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Literatura académica sobre el tema "Gastric biomechanics"

Autor: Grafiati

Publicado: 5 de abril de 2025

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Artículos de revistas sobre el tema "Gastric biomechanics"

Kuhar, Sharun, Jung-Hee Seo, Pankaj J. Pasricha y Rajat Mittal. "Su1655 STOMACHSIM: AN IN-SILICO SIMULATOR OF GASTRIC BIOMECHANICS WITH APPLICATION TO PYLOROPLASTY". Gastroenterology 164, n.º 6 (mayo de 2023): S—639. http://dx.doi.org/10.1016/s0016-5085(23)02492-7.

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Estremera-Arevalo, Fermin, John Dent, Taher Omari y Jennifer Myers. "RA06.02: DETECTION OF ALTERED BOLUS TRANSPORT THROUGH THE ESOPHAGUS AND ESOPHAGO-GASTRIC JUNCTION IN PATIENTS WITH HIATUS HERNIA AND DYSPHAGIA". Diseases of the Esophagus 31, Supplement_1 (1 de septiembre de 2018): 30. http://dx.doi.org/10.1093/dote/doy089.ra06.02.

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Abstract Background Dysphagia can occur in patients with a small hiatus hernia (HH). Whether this relates to a pressure-flow variation through the esophagus or esophago-gastric junction (EGJ) is unknown. Methods High-resolution impedance manometry (HRIM) performed off therapy in 210 reflux patients and 25 age-matched healthy volunteers, recorded 10 × 5mL saline and likewise viscous bolus swallows. Esophageal pressure flow analysis (PFA) with AIMplot v8.0 was undertaken for valid bolus swallows. HRIM EGJ-subtype and endoscopic + /- fluoroscopic imaging enabled HH diagnosis (2–5 cm, > 5 cm excluded). Dysphagia was scored for difficulty swallowing 9 food types (Dakkak and Bennett; 0 none to 45 severe). ANOVA assessed differences in biomechanics of controls and HH + /- patients and dysphagia (D + , > 10/45). Results To date, findings for 135 patients (74M 61F, BMI 28, 19–41) with 70 HH + positive were compared with the 65 HH- negative and 25 healthy controls (7M 18F, BMI 27, 19–37)—see Table. In HH + there was increased resistance (intrabolus pressure) to bolus flow through the esophagus, while pressure during bolus clearance was lower. Further, a higher impedance ratio suggests less effective esophageal emptying, in addition to reduced EGJ outflow time. HH impairs transport of viscous and liquid swallows, affecting patients with HH + and troublesome dysphagia the most. Conclusion A small hiatus hernia alters biomechanics of bolus transport and hinders esophageal and esophago-gastric junction outflow, more so in patients with both dysphagia and hiatus hernia. These findings may relate to altered longitudinal muscle function associated with a short, flaccid esophagus when a hiatus hernia is present. Disclosure All authors have declared no conflicts of interest.

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Toniolo, Ilaria, Chiara Giulia Fontanella, Mirto Foletto y Emanuele Luigi Carniel. "Coupled experimental and computational approach to stomach biomechanics: Towards a validated characterization of gastric tissues mechanical properties". Journal of the Mechanical Behavior of Biomedical Materials 125 (enero de 2022): 104914. http://dx.doi.org/10.1016/j.jmbbm.2021.104914.

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Toniolo, Ilaria, Carlo Nostran, Edoardo Ferrari, Edoardo Fongaro, Chiara Fontanella, Mirto Foletto y Emanuele Carniel. "Patient-specific models of human resected stomach after laparoscopic sleeve gastrectomy: experimental and computational results". Russian Journal of Biomechanics 25, n.º 3 (30 de septiembre de 2021): 205–16. http://dx.doi.org/10.15593/rjbiomech/2021.3.02.

