Tesis sobre el tema "Hydrogelator"
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St, Martin Michael J. "Synthesis and Characterization of Sugar Derivatives as Functional Gelators". ScholarWorks@UNO, 2012. http://scholarworks.uno.edu/td/1524.
Texto completoAwhida, Salmah. "Functionalised dipeptides as hydrogelators for energy transfer and as drug delivery vehicles". Thesis, University of Liverpool, 2015. http://livrepository.liverpool.ac.uk/2014048/.
Texto completoFleming, Scott. "Aromatic peptide amphiphiles : design rules for hydrogelaion and co-assembly". Thesis, University of Strathclyde, 2014. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=23213.
Texto completoFoster, Jamie S. "Relating the chemical reactivity of supramolecular hydrogelators and the physical properties of their gels". Thesis, Heriot-Watt University, 2017. http://hdl.handle.net/10399/3400.
Texto completoYücel, Tuna. "Early-time, beta-hairpin peptide self-assembly and hydrogelation structure, kinetics, and shear-recovery /". Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 136 p, 2009. http://proquest.umi.com/pqdweb?did=1654493371&sid=4&Fmt=2&clientId=8331&RQT=309&VName=PQD.
Texto completoBastrop, Martin Verfasser], Karsten [Akademischer Betreuer] [Mäder, Alfred [Akademischer Betreuer] Blume y Heike [Akademischer Betreuer] Bunjes. "Physico-chemical characterization of a novel class of bolaamphiphilic hydrogelators / Martin Bastrop. Betreuer: Karsten Mäder ; Alfred Blume ; Heike Bunjes". Halle, Saale : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2011. http://d-nb.info/1025135342/34.
Texto completoBouguéon, Guillaume. "Formulation de nanosystèmes biocompatibles pour l’ingénierie tissulaire par impression 3D (bioprinting)". Thesis, Bordeaux, 2020. http://www.theses.fr/2020BORD0006.
Texto completo3D bioprinting is an emerging field of tissue engineering, that aims at faithfully reproducing the complex microarchitecture of tissues and organs. Despite a wide range of biomaterials used in bioink formulation, it is essential to find an alternative to the natural and synthetic biomaterials conventionally used, mimicking extracellular matrix and presenting printing capabilities jointly.The present work demonstrated for the first time, the ability of the bioinspired nucleolipid molecule diC16dT to formulate an extrusion bioprinting ink. The ink formulated in cell culture medium showed rheological properties allowing its continuous printability. It was also possible to incorporate gingival fibroblasts while maintaining the cell viability within bioconstructions. This ink also offered several adaptation possibilities, especially in terms of diC16dT concentration and cell culture medium to meet other cellular types requirements. Finally, the preliminary work showed the feasibility of the incorporation of liposomes into the ink formulation without affecting its printing capabilities. Thus, it would possible to further consider the delivery of active substances or nutrients within the bioconstructions. This application has to the best of our knowledge not been developed yet for liposomes
Li, Jyun-Ting y 黎俊廷. "The Reversible pH-Stimulative Hydrogelators Based onGlycolipid without Possessing Conventional pH-ResponsiveMoieties". Thesis, 2015. http://ndltd.ncl.edu.tw/handle/5scdvf.
Texto completo中原大學
化學研究所
103
Two low molecular weight hydrogelators have been developed by us. These two hydrogelators are the glycolipids that consist of glucosamine, tethering the (2S,3S)-2,3-dihydroxydecanoyl acid and (2R,3R)-2,3- dihydroxy tetradecanoyl acid, respectively.(S10 and R14). Among these two compounds, S10 a reversible gelator exhibits the stimulus-responsive ability at pH 3.0-5.0. The asymmetric synthese of these two dihydroxyalkanoyl acids have been accomplished by using chiral-pool method strategy. Herein, D-ribose is used as the starting material to synthesize these two optically active dihydroxyalkanoyl acids that configurations are mirro image each other at the same time.
Nai-ShinFan y 范乃心. "Hydrogelation of Coil-Sheet Poly(L-Lysine)-block-Poly(L-Threonine) Block Copolypeptides". Thesis, 2017. http://ndltd.ncl.edu.tw/handle/94h6wz.
