Literatura académica sobre el tema "Facile Michael Addition Reaction"
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Artículos de revistas sobre el tema "Facile Michael Addition Reaction"
Reddy, S. Madhava y H. M. Walborsky. "A facile intramolecular Michael addition reaction". Journal of Organic Chemistry 51, n.º 13 (junio de 1986): 2605–7. http://dx.doi.org/10.1021/jo00363a042.
Texto completoStepanova, Ekaterina, Andrey Maslivets, Svetlana Kasatkina y Maksim Dmitriev. "Diversity-Oriented Synthesis via Catalyst-Free Addition of Ketones to [e]-Fused 1H-Pyrrole-2,3-diones". Synthesis 50, n.º 24 (20 de agosto de 2018): 4897–904. http://dx.doi.org/10.1055/s-0037-1610647.
Texto completoWang, Yi-Fan, Cheng-Yu He, Longlei Hou, Ping Tian, Guo-Qiang Lin y Xiaofeng Tong. "Facile Access to 1,5-Benzodiazepines via Amine-Promoted (4+3) Annulations of δ-Acetoxy Allenoates with o-Diaminobenzenes under Mild Conditions". Synlett 29, n.º 09 (23 de marzo de 2018): 1176–80. http://dx.doi.org/10.1055/s-0037-1609347.
Texto completoYang, Jingya, Tianyuan Li, Hongyan Zhou, Nana Li, Dongtai Xie y Zheng Li. "Potassium Hydroxide Catalysed Intermolecular Aza-Michael Addition of 3-Cyanoindole to Aromatic Enones". Synlett 28, n.º 10 (28 de febrero de 2017): 1227–31. http://dx.doi.org/10.1055/s-0036-1588152.
Texto completoTerent'ev, Alexander O., Vera A. Vil', Ivan A. Yaremenko, Oleg V. Bityukov, Dmitri O. Levitsky, Vladimir V. Chernyshev, Gennady I. Nikishin y Fabrice Fleury. "Preparation of a microsized cerium chloride-based catalyst and its application in the Michael addition of β-diketones to vinyl ketones". New J. Chem. 38, n.º 4 (2014): 1493–502. http://dx.doi.org/10.1039/c3nj01454a.
Texto completoBoruah, Romesh C., Anil Saikia, Apurba Chetia y Utpal Bora. "A Facile Synthesis of 1,6-Diketonesvia a Three-Component Michael Addition Reaction". Synlett, n.º 10 (2003): 1506–8. http://dx.doi.org/10.1055/s-2003-40821.
Texto completoRulev, Alexander Yu, Alexey R. Romanov, Alexander V. Popov, Evgeniy V. Kondrashov y Sergey V. Zinchenko. "Reaction of Bromoenones with Amidines: A Simple Catalyst-Free Approach to Trifluoromethylated Pyrimidines". Synthesis 52, n.º 10 (9 de marzo de 2020): 1512–22. http://dx.doi.org/10.1055/s-0040-1707969.
Texto completoLin, Ning, Qiu-Xiang Wei, Li-Hua Jiang, Yan-Qiu Deng, Zhen-Wei Zhang y Qing Chen. "Asymmetric Michael Addition of Malononitrile with Chalcones via Rosin-Derived Bifunctional Squaramide". Catalysts 10, n.º 1 (20 de diciembre de 2019): 14. http://dx.doi.org/10.3390/catal10010014.
Texto completoGuy Taylor, Jason, Wellington Martins Ventura y Luiz Guilherme Souza de Assis. "Facile Synthesis of Indolines by a Tandem Nitro-reduction Aza Michael Addition Reaction". HETEROCYCLES 87, n.º 10 (2013): 2023. http://dx.doi.org/10.3987/com-13-12789.
Texto completoFustero, Santos, Javier Moscardó, María Sánchez-Roselló, Elsa Rodríguez y Pablo Barrio. "Tandem Nucleophilic Addition−Intramolecular Aza-Michael Reaction: Facile Synthesis of Chiral Fluorinated Isoindolines". Organic Letters 12, n.º 23 (3 de diciembre de 2010): 5494–97. http://dx.doi.org/10.1021/ol102341n.
Texto completoTesis sobre el tema "Facile Michael Addition Reaction"
Budhavaram, Naresh Kumar. "Facile protein and amino acid substitution reactions and their characterization using thermal, mechanical and optical techniques". Diss., Virginia Tech, 2010. http://hdl.handle.net/10919/40340.
Texto completoPh. D.
Jha, Sushil C. "Catalytic, enantioselective michael addition reaction". Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2002. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2496.
Texto completoLombardi, Federico. "Computational study on the asymmetric aminocatalysed Michael addition reaction of cyclohexanone to trans–β–nitrostyrene". Master's thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amslaurea.unibo.it/23186/.
Texto completoZhu, Sunsheng. "Novel Approach to Polyhedral Oligmeric Silsesquioxane-Based Giant Surfactants Basd on Thiol-Michael Addition "Click" Reaction". University of Akron / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=akron1399555570.