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The conspicuous increase in obesity rate occurring in the last decades in industrialized countries, often accompanied by high morbidity and high mortality rate, have been made obesity a global health concern. Bariatric surgery is the most effective treatment for severe obesity. However, there are still many issues related to surgical procedures not yet been overcome. The importance of experimenting with a new rational approach based on bioengineering methods could strongly improve surgical approach by avoiding drawbacks and complications. The aim of this work is the construction of patient-specific computational models of the resected stomachs after laparoscopic sleeve gastrectomy able to interpret the structural mechanical behavior of human gastric tissues. A coupled experimental-computational approach was performed. Experimental insufflation tests were performed on nine resected stomachs from laparoscopic sleeve gastrectomy. Through a reverse engineering approach, nine specific-patient computational models were developed, aiming at simulating the experimental activities. A double-layered fiber reinforced anisotropic hyperelastic material formulation was chosen. The experimental evidences provided the pressure-volume behavior of the resected stomachs. The comparison between experimental and computational results permitted to identify the set of the constitutive parameters. The stress-strain distribution described the region and the layer mainly solicited. An engineering approach allows us to characterize the mechanical behavior of the human gastric tissues. Reliable computational models will be used in understanding the biomechanics of the human stomach and will provide a clinical tool to help medical staff in optimizing bariatric procedures.

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Niu, Dong, Yanli Zhang, Jinlan Chen, Dachao Li, Chunmeng He y Hongzhong Liu. "Mechanobiology Platform Realized Using Photomechanical Mxene Nanocomposites: Bilayer Photoactuator Design and In Vitro Mechanical Forces Stimulation". Materials 15, n.º 19 (3 de octubre de 2022): 6869. http://dx.doi.org/10.3390/ma15196869.

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Mechanotransduction is the process by which cells convert external forces and physical constraints into biochemical signals that control several aspects of cellular behavior. A number of approaches have been proposed to investigate the mechanisms of mechanotransduction; however, it remains a great challenge to develop a platform for dynamic multivariate mechanical stimulation of single cells and small colonies of cells. In this study, we combined polydimethylsiloxane (PDMS) and PDMS/Mxene nanoplatelets (MNPs) to construct a soft bilayer nanocomposite for extracellular mechanical stimulation. Fast backlash actuation of the bilayer as a result of near-infrared irradiation caused mechanical force stimulation of cells in a controllable manner. The excellent controllability of the light intensity and frequency allowed backlash bending acceleration and frequency to be manipulated. As gastric gland carcinoma cell line MKN-45 was the research subject, mechanical force loading conditions could trigger apoptosis of the cells in a stimulation duration time-dependent manner. Cell apoptotic rates were positively related to the duration time. In the case of 6 min mechanical force loading, apoptotic cell percentage rose to 34.46% from 5.5% of the control. This approach helps apply extracellular mechanical forces, even with predesigned loading cycles, and provides a solution to study cell mechanotransduction in complex force conditions. It is also a promising therapeutic technique for combining physical therapy and biomechanics.

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Aasarød, Kristin M., Masoud Ramezanzadehkoldeh, Maziar Shabestari, Mats P. Mosti, Astrid K. Stunes, Janne E. Reseland, Vidar Beisvag et al. "Skeletal effects of a gastrin receptor antagonist in H+/K+ATPase beta subunit KO mice". Journal of Endocrinology 230, n.º 2 (agosto de 2016): 251–62. http://dx.doi.org/10.1530/joe-16-0017.

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Epidemiological studies suggest an increased fracture risk in patients taking proton pump inhibitors (PPIs) for long term. The underlying mechanism, however, has been disputed. By binding to the gastric proton pump, PPIs inhibit gastric acid secretion. We have previously shown that proton pump (H+/K+ATPase beta subunit) KO mice exhibit reduced bone mineral density (BMD) and inferior bone strength compared with WT mice. Patients using PPIs as well as these KO mice exhibit gastric hypoacidity, and subsequently increased serum concentrations of the hormone gastrin. In this study, we wanted to examine whether inhibition of the gastrin/CCK2 receptor influences bone quality in these mice. KO and WT mice were given either the gastrin/CCK2 receptor antagonist netazepide dissolved in polyethylene glycol (PEG) or only PEG for 1year. We found significantly lower bone mineral content and BMD, as well as inferior bone microarchitecture in KO mice compared with WT. Biomechanical properties by three-point bending test also proved inferior in KO mice. KO mice receiving netazepide exhibited significantly higher cortical thickness, cortical area fraction, trabecular thickness and trabecular BMD by micro-CT compared with the control group. Three-point bending test also showed higher Young’s modulus of elasticity in the netazepide KO group compared with control mice. In conclusion, we observed that the gastrin receptor antagonist netazepide slightly improved bone quality in this mouse model, suggesting that hypergastrinemia may contribute to deteriorated bone quality during acid inhibition.

