Tesis sobre el tema "Exhaled nitric oxide"
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Kharitonov, Sergei Alexandrovich. "Exhaled nitric oxide in airway diseases". Thesis, Imperial College London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266411.
Texto completoHemmingsson, Tryggve. "Exhaled nitric oxide in extreme environments". Stockholm : Karolinska institutet, 2009. http://diss.kib.ki.se/2009/978-91-7409-609-5/.
Texto completoLiu, Jia Clinical School Prince of Wales Hospital Faculty of Medicine UNSW. "Nitric oxide in airway inflammation". Publisher:University of New South Wales. Clinical School - Prince of Wales Hospital, 2009. http://handle.unsw.edu.au/1959.4/43678.
Texto completoRatnawati, Ratnawati Prince of Wale Hospital Clinical School UNSW. "Exhaled nitric oxide in asthmatic airway inflammation". Awarded by:University of New South Wales. Prince of Wale Hospital Clinical School, 2006. http://handle.unsw.edu.au/1959.4/25729.
Texto completoPedroletti, Christophe. "Exhaled nitric oxide in schoolchildren with asthma /". Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-164-4/.
Texto completoMarteus, Helena. "Oropharyngeal origin of markers in exhaled breath /". Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-274-8/.
Texto completoMitchell, Colin. "The Association Between Exhaled Nitric Oxide in Exhaled Breath Condensate and Chronic Obstructive Pulmonary Disease". ScholarWorks, 2015. https://scholarworks.waldenu.edu/dissertations/397.
Texto completoHazari, Mehdi Saeed. "Elevated exhaled nitric oxide (ENO) in non-asthmatic atopic adults". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ58853.pdf.
Texto completoTörnberg, Daniel C. F. "Exhaled nitric oxide : influence of mechanical ventilation and vasoactive agents /". Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-070-2/.
Texto completoSmith, Andrew D. y n/a. "Exhaled nitric oxide measurements in the diagnosis and management of asthma". University of Otago. Dunedin School of Medicine, 2007. http://adt.otago.ac.nz./public/adt-NZDU20070924.133734.
Texto completoSheel, Andrew William. "Relationship between exhaled and inhaled nitric oxide and exercise-induced hypoxemia". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0015/NQ48711.pdf.
Texto completoPatel, Sunita I. "Exhaled breath nitric oxide is there a baseline difference due to ethnicity /". [Tampa, Fla.] : University of South Florida, 2005. http://purl.fcla.edu/fcla/etd/SFE0001156.
Texto completoAdisesh, Linganatha Anil. "Exhaled air nitric oxide and occupational exposure to organic dusts and endotoxin". Thesis, University of Manchester, 2003. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:86766.
Texto completoGordon, Robert L. "A comparison of exhaled breath nitric oxide between old and young individuals". [Tampa, Fla.] : University of South Florida, 2004. http://purl.fcla.edu/fcla/etd/SFE0000346.
Texto completoPatel, Sunita I. M. D. "Exhaled Breath Nitric Oxide: Is There A Baseline Difference Due To Ethnicity?" Scholar Commons, 2005. https://scholarcommons.usf.edu/etd/810.
Texto completoFranklin, Peter James. "The effect of indoor pollutants on exhaled nitric oxide in healthy children". Thesis, Franklin, Peter James (2000) The effect of indoor pollutants on exhaled nitric oxide in healthy children. PhD thesis, Murdoch University, 2000. https://researchrepository.murdoch.edu.au/id/eprint/52150/.
Texto completoBlake, Tamara Louise. "Spirometry and fractional exhaled nitric oxide (FeNO) reference values for Indigenous Australians". Thesis, Queensland University of Technology, 2019. https://eprints.qut.edu.au/131824/1/Tamara%20Blake%20Thesis.pdf.
Texto completoKeyser, Eric J. "Exhaled nitric oxide and the Systemic Inflammatory Response Syndrome (SIRS) after cardiac surgery". Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=31247.
Texto completoMethods. Forty-two intubated patients were studied postoperatively and at two-hour intervals for eight hours or until extubated. Hemodynamic indices, including indexed systemic vascular resistance (SVRi) and cardiac index (CI) were measured. ExNO was analyzed by ozone chemiluminescence.
Results. Six patients (14%) Manifested SIRS, defined as SVRI <1800 dynes·sec/cm5/m2. ExNO indexed by expired volume of minute ventilation and body surface area (exNO· V˙Ei) was less in SIRS patients at each interval. Overall, normal exNO·V˙Ei was 4.3 +/- 0.4 nL/min/m2 with a Cl of 2.56 +/- 0.05 L/min/m 2 and an SVRI of 2488 +/- 62 dynes·sec/cm5/m 2, whereas in SIRS exNO·V˙Ei was 0.7 +/- 0.3 (p < 0.001) with a Cl of 2.97 +/- 0.09 (p < 0.001) and an SVRi of 1826 +/- 86 (p < 0.001).
Conclusions. Pulmonary production of NO in post-CPB SIRS differs from sepsis and may not be reflective of systemic levels. Increased pulmonary blood flow may scavenge lung production of NO thereby decreasing exhaled levels.
