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1

Taegtmeyer, Heinrich y Saumya Sharma. "Anemia and energy depletion". Journal of the American College of Cardiology 42, n.º 11 (diciembre de 2003): 2030. http://dx.doi.org/10.1016/j.jacc.2003.09.012.

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2

Stokes, Bradford T., Ruth A. Altschuld, Charlene M. Hohl, Qian Li y Douglas K. Anderson. "Energy depletion in culture". Molecular and Chemical Neuropathology 15, n.º 1 (agosto de 1991): 29–35. http://dx.doi.org/10.1007/bf03161054.

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3

Béjar, Alejandro Alvarez. "Energy, Integration, and Resource Depletion". NACLA Report on the Americas 47, n.º 1 (enero de 2014): 32–34. http://dx.doi.org/10.1080/10714839.2014.11721868.

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4

Mozaffarian, Dariush y Wayne Levy. "Anemia and energy depletion: reply". Journal of the American College of Cardiology 42, n.º 11 (diciembre de 2003): 2030. http://dx.doi.org/10.1016/j.jacc.2003.09.013.

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5

Watanabe, Hiroshi, Rolf Spahr y H. Michael Piper. "Endothelial macromolecule permeability under energy depletion". Journal of Molecular and Cellular Cardiology 22 (mayo de 1990): S8. http://dx.doi.org/10.1016/0022-2828(90)91553-j.

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6

Francis, Zoë, Marina Milyavskaya, Hause Lin y Michael Inzlicht. "Development of a Within-Subject, Repeated-Measures Ego-Depletion Paradigm". Social Psychology 49, n.º 5 (septiembre de 2018): 271–86. http://dx.doi.org/10.1027/1864-9335/a000348.

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Abstract. Ego depletion is under scrutiny for low replicability, possibly reflecting the limited statistical power available in between-subject designs. In response, we created a within-subject, repeated-measures ego-depletion paradigm that repeatedly alternated depletion and recovery manipulations. Each manipulation was followed by measuring subjective fatigue, mood, and self-control performance. Across 12 studies (N = 754), participants reliably reported having lower energy and mood after depleting manipulations compared to after recovery manipulations. Depletion manipulations did not consistently affect behavioral self-control, although the depletion effect was meta-analytically significant (d = .045). Furthermore, unintended fatigue and practice effects occurred over the course of the paradigm, systematically interfering with the intended depletion effects. We recommend that depletion research takes advantage of within-subject designs across multiple sessions to avoid spillover effects between measurements.
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7

Hossain, Mohammad Razib, Sanjeet Singh, Gagan Deep Sharma, Simona-Andreea Apostu y Pooja Bansal. "Overcoming the shock of energy depletion for energy policy? Tracing the missing link between energy depletion, renewable energy development and decarbonization in the USA". Energy Policy 174 (marzo de 2023): 113469. http://dx.doi.org/10.1016/j.enpol.2023.113469.

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8

Falcone, Giusy y Zachary R. Putnam. "Energy Depletion Guidance for Aerobraking Atmospheric Passes". Journal of Guidance, Control, and Dynamics 45, n.º 4 (abril de 2022): 651–68. http://dx.doi.org/10.2514/1.g006171.

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9

Gardner, Ann y Richard G. Boles. "Mitochondrial Energy Depletion in Depression with Somatization". Psychotherapy and Psychosomatics 77, n.º 2 (2008): 127–29. http://dx.doi.org/10.1159/000112891.

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10

Ashrafian, Houman, Charles Redwood, Edward Blair y Hugh Watkins. "Hypertrophic cardiomyopathy:a paradigm for myocardial energy depletion". Trends in Genetics 19, n.º 5 (mayo de 2003): 263–68. http://dx.doi.org/10.1016/s0168-9525(03)00081-7.

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11

Spencer, Paul. "Oil depletion". Refocus 5, n.º 5 (septiembre de 2004): 3. http://dx.doi.org/10.1016/s1471-0846(04)00196-9.

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12

Yu, Jiankai y Benoit Forget. "Verification of depletion capability of OpenMC using VERA depletion benchmark". Annals of Nuclear Energy 170 (junio de 2022): 108973. http://dx.doi.org/10.1016/j.anucene.2022.108973.