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Hudson, P., S. Federer, M. Dunne, C. Pring y N. Smith. "DOES WEIGHT LOSS THROUGH BARIATRIC SURGERY REDUCE BIOMECHANICAL RISK FACTORS OF OSTEOARTHRITIS?" Orthopaedic Proceedings 106-B, SUPP_18 (14 de noviembre de 2024): 64. http://dx.doi.org/10.1302/1358-992x.2024.18.064.

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IntroductionWeight is a modifiable risk factor for osteoarthritis (OA) progression. Despite the emphasis on weight loss, data quantifying the changes seen in joint biomechanics are limited. Bariatric surgery patients experience rapid weight loss. This provides a suitable population to study changes in joint forces and function as weight changes.Method10 female patients undergoing gastric bypass or sleeve gastrectomy completed 3D walking gait analysis at a self-selected pace, pre- and 6 months post-surgery. Lower limb and torso kinematic data for 10 walking trials were collected using a Vicon motion capture system and kinetics using a Kistler force plate. An inverse kinematic model in Visual 3D allowed for no translation of the hip joint centre. 6 degrees of freedom were allowed at other joints. Data were analysed using JASP with a paired samples t-test.ResultOn average participants lost 28.8±7.60kg. No significant changes were observed in standing knee and hip joint angles. Walking velocity increased from 1.10±0.11 ms-1 to 1.23±0.17 ms-1 (t(9)=-3.060, p = 0.014) with no change in step time but a mean increase in stride length of 0.12m (SE: 0.026m; t(9)=-4.476, p = 0.002). A significant decrease of 21.5±4.2% in peak vertical ground reaction forces was observed (t(9)=12.863, p <0.001). Stride width significantly decreased by 0.04m (SE: 0.010m; t(9)=4.316, p = 0.002) along with a decrease in lateral impulse of 21.2Ns (SE: 6.977Ns; t(7), p = 0.019), but no significant difference in knee joint angles were observed. Double limb support time also significantly reduced by 0.02s (SE: 0.006s; t(9) = 3.639, p=0.005)ConclusionThe reduction in stance width and lateral impulse suggests a more sagittal compass-gait walk is being achieved. This would reduce valgus moments on the knee reducing loading in the medial compartment. The reduction in peak ground reaction force would reduce knee contact forces and again potentially slow OA progression.

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Díaz-Barreda, María Dolores, Ignacio Sánchez-Marín, Ana Boned-Murillo, Itziar Pérez-Navarro, Juana Martínez, Elena Pardina-Claver, Diana Pérez, Francisco Javier Ascaso y Juan Ibáñez. "Modification of Corneal Biomechanics and Intraocular Pressure Following Non-Penetrating Deep Sclerectomy". Journal of Clinical Medicine 11, n.º 5 (24 de febrero de 2022): 1216. http://dx.doi.org/10.3390/jcm11051216.

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Changes in the cornea can influence outcomes in patients with primary open-angle glaucoma (POAG). We aimed to evaluate the relevance of changes in corneal biomechanics and intraocular pressure (IOP) in patients undergoing non-penetrating deep sclerectomy (NPDS) with the Esnoper V2000 implant® (AJL Ophthalmic S.A., Gasteiz, Spain). We included 42 eyes of 42 patients with POAG scheduled for NPDS with the Esnoper V2000 implant. Biomechanical properties were measured by Ocular Response Analyzer® G3 (ORA; Reichert Inc., Depew, NY, USA). Corneal hysteresis (CH), corneal resistance factor (CRF), corneal compensated IOP (IOPcc), and Goldmann-correlated IOP (IOPg) were measured the day before surgery and on day 1, 7, and 30 and 2 and 3 months after surgery. CH initially increased, fell below the presurgical value at 30 days after the surgery, and increased again at 2 and 3 months. CRF, IOPcc, and IOPg decreased on the first day after surgery, then followed a trend of increasing but stayed below pre-surgery levels. All values reached statistical significance. While observed changes in corneal biomechanics after NPDS and Esnoper V2000 implant were significant, more studies are needed if we are to understand their influence on corneal biomechanics and their clinical relevance in POAG.

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Toniolo, Ilaria, Chiara Giulia Fontanella, Mirto Foletto y Emanuele Luigi Carniel. "Biomechanical Investigation of the Stomach Following Different Bariatric Surgery Approaches". Bioengineering 7, n.º 4 (9 de diciembre de 2020): 159. http://dx.doi.org/10.3390/bioengineering7040159.