Spanier, Adam Jason. "The Relationship of Genes and Environment with Exhaled Nitric Oxide in Children with Asthma". University of Cincinnati / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1204220355.
Texto completoArtlich, Andreas. "Nitric oxide in exhaled gas : studies on physiological regulation and measurements in infants and children /". Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3670-6/.
Texto completoGallagher, Michael James. "Evaluation of pulmonary function cross-shift changes in dairy parlor workers using spirometry & exhaled nitric oxide". Thesis, University of Iowa, 2013. https://ir.uiowa.edu/etd/1600.
Texto completoVento, Daniella Alves. "Desenvolvimento de um aparato para a coleta do condensado do exalado pulmonar visando a análise do óxido nítrico em indivíduos hígidos". Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/17/17137/tde-05082016-084941/.
Texto completoNitric oxide (NO) plays an important role in various physiological functions in the body and in various systems that compose it. It is known that this molecule is a normal constituent of exhaled breath in humans and animals. Its functions modulate inflammatory and immune responses as well as act in the regulation of vascular tone of smooth muscles of the airways. This molecule has been recognized as an important marker of lung injury, which sparked intense investigation of exhaled NO. A non-invasive method, low cost and easy application has been extensively studied to collect the exhaled air through its cooling and condensation, termed exhaled breath condensate. There is great interest in the study of inflammatory lung diseases, however, there is a considerable lack of evidence about the concentration levels of inflammatory mediators such NO in samples of healthy individuals using exhaled breath condensate. Given this, it was decided to develop a prototype apparatus for collecting exhaled breath condensate (EBC) and employ this technique to determine concentration values of nitric oxide in a sample of healthy volunteers. The sampling methodology based on the recommendations of the task force of the American Thoracic Society / European Respiratory Society (ATS / ERS) for procedures using for collection of condensate, in order to avoid methodological errors, standardize and bring more evidence to support the inclusion of the method in clinical routine, and make it available for further research. We selected 116 healthy adults of both gender, aged between 20 and 70. The prototype apparatus used in the research was designed, produced and developed in the Division of Thoracic and Cardiovascular Surgery, Faculty of Medicine, University of São Paulo-FMRP / USP. The commercial devices are all imported, expensive and not yet provided sufficient evidence that any of these would be the gold standard for collection. The apparatus was efficient to collect the EBC and NO was detectable in all samplesThe average NO was 14.4 ± 13 µM, and there was no correlation with gender (p = 0.847) and age (p = 0.811). There was no correlation between NO and the volume of collected EBC (p = 0.944). The volume of collected EBC is dependent on the total exhaled volume (p <0.001). From these results it can be seen that the apparatus is feasible and efficient. No correlation was found between the concentration of NO in the EBC, age and gender. The present study may contribute to future comparative studies of character and provide another option for apparatus for collecting condensate, providing low cost, reliability and reusability of the apparatus
Malinovschi, Andrei. "Nitric Oxide Exchange in Central and Peripheral Airways : Determinants in Health and Respiratory Disease". Doctoral thesis, Uppsala universitet, Institutionen för medicinsk cellbiologi, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9416.
Texto completoRoberts, Graham Colin. "The effects of allergic desensitisation on children with seasonal allergic asthma : symptom control and inflammation as measured by exhaled nitric oxide". Thesis, University of Oxford, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408813.
Texto completoWilson, Emma Elizabeth. "Biomarkers of airway inflammation : the use of exhaled nitric oxide (FeNO) in the management of adult asthma in UK primary care". Thesis, University of Nottingham, 2013. http://eprints.nottingham.ac.uk/29710/.
Texto completoBarath, Stefan, Nicholas L. Mills, Ellinor Ädelroth, Anna-Carin Olin y Anders Blomberg. "Diesel exhaust but not ozone increases fraction of exhaled nitric oxide in a randomized controlled experimental exposure study of healthy human subjects". Umeå universitet, Medicin, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-71312.
Texto completoAnderson, William James. "Personalising inhaled corticosteroid dose response in persistent asthma". Thesis, University of Dundee, 2016. https://discovery.dundee.ac.uk/en/studentTheses/0c7c79f5-91e8-4b47-96cd-69db4afc4cd8.
Texto completoAl-Badri, Faisal. "Assessing the health impact of intervention in supermarket bakeries using fractional exhaled nitric oxide (FeNO) and other clinical endpoints for baker’s allergy and asthma". Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29574.
Texto completoArcêncio, Livia. "Estudo do nitrito/nitrato no condensado do exalado pulmonar e no plasma de pacientes valvopatas e coronariopatas submetidos à cirurgia cardíaca com circulação extracorpórea". Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/17/17137/tde-28052018-154842/.