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13

Sokoloff, Louis. "Energy Metabolism and Effects of Energy Depletion or Exposure to Glutamate". Canadian Journal of Physiology and Pharmacology 70, S1 (15 de mayo de 1992): S107—S112. http://dx.doi.org/10.1139/y92-251.

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The entire program of the first day of the IBRO satellite meeting entitled Ions, Water, and Energy in Brain Cells was devoted to the subject of energy. There were three sessions on the topics of energy metabolism, activation, and development and pathological conditions, followed by a final general discussion on the contents of the day's topics. During this general discussion there were spirited exchanges on the role of glycogen in the energy metabolism of the brain, on the metabolic source of the energy consumed by functional activity, e.g., glycolytic or oxidative energy metabolism, and on the sources of the acid-equivalents that are responsible for the tissue acidosis accompanying cerebral hypoxia. Despite the arguments pro and con presented on all of the issues that were discussed, it is doubtful that a consensus was achieved on most of the issues.Key words: glycogen, glycolysis, oxidative metabolism, acidosis, energy metabolism.
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14

Alkhateeb, Tarek Tawfik Yousef y Haider Mahmood. "Oil Price and Energy Depletion Nexus in GCC Countries: Asymmetry Analyses". Energies 13, n.º 12 (12 de junio de 2020): 3058. http://dx.doi.org/10.3390/en13123058.

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Oil price has played a prominent role in oil exporter economies and may also affect energy depletion in oil-dependent countries. Considering asymmetry, the relationship between oil price (OP) and energy depletion has been investigated in the Gulf Cooperation Council (GCC) region from 1970 to 2017. We find asymmetrical positive effects of OP on the energy depletion in the panel of the GCC region. To avoid aggregation biasness in the panel estimates, we also conduct a time-series analysis on each GCC country. We find a positive impact of increasing OP on the energy depletion in six GCC countries, and this effect is found to be elastic in the case of all countries except for Kuwait. Positive effects of decreasing OP on the depletion are also found in all the GCC countries, and these effects are found to be elastic or unit elastic in the case of all countries except Saudi Arabia. Asymmetry in the relationship of oil price and energy depletion is established for Bahrain, Kuwait, and Saudi Arabia in terms of the different magnitude of effects.
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15

Kandpal, Rohan y Rajendra Singh. "Renewable Energy Sources – A Review". ECS Transactions 107, n.º 1 (24 de abril de 2022): 8133–40. http://dx.doi.org/10.1149/10701.8133ecst.

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The development of technology combined with the surge in population has led to a new era of living that has increased energy demand. Fossil fuel has been the main energy source for so many years, but it is no longer sustainable with its depletion and negative consequences. A need has arisen for a replacement resource to replace the depleting fossil fuels using right now. This need is what pushes us towards renewable energy. An examination of renewable energy sources: their uses, potentials, and limitations, as well as their effects on the climate and human health, is presented in this work. As final recommendations, the paper outlines policies and strategies to address climate change and fully integrate renewables as a sustainable energy source.
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16

Lee, Bonggi, Liping Qiao, Brice Kinney, Gen-Sheng Feng y Jianhua Shao. "Macrophage Depletion Disrupts Immune Balance and Energy Homeostasis". PLoS ONE 9, n.º 6 (9 de junio de 2014): e99575. http://dx.doi.org/10.1371/journal.pone.0099575.

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17

Shadwick, B. A., C. B. Schroeder y E. Esarey. "Nonlinear laser energy depletion in laser-plasma accelerators". Physics of Plasmas 16, n.º 5 (mayo de 2009): 056704. http://dx.doi.org/10.1063/1.3124185.

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18

Lowry, C. W., T. M. Brennan y B. G. Hammons. "Pump depletion through coherent energy transfer in semiconductors". Optics Letters 20, n.º 2 (15 de enero de 1995): 127. http://dx.doi.org/10.1364/ol.20.000127.

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19

Goldberg, Emily L. y Vishwa Deep Dixit. "Bone Marrow: An Immunometabolic Refuge during Energy Depletion". Cell Metabolism 30, n.º 4 (octubre de 2019): 621–23. http://dx.doi.org/10.1016/j.cmet.2019.08.022.

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20

Bronisz, Agnieszka, E. Antonio Chiocca y Jakub Godlewski. "Response to energy depletion: miR-451/AMPK loop". Oncotarget 6, n.º 20 (23 de junio de 2015): 17851–52. http://dx.doi.org/10.18632/oncotarget.4606.

