Literatura académica sobre el tema "GENE DELIVERY APPLICATIONS"
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Artículos de revistas sobre el tema "GENE DELIVERY APPLICATIONS"
Huang, Rih-Yang, Zhuo-Hao Liu, Wei-Han Weng y Chien-Wen Chang. "Magnetic nanocomplexes for gene delivery applications". Journal of Materials Chemistry B 9, n.º 21 (2021): 4267–86. http://dx.doi.org/10.1039/d0tb02713h.
Texto completoChen, Chih-Kuang, Ping-Kuan Huang, Wing-Cheung Law, Chia-Hui Chu, Nai-Tzu Chen y Leu-Wei Lo. "Biodegradable Polymers for Gene-Delivery Applications". International Journal of Nanomedicine Volume 15 (marzo de 2020): 2131–50. http://dx.doi.org/10.2147/ijn.s222419.
Texto completoKatz, M. G., A. S. Fargnoli, L. A. Pritchette y C. R. Bridges. "Gene delivery technologies for cardiac applications". Gene Therapy 19, n.º 6 (15 de marzo de 2012): 659–69. http://dx.doi.org/10.1038/gt.2012.11.
Texto completoMakkonen, Kaisa-Emilia, Kari Airenne y Seppo Ylä-Herttulala. "Baculovirus-mediated Gene Delivery and RNAi Applications". Viruses 7, n.º 4 (22 de abril de 2015): 2099–125. http://dx.doi.org/10.3390/v7042099.
Texto completoSuda, Takeshi y Dexi Liu. "Hydrodynamic Gene Delivery: Its Principles and Applications". Molecular Therapy 15, n.º 12 (diciembre de 2007): 2063–69. http://dx.doi.org/10.1038/sj.mt.6300314.
Texto completoYin, Feng, Bobo Gu, Yining Lin, Nishtha Panwar, Swee Chuan Tjin, Junle Qu, Shu Ping Lau y Ken-Tye Yong. "Functionalized 2D nanomaterials for gene delivery applications". Coordination Chemistry Reviews 347 (septiembre de 2017): 77–97. http://dx.doi.org/10.1016/j.ccr.2017.06.024.
Texto completoRabiee, Navid, Shokooh Ahmadvand, Sepideh Ahmadi, Yousef Fatahi, Rassoul Dinarvand, Mojtaba Bagherzadeh, Mohammad Rabiee, Mohammadreza Tahriri, Lobat Tayebi y Michael R. Hamblin. "Carbosilane dendrimers: Drug and gene delivery applications". Journal of Drug Delivery Science and Technology 59 (octubre de 2020): 101879. http://dx.doi.org/10.1016/j.jddst.2020.101879.
Texto completoWich, Peter R. y Jean M. J. Fréchet. "Degradable Dextran Particles for Gene Delivery Applications". Australian Journal of Chemistry 65, n.º 1 (2012): 15. http://dx.doi.org/10.1071/ch11370.
Texto completoKafshdooz, Taiebeh, Leila Kafshdooz, Abolfazl Akbarzadeh, Younes Hanifehpour y Sang Woo Joo. "Applications of nanoparticle systems in gene delivery and gene therapy". Artificial Cells, Nanomedicine, and Biotechnology 44, n.º 2 (3 de noviembre de 2014): 581–87. http://dx.doi.org/10.3109/21691401.2014.971805.
Texto completoContin, Mario, Cybele Garcia, Cecilia Dobrecky, Silvia Lucangioli y Norma D’Accorso. "Advances in drug delivery, gene delivery and therapeutic agents based on dendritic materials". Future Medicinal Chemistry 11, n.º 14 (julio de 2019): 1791–810. http://dx.doi.org/10.4155/fmc-2018-0452.
Texto completoTesis sobre el tema "GENE DELIVERY APPLICATIONS"
Twaites, Beverley Ruth. "Polymer-biopolymer interactions : applications in gene delivery". Thesis, University of Portsmouth, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.402281.
