Siga este enlace para ver otros tipos de publicaciones sobre el tema: Hereditary behaviour.

Artículos de revistas sobre el tema "Hereditary behaviour"

Crea una cita precisa en los estilos APA, MLA, Chicago, Harvard y otros

Elija tipo de fuente:

Consulte los 50 mejores artículos de revistas para su investigación sobre el tema "Hereditary behaviour".

Junto a cada fuente en la lista de referencias hay un botón "Agregar a la bibliografía". Pulsa este botón, y generaremos automáticamente la referencia bibliográfica para la obra elegida en el estilo de cita que necesites: APA, MLA, Harvard, Vancouver, Chicago, etc.

También puede descargar el texto completo de la publicación académica en formato pdf y leer en línea su resumen siempre que esté disponible en los metadatos.

Explore artículos de revistas sobre una amplia variedad de disciplinas y organice su bibliografía correctamente.

1

Schwarzer, Gudrun, Susanne Huber, Martina Grüter, Thomas Grüter, Cornelia Groß, Melanie Hipfel y Ingo Kennerknecht. "Gaze behaviour in hereditary prosopagnosia". Psychological Research 71, n.º 5 (10 de junio de 2006): 583–90. http://dx.doi.org/10.1007/s00426-006-0068-0.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
2

Usmonov, Botir. "A Numerical Solution of Hereditary Equations with a Weakly Singular Kernel for Vibration Analysis of Viscoelastic Systems / Vienâdojumu Ar Vâjo Singulâro Kodolu Skaitliskais Risinâjums Iedzimto Viskoelastîgo Sistçmu Vibrâciju Analîzei". Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences. 69, n.º 6 (1 de diciembre de 2015): 326–30. http://dx.doi.org/10.1515/prolas-2015-0048.

Texto completo
Resumen
Abstract Viscoelastic, or composite materials that are hereditary deformable, have been characterised by exponential and weakly singular kernels in a hereditary equation. An exponential kernel is easy to be numerically implemented, but does not well describe complex vibratory behaviour of a hereditary deformable system. On the other hand, a weakly singular kernel is known to describe the complex vibratory behaviour, but is nontrivial to be numerically implemented. This study presents a numerical formulation for solving a hereditary equation with a weakly singular kernel. Recursive algebraic equations, which are numerically solvable, are formulated by using the Galerkin method enhanced by a numerical integration and elimination of weak singularity. Numerical experiments showed that the present approach with a weakly singular kernel is well fitted into a realistic vibratory behaviour of a hereditary deformable system under dynamic loads, as compared to the same approach with an exponential kernel.
Los estilos APA, Harvard, Vancouver, ISO, etc.
3

Di Paola, Mario y Michele Fabio Granata. "Fractional model of concrete hereditary viscoelastic behaviour". Archive of Applied Mechanics 87, n.º 2 (18 de noviembre de 2016): 335–48. http://dx.doi.org/10.1007/s00419-016-1196-7.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
4

Levina, Anna S., Nina A. Bondarenko, Natalia V. Shiryaeva, Alexander I. Vaido y Natalia A. Dyuzhikova. "Hereditary determined diving behaviour in rats as a factor of fitness". Ecological genetics 18, n.º 3 (9 de octubre de 2020): 317–28. http://dx.doi.org/10.17816/ecogen25817.

Texto completo
Resumen
Background. Rats natural ability to swim and dive provides adaptation in the wildlife and is widely applied as an instrument in experimental physiology. Nevertheless theres little scientific evidence on diving behaviour in rats itself. Meanwhile this behavioural pattern might be a notable trait to shed light on functional features of the nervous system, the higher nervous activity structure and evolutional adaptability in animals, including inherited ones. Materials and methods. In the present work we compared the performance of the spontaneous diving behaviour in the Morris water maze and forced diving behaviour in the Extrapolation escape task in two selected rat strains genetically differing in the nervous system excitability threshold. Results. We found a greater extent and adaptive pattern of both types of the diving behaviour in the high-excitable LT strain. This may be due to such basic features of this strain as high exploratory activity and an increased level of fear reactions. It was also shown that the second, low-excitable HT rat strain, demonstrates maladaptive jumping behaviour in the Extrapolation escape task due to higher anxiety level in the stress conditions. Conclusion. Observed differences between two strains allow us to consider the diving behaviour performed by high-excitable rats an inherited strain characteristic resembling adaptive rat behaviours in the wild and look forward to investigate its genetic mechanisms.
Los estilos APA, Harvard, Vancouver, ISO, etc.
5

Ermakov, Pavel. "Hemispheric asymmetry of aggressive behaviour and hereditary factors". International Journal of Psychophysiology 94, n.º 2 (noviembre de 2014): 143. http://dx.doi.org/10.1016/j.ijpsycho.2014.08.654.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
6

Iglauer, F., C. Beig, J. Dimigen, S. Gerold, A. Gocht, A. Seeburg, S. Steier y F. Willmann. "Hereditary compulsive self-mutilating behaviour in laboratory rabbits". Laboratory Animals 29, n.º 4 (1 de octubre de 1995): 385–93. http://dx.doi.org/10.1258/002367795780740140.

Texto completo
Resumen
During the last few years an increasing number of cases of extensive automutilation has been observed in a rabbit breeding colony of Checkered crosses. Digits and pads of the front feet were traumatized. No other behavioural abnormalities or signs of disease were evident. Self-mutilation was seen both in stock, breeding and experimental animals, in rabbits kept singly in cages and in those housed in groups on the ground, in rabbits kept in different buildings and under the care of different staff members. This behavioural abnormality of Checkered crosses has also been observed in animals after being placed into other institutions or private homes. No evidence of an agent responsible for the occurrence of self-injury could be found with parasitological, mycological, histological, clinical or haematological examination. Twelve to 16 animals are affected yearly in a colony varying in size between 130 and 230 rabbits. Following complete healing, relapses occurred up to 3 times per year, on either the same or the opposite front foot. In the last 21 cases episodes of automutilation could be regularly interrupted with the dopamine antagonist, haloperidol. Similar signs of automutilation were never seen in animals of another breeding line kept in the same building and under the same conditions nor in animals brought in from other breeding colonies. A relatively high coefficient of inbreeding can be presupposed in this 15-year-old breeding colony of Checkered crosses. A genetic predisposition for the behavioural anomaly described appears very likely.
Los estilos APA, Harvard, Vancouver, ISO, etc.
7

Tchuraev, Rustem N. "Epigenes — overgenes level hereditary units". Ecological genetics 8, n.º 4 (15 de diciembre de 2010): 17–24. http://dx.doi.org/10.17816/ecogen8417-24.

Texto completo
Resumen
The theoretical and experimental aspects concept of epigenes are considered. In epigenes part of the heritable information is preserved, coded and trasmitted in generations out of the primary structure of genomic DNA. The behaviour under crosses simples modelic epigenes is demonstrated. The variants of molecular-genetics mechanisms of epigenes and original results of experimental construction artificials epigenes by methods gene-engenering are presented. The ontogenetic and phylogenetic roles of epigene systems are discussed. It has been shown, that even simplest epigene systems can provide key events of ontogeny. The epigenes systems can provide non-Darwinian evolutionary strategy by means of “remember” relatively unsuccesful muves of evolution and preservation reserved variants of ontogeny.
Los estilos APA, Harvard, Vancouver, ISO, etc.
8

PALKA, P. "Biventricular diastolic behaviour in patients with hypertrophic and hereditary hemochromatosis cardiomyopathies". European Journal of Echocardiography 5, n.º 5 (octubre de 2004): 356–66. http://dx.doi.org/10.1016/j.euje.2004.01.003.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
9

Pridmore, Saxby, Gyaneshwar Rao y Prosper Abusah. "Hereditary Spastic Paraplegia with Dementia". Australian & New Zealand Journal of Psychiatry 29, n.º 4 (diciembre de 1995): 678–82. http://dx.doi.org/10.3109/00048679509064985.