Texto completoPatients undergoing cardiothoracic surgery with cardiopulmonary bypass (CPB) have inflammatory reactions triggered by this procedure and by ischemia-reperfusion, which cause lung dysfunction and injury of vascular endothelium in the postoperative period. These processes related to cardiac surgery may affect the production and consumption of nitric oxide (NO) in the lung and vascular endothelium, especially in their participation in the inflammatory process. In the lung, NO diffuses easily and can be detected in the airway in the gas phase or in the lung fluid as nitrite and nitrate. The presence of NO in exhaled air may reflect the airway epithelium and lung microvascular endothelium in some situations. However, processes involving the production and consumption of NO in the airway are not totally understood. The exhaled breath condensate (EBC) is a fluid obtained by cooling exhaled air wich can be used for the investigation of NO in the distal airways. For this study we used an apparatus homemade and with low cost for collecting and obtain the EBC. The EBC was collected from patients with coronary artery disease and heart valve disease undergoing cardiac surgery with CPB in the preoperative and postoperative period (4 hours after CPB and 12, 24, 48 and 72 hours after extubation). Plasma concentrations of nitrite/nitrate in these patients were also evaluated using blood samples taken immediately after each collection of the EBC. The EBC and plasma were analyzed by chemiluminescence method to obtain the concentrations of nitrite/nitrate. The apparatus used was reproducible in clinical routine of cardiac surgery in patients under spontaneous ventilation or mechanical ventilation. There were no significant differences (p> 0.05) in concentrations of nitrite/nitrate in EBC and plasma in patients with coronary artery disease and heart valve disease in the preoperative period. Significantly higher concentrations of nitrite/nitrate (p=0.017) were found in EBC, but not in plasma of patients who used oral nitrate (isosorbide dinitrate) in the preoperative period. In patients who did not use medication containing NO donor (nitroglycerin or sodium nitroprusside) intravenously in the postoperative period there was a tendency to high concentrations of nitrite/nitrate in EBC that was numerically significant in the period of 48 hours postoperative (p=0.008). In patients who received or not NO donor in postoperative period the concentrations of nitrite/nitrate were significantly higher in periods of 48 hours (p=0.005) and 72 hours (p=0.037) after surgery. The use of nitroglycerin (GTN) in the postoperative period significantly elevated concentrations of nitrite/nitrate in the EBC in periods of 12 hours (p=0.022), 48 hours (p=0.015) and 72 hours (0.048) and plasma in period of 12 hours (p=0.045). The concentrations of nitrite/nitrate were significantly reduced (p=0.045) in the immediate postoperative period 4 hours after CPB in patients who received or not NO donor. From these results we could observe that there were no significant differences in concentrations of nitrite/nitrate in the EBC of patients with heart valve disease and coronary artery disease in the preoperative period, but we found a significant increase in these concentrations in patients who used isosorbide dinitrate orally. The concentrations of nitrite/nitrate in EBC presented a tendency to increase in postoperative period especially in patients who used GTN. The concentrations of nitrite/nitrate in plasma were significantly reduced after 4 hours of CPB in the immediate postoperative period. However, was observed that GTN tended to increase the concentration of nitrite/nitrate in plasma. These findings could help in future research providing comparative data about the role of NO in the airway and plasma in processes involving cardiac surgery in the pre and postoperative periods.
Sothirajah, Shobana. "Clinical Algorithms for Maintaining Asthma Control". Thesis, The University of Sydney, 2008. http://hdl.handle.net/2123/3546.
Texto completoSothirajah, Shobana. "Clinical Algorithms for Maintaining Asthma Control". University of Sydney, 2008. http://hdl.handle.net/2123/3546.
Texto completoRationale: Asthma management aims to achieve optimal control on the minimal effective dose of medication. We assessed the effectiveness of two algorithms to guide ICS dose in well-controlled patients on ICS+LABA in a double-blind study, comparing dose adjustment guided by exhaled nitric oxide (eNO) to clinical care algorithm(CCA) based on symptoms and lung function. Methods: We randomised non-smoking adult asthmatics on minimum FP dose 100μgs daily +LABA to ICS adjustment using eNO or CCA, assessed over 5 visits during 8 months treatment. Primary endpoints were asthma-free days and asthma related quality of life (QOL). Analysis was by mixed model regression and generalised estimating equations with log link. Results: 69 subjects were randomised (eNO:34, CCA:35) and 58 completed the study. At baseline mean FEV1 was 94% pred., mean eNO (200ml/sec) 7.1 ppb, median ACQ6 score 0.33. Median ICS dose was 500 μg (IQR 100-500) at baseline and 100 μg on both eNO (IQR 100-200) and CCA arms (IQR 100–100) at end of study. There were no significant differences between eNO and CCA groups in asthma-free days (RR=0.92, 95% CI 0.8–1.01), AQL (RRAQL
Alyousif, Zakaria A. "The Effects of High Intensity Interval Training (HIIT) on Asthmatic Adult Males". University of Toledo / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1403969461.
Texto completoGonçalves, Raquel Calvo. "Efeito do treinamento aeróbio na capacidade funcional, qualidade de vida, ansiedade, depressão e óxido nítrico exalado de adultos com asma persistente moderada ou grave". Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/5/5163/tde-16102014-101836/.