Texto completoShaw, Paul Andrew. "Improving gene delivery for gene therapy and DNA vaccination applications". Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614094.
Texto completoCifuentes, Rius Anna. "Tailoring Carbon Nanotubes Properties for Gene Delivery Applications". Doctoral thesis, Universitat Ramon Llull, 2013. http://hdl.handle.net/10803/127706.
Texto completoLa terapia génica se está convirtiendo en una técnica innovadora para curar enfermedades mediante la inserción de genes dentro de las células y órganos de un individuo. El reto recae en la liberación eficiente y segura de un acido nucleico terapéutico a los órganos objectivo. De todos los vectores sintéticos desarrollados recientemente, los nanotubos de carbono son una elección interesante que ya ha demostrado prometer considerablemente como sistema de liberación gracias a su proporción anchura-altura y su capacidad de traspasar la membrana celular. El problema que surge es su limitada solubilización i la agregación espontanea in vivo. Con el objetivo de desarrollar nuevos diseños basados en nanotubos de carbono para la formación de complejos capaces te transfectar ADN a las células, con un buen registro de biocompatibilidad y viabilidad celular, se han desarrollado diferentes estrategias. En primer lugar, se ha optimizado la funcionalización covalente de los nanotubos por medio de técnicas de plasma. Este tipo de modificación permite conseguir tanto superficies altamente reactivas capaces de unir ADN a traves de una molécula enlazante, como cargadas positivamente que permiten el envoltorio del acido nucleico por interacción electrostática. En segundo lugar, se han evaluado la dispersión de nanotubos de medidas diferentes por mediado de un agente estabilizante que incluye un surfactante un polímero amfifílico y proteínas. Esta naturaleza química de la superficie del nanotubo, junto con otras propiedades físicas como su longitud o diámetro, tiene un efecto directo en la dispersibilidad, citotoxicidad y biodistribución de estos sitemas. El uso de proteínas para funcionalizar nanopartículas es alentador ya que forma la corona de proteínas en su superficie. Dichos compuestos muestran una elevada capacidad de cargar ADN y permiten la regulación de su liberación mediante la manipulación de la composición de la corona.
Gene therapy has become an increasing innovative technique to treat disease by the insertion of genes into individual’s cells and tissues. The challenge is to efficiently and safely deliver the therapeutic nucleic acid into the target cells and organs. Among the synthetic vectors recently developed, carbon nanotubes are an interesting choice as they have already demonstrated considerable promise as delivery systems due to their high aspect ratio and their capacity to translocate the cell membrane. The problem that arises is their limited solubilization and spontaneous aggregation in vivo. Aiming to engineer new carbon nanotube-based designs for the formation of complexes able to transfect DNA/RNA to cells with a good track of biocompatibility and cell viability, different strategies have been developed. Firstly, the covalent functionalization of carbon nanotubes by plasma techniques has been optimized. This type of modification allows to either achieving highly reactive surfaces able to covalently bind DNA towards a chemical linker or a positively charged nanotube surface enabling the wrapping of the nucleic acid by electrostatic interaction. Secondly, the dispersion of the differently-sized carbon nanotubes by means of a stabilizing agent including a surfactant, an amphiphilic polymer and proteins has been assessed. The chemical nature of the modifying moieties on the carbon nanotube, alongside to other physical properties such as length or diameter, has a direct effect on the dispersibility, cytotoxicity and biodistribution of these systems. The use of proteins in the nanoparticle functionalization is encouraging due to the formation of the protein corona on its surface. Such complex exhibits high DNA load capacities and allows a tunable payload release by manipulating the corona composition
Uthe, Peter Benjamin Ashby Valerie. "The development of polycationic materials for gene delivery applications". Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2010. http://dc.lib.unc.edu/u?/etd,2917.
Texto completoTitle from electronic title page (viewed Jun. 23, 2010). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Chemistry." Discipline: Chemistry; Department/School: Chemistry.
