research in this report include potential alliances and acquisitions of this company. This report gives a background into the target market, how the market will benefit from this device, and who the potential competitors of this device could be. Also explored are a potential advisory board for this company and how staff will be organized. Although the people on the advisory board and company's staff do exist, they are not actually involved in the conception of the thesis' device. This thesis uses techniques learned in management, engineering, and biomedical enterprise courses at MIT to give a real world case of how an effective biomedical device company can be formed and effectively managed.
by Charles Davidson Louison.
S.B.
Alley, Krista I. "Defining the Industrial Designer's Role in the ISO/IEC 62366 Standard". University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397235614.
Texto completoMohdzaini, Jefri 1976. "The characterization of the Analog Devices Inc. (ADI) magnetometer". Thesis, Massachusetts Institute of Technology, 2000. http://hdl.handle.net/1721.1/86535.
Texto completoIncludes bibliographical references (leaves 45-46).
by Jefri Mohdzaini.
M.Eng.
Alemayehu, Andargachew Desta. "Microwave Frequency Thin BST Film Based Tunable Shunt and Series Interdigital Capacitor Device Design". University of Dayton / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1304558851.
Texto completoBurchell, Stephen Michael. "Investigations of mixed-gas plasmas using a sheathing device for ICP-MS". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0020/MQ52880.pdf.
Texto completoLi, Heli. "RF LOW PASS FILTER DESIGN AND FABRICATION USING INTEGRATED PASSIVE DEVICE TECHNOLOGY". Master's thesis, University of Central Florida, 2006. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/4340.
Texto completoM.S.E.E.
School of Electrical Engineering and Computer Science
Engineering and Computer Science
Electrical Engineering
Mazur, David Christopher. "An Electrical Mine Monitoring System Utilizing the IEC 61850 Standard". Diss., Virginia Tech, 2013. http://hdl.handle.net/10919/52239.
Texto completoPh. D.
Teran-Escobar, Gerardo, David M. Tanenbaum, Eszter Voroshazi, Martin Hermenau, Kion Norrman, Matthew T. Lloyd, Yulia Galagan et al. "On the stability of a variety of organic photovoltaic devices by IPCE and in situ IPCE analyses – the ISOS-3 inter-laboratory collaboration". Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-139279.
Texto completoDieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich
Teran-Escobar, Gerardo, David M. Tanenbaum, Eszter Voroshazi, Martin Hermenau, Kion Norrman, Matthew T. Lloyd, Yulia Galagan et al. "On the stability of a variety of organic photovoltaic devices by IPCE and in situ IPCE analyses – the ISOS-3 inter-laboratory collaboration". Royal Society of Chemistry, 2012. https://tud.qucosa.de/id/qucosa%3A27818.
Texto completoDieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
Cayron, Audrey. "Intégration de dispositifs passifs 3D compacts et performants.Application à la réalisation d’une matrice de Butler 4×4 en bande Ka". Thesis, Toulouse, INSA, 2020. http://www.theses.fr/2020ISAT0006.
Texto completoThe complexity of embedded RF systems in consumer wireless applications is increasing, and requires to improve the integration of RF and microwave passive circuits. New solutions that offer more compactness and performance have to be developed, while maintaining a low manufacturing cost. Among Integrated Passive Devices (IPD) technologies, a 3-D technology has been developed at the LAAS CNRS and by 3DiS Technologies for several years. Results demonstrate that the manufactured solenoids exhibit high compactness and high-performance. This PhD thesis aims to develop the integration process of capacitors in order to evolve the technology towards the fabrication of complex passive RF functions.The manuscript is divided into three chapters. The first chapter reviews the technological processes that enable the manufacture of RF systems and highlights the challenges for integrating high-performance passive components. It also presents the advantages of a low-cost 3-D integration solution such as the one proposed. In the second chapter, we present the development of Metal Insulator Metal (MIM) capacitors. The characterization result show that capacitors present performances equivalent to those identified in the literature with high quality factors. We then manufacture two transformers matched to 50 ohms using capacitors. The technological process is described. The manufactured and measured circuits show that transmission losses are close to those obtained at the maximum available gain of the transformers. These results confirm the good performance of the developed capacitors since they introduce minimal losses for the manufactured circuits. No technological problems are encountered during the manufacturing of the two transformers, which validates the complete technological process for the integration of capacitors and solenoid.Based on these results, we present in the last chapter the development of a 4×4 Butler matrix dedicated to 5G beamforming applications. In a large bandwidth ranging from 24 GHz to 29 GHz, insertion losses for the four outputs of the matrix are under 3.5 dB and the phase difference between the outputs are reached with a deviation of less than 16°. The measured results are at the state of the art and overcome those of the existing IPD solutions, in particular for the occupied aera that does not exceed 0.84 mm2. These performances allow us to conclude on the potential of 3-D IPD technology to achieve an excellent compromise between integration density and performance
Doyle, Marc. "Comprehending the Safety Paradox and Privacy Concerns with Medical Device Remote Patient Monitoring". Diss., NSUWorks, 2019. https://nsuworks.nova.edu/gscis_etd/1090.
Texto completoJung, Hyun Chul. "Design And Fabrication Of Microfluidic Devices For Electrokinetic Studies". The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1213978561.
Texto completoAndersson, Dorothea. "Simulation of industrial control system field devices for cyber security". Thesis, KTH, Elkraftteknik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-202405.
Texto completoIndustriella informations- och styrsystem utgör en viktig delav vårt moderna samhälle, inte minst när det gäller kontroll och skydd avkritisk infrastruktur som elnät och vattenförsörjning. Det finns stora behov avatt säkerhetstesta dessa typer av system, vilket ofta är omöjligt iproduktionsmiljöer med realtidskrav som är erkänt känsliga för störningar, tilloch med från vanligt förekommande analysverktyg. Denna rapport presenterarhur vanliga komponenter i industriella informations- och styrsystem kansimuleras för att lura potentiella antagonister, och hur de kan användas ivirtualiserade styrsystem för cybersäkerhetsforskning. 8 olika komponentersimulerades med hjälp av Honeyd, och en generellt applicerbarsimuleringsmetodik utvecklades. Hur dessa simuleringar kan vidareutvecklasför att fungera som riktiga styrsystemskomponenter i virtualiserade miljöer harockså undersökts.