Texto completo
Resumen
Objective: Hereditary spastic paraplegia (HSP) with dementia is a very rare condition. The aim of the paper is to present the first report of HSP in a Fijian Indian family. Method: A psychiatrist and a general physician examined the affected members of the family on five occasions over three years. Results: There are three affected individuals In a sibship of seven. The parents are without symptoms and the marriage is non-consanguineous. The course of the disease has been remarkably similar. All subjects were healthy and performing well in the early years of school. In two, symptoms of cognitive loss preceded difficulty with ambulation and in the third, these symptoms appeared concurrently. All subjects had both symptoms by 13 years of age; they were unable to ambulate independently by the mid to late teens, at which time there was dysarthria spastic paraplegia and dementia. One subject suffered a three month episode of hypomanic behaviour. Over the three-year study period deterioration was slight but noticeable. Conclusions: It is possible that HSP is more commonly associated with pre-senile dementia than is currently recognised. HSP with dementia is a very rare cause of failing school performance. Physical examination of the patient and other family members is indicated if this diagnosis is being considered.
Los estilos APA, Harvard, Vancouver, ISO, etc.
10

KALBE, M., B. HABERL, J. HERTEL y W. HAAS. "Heredity of specific host-finding behaviour in Schistosoma mansoni miracidia". Parasitology 128, n.º 6 (13 de mayo de 2004): 635–43. http://dx.doi.org/10.1017/s0031182004005037.

Texto completo
Resumen
Two strains of Schistosoma mansoni were used to investigate the hereditary basis of species-specific host recognition by analysing behavioural responses of miracidia to snail-conditioned water. An Egyptian strain of S. mansoni, capable of distinguishing its host snail Biomphalaria alexandrina from other snails was cycled repeatedly through Biomphalaria glabrata, the intermediate host of a Brazilian strain known to respond even to non-susceptible snails with high intensity. After 5 cycles in the non-natural host, miracidia of the Egyptian strain still retained their preference for the original host snail. In a second experiment, host-finding behaviour of hybrids between these two parasite strains was studied. In the F1 generation, hybrids of both parental combinations showed the same low degree of specificity as the pure-bred Brazilian strain. Approximately one quarter of F2 hybrids proved to be as discriminatory as the Egyptian strain, confirming dominant Mendelian inheritance of non-specificity in schistosome miracidial host-finding behaviour. Moreover, hybrids seem to have lost the ability to develop in B. alexandrina, possibly suggesting a link between host recognition and host compatibility. The heredity of this behavioural trait is of evolutionary and epidemiological significance, since a shift to low host-finding specificity might have been a prerequisite for S. mansoni to acquire new host snails after being introduced to South America by the slave trade.
Los estilos APA, Harvard, Vancouver, ISO, etc.
11

Caraballo, Tomás, María J. Garrido-Atienza y José Real. "The Exponential Behaviour of Nonlinear Stochastic Functional Equations of Second Order in Time". Stochastics and Dynamics 03, n.º 02 (junio de 2003): 169–86. http://dx.doi.org/10.1142/s0219493703000735.

Texto completo
Resumen
Sufficient conditions for exponential mean square stability of solutions to delayed stochastic partial differential equations of second order in time are established. As a consequence of these results, some on the pathwise exponential stability of the system are proved. The stability results derived are applied also to partial differential equations without hereditary characteristics. The results are illustrated with several examples.
Los estilos APA, Harvard, Vancouver, ISO, etc.
12

Allen, Melinda S. "Oscillating climate and socio-political process: the case of the Marquesan Chiefdom, Polynesia". Antiquity 84, n.º 323 (1 de marzo de 2010): 86–102. http://dx.doi.org/10.1017/s0003598x00099786.

Texto completo
Resumen
Does climate affect behaviour and social process? In this case study, powerful scientific, anthropological and archaeological arguments are deployed to show that it can. The capricious climate of the latest centuries of the Marquesas Islands was instrumental in transforming a chieftain society into less hereditary and more flexible polities by the time of European contact.
Los estilos APA, Harvard, Vancouver, ISO, etc.
13

Bologna, E. y M. Zingales. "Stability analysis of Beck's column over a fractional-order hereditary foundation". Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences 474, n.º 2218 (octubre de 2018): 20180315. http://dx.doi.org/10.1098/rspa.2018.0315.

Texto completo
Resumen
This paper considers the case of Beck's column resting on a hereditary bed of independent springpots. The springpot possesses an intermediate rheological behaviour among linear spring and linear dashpot. It is defined by means of couple ( C β , β ) that characterize the material of the element and is ruled by a Caputo's fractional derivative. In this paper, we investigate the critical load of the column under the action of a follower load by means of a novel complex transform that allows to use the Routh–Hurwitz theorem in the complex half-plane for the stability analysis.
Los estilos APA, Harvard, Vancouver, ISO, etc.
14

Caraballo, Tomás, Antonio M. Márquez-Durán y Rivero Felipe. "Asymptotic behaviour of a non-classical and non-autonomous diffusion equation containing some hereditary characteristic". Discrete & Continuous Dynamical Systems - B 22, n.º 5 (2017): 1817–33. http://dx.doi.org/10.3934/dcdsb.2017108.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
15

Haggie, J. A., A. Howell, R. A. Sellwood, J. M. Birch y S. L. Schor. "FIBROBLASTS FROM RELATIVES OF PATIENTS WITH HEREDITARY BREAST CANCER SHOW FETAL-LIKE BEHAVIOUR IN VITRO". Lancet 329, n.º 8548 (junio de 1987): 1455–57. http://dx.doi.org/10.1016/s0140-6736(87)92206-9.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
16

Dongre, Nikhil, Varsha Ambwani, Vinita Elizabeth Mani y Vimal Kumar Paliwal. "Alien-hand syndrome with mirror movements in hereditary diffuse leukoencephalopathy with spheroids". Practical Neurology 22, n.º 4 (24 de marzo de 2022): 321–23. http://dx.doi.org/10.1136/practneurol-2021-003237.

Texto completo
Resumen
Hereditary diffuse leukoencephalopathy with spheroids is a rare genetic disorder caused by mutations of the colony-stimulating factor 1 receptor gene. It is an adult-onset leukodystrophy, with a wide spectrum of neurological and psychiatric manifestations that includes Parkinsonism, dementia, seizures, limb weakness, spasticity and abnormal motor behaviour. Alien-hand syndrome and mirror movements are rare manifestations of this and other neurodegenerative disorders. We describe a woman with progressive limb and trunk rigidity, Parkinsonism and dementia, who also had involuntary left arm levitation (part of the posterior variant of alien-hand syndrome) and left-hand mirror movements. We discuss the different types of alien-hand syndrome, and the likely mechanisms of arm levitation and mirror movements.
Los estilos APA, Harvard, Vancouver, ISO, etc.
17

Nikolov, S. y D. Kanakov. "Influencing factors leading to damaging behavior - feather pecking and cannibalism in game birds". Trakia Journal of Sciences 18, n.º 4 (2020): 377–87. http://dx.doi.org/10.15547/tjs.2020.04.012.

Texto completo
Resumen
Behavioural disorders, including feather pecking and cannibalism, are a common problem in both domestic and wild birds. Damaging behaviour is polyethiological and is divided into two major groups of factors: extrinsic and intrinsic. Extrinsic factors are those that are not dependent on the species of bird-factors from outside the organism which causes injurious pecking (IP). There are three abiotic groups assigned: nutritional factors (the composition of the ration and nutritional strategies), factors of the environment (light, temperature, sound, and air), and conditions of breeding (density, size, type of system, and enrichment of the conditions of breeding). Intrinsic are the factors that depend on the species of bird – factors coming from the organism and influencing injurious pecking. Seven biotic factors are assigned: social (imitating, sexual, stereotypical and maternal behaviour), sex (male and female sex hormones), age (young and adult), stress (fear, stress and corticosterone), central-nervous (serotonin, dopamine and noradrenaline), hereditary (genotypic and phenotypic manifestation) and immunological. It is important to have an understanding of the influencing factors leading to an onset of injurious pecking in order to successfully control the behavior in game birds bred in captivity.
Los estilos APA, Harvard, Vancouver, ISO, etc.
18

Sisek-Šprem, M., M. Herceg y V. Jukić. "Does family history of schizophrenia affect the severity of disease?" European Psychiatry 33, S1 (marzo de 2016): S107. http://dx.doi.org/10.1016/j.eurpsy.2016.01.095.