TURCHIANO, GIANDOMENICO. "Defining an innovative and safe non-viral gene delivery system: perspective analysis for gene therapy applications". Doctoral thesis, Università degli Studi di Milano-Bicocca, 2013. http://hdl.handle.net/10281/43579.
Texto completoLaManna, Caroline Marie. "Synthesis, characterization, and evaluation of photo-active amphiphiles for gene delivery applications". Thesis, Boston University, 2013. https://hdl.handle.net/2144/12803.
Texto completoGene therapy has the potential to alter the landscape of medical therapeutic techniques by offering a means of introducing or knocking out genes to treat a number of diseases. Both viral and nonviral vectors are currently being utilized in gene therapy clinical trials. To overcome the obstacles in the cellular uptake and transfection pathways which impede nonviral gene delivery, novel lipids, polymers, and dendrimers are being engineered. Cationic lipid vectors have been widely characterized as gene delivery tools as they electrostatically interact with the anionic nucleic acid backbone to form a supramolecular structure (lipoplex). This complex allows the nucleic acid to be protected from enzymatic degradation during transport and interacts with the cell membrane to facilitate internalization by endocytosis. A limitation of current systems is a lack of mechanism for release of the nucleic acid, which is an integral step toward transcription and translation. The use of a charge-reversal or charge-switching amphiphile has been previously described by which the amphiphile initially has a net positive charge and is rendered negatively charged upon enzymatic removal of a terminal ester group. In order to further improve the transfection efficacy of cationic lipids and to impart an externally controlled release mechanism, we have developed a library of novel photo-active chargereversal lipids which can be triggered by ultraviolet (UV) light. In this work, we describe the synthesis and characterization of photo-active lipids for binding and releasing deoxyribonucleic acid (DNA) and evaluate the cellular uptake kinetics and transfection efficiency in vitro. The binding, release, and cellular uptake behaviors of lipoplexes were found to be dependent on lipid composition and resulting supramolecular structures. The transfection efficiency of the photo-active lipoplexes was further affected by variables associated with cellular incubation and UV exposure. Continued development of controlled release gene delivery vectors, including photoactive lipids, will enhance the understanding and utility of gene therapy by providing spatiotemporal control of the process.
Narayanasamy, Kaarjel Kauslya. "Preparation and evaluation of polymer coated magnetic nanoparticles for applications in gene delivery". Thesis, Keele University, 2018. http://eprints.keele.ac.uk/5002/.
Texto completoNelson, Ashley M. "Design of Functional Polyesters for Electronic and Biological Applications". Diss., Virginia Tech, 2015. http://hdl.handle.net/10919/74914.
Texto completoPh. D.
Allen, Michael H. Jr. "Imidazole-Containing Polymerized Ionic Liquids for Emerging Applications: From Gene Delivery to Thermoplastic Elastomers". Diss., Virginia Tech, 2013. http://hdl.handle.net/10919/49593.
Texto completoPh. D.
Perouzel, Eric. "Synthesis formulation and applications of new stabilisation agents for liposome based gene delivery system". Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271482.
Texto completoLibros sobre el tema "GENE DELIVERY APPLICATIONS"
M, Amiji Mansoor, ed. Polymeric gene delivery: Principles and applications. Boca Raton, Fla: CRC Press, 2005.
Buscar texto completoTwaites, Beverley Ruth. Polymer-biopolymer interactions: Applications in gene delivery. Portsmouth: University of Portsmouth, School of Pharmacy and Biomedical Sciences, 2004.
Buscar texto completoD, Lasic D. y Papahadjopoulos Demetrios, eds. Medical applications of liposomes. Amsterdam: Elsevier, 1998.
Buscar texto completoBremner, K. Helen. Application of nuclear localization sequences to non-viral gene delivery systems. Birmingham: University of Birmingham, 2002.
Buscar texto completoCarlisle, Robert. The application of adenovirus transduction mechanisms to enhance the activity of synthetic gene delivery systems. Birmingham: University of Birmingham, 2002.
Buscar texto completoZimmer, Vanessa. Gene Delivery: Methods and Applications. Nova Science Publishers, Incorporated, 2019.