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Background: The stomach is a hollow organ of the gastrointestinal tract, on which bariatric surgery (BS) is performed for the treatment of obesity. Even though BS is the most effective treatment for severe obesity, drawbacks and complications are still present because the intervention design is largely based on the surgeon’s expertise and intraoperative decisions. Bioengineering methods can be exploited to develop computational tools for more rational presurgical design and planning of the intervention. Methods: A computational mechanical model of the stomach was developed, considering the actual complexity of the biological structure, as the nonhomogeneous and multilayered configuration of the gastric wall. Mechanical behavior was characterized by means of an anisotropic visco-hyperelastic constitutive formulation of fiber-reinforced conformation, nonlinear elastic response, and time-dependent behavior, which assume the typical features of gastric wall mechanics. Model applications allowed for an analysis of the influence of BS techniques on stomach mechanical functionality through different computational analyses. Results: Computational results showed that laparoscopic sleeve gastrectomy and endoscopic sleeve gastroplasty drastically alter stomach capacity and stiffness, while laparoscopic adjustable gastric banding modestly affects stomach stiffness and capacity. Moreover, the mean elongation strain values, which are correlated to the mechanical stimulation of gastric receptors, were elevated in laparoscopic adjustable gastric banding compared to other procedures. Conclusions: The investigation of stomach mechanical response through computational models provides information on different topics such as stomach capacity and stiffness and the mechanical stimulation of gastric receptors, which interact with the brain to control satiety. These data can provide reliable support to surgeons in the presurgical decision-making process.

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Kerna, Nicholas A., N. D. Victor Carsrud, Xuan Zhao, Hilary M. Holets, Sudeep Chawla, John V. Flores, Dabeluchi C. Ngwu, Kevin D. Pruitt, Maria Khan y Rashad Roberson. "The Pathophysiology of Scoliosis Across the Spectrum of Human Physiological Systems". European Journal of Medical and Health Research 2, n.º 2 (1 de marzo de 2024): 69–81. http://dx.doi.org/10.59324/ejmhr.2024.2(2).07.

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Scoliosis is a medical condition characterized by an abnormal lateral curvature of the spine. It can lead to various health issues, affecting mobility, respiratory function, and overall quality of life. There are several types of scoliosis, including idiopathic, congenital, neuromuscular, degenerative, and functional. The severity of scoliosis is measured by the degree of spinal curvature, typically expressed in degrees through a system known as the Cobb angle. Early detection and intervention are fundamental in managing scoliosis, as more severe forms may necessitate bracing or surgical intervention. Healthcare professionals must understand the different types of scoliosis and their unique characteristics to tailor appropriate treatment plans.Scoliosis can significantly impact various physiological systems, including the circulatory, digestive, endocrine, integumentary, lymphatic, muscular, nervous, and respiratory systems. In the circulatory system, scoliosis can cause hemodynamic changes, impaired venous return, cardiac strain, and pulmonary complications. In the digestive system, scoliosis can lead to gastric displacement, impaired intra-abdominal pressure, gastroesophageal reflux, and nutritional implications. The endocrine system can be affected by scoliosis, leading to neuroendocrine dysregulation, growth hormone abnormalities, cortisol dysregulation, and impact on thyroid function. Scoliosis can also affect the integumentary system, leading to pressure ulcers, altered skin sensation, and hygiene challenges. In the lymphatic system, scoliosis can cause lymphatic obstruction, impaired immune response, altered inflammatory responses, fibrosis, and secondary lymphedema. Scoliosis can affect the muscular system, leading to muscle imbalance, myofascial pain, respiratory muscle weakness, and mobility issues. The nervous system can also be impacted by scoliosis, leading to neural compression, central nervous system impact, neurological dysfunction, and coordination challenges. In the respiratory system, scoliosis can cause thoracic deformities, reduced lung compliance, ventilation-perfusion mismatch, respiratory muscle weakness, increased work of breathing (WOB), and an increased risk of respiratory infections.Recognizing and addressing the interplay between scoliosis and these physiological systems is integral for healthcare professionals to provide comprehensive care to individuals with scoliosis.Current research on scoliosis has made progress in diagnostic tools and techniques, including the use of imaging methods like MRI and X-ray, wearable sensors, and 3D reconstruction techniques for better evaluation of spinal motion and function, along with treatment strategies like Schroth exercises and braces, and management measures for respiratory and circulatory problems. However, there are limitations to current studies, such as the heterogeneity of scoliosis, compartmentalized approaches, limited longitudinal studies, reliance on retrospective data, and the need for standardized measures and diagnostic criteria. Future research prospects include advancements in genetic research, biomechanics, artificial intelligence and machine learning, longitudinal studies, non-invasive treatments, and multidisciplinary collaborations among researchers, clinicians, and technologists.

