Literatura académica sobre el tema "GST"

Crea una cita precisa en los estilos APA, MLA, Chicago, Harvard y otros

Elija tipo de fuente:

Consulte las listas temáticas de artículos, libros, tesis, actas de conferencias y otras fuentes académicas sobre el tema "GST".

Junto a cada fuente en la lista de referencias hay un botón "Agregar a la bibliografía". Pulsa este botón, y generaremos automáticamente la referencia bibliográfica para la obra elegida en el estilo de cita que necesites: APA, MLA, Harvard, Vancouver, Chicago, etc.

También puede descargar el texto completo de la publicación académica en formato pdf y leer en línea su resumen siempre que esté disponible en los metadatos.

Artículos de revistas sobre el tema "GST"

1

Krajcevski, Pavel, Srihari Pratapa y Dinesh Manocha. "GST". ACM Transactions on Graphics 35, n.º 6 (11 de noviembre de 2016): 1–10. http://dx.doi.org/10.1145/2980179.2982439.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
2

Helfer, R. y G. Taeschler. "GST". Schweizer Archiv für Tierheilkunde 154, n.º 6 (1 de junio de 2012): 266–69. http://dx.doi.org/10.1024/0036-7281/a000344.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
3

Hutchinson, Dan. "GST UPDATE". Australian Veterinary Journal 78, n.º 6 (junio de 2000): 372. http://dx.doi.org/10.1111/j.1751-0813.2000.tb11804.x.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
4

Katzman, Neil Bernard. "GST Rebates". Canadian Pharmacists Journal / Revue des Pharmaciens du Canada 139, n.º 4 (julio de 2006): 7. http://dx.doi.org/10.1177/171516350613900404.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
5

Lasnier, Elisabeth. "Alpha GST". EMC - Biologie Médicale 1, n.º 1 (enero de 2006): 1–2. http://dx.doi.org/10.1016/s2211-9698(06)76019-8.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
6

Douillet, Christelle, Beverly H. Koller y Miroslav Stýblo. "Metabolism of Inorganic Arsenic in Mice Lacking Genes Encoding GST-P, GST-M, and GST-T". Chemical Research in Toxicology 33, n.º 8 (23 de julio de 2020): 2043–46. http://dx.doi.org/10.1021/acs.chemrestox.0c00273.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
7

Ram, Nimishakavi. "GST Audit - "Questionnaire"". Management Accountant Journal 54, n.º 8 (31 de agosto de 2019): 36. http://dx.doi.org/10.33516/maj.v54i8.36-37p.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
8

N, Ramya. "Challenges of gst". Journal of Management and Science 7, n.º 2 (30 de junio de 2017): 334–37. http://dx.doi.org/10.26524/jms.2017.49.

Texto completo
Resumen
It has been long pending issue to streamline all the different types of indirect taxes andimplement a ―single taxation‖ system. This system is called as GST ( GST is the abbreviatedform of Goods & Services Tax). The main expectation from this system is to abolish allindirect taxes and only GST would be levied. As the name suggests, the GST will be leviedboth on Goods and Services.GST was first introduced during 2007-08 budget session. On 17th December 2014, the currentUnion Cabinet ministry approved the proposal for introduction GST ConstitutionalAmendment Bill. On 19th of December 2014, the bill was presented on GST in Loksabha.The Bill will be tabled and taken up for discussion during the coming Budget session. Thecurrent central government is very determined to implement GST Constitutional AmendmentBill.
Los estilos APA, Harvard, Vancouver, ISO, etc.
9

Anon, Anon. "Indirect Taxes - GST". Management Accountant Journal 55, n.º 3 (31 de marzo de 2020): 113. http://dx.doi.org/10.33516/maj.v55i3.113-114p.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
10

Krever, Rick. "The new GST". Monash Business Review 4, n.º 2 (julio de 2008): 46–48. http://dx.doi.org/10.2104/mbr08034.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.

Tesis sobre el tema "GST"

1

Atar, Murat [Verfasser]. "Synthese und photophysikalische Untersuchung von phthalimidbasierten modularen Fluoreszenzsonden zur Detektion von ROS, GSH/GST und Cyanid / Murat Atar". München : Verlag Dr. Hut, 2018. http://d-nb.info/1161250433/34.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
2

Irtem, Kartal Deniz. "The Expression Of Gst Genes In Diabetic Rat Liver Tissues". Master's thesis, METU, 2008. http://etd.lib.metu.edu.tr/upload/12610081/index.pdf.

Texto completo
Resumen
Free radicals which have critical roles in living systems through their beneficial and detrimental effects play an important role in medical revolution in health. Radicals are produced in the cells and tissues of our bodies by various processes and reactions. Diabetes mellitus is an extremely common disease in the world which seems to be accompanied by a shortage of antioxidants and an increase in free radicals, the end result of oxidative stress. Glutathione S-Transferases (GST
EC 2.5.1.18) are found in enzymatic defense system which has a role in defending cells against potentially toxic and/or carcinogenic compounds. In this study, the changes in the activities and expressions of various GST isozymes in the liver of diabetic rats related to oxidative stress were studied. The effects of antioxidants, Vitamin C and &
#945
-Lipoic acid on GST isozyme activities and mRNA expressions were also investigated. According to our results, diabetic rats exhibited decreased mRNA expressions of both GSTA2 and GSTM1 genes, but the activities of only GST Mu isozyme decreased in diabetic rats, compared to controls and GST Alpha isozyme activity remained unchanged in diabetic animals. Our results also showed that &
#945
-Lipoic acid individually has no significant effect on both GSTA2 and GSTM1 gene expressions and activities. Furthermore, although the administration of Vitamin C alone showed no significant effect on all GST isozyme activities, it decreased GSTA2 mRNA expression significantly. The administration of Vitamin C and &
#945
-Lipoic acid together affected both GSTA2 and GSTM1 mRNA expressions in control rats, but only GST Mu activity showed a significant change. The results of this study showed that, the administration of two antioxidants, &
#945
-Lipoic acid and Vitamin C alone and together did not reverse the results of diabetes at the level of both gene expression and activities of GST isozymes.
Los estilos APA, Harvard, Vancouver, ISO, etc.
3