Rajan, Parthiban. "Novel Capacitive Sensors for Chemical and Physical Monitoring in Microfluidic Devices". Ohio University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1549449776383119.
Texto completoFields, Robert Eugene 1958. "Application of a quadrupole ion trap mass spectrometer to ICP-MS and the direct detection of x-rays using a charge-injection device". Diss., The University of Arizona, 1997. http://hdl.handle.net/10150/282314.
Texto completoWhite, Brad D. "Cathodoluminescence spectroscopy studies of aluminum gallium nitride and silicon device structures as a function of irradiation and processing". The Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=osu1141325302.
Texto completoYang, Kai. "Fabrication and characterization of silicon nanowires for devices applications compatible with low temperature (≤300 ˚C) flexible substrates". Thesis, Rennes 1, 2019. http://www.theses.fr/2019REN1S123.
Texto completoThe fabrication and characterization of silicon nanowires (SiNWs) at low temperature (≤300° C) has been focused for two mainstream approaches: spacer method and Solid Liquid Solid method. The feasibility of such silicon nanowires has been explored using two deposition technologies: conventional plasma enhanced deposition (PECVD) and inductively coupled plasma deposition (ICP CVD). The studies demonstrated the feasibility of silicon nanowires using the ICP CVD process. In addition, the electrical insulation properties of SiO2 layers and the fabrication of thin-film field effect transistors were demonstrated using ICP plasma deposition technology. Furthermore, indium catalyzed SLS SiNWs were fabricated for the first time at 250 °C. Synthesis of 3D SiNWs by SLS process from silicon substrates (monocrystalline or amorphous silicon thin film) has been demonstrated. The growth of nanowires is obtained under hydrogen plasma. Studies were conducted based on the thickness of indium deposited, duration and temperature of the hydrogen plasma. All these results were concluded originally and they enable the possibility of fabrication of SiNWs based electronic devices onto low temperature flexible substrates
Nick, Shawn. "An investigation approach to test protection intelligent electronic devices (IEDs) in IEC 61850 based substation automation systems (SAS) at station level". Thesis, Queensland University of Technology, 2014. https://eprints.qut.edu.au/74751/1/Shawn_Nick_Thesis.pdf.
Texto completoWistedt, Johan. "Digital secondary substations with auto-configuration of station monitoring through IEC 61850 and CIM". Thesis, Uppsala universitet, Elektricitetslära, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-360513.
Texto completoYalda, Riad y Miroslav Urosevic. "Automatic post-fault analysis based on disturbance data stored in substation devices : Approach towards the preventive maintenance". Thesis, KTH, Hälsoinformatik och logistik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-252823.
Texto completoDenna rapport studerar möjligheten att minimera oönskade underhållsarbeten och öka tillgången på strömförsörjning genom att möjliggöra förebyggande underhåll i kraftsystemet, utan att behöva göra ytterligare investeringar för sina befintliga system. Detta gjordes med hjälp av information från COMTRADE-filer (filer för inspelning av störningar) som skapades vid ett fel i elnätet. IEC 61850-standarden underlättar processen för att hämta och analysera störningsfilerna genom att standardisera sitt format och hur de lagras. Genom att skapa en programvarulösning som automatiskt läser och analyserar COMTRADE-filerna, kan försämrad prestanda hos strömsystemets utrustning detekteras och förebyggande underhåll föreslås. Resultatet av projektet är en mjukvarulösning som läser och analyserar COMTRADE-filer på ett automatiserat sätt. Programvaran identifierar felhändelser (fel start, sänd bryt-signal, brytare öppen, automatisk återstängnings kommando, strömbrytare stängd) från de inspelade signalerna med wavelettransformen som huvudmetod. Därefter beräknas driftstiderna för relä och brytare. De beräknade tiderna jämförs med tröskelvärden och varningar genereras om de överskrider tröskelvärdena.
Luwaca, Emmanuel. "Virtualization of a sensor node to enable the simulation of IEC 61850-based sampled value messages". Thesis, Cape Peninsula University of Technology, 2014. http://hdl.handle.net/20.500.11838/1179.
Texto completoThe IEC 61850 standard, “Communication networks and systems in substations” was promulgated to accommodate the need for a common communication platform within substations for devices from different vendors. The IEC 61850 standard proposes a substation automation architecture that is Ethernet-based, with a “station-bus” for protection devices within the substation and a “process bus” where raw data from the voltage and current transformers are published onto the data network using a device known as a Merging Unit. To date, most of the standardization efforts were focused at the station bus level where event-triggered messages are exchanged between the substation automation devices, commonly referred to as Intelligent Electronic Devices (IEDs). These messages are known as Generic Object Oriented Substation Event messages. Equipment from vendors to accommodate the “process bus” paradigm, however is still limited at present. The Centre for Substation Automation and Energy Management Systems was established within the Electrical Engineering Department at the Cape Peninsula University of Technology with one of its objectives being the development of equipment either for simulation or real-time purposes in compliance with the IEC 61850 standard. In order to fulfil this long-term objective of the Centre, an in-depth understanding of the IEC 61850 standard is required. This document details the efforts at acquiring the requisite knowledge base in support of the educational objectives of the Centre and the research project implements a simulation of a merging unit which is compliant with the functional behavior as stipulated by the standard. This limited functional implementation (i.e. non-real-time) of the merging unit, is achieved through the development of a virtualized data acquisition node capable of synthetic generation of waveforms, encoding of the data and publishing the data in a format compliant with the IEC 61850-9-2 sampled value message structure. This functional behavior of the virtual sensor node which was implemented has been validated against the behavior of a commercial device and the sampled value message structure is validated against the standard. The temporal behavior of the proposed device is commented upon. This research project forms the basis for future real-time implementation of a merging unit.
Netto, Ulisses Chemin. "Determinação de um parâmetro para monitoramento do desempenho de mensagens GOOSE do padrão IEC 61850 utilizadas em subestações de energia elétrica". Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/18/18154/tde-16102012-083711/.