Texto completoXuan-YouShen y 沈烜右. "Hydrogelation of Star-shaped Poly(L-lysine) Polypeptides Modified with Different Functional Groups". Thesis, 2018. http://ndltd.ncl.edu.tw/handle/53373e.
Texto completoAndrade, Juliana J. "Self-assembled noncovalent hydrogels based on dehydrodipeptides". Master's thesis, 2012. http://hdl.handle.net/1822/23000.
Texto completoSelf-assembly of nanometric structures from molecular building blocks is an effective way to make new functional materials for biological and technological applications. In this work we synthesized new N-modified dehydrodipeptides based on phenylalanine and dehydroamino acid units attached to aromatic modifiers, namely trimesoyl, terephtaloyl, diphenylacetyl and 2,2´-(1,3-phenylene)diacetyl in a pattern that afforded mono or polysubstitued organic molecules. The potential use of these new compounds as hydrogelators was evaluated. The results showed that most of the prepared compounds behave as efficient molecular hydrogelators forming hydrogels at minimum gelation concentrations of 0.3-0.8 wt%. Two new compounds failed to form hydrogels probably due to unfavorable thermodynamic contribution of intermolecular interactions. The self-aggregation pattern of the hydrogelators was investigated by STEM microscopy technique, revealing different shapes depending on the N-aromatic moiety. A circular dichroism analysis was also performed in order to evaluate if the peptides aggregate into any characteristic secondary structure, usually found in protein folding. We found that the 5 hydrogelators had characteristic signals, demonstrating the presence of organized structures even below the minimum gelation concentration. At elevated pH or for the non-hydrogelating compounds, it was not observed signals indicative of the presence of such structures.
A automontagem de estruturas manométricas, a partir de entes de dimensão molecular, consiste em uma alternativa eficiente para a síntese de novos materiais funcionais para aplicações biotecnológicas. Neste trabalho, foram sintetizados novos desidrodipéptidos modificados em sua porção N-terminal. Os dipéptidos continham fenilalanina e desidroaminoácidos e os grupos modificadores foram grupos aromáticos (trimesoil, tereftaloil, difenilacetil e o 2,2´-(1,3- phenileno)diacetil) os quais foram conjugados de forma a gerar compostos mono ou polissubstituídos. A capacidade de gelificar em meio aquoso, destes novos compostos, foi avaliada e os resultados mostraram que a maioria deles conseguiram gelificar em meio aquoso em concentrações mínimas na faixa 0.3-0.8 m%. Dois destes compostos não conseguiram originar hidrogéis, provavelmente devido a um balanço termodinamicamente desfavorável das interacções intermoleculares entre os constituintes do sistema. O padrão morfológico resultante da auto-agregação dos compostos que geraram os hidrogéis foi investigado pela técnica de microscopia electrónica de transmissão por scaneamento (STEM). Esta análise revelou que houve a ocorrência de diferentes tipos de estruturas nos hidrogéis, dependendo de qual modificador aromático foi utilizado. Também realizou-se uma análise de Dicroísmo Circular para avaliar se os péptidos agregavam-se em algum padrão de estrutura secundária característica de enovelamento proteico. Detectou-se que nos 5 agentes gelificates haviam sinais característicos da presença de estruturas organizadas mesmo abaixo da concentração de gelificação mínima. Em pH elevado e nas moléculas não gelificantes, não se observam sinais indicativos da presença deste tipo de estruturas.
Fundação para a Ciência e a Tecnologia (FCT)
Maity, Mitasree. "Bile Acid based Supramolecular Gels, Soft Hybrid Materials and their Applications". Thesis, 2016. http://etd.iisc.ac.in/handle/2005/2928.
Texto completoMaity, Mitasree. "Bile Acid based Supramolecular Gels, Soft Hybrid Materials and their Applications". Thesis, 2016. http://hdl.handle.net/2005/2928.