Texto completoThe aim of the present study was to evaluate the effect of aerobic training on quality of life, functional capacity and exhaled nitric oxide (NOex) in patients with moderate and severe asthma. Twenty nine subjects were randomly divided in control group (n 20) (educational program + breathing exercises) and training group (n 19) (control + aerobic training, 70% maximal VO2peak) and followed during 3 months, twice a week. Aerobic capacity (VO2peak), quality of life, anxiety, depression, and pulmonary function were evaluated before and after treatment. FENO and symptoms were evaluated monthly. There was no change in inhaled glucocortiscosteroid during treatment. Our results show that patients submitted to an aerobic training presented a decrease on physical limitation (p < 0.05), frequency and gravity score, decrease in psychosocial limitation an increse in global score of quality of life (p < 0.05) as well as an improvement on VO2peak (p=0,001) when compared with control group. Compared with control group, training group also presented a increase in number of days without symptoms (p < 0,001). FENO it was also decreased (p < 0,001) after training in training group. No change was observed in lung function in both groups after treatment. Our results suggest that aerobic improves quality of life and decreases symptoms and exhaled nitric oxide on asthmatic patients reinforcing its importance on asthma treatment
Correia, Iolanda Baptista Gonçalves Caires. "Influência do ciclo menstrual na fracção exalada de óxido nítrico". Master's thesis, Faculdade de Ciências Médicas. Universidade Nova de Lisboa, 2011. http://hdl.handle.net/10362/6987.
Texto completoSingh, Umesh M. D. "Environmental Exposures to Airborne Microbial Sub-micrometer Particles and Airway Inflammation in Children". University of Cincinnati / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1318607732.
Texto completoRonkainen, E. (Eveliina). "Early risk factors influencing lung function in schoolchildren born preterm in the era of new bronchopulmonary dysplasia". Doctoral thesis, Oulun yliopisto, 2016. http://urn.fi/urn:isbn:9789526213477.
Texto completoTiivistelmä Keskosten tehohoito on kehittynyt viime vuosikymmeninä merkittävästi, ja yhä epäkypsempänä syntyvät keskoset selviävät hengissä syntymän jälkeen. Keskosten pitkäaikainen keuhkosairaus, bronkopulmonaalinen dysplasia (BPD), on perinteisesti johtunut hengityskonehoidon ja happikaasun aiheuttamasta keuhkovauriosta ja johtanut keuhkokudoksen arpeutumiseen. Aiempaa ennenaikaisemmilla keskosilla esiintyy kuitenkin nykyään niin sanottua uutta BPD:tä, jonka ajatellaan johtuvan enemmän keuhkorakkuloiden kehityshäiriöstä kuin hoitojen aiheuttamasta keuhkovauriosta. Selvitimme, miten nykyaikaisilla menetelmillä hoidettujen keskosten keuhkojen rakenne ja toiminta kehittyvät kouluikään mennessä. Seurantatutkimukseemme osallistui 88 ennenaikaisena syntynyttä, kouluikään ehtinyttä lasta ja 88 täysiaikaisena syntynyttä, kaltaistettua verrokkia. Keskosena syntyneiden lasten keuhkofunktio oli kouluiässä huonompi kuin täysiaikaisena syntyneiden verrokkien. Alhaisin keuhkofunktio oli niillä keskosena syntyneillä lapsilla, jotka olivat sairastaneet vastasyntyneenä BPD:n. Myös kohdunsisäiseen kasvuhäiriöön (intrauterine growth restriction, IUGR) liittyi alentunut keuhkofunktio. BPD ja IUGR ennustivat alentunutta keuhkofunktiota toisistaan riippumatta. Tutkimuksessa tehtiin myös keuhkojen ohutleiketietokonekuvaus 21 keskoselle, jotka olivat sairastaneet BPD:n. Lähes kaikilla havaittiin poikkeavia löydöksiä – eniten niillä, joilla oli ollut vastasyntyneenä BPD:n vaikea tautimuoto. Keskosina syntyneet joutuivat kahden ensimmäisen vuoden aikana verrokkeja useammin sairaalahoitoon. Yleisimpiä syitä olivat hengityksen vinkumista aiheuttavat taudit kuten ilmatiehyttulehdus, ahtauttava keuhkoputkitulehdus tai akuutti astmakohtaus. Vastasyntyneenä sairastettu BPD ei kuitenkaan lisännyt todennäköisyyttä joutua sairaalahoitoon. Tutkimuksessa tehtiin myös meta-analyysi nykyaikaisilla menetelmillä hoidettujen keskosten keuhkofunktiosta: lievää BPD:tä sairastavien tulokset näyttävät parantuneen, kun taas keskivaikeaa tai vaikeaa tautimuotoa sairastavien ja ilman BPD:tä selvinneiden keuhkofunktio ei ole muuttunut uusien hoitojen myötä. Yhteenvetona voidaan todeta, että keskosten keuhkojen toimintakyky on jonkin verran alentunut täysiaikaisiin verrattuna. Lievästi alentunut keuhkofunktio ei kuitenkaan yleensä aiheuttanut koululaisille oireita. Keskosena syntyneiden lasten hengityselinten toimintaa on syytä seurata, sillä niin sanotun uuden BPD:n pitkäaikaisesta ennusteesta ei ole vielä tietoa
"Exhaled nitric oxide in Chinese schoolchildren". 2005. http://library.cuhk.edu.hk/record=b5896396.
Texto completoThesis (M.Phil.)--Chinese University of Hong Kong, 2005.
Includes bibliographical references (leaves 88-98).
Abstracts in English and Chinese.