Texto completoThe development and utilization of IEC 61850 standard changed the design and operation of electric power substations. The performance and reliability of the protection system depends on the data communication network. This research proposes a parameter for dimensioning and comparising the transfer time of Generic Object Oriented Substation Event (GOOSE) messages between different Intelligent Electronic Devices (IEDs). This parameter was obtained from experimental data related to the transfer time of GOOSE messages curve versus IEDs bandwidth percentage occupation. In this context, a laboratory structure was set up in order to carry out these experiments. This structure mainly consists of three IEDs, an Ethernet switch, three personal computers, a GPS Clock, fiber optic cables, unshielded twisted pair cables, as well as support software. The results show the existence of a characteristic threshold, different for each IED tested, after which the transfer time exceeded the total transmission time allowed for the IEC 61850 standard. Based on these results, a predictive bandwidth monitoring system was developed to supervise the IEDs bandwidth interface. The bandwidth measurement has a mean relative error of 0.55% regarding to the commercial software used for comparison. Finally, the forecasting made by the artificial neural network has a relative error of 3% for 91,30% of the samples used in test phase. In addition, that it was able to model the behaviour of the time series that represent the bandwidth occupation.
Kishimoto, Edilson Tsutomu. "Modelo de sistema de medição para melhoria contínua em sistema de gestão para laboratório de ensaios de equipamentos médicos". Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/3/3142/tde-08072011-163022/.
Texto completoThe main purpose of this work was the determination, implementation and evaluation of an optimized model of Measurement System for continuous improvement of a Management System for Testing Laboratory of medical equipment. The proposed model was developed from a survey of all possible indicators contained in the requirements of Standard ABNT NBR ISO/IEC 17025, also determining guidelines for interpretation of the requirements for continuous improvement of the management system and selecting the most important indicators from the customer\'s choice obtained from the analysis of critical incidents given by them. The model was validated in a Testing Laboratory of medical equipment accredited by INMETRO and is composed of indicators that meet the requirements of Standard ABNT NBR ISO / IEC 17025, selected according to the analysis of processes of the Testing Laboratory and aligned with the customers needs. These elements should help the managers of a Testing Laboratory of medical equipment to make strategic planning to improve performance in all activities, adopting and meeting the requirements of Standard ABNT NBR ISO/IEC 17025 which is one of the main contribution of this proposed work, as all Testing Laboratories are only concerned to meet the requirements of Standard ISO/IEC 17025 and only the text of this standard does not allow a clear definition of how to improve continuous process and the determination of additional guidelines, similar to what the standard ISO 9004 makes with the requirements of standard ISO 9001, will help the implementation of a Measurement System. The adoption of a Measurement System can allow Laboratories to gain greater control of their processes.
Lauer, Peter. "Advanced Proportional Servo Valve Control with Customized Control Code using White Space". Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-199441.
Texto completoRetonda-Modiya, John-Charly. "Development of an embedded system actuator node for intergration into an IEC 61850 based substation automation application". Thesis, Cape Peninsula University of Technology, 2012. http://hdl.handle.net/20.500.11838/1162.
Texto completoThe introduction of the IEC 61850 standard in substations for communication networks and systems by the International Electrotechnical Commission (IEC) in 2003 provided the possibility for communication between devices of different manufacturers. However, the advent of this standard also brought about many challenges associated with it. The challenges introduced by this fairly recent standard of communications in Substation Automation Systems (SAS), and the need for the development of cost effective IEC 61850- compliant devices, motivated the decision of the Centre for Substation and Energy Management Systems within the Electrical Engineering Department of the Cape Peninsula University of Technology to focus on the implementation of the IEC 61850 standard using an embedded hardware platform. The development of an IEC 61850 embedded application requires substantial knowledge in multiple domains such as data networking, software modelling and development of Intelligent Electronic Devices (IEDs), protection of the electrical system, system simulation and testing methods, etc. Currently knowledge about the implementation of the IEC 61850 standard usually resides with vendors and is not in the public domain. The IEC 61850 standard allows for two groups of communication services between entities within the substation automation system. One group utilizes a client-server model accommodating services such as Reporting and Remote Switching. The second group utilizes a peer-to-peer model for Generic Substation Event (GSE) services associated with time-critical activities such as fast and reliable communication between Intelligent Electronic Devices (IEDs) used for protection of the power network. The messages associated with the GSE services are the Generic Object Oriented Substation Event (GOOSE) messages. The use of GOOSE messages for protection of the electrical system is very important in modern substations. Detailed knowledge of the structure of these messages is important in instances requiring fault diagnosis to determine the cause of mal– operation or to address interoperability concerns or when developing custom IEC 61850- compliant devices with limited functionality. A practical protection application (overcurrent) case study is presented where GOOSE messages are exchanged between a commercial IED and an IEC 61850-compliant controller based on an embedded platform. The basic data model and software development of an actuator node for a circuit breaker is proposed using an IEC 61850 communication stack on an embedded platform. The performance of the GOOSE messages is confirmed to be as per the functional behaviour specified, and per the IEC 68150 standard in terms of the temporal behaviour required. This thesis document tables the methods, software programs, hardware interfacing and system integration techniques that allow for the development and implementation of a low cost IEC 61850-compliant controller unit on an embedded systems platform for the substation automation system. The overcurrent case study distributed between a commercial IED (SIEMENS Siprotec device) and the actuator application developed on an embedded platform for this project (DK60 board) is in compliance with the IEC 61850 standard and utilizing GOOSE messaging is successfully completed both in terms of functional and temporal behaviour. This novel research work contributes not only to the academic community, but to the international Power Systems community as a whole. Keywords: IEC 61850 standard, IEDs, GOOSE message, software modelling, software development, substation automation systems, communication stack, embedded systems, actuator.
Rosario, Jeferson Cardoso do. "Desenvolvimento de cateter implantável de monitorização de pressão intracraniana". Universidade do Vale do Rio dos Sinos, 2019. http://www.repositorio.jesuita.org.br/handle/UNISINOS/7702.