Texto completo
Resumen
IntroductionPrevious studies have demonstrated that family history is associated with earlier age at onset, severity of positive and negative symptoms, and the duration of untreated illness. Hereditary factors may contribute a vulnerability for antisocial and/or violent behaviour per se, and for other stable characteristics such as aggressive behaviour.AimTo analyze the impact of family history of schizophrenia and aggressive behavior among members of family on severity of disease and aggressive behavior of patients.MethodThe study population consisted of 120 male schizophrenic patients classified into non-aggressive (n = 60) and aggressive (n = 60) groups, based on indication for admission in hospital (aggression/anything else but aggression). For severity of disease, we assessed psychopathology using the Positive and Negative Syndrome Scale (PANSS), the number of hospitalizations and the total equivalent dose of therapy (collected from medical record). The presence of a family history and aggression in family was assessed using a semi-structured interview of patients and, when available, family members.ResultsTwenty-seven (22.5%) participants were determined to have at least one family member with schizophrenia or another psychotic disorder, with no difference between aggressive (10%) and non-aggressive (12.5%) group. There was no significant interaction between family history and severity of disease (PANSS, number of hospitalizations, total equivalent dose of therapy). Aggressive behaviour in first-degree family member had no influence on aggressive behaviour of patients with schizophrenia.ConclusionFamily history of schizophrenia does not affect the severity of disease nor aggressive behaviour.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Los estilos APA, Harvard, Vancouver, ISO, etc.
19

Gietel-Habets, J. J. G., C. E. M. de Die-Smulders, V. C. G. Tjan-Heijnen, I. A. P. Derks-Smeets, R. van Golde, E. Gomez-Garcia y L. A. D. M. van Osch. "Professionals' knowledge, attitude and referral behaviour of preimplantation genetic diagnosis for hereditary breast and ovarian cancer". Reproductive BioMedicine Online 36, n.º 2 (febrero de 2018): 137–44. http://dx.doi.org/10.1016/j.rbmo.2017.11.005.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
20

Comings, D. E. y B. G. Comings. "Hereditary Agoraphobia and Obsessive-Compulsive Behaviour in Relatives of Patients with Gilles de la Tourette's Syndrome". British Journal of Psychiatry 151, n.º 2 (agosto de 1987): 195–99. http://dx.doi.org/10.1192/bjp.151.2.195.

Texto completo
Resumen
We present 11 pedigrees in which a propositus with Gilles de la Tourette's syndrome had first or second-degree relatives with obsessive-compulsive behaviour or agoraphobia with panic attacks, but only partially expressed the TS gene (i.e. had only motor tics or vocal tics, or neither). Of 90 females over the age of 18 presenting with TS, or with motor or vocal tics alone, nine had severe agoraphobia with panic attacks. There may be genetic subtypes of both obsessive-compulsive disorder and agoraphobia with panic attacks that are due to partial expression of the TS gene.
Los estilos APA, Harvard, Vancouver, ISO, etc.
21

Groszkowski, Jakub. "Sejmiki mazowieckie wobec kwestii sposobu powoływania monarchy w Rzeczypospolitej w okresie Sejmu Wielkiego". Przegląd Sejmowy 4(171) (2022): 57–73. http://dx.doi.org/10.31268/ps.2022.125.

Texto completo
Resumen
The author analyses, on the basis of the parliamentary instructions from the times of the Great Sejm, the attitudes of the Masovian regional assemblies towards one of the key issues of the systemic reform of the electoral monarchy, i.e. the establishment of the hereditary throne in the Republic of Poland. He discusses, differentiates and attempts to explain the reasons for the political behaviour of the nobility from the various lands. The author tries to prove thesis that the vivente rege election in Masovia was adopted as a one-off solution, forced by the political situation of the state. He presents the little-known but original election reform projects put forward by the Masovian nobility. The author explains the reluctance of the Masovian regional assemblies to establish a hereditary throne not by the stereotype of dark and conservative Masovians exposed in historiography, but most of all by the fear that due to economic weakness, the Masovian nobility would lose a significant part of its political importance along with the deprivation of the right to elections.
Los estilos APA, Harvard, Vancouver, ISO, etc.
22

PIN, JEAN-ÉRIC y PEDRO V. SILVA. "ON PROFINITE UNIFORM STRUCTURES DEFINED BY VARIETIES OF FINITE MONOIDS". International Journal of Algebra and Computation 21, n.º 01n02 (febrero de 2011): 295–314. http://dx.doi.org/10.1142/s0218196711006170.

Texto completo
Resumen
We consider uniformities associated with a variety of finite monoids V, but we work with arbitrary monoids and not only with free or free profinite monoids. The aim of this paper is to address two general questions on these uniform structures and a few more specialized ones. A first question is whether these uniformities can be defined by a metric or a pseudometric. The second question is the description of continous and uniformly continuous functions. We first give a characterization of these functions in term of recognizable sets and use it to extend a result of Reutenauer and Schützenberger on continuous functions for the pro-group topology. Next we introduce the notion of hereditary continuity and discuss the behaviour of our three main properties (continuity, uniform continuity, hereditary continuity) under composition, product or exponential. In the last section, we analyze the properties of V-uniform continuity when V is the intersection or the join of a family of varieties and we discuss in some detail the case where V is commutative.
Los estilos APA, Harvard, Vancouver, ISO, etc.
23

Popov, S. N., I. N. Vinnikova y A. S. Berezkin. "Clinical and Social Characteristics of Patients with Schizophrenia and Organic Mental Conditions Who Committed a Repeated Socially Dangerous Act". Doctor.Ru 20, n.º 5 (2021): 62–66. http://dx.doi.org/10.31550/1727-2378-2021-20-5-62-66.

Texto completo
Resumen
Study Objective: To compare clinical and social characteristics of patients with schizophrenia and organic mental conditions who committed a repeated socially dangerous acts (SDAs), not only in order to compare, but also to identify specific SDA risk factors. Study Design: comparative study. Materials and Methods. The study included 86 schizophrenia patients (study group) and 45 patients with organic mental conditions who committed SDAs, were found insane and were forced to undergo various court-appointed therapies for 2 and more times. In this study, we used the clinical psychopathologic method with due account to psychopathology and clinical statistic method as the main methods. Study Results. Hereditary load study demonstrated that in the study group (А) 35 (40.7%) out of 86 patients had hereditary exogenous conditions (pi < 0.05), while in controls (B) 9 (20%) out of 45 patients had such conditions (pi < 0.01). The number of patients without hereditary load was comparable in both groups: 45 (52.3%) vs. 24 (53.3%), respectively. In schizophrenia patients, only 6 (7%) patients had confirmed hereditary endogenous conditions, while in comparison group (B) this value was 9 (20%). Combined hereditary load was recorded only in controls: 3 (6.6%) patients. Almost all patients in comparison group (B) did not have a place work (44 (97.8%); pi < 0.01), while in the study group (A) the unemployed made 44 (51.1%). During the study, 45 (52.3%) patients in group (A) had associated bad habits (alcohol and drug abuse); 14 (16.3%) patients had both alcohol and drug abuse. 23 comparison group (B) patients had various bad habits; combined abuses were recorded in 8 (17.8%) cases. Alcohol and drug abuse were not diagnosed in 20 (23.2%) patients in study group and in 4 (8.9%) patients in controls. Conclusion. Data analysis demonstrates the clinical-social factors are noted in study groups and affect criminal behaviour and a probability of repeated SDAs in the future (with identification of factors specific for each nosological factor group). We have also identified differences in risk factors of a repeated SDA between patients with organic mental disorders and schizophrenia. Keywords: schizophrenia, organic mental disorders, repeated socially dangerous acts.
Los estilos APA, Harvard, Vancouver, ISO, etc.
24

Wiessner, Manuela, Reza Maroofian, Meng-Yuan Ni, Andrea Pedroni, Juliane S. Müller, Rolf Stucka, Christian Beetz et al. "Biallelic variants in HPDL cause pure and complicated hereditary spastic paraplegia". Brain 144, n.º 5 (1 de mayo de 2021): 1422–34. http://dx.doi.org/10.1093/brain/awab041.