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21

Marini, Guendalina, Elisabeth Nüske, Weihua Leng, Simon Alberti y Gaia Pigino. "Reorganization of budding yeast cytoplasm upon energy depletion". Molecular Biology of the Cell 31, n.º 12 (1 de junio de 2020): 1232–45. http://dx.doi.org/10.1091/mbc.e20-02-0125.

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Yeast responds to energy depletion with a rapid cytoplasmic reorganization that includes cytosol compaction and de novo formation of membraneless compartments. The reversible polymerization of eIF2B into filamentous assemblies suggests a mechanism of translational control that allows cells to move quickly back and forth between response states.
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22

Nguyen, Van-Linh, Po-Ching Lin y Ren-Hung Hwang. "Energy Depletion Attacks in Low Power Wireless Networks". IEEE Access 7 (2019): 51915–32. http://dx.doi.org/10.1109/access.2019.2911424.

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23

Kobayashi, Takashi, Malcolm K. Robinson, Vickye Robinson, Eve Derosa, Douglas W. Wilmore y Danny O. Jacobs. "Glutathione Depletion Alters Hepatocellular High-Energy Phosphate Metabolism". Journal of Surgical Research 54, n.º 3 (marzo de 1993): 189–95. http://dx.doi.org/10.1006/jsre.1993.1030.

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24

Oda, Teiji, Tetsuhiro Kimura, Yoshitaka Ogata y Yutaka Fujise. "Optimized retrograde cerebral perfusion reduces ischemic energy depletion". Journal of Artificial Organs 7, n.º 1 (1 de marzo de 2004): 19–26. http://dx.doi.org/10.1007/s10047-003-0247-3.

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25

Pinson, Arié, Régine Tirosh, Victoria Trembovler y Esther Shohami. "Energy depletion triggers eicosanoid synthesis in cultured myocytes". Journal of Molecular and Cellular Cardiology 24 (mayo de 1992): 197. http://dx.doi.org/10.1016/0022-2828(92)90616-8.

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26

Porkka-Heiskanen, Tarja, Anna Kalinchuk, Lauri Alanko, Anna Urrila y Dag Stenberg. "Adenosine, Energy Metabolism, and Sleep". Scientific World JOURNAL 3 (2003): 790–98. http://dx.doi.org/10.1100/tsw.2003.65.

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While the exact function of sleep remains unknown, it is evident that sleep was developed early in phylogenesis and represents an ancient and vital strategy for survival. Several pieces of evidence suggest that the function of sleep is associated with energy metabolism, saving of energy, and replenishment of energy stores. Prolonged wakefulness induces signs of energy depletion in the brain, while experimentally induced, local energy depletion induces increase in sleep, similarly as would a period of prolonged wakefulness. The key molecule in the induction of sleep appears to be adenosine, which induces sleep locally in the basal forebrain.
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27

Khalatov, A. A., N. M. Fialko y M. P. Tymchenko. "ENERGY SECURITY OF UKRAINE: THE THREAT OF LONG-TERM ENERGY RESOURCES DEPLETION". Thermophysics and Thermal Power Engineering 42, n.º 3 (6 de agosto de 2020): 5–22. http://dx.doi.org/10.31472/ttpe.3.2020.1.

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In the context of the energy transition, the impact on the energy security of Ukraine of the global threat of depletion of the main types of fossils of traditional energy resources is analyzed. The peculiarities of FER consumption in the recent period in the world as a whole, in the EU and in Ukraine are considered. It points to the fundamental difference in the dynamics of consumption of fossil fuels in the world as a whole and in the EU. The data concerning the proved world reserves of traditional energy resources and terms of their exhaustion are given. Estimates of fossil fuels own stocks in Ukraine are presented and prospects of their use are considered. It is indicated that the development of nuclear energy in Ukraine is promising (as one of the directions of decarbonization of energy in the French interpretation) given the significant world geological reserves of various uranium isotopes. At the same time, it is noted that hybrid technologies of nuclear power deserve special attention.
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28

Kim, Jun Soo y Igal Szleifer. "Depletion Effect on Polymers Induced by Small Depleting Spheres". Journal of Physical Chemistry C 114, n.º 48 (12 de octubre de 2010): 20864–69. http://dx.doi.org/10.1021/jp107598m.