Texto completoMade available in DSpace on 2019-03-25T11:56:58Z (GMT). No. of bitstreams: 1 Jeferson Cardoso do Rosario_.pdf: 3523684 bytes, checksum: 6d033c623e7ef74a93692efd6ca37e8e (MD5) Previous issue date: 2019-01-18
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O traumatismo cranioencefálico (TCE) é atualmente a terceira maior causa de óbitos no âmbito mundial. Estudos recentes têm demonstrado que a monitorização de pressão intracraniana (PIC), como forma de cálculo da pressão de perfusão cerebral (PPC) é uma ferramenta importante para avaliação do fluxo sanguíneo cerebral (FSC), provocando sensível redução nas taxas de mortalidade. Além do TCE, outras patologias ou situações neurocirúrgicas tem utilizado a técnica de monitorização de PIC. A monitorização desse parâmetro foi proposta já na década de 50, onde um tubo com fluido em contato com o líquido cefalorraquidiano (LCR) era introduzido no espaço intracraniano e conectado a um transdutor de pressão externo. Com a evolução da indústria microeletrônica e dos sistemas microeletromecânicos, foi possível colocar os transdutores na ponta do cateter, permitindo uma monitorização menos invasiva, com menos riscos de infecções. Os cateteres atuais com micro transdutor na ponta podem ser divididos em três grupo: straingauge, fibra óptica e pneumático. Cada grupo possui suas características, entretanto o primeiro tem se demonstrado como solução mais robusta e confiável, com boa relação custo benefício. No presente trabalho foi proposto o desenvolvimento de um cateter implantável de monitorização de pressão intracraniana do tipo micro transdutor strain-gauge. Foram construídos protótipos funcionais e submetidos a ensaios de desempenho, especificados em norma técnica para monitorização de pressão sanguínea, a influência da temperatura na medição de pressão, bem como a exatidão das medições. Os processos empregados no trabalho são utilizados comumente na indústria de encapsulamento de semicondutores, porém foram levadas em consideração as especificidades da aplicação, adequando as técnicas disponíveis às geometrias e materiais empregados, considerando a necessidade de utilização de materiais biocompatíveis.
The traumatic brain injury (TBI) is nowadays the third cause of death in the world. Recent studies have shown the intracranial pressure (ICP) monitoring as an important tool for cerebral perfusion pressure (CPP) calculation and cerebral blood flow (CBF) assestment, reducing significantly the mortality statistics. Besides TBI, several others pathologies and neurosurgery conditions have been using the ICP monitoring technique. The proposal of ICP monitoring first appeared on the 50’s, where a tube fulfilled with fluid in contact with cerebrospinal fluid (CSF) was introduced into the intracranial space and connected to an external pressure transducer. With the waves of the microelectronics and microelectromechanical systems (MEMS) industry evolution, it was possible to put the transducer and all the electronics inside the catheter tip, allowing a less invasive monitoring, decreasing the risk of infection. The state of art catheters with micro transducer on the tip can be divided into three groups: strain-gauge, optical fiber and pneumatic. Each group has it’s own characteristics, however the first has been demonstrated as the rugged solution, being reliable, cost effective and with good accuracy. In the present work, it was proposed the development of an strain-gauge micro transducer implantable catheter for intracranial pressure monitoring. Functional prototypes were built and submitted to performance tests, according to the technical standards in the medical equipment area, the temperature influence over the pressure measurements was evaluated, as well as the accuracy. The adopted processes are commonly used in the semiconductor packaging industry, however it was considered the application special requirements, adapting the processes to the geometry and materials used, considering the needs of biocompatible materials.
Mikulášek, Michal. "Zařízení pro zaznamenávání proudové spotřeby LPWA senzorů". Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2020. http://www.nusl.cz/ntk/nusl-413004.
Texto completoTU, MING-KAI y 涂名凱. "Implement Novel Low Voltage Transfer Device Using Intelligent Electronic Devices and IEC 61850". Thesis, 2019. http://ndltd.ncl.edu.tw/handle/q44dkg.
Texto completo國立臺北科技大學
電機工程系
107
This thesis proposes an implementative novel Low Voltage Transfer Device (LVTD) using Intelligent Electronic Devices (IEDs) and IEC 61850.The analysis is done with IEC 61850 GOOSE communication statements that extractd from IED disturbance records and GOOSE monitoring tool after power failure simulation by IED test equipment, it was verified that LVTD functions can be implemented and meet interoperability requirement of IEC 61850 standard by configured architecture with IEDs. There are advantages as following: • The configured architecture is suitable for IEC 61850 substation application. • Investment cost lower than LVTD. • Easy for troubleshooting and maintenance, MTTR less than 15 minutes. • Integrated bus transfer and power system protection functions. • Issue alarm indications automatically during system operation.
Henry, Michael David. "ICP Etching of Silicon for Micro and Nanoscale Devices". Thesis, 2010. https://thesis.library.caltech.edu/5846/2/MDH-Thesis-Rev1.pdf.
Texto completoThe physical structuring of silicon is one of the cornerstones of modern microelectronics and integrated circuits. Typical structuring of silicon requires generating a plasma to chemically or physically etch silicon. Although many tools have been created to do this, the most finely honed tool is the Inductively Couple Plasma Reactive Ion Etcher. This tool has the ability to finesse structures from silicon unachievable on other machines. Extracting structures such as high aspect ratio silicon nanowires requires more than just this tool, however. It requires etch masks which can adequately protect the silicon without interacting with the etching plasma and highly tuned etch chemistry able to protect the silicon structures during the etching process.
In the work presented here, three highly tuned etches for silicon, and its oxide, will be described in detail. The etches presented utilize a type of etch chemistry which provides passivation while simultaneously etching, thus permitting silicon structures previously unattainable. To cover the range of applications, one etch is tuned for deep reactive ion etching of high aspect ratio micro-structures in silicon, while another is tuned for high aspect ratio nanoscale structures. The third etch described is tuned for creating structures in silicon dioxide. Following the description of these etches, two etch masks for silicon will be described. The first mask will detail a highly selective etch mask uniquely capable of protecting silicon for both etches described while being compatible with mainstream semiconductor fabrication facilities. This mask is aluminum oxide. The second mask detailed permits for a completely dry lithography on the micro and nanoscale, FIB implanted Ga etch masks. The third chapter will describe the fabrication and in situ electrical testing of silicon nanowires and nanopillars created using the methods previously described. A unique method for contacting these nanowires is also described which has enabled investigation into the world of nanoelectronics. The fourth and final chapter will detail the design and construction of high magnetic fields and integrated planar microcoils, work which was enabled by the etching detailed here. This research was directed towards creation of a portable NMR machine.