Texto completo
Resumen
Abstract Human 4-hydroxyphenylpyruvate dioxygenase-like (HPDL) is a putative iron-containing non-heme oxygenase of unknown specificity and biological significance. We report 25 families containing 34 individuals with neurological disease associated with biallelic HPDL variants. Phenotypes ranged from juvenile-onset pure hereditary spastic paraplegia to infantile-onset spasticity and global developmental delays, sometimes complicated by episodes of neurological and respiratory decompensation. Variants included bona fide pathogenic truncating changes, although most were missense substitutions. Functionality of variants could not be determined directly as the enzymatic specificity of HPDL is unknown; however, when HPDL missense substitutions were introduced into 4-hydroxyphenylpyruvate dioxygenase (HPPD, an HPDL orthologue), they impaired the ability of HPPD to convert 4-hydroxyphenylpyruvate into homogentisate. Moreover, three additional sets of experiments provided evidence for a role of HPDL in the nervous system and further supported its link to neurological disease: (i) HPDL was expressed in the nervous system and expression increased during neural differentiation; (ii) knockdown of zebrafish hpdl led to abnormal motor behaviour, replicating aspects of the human disease; and (iii) HPDL localized to mitochondria, consistent with mitochondrial disease that is often associated with neurological manifestations. Our findings suggest that biallelic HPDL variants cause a syndrome varying from juvenile-onset pure hereditary spastic paraplegia to infantile-onset spastic tetraplegia associated with global developmental delays.
Los estilos APA, Harvard, Vancouver, ISO, etc.
25

Meyer, M., C. M. Kirchmaier, A. Schirmer, P. Spangenberg, Ch Ströhl y K. Breddin. "Acquired Disorder of Platelet Function Associated with Autoantibodies against Membrane Glycoprotein IIb-IIIa Complex - 1. Glycoprotein Analysis". Thrombosis and Haemostasis 65, n.º 05 (1991): 491–96. http://dx.doi.org/10.1055/s-0038-1648178.

Texto completo
Resumen
SummaryA patient with idiopathic thrombocytopenic purpura developed after splenectomy a thrombasthenia-like severe haemor-rhagic diathesis characterized by a normal or subnormal platelet count, prolonged bleeding time, strongly reduced platelet adhesion to glass and defective platelet aggregation in response to ADP and collagen. In contrast to hereditary thrombasthenia membrane glycoproteins (GP) lib and Ilia were normally present in the patient’s platelets. Immunoelectrophoretic analysis revealed an abnormal behaviour of the patient’s GP IIb-IIIa complex. Autoantibodies against GP IIb-IIIa were detected in Triton-extracted washed platelets. Incubation of normal platelets with plasma from the patient resulted in a similar immunoelectrophoretic abnormality of the GP IIb-IIIa complex indicating that bound autoantibodies (IgG) are responsible for the abnormal immunoelectrophoretic behaviour of the patient’s GP IIb-IIIa complex. Platelet fibrinogen was severely reduced similar to classical thrombasthenia suggesting that the GP IIb-IIIa complex is involved in platelet fibrinogen storage.
Los estilos APA, Harvard, Vancouver, ISO, etc.
26

Nikolic, Gordana, Srbobran Miljkovic, Aleksandar Stojkovic, Snezana Manojlovic, Zoran Ciric, Olivera Zikic y Mara Vucurevic. "Influence of psychological and coronary parameters on coronary patient rehospitalization". Srpski arhiv za celokupno lekarstvo 138, n.º 3-4 (2010): 154–61. http://dx.doi.org/10.2298/sarh1004154n.

Texto completo
Resumen
Introduction. Psychological reactions are often comorbid with coronary risk factors and could be important for a six-month outcome. Objective. Determination of anxiety level, depression and aggression, persistence of risk health behaviour, stress life events, and coronary risk factors after coronary event and a predictive value of those parameters for six-month rehospitalization. Methods. In the group with Angina Pectoris (E1=30) and the group with Acute Myocardial Infarction (E2=33), there were applied, at baseline and after 6 months, the following: Semistructured Clinical Interview based on ICD-10, for depressive episode and anxiety disorder, Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD), KON-6 sigma Scale for aggression, Holms-Rahe Scale (H-R) for stress events and Questionnaire for risk behaviour: alcohol consumption, smoking, lack of physical activity. Group differences were assessed by t-test and chi-square test, p<0.05, regression analysis for assessing initial variables, a predictive value for six month rehospitalization. Results. After acute coronary event, the anxiety and depression levels were mild and aggression was low in E1 and mild in E2. Stress event score was significantly higher in E2 (H-R=115.18) than in E1 (H-R=72.20), p<0.05. After 6 months, the results were the same except for a significantly lower stress event score in E1 (H-R=49.48), and in E2 (H-R=91.65), but still significantly higher than in E1. Coronary parameters were reduced, smokers' rate was increased in E1. Alcohol consumption, hypercholesterolaemia and hereditary tendency were predictive for six- month rehospitalization. Conclusion. After acute cardiac event, hospitalized coronary patients had a mild anxiety, depression and aggression level as well as after six months. The infarct patients had experienced more stress life events in the previous year than the angina patients. Risk health behaviour did not change in the following six months, with the increased smokers' rate in the angina group. Alcohol consumption, smoking and heredity were predictive for rehospitalization.
Los estilos APA, Harvard, Vancouver, ISO, etc.
27

Mahajan, R. y P. Gupta. " Molecular markers: their use in tree improvement". Journal of Forest Science 58, No. 3 (27 de marzo de 2012): 137–44. http://dx.doi.org/10.17221/5579-jfs.

Texto completo
Resumen
Earlier breeders used phenotypic selection based on morphological characteristics to improve tree varieties. These selections often take many cycles of breeding and backcrossing in order to place desired characteristics. But today the knowledge has paved the way for a much deeper understanding of the mechanics of cell biology and the hereditary process itself. Breeders are presented with numerous possibilities of altering the behaviour of existing varieties. Linkage between molecular markers can be translated to genetic linkage maps, which have become an important tool in plant genetics. They may choose to use marker-assisted approaches in order to facilitate the selection of favourable combinations of genes that occur naturally within a tree species. &nbsp;
Los estilos APA, Harvard, Vancouver, ISO, etc.
28

Sr, Chrysanthus Chukwuma. "Epigenetics and its essence in understanding human growth, development and disease". Journal of Medical Research 8, n.º 5 (10 de noviembre de 2022): 165–72. http://dx.doi.org/10.31254/jmr.2022.8506.

Texto completo
Resumen
Epigenetics is a scientific discipline encompassing the genetic and non-genetic related perspectives of heritable phenotypic modifications of whose aetiologies include behavioural, anthropogenic, environmental, metabolic and spatiotemporal variables. Behavioral epigenetics examines how epigenetics shapes animal and human behaviour to explicate how nurture moulds nature; nature prefers to biological heredity and nurture prefers to occurrrences in the environment and hereditary during the lifespan of all individuals. Behavioural epigenetics features how experiences and the environment produce individual disparities in behaviour, cognition, personality, and mental health influence gene expression. Epigenetic gene regulation relates to modification of DNA sequence and histones as well as DNA methylation. These epigenetic alterations effect the growth of neurons in the developing brain and functional modification of neurons in the developed brain, with resultant significant alterations in neuron morphology. Epigenetic changes occur in the developing fetus and throughout the lifespan of an individual, with alterations in individual traits and transgenerational inheritance. Epigenetics is associated with heritable changes in gene actions and these are not due to DNA sequence alterations. Epigenetics may be termed sustained, long-run changes in the transcription veracity of a heritable or non-heritable cell. DNA methylation and histone alteration are mechanisms which modify gene expression without changing the underlying DNA sequence. Gene expression is driven by repressor protein actions which bind to DNA silencer regions.DNA methylation turns a gene ''off'' culminating in genetic information impairment to be read from DNA, but extricating the methyl tag can turn ''on'' the gene. Histone alteration defines the packaging of DNA into the chromosomes; and.these changes influence gene expression. This review provides the latitude to examine the extant information in the universal characterizations of epigenetic formulations, such as ageing, susceptibility to pollutant and irritant exposure.
Los estilos APA, Harvard, Vancouver, ISO, etc.
29

Aktan-Collan, Katja, Ari Haukkala y Helena Kääriäinen. "Life and Health Insurance Behaviour of Individuals Having Undergone a Predictive Genetic Testing Programme for Hereditary Non-Polyposis Colorectal Cancer". Public Health Genomics 4, n.º 4 (2001): 219–24. http://dx.doi.org/10.1159/000064196.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
30

Somkina, O. Y., A. V. Merinov y M. A. Baqkova. "Key characteristics of women and men suffering from alcohol dependence in the context of auto-agressive behaviour". I.P.Pavlov Russian Medical Biological Herald 24, n.º 4 (15 de diciembre de 2016): 78–83. http://dx.doi.org/10.23888/pavlovj2016478-83.

