Artículos de revistas sobre el tema "GPCR"
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Vidad, Ashley Ryan, Stephen Macaspac y Ho Leung Ng. "Locating ligand binding sites in G-protein coupled receptors using combined information from docking and sequence conservation". PeerJ 9 (24 de septiembre de 2021): e12219. http://dx.doi.org/10.7717/peerj.12219.
Texto completoGonzález-Guede, Irene, María López-Ramos, Luis Rodríguez-Rodríguez, Lydia Abasolo, Arkaitz Mucientes y Benjamín Fernández-Gutiérrez. "Dysregulation of Glypicans and Notum in Osteoarthritis: Plasma Levels, Bone Marrow Mesenchymal Stromal Cells and Osteoblasts". Cells 13, n.º 10 (16 de mayo de 2024): 852. http://dx.doi.org/10.3390/cells13100852.
Texto completoTany, Ryosuke, Yuhei Goto, Yohei Kondo y Kazuhiro Aoki. "Quantitative live-cell imaging of GPCR downstream signaling dynamics". Biochemical Journal 479, n.º 8 (21 de abril de 2022): 883–900. http://dx.doi.org/10.1042/bcj20220021.
Texto completoBaidya, Mithu, Punita Kumari, Hemlata Dwivedi-Agnihotri, Shubhi Pandey, Badr Sokrat, Silvia Sposini, Madhu Chaturvedi et al. "Genetically encoded intrabody sensors report the interaction and trafficking of β-arrestin 1 upon activation of G-protein–coupled receptors". Journal of Biological Chemistry 295, n.º 30 (21 de mayo de 2020): 10153–67. http://dx.doi.org/10.1074/jbc.ra120.013470.
Texto completoChattopadhyay, Amitabha. "GPCRs: Lipid-Dependent Membrane Receptors That Act as Drug Targets". Advances in Biology 2014 (2 de octubre de 2014): 1–12. http://dx.doi.org/10.1155/2014/143023.
Texto completoLiu, Samuel, Preston J. Anderson, Sudarshan Rajagopal, Robert J. Lefkowitz y Howard A. Rockman. "G Protein-Coupled Receptors: A Century of Research and Discovery". Circulation Research 135, n.º 1 (21 de junio de 2024): 174–97. http://dx.doi.org/10.1161/circresaha.124.323067.
Texto completoKapolka, Nicholas J., Jacob B. Rowe, Geoffrey J. Taghon, William M. Morgan, Corin R. O’Shea y Daniel G. Isom. "Proton-gated coincidence detection is a common feature of GPCR signaling". Proceedings of the National Academy of Sciences 118, n.º 28 (6 de julio de 2021): e2100171118. http://dx.doi.org/10.1073/pnas.2100171118.
Texto completoSouthern, Craig, Jennifer M. Cook, Zaynab Neetoo-Isseljee, Debra L. Taylor, Catherine A. Kettleborough, Andy Merritt, Daniel L. Bassoni et al. "Screening β-Arrestin Recruitment for the Identification of Natural Ligands for Orphan G-Protein–Coupled Receptors". Journal of Biomolecular Screening 18, n.º 5 (8 de febrero de 2013): 599–609. http://dx.doi.org/10.1177/1087057113475480.
Texto completoJu, Man-Seok y Sang Taek Jung. "Antigen Design for Successful Isolation of Highly Challenging Therapeutic Anti-GPCR Antibodies". International Journal of Molecular Sciences 21, n.º 21 (3 de noviembre de 2020): 8240. http://dx.doi.org/10.3390/ijms21218240.
Texto completoYan, Huan, Jingling Zhang, Kam-Tong Leung, Kwok-Wai Lo, Jun Yu, Ka-Fai To y Wei Kang. "An Update of G-Protein-Coupled Receptor Signaling and Its Deregulation in Gastric Carcinogenesis". Cancers 15, n.º 3 (25 de enero de 2023): 736. http://dx.doi.org/10.3390/cancers15030736.