Tseng, Ying-Cheng y 曾英誠. "A Study of Synthesized Coplanar Waveguides using Integrated Passive Device (IPD) Technology and Circuit Applications". Thesis, 2012. http://ndltd.ncl.edu.tw/handle/73931360828356020324.
Texto completo國立臺灣科技大學
電機工程系
100
In this thesis, novel synthesized coplanar waveguides (CPWs) are developed using the glass substrate integrated passive device technology (GIPD). The proposed high-slow-wave-factor structures are capable of realizing synthesized transmission lines with a wide range of characteristic impedances and electrical lengths. The design concepts, equivalent circuit models, and experimental results are carefully investigated and discussed. By utilizing the synthesized CPWs, a miniaturized branch-line coupler is developed with a substantial size miniaturization of 91.5%. By incorporated with a novel 180?a phase inverter, a compact wideband rat-race coupler is also designed, showing improved bandwidths of 61% and 30%, respectively, as the sum and difference ports are excited. The size reduction ratio is remarkable, as well. Miniaturized stepped impedance resonators (SIRs), composed by three sections of synthesized CPWs, are realized and integrated to develop a novel miniaturized third-order bandpass filter with extended stopband rejection. The proposed bandpass filter has a very compact size, which is only 5% the size of a parallel-coupled SIR filter design. The first spurious passband is 4.3 times away from the fundamental one. The design concept, filter synthesis, and experimental results are discussed in detail. Finally, a compact 3-dB backward-wave coupled-line directional coupler is investigated. The even/odd-mode analysis and simulated and measured results are discussed. The coupling coefficients can be controlled by adjusting the parameters of the spiral inductors and MIM capacitors in the synthesized CPWs. The proposed coupler has an extremely compact size but comparable performances as well.
Liu, Yang. "Generic substation event monitoring based on IEC 61850 and IEEE 1588 standards". Thesis, 2015. http://hdl.handle.net/2440/97878.
Texto completoThesis (Ph.D.) -- University of Adelaide, School of Electrical and Electronic Engineering, 2015
Jiang, Shan. "Investigation of small signal dynamic performance of IPFC and UPFC devices embedded in AC networks". 2011. http://hdl.handle.net/1993/4388.
Texto completoKapuge, Kariyawasam Mudalige Sachintha Kariyawasam. "Implementation of an IEC 61850 Sampled Values Based Line Protection IED with a New Transients-Based Hybrid Protection Algorithm". 2016. http://hdl.handle.net/1993/31306.
Texto completoOctober 2016
Tsai, ShuiYi y 蔡淑儀. "Study of SiO2 thin films in MIS devices at extremely low temperature by ICP-CVD process". Thesis, 2006. http://ndltd.ncl.edu.tw/handle/42349509207766922759.
Texto completo國立成功大學
微機電系統工程研究所
94
Scaling down the electric device dimension is an inevitable tendency with each new generation in semiconductor industry. While the dimensions of devices continue to shrink, the thickness of the insulator layer is also reduced. The shrinkage of the oxide thickness increase direct tunneling through the gate dielectric and degrades the gate oxide reliability. For minimizing the gate leakage current, many new technologies are recommended to grow a high quality thin oxide film. The future trend has also turned it into focusing on the mobility and new applications, such as the substitutions of the glass substrates by flexible plastic substrates. Low temperature fabrication of high-quality gate oxide film is one of the key issues for further development of device. In this work, we report the formation of high-quality SiO2 thin films for the gate dielectric layer by using inductively coupled plasma chemical vapor deposition (ICP-CVD) technique from silane and oxygen gas mixtures at low temperatures. The influences of deposition parameters, including SiH4/O2 ratio、deposition pressure and ICP r.f power were studied. The electrical properties including leakage current density and breakdown voltage of the silicon dioxide are determined from current-voltage (I-V) characteristics of metal- insulator- semiconductor (MIS) devices. In this study, only the (111) diffraction peak is observed in 34.3 degree, while r.f power is above 1250 Watt. Analysis of the transmission electron microscopic (TEM) diffraction patterns indicates that the SiO2 films are single crystal with high quality. Analysis of the surface of SiO2 films by atomic force microscopy reveals a smooth surface with roughness in the 2.1~6.6 nm range. From the I-V curve it can be seen that the SiO2 thin film has a good electric property as prepared at 1750 Watt. The lowest leakage current of silicon dioxide films at the gate voltage of 1 V is about 8.2×10-8 A/cm2 and the breakdown field can be obtained is 15.8 MV/cm in this study. For improving its electrical characteristics, the post-annealing was proceeding in a conventional furnace tube at high temperatures varied from 300 ℃ to 700 ℃.High temperature annealing is known to increase the film crystallize atom, which can also decrease the defects in the SiO2 thin films. After annealing at 700 ℃, it can be found that the leakage current density is about 4.6×10-9 A/cm2 at the gate voltage of 1 V and the breakdown field is about 16.2 MV/cm
Chang, Kuo-Chin y 張國欽. "Study of Effects of Cu Stud Design and IMC Growth on the Reliability of Micro-Electronic Devices". Thesis, 2003. http://ndltd.ncl.edu.tw/handle/26869483800426382279.