Texto completo
Resumen
Aim. To define the clinically and practically significant differences in characteristics of women and men who suffer from alcohol dependency in terms of auto-aggressive behavior associated with alcohol dependence. The article presents the analysis of data obtained in 124 subjects divided into two groups 62 subjects each, women and men suffering from alcohol dependence.Results. The study shows that women and men suffering from alcohol dependence have certain features throughout the course of the disease in the context of the auto-aggressive behavior. Most of the subjects were characterized by a hereditary development of the alcohol dependency represented by the presence of the alcoholism in mothers among 32% of female patients versus 10% among male ones. Women, in general, had more severe alcohol dependence (84% of the female subjects had rapid progression of the disease). The duration of therapeutic remission in most of the cases was less than a year, there were no prolonged therapeutic remissions (3 to 5 years).Conclusion. Women and men have different course of the alcohol dependence, including the auto-aggressive behavioral characteristics, which in turn requires special attention of the medical services that provide narcological and anti-suicidal aid to both female and male patients. Development of gender-specific therapeutic approaches to the treatment of alcohol dependency is also required.
Los estilos APA, Harvard, Vancouver, ISO, etc.
31

Somkina, O. Y., A. V. Merinov y M. A. Baqkova. "Key characteristics of women and men suffering from alcohol dependence in the context of auto-agressive behaviour". I.P.Pavlov Russian Medical Biological Herald 24, n.º 4 (15 de diciembre de 2016): 84–87. http://dx.doi.org/10.23888/pavlovj2016484-87.

Texto completo
Resumen
Aim. To define the clinically and practically significant differences in characteristics of women and men who suffer from alcohol dependency in terms of auto-aggressive behavior associated with alcohol dependence. The article presents the analysis of data obtained in 124 subjects divided into two groups 62 subjects each, women and men suffering from alcohol dependence.Results. The study shows that women and men suffering from alcohol dependence have certain features throughout the course of the disease in the context of the auto-aggressive behavior. Most of the subjects were characterized by a hereditary development of the alcohol dependency represented by the presence of the alcoholism in mothers among 32% of female patients versus 10% among male ones. Women, in general, had more severe alcohol dependence (84% of the female subjects had rapid progression of the disease). The duration of therapeutic remission in most of the cases was less than a year, there were no prolonged therapeutic remissions (3 to 5 years).Conclusion. Women and men have different course of the alcohol dependence, including the auto-aggressive behavioral characteristics, which in turn requires special attention of the medical services that provide narcological and anti-suicidal aid to both female and male patients. Development of gender-specific therapeutic approaches to the treatment of alcohol dependency is also required.
Los estilos APA, Harvard, Vancouver, ISO, etc.
32

Bazovkina, D. y E. Kondaurova. "P.6.b.004 Studying the behavioural effects of ethanol in mice with hereditary predisposition to catalepsy and depressive-like behaviour". European Neuropsychopharmacology 22 (octubre de 2012): S396. http://dx.doi.org/10.1016/s0924-977x(12)70617-x.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
33

Nerizka, Dea, Eva Latipah y A. Munawwir. "FAKTOR HEREDITAS DAN LINGKUNGAN DALAM MEMBENTUK KARAKTER". Jurnal Pendidikan Karakter, n.º 1 (27 de abril de 2021): 55–64. http://dx.doi.org/10.21831/jpk.v0i1.38234.

Texto completo
Resumen
Setiap manusia diciptakan dengan berbagai macam keunikannya dengan karakteristik masing-masing. Faktor hereditas dan lingkungan dipandang sebagai faktor yang mempengaruhi pro- ses pembentukan karakteristik setiap individu. Hereditas dipandang sebagai faktor bawaaan yang di turunkan dari orang tua pada anak baik fisik maupun psikis sejak masa konsepsi melalui gen-gen. Penelitian ini bertujuan untuk mengkaji lebih dalam faktor hereditas dan lingkungan dalam mem- bentuk karakter dengan titik fokus melihat pada faktor manakah yang lebih dominan dalam pemben- tukan karakter individu. Penelitian ini merupakan penelitian kepustakaan. Sumber data dalam peneli- tian ini berupa buku-buku, jurnal dan situs-situs dari internet yang memiliki kaitan dengan topik yang diteliti. Teknik pengumupan data dalam penelitian ini yaitu studi dokumen. Analisis data menggunakan analisis isi (content analysis). Berdasarkan hasil studi yang dilakukan, penulis menemu- kan bahwa faktor hereditas dalam diri individu dipandang mempengaruhi dalam perkembangan jas- mani seperti warna kulit, warna mata, jenis rambut, dan sebagainya. Beberapa bentuk kepribadian dan perilaku sosial dapat merujuk pada faktor lingkungan. HEREDITY AND ENVIRONMENT FACTORS IN BUILDING CHARACTERS Every human being is created with a variety of uniqueness with each characteristic. Here- dity and environmental factors are seen as factors that influence the process of forming the charac- teristics of each individual. Heredity is seen as a hereditary factor that is passed down from parents to children both physically and psychologically since the conception through genes. This study aims to examine more deeply the heredity and environmental factors in shaping character with a focus point to see which factors are more dominant in shaping individual characters. This research is a type of li- brary research. The data sources in this study are books, journals and websites from the internet that are related to the topic under the study. The data collection technique in this research is document stu- dy. The data analysis used content analysis. Based on the results of the study conducted, the authors found that heredity factors in individuals are seen as influencing physical development such as skin color, eye color, hair type, and so on. While some forms of personality and social behavior can refer to environmental factors.
Los estilos APA, Harvard, Vancouver, ISO, etc.
34

Ng, Yong Xian y Chang Phang. "Computation of Stability Criterion for Fractional Shimizu–Morioka System Using Optimal Routh–Hurwitz Conditions". Computation 7, n.º 2 (25 de abril de 2019): 23. http://dx.doi.org/10.3390/computation7020023.

Texto completo
Resumen
Nowadays, the dynamics of non-integer order system or fractional modelling has become a widely studied topic due to the belief that the fractional system has hereditary properties. Hence, as part of understanding the dynamic behaviour, in this paper, we will perform the computation of stability criterion for a fractional Shimizu–Morioka system. Different from the existing stability analysis for a fractional dynamical system in literature, we apply the optimal Routh–Hurwitz conditions for this fractional Shimizu–Morioka system. Furthermore, we introduce the way to calculate the range of adjustable control parameter β to obtain the stability criterion for fractional Shimizu–Morioka system. The result will be verified by using the predictor-corrector scheme to obtain the time series solution for the fractional Shimizu–Morioka system. The findings of this study can provide a better understanding of how adjustable control parameter β influences the stability criterion for fractional Shimizu–Morioka system.
Los estilos APA, Harvard, Vancouver, ISO, etc.
35

Steinert, R., T. Buschmann, M. van der Linden, L. M. Fels, H. Lippert y M. A. Reymond. "The Role of Proteomics in the Diagnosis and Outcome Prediction in Colorectal Cancer". Technology in Cancer Research & Treatment 1, n.º 4 (agosto de 2002): 297–303. http://dx.doi.org/10.1177/153303460200100411.