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Tesis sobre el tema "Gastric biomechanics"

Feng, Jiajun. "Elucidation of the mechanisms of milk gastric digestion by means of a biomimetic in vitro dynamic model that incorporates the biomechanics of the stomach". Electronic Thesis or Diss., Institut Agro, 2025. http://www.theses.fr/2025AGRORA01.

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Les protéines du lait ont la propriété de coaguler rapidement dans l'estomac au cours de la digestion gastrique. Ce phénomène clé dans le processus de digestion in vivo a des répercussions importantes sur la cinétique de vidange gastrique et d'absorption des acides aminés. Pour mieux comprendre les mécanismes sous-jacents et leurs conséquences sur la bioaccessibilité des nutriments, les modèles de digestion dynamique in vitro, tel que le NEar Real Digestive Tract (NERDT), offrent une alternative prometteuse. Cette thèse s'est d’abord focalisée sur la conduite du NERDT pour reproduire les caractéristiques de la digestion gastrique in vivo du lait écrémé. Ce modèle biomimétique a ensuite été utilisé pour étudier les effets de l’ajout de pepsine, des contractions gastriques et de la température de consommation du lait sur sa digestion gastrique. Les résultats ont montré que la coagulation intragastrique du lait est favorisée par l'ajout de pepsine, les contractions gastriques et une température de consommation élevée (60°C), ralentissant la vidange gastrique des protéines et de la matière grasse. L’action de la pepsine et des contractions gastriques sont apparues complémentaires et synergiques lors de la désintégration ultérieure des particules laitières. Cette étude contribue à mieux comprendre comment la biomécanique gastrique affecte la digestion du lait, et appelle des recherches approfondies sur ce sujet. Une meilleure compréhension du comportement digestif des produits laitiers est en effet essentielle pour développer des aliments fonctionnels pour la santé et le bien-être des consommateurs
During gastric digestion, milk proteins display the property to rapidly coagulate within the stomach. This phenomenon is known to play a key role in the digestion process of milk, impacting the kinetics of gastric emptying and amino acid absorption in vivo. To better understand the mechanisms contributing to this phenomenon and its consequences on the bioaccessibility of nutrients, dynamic in vitro digestion systems, such as the NEar Real Digestive Tract (NERDT) system, offer promising alternatives. The first part of this study focused on the setting of the parameters of the NERDT system to reproduce relevant features of skimmed milk in vivo gastric digestion. This biomimetic digestion system was then used to investigate the effects of pepsin addition rate, gastric contraction and milk consumption temperature on the gastric digestion behaviour of milk. Results notably showed that milk intragastric coagulation is promoted by pepsin, gastric contraction, as well as a hot consumption temperature (60°C), after which a much slower gastric emptying of milk protein and fat was observed. The actions of pepsin and gastric contractions appeared to be highly complementary, acting synergically during the subsequent disintegration of the dairy particles. The present findings contribute to a deeper understanding of how variations in the gastric biomechanics may affect milk gastric digestion and call for more research on that topic. A better understanding of the digestive behaviour of dairy products can serve as a basis for the development of functional foods with benefits for the health and well-being of consumers

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(5930126), Daniel J. Pederson. "Determining, Treating, and Preventing Mechanisms of Sudden Death in Epilepsy using Medical Implantable Devices". Thesis, 2019.

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People with epilepsy have an increased risk of mortality when compared to the general population. These increased mortality risks include deaths related to status epilepticus and sudden unexpected death in epilepsy (SUDEP). Physiological data describing cardiac, respiratory, and brain function prior to sudden death in epilepsy is crucial to the studying the underlying mechanisms behind these deaths. Because it is unknown when sudden deaths in epilepsy may occur, continuous monitoring is necessary to guarantee the capture of physiological data prior to death.

I have used custom designed implantable devices to continuously measure cardiac, respiratory, and neurological signals in freely behaving rats with chronically induced epilepsy. Due to the continuous respiration measurements, the resultant dataset is the first of its kind. This dataset indicates that respiratory abnormalities (reduced respiration and short apneas) occur during and after seizures. These abnormalities may indicate SUDEP onset because obstructive apneas due to laryngospasm have been indicated as possible causes of SUDEP in other studies.