Texto completo國立清華大學
動力機械工程學系
91
A wafer level package (WLP) without the underfill layer was introduced in recent years to address the demand of the electronic packaging industry for increased density and performance, as well as lightness, thinness, small size and cost-effectiveness. However, the solder joint reliability under thermal cycling conditions becomes a critical problem when mounting the WLP onto a PCB when the underfill layer has been eliminated. Consequently, enhancing the board level reliability is of primary concern in current WLP design. At the same time, the solder ball shear test has been widely adopted in the electronics industry to estimate the strength of solder ball attachment of advanced electronic packages. A solder ball with low shear strength is usually considered a weak solder joint in package reliability testing. Consequently, demands for increasing the solder ball shear strength have risen in recent years. In order to solve these problems, this research proposed a new WLP design, based on forming a Cu stud on the center of the surface of the solder pad. The solder pad with a round Cu stud was made using a semiconductor manufacturing process. Therefore, this novel Cu stud design technology is workable. To investigate the impact of a Cu stud on the solder ball shear strength and solder joint reliability, 3-D non-linear finite element models were used for the Cu stud design. In shear analysis, this investigation explored the effects of various parameters including the Cu stud’s dimension, shape, and material properties on the solder ball shear strength. Furthermore, the shear force-displacement curves, obtained by computational analysis, were compared with the experimental results to demonstrate the accuracy of the finite element models. In thermal cycling analysis, this research investigated the effects of various parameters, including the Cu stud’s dimension, shape, material properties and the die and PCB thicknesses on the solder joint’s reliability. To demonstrate the accuracy of the finite element models, the analytical results were compared with the experimental results and the experimental data reported in the literature. Comparing the experimental data with the results from the finite element analysis revealed that the finite element analysis was reliable. The analytical results established that a suitable size of Cu stud in a solder ball could effectively enhance the ball’s shear strength. Moreover, the solder joint reliability could be significantly improved by forming large Cu studs on the surfaces of the solder pads of WLP and PCB substrate, and could be further enhanced by combining large Cu studs with thin die. In addition, this research also explored the growth of intermetallic compounds (IMC) under aging for eutectic Sn-Pb solder reflowed on a Cu pad with an Au/Ni surface finish. The effects of the intermetallic layer on the solder ball shear strength were examined for various solder ball sizes, Cu pad sizes and Au layer thicknesses. The IMC growth is dominated by the diffusion-controlled mechanism, in which the vacancy diffusion is the main diffusion mode. The vacancies and atoms can interchange locations continuously. Experimental results indicated that the degradation of the solder ball shear strength was found to be mainly caused by brittle interfacial fracture, due to the formation and growth of the Au0.5Ni0.5Sn4 intermetallic layer. Decreasing the Au layer thickness can reduce the Au weight in the solder and the Au0.5Ni0.5Sn4 thickness, and so avoid the degradation of the solder ball shear strength. The findings of this research can offer designers and manufacturers an index to adjust the design for advanced ball grid array package to enhance their package reliability.
曾文玉. "Development of On-Line Photocatalyst-Assisted Digestion Device and PMMA Packed Column Coupled with ICP-MS for the Determination of Trace Metals in Freshwater". Thesis, 2009. http://ndltd.ncl.edu.tw/handle/03574998729090987686.
Texto completo吳俊甫. "Development of online HPLC-PMMA Chip-based Photo-Catalyst Reduction Device (PC2RD)-ICP-MS hyphenated system for determination of selenium species in nature water". Thesis, 2008. http://ndltd.ncl.edu.tw/handle/49617898272767421161.
Texto completo國立清華大學
生醫工程與環境科學系
96
Recently, speciation of selenium has attracted wide attention not only because the narrow threshold concentration range between deficiency and toxicity, but also its complexity in phisco-chemical form presenting in various environment and biological media. In general, the major soluble forms of selenium in nature waters have been proven to be selenite and selenate. The concentrations of selenium species in nature waters are extremely low; therefore, it is of great important to develop a sensitive and selective method for the study of the fate of selenium species in aqueous environment. According to literatures, undoubtedly, HPLC-ICP-MS hyphenated technique is one of the most sensitive method for the determination of trace selenium species. However, the analytical sensitivity of ICP-MS for selenium is highly limited by the high ionization energy (9.75 eV) of selenium and the inferior transport efficiency (mostly 2–3%) provided by traditional sample introduction systems. To compensate for the inferiority of HPLC-ICP-MS system, hydride generation (HG) technique has been successfully used to interface chromatography and spectrometers by enhancing analyte transportation efficiency and sensitivity. Recently, a novel photo-catalyst reduction device (PCRD) was developed, which has been verified as an efficient and high-performing technique for selenite and selenate detection. Because the PCRD was constructed by a PTFE tube, in this study, we intended to develop a PMMA (polymethylmethacrylate) Chip-base photo-catalyst reduction device (PC2RD) to improve the light transmission and sensitivity of detection. After the fabrication of meso-fluidic chip by CO2-Laser engraver, a UV lamp with 365 nm wavelength was used for the irradiation. Based on the experimental results, PC2RD system could improve the transport efficiency of analyte selenium species by 20%, comparing to PCRD system. Moreover, it merely needed 29s to transform inorganic selenium into gaseous selenide. The limit of detection of Se(Ⅳ) and Se(Ⅵ) were 4.9 and 3.9 ng/L, respectively. Based on the achieved analytical results, it indicated that our developed HPLC-PC2RD-ICP-MS system is a fast, simple and high sample transportation efficiency method, and has the ability to determine different selenium species in natural waters.
Wickremasuriya, Boosabaduge Achintha Hiruwan. "Development of a laboratory facility and experiments to support learning IEC 61850 based substation automation". 2016. http://hdl.handle.net/1993/30992.
Texto completoFebruary 2016
Lin, Cheng-Hsing y 林政興. "Development of Online HPLC-Chip-Based Immobilized Nano-TiO2 Photocatalytic Reduction Device-ICP-MS System for the Determination of Inorganic Selenium Species in Nature Water". Thesis, 2010. http://ndltd.ncl.edu.tw/handle/32186561502055038478.
Texto completo國立清華大學
生醫工程與環境科學系
98
Since it has been widely recognized that the toxicological behaviors and the biochemical functions of trace elements are highly dependent on chemical forms, to date, the information on selenium speciation has been considered indispensable for the risk assessment and better understanding of its biological behavior. Nowadays, the coupling of HPLC with different on-line detection systems by chemical hydride generation device has been proven very useful for the speciation of trace elements. However, in view of converting Se(VI) into gaseous hydride by traditional methods is limited by its high oxidation potential, a new on-line vapor generation technique permitting rapid and effective formation of hydride species from Se(VI) is still necessary for the construction of an adequate hyphenated system for the speciation of selenium species. Recently, an on-line HPLC-UV/nano-TiO2-ICP-MS system for the determination of inorganic selenium species was reported. Toward the goals of improvement of photocatalytical efficiency and reduction in sample consumption, we intended to develop a poly(methyl methacrylate) (PMMA) chip-based photo-reactor as an interfacing device resulting from the specific properties of microspace, and to combine HPLC and ICP-MS for the determination of Se(IV) and Se(VI) in aqueous samples. Meanwhile, to attain low per-unit manufacturing cost and rapid prototyping, a simple CO2 laser engraving technique was employed to fabricate the photo-reactor. Furthermore, to reduce the consumption of nano-TiO2 photocatalyst, we utilized a polyelectrolyte-poly(diallyldimethylammonium chloride) (PDADMAC) to assist the immobilization of nano-TiO2 particles onto the channel surface. Based on our experimental results, the device presented a greater stability in vaporization efficiency and lower baseline noise. Under the optimized condition, it merely needed 15s to transform inorganic selenium into gaseous selenide. The limit of detection of Se(IV) and Se(VI) were 0.043 and 0.042 μg L-1, respectively. For the analysis of irrigation water, the concentration of Se(IV) and Se(VI) were 0.109±0.019 and 0.090±0.013 μg L-1. Through a series of validation by analyzing 1643e Standard Reference Material and natural waters, it indicated that the proposed methods can be applied satisfactorily to the determination of inorganic selenium species in water samples. Based on the achieved analytical results, it also indicated that our developed on-line system is a fast, simple, low cost, low reagent consumption and high sample transportation efficiency method.