Texto completo
Resumen
Colorectal cancer is the second most frequent cancer in Western countries. Exogenous factors play a major role in the aetiology of sporadic colorectal cancer representing about 90% of all cases, hereditary cancers accounting for about 10% of patients. Thus, in the large majority of cases, cell dysfunction in CRC results from multiple rather than single, gene interactions. Numerous cellular events and environmental influences modify gene expression or post-translational protein modifications. Changes like glycosylation of proteins and lipids which are a common feature in colorectal cancer and influence cancer cell behaviour, cannot be directly detected by genetic studies. Better than genomics studies, functional proteomics studies allow the investigation of environmental factors over time, allowing the monitoring of metabolic responses to various stimuli. However, proteomics studies also have several drawbacks: a) current tools only allow narrow-range analyses, b) identification of proteins of interest remains cumbersome, c) protein studies address multiple compounds of high complexity, d) large amount of proteins are necessary to allow analysis, e) protein research require specific tools, e.g. tagged antibodies, that first have to be developed. Some protein tests are already in application for CRC: a classical prognostic test in colorectal cancer is based on the detection and quantification of a single protein (CEA) in body fluids. Recently, a screening assay based on APC protein truncation test has also been proposed. However, studies linking large protein expression patterns with clinical outcome in colorectal cancer are still in their infancy. To be able to predict occurrence of disease, and treatment outcome, more studies on genotype-phenotype correlations are needed both in sporadic and in hereditary colorectal cancer.
Los estilos APA, Harvard, Vancouver, ISO, etc.
36

Al-Shami, Tareq y Abdelwaheb Mhemdi. "Two families of separation axioms on infra soft topological spaces". Filomat 36, n.º 4 (2022): 1143–57. http://dx.doi.org/10.2298/fil2204143a.

Texto completo
Resumen
Many generalizations of soft topology were studied in the literature, an infra soft topology is the recent one of these generalizations. In this paper, we put on view two classes of soft separation axioms in the frame of infra soft topologies, namely infra pp-soft Tj and infra pt-soft Tj-spaces (j = 0, 1, 2, 3, 4). Both of them are formulated with respect to distinct ordinary points such that the first class defined using partial belong and partial non-belong relations, and the second one defined using partial belong and total non-belong relations. Following systematic lines of this type of study, we first show the relationships between them with the aid of examples. We also establish main properties and explore their behaviour under some special types of infra soft topologies. Transmission of these classes between infra soft topology and its parametric infra topologies are amply studied. Moreover, we scrutinize their features in terms of hereditary and topological properties, and finite product of soft spaces.
Los estilos APA, Harvard, Vancouver, ISO, etc.
37

Yoshioka, Kantaro, Akira Ito, Masanobu Horie, Kazushi Ikeda, Sho Kataoka, Keiichiro Sato, Taichi Yoshigai et al. "Contractile Activity of Myotubes Derived from Human Induced Pluripotent Stem Cells: A Model of Duchenne Muscular Dystrophy". Cells 10, n.º 10 (27 de septiembre de 2021): 2556. http://dx.doi.org/10.3390/cells10102556.

Texto completo
Resumen
Duchenne muscular dystrophy (DMD) is a genetic disorder that results from deficiency of the dystrophin protein. In recent years, DMD pathological models have been created using induced pluripotent stem (iPS) cells derived from DMD patients. In addition, gene therapy using CRISPR-Cas9 technology to repair the dystrophin gene has been proposed as a new treatment method for DMD. However, it is not known whether the contractile function of myotubes derived from gene-repaired iPS cells can be restored. We therefore investigated the maturation of myotubes in electrical pulse stimulation culture and examined the effect of gene repair by observing the contractile behaviour of myotubes. The contraction activity of myotubes derived from dystrophin-gene repaired iPS cells was improved by electrical pulse stimulation culture. The iPS cell method used in this study for evaluating muscle contractile activity is a useful technique for analysing the mechanism of hereditary muscular disease pathogenesis and for evaluating the efficacy of new drugs and gene therapy.
Los estilos APA, Harvard, Vancouver, ISO, etc.
38

Lin, Jianqiang, Ni Gong, Qianzhong Cao, Yijing Zhou, Yitingxue Cai, Guangming Jin, Charlotte Aimee Young, Jing Yang, Yiyao Wang y Danying Zheng. "What hinders congenital ectopia lentis patients’ follow-up visits? A qualitative study". BMJ Open 10, n.º 3 (marzo de 2020): e030434. http://dx.doi.org/10.1136/bmjopen-2019-030434.

Texto completo
Resumen
ObjectivesThe aim of our study is to give insight into congenital ectopia lentis (CEL) patients’ care-seeking behaviour and explore the factors affecting their follow-up visits.DesignCross-sectional study; in-depth and face-to-face semistructured interview.SettingA large-scale ophthalmology hospital in China.Participants35 patients with CEL and their parents from May 2017 to August 2017.Main outcome measuresThemes and categories. The interviews were audio-recorded, transcribed verbatim, coded and analysed using grounded theory. Data collection was closed when new themes did not emerge in subsequent dialogues.ResultsThe factors affecting the timely visits included insufficient awareness of CEL, shame on hereditary disease, lack of effective doctor–patient communication, lack of reliable information online and daily stressors.ConclusionContinuing medical education of severe and rare disease, reforming the pattern of medical education, constructing an interactive platform of the disease on the internet and improving healthcare policy are effective ways to improve the diagnosis and treatment status of CEL in China.
Los estilos APA, Harvard, Vancouver, ISO, etc.
39

Akowundu, Paulin Karachi, Zainab Aramide Opoola, Usman Olaitan Ibrahim y Foluso Afolabi Lesi. "Adrenoleukodystrophy in a Nigerian boy: A case report and review of literature". Nigerian Journal of Paediatrics 48, n.º 4 (7 de noviembre de 2022): 215–18. http://dx.doi.org/10.4314/njp.v48i4.9.

Texto completo
Resumen
Adrenoleukodystrophy (ALD) is a hereditary, X-linked metabolic disorder with autosomal recessive traits. It arises from mutation in ABCD1 gene on chromosome Xq28. This mutation leads to demyelination of the nervous system, adrenal insufficiency and accumulation of Long Chain Fatty Acids (LCFA). The long chain fatty acids accumulates in tissues throughout the body but the most severely affected tissues are the myelin in the central nervous system, the adrenal cortex and the Leydig cells in the testes. The phenotypic presentations are highly variable which may lead to delayed recognition and misdiagnosis. Most young patients with ALD develop seizures and progressive neurological deficits. It may initially manifest with alterations of behaviour, hearing, vision, speech, gait and in more advanced cases, it results in generalized hypertension, dysphagia and loss of cognitive and motor function. We report a case of adrenoleukodystrophy in a Nigerian boy and also review the existing literature on the condition to increase the awareness and knowledge of this disorder.
Los estilos APA, Harvard, Vancouver, ISO, etc.
40

Sugimoto, N. y H. Hyodo. "Effects of heat conduction in a wall on thermoacoustic-wave propagation". Journal of Fluid Mechanics 697 (6 de marzo de 2012): 60–91. http://dx.doi.org/10.1017/jfm.2012.36.

Texto completo
Resumen
AbstractThis paper examines the effects of heat conduction in a wall on thermoacoustic-wave propagation in a gas, as a continuation of the previous paper (Sugimoto, J. Fluid Mech., 2010, vol. 658, pp. 89–116), enclosed in two-dimensional channels by a stack of plates or in a periodic array of circular tubes, both being subject to a temperature gradient axially and extending infinitely. Within the narrow-tube approximation employed previously, the linearized system of fluid-dynamical equations for the ideal gas coupled with the equation for heat conduction in the solid wall are reduced to single thermoacoustic-wave equations in the respective cases. In this process, temperatures of the gas and the solid wall are sought to the first order of asymptotic expansions in a small parameter determined by the square root of the product of the ratio of heat capacity of gas per volume to that of the solid, and the ratio of thermal conductivity of the gas to that of the solid. The effects of heat conduction introduce into the equation two hereditary terms due to triple coupling among viscous diffusion, thermal diffusion of the gas and that of the solid, and due to double coupling between thermal diffusions of the gas and solid. While the thermoacoutic-wave equations are valid always for any form of disturbances generally, approximate equations are derived from them for a short-time behaviour and a long-time behaviour. For the short-time behaviour, the effects of heat conduction are negligible, while for the long-time behaviour, they will affect the propagation as a wall becomes thinner. It is unveiled that when the geometry of the channels or the tubes, and the combination of the gas and the solid satisfy special conditions, the asymptotic expansions exhibit non-uniformity, i.e. a resonance occurs, and then the thermoacoustic-wave equations break down. Discussion is given on modifications in the resonant case by taking full account of the effects of heat conduction, and also on the effects on the acoustic fields.
Los estilos APA, Harvard, Vancouver, ISO, etc.
41

Alfaar, Ahmad Samir, Anas Saad, Shiema Elzouki, Mohamed H. Abdel-Rahman, Olaf Strauss y Matus Rehak. "Uveal melanoma-associated cancers revisited". ESMO Open 5, n.º 6 (noviembre de 2020): e000990. http://dx.doi.org/10.1136/esmoopen-2020-000990.