Salmonowicz, Daniel J. "Creation of a Unique GST-FAK Plasmid for Protein Expression". Ohio Dominican University Honors Theses / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=oduhonors1588678705964411.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
4

Utiumi, Kiyoko Uemura. "Avaliação da resposta imune humoral em camundongos para a proteína glutationa s-transferase de Rhipicephalus (Boophilus) microplus (GST-Bm), e de haemaphysalis longicornis (GST-HI)". reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2008. http://hdl.handle.net/10183/12432.

Texto completo
Resumen
O carrapato Rhipicephalus (Boophilus) microplus é um ectoparasito hematófago que infesta os rebanhos bovinos de regiões tropicais e subtropicais, e é um dos principais causadores de prejuízos econômicos à pecuária. O principal método de controle baseia-se no uso de acaricidas. No entanto, devido à crescente preocupação com os problemas criados pela poluição química do meio ambiente, ao alto custo e toxicidade das drogas e ao aparecimento de carrapatos resistentes aos acaricidas, métodos alternativos para o controle do R. microplus devem ser encontrados. Um dos métodos alternativos estudados é o uso de vacinas. As glutationa S-transferases (GST) são enzimas que estão presentes em organismos animais e vegetais e entre suas funções podem-se destacar transporte intracelular, participação em processos digestivos, síntese de prostaglandinas, e detoxificação de substâncias tóxicas e proteção contra estresse oxidativo. Neste estudo foi analisada a resposta imunológica comparativa de camundongos para a GST de R. microplus (GST-Bm) e para a GST de Haemaphysalis longicornis (GST-Hl). Ambas as proteínas foram expressas em Escherichia coli linhagem AD494, e purificadas por cromatografia de afinidade por glutationa utilizando a coluna GSTrap FF. Para verificar a imunogenicidade das proteínas, foram utilizados 25 camundongos Balb/c divididos em 12 grupos. As condições testadas foram as inoculações das proteínas GST-Bm e GST-Hl com os adjuvantes Montanide, saponina ou sem adjuvantes. Camundongos controle foram inoculados com extrato de E. coli ou somente com os adjuvantes. Foi coletado sangue de todos os animais com intervalos de sete dias durante 70 dias. Os soros foram analisados por ELISA para acompanhar a cinética da produção de anticorpos de todos os animais imunizados. Os camundongos inoculados com GST-Hl emulsificada com Montanide mostraram aumento dos níveis de anticorpos a partir do dia 21. O nível máximo de anticorpos foi detectado no dia 42, e diminuiu após o dia 56. Todos os outros animais não apresentaram aumento nos níveis de anticorpos.
Rhipicephalus (Boophilus) microplus tick is a hematophagous ectoparasite that infests cattle in tropical and subtropical regions and is one of the principal causes of economic losses in the cattle farm. The principal method of control is the use of acaricides. However, due to increased worry about environmental chemical pollution, high costs and drugs toxicity and the selection of ticks resistant to acaricides, alternative methods for R. microplus control should be developed. One of these methods is vaccination. Glutathione S-transferases (GSTs) enzymes are present in animal and vegetal organisms and the functions are intracellular transport, participation in digestive process, synthesis of prostaglandins and detoxification of toxic substances and protection against oxidative stress. In this study the immunological response of mice inoculated with R. microplus GST (GST-Bm) and with Haemaphysalis longicornis GST (GST-Hl) was analysed. Both proteins were expressed in Escherichia coli strain AD494 and were purified by affinity chromatography using GSTrap FF columm. To verify the protein immunogenicity, 25 Balb/c mice divided into 12 groups were used. The tested conditions were inoculation of GST-Bm, GST-Hl proteins with Montanide and saponin adjuvants or without adjuvant. Control mice were inoculated with E. coli extract or the adjuvant alone. Blood from all animals were collected with intervals of seven days during seventy days, the sera were analyzed by ELISA to verify the kinetic of antibodies production of all immunized animals. Mice inoculated with GST-Hl emulsified with Montanide showed an increase in the antibodies levels from day 21. The maximum level of antibodies was detected on day 42 and decreased after day 56. The other animals did not show an increase in antibodies levels.
Los estilos APA, Harvard, Vancouver, ISO, etc.
5

Ribeiro, Junior Anicezio de Paula. "ANÁLISE DOS POLIMORFISMOS DO GENE GSTM1 EM AMOSTRAS DE PTERÍGIO EM GOIÂNIA-GOIÁS". Pontifícia Universidade Católica de Goiás, 2014. http://localhost:8080/tede/handle/tede/2378.