Wu, Chun-Wei y 吳俊緯. "From Disruptive Innovation and Hi-Tech Marketing Perspectives to Explore Personal Computers Innovation Model-Case Study of Advanced Micro Devices, Inc.(AMD)". Thesis, 2010. http://ndltd.ncl.edu.tw/handle/77275678468439535772.
Texto completo世新大學
國際經營管理碩士學位學程碩士班
98
Advanced Micro Devices has been competing with Intel in the over than thirty years through disruptive innovation technology. Currently, AMD is the onlyfirm who can provide complete solution of computer in this market through disruptive innovation, the “consumer-centric”,including microprocessor, chipset, and graphic in different computer platform. This research adopts“Qualitative Research”and“Case Study”to understand how AMD devotes its attention to develop its products through disruptive innovation in order to satisfy customer's demand by its low-cost, high stability, and high performance. AMD has presented their abilities of lead technology in different computer development periods. We could to perspective innovation model by “Disruptive Innovation”, “Open Innovation” and “Open Platform”of AMD in PC market. Therefore, we can duplicate this innovation model to create unique successful strategy. The Innovation comes from imitation. AMD once produced Intel-compatible product in early stage, and most products were reflection Intel’s specification in Epoch I/II. But “Imitation is more valuable than innovation”.Imitation is underappreciated. It can be more important to business growth than innovation could be. Imitation is not mindless repetition; it is an intelligent search for cause and effect. Therefore, AMD created successful produce,business model, and market strategy from their unique disruptive innovation technology in each Epoch.
Patchett, AL. "Toll-like receptors in the endangered Tasmanian devil and devil facial tumour disease". Thesis, 2018. https://eprints.utas.edu.au/28370/1/Patchett_whole_thesis_ex_pub_mat.pdf.
Texto completoChen, Yu y 陳煜. "Development of On-line HPLC-Chip-based Immobilized AuNPs/TiO2 Photo-catalytic Reduction Device-ICP-MS System for the Determination of Inorganic Arsenic Species in Natural Water". Thesis, 2012. http://ndltd.ncl.edu.tw/handle/72537267445270011867.
Texto completoHayes, DA. "Further immunohistochemical (IHC) characterisation of devil facial tumour disease 1 (DFT1) in the Tasmanian Devil (Sarcophilus harrisii)". Thesis, 2019. https://eprints.utas.edu.au/31712/1/Hayes_whole_thesis_ex_pub_mat.pdf.
Texto completoLuo, Yu-Ting y 羅鈺婷. "Development of a TiO2-coated microfluidic-based photocatalyst-assisted reduction device to couple HPLC with ICP-MS for the determination of mercury species in urine and water samples". Thesis, 2017. http://ndltd.ncl.edu.tw/handle/2mfr8y.
Texto completo國立清華大學
生醫工程與環境科學系
105
Mercury (Hg) is one of the most toxic elements impacting on human and ecosystem health. Each form of Hg possesses different physicochemical properties and toxicity profiles. In aquatic environments, the transformation of Hg species makes Hg more prone to biomagnification and bioaccumulation in food chains. In humans, food chain is the predominant route of exposure to Hg while urine is the excretory route. Thus, the concentration of Hg species in water and urine samples is conductive to assessing long-term body exposure. Nevertheless, the determination of Hg is still a challenge for analytical scientists due to the low-level of Hg and complex matrix in samples. To overcome these challenges, we developed a ultrasensitive and highly matrix tolerant microfluidic-based vapor generation (VG) system to couple with high-performance liquid chromatography (HPLC) separation and inductively coupled plasma-mass spectrometry (ICP-MS) detection for the determination of Hg species. The VG system exploited poly(methyl methacrylate) (PMMA) substrates of high optical quality to fabricate a microfluidic-based photocatalyst-assisted reduction device (microfluidic-based PCARD). Under the optimized conditions, the HPLC/TiO2-coated microfluidic-based PCARD/ICP-MS system enabled us to achieve detection limits of 1.39 and 2.95 ng L −1 for mercuric mercury (Hg2+) and methylmercury (MeHg+), respectively. Both Hg2+ and MeHg+ could be efficiently vaporized within 15 s, while a series of validation experiments indicated that our proposed method could be satisfactorily applied to the determination of Hg species in both human urine and environmental water samples.
Rajabi, Mina. "Flexible and Stretchable Biointerfacing for Healthcare Diagnostics". Licentiate thesis, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-245075.
Texto completoQC 20190306
Njova, Dion. "Evaluating of DNP3 protocol over serial eastern operating unit substations and improving SCADA performance". Diss., 2021. http://hdl.handle.net/10500/27683.