Texto completoChakrabarty, Arkajyoti. "Bile Acid Based Supramolecular Gels, Semiconductor Nanocrystals And Soft Hybrid Materials". Thesis, 2012. https://etd.iisc.ac.in/handle/2005/2513.
Texto completoChakrabarty, Arkajyoti. "Bile Acid Based Supramolecular Gels, Semiconductor Nanocrystals And Soft Hybrid Materials". Thesis, 2012. http://etd.iisc.ernet.in/handle/2005/2513.
Texto completoLai, Yeu-Ching y 賴雨青. "The Reversible pH-Responsive, and Water-Erosive Low-Molecular-Weight Hydrogelators Based on Glycolipids with Homochiral α,β-Dihydroxyfatty Acid Moiety andits Application to Drug Release in vitro". Thesis, 2013. http://ndltd.ncl.edu.tw/handle/29313676157819180815.
Texto completo中原大學
化學研究所
101
The primary concern of this study is to explore the research on a series of glycolipids with homochiral α,β-dihydroxyfatty acid moiety of low-molecular-mass gelators (GR-1~GR-4) and apply to drug delivery system. In gelation test, the gelators GR-1 was developed a stable gel form in purified water, in which the minimal concentration of gelation was 4 mg/mL and the temperature (Tgel) of gel-solution transition was at 64 oC. The self-assembly of intermolecular hydrogen bonding gelator GR-1 was confirmed by 1H NMR spectra. The bilayer-packed lamellar structure within ribbon-like fibers was resulted in the self-assembly of GR-1 by entanglement to produce 3-D network structures. In the pH-stimuli responsive test, the hydrogel generated from gelators GR-1 was proving responsive to the change of pH value, and gel was formed only at pH 7.0, 8.0, 9.0. It was identified that the respondence between the gelator and the pH-stimuli was provided with the reversible feature. In the investigation of drug delivery in vitro, the hydrogel was generated from gelators GR-1 regarded as the carrier. A model drug 5-fluorouracil (5-FU) was entrapped in supramolecular hydrogels.. The influence of the concentration of hydrogelator, concentration of 5-FU and pH values of phosphate buffer saline was investigated by high performance liquid chromatography (HPLC) on the releasing behavior of 5-FU. The study of the releasing kinetics was indicated that the releasing behavior of 5-FU was in accord with the Non- Fickian model by the Peppas equation .
Banerjee, Supratim. "Studies On Low Molecular Mass Gelators". Thesis, 2005. https://etd.iisc.ac.in/handle/2005/1551.
Texto completoBanerjee, Supratim. "Studies On Low Molecular Mass Gelators". Thesis, 2005. http://etd.iisc.ernet.in/handle/2005/1551.
Texto completoSrivastava, Aasheesh. "Molecular Modulation Of Material Properties: Studies On Nanoparticles, Nanoassemblies, And Low Molecular-Mass Gelator". Thesis, 2006. https://etd.iisc.ac.in/handle/2005/327.
Texto completoSrivastava, Aasheesh. "Molecular Modulation Of Material Properties: Studies On Nanoparticles, Nanoassemblies, And Low Molecular-Mass Gelator". Thesis, 2006. http://hdl.handle.net/2005/327.
Texto completoBiswakarma, Dipen. "Development of Stimuli-Responsive Self-Assembled Materials for Biomolecular Applications". Thesis, 2019. https://etd.iisc.ac.in/handle/2005/4567.
Texto completoBhat, Shreedhar. "Soft Materials Derived From Bile Acid Analogues". Thesis, 2007. https://etd.iisc.ac.in/handle/2005/483.
Texto completoBhat, Shreedhar. "Soft Materials Derived From Bile Acid Analogues". Thesis, 2007. http://hdl.handle.net/2005/483.
Texto completoBhattacharjee, Subham. "Design, Synthesis and Applications of Novel Two-Component Gels and Soft-Nanocomposites". Thesis, 2014. http://etd.iisc.ac.in/handle/2005/2981.
Texto completoBhattacharjee, Subham. "Design, Synthesis and Applications of Novel Two-Component Gels and Soft-Nanocomposites". Thesis, 2014. http://etd.iisc.ernet.in/handle/2005/2981.
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