Texto completo
Resumen
Made available in DSpace on 2016-08-10T10:38:49Z (GMT). No. of bitstreams: 1 ANICEZIO DE PAULA RIBEIRO JUNIOR.pdf: 2091897 bytes, checksum: eeef0e9bac88a2e48f8d2f33adf5d0d2 (MD5) Previous issue date: 2014-06-18
The first reports about pterygium date back to Hippocrates. This disease still hides mysteries about its pathogenesis in a way that even today it threaten vision health of many people around the world. It is a formation of fibrous tissue that grows excessively and with an abnormal shape on the cornea The anomaly consists of epithelial and subepithelial tissue and it is highly vascularized. A large number of factors are associated with the pathogenesis of pterygium such as physical factors: heat, dust and other particles in the atmosphere; and biological factors such as immunological mechanisms, mechanisms that involve the reorganization of the extracellular matrix, growth factors, cytokines, apoptosis, and angiogenic factors. The pterygium affects individuals who mainly inhabit tropical countries located near the equator and who working out in the sun; thus, the incidence is higher in the region between 40 degrees latitude north and south of the Equator. Considering the need to further investigate the association between GSTM1 polymorphisms and the formation of pterygium, this paper aims to analyze this relationship. The analysis of the null polymorphism of the GSTM1 gene for the case group found a significant difference between the GSTM1 null genotype in case and control groups. The null genotype of the GSTM1 gene is statistically significant in males, but not in female. The null genotype of the GSTM1 gene is statistically significant in Caucasians, but not in Brown or Black. The GSTM1 null genotype is not related to the risk factors analyzed: cases in family, occupational exposure, smoking, hypertension and diabetes.
Os primeiros relatos sobre pterígio datam da época de Hipócrates, mesmo assim essa condição ainda esconde mistérios sobre sua patogenia de forma tal que ainda nos dias de hoje pode ameaçar a saúde da visão de inúmeras pessoas. É uma formação fibrosa de conjuntiva cresce exageradamente e de forma anormal sobre a córnea, sendo composta por tecido epitelial e subepitelial, e altamente vascularizada. Um grande número de fatores está relacionado com a patogenia do pterígio tais como, aspectos físicos, calor, poeira e outras partículas presentes na atmosfera; e fatores biológicos como certos mecanismos imunológicos, mecanismos que envolvem a reorganização da matriz celular, fatores de crescimento, citocinas, apoptose e fatores angiogênicos. O pterígio acomete indivíduos que habitam principalmente países de clima tropical, localizados próximo à linha do Equador e que trabalham expostos ao sol; assim, a incidência é maior na região entre 40 graus de latitude ao norte e ao sul do Equador. Considerando a necessidade de investigar melhor a associação entre os polimorfismos do GSTM1 e a formação do pterígio, o presente trabalho tem o objetivo analisar essa relação. A análise do polimorfismo do gene GSTM1 para o grupo caso constatou que há diferença significativa entre o genótipo nulo do gene GSTM1 nos grupos caso e controle. O genótipo nulo do gene GSTM1 é estatisticamente significante na população masculina, mas não na feminina. O genótipo nulo do gene GSTM1 é estatisticamente significante na etnia branca, mas não na parda ou negra. O genótipo nulo do gene GSTM1 não está relacionado aos fatores de risco analisados: casos na família, exposição ocupacional, fumo, hipertensão e diabetes.
Los estilos APA, Harvard, Vancouver, ISO, etc.
6

Sheppard, Hilary Morna. "Characterisation of cis-elements in the GST-27 promoter of Zea mays". Thesis, University of Leicester, 1996. http://hdl.handle.net/2381/35150.

Texto completo
Resumen
The ability to control the expression of selected genes has many applications both in industry and academic research. The 27 kDa subunit of the glutathione S-transferase II (GST-27) gene in maize is not transcribed in the aerial organs of maize during normal growth and development. However, it can be induced by treatment with herbicide safeners (e.g. dichlormid) resulting in high levels of expression. Since the promoter of this gene may be useful as a tool to control the expression of other genes, we have investigated the molecular basis of its induction by the identification of the cis-acting promoter elements involved. Safeners also induce the production of enzymes and substrates which are involved in a plant's defense against pathogen attack and in combating oxidative stress. Thus, information relating to GST-27 induction may also add to our knowledge relating to these other responses. Deletion analysis of the GST-27 promoter was carried out by transient expression of GST- 27::GUS transcriptional fusions in Black Mexican Sweet (BMS) maize cells. These experiments indicated that a 378 base pair region of the promoter can confer safener-inducibility on GUS expression. This region of the promoter was in vivo footprinted and four putative safener-responsive elements were thus identified (regions in which G residues are protected when the gene is expressed). These elements are similar to each other and to an ethylene responsive element in the GST1 gene of carnation. Electrophoresis mobility-shift assays indicated that one or more nuclear proteins from maize leaves specifically interact with all of the elements. These elements were mutated in GST-27::GUS constructs, which were tested in transient assays in BMS cells in order to obtain direct evidence for their involvement in safener-dependent transcription. The transient assay technique was, however, found to be insufficiently sensitive for this purpose. The GST-27::GUS constructs containing mutations of the putative elements were therefore tested in transgenic tobacco. The 570 base pairs of the wild type GST-27 promoter upstream of the transcription start point was found to retain inducibility in transgenic tobacco plants, but a 378 base pair GST-27::GUS transcriptional fusion (which was inducible in BMS maize cell lines) was not inducible when tested in tobacco. In order to test for loss of function, mutations of the putative safener-responsive elements were introduced into the 378 base pair truncated promoter; in order to test for a gain of function the putative elements were fused to the -60 and -90 35S cauliflower mosaic virus minimal promoters and tested in stable tobacco transformants. These experiments did not, however, prove that these elements play a role in safener-dependent transcription. Surprisingly, the -90 minimal promoter itself was found to be responsive to safener. A previously characterised cis-element, activation sequence-1 (as-1), is contained within the -90 minimal promoter and may account for its inducibility; a similar element is present in the GST-27 promoter but its role in safener-dependent transcription, if any, is unclear.
Los estilos APA, Harvard, Vancouver, ISO, etc.
7

NASCIMENTO, Luiz Eduardo Alves Bezerra do. "Efeitos letais e subletais do fenantreno e pireno em recém-nascidos do peixe Poecilia vivipara". Universidade Federal de Pernambuco, 2015. https://repositorio.ufpe.br/handle/123456789/17375.