Abstract (in English) --- p.i
Abstract (in Chinese) --- p.iii
Acknowledgement --- p.v
Table of Contents --- p.vi
List of Tables --- p.ix
List of Figures --- p.x
Glossary of Terms and Abbreviations --- p.xi
Chapter Section I: --- Overview --- p.1
Chapter Chapter 1: --- Introduction --- p.2
Chapter 1.1 --- Asthma and Assessment of A irway Inflammation --- p.2
Chapter 1.1.1 --- Assessment of A irway Inflammation --- p.4
Chapter 1.1.2 --- Invasive and Noninvasive Methods --- p.4
Chapter 1.1.3 --- Exhaled Nitric Oxide as a Diagnostic Marker and Its Correlation with Other Markers of Inflammation --- p.6
Chapter 1.1.4 --- Normal Reference Studies of Exhaled Nitric Oxide --- p.8
Chapter 1.2 --- Aim of Study --- p.10
Chapter Chapter 2: --- Plan of Study --- p.11
Chapter Section II: --- Literature Review --- p.13
Chapter Chapter 3: --- Nitric Oxide Biology --- p.15
Chapter 3.1 --- Exhaled Nitric Oxide Production in Airway --- p.15
Chapter 3.2 --- Nitric Oxide Production and Function --- p.16
Chapter 3.3 --- Nitric Oxide Synthase Pathway --- p.18
Chapter 3.4 --- Factors Affecting Exhaled Nitric Oxide Level --- p.21
Chapter 3.4.1 --- Procedure-related Factors --- p.22
Chapter 3.4.1.1 --- Nasal Nitric Oxide Contamination --- p.22
Chapter 3.4.1.2 --- Exhalation Procedure 226}0´ؤؤStarting Lung Volumes --- p.23
Chapter 3.4.1.3 --- Exhalation Procedure 226}0ؤ Flow --- p.23
Chapter 3.4.1.4 --- Circadian Rhythm --- p.25
Chapter 3.4.2 --- Patient Factors --- p.26
Chapter 3.4.2.1 --- Sex --- p.26
Chapter 3.4.2.2 --- Upper Respiratory Tract Infection --- p.26
Chapter 3.4.2.3 --- Diet and Exhaled Nitric Oxide --- p.27
Chapter 3.4.2.4 --- Effect of Spirometry and Exercise --- p.28
Chapter 3.4.3 --- Environmental Factors --- p.28
Chapter Chapter 4: --- Exhaled Nitric Oxide in Asthmatics and Its Relationship to Anti-inflammatory Treatment --- p.31
Chapter Chapter 5: --- Relationship of Exhaled Nitric Oxide with Other Inflammatory Markers --- p.33
Chapter 5.1 --- Correlation of Findings from Biopsy and Bronchoalveolar Lavage with Exhaled Nitric Oxide --- p.33
Chapter 5.2 --- "Exhaled Nitric Oxide, Induced Sputum Analysis and Sputum Eosinophil Cationic Protein" --- p.35
Chapter Section III: --- Original Study --- p.37
Chapter Chapter 6: --- Methodology --- p.38
Chapter 6.1 --- Study Population --- p.38
Chapter 6.2 --- The International Study of Asthma and Allergies in Childhood --- p.40
Chapter 6.3 --- ISAAC Questionnaires --- p.42
Chapter 6.4 --- Standardized Approach for Answering Questions in the Field --- p.44
Chapter 6.5 --- Anthropometric Measurements --- p.45
Chapter 6.6 --- Exhaled Nitric Oxide Measurement --- p.46
Chapter 6.6.1 --- "NIOY® (Aerocrine AB, Stockholm, Sweden)" --- p.46
Chapter 6.6.2 --- Calibration Procedures --- p.47
Chapter 6.6.3 --- Exhaled Nitric Oxide Measurement --- p.48
Chapter 6.7 --- Classification of Subjects --- p.51
Chapter 6.8 --- Statistical Analysis --- p.53
Chapter Chapter 7: --- Results --- p.54
Chapter 7.1 --- Subjects and Demography --- p.54
Chapter 7.2 --- Exhaled Nitric Oxide in Chinese Children --- p.58
Chapter 7.3 --- Exhaled Nitric Oxide in Caucasians and Other Ethnic Groups --- p.66
Chapter Chapter 8: --- Discussion --- p.69
Chapter Chapter 9: --- Conclusion and Further Studies --- p.76
Appendix 1 Questionnaires (Chinese Version) --- p.80
Appendix 2 Questionnaires (English Version) --- p.84
References --- p.88
Paz, Miguel Ángel. "Fractional exhaled nitric oxide in pulmonary hypertension". Thesis, 2018. https://hdl.handle.net/2144/31263.
Texto completoJacinto, Tiago António Queirós. "Important determinants and reference values for exhaled nitric oxide". Doctoral thesis, 2017. https://repositorio-aberto.up.pt/handle/10216/104198.
Texto completoJacinto, Tiago António Queirós. "Important determinants and reference values for exhaled nitric oxide". Tese, 2017. https://repositorio-aberto.up.pt/handle/10216/104198.
Texto completoByrnes, Catherine Ann. "Non-invasive method of measuring airway inflammation : exhaled nitric oxide". 2008. http://hdl.handle.net/2292/5558.
