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1

Furrer, Frank J. Safety and Security of Cyber-Physical Systems. Wiesbaden: Springer Fachmedien Wiesbaden, 2022. http://dx.doi.org/10.1007/978-3-658-37182-1.

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2

Ferrari, Riccardo M. G. y André M. H. Teixeira, eds. Safety, Security and Privacy for Cyber-Physical Systems. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-65048-3.

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3

Sayed-Mouchaweh, Moamar, ed. Diagnosability, Security and Safety of Hybrid Dynamic and Cyber-Physical Systems. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-74962-4.

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4

Griffor, Edward. Handbook of System Safety and Security: Cyber Risk and Risk Management, Cyber Security, Threat Analysis, Functional Safety, Software Systems, and Cyber Physical Systems. Elsevier Science & Technology Books, 2016.

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5

Griffor, Edward. Handbook of System Safety and Security: Cyber Risk and Risk Management, Cyber Security, Threat Analysis, Functional Safety, Software Systems, and Cyber Physical Systems. Elsevier Science & Technology Books, 2016.

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6

Ferrari, Riccardo M. G. y André M. H. Teixeira. Safety, Security and Privacy for Cyber-Physical Systems. Springer International Publishing AG, 2022.

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7

Ferrari, Riccardo M. G. y André M. H. Teixeira. Safety, Security, and Privacy for Cyber-Physical Systems. Springer International Publishing AG, 2021.

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8

Ward, David y Paul Wooderson. Automotive Cybersecurity: An Introduction to ISO/SAE 21434. SAE International, 2021. http://dx.doi.org/10.4271/9781468600810.

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Industries, regulators, and consumers alike see cybersecurity as an ongoing challenge in our digital world. Protecting and defending computer assets against malicious attacks is a part of our everyday lives. From personal computing devices to online financial transactions to sensitive healthcare data, cyber crimes can affect anyone. As technology becomes more deeply embedded into cars in general, securing the global automotive infrastructure from cybercriminals who want to steal data and take control of automated systems for malicious purposes becomes a top priority for the industry. Systems and components that govern safety must be protected from harmful attacks, unauthorized access, damage, or anything else that might interfere with safety functions. Automotive Cybersecurity: An Introduction to ISO/SAE 21434 provides readers with an overview of the standard developed to help manufacturers keep up with changing technology and cyber-attack methods. ISO/SAE 21434 presents a comprehensive cybersecurity tool that addresses all the needs and challenges at a global level. Industry experts, David Ward and Paul Wooderson, break down the complex topic to just what you need to know to get started including a chapter dedicated to frequently asked questions. Topics include defining cybersecurity, understanding cybersecurity as it applies to automotive cyber-physical systems, establishing a cybersecurity process for your company, and explaining assurances and certification.
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9

Diagnosability, Security and Safety of Hybrid Dynamic and Cyber-Physical Systems. Springer, 2018.

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10

Sayed-Mouchaweh, Moamar. Diagnosability, Security and Safety of Hybrid Dynamic and Cyber-Physical Systems. Springer International Publishing AG, 2018.

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11

Furrer, Frank J. Safety and Security of Cyber-Physical Systems: Engineering Dependable Software Using Principle-Based Development. Springer Fachmedien Wiesbaden GmbH, 2022.

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12

Innominato, Pasquale F. y David Spiegel. Circadian rhythms, sleep, and anti-cancer treatments. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198778240.003.0016.

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The circadian timing system temporally regulates biological functions relevant for psycho-physical wellbeing, spanning all the systems related to health. Hence, disruption of circadian rhythms, along with sleep cycles, is associated with the development of several diseases, including cancer. Moreover, altered circadian and sleep functions negatively impact on cancer patients’ quality of life and survival, above and beyond known determinants of outcome. This alteration can occur as a consequence of cancer, but also of anti-cancer treatments. Indeed, circadian rhythms govern also the ability of detoxifying chemotherapy agents across the 24 hours. Hence, adapting chemotherapy delivery to the molecular oscillations in relevant drug pathways can decrease toxicity to healthy cells, while increasing the number of cancer cells killing. This chronomodulated chemotherapy approach, together with the maintenance of proper circadian function throughtout the whole disease challenge, would finally result in safer and more active anticancer treatments, and in patients experiencing better quality and quantity of life.
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13

Gao, Feng, Yang Xu, Pengfei Gu, Yongbin Sun y Yanyang Liu. Nuclear Power Plants : Innovative Technologies for Instrumentation and Control Systems: The Fifth International Symposium on Software Reliability, Industrial Safety, Cyber Security and Physical Protection of Nuclear Power Plant. Springer, 2022.

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14

Wang, Yanjun, Yang Xu, Pengfei Gu, Yongbin Sun y Yanyang Liu. Nuclear Power Plants : Innovative Technologies for Instrumentation and Control Systems: The Fourth International Symposium on Software Reliability, Industrial Safety, Cyber Security and Physical Protection of Nuclear Power Plant. Springer Singapore Pte. Limited, 2021.

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15

Liu, Zheming, Yang Xu, Pengfei Gu, Yongbin Sun y Yanyang Liu. Nuclear Power Plants : Innovative Technologies for Instrumentation and Control Systems: The Fifth International Symposium on Software Reliability, Industrial Safety, Cyber Security and Physical Protection of Nuclear Power Plant. Springer Singapore Pte. Limited, 2021.

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16

Gao, Feng, Yang Xu, Pengfei Gu, Yongbin Sun y Yanyang Liu. Nuclear Power Plants : Innovative Technologies for Instrumentation and Control Systems: The Sixth International Symposium on Software Reliability, Industrial Safety, Cyber Security and Physical Protection of Nuclear Power Plant. Springer, 2022.