Texto completo
Resumen
Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2016-07-14T14:31:03Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Dissertação Luiz Eduardo Alves Bezerra do Nascimento.pdf: 898152 bytes, checksum: 6a9c77c38d08afcb99b849e2f5b50493 (MD5)
Made available in DSpace on 2016-07-14T14:31:03Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Dissertação Luiz Eduardo Alves Bezerra do Nascimento.pdf: 898152 bytes, checksum: 6a9c77c38d08afcb99b849e2f5b50493 (MD5) Previous issue date: 2015-11-30
CAPEs
Poecilia vivipara apresenta distribuição ampla na costa brasileira, e sua reprodução por viviparidade viabiliza a utilização de jovens recém-nascidos com 24 horas de vida em estudos ecotoxicológicos para avaliar o potencial de toxicidade de contaminantes ambientais. Este trabalho teve por objetivos avaliar os efeitos letais e subletais nestes estágios iniciais de vida do peixe estuarino Poecilia vivipara após exposição a diferentes concentrações dos HPAs fenantreno e pireno dissolvidos na água. Os jovens recém-nascidos foram obtidos de plantel de reprodutores mantidos em laboratório, expostos ao fenantreno nas concentrações 0, 10, 50, 200 e 500 μg L-1 durante 7 dias, e ao pireno nas concentrações 0, 1, 10, 50 e 100 μg L-1 durante 14 dias. Após a exposição foi avaliada a taxa de mortalidade, e nos sobreviventes foram quantificados os parâmetros subletais atividade da Glutationa S-Transferase (GST), velocidade de natação espontânea, captura de presas e crescimento. Jovens expostos a 500 μg fenantreno L-1 apresentaram 40% de mortalidade, e não foi detectada mortalidade nas demais concentrações. Jovens expostos ao pireno nas concentrações 50 e 100 μg L-1 apresentaram 44% e 33% de mortalidade, respectivamente, e não foi detectada mortalidade nas demais concentrações. Com relação aos parâmetros subletais, a concentração de efeito observado (CEO) para atividade de GST, velocidade média de natação, distância linear nadada e incremento de peso foi igual a 500 μg fenantreno L-1. Já para a exposição ao pireno a (CEO) para atividade de GST foi igual a 10 μg pireno L-1, 50 μg pireno L-1 para velocidade média de natação e distância linear nadada, e 1 μg pireno L-1 para incremento de peso. O aumento da atividade da GST após exposição a 500 μg fenantreno L-1 sugere um aumento dos gastos energéticos com os processos de biotransformação de fase 2, e esta alteração esteve associada a decréscimos na atividade locomotora, na habilidade de capturar presas, e também no crescimento. A exposição ao pireno também apresentou um padrão semelhante, com alterações detectadas em concentrações menores, indicando uma maior potência do pireno comparado ao fenantreno para induzir a GST, gerar hipoatividade locomotora e inibir o crescimento, parâmetro de maior relevância para o recrutamento da espécie. Estes resultados sugerem que o uso de jovens recém-nascidos de Poecilia vivipara como modelos ecotoxicológicos para a compreensão dos efeitos de contaminantes em parâmetros de diferentes níveis de organização biológica relacionados ao recrutamento de peixes é promissor.
Poecilia vivipara has a wide distribution pattern along the Brazilian coast, and its reproduction by viviparity enables the use of newborn in ecotoxicological studies to evaluate the potential toxicity of environmental contaminants. This study aimed to assess the lethal and sublethal effects on these early stages of life of the estuarine fish Poecilia vivipara after exposure to different concentrations of the PAHs phenanthrene and pyrene dissolved in water. The newborn were obtained from a breeding stock kept under controlled conditions, and exposed to phenanthrene concentrations of 10, 50, 200 and 500 μg L-1 and control for 7 days, and pyrene concentrations of 1, 10, 50 and 100 μg L-1 and control for 14 days. After exposure, the mortality rate was calculated, and the survivors were evaluated for the sublethal parameters glutathione S-transferase activity (GST), spontaneous swimming speed, prey capture rate and growth. Young individuals exposed to 500 μg phenanthrene L-1 exhibited 40% mortality, only detected in this concentration. Juveniles exposed to pyrene concentrations of 50 and 100 μg pyrene L-1 exhibited 44% and 33% mortality, respectively, and no mortality was detected in other tested concentrations. Regarding sublethal parameters, the lowest observed effect concentration (LOEC) for GST activity, average swimming speed, linear swimming distance and weight increase was equal to 500 μg phenanthrene L-1. Already for an exposition to pyrene the LOEC for GST activity was equal to 10 μg pyrene L-1, 50 μg pyrene L-1 for average swimming speed, and 1 μg pyrene L-1 for weight increase. The increase in GST activity after exposure to 500 μg phenanthrene L-1 suggests an increase in energy expenditure with the biotransformation processes of phase 2, and this change was associated with decreases in locomotor activity, the ability to catch prey, and also in growth. Exposure to pyrene also exhibited a similar pattern, with changes detected in lower concentrations, indicating a greater pyrene potency compared to phenanthrene to induce GST and to generate locomotor hypoactivity and inhibit growth, the most relevant parameter for the recruitment of the species. These results suggest the potential use of newborn young Poecilia vivipara as ecotoxicological models for understanding the effects of contaminants on parameters of distintic biological organization levels related to the recruitment of fish.
Los estilos APA, Harvard, Vancouver, ISO, etc.
8