Texto completoTu, Shisheng, Rui Xu, Mengen Wang, Xi Xie, Chenchang Bao y Dongfa Zhu. "Identification and characterization of expression profiles of neuropeptides and their GPCRs in the swimming crab, Portunus trituberculatus". PeerJ 9 (15 de septiembre de 2021): e12179. http://dx.doi.org/10.7717/peerj.12179.
Texto completoTakahashi, Masaki, Ryo Amano, Michiru Ozawa, Anna Martinez, Kazumasa Akita y Yoshikazu Nakamura. "Nucleic acid ligands act as a PAM and agonist depending on the intrinsic ligand binding state of P2RY2". Proceedings of the National Academy of Sciences 118, n.º 18 (28 de abril de 2021): e2019497118. http://dx.doi.org/10.1073/pnas.2019497118.
Texto completoLazim, Raudah, Donghyuk Suh, Jai Woo Lee, Thi Ngoc Lan Vu, Sanghee Yoon y Sun Choi. "Structural Characterization of Receptor–Receptor Interactions in the Allosteric Modulation of G Protein-Coupled Receptor (GPCR) Dimers". International Journal of Molecular Sciences 22, n.º 6 (22 de marzo de 2021): 3241. http://dx.doi.org/10.3390/ijms22063241.
Texto completoRahman, Md Mominur, Md Rezaul Islam, Sadia Afsana Mim, Nasrin Sultana, Dinesh Kumar Chellappan, Kamal Dua, Mohammad Amjad Kamal, Rohit Sharma y Talha Bin Emran. "Insights into the Promising Prospect of G Protein and GPCR-Mediated Signaling in Neuropathophysiology and Its Therapeutic Regulation". Oxidative Medicine and Cellular Longevity 2022 (21 de septiembre de 2022): 1–22. http://dx.doi.org/10.1155/2022/8425640.
Texto completoLuttrell, Louis M. y Robert J. Lefkowitz. "The role of β-arrestins in the termination and transduction of G-protein-coupled receptor signals". Journal of Cell Science 115, n.º 3 (1 de febrero de 2002): 455–65. http://dx.doi.org/10.1242/jcs.115.3.455.
Texto completoBerger, Miles, David W. Scheel, Hector Macias, Takeshi Miyatsuka, Hail Kim, Phuong Hoang, Greg M. Ku et al. "Gαi/o-coupled receptor signaling restricts pancreatic β-cell expansion". Proceedings of the National Academy of Sciences 112, n.º 9 (18 de febrero de 2015): 2888–93. http://dx.doi.org/10.1073/pnas.1319378112.
Texto completoWang, Xiaoyan, Ning Sui, Dandan Hu, Ziwei Zhang y Tiejun Bing. "Abstract 4712: GPCR panel establishment and application in drug discovery". Cancer Research 84, n.º 6_Supplement (22 de marzo de 2024): 4712. http://dx.doi.org/10.1158/1538-7445.am2024-4712.
Texto completoKapolka, N. J., G. J. Taghon, J. B. Rowe, W. M. Morgan, J. F. Enten, N. A. Lambert y D. G. Isom. "DCyFIR: a high-throughput CRISPR platform for multiplexed G protein-coupled receptor profiling and ligand discovery". Proceedings of the National Academy of Sciences 117, n.º 23 (20 de mayo de 2020): 13117–26. http://dx.doi.org/10.1073/pnas.2000430117.
Texto completoPFLEGER, Kevin D. G. y Karin A. EIDNE. "Monitoring the formation of dynamic G-protein-coupled receptor–protein complexes in living cells". Biochemical Journal 385, n.º 3 (24 de enero de 2005): 625–37. http://dx.doi.org/10.1042/bj20041361.
Texto completoWakeling, Madeleine N., Douglas J. Roy, Anthony A. Nash y James P. Stewart. "Characterization of the murine gammaherpesvirus 68 ORF74 product: a novel oncogenic G protein-coupled receptor". Journal of General Virology 82, n.º 5 (1 de mayo de 2001): 1187–97. http://dx.doi.org/10.1099/0022-1317-82-5-1187.