Texto completoSupervisory Control and Data Acquisition (SCADA) is a critical part of monitoring and controlling of the electrical substation. The aim of this dissertation is to investigate the performance of the Distributed Network Protocol Version 3.3 (DNP3) protocol and to compare its performance to that of International Electro-technical Commission (IEC) 61850 protocol in an electrical substation communication network environment. Building an electrical substation control room and installing the network equipment was going to be expensive and take a lot of time. The better option was to build a model of the electrical substation communication network and run simulations. Riverbend modeller academic edition known as Optimized Network Engineering Tool (OPNET) was chosen as a software package to model substation communication network, DNP3 protocol and IEC 61850 Protocol stack. Modelling the IEC 61850 protocol stack on OPNET involved building the used Open System Interconnection (OSI) layers of the IEC 61850 protocol stack onto the application definitions of OPNET. The Transmission Control Protocol/Internet Protocol (TCP/IP) configuration settings of DNP3 protocol were also modelled on the OPNET application definitions. The aim is to compare the two protocols and determine which protocol is the best performing one in terms of throughput, data delay and latency. The substation communication model consists of 10 ethernet nodes which simulate protection Intelligent Electronic Devices (IEDs), 13 ethernet switches, a server which simulates the substation Remote Terminal Unit (RTU) and the DNP3 Protocol over TCP/IP simulated on the model. DNP3 is a protocol that can be used in a power utility computer network to provide communication service for the grid components. DNP3 protocol is currently used at Eskom as the communication protocol because it is widely used by equipment vendors in the energy sector. DNP3 protocol will be modelled before being compared to the new recent robust protocol IEC 61850 in the same model and determine which protocol is the best for Eskom on the network of the power grid. The network load and packet delay parameters were sampled when 10%, 50%, 90% and 100% of devices are online. The IEC 61850 protocol model has three scenarios and they are normal operation of a Substation, maintenance in a Substation and Buszone operation at a Substation. In these scenarios packet end to end delay of Generic Object Oriented Substation Event (GOOSE), vi © University of South Africa 2020 Generic Substation Status Event (GSSE), Sampled Values (SV) and Manufacturing Messaging Specification (MMS) messages are monitored. The throughput from the IED under maintenance and the throughput at the Substation RTU end is monitored in the model. Analysis of the results of the DNP3 protocol simulation showed that with an increase in number of nodes there was an increase in packet delay as well as the network load. The load on the network should be taken into consideration when designing a substation communication network that requires a quick response such as a smart gird. GOOSE, GSSE, SV results on the IEC 61850 model met all the requirements of the IEC 61850 standard and the MMS did not meet all the requirements of the IEC standard. The design of the substation communication network using IEC 61850 will assist when trying to predict the behavior of the network with regards to this specific protocol during maintenance and when there are faults in the communication network or IED’s. After the simulation of the DNP3 protocol and the IEC 61850 the throughput of DNP3 protocol was determined to be in the range (20 – 450) kbps and the throughput of IEC61850 protocol was determined to be in the range (1.6 – 16) Mbps.
College of Engineering, Science and Technology
M. Tech. (Electrical Engineering)
Murenin, Constantine Aleksandrovich. "OpenBSD Hardware Sensors — Environmental Monitoring and Fan Control". Thesis, 2010. http://hdl.handle.net/10012/5234.
Texto completoSeyedi, Mirhojjat. "A Novel Intrabody Communication Transceiver for Biomedical Applications". Thesis, 2014. https://vuir.vu.edu.au/25847/.
Texto completoŠtípek, Radek. "Prvková analýza plochých zobrazovacích zařízení pro urban mining". Master's thesis, 2016. http://www.nusl.cz/ntk/nusl-351394.
Texto completoMeehan, Crystal Lea. "The role of early versus late gestational maternal immune activation in the aetiology of schizophrenia: establishing a rat model with a focus on cognitive symptomology and neuroinflammation". Thesis, 2018. http://hdl.handle.net/1959.13/1385728.
Texto completoSchizophrenia is a debilitating disorder of neurodevelopmental origins that likely stems from the cumulative action of a range of genetic and environmental factors. Epidemiological evidence has identified maternal infection during gestation as one significant environmental risk factor for the development of the disorder. Evidence from animal models has further validated the link between maternal immune activation (MIA) in the absence of an active infection and the later life development of schizophrenia-like pathology in the offspring. In particular, work in mouse models has suggested that the gestational time at which MIA occurs can alter the behavioural and neurobiological phenotype displayed. Specifically, that MIA in late gestation is involved in schizophrenia-relevant cognitive dysfunction and altered NMDA receptor expression, whereas MIA in early gestation is more closely associated with behavioural deficits reminiscent of positive symptomology and dopaminergic neurotransmission. The aim of the current thesis was to extend the mouse findings to another species, the rat, and further explore the effects of MIA. In addition to producing a reliable rat model of schizophrenia where distinct behavioural and neurological phenotypes associated with schizophrenia are produced following MIA at either early or late gestational time-points (gestational day 10 or 19, respectively), the current thesis extends on previous work by examining the schizophrenia biomarker of mismatch negativity and assessing the neuroinflammatory state of offspring. Behavioural assessments revealed that MIA in either early or late gestation produced transient impairments in working memory and reductions in PPI. In these behavioural studies, there was no clear distinction between a dopamine and glutamate-related behavioural phenotype based on the gestational timing of exposure. However, early but not late gestation MIA did produce alterations in the dopaminergic system of males, as indicated by increased dopamine 1 receptor mRNA in the nucleus accumbens. EEG experiments demonstrated that although the male rat brain is able to generate human-like (adaptation-independent) mismatch responses (MMRs), and although MIA (regardless of gestational timing) does alter MMRs, it does not do so in a manner comparable with schizophrenia. Immunohistochemical techniques revealed that MIA does result in subtle neuro-immune changes in adult offspring, with an increase in microglial immunoreactivity identified in the frontal white matter of late, but not early, gestation MIA animals. Furthermore, a strong trend towards increased astrocyte immunoreactivity that approached significance was identified in the prefrontal cortex of late, but not early MIA offspring. The combined results have demonstrated that MIA during the chosen gestational time-points are sufficient to disrupt neurodevelopmental processes producing long-term alterations in behavioural and neuropathological measures relevant to schizophrenia. However, the phenotype characterised here deviates slightly from previous findings from mouse models indicating potential differences in the critical periods of neurodevelopmental susceptibility to MIA exposure between the rat and mouse. Importantly this research has provided insights into the underlying neuro-immune changes which may contribute to the behavioural abnormalities seen in adult MIA offspring and has provided evidence that MIA in rats can alter the prominent schizophrenia relevant electrophysiological biomarker of adaptation-independent MMRs, providing a basis to further investigate these measures and their underlying mechanisms.