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29

Thivel, David, Graham Finlayson, Maud Miguet, Bruno Pereira, Martine Duclos, Yves Boirie, Eric Doucet, John E. Blundell y Lore Metz. "Energy depletion by 24-h fast leads to compensatory appetite responses compared with matched energy depletion by exercise in healthy young males". British Journal of Nutrition 120, n.º 5 (30 de julio de 2018): 583–92. http://dx.doi.org/10.1017/s0007114518001873.

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AbstractAlthough there is a growing interest for the effects of intermittent fasting on energy balance, this study aimed to compare appetite, energy intake and food reward responses with an energy depletion induced either by 24-h food restriction or an equivalent deficit with exercise in healthy males. In all, twelve healthy lean males (21·5 (sd 0·5) years old; BMI: 22·5 (sd 1·7) kg/m2) participated in this study. Body composition, aerobic capacity, food preferences and energy intake were assessed. They randomly completed three conditions: (i) no depletion (CON); (ii) full 24-h energy restrictions (Def-EI); and (iii) exercise condition (Def-EX). Ad libitum energy intake and food reward were assessed at the end of each session. Appetite feelings were assessed regularly. Ad libitum energy intake was higher on Def-EI (7330 (sd 2975) kJ (1752 (sd 711) kcal) compared with that on CON (5301 (sd 1205) kJ (1267 (sd 288) kcal)) (P<0·05), with no difference between CON and Def-EX (6238 (sd 1741) kJ (1491 (sd 416) kcal) (P=0·38) and between Def-EX and Def-EI (P=0·22). There was no difference in the percent energy ingested from macronutrients. Hunger was lower on CON and Def-EX compared with Def-EI (P<0·001). Satiety was higher on CON and Def-EI compared with that on Def-EX (P<0·001). There was a significant interaction condition × time for food choice fat bias (P=0·04), showing a greater preference for high-fat v. low-fat food during Def-EI and Def-EX. Although 24-h fasting leads to increased energy intake at the following test meal (without total daily energy intake difference), increased hunger profile and decreased post-meal food choice fat bias, such nutritional responses are not observed after a similar deficit induced by exercise.
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30

Muhammad Imran Malik, Shen Ting Zhi y Umar Farooq. "Energy Depletion in MANET While Using AODV Routing Protocol". INTERNATIONAL JOURNAL ON Advances in Information Sciences and Service Sciences 4, n.º 7 (30 de abril de 2012): 272–80. http://dx.doi.org/10.4156/aiss.vol4.issue7.32.

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31

Tinguely, Patrick, Shiko M. Ben-Menahem, Fang He y Georg von Krogh. "Creativity under Time Pressure? When Resources Buffer Energy Depletion". Academy of Management Proceedings 2019, n.º 1 (1 de agosto de 2019): 12595. http://dx.doi.org/10.5465/ambpp.2019.12595abstract.

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32

Desnitsky, V. A. y I. V. Kotenko. "Analysis of energy resource depletion attacks on wireless devices". Izvestiâ vysših učebnyh zavedenij. Priborostroenie 61, n.º 4 (10 de abril de 2018): 291–97. http://dx.doi.org/10.17586/0021-3454-2018-61-4-291-297.

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33

Kalinchuk, Anna V., Anna-Sofia Urrila, Lauri Alanko, Silja Heiskanen, Henna-Kaisa Wigren, Maricel Suomela, Dag Stenberg y Tarja Porkka-Heiskanen. "Local energy depletion in the basal forebrain increases sleep". European Journal of Neuroscience 17, n.º 4 (febrero de 2003): 863–69. http://dx.doi.org/10.1046/j.1460-9568.2003.02532.x.

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34

Bandura, Albert. "Failures in Self-Regulation: Energy Depletion or Selective Disengagement?" Psychological Inquiry 7, n.º 1 (enero de 1996): 20–24. http://dx.doi.org/10.1207/s15327965pli0701_3.

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35

Bhuiyan, Miraj Ahmed, Khalid Zaman, Alaa Mohamd Shoukry, Showkat Gani, Mohamed A. Sharkawy, Sasmoko, Aqeel Khan, Adnan Ahmad y Sanil S. Hishan. "Energy, tourism, finance, and resource depletion: panel data analysis". Energy Sources, Part B: Economics, Planning, and Policy 13, n.º 11-12 (2 de diciembre de 2018): 463–74. http://dx.doi.org/10.1080/15567249.2019.1572837.