Bloomer, Daniel John. "Sediment sorting in the gravel-sand transition along rivers : a field and modelling investigation". Thesis, University of Sheffield, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341852.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
9

Beasley, Steven Ari. "Expression of the Pasteurella haemolytica O-sialoglycoprotein endopeptidase as a GST fusion protein". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ33205.pdf.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
10

Santos, Stéphanie Piacenti dos. "Marcadores moleculares GST e CYP relacionados com fatores clínicos em câncer de mama". Faculdade de Medicina de São José do Rio Preto, 2016. http://hdl.handle.net/tede/420.

Texto completo
Resumen
Submitted by Suzana Dias (suzana.dias@famerp.br) on 2018-10-19T18:22:34Z No. of bitstreams: 1 StephaniePiacentidosSantos_dissert.pdf: 499357 bytes, checksum: e7f6872448bfb8c9bb786b4bd30f9c94 (MD5)
Made available in DSpace on 2018-10-19T18:22:34Z (GMT). No. of bitstreams: 1 StephaniePiacentidosSantos_dissert.pdf: 499357 bytes, checksum: e7f6872448bfb8c9bb786b4bd30f9c94 (MD5) Previous issue date: 2016-11-08
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES
Breast cancer is a leading cause of death in women worldwide. The etiology of this disease is multifactorial, including factors such as habits and lifestyle, hormonal, environmental and genetic. The xenobiotic metabolism contribute to the development of breast carcinoma and polymorphisms in genes encoding enzymes in this pathway, such as GST (GSTM1 and GSTT1) and CYPs (CYP1A1*2A and CYP1A1*2C) have been associated to breast cancer. Objectives: To investigate the influence of the GSTM1, GSTT1, CYP1A1*2A and CYP1A1*2C polymorphisms at the risk for developing breast cancer; to evaluate the association of polymorphisms and risk factors (age, smoking, alcohol, clinical features), tumor clinical and histopathologic features in breast cancer. Methods: This case-control study included 752 women, 219 patients and 533 controls. Molecular analysis were performed by PCR-multiplex (GSTM1 null and GSTT1 null), PCR-RFLP (CYP1A1*2A) and real-time PCR (CYP1A1*2C). For the statistical analysis, the MINITAB 16.0 (Multiple Logistic Regression Test), SNPstats (Inheritance Model tests) and BioEstat 5.0 (Hardy-Weinberg test) tests were used. Results: Women with old age and the alcohol consumption had increased risk for developing breast cancer. Women with breast cancer had slightly higher frequency (51%) of the GSTM1 null genotype than women without cancer (49%), however this difference was not significant statistically. GSTT1 null genotype was also not associated with breast cancer. CYP1A1*2A polymorphism was associated with the risk for breast cancer and CYP1A1*2C polymorphism was more frequent in tumors with no distant metastases. Conclusions: Women with age advanced and who drink alcohol present increased risk for developing breast cancer. CYP1A1*2A polymorphism is associated with breast cancer and CYP1A1*2C polymorphism is related to women with no distant metastases. The polymorphisms of the GSTM1 and GSTT1 genes are not associated with the development of breast cancer.
O câncer de mama é uma das principais causas de morte em mulheres no mundo. A etiologia desta doença é multifatorial e inclui fatores como hábitos, estilo de vida, hormonais, ambientais e genéticos. O metabolismo de xenobióticos contribui para o desenvolvimento do carcinoma mamário, e polimorfismos nos genes que codificam enzimas desta via, tais como GSTs (GSTM1 e GSTT1) e CYPs (CYP1A1*2A e CYP1A1*2C) têm sido associados ao câncer de mama. Objetivos: Investigar a influência dos polimorfismos GSTM1, GSTT1, CYP1A1*2A e CYP1A1*2C no risco de desenvolvimento de câncer de mama; avaliar a associação dos polimorfismos e fatores de risco (idade, fumo, álcool, características clínicas) no câncer de mama, assim como características clínicas e histopatológicas do tumor. Casuística e Métodos: O presente estudo caso-controle incluiu 752 mulheres, 219 pacientes e 533 controles. Para análise molecular foram realizadas as técnicas de PCR-Multiplex (GSTM1 e GSTT1), PCR-RFLP (CYP1A1*2A) e PCR em tempo real (CYP1A1*2C). Para a análise estatística foram utilizados os programas MINITAB 16.0 (teste de Regressão Logística Múltipla), SNPstats (testes de Modelos de Herança) e BioEstat 5.0 (teste de Equílibrio de Hardy-Weinberg). Resultados: Mulheres com idade avançada e com o hábito etilista apresentaram risco aumentado para o desenvolvimento de câncer de mama. Mulheres com carcinoma mamário apresentaram frequência discretamente maior (51%) do genótipo nulo GSTM1 em relação a mulheres sem câncer (49%), no entanto essa diferença não foi estatisticamente significante. O genótipo nulo de GSTT1 também não foi associado ao câncer de mama. O polimorfismo CYP1A1*2A foi associado ao risco para câncer de mama e o polimorfismo CYP1A1*2C foi mais frequente em tumores com ausência de metástase à distância. Conclusões: Mulheres com idade avançada e que ingerem bebida alcoólica apresentam risco aumentado para desenvolver câncer de mama. O polimorfismo CYP1A1*2A está associado ao câncer de mama e o polimorfismo CYP1A1*2C está relacionado às mulheres com ausência de metástase à distância. Os polimorfismos dos genes GSTM1 e GSTT1 não apresentam associação com o desenvolvimento do câncer de mama.
Los estilos APA, Harvard, Vancouver, ISO, etc.