Texto completoLi, Mao. "Iron(III) catalyzed asymmetric Diels-Alder reaction - Iron(II) catalyzed thia-Michael addition and aldehyde allylation reactions". Doctoral thesis, Université Laval, 2019. http://hdl.handle.net/20.500.11794/34969.
Texto completoIron catalysts are employed in three different organic transformations owing to their advantages: environmental friendliness, being less expensive and abundant on the Earth. The first project deals with asymmetric Diels-Alder reactions of α, β-unsaturated oxazolidin-2-one derivatives catalyzed by Fe¹¹¹ and a chiral bipyridine ligand. In order to obtain the optimized reaction conditions, we screened different solvents, catalyst loading, various reaction times and a variety of iron salts such as Fe(ClO₄)₂·6H₂O, Fe(ClO₄)₂·6H₂O, Fe(OTf)₃, Fe(OTf)₂, FeCl₂, FeCl₃, FeBr₃ and FeI₃. As a result, the reaction between cyclopentadiene and 3-alkenoyl-1,3-oxazolidin-2-one was carried out at –30 °C in CH₃CN in 1.5 h, with Fe(ClO₄)₃·6H₂O (2 mol%) complexed with the chiral bipyridine ligand (2.4 mol%) as catalyst, providing an excellent yield (99%) and an excellent enantiomeric excess (98%). Decreased enantioselectivities were observed for less-reactive dienes. Overall, less than 10 mol% of catalyst loading was employed. The great advantages of this project are the mild reaction temperature, very low catalyst loading, excellent yields and enantioselectivities and the applicability to a wide scope of substrates. Meanwhile, iron catalysts were used in thia-Michael additions by two different approaches. The first one is about thia-Michael additions catalyzed by Fe(OTf)₂ in EtOH at room temperature. This green method allows the thia-Michael additions to be catalyzed by a green iron salt (5 mol% of Fe(OTf)₂), a green and commonly used solvent EtOH at room temperature under ambient atmosphere. The generality of this reaction was demonstrated by applying it to different Michael acceptors, and to aromatic and aliphatic thiols. The second method is about thia-Michael additions catalyzed by Fe(OTf)₂ in 2-Me-THF, which is in agreement with the green chemistry principles by using a green Fe(OTf)₂ and a green solvent 2-Me-THF at room temperature or 50 °C under air atmosphere. The last project is about asymmetric allylation reactions catalyzed by Fe(OTf)₂ using a chiral ligand. With the study of a variety of chiral ligands, we selected 5 mol% of Fe(OTf)₂ and 6 mol% of Pybox ligand which catalyzed the reaction in good yield (70%) and 32% of ee. The utilization of 20 mol% of TMSCl is essential for the effectiveness of the reaction
LOPS, CARMINE. "Development of organocatalytic and stereoselective reactions". Doctoral thesis, Università degli Studi di Trieste, 2018. http://hdl.handle.net/11368/2918472.
Texto completoIbrahim, Houssein. "Synthèse de nouveaux composés chiraux à partir d'isosorbide et d'isomannide : applications en catalyse asymétrique". Thesis, Paris 11, 2011. http://www.theses.fr/2011PA112159.
Texto completoThe Thesis deals with the synthesis of new chiral compounds derived from isosorbide and isomannide and their applications to asymmetric catalysis. The first part of this work consisted in perfecting the chemical and enantioselective hydrogenation conditions of olefins using chiral monophosphines as ligands (up to 96% ee). These phosphines were also used as organocatalysts for [3+2] cyclisation reactions showing good catalytic activity and moderate enantioselectivity. The second part turned to the synthesis of a series of chiral nitrogen compounds which were evaluated in the asymmetric transfer hydrogenation of aromatic ketones giving good enantioselectivity (up to 73% ee). The complexes formed with amine ligands were also applied to the addition reaction of phenylacetylene to imines. Good catalytic activity but low enantioselectivity were observed. These nitrogen compounds were also used as organocatalysts in the Michael addition reaction of aromatic ketones to the nitrostyrene. Again, low enantiomeric excess was obtained. The last part of this work consisted in preparing new chiral thiourea compounds which were applied as organocatalysts to the Friedel-Crafts alkylation reaction of different indoles with nitroolefines, and to the conjugate addition reaction of hydroxylamines to pyrazoles derivatives for the synthesis of β-amino acids. In two cases, these catalysts have proved active but not enantioselective
Guedeney, Nicolas. "Vers la vectorisation des bisphophonates par les peptides de pénétration cellulaire". Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCD024.
Texto completoNowadays, one of the main strategies for pharmacokinetic modifications of bioactive compounds is their vectorization and the synthesis of prodrug derivatives. This work is focused on the vectorization of phosphorus antitumor agents with cell-penetrating peptides. We have then conjugated aminoalkyl-bisphosphonates with peptidic sequence to modify their retention time and increase their cellular internalization. Several linkers bearing an insaturated carbonyl moiety have been evaluated in conjugation by aza- and thia-Michael addition reaction to obtain a conjugated peptide-alendronate compounds. A prodrug approach has been conducted with the synthesis of bisphosphinate derivatives and an analog of alendronate has been obtained
Léger, Frédéric. "Additions d'énamines β-lithiées sur des esters α, β-éthyléniques. Nouvelles propriétés des énamines β-halogénées". Rouen, 1996. http://www.theses.fr/1996ROUES051.