Texto completoParadis, Justine S., Stevenson Ly, Élodie Blondel-Tepaz, Jacob A. Galan, Alexandre Beautrait, Mark G. H. Scott, Hervé Enslen, Stefano Marullo, Philippe P. Roux y Michel Bouvier. "Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression". Proceedings of the National Academy of Sciences 112, n.º 37 (31 de agosto de 2015): E5160—E5168. http://dx.doi.org/10.1073/pnas.1508836112.
Texto completoBarwell, James, Mark Wheatley, Alex C. Conner, Bruck Taddese, Shabana Vohra, Christopher A. Reynolds y David R. Poyner. "The activation of the CGRP receptor". Biochemical Society Transactions 41, n.º 1 (29 de enero de 2013): 180–84. http://dx.doi.org/10.1042/bst20120251.
Texto completoZheng, Chen, Liana D. Weinstein, Kevin K. Nguyen, Abhijeet Grewal, Eugenia V. Gurevich y Vsevolod V. Gurevich. "GPCR Binding and JNK3 Activation by Arrestin-3 Have Different Structural Requirements". Cells 12, n.º 12 (6 de junio de 2023): 1563. http://dx.doi.org/10.3390/cells12121563.
Texto completoEllisdon, Andrew M. y Michelle L. Halls. "Compartmentalization of GPCR signalling controls unique cellular responses". Biochemical Society Transactions 44, n.º 2 (11 de abril de 2016): 562–67. http://dx.doi.org/10.1042/bst20150236.
Texto completoLorenzen, Emily, Tea Dodig-Crnković, Ilana B. Kotliar, Elisa Pin, Emilie Ceraudo, Roger D. Vaughan, Mathias Uhlèn, Thomas Huber, Jochen M. Schwenk y Thomas P. Sakmar. "Multiplexed analysis of the secretin-like GPCR-RAMP interactome". Science Advances 5, n.º 9 (septiembre de 2019): eaaw2778. http://dx.doi.org/10.1126/sciadv.aaw2778.
Texto completoZhao, Xiaoning, Adrie Jones, Keith R. Olson, Kun Peng, Tom Wehrman, Adam Park, Rommel Mallari, Danilo Nebalasca, Stephen W. Young y Shou-Hua Xiao. "A Homogeneous Enzyme Fragment Complementation-Based β-Arrestin Translocation Assay for High-Throughput Screening of G-Protein-Coupled Receptors". Journal of Biomolecular Screening 13, n.º 8 (25 de julio de 2008): 737–47. http://dx.doi.org/10.1177/1087057108321531.
Texto completoSutkeviciute, Ieva y Jean-Pierre Vilardaga. "Structural insights into emergent signaling modes of G protein–coupled receptors". Journal of Biological Chemistry 295, n.º 33 (22 de junio de 2020): 11626–42. http://dx.doi.org/10.1074/jbc.rev120.009348.
Texto completoSato. "Conserved 2nd Residue of Helix 8 of GPCR May Confer the Subclass-Characteristic and Distinct Roles through a Rapid Initial Interaction with Specific G Proteins". International Journal of Molecular Sciences 20, n.º 7 (9 de abril de 2019): 1752. http://dx.doi.org/10.3390/ijms20071752.
Texto completoRivero-Müller, Adolfo, Yen-Yin Chou, Inhae Ji, Svetlana Lajic, Aylin C. Hanyaloglu, Kim Jonas, Nafis Rahman, Tae H. Ji y Ilpo Huhtaniemi. "Rescue of defective G protein–coupled receptor function in vivo by intermolecular cooperation". Proceedings of the National Academy of Sciences 107, n.º 5 (11 de enero de 2010): 2319–24. http://dx.doi.org/10.1073/pnas.0906695106.
Texto completoChini, Bice y Marco Parenti. "G-protein-coupled receptors, cholesterol and palmitoylation: facts about fats". Journal of Molecular Endocrinology 42, n.º 5 (8 de enero de 2009): 371–79. http://dx.doi.org/10.1677/jme-08-0114.
Texto completoZhu, Siyu, Meixian Wu, Ziwei Huang y Jing An. "Trends in application of advancing computational approaches in GPCR ligand discovery". Experimental Biology and Medicine 246, n.º 9 (27 de febrero de 2021): 1011–24. http://dx.doi.org/10.1177/1535370221993422.