Buscar texto completoGene Delivery: Methods and Applications. Nova Science Publishers, Incorporated, 2019.
Buscar texto completoAmiji, Mansoor M. Polymeric Gene Delivery: Principles and Applications. CRC, 2004.
Buscar texto completoAmiji, Mansoor M. Polymeric Gene Delivery: Principles and Applications. Taylor & Francis Group, 2004.
Buscar texto completoAmiji, Mansoor M. Polymeric Gene Delivery: Principles and Applications. Taylor & Francis Group, 2004.
Buscar texto completoCapítulos de libros sobre el tema "GENE DELIVERY APPLICATIONS"
Amponsah, Seth Kwabena, Ismaila Adams y Kwasi Agyei Bugyei. "Clinical Applications of siRNA". En Gene Delivery Systems, 65–76. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003186069-4.
Texto completoTrimal, Kavita y Kalpana Joshi. "COVID-19 Vaccine Development and Applications". En Gene Delivery Systems, 197–221. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003186069-12.
Texto completoBarua, Sonia y Yashwant Pathak. "siRNA Delivery for Therapeutic Applications Using Nanoparticles". En Gene Delivery Systems, 103–13. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003186083-8.
Texto completoFaldu, Khushboo, Sakshi Gurbani y Jigna Shah. "Clinical Applications of Gene Therapy for Immuno-Deficiencies". En Gene Delivery Systems, 195–206. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003186083-14.
Texto completoPandey, Prachi, Jayvadan Patel y Samarth Kumar. "CRISPER Gene Therapy Recent Trends and Clinical Applications". En Gene Delivery Systems, 179–94. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003186083-13.
Texto completoPatel, Kshama, Preetam Dasika y Yashwant V. Pathak. "The Current State of Non-Viral Vector–Based mRNA Medicine Using Various Nanotechnology Applications". En Gene Delivery Systems, 89–103. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003186069-6.
Texto completoSanthakumaran, Latha M., Alex Chen, C. K. S. Pillai, Thresia Thomas, Huixin He y T. J. Thomas. "Nanotechnology in Nonviral Gene Delivery". En Nanofabrication Towards Biomedical Applications, 251–87. Weinheim, FRG: Wiley-VCH Verlag GmbH & Co. KGaA, 2005. http://dx.doi.org/10.1002/3527603476.ch10.
Texto completoHalley, Patrick D., Christopher R. Lucas, Nikša Roki, Nicholas J. Vantangoli, Kurtis P. Chenoweth y Carlos E. Castro. "DNA Origami Nanodevices for Therapeutic Delivery Applications". En Biotechnologies for Gene Therapy, 161–94. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-93333-3_8.
Texto completoŠebestík, Jaroslav, Milan Reiniš y Jan Ježek. "Dendrimers in Gene Delivery". En Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures, 141–47. Vienna: Springer Vienna, 2012. http://dx.doi.org/10.1007/978-3-7091-1206-9_14.
Texto completoDev Jayant, Rahul, Abhijeet Joshi, Ajeet Kaushik, Sneham Tiwari, Rashmi Chaudhari, Rohit Srivastava y Madhavan Nair. "Chapter 8. Nanogels for Gene Delivery". En Nanogels for Biomedical Applications, 128–42. Cambridge: Royal Society of Chemistry, 2017. http://dx.doi.org/10.1039/9781788010481-00128.
Texto completoActas de conferencias sobre el tema "GENE DELIVERY APPLICATIONS"
Dandia, Hiren, Snehal Valvi, Rahul Thorat, Arvind Ingle, Abhijit De, Shubhada Chiplunkar y Prakriti Tayalia. "Scaffold Based Gene Delivery for Immunotherapeutic Applications". En National Research Scholars' Meet 2021 - Abstracts. Thieme Medical and Scientific Publishers Pvt. Ltd., 2022. http://dx.doi.org/10.1055/s-0042-1755513.