Libros sobre el tema "GST"

1

Subramaniam, Arjunan. Understanding GST. Petaling Jaya, Selangor Darul Ehsan: LexisNexis, 2014.

Buscar texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
2

Revenue, New Zealand Inland. GST guide: A guide to working with GST. [Wellington, N.Z.?]: Inland Revenue, 2000.

Buscar texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
3

McCouat, Philip. GST survival guide. Sydney, NSW: CCH Australia, 1999.

Buscar texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
4

Allan, Taitz y Millar W. Jack, eds. GST & commodity tax. Don Mills, Ont: R. DeBoo, 1989.

Buscar texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
5

Peter, Hill. GST business essentials. Pyrmont, N.S.W: Australian Tax Practice, 1999.

Buscar texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
6

Ken, Fehily, ed. Handy GST guide. Sydney, NSW: CCH Australia, 1998.

Buscar texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
7

Douglass, Ray. GST: The answers : the plain English guide to the GST. [Kenmore, Qld: InTax, 1999.

Buscar texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
8

McKenzie, Alastair. GST, a practical guide. Beach Haven, Auckland: CCH New Zealand, 1994.

Buscar texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
9

McKenzie, Alastair. GST, a practical guide. 7a ed. Auckland: CCH New Zealand, 2002.

Buscar texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
10

Naban, D. P. CCH GST case summaries. Kuala Lumpur: Commerce Clearing House (Malaysia) Sbn Bhd, 2014.

Buscar texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.

Capítulos de libros sobre el tema "GST"

1

Meigs, Thomas E., Alex Lyakhovich, Hoon Shim, Ching-Kang Chen, Denis J. Dupré, Terence E. Hébert, Joe B. Blumer et al. "GST". En Encyclopedia of Signaling Molecules, 831. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100577.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
2

Leister, Dario y Claudio Varotto. "GST-PRIME". En PCR Primer Design, 141–57. Totowa, NJ: Humana Press, 2007. http://dx.doi.org/10.1007/978-1-59745-528-2_7.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
3

Krever, Richard y Jonathan Teoh. "GST and Insurance: Australia". En VAT and Financial Services, 319–35. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-3465-7_17.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
4

Koh, Soo How y Rushan Lee. "GST and Insurance: Singapore". En VAT and Financial Services, 365–72. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-3465-7_19.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
5

Smitha, E. S., S. Sendhilkumar y G. S. Mahalaksmi. "Measuring Social Sarcasm on GST". En New Trends in Computational Vision and Bio-inspired Computing, 1479–86. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-41862-5_152.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
6

Mittal, Abhinav, Puneet Agrawal y Shuchi Agrawal. "Tax Review—Indirect Taxes—GST". En Management for Professionals, 123–66. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-2019-6_8.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
7

Madan, Amogh, Ridhima Arora y Nihar Ranjan Roy. "Sentiment Analysis of Indians on GST". En Data Science and Analytics, 568–75. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-8527-7_47.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
8

Ergin, Ahmet Bahadir, Amir H. Hamrahian, A. Laurence Kennedy y Manjula K. Gupta. "Glucagon Stimulation Test for GHD (GST)". En The Cleveland Clinic Manual of Dynamic Endocrine Testing, 43–46. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-13048-4_11.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
9

Pfeiffer, Sebastian. "A VAT/GST Perspective on Crowdfunding". En VAT and Financial Services, 223–55. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-3465-7_14.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
10

Koyan, Philipp y Jens Tronicke. "The gradient structure tensor (GST): an efficient tool to analyze 3D GPR data for archaeological prospection". En Advances in On- and Offshore Archaeological Prospection, 423–25. Kiel: Universitätsverlag Kiel | Kiel University Publishing, 2023. http://dx.doi.org/10.38072/978-3-928794-83-1/p86.

Texto completo
Resumen
We present GPR data across remains in a Palace Garden at Paretz (Germany). We use the GST to highlight archaeological structures in the GPR data. We outline the flexibility and time-efficiency of a GST-based analysis strategy.
Los estilos APA, Harvard, Vancouver, ISO, etc.

Actas de conferencias sobre el tema "GST"

1

Remali, Azrinawati Mohd. "Problems In Gst Implementation And Gst Withdrawal Of Malaysian Smes". En 9th International Economics and Business Management Conference. European Publisher, 2020. http://dx.doi.org/10.15405/epsbs.2020.12.05.7.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
2

Fang, Zhuoran, Jiajiu Zheng, Peipeng XU y Arka Majumdar. "GST integrated silicon photonics". En Active Photonic Platforms XI, editado por Ganapathi S. Subramania y Stavroula Foteinopoulou. SPIE, 2019. http://dx.doi.org/10.1117/12.2525258.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
3

Edwards, A. H., A. C. Pineda y P. A. Schultz. "Roles of Oxygen in Crystalline GST and at the GST/TiAlN Interface". En 2007 Non-Volatile Memory Technology Symposium. IEEE, 2007. http://dx.doi.org/10.1109/nvmt.2007.4389942.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
4

Das, Sourav y Anup Kumar Kolya. "Sense GST: Text mining & sentiment analysis of GST tweets by Naive Bayes algorithm". En 2017 Third International Conference on Research in Computational Intelligence and Communication Networks (ICRCICN). IEEE, 2017. http://dx.doi.org/10.1109/icrcicn.2017.8234513.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
5