Texto completoCroft, Wayne, Claire Hill, Eilish McCann, Michael Bond, Manuel Esparza-Franco, Jeannette Bennett, David Rand, John Davey y Graham Ladds. "A Physiologically Required G Protein-coupled Receptor (GPCR)-Regulator of G Protein Signaling (RGS) Interaction That Compartmentalizes RGS Activity". Journal of Biological Chemistry 288, n.º 38 (30 de julio de 2013): 27327–42. http://dx.doi.org/10.1074/jbc.m113.497826.
Texto completoAgbedanu, P., No author No author, M. Brewer, No author No author, T. Day, M. Kimber, K. Anderson, S. Rasmussen y M. Carlson. "Involvement of a putative intercellular signal-recognizing G protein-coupled receptor in the engulfment of Salmonella by the protozoan Tetrahymena". Open Veterinary Journal 5, n.º 2 (2013): 69. http://dx.doi.org/10.5455/ovj.2013.v3.i2.p69.
Texto completoGupte, Tejas M., Rabia U. Malik, Ruth F. Sommese, Michael Ritt y Sivaraj Sivaramakrishnan. "Priming GPCR signaling through the synergistic effect of two G proteins". Proceedings of the National Academy of Sciences 114, n.º 14 (21 de marzo de 2017): 3756–61. http://dx.doi.org/10.1073/pnas.1617232114.
Texto completoJiang, Yuhong, Xin Zhuo y Canquan Mao. "G Protein-coupled Receptors in Cancer Stem Cells". Current Pharmaceutical Design 26, n.º 17 (7 de junio de 2020): 1952–63. http://dx.doi.org/10.2174/1381612826666200305130009.
Texto completoVenkatakrishnan, A. J., Anthony K. Ma, Rasmus Fonseca, Naomi R. Latorraca, Brendan Kelly, Robin M. Betz, Chaitanya Asawa, Brian K. Kobilka y Ron O. Dror. "Diverse GPCRs exhibit conserved water networks for stabilization and activation". Proceedings of the National Academy of Sciences 116, n.º 8 (6 de febrero de 2019): 3288–93. http://dx.doi.org/10.1073/pnas.1809251116.
Texto completoZheng, Liang-Hong, Chang-He Wang, Shu-Jiang Shang, Xiao-Yu Zhang, Ye-Shi Wang, Qi-Hui Wu, Mei-Qin Hu et al. "Real-time endocytosis imaging as a rapid assay of ligand-GPCR binding in single cells". American Journal of Physiology-Cell Physiology 305, n.º 7 (1 de octubre de 2013): C751—C760. http://dx.doi.org/10.1152/ajpcell.00335.2012.
Texto completoCheng, Han, Calli M. Lear-Rooney, Lisa Johansen, Elizabeth Varhegyi, Zheng W. Chen, Gene G. Olinger y Lijun Rong. "Inhibition of Ebola and Marburg Virus Entry by G Protein-Coupled Receptor Antagonists". Journal of Virology 89, n.º 19 (22 de julio de 2015): 9932–38. http://dx.doi.org/10.1128/jvi.01337-15.
Texto completoWang, Lei, Lu Zhu, Jaroslawna Meister, Derek B. J. Bone, Sai P. Pydi, Mario Rossi y Jürgen Wess. "Use of DREADD Technology to Identify Novel Targets for Antidiabetic Drugs". Annual Review of Pharmacology and Toxicology 61, n.º 1 (6 de enero de 2021): 421–40. http://dx.doi.org/10.1146/annurev-pharmtox-030220-121042.
Texto completoHou, Tianling, Yuemin Bian, Terence McGuire y Xiang-Qun Xie. "Integrated Multi-Class Classification and Prediction of GPCR Allosteric Modulators by Machine Learning Intelligence". Biomolecules 11, n.º 6 (11 de junio de 2021): 870. http://dx.doi.org/10.3390/biom11060870.