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17

Porges, Stephen W. Vagal Pathways. Editado por Emma M. Seppälä, Emiliana Simon-Thomas, Stephanie L. Brown, Monica C. Worline, C. Daryl Cameron y James R. Doty. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780190464684.013.15.

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In this chapter, contemplative practices are conceptualized as methods that function as neural exercises enhancing vagal regulation of the autonomic nervous system. The model presented proposes that specific voluntary behaviors (e.g., breath, vocalizations, and posture), which characterize ancient rituals and form the core of contemplative practices, can trigger a physiological state mediated by vagal pathways that fosters health and optimizes subjective experiences. The model emphasizes that, in order for the positive benefits of contemplative practices to be experienced, the rituals associated with contemplative practices (e.g., chants, prayers, meditation, and dance) must be performed in a context defined by physical features that are calming and soothing and promote feelings of safety.
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18

Bannwarth, Bernard y Francis Berenbaum. Systemic analgesics (including paracetamol and opioids). Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0029.

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Apart from non-steroidal anti-inflammatory drugs (NSAIDs), there are only two categories of systemic analgesics, namely paracetamol (acetaminophen) and opioids, that are currently available worldwide for clinical use. Paracetamol is poorly effective in relieving pain and improving function in patients with symptomatic osteoarthritis (OA). Furthermore, its safety profile is less favourable than classically thought. In fact, there is evidence paracetamol acts as a weak inhibitor of the cyclooxygenase enzymes. Given that paracetamol poses a lower risk of severe adverse events than NSAIDs while being better tolerated than opioids, it is usually considered as the first-line systemic analgesic for OA. Commonly prescribed opioids are primarily agonists of the mu receptors, thereby producing similar desirable (analgesia) and untoward effects. Meta-analyses of short-term clinical trials showed that, on average, the modest clinical benefits of opioids did not outweigh the side effects in patients with knee or hip OA. Accordingly, most current guidelines support the use of opioids for selected OA patients only (e.g. patients who have not had an adequate response to other treatment modalities and are not candidates for total joint arthroplasty). In view of the limited efficacy and/or potential harms of available analgesics, particular attention was paid to novel painkillers, especially nerve growth factor (NGF) antagonists. Although these agents provided clinically meaningful improvements in pain and physical function in patients with hip or knee OA, they lead to severe side effects, including rapidly destructive arthropathies and neuropathies. Thus, if approved for marketing, NGF antagonists would be reserved for selected and well-defined patients with OA.
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19

Quinn, Tom y Eva Swahn. The intensive cardiac care unit team. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0011.

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Effective, safe health care is a multidisciplinary undertaking. From its inception, half a century ago, the concept of intensive coronary (now cardiac) care has drawn on the expertise of a range of professionals, particularly physicians working closely with nurses. As the evidence base for some aspects of the intensive cardiac care unit care has developed, the intensive cardiac care unit, in some instances, has striking similarities to the general intensive care unit, while paradoxically traditional intensive cardiac care unit functions have been devolved to other parts of the health care system such as the emergency department or pre-hospital care, and the concept of critical care ‘outreach’ has been further developed to take the expertise to patients on the general ward or even in the pre-hospital phase. With more intensive treatment policies for older people becoming the norm, the range of multi-comorbidities to be addressed by the clinical team requires input from a range of other specialties. Moreover, the increasing complexity of diagnostic and interventional techniques requires close collaboration with laboratory and imaging personnel. Thus, the intensive cardiac care unit team arguably extends beyond staff working solely within the physical structure of the intensive cardiac care unit to encompass a range of other professional and support staff, both within and outside the hospital setting.
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20

Quinn, Tom y Eva Swahn. The intensive cardiac care unit team. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0011_update_001.

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Effective, safe health care is a multidisciplinary undertaking. From its inception, half a century ago, the concept of intensive coronary (now cardiac) care has drawn on the expertise of a range of professionals, particularly physicians working closely with nurses. As the evidence base for some aspects of the intensive cardiac care unit care has developed, the intensive cardiac care unit, in some instances, has striking similarities to the general intensive care unit, while paradoxically traditional intensive cardiac care unit functions have been devolved to other parts of the health care system such as the emergency department or pre-hospital care, and the concept of critical care ‘outreach’ has been further developed to take the expertise to patients on the general ward or even in the pre-hospital phase. With more intensive treatment policies for older people becoming the norm, the range of multi-comorbidities to be addressed by the clinical team requires input from a range of other specialties. Moreover, the increasing complexity of diagnostic and interventional techniques requires close collaboration with laboratory and imaging personnel. Thus, the intensive cardiac care unit team arguably extends beyond staff working solely within the physical structure of the intensive cardiac care unit to encompass a range of other professional and support staff, both within and outside the hospital setting.
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21

DeNardis, Laura. The Internet in Everything. Yale University Press, 2020. http://dx.doi.org/10.12987/yale/9780300233070.001.0001.

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The Internet has leapt from human-facing display screens into the material objects all around us. In this so-called Internet of Things—connecting everything from cars to cardiac monitors to home appliances—there is no longer a meaningful distinction between physical and virtual worlds. Everything is connected. The social and economic benefits are tremendous, but there is a downside: an outage in cyberspace can result not only in a loss of communication but also potentially a loss of life. Control of this infrastructure has become a proxy for political power, since countries can easily reach across borders to disrupt real-world systems. This book argues that this diffusion of the Internet into the physical world radically escalates governance concerns around privacy, discrimination, human safety, democracy, and national security, and it offers new cyber-policy solutions. The book makes visible the sinews of power already embedded in our technology and explores how hidden technical governance arrangements will become the constitution of our future.
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