Texto completoHsieh, Chun-Fa y 謝泉發. "Effect of Air Pollution on Exhaled Nitric Oxide Levels in Schoolchildren". Thesis, 1999. http://ndltd.ncl.edu.tw/handle/27888139108348174361.
Texto completo國立陽明大學
公共衛生研究所
87
Asthma is a chronic inflammatory disease of the airway. Recently, studies have found that exhaled nitric oxide (eNO) was correlated with airway inflammation. We used eNO measurement and questionnaire to clarify the effect of air pollution on asthma and airway disease in schoolchildren. Our study subjects were third grade students from 石牌國小 in Taipei and 淡水國小 in Tamshui. We recruited 256 students (male: 133, female: 123) from the two schools. Study was performed between October 1998 and Apr 1999. The effect of children''s atopy or airway disease on eNO, and the effect of air pollutants and children''s eNO were analyzed. Finally, We compared the effect of air pollutants on children with or without atopic airway disease. In the study subjects, 10.2% children had physician-diagnosed asthma, 19.1% children had wheezing, 24.6% children had physician-diagnosed allergic rhinitis, and 5.4% children had physician-diagnosed dermatitis. Family factors that influenced eNO: children''s father with higher education, mother with allergic rhinitis, and sibling with allergic rhinitis would increase children''s eNO level. Children''s factors affecting eNO included: physician-diagnosed asthma, wheeze, allergic rhinitis, dermatitis, cough in the past year, and upper airway infection (at the time of examination) would increase children''s eNO level. Air pollution: Ozone concentration, ambient temperature, and particulate matter would decrease eNO level, but ambient nitric oxide concentration would increase eNO level. We also found that eNO level was continually increasing from October 1998 to Mar 1999. And it was decreased from Mar 1999 to Apr 1999. URI, sulfur dioxide, and particulate matter had more pronounced effect on nonatopic students. We also found that atopic students were more sensitive to ambient temperature. We concluded that atopy, airway disease and air pollution were correlated with eNO. The most important factor in air pollution that influenced children''s eNO was ambient temperature. We also found that eNO had a time-dependent trend. In conclusion, ozone concentration, ambient temperature, ambient nitric oxide, URI, and allergic rhinitis were important on eNO level.
Sheel, Andrew William. "Relationship between exhaled and inhaled nitric oxide and exercise-induced hypoxemia". Thesis, 1999. http://hdl.handle.net/2429/10904.
Texto completoHUANG, SHIH-TING y 黃詩婷. "Association of exposure to welding fume particulates with plasma nitric oxide and fractional exhaled nitric oxide among shipyard workers". Thesis, 2018. http://ndltd.ncl.edu.tw/handle/jpcq9t.
Texto completo國防醫學院
公共衛生學研究所
106
Aim: We assessed the relations between heavy metals, polycyclic aromatic hydrocarbons exposure and plasma nitric oxide, fractional exhaled nitric oxide, and lung function among shipyard workers. Methods: This study was a longitudinal study. All of 354 workers were recruited from the shipyard in Taiwan from 2014 to 2016. After excluded female workers, there were 333 workers include in this study finally. Personal air sampling was collected at the first day; FeNO and lung function test were collected at the second day. In order to analyze urine heavy metals and plasma NO, we also collected blood and urine from workers in both days. Results: In generalized estimating equation analysis, adjusting for age, waist, smoking status, time, and urinary creatinine, negative significant were found between log urinary nickel and log plasma NO (β=-0.079, 95%CI: -0.149 to -0.009, p=0.026). After adjusting for age, waist, smoking status, and time, negative significant were found between log PM2.5 and log FeNO (β=-0.051, 95%CI: -0.087 to -0.016, p=0.004). After adjusting for age, waist, smoking status, time, and urinary creatinine, negative significant were found between log urinary manganese and log FeNO (β=-0.068, 95%CI: -0.13 to -0.006, p=0.032); negative significant were found between log urinary cadmium and log plasma NO (β=-0.133, 95%CI: -0.221 to -0.045, p=0.003); negative significant were found between log urinary 1-OHP and log FeNO (β=-0.123, 95%CI: -0.233 to -0.014, p=0.028); negative significant were found between log urinary nickel and FVC% (β=-20.015, 95%CI: -34.836 to -5.194, p=0.008); FEV1 % (β=-19.159, 95%CI: -32.079 to -6.239, p=0.004); FEV1/FVC % (β=-1.983, 95%CI: -3.898 to -0.067, p=0.043). Conclusion: In conclusion, this study showed biomarkers of exposure to Mn, Cd, Ni, and PAH are associated with decreased plasma NO, FeNO, and lung function indicators. We suggest to wearing personal protective equipment may decrease adverse health effects from occupational exposure.
KUO, Yi-Chieh y 郭怡潔. "Effect of Betel (Areca) Nut Chewing on Fractional Exhaled Nitric Oxide Levels". Thesis, 2015. http://ndltd.ncl.edu.tw/handle/08624855852381512931.