Texto completoWouters, Vasudevan, Crans, Saini y Stove. "Luminescence- and Fluorescence-Based Complementation Assays to Screen for GPCR Oligomerization: Current State of the Art". International Journal of Molecular Sciences 20, n.º 12 (17 de junio de 2019): 2958. http://dx.doi.org/10.3390/ijms20122958.
Texto completoSuteau, Valentine, Mathilde Munier, Rym Ben Boubaker, Méline Wery, Daniel Henrion, Patrice Rodien y Claire Briet. "Identification of Dysregulated Expression of G Protein Coupled Receptors in Endocrine Tumors by Bioinformatics Analysis: Potential Drug Targets?" Cells 11, n.º 4 (17 de febrero de 2022): 703. http://dx.doi.org/10.3390/cells11040703.
Texto completoRozenfeld, Raphael y Lakshmi A. Devi. "Exploring a role for heteromerization in GPCR signalling specificity". Biochemical Journal 433, n.º 1 (15 de diciembre de 2010): 11–18. http://dx.doi.org/10.1042/bj20100458.
Texto completoWu, Na, Agnieszka M. Olechwier, Cyrill Brunner, Patricia C. Edwards, Ching-Ju Tsai, Christopher G. Tate, Gebhard F. X. Schertler et al. "High-mass MALDI-MS unravels ligand-mediated G protein–coupling selectivity to GPCRs". Proceedings of the National Academy of Sciences 118, n.º 31 (29 de julio de 2021): e2024146118. http://dx.doi.org/10.1073/pnas.2024146118.
Texto completoZhang, Yinjie, Boyang Jason Wu, Xiaolan Yu, Ping Luo, Hao Ye, Yan Yu, Wei Han y Jingjing Li. "Development of an Antigen-Antibody Co-Display System for Detecting Interaction of G-Protein-Coupled Receptors and Single-Chain Variable Fragments". International Journal of Molecular Sciences 22, n.º 9 (29 de abril de 2021): 4711. http://dx.doi.org/10.3390/ijms22094711.
Texto completoKwon, Yong-Jun, Weontae Lee, Auguste Genovesio y Neil Emans. "A High-Content Subtractive Screen for Selecting Small Molecules Affecting Internalization of GPCRs". Journal of Biomolecular Screening 17, n.º 3 (15 de noviembre de 2011): 379–85. http://dx.doi.org/10.1177/1087057111427347.
Texto completoOsmond, Ronald I. W., Antony Sheehan, Romana Borowicz, Emma Barnett, Georgina Harvey, Cheryl Turner, Andrea Brown, Michael F. Crouch y Anthony R. Dyer. "GPCR Screening via ERK 1/2: A Novel Platform for Screening G Protein–Coupled Receptors". Journal of Biomolecular Screening 10, n.º 7 (16 de septiembre de 2005): 730–37. http://dx.doi.org/10.1177/1087057105277968.
Texto completoJastrzebska, Beata, Yaroslav Tsybovsky y Krzysztof Palczewski. "Complexes between photoactivated rhodopsin and transducin: progress and questions". Biochemical Journal 428, n.º 1 (28 de abril de 2010): 1–10. http://dx.doi.org/10.1042/bj20100270.
Texto completoNoonan, Theresa, Katrin Denzinger, Valerij Talagayev, Yu Chen, Kristina Puls, Clemens Alexander Wolf, Sijie Liu, Trung Ngoc Nguyen y Gerhard Wolber. "Mind the Gap—Deciphering GPCR Pharmacology Using 3D Pharmacophores and Artificial Intelligence". Pharmaceuticals 15, n.º 11 (22 de octubre de 2022): 1304. http://dx.doi.org/10.3390/ph15111304.
Texto completoKotliar, Ilana B., Annika Bendes, Leo Dahl, Yuanhuang Chen, Marcus Saarinen, Emilie Ceraudo, Tea Dodig-Crnković et al. "Multiplexed mapping of the interactome of GPCRs with receptor activity–modifying proteins". Science Advances 10, n.º 31 (2 de agosto de 2024). http://dx.doi.org/10.1126/sciadv.ado9959.
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