Texto completo
Resumen
BackgroundUveal melanoma (UM) is the most common primary ocular malignancy of adults. A small group of patients was found to express familial predisposition. Moreover, it may be preceded or followed by other malignancies elsewhere in the body. We aim to compare the incidence of UM and other associated cancers and study the factors that may influence each condition.Patients and methodsWe have collected the data from the Surveillance, Epidemiology and End Results database of nine US cancer registries for UM patients between 1973 and 2015. We calculated the standardised incidence ratios for single primary UM, first primary and second primary UM, and compared the groups for multiple factors.ResultsA total of 4946 patients were included in the study; 3863 with single primary UM, 646 developed a second primary malignancy following UM, and 437 patients developed second primary UM following a previous primary malignancy. The risk of developing UM increased after leukaemia, melanoma of the skin and prostate. On the other side, the risk of developing melanoma of the skin, thyroid, renal and other eye and orbit malignancies has increased significantly after initial UM. This risk was more evident in the age group between 50 and 70 years old. Cancer-specific survival was significantly higher in UM associated with other malignancies group compared with single primary UM.ConclusionOur study showed a different behaviour of the UM when associated with other tumours that exceed the known spectrum of hereditary UM. Further studies are required to dissect the genetic background of this behaviour.
Los estilos APA, Harvard, Vancouver, ISO, etc.
42

McMillan, Alan D. "Non-Human Whalers in Nuu-chah-nulth Art and Ritual: Reappraising Orca in Archaeological Context". Cambridge Archaeological Journal 29, n.º 2 (4 de febrero de 2019): 309–26. http://dx.doi.org/10.1017/s0959774318000549.

Texto completo
Resumen
Whaling was a central aspect of Nuu-chah-nulth, Ditidaht and Makah culture on the northwest coast of North America. Not only was it economically important, it was vital to chiefly prestige. Art and ceremonial life were dominated by themes related to whaling. Thunderbird, the great supernatural whaler, was the source of hereditary prerogatives held by chiefs, including names, dances, regalia and rights to display images of thunderbird and whale. This paper argues that human observations of predatory behaviour by orcas (or killer whales) led to these animals also being perceived as non-human whalers from which chiefly prerogatives could be obtained. Wolves, the main figures in Nuu-chah-nulth ceremonial life, had the power to transform into orcas, explaining their frequent presence in the art with thunderbirds and whales. This paper presents archaeological evidence for orca in the context of whaling and offers interpretations based on the extensive ethnographic and oral historical records. It also places perceptions of animals, the role of the hunter's wife and beliefs about orca in a broader context involving hunting societies in northwestern North America.
Los estilos APA, Harvard, Vancouver, ISO, etc.
43

Hemmings, A. J. y S. D. McBride. "Brain based phenotypic differences occurring in crib-biting horses: continuing the search for a heritable component". BSAP Occasional Publication 35 (2006): 275–78. http://dx.doi.org/10.1017/s0263967x00042890.

Texto completo
Resumen
Approximately 8% of European performance horses engage in cribbiting behaviour (McGreevy et al.,1995, Redbo et al., 1998), a trait which can reduce both financial value and welfare status of the animal. An increase in prevalence to 26% was reported in those families originating from crib-biting sires (Vecchiotti and Galantini 1986), tentatively implying that a genetic component may be involved. Indeed, in a herd of Przewalski's horse, there was an 84% chance of offspring crib-biting if they originated from cribbing parents (Marsden and Henderson 1994). Finally, hereditary transmission has been more reliably demonstrated in the rodent, where stereotypy can be induced following 9 days of food restriction in the highly inbred DBA mouse strain, but not the C57 strain (Cabib and Bonaventura 1997) suggesting 1) propagation of a genetic component within the DBA genotype and 2) the requirement of an environmental stressor for stereotypy development. In the rodent model this genetic pre-disposition manifests physiologically as a facilitation of dopamine transmission within the mesolimbic projection following a period of stress (Cabib et al., 1998).
Los estilos APA, Harvard, Vancouver, ISO, etc.
44

Ispolatov, Iaroslav, Martin Ackermann y Michael Doebeli. "Division of labour and the evolution of multicellularity". Proceedings of the Royal Society B: Biological Sciences 279, n.º 1734 (7 de diciembre de 2011): 1768–76. http://dx.doi.org/10.1098/rspb.2011.1999.

Texto completo
Resumen
Understanding the emergence and evolution of multicellularity and cellular differentiation is a core problem in biology. We develop a quantitative model that shows that a multicellular form emerges from genetically identical unicellular ancestors when the compartmentalization of poorly compatible physiological processes into component cells of an aggregate produces a fitness advantage. This division of labour between the cells in the aggregate occurs spontaneously at the regulatory level owing to mechanisms present in unicellular ancestors and does not require any genetic predisposition for a particular role in the aggregate or any orchestrated cooperative behaviour of aggregate cells. Mathematically, aggregation implies an increase in the dimensionality of phenotype space that generates a fitness landscape with new fitness maxima, in which the unicellular states of optimized metabolism become fitness saddle points. Evolution of multicellularity is modelled as evolution of a hereditary parameter: the propensity of cells to stick together, which determines the fraction of time a cell spends in the aggregate form. Stickiness can increase evolutionarily owing to the fitness advantage generated by the division of labour between cells in an aggregate.
Los estilos APA, Harvard, Vancouver, ISO, etc.
45

Olodo, E. T., E. C. Adjovi y V. Adanhounme. "Identification of Heredity Kernels and Their Influence on the Life Time of Glass/Polyester Composites". International Journal of Applied Mechanics and Engineering 19, n.º 4 (1 de noviembre de 2014): 725–34. http://dx.doi.org/10.2478/ijame-2014-0050.

Texto completo
Resumen
Abstract One of the major problems encountered in prediction of hereditary viscoelastic behavior of polymeric composites is the determination of heredity kernels. This issue comes down to identification of the model characterizing the viscoelastic properties of these materials. The purpose of this work is to propose a model for prediction of viscoelastic nonlinear behavior of laminate composite with polyester matrix, through the study and analysis of heredity kernels and their influence on the life time of this material. Identification of this model required experimental determination at room temperature, of viscoelastic parameters of heredity kernels by macroscopic approach. These data provide predictive tools for establishment of the life time and long term stress limit under static complex loading for this type of material.
Los estilos APA, Harvard, Vancouver, ISO, etc.
46

Nur Amini y Naimah Naimah. "FAKTOR HEREDITAS DALAM MEMPENGARUHI PERKEMBANGAN INTELLIGENSI ANAK USIA DINI". Jurnal Buah Hati 7, n.º 2 (30 de septiembre de 2020): 108–24. http://dx.doi.org/10.46244/buahhati.v7i2.1162.