Texto completo中州科技大學
保健食品系
103
Background:Betel nut chewing is common in Taiwan and exhaled nitric oxide (eNO) is most important in our heath. It is make vessel dilatation to adjust blood pressure in cardiac vascular system. To control coagulation and cardiac contraction function. The peripheral nerve system can adjust vessel dilatation, respiratory, digestive and urological function with penis erection. In the immune system against bacteria, cancer cells and other pathogens, kill a variety of pathogens and protection mechanisms, and can provide a powerful defense system in vivo. Studies published in a patient suffering from asthma increased exhaled nitric oxide concentrations in the air in 1993, but if the patient has to take steroid drugs to reduce the concentration of exhaled nitric oxide. With so many articles when studies show respiratory irritation detect exhaled nitric oxide concentration, the concentration was found to increase nitric oxide can induce inflammatory inference eosinophil activity sphere. It is not known whether betel nut chewing affects eNO with contains constituents known to inhibit inducible NO synthase which releases exhaled. May be associated with respiratory inflammation related to this study will help to understand the impact of chewing betel nut of the human immune defense mechanism. Objective:To assess the effects of betel nut chewing on eNO levels. Methods:Nineteen regular betel nut chewers were studied. eNO levels were measured using a portable analyser (MiniNIOX) prior to and immediately after chewing a betel nut preparation, and at 30 min intervals up to 3 hr. Results:Data analysis and display chew whether fractional exhaled nitric oxide concentration (FeNO Value) will cause respiratory irritation reaction before and after the betel nut, exhaled nitric oxide in each group, are no significant differences. Whether the instrument detects lung function FEV1 (L) can cause airway contractile response in each group, are no significant differences. The possible reasons: 1. regional betel different contents of its relevance. 2. Oral cancer is not through this oncogenic pathway for inflammation. 3. Cha Ye component having polyphenolic compounds with antioxidant activity activity, further inhibit inflammation. Conclusions and Clinical Relevance:In this study, chewing betel nut, after their respiratory exhaled nitric oxide concentration FEV1 testing and data analysis, the results showed no statistical significance, followed by studies can then be blood test specific immunoglobulin E (Allergen Specific -IgE) data, the relative analysis of betel nut chewing further estimate whether the subjects of their respiratory inflammation, in order to facilitate the clinical diagnosis as the reference data.
Holland, Ben Patrick. "Measurement of exhaled nitric oxide and carbon dioxide in the breath of beef calves". 2006. http://digital.library.okstate.edu/etd/umi-okstate-1956.pdf.
Texto completoFang, Chun-Yu y 方俊淯. "A Study of the Associations Between Air Pollutants Exposure and Exhaled Nitric Oxide / Exhaled Breath Condensate pH in Schoolchildren with Asthma". Thesis, 2007. http://ndltd.ncl.edu.tw/handle/8236x7.
Texto completo輔仁大學
公共衛生學系碩士班
96
Background: According to the epidemiological studies, it demonstrated that the prevalence and incidence rate of asthma were increasing gradually every year. People spent over 80 % of their time indoors. Indoor and outdoor air pollutants such as particular matter(PM), volatile organic compounds(VOCs), sulfur dioxide(SO2), ozone(O3)had been proved to be significantly correlated with the increased incidence of respiratory symptoms in asthmatic children. Collection of exhaled gas was a simple and noninvasive technique for sampling of nitric oxide(NO)and airway lining fluid that can be used as indicators of exacerbation of respiratory diseases. This study was to evaluate the impaction of indoor and outdoor air pollutants on pulmonary function by measuring NO levels and exhaled breath condensate(EBC)pH in exhaled gas. Methods: This panel study recruited 15 asthmatics and 15 healthy children, aged between 7 and 12 years old, from outpatient department of Chang Gung Memorial Hospital in 2006. Self-reported questionnaires included personal information, family allergic history, blood allergy index, and home/life characteristics. Air quality in domestic environment was measured with the dust monitor(GRIMM particle size analyzer model l.108, Germany), air quality monitor(I.A.Q, KD Engineerings AirBoxx, USA), and VOCs monitor(ppbRAE, RAE Systems model PGM-7600, USA). Exhaled NO levels in schoolchildren were monitored by a chemiluminescence analyzer (CLD 77 AM, ECO Physics, Dürnten, Switzerland). EBC pH was analyzed after collecting EBC from subjects using an exhaled breath condensate collector(ECoScreen, Jaeger-Toennies, Germany). Pulmonary function tests were performed every three months to evaluate the variation of lung functions. The concentrations of outdoor air pollutants measured at the ambient air monitoring site operated by Taiwan Environmental Protection Agency(EPA)that located in district of Songshan were also collected. All the data were analyzed by SPSS software. Result: This study was to monitor indoor air quality of domestic environment in schoolchildren with asthma and healthy controls in autumn and winter. Air temperature in domestic environment of asthmatics was higher than the recommended value of indoor air quality guideline. Our results demonstrated that mean eNO concentrations in asthmatics(41.62 ppb in autumn and 48.75 ppb in winter)were significantly higher than those in healthy individuals(14.90 ppb in autumn and 14.94 ppb in winter)( p=0.001 in autumn and p<0.001 in winter). There was not a statistically significant difference in EBC pH between asthmatics(pH=6.76 in autumn and 6.61 in winter)and healthy children (pH=7.12 in autumn and 6.82 in winter) ( p=0.112 in autumn and p=0.412 in winter), but EBC pH had a lower tendency found in children with asthma than normal controls in this study. In addition, forced expiratory volume time on one second (FEV1), peak expiratory flow (PEF) and forced expiratory flow25% ~ 75%, (FEF25% ~ 75%) in asthmatics had a decreased trend compared to healthy controls in both autumn and winter. From our findings, it was indicated that air pollutants were associated with eNO level, EBC pH and pulmonary function test. NO association was found between eNO level and EBC pH in schoolchildren. Conclusion: Exhaled gas analysis is a noninvasive, duplicated, and safety monitoring technique. Measurements of exhaled NO and EBC pH would react with airway inflammation correlated to indoor and outdoor air pollutants exposure.