Laryngospasms can be caused by gastric acid coming into contact with the larynx. During a laryngospasm, intrinsic laryngeal muscles contract, resulting in the closure of the airway. Recently published research has indicated that acid reflux may be responsible for triggering fatal laryngospasms in rats with induced seizures. I have found that the larynx can be opened during a laryngospasm by electrically stimulating the recurrent laryngeal nerves. I have also found that performing gastric vagotomies leads to a statistically significant reduction in mortality due to fatal apneas in rats with induced seizures.

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Libros sobre el tema "Gastric biomechanics"

Gil, Nam Hong, ed. Mathematical foundations and biomechanics of the digestive system. Cambridge: Cambridge University Press, 2010.

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Capítulos de libros sobre el tema "Gastric biomechanics"

Miftahof, Roustem N. "Pharmacology of Gastric Dysmotility". En Biomechanics of the Human Stomach, 163–72. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-59677-8_9.

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Miftahof, Roustem N. "Prokinetics in Treatment of Gastric Motility Disorders". En Biomechanics of the Human Stomach, 245–58. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-59677-8_14.

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Yin, Jieyin y Jiande Chen. "Therapeutic Potential of Gastric Electrical Stimulation for Obesity". En Lecture Notes in Computational Vision and Biomechanics, 113–28. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6561-0_7.

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Griffith, James, Sumanth Daram, Ben Boatright, Joy Hughes, Christopher J. Lahr, Archana Kedar y Thomas L. Abell. "Gastric Electrical Stimulation: Twentieth Century Development to Twenty-First Century Implementation and Personalization of Programming". En Lecture Notes in Computational Vision and Biomechanics, 129–39. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6561-0_8.

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HAUSKEN, TRYGVE y SVEIN ØDEGAARD. "GASTRIC EMPTYING AND DUODENO-GASTRIC REFLUX ASSESSED BY DUPLEX SONOGRAPHY". En Advanced Series in Biomechanics, 337–58. WORLD SCIENTIFIC, 2005. http://dx.doi.org/10.1142/9789812569219_0011.

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HVEEM, KRISTIAN y HANS GREGERSEN. "SIMULTANEOUS RECORDINGS OF GASTRIC MOTILITY BY ULTRASOUND, SCINTIGRAPHY AND MANOMETRY". En Advanced Series in Biomechanics, 189–209. WORLD SCIENTIFIC, 2005. http://dx.doi.org/10.1142/9789812569219_0006.

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Actas de conferencias sobre el tema "Gastric biomechanics"

Howes, Meghan K. y Warren N. Hardy. "Material Properties of the Post-Mortem Stomach in High-Rate Equibiaxial Elongation". En ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80842.

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Risk of serious abdominal injury in motor vehicle collisions (MVCs) is substantially reduced with the proper use of seatbelts [1]. However, a significant increase in occurrence of gastrointestinal tract injury exists with belt loading [2]. Crash-induced injuries of the stomach that occur in MVCs include gastric rupture and laceration [3]. To characterize the biomechanical response of the stomach associated with these failure modes, the multidirectional failure properties of cruciate tissue samples were investigated with high-rate biaxial stretch.

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Komolafe, Oluseeni A. y Todd C. Doehring. "Nonlinear Elastic Behavior of Achilles Tendon at the Fascicle Scale". En ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176880.

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Parallel collagen fibers such as ligaments and tendons are composed of fiber bundles, or fascicles, enclosed in a sheath of reticular membrane. In the Achilles tendon, these fascicles can be long, extending from the gastro-soleus unit to the calcaneal insertion site (Fig. 1). Although the overall functional behavior of the whole tendon is well established[1], there is little information detailing properties of individual fascicles or their interactions. Knowledge of the structural and biomechanical properties at the “mesostructural” scale (i.e. fascicle-scale) is critical to understanding tissue pathologies; in particular the processes involved in injury and healing, and the development of improved computational models and functional tissue engineered constructs.

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Xu, Jack, Leo K. Cheng, Recep Avci y Peng Du. "Reconstruction of the Gastro-esophageal Junction Based on Ultramill Imaging for Biomechanical Analysis". En 2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). IEEE, 2022. http://dx.doi.org/10.1109/embc48229.2022.9871765.

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