Texto completo
Resumen
Heredity is defined as the totality of individual characteristics inherited from parents to children, or all potential, both physical and psychological, that an individual has since the conception (fertilization of the ovum by sperm) as inheritance from parents through genes. The genes a child receives from its parents at conception will affect all the characteristics and appearance of the child in the future. As for what parents pass down to their children is structural characteristics, not behavior obtained as a result of learning or experiences such as talents, hereditary traits, intelligence and also personality. This heredity factor has a greater influence on the development of a child's intelligence than the other two factors, namely environmental factors and general factors. Therefore, the researcher wants to examine more deeply the heredity factor (heredity) in influencing the development of early childhood intelligence. This research is a qualitative descriptive field research. Where the type of research used is the type of library research (library research), which is a study conducted in the library room to find and analyze data sourced from the library, whether in the form of books, magazines, newspapers, and so on. The data collection technique used by researchers is the documentation method, namely the method of collecting data or information by reading books, letters, announcements, meeting summaries, written statements, and other similar materials. Abstrak Hereditas diartikan sebagai totalitas karakteristik individu yang diwariskan orangtua kepada anak, atau segala potensi, baik fisik maupun psikis yang dimiliki individu sejak masa konsepsi (pembuahan ovum oleh sperma) sebagai pewarisan dari orangtua melalui gen-gen. Gen yang diterima anak dari orang tuanya pada saat pembuahan akan mempengaruhi semua karakteristik dan penampilan anak kelak. Adapun yang diturunkan orangtua kepada anaknya adalah sifat strukturnya bukan tingkah laku yang diperoleh sebagai hasil belajar atau pengalaman seperti bakat, sifat-sifat keturunan, intelligensi dan juga kepribadiannya. Faktor hereditas ini memberikan pengaruh lebih besar terhadap perkembangan intelligensi seorang anak dibanding dua faktor lainnya yaitu faktor lingkungan dan faktor umum. Maka dari itu peneliti ingin mengkaji lebih dalam faktor hereditas (keturunan) tersebut dalam mempengaruhi perkembangan intelligensi anak usia dini. Penelitian ini merupakan penelitian lapangan yang bersifat deskriptif kualitatif. Dimana jenis penelitian yang digunakan adalah jenis penelitian kepustakaan (library research), yaitu suatu penelitian yang dilakukan di ruang perpustakaan untuk mencari dan menganalisis data yang bersumber dari perpustakaan, baik berupa buku, majalah, koran, dan lain sebagainya. Teknik pengumpulan data yang digunakan peneliti adalah metode dokumentasi, yakni metode pengumpulan data atau informasi dengan cara membaca buku-buku, surat-surat, pengumuman, iktisar rapat, pernyataan tertulis, dan bahan-bahan sejenis lainnya. Kata Kunci : Faktor Hereditas, Perkembangan Intelligensi Anak Usia Dini
Los estilos APA, Harvard, Vancouver, ISO, etc.
47

Nurasia Natsir, Yuliyanah Sain y Nuraziza Aliah. "PERAN PSIKOLOGI DALAM PERKEMBANGAN KOGNITIF DAN LINGUISTIK PADA ANAK". JOURNAL OF ADMINISTRATIVE AND SOCIAL SCIENCE 3, n.º 1 (1 de enero de 2022): 1–8. http://dx.doi.org/10.55606/jass.v3i1.1.

Texto completo
Resumen
In human development, it is often characterized as a developmental milestone where new behaviors emerge and are increasingly complex as the stages of development appear in this modern era. Development does notoccur at a constant pace. A relatively fast growth (spurt) can be interspersed with slow growth (plateau).Some scholars use such uneven patterns of growth and change as evidence of qualitatively different periods of development. From the results of the study found 3 factors that have the potential to affect the development of each child's reasoning,namely; Hereditary factors (heredity), environmental factors, heredity and environmental factors that interact to form behavior. The characteristics inherited by each child have a sensitive period, namely when children are active and motivated learners and when children construct their knowledge based on experience. In implanting physical and cognitive devices there is thought and language becoming increasingly interdependent; As thought and language begin to fuse, children often talk to themselves which is known as self-talk. Self-talk has an important function in cognitive development: By talking to themselves, children learn to guide and direct their own behavior in the process of performing difficult tasks and performing complex maneuvers_just as adults guide them.
Los estilos APA, Harvard, Vancouver, ISO, etc.
48

Linge, Abdiansyah y Upi Sopiah Ahmad. "ENTREPRENUERSHIP DALAM PERSPEKTIF ALQURAN DAN ETNOLOGI". BISNIS : Jurnal Bisnis dan Manajemen Islam 4, n.º 2 (9 de diciembre de 2016): 1. http://dx.doi.org/10.21043/bisnis.v4i2.2687.

Texto completo
Resumen
Alquran is a guidance of life for the people to get prosperity in<br />the world and beyond, Alquran implement a concept to<br />combine both of them. Economic activities is also studied in<br />holy quran, where holy quran talk about teory and concept in<br />economic system. One of studies that interest in this research<br />that have corelation with enterpreneurship, as an eforts to<br />develope human quality. Many of variable that influence<br />behaviour of person to do economic activities one of them is<br />culture. This research means to interest the people do<br />enterpreneurship and to increase it by using Alquran as<br />guidance.This study used a qualitative approach, with shades<br />of library research (library Risearch). This study also aims to<br />determine the Qur'anic concept of entreprenuership, as well as<br />ethnology relation to the formation of a person's interest to<br />behave entreprenuership. Patterned with qualitative research<br />literature research can be concluded: the Qur'an has economic<br />theories with the concept tijarah including entreprenuership.<br />The concept and value of economic value contained in the<br />Qur'an into the basic motivation of behavior entreprenuers<br />Muslims, the Qur'an which emphasizes benefit of the people,<br />justice that promotes ethical behavior in each business process,<br />became the basic philosophy in conducting economic activities,<br />including the activities entreprenuership. Second, the idea of<br />the results of the concept of human thought and activity in the<br />form of economic behavior contained in a culture that became<br />hereditary behavior in public when adjusted to the economic<br />value contained in the Qur'an will awaken the concept or<br />theory about sharia entreprenuership.
Los estilos APA, Harvard, Vancouver, ISO, etc.
49

Noviana, Fajria y Akhmad Saifudin. "Conceptual Metaphors of “water” in Javanese Proverbs from a Cognitive Linguistic Perspective". E3S Web of Conferences 317 (2021): 02014. http://dx.doi.org/10.1051/e3sconf/202131702014.

Texto completo
Resumen
This paper examines how the Javanese views the concept of water. Water is one of the natural elements whose existence is essential for humans. This study examines Javanese proverbs containing the word “water” or banyu in Javanese through a qualitative paradigm and a cognitive linguistic approach. Data were obtained from the Javanese Proverbs Dictionary by Darmasoetjipta. Proverbs are used as the object of study, considering that proverbs are one of the language products of a culture born based on the experience of human interaction with nature or the world and has been hereditary believed to be one of the guidelines or advice for life. The proverb contains metaphors so that in examining it, this research uses conceptual metaphor theory. Metaphor is not simply a language feature; it is also an embodiment of human nature. Metaphor is an effective cognitive tool to study how the human thinking mechanism is, how humans perceive reality in an image schema, map it in cognition, and express it through language. Based on the data analysis, it was found that water, according to the Javanese, is seen as a conceptualization of ideological values used as guidelines in social behaviour and social relationships.
Los estilos APA, Harvard, Vancouver, ISO, etc.
50

PHILLIPS, IAIN y IREK ULIDOWSKI. "A hierarchy of reverse bisimulations on stable configuration structures". Mathematical Structures in Computer Science 22, n.º 2 (28 de febrero de 2012): 333–72. http://dx.doi.org/10.1017/s0960129511000429.

Texto completo
Resumen
Van Glabbeek and Goltz (and later Fecher) have investigated the relationships between various equivalences on stable configuration structures, including interleaving bisimulation (IB), step bisimulation (SB), pomset bisimulation and hereditary history-preserving (H-H) bisimulation. Since H-H bisimulation may be characterised by the use of reverse as well as forward transitions, it is of interest to investigate these and other forms of bisimulations where both forward and reverse transitions are allowed. Bednarczyk asked whether SB with reverse steps is as strong as H-H bisimulation. We answer this question negatively. We give various characterisations of SB with reverse steps, showing that forward steps do not add power. We strengthen Bednarczyk's result that, in the absence of auto-concurrency, reverse IB is as strong as H-H bisimulation, by showing that we need only exclude auto-concurrent events at the same depth in the configuration.We consider several other forms of observations of reversible behaviour and define a wide range of bisimulations by mixing the forward and reverse observations. We investigate the power of these bisimulations and represent the relationships between them as a hierarchy with IB at the bottom and H-H at the top.
Los estilos APA, Harvard, Vancouver, ISO, etc.
Ofrecemos descuentos en todos los planes premium para autores cuyas obras están incluidas en selecciones literarias temáticas. ¡Contáctenos para obtener un código promocional único!

Pasar a la bibliografía