Texto completoGoudedranche, Sébastien. "Réactions domino organocatalysées énantiosélectives à partir de cétoamides". Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM4354.
Texto completoThis work focused on the development of novel enantioselective transformations combining Multiples Bond-Forming Transformations and organocatalysis which are modern tools of organic synthesis in order to synthetize molecules of structural and biological interests. In this context, we developed two new Michael addition initiated domino reactions. The first one, a domino Michael addition-acylation, allows the synthesis of optically active spiroglutarimides starting from β-ketoamides and α,β-unsaturated acyles cyanides as new biselectrophiles.The second one, a domino Michael addition-hemiaminalizationhemiacetalization, allows the synthesis of seven-membered aza-cycles using α-ketoamides as new bis-nucleophiles
Capítulos de libros sobre el tema "Facile Michael Addition Reaction"
Oare, David A. y Clayton H. Heathcock. "Stereochemistry of the Base-Promoted Michael Addition Reaction". En Topics in Stereochemistry, 227–407. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470147283.ch5.
Texto completoGuan, Xiaoyuan, Guangxue Chen, Rui Guo, Zhaohui Yu y Minghui He. "Thiol-ene Michael Addition Reaction Under Phototriggered Base Proliferation". En Lecture Notes in Electrical Engineering, 909–18. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-7629-9_113.
Texto completoTomioka, Kiyoshi. "Five Step Asymmetric Total Synthesis of β-Lycorane Employing Chiral Diether Ligand-Controlled Conjugate Addition-Michael Reaction Cascade". En New Horizons of Process Chemistry, 191–200. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-3421-3_14.
Texto completoTaber, Douglass F. "The Magnus Synthesis of ( ± )-Codeine". En Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0088.
Texto completoLambert, Tristan H. "C–O Ring Formation". En Organic Synthesis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190646165.003.0044.
Texto completoTaber, Douglass F. "The Deslongchamps Synthesis of (+)-Cassaine". En Organic Synthesis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190646165.003.0091.
Texto completoTaber, Douglass F. "Enantioselective Synthesis of Alcohols and Amines: The Doi Synthesis of Apratoxin C". En Organic Synthesis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190646165.003.0034.
Texto completoMarsden, S. P. "Tandem Michael Addition/Intramolecular Aldol Reaction (Robinson Annulation)". En Ketones, 1. Georg Thieme Verlag KG, 2005. http://dx.doi.org/10.1055/sos-sd-026-01026.
Texto completoTidwell, T. T. "Michael Addition and Elimination Reaction of Alkanoate Esters". En Three Carbon-Heteroatom Bonds: Thio-, Seleno-, and Tellurocarboxylic Acids and Derivatives; Imidic Acids and Derivatives; Ortho Acid Derivatives, 1. Georg Thieme Verlag KG, 2006. http://dx.doi.org/10.1055/sos-sd-023-00542.
Texto completoFrey, Perry A. y Adrian D. Hegeman. "Addition and Elimination". En Enzymatic Reaction Mechanisms. Oxford University Press, 2007. http://dx.doi.org/10.1093/oso/9780195122589.003.0013.
Texto completoActas de conferencias sobre el tema "Facile Michael Addition Reaction"
Scott, T. W. "Picosecond Addition and β-Scission Reactions of Thiyl Radicals with Unsaturated Hydrocarbons". En International Conference on Ultrafast Phenomena. Washington, D.C.: Optica Publishing Group, 1986. http://dx.doi.org/10.1364/up.1986.mf7.
Texto completoForghani, A., L. Garber, C. Chen, R. Devireddy, J. Pojman y D. Hayes. "In Situ Polymerization of PEGDA Foam for Bone Defects". En ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-51235.
Texto completoZhong, Hanyi, Ying Guan, Zhengsong Qiu, Jie Feng, Wenlei Liu, Yuan Wan y Yubin Zhang. "Improvement of Rheological and Filtration Properties of Water-Based Drilling Fluids Using Bentonite-Hydrothermal Carbon Nanocomposites Under the Ultra-High Temperature and High Pressure Conditions". En SPE/IATMI Asia Pacific Oil & Gas Conference and Exhibition. SPE, 2021. http://dx.doi.org/10.2118/205539-ms.
Texto completoKote, Prashant, Magdalen Asare, Sahilkumar Chaudhary, Tim Dawsey y Ram Gupta. "Flame Retardant Polyurethane Foams Using Vegetable Oil-based polyol". En 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/iefv6816.
Texto completoShqau, Krenar y Amy Heintz. "Mixed Ionic Electronic Conductors for Improved Charge Transport in Electrotherapeutic Devices". En 2017 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/dmd2017-3454.
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