Choi, Chulsoo, Jangwoon Sung y Byoungho Lee. "All-optical multilevel switching of GST metasurface". En Frontiers in Optics. Washington, D.C.: OSA, 2020. http://dx.doi.org/10.1364/fio.2020.fm7e.8.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
6

Kuhlmann, Martin y Keshab K. Parhi. "Power comparison of SRT and GST dividers". En SPIE's International Symposium on Optical Science, Engineering, and Instrumentation, editado por Franklin T. Luk. SPIE, 1998. http://dx.doi.org/10.1117/12.325717.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
7

Tomar, Nandini, Ritesh Srivastava y J. K. Verma. "Analysing Public Sentiment on GST Implementation in India". En 2018 International Conference on Computing, Power and Communication Technologies (GUCON). IEEE, 2018. http://dx.doi.org/10.1109/gucon.2018.8675016.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
8

Huo, Z., X. Wang, W. Chen, H. Zhao y X. Liu. "One GST-Based High-Resolution Structural Curvature Estimation". En 82nd EAGE Annual Conference & Exhibition. European Association of Geoscientists & Engineers, 2020. http://dx.doi.org/10.3997/2214-4609.202010641.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
9

Ayres, Constância. "Molecular evolution of GST members in culicid vectors". En 2016 International Congress of Entomology. Entomological Society of America, 2016. http://dx.doi.org/10.1603/ice.2016.118271.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
10

Tibolla, O., Denis Bastieri y Riccardo Rando. "H.E.S.S. unidentified sources: how can Fermi GST help?" En SCIENCE WITH THE NEW GENERATION OF HIGH ENERGY GAMMA-RAY EXPERIMENTS: Proceedings of the 6th Edition: Bridging the Gap Between GeV and TeV. AIP, 2009. http://dx.doi.org/10.1063/1.3125784.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.

Informes sobre el tema "GST"

1

Mukherje, Sacchidananda. GST still searching for stability in India. East Asia Forum, mayo de 2019. http://dx.doi.org/10.59425/eabc.1557525629.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
2

Kumar, Anand. DiF - FiX Get Your Gut Back. Office of Scientific and Technical Information (OSTI), marzo de 2018. http://dx.doi.org/10.2172/1423993.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
3

Patil, Bhimanagouda S., Ron Porat, G. K. Jayaprakasha y K. N. C. Murthy. Optimization of Postharvest Storage Conditions to Maintain Fruit Quality and Health Maintaining Properties of Grapefruit. United States Department of Agriculture, enero de 2010. http://dx.doi.org/10.32747/2010.7613879.bard.

Texto completo
Resumen
Antioxidant activity of fruits is gaining wide interest among consumers due to its importance in counteracting oxidative stress, free radicals and preventing DNA damage. Oxygen radical absorbance capacity (ORAC) assay is one of the commonly used assays to measure the antioxidant activity, which is based on hydrogen atom transfer mechanism. Furocoumarins present in grapefruit are reported to have antiproliferative activity, induce GST activity, inhibit biofilm formation and increase bioavailability of drugs. In the present project ORAC values were measured of Star Ruby grapefruit undergone ethylene degreening treatment, cold storage and temperature conditioning treatment, and modified atmosphere packaging which were stored at different temperatures for prolonged period. In addition, furocoumarins were quantified in Star Ruby grapefruits from cold storage and conditioning experiment conducted in Israel. Conditioning treatment is practiced prior cold storage to reduce chilling injury in grapefruits during cold storage for prolonged period. Levels of 6,7-dihyrdoxy bergamottin decreased during storage period in all three treatments.
Los estilos APA, Harvard, Vancouver, ISO, etc.
4

Melidis, Konstantin y Markus Gruber. Begleitende Evaluierung IWB/EFRE AT 2014-20. Leistungspaket 1: Prioritätsachse 1 – Forschung, technologische Entwicklung und Innovation. Endbericht. Convelop gmbh, febrero de 2022. http://dx.doi.org/10.22163/fteval.2022.582.

Texto completo
Resumen
Die Geschäftsstelle der Österreichischen Raumordnungskonferenz (ÖROK GSt.) hat als Verwaltungsbehörde des österreichischen IWB/EFRE -Programms die Durchführung einer begleitenden Evaluierung des Programms beauftragt, die mit Zuschlagserteilung der Bundesbeschaffung GmbH vom 07.12.2017 an ein Konsortium bestehend aus ÖIR, convelop, KMUFA, ÖAR, ÖGUT sowie Spatial Foresight ging. Die Evaluierung wird in mehreren Leistungspaketen bearbeitet, die sich im Wesentlichen auf die Prioritätsachsen des Programms beziehen, ergänzt um Evaluierungen zu den Bereichen „Governance“, „Kommunikation“ und „Querschnittsthemen“. Die gegenständliche Evaluierung ist ein Bestandteil dieser begleitenden Evaluierung und befasst sich im Kern mit den Maßnahmen der Priorität 1 „Stärkung der regionalen Wettbewerbsfähigkeit durch Forschung, technologische Entwicklung und Innovation“, ergänzt um die Maßnahme 15 „F&I in CO2-Reduktionstechnologien“ (P3) sowie die Maßnahmen 16 „F&T-Infrastruktur (Wien)“ und 17 „Innovationsdienstleistungen (Wien)“ (beide PA4). Mit 226,4 Mio. € decken die behandelten Maßnahmen 42% der EFRE-Mittel des Gesamtprogramms ab. Die Evaluierung zeichnet insgesamt ein überwiegend positives Bild der FTI-Förderung im EFRE, das es gilt, auch in Zukunft aufrechtzuerhalten. Die Empfehlungen der FTI-Evaluierung zielen vor allem auf eine noch klarere Konzeption und Darstellung von FTI-Maßnahmen mit grundsätzlich unterschiedlichen Wirkungslogiken und eine Weiterführung bestehender Bemühungen zur Harmonisierung regional unterschiedlicher Abwicklungsmodi innerhalb dieser Maßnahmen ab. Daneben sollte der Anspruch der Anwendungsorientierung im Lichte der stark wahrgenommenen Grundlagenorientierung in der Praxis reflektiert werden. Auch im Bereich der Datenerfassung und -qualitätsicherung wurden Ansatzpunkte für Verbesserungen aufgezeigt.
Los estilos APA, Harvard, Vancouver, ISO, etc.
5