Texto completoFlick, Eva, Wenzhong Li, Jonas Norpoth, Christian Jooss, Gustav Steinhoff y Hans H. Gatzen. "Characterization of a Magnetic Microactuator for Manipulating Nanoparticles in Gene Delivery Applications". En ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13025.
Texto completoOlton, Dana, Dong Hyun Lee, Charles Sfeir y Prashant N. Kumta. "Novel Nanostructured Calcium Phosphate Based Delivery Systems for Non-Viral Gene Delivery". En ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176286.
Texto completoWeibing Lu, Hilal Gul, Peng Xu, Woon T. Ang, James Xing, Jian Zhang y Jie Chen. "A novel gene delivery system using magnetic nanodarts". En 2009 IEEE/NIH Life Science Systems and Applications Workshop (LiSSA) Formerly known as LSSA and. IEEE, 2009. http://dx.doi.org/10.1109/lissa.2009.4906738.
Texto completoJones, Frank R., Elizabeth S. Gabitzsch y Joseph P. Balint. "The Ad5 [E1-, E2b-]-based vector: a new and versatile gene delivery platform". En SPIE Sensing Technology + Applications, editado por Šárka O. Southern. SPIE, 2015. http://dx.doi.org/10.1117/12.2183244.
Texto completoWong, Peter, Michael A. Choi, Hilal Gul-Uludag, Woon T. Ang, Peng Xu, James Xing y Jie Chen. "Ultrasound-mediated gene delivery into hard-to-transfect KG-1 cells". En 2011 IEEE/NIH 5th Life Science Systems and Applications Workshop (LiSSA). IEEE, 2011. http://dx.doi.org/10.1109/lissa.2011.5754179.
Texto completoSerša, Gregor. "CLINICAL APPLICATIONS OF ELECTROCHEMOTHERAPY". En Symposium with International Participation HEART AND … Akademija nauka i umjetnosti Bosne i Hercegovine, 2019. http://dx.doi.org/10.5644/pi2019.181.01.
Texto completoBrown, Paige K., Ammar T. Qureshi, Daniel J. Hayes y W. Todd Monroe. "Targeted Gene Silencing With Light and a Silver Nanoparticle Antisense Delivery System". En ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53647.
Texto completoVlaskou, Dialechti, Pallab Pradhan, Christian Bergemann, Alexander L. Klibanov, Karin Hensel, Georg Schmitz, Christian Plank et al. "Magnetic Microbubbles: Magnetically Targeted and Ultrasound-Triggered Vectors for Gene Delivery in Vitro". En 8TH INTERNATIONAL CONFERENCE ON THE SCIENTIFIC AND CLINICAL APPLICATIONS OF MAGNETIC CARRIERS. AIP, 2010. http://dx.doi.org/10.1063/1.3530059.
Texto completoDelyagina, Evgenya, Wenzhong Li, Anna Schade, Anna-L. Kuhlo, Nan Ma, Gustav Steinhoff, Urs Häfeli, Wolfgang Schütt y Maciej Zborowski. "Low Molecular Weight Polyethyleneimine Conjugated to Magnetic Nanoparticles as a Vector for Gene Delivery". En 8TH INTERNATIONAL CONFERENCE ON THE SCIENTIFIC AND CLINICAL APPLICATIONS OF MAGNETIC CARRIERS. AIP, 2010. http://dx.doi.org/10.1063/1.3530058.
Texto completoInformes sobre el tema "GENE DELIVERY APPLICATIONS"
Radu, Daniela Rodica. Mesoporous Silica Nanomaterials for Applications in Catalysis, Sensing, Drug Delivery and Gene Transfection. Office of Scientific and Technical Information (OSTI), enero de 2004. http://dx.doi.org/10.2172/837277.
Texto completoHackett, Kevin, Shlomo Rottem, David L. Williamson y Meir Klein. Spiroplasmas as Biological Control Agents of Insect Pests. United States Department of Agriculture, julio de 1995. http://dx.doi.org/10.32747/1995.7613017.bard.
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