Chu, Chia-Chen y 朱家成. "The Clinical Application of Chemiluminesce method - The Measurement of the Asthmatic Patients'' Exhaled Nitric Oxide Concentration". Thesis, 1999. http://ndltd.ncl.edu.tw/handle/27858948097004613452.
Texto completo中國文化大學
應用化學研究所
87
Nitric oxide (NO) can be detected in the exhaled air of humans. Several recent studies have demonstrated that the concentration of exhaled NO is increased in patients with asthma, but reduced after patients were treated with inhaled glucocorticoids. In this thesis, we would like to build up a data bank and a method for measurement of exhaled NO concentrations of asthmatic patients in Taiwan. Exhaled NO determinations were performed via a on-line restricted exhaled breath method in 57 normal and 82 asthmatic subjects by a chemiluminescence analyzer. The exhaled NO level in the normals was 16.4 * 6.7 ppb, while the levels in the asthmatics, before and after treated with an inhaled bronchodilator, were 32.1 * 27.6 and 30.3 * 11.4 ppb, respectively. Obviously, the exhaled NO concentrations determined in patients with asthma were significantly elevated above those of normal subjects. However, there was no statistically significant change ( p > 0.05 ) in NO contents of asthmatic paitents, before and right after treated with a bronchodilator, no matter what age, sex, or level of exhaled NO. It is known that the difference in exhaled NO of normal subjects and asthmatics derives from a difference in NO concentration present in the lower airway, and reflects the inflammatory microenvironment of the asthmatic airway wall. Thus, the measurement of nitric oxide concentrations in exhaled air may represent a noninvasive measure of lower airway inflammation. And, it will be a useful way of monitoring the anti-inflammatory effects of glucocorticoids and other anti-inflammatory treatments in asthma.
Hsu, Jeng-Yuan y 許正園. "Non-invasive Monitoring of Airway Inflammation Evaluation by Exhaled Nitric Oxide in Patients with Chronic Airway Disease". Thesis, 2013. http://ndltd.ncl.edu.tw/handle/10667325543853123359.
Texto completo中山醫學大學
醫學研究所
101
Objective: To evaluation the usefulness of FeNO measurement in patients with eosinophilic inflammatory airway disease, such as bronchial asthma and chronic cough. Material and Method: A nitric oxide analyzer (NOA 280i) was used to conduct five experiments. In the first experiment, 249 Taiwanese non-smoking healthy adults were enrolled to determine the reference values of FeNO in Taiwan. In the second experiment, the correlations between offline and online FeNO data of 56 patients were evaluated. In the third experiment, the correlations between FeNO level and % of major basic protein (MBP) positive sputum cells (eosinophils) were compared. In the fourth experiment, we investigated possible correlations between ACT scores and FeNO values in 73 outpatient visits made by 60 asthmatic patients. In the fifth experiment we reviewed the medical records of 81 patients with chronic cough, to compare the FeNO level and the response to inhaled corticosteroid treatment in these patients. Results: The result of the first experiment showed that the mean FeNO in 249 Taiwanese non-smoking healthy adults was 27.9ppb. In multivariate regression analyses, age and lung function (FVC or FEV1) were positively associated with the FeNO values. In the second experiment, a high correlation between online and offline FeNO levels (r = 0.908, p < 0.001) were observed. The predicted online FeNO level (ppb) = 2.233 × offline FeNO level (ppb) - 6.236. In the third experiment, no correlation between FeNO level and percentage of major basic protein (MBP) positive sputum cells (eosinophils) were seen, but in 19 and 16 patients, the % of MBP positive cells was higher than 3% and 5% respectively. The result of the fourth experiment showed the mean FeNO value was higher in patients reported their ACT scores were≧20 than those who reported the ACT scores were<20. There was a negative correlation between ACT scores and FeNO values (r = -0.596). In the fifth experiment, significant difference in FeNO value was seen in patients whose cough responded good to ICS treatment.ROC analysis showed that a FeNO of 33.9 ppb was the best cut-off value for using ICS (sensitivity 94.7%, specificity 76.3%). Conclusions: After conducting these five experiments, we found that FeNO measurement is a versatile, easy-to-use, non-invasive diagnostic tool for assessing inflammatory airway diseases. By using the reference FeNO value and the formula for predicting online data that we have devised, FeNO measurement can be applied to patients for evaluating eosinophilic inflammation of the airways.
"The acute effects of high intensity interval exercise on pulmonary function and exhaled nitric oxide in adults with asthma". Thesis, 2014. http://hdl.handle.net/10388/ETD-2014-08-1707.
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