Gershoni, Jonathan M., David E. Swayne, Tal Pupko, Shimon Perk, Alexander Panshin, Avishai Lublin y Natalia Golander. Discovery and reconstitution of cross-reactive vaccine targets for H5 and H9 avian influenza. United States Department of Agriculture, enero de 2015. http://dx.doi.org/10.32747/2015.7699854.bard.

Texto completo
Resumen
Research objectives: Identification of highly conserved B-cell epitopes common to either H5 or H9 subtypes of AI Reconstruction of conserved epitopes from (1) as recombinantimmunogens, and testing their suitability to be used as universal vaccine components by measuring their binding to Influenza vaccinated sera of birds Vaccination of chickens with reconstituted epitopes and evaluation of successful vaccination, clinical protection and viral replication Development of a platform to investigate the dynamics of immune response towards infection or an epitope based vaccine Estimate our ability to focus the immune response towards an epitope-based vaccine using the tool we have developed in (D) Summary: This study is a multi-disciplinary study of four-way collaboration; The SERPL, USDA, Kimron-Israel, and two groups at TAU with the purpose of evaluating the production and implementation of epitope based vaccines against avian influenza (AI). Systematic analysis of the influenza viral spike led to the production of a highly conserved epitope situated at the hinge of the HA antigen designated “cluster 300” (c300). This epitope consists of a total of 31 residues and was initially expressed as a fusion protein of the Protein 8 major protein of the bacteriophagefd. Two versions of the c300 were produced to correspond to the H5 and H9 antigens respectively as well as scrambled versions that were identical with regard to amino acid composition yet with varied linear sequence (these served as negative controls). The recombinantimmunogens were produced first as phage fusions and then subsequently as fusions with maltose binding protein (MBP) or glutathioneS-transferase (GST). The latter were used to immunize and boost chickens at SERPL and Kimron. Furthermore, vaccinated and control chickens were challenged with concordant influenza strains at Kimron and SEPRL. Polyclonal sera were obtained for further analyses at TAU and computational bioinformatics analyses in collaboration with Prof. Pupko. Moreover, the degree of protection afforded by the vaccination was determined. Unfortunately, no protection could be demonstrated. In parallel to the main theme of the study, the TAU team (Gershoni and Pupko) designed and developed a novel methodology for the systematic analysis of the antibody composition of polyclonal sera (Deep Panning) which is essential for the analyses of the humoral response towards vaccination and challenge. Deep Panning is currently being used to monitor the polyclonal sera derived from the vaccination studies conducted at the SEPRL and Kimron.
Los estilos APA, Harvard, Vancouver, ISO, etc.
6

Josefsson, S. y N. Williams. Using Generic Security Service Application Program Interface (GSS-API) Mechanisms in Simple Authentication and Security Layer (SASL): The GS2 Mechanism Family. RFC Editor, julio de 2010. http://dx.doi.org/10.17487/rfc5801.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
7

Popov, V., I. Kurepkin y S. Leontiev. Additional Cryptographic Algorithms for Use with GOST 28147-89, GOST R 34.10-94, GOST R 34.10-2001, and GOST R 34.11-94 Algorithms. RFC Editor, enero de 2006. http://dx.doi.org/10.17487/rfc4357.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
8

Roberts, Randy S., Paul A. Pope, Ming Jiang, Timothy G. Trucano, Cecilia R. Aragon, Kevin Ni, Thomas Wei, Lawrence K. Chilton y Alan Bakel. GSV Annotated Bibliography. Office of Scientific and Technical Information (OSTI), junio de 2011. http://dx.doi.org/10.2172/1118027.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
9

Roberts, Randy S., Paul A. Pope, Ming Jiang, Timothy G. Trucano, Cecilia R. Aragon, Kevin Ni, Thomas Wei, Lawrence K. Chilton y Alan Bakel. GSV Annotated Bibliography. Office of Scientific and Technical Information (OSTI), septiembre de 2010. http://dx.doi.org/10.2172/1124861.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
10

Costello, Dr Anna, Dr Satinder Dalay, Dr Andrew Hartle, Dr Ben Fox, Dr JP Lomas, Elizabeth H. Shewry, Dr Emma Plunkett, Dr Sarah Gibb y Nicola Barber. Trainee (GAT) handbook. The Association of Anaesthetists of Great Britain and Ireland, 2017. http://dx.doi.org/10.21466/g.gh.2017.

Texto completo
Los estilos APA, Harvard, Vancouver, ISO, etc.
Ofrecemos descuentos en todos los planes premium para autores cuyas obras están incluidas en selecciones literarias temáticas. ¡Contáctenos para obtener un código promocional único!

Pasar a la bibliografía