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36

Li, Q., C. M. Hohl, R. A. Altschuld y B. T. Stokes. "Energy depletion-repletion and calcium transients in single cardiomyocytes". American Journal of Physiology-Cell Physiology 257, n.º 3 (1 de septiembre de 1989): C427—C434. http://dx.doi.org/10.1152/ajpcell.1989.257.3.c427.

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Rapid fluctuations of intracellular free calcium in single adult rat heart myocytes were monitored by time-resolved fura-2 fluorescence microscopy. Under controlled aerobic conditions (35 degrees C, pH 7.3), electrical stimulation at 0.5 Hz produced a concave negative staircase of calcium transients. When the myocytes were challenged with 3 mM amobarbital (Amytal) and 2 microM carbonyl cyanide m-chlorophenylhydrazone (CCCP) to deplete ATP, the cells became unresponsive to electrical stimulation within 1 min but responded to 10 mM caffeine with a large increase in free calcium. After the development of rigor contracture, the cellular response to caffeine was blunted. Free calcium increased at a variable rate in individual cells, reaching values of 300-1,000 nM after 15 min. When the inhibitors were removed, calcium declined toward control values, and spontaneous contractile activity and calcium transients were invariably observed. During subsequent electrical stimulation, there was a decrease in the half-widths of the calcium transients and an attenuation of the negative staircase. Parallel experiments with cells in suspension indicated that Amytal and CCCP caused ATP to fall from 27.6 +/- 1.6 to 0.7 +/- 0.2 nmol/mg protein, and the percent rod-shaped cells to fall from 70 to 0% in 5 min. Removal of the inhibitors after 15 min caused a rebound in ATP to 5.3 +/- 1.5 nmol/mg within 2 min and 6.6 +/- 1.3 nmol/mg after 10 min.
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37

Lear, M. "The New Zealand Energy Scene Now and Post-Maui". Energy Exploration & Exploitation 13, n.º 2-3 (mayo de 1995): 123–32. http://dx.doi.org/10.1177/0144598795013002-302.

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Supply and demand forecasts to 2020 published by the Ministry of Commerce highlight the significance of the depletion of the Maui gas and condensate field for the New Zealand energy scene. Maui currently produces around 34% of our primary energy and 45% of our transport fuels, including fuel from the synthetic fuels plant. The depletion of Maui around 2010 is expected to reduce our liquid fuel self-sufficiency and reduce the availability of gas for electricity generation and petrochemicals. The Ministry's forecasts conclude this will result in price rises for gas and electricity, and increased use of coal, geothermal, hydro, wind and other renewables for generation. The depletion of the Maui field highlights the importance of developing an attractive petroleum royalty regime to encourage further exploration of New Zealand's petroleum resources.
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38

Lomneth, R. y E. I. Gruenstein. "Energy-dependent cell volume maintenance in UC-11MG human astrocytomas". American Journal of Physiology-Cell Physiology 257, n.º 4 (1 de octubre de 1989): C817—C824. http://dx.doi.org/10.1152/ajpcell.1989.257.4.c817.

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Swelling of astrocytes in the brain is a major cause of the morbidity and mortality associated with stroke and head trauma. Using a human astrocytoma cell line (UC-11MG) as a model system, we studied cell volume changes caused by ATP depletion under conditions mimicking hypoxia. ATP levels were reduced to less than 10% of control using the metabolic inhibitors KCN or antimycin in combination with glucose deprivation. This was sufficient to eliminate ouabain-sensitive 86Rb+ uptake, indicating the Na+-K+-adenosinetriphosphatase was not operating. Furosemide-sensitive 86Rb+ uptake was reduced by approximately 60%, indicating Na+-K+-2Cl- cotransport was also sensitive to ATP loss. ATP depletion resulted in a 30-40% reduction of cell volume within 60 min. ATP depletion also resulted in a net loss of intracellular K+. This loss of K+ could be blocked by Ba2+, indicating the K+ loss was through a conductive channel. When the net K+ loss was blocked by Ba2+, the volume decrease was also prevented. The cells remained viable throughout the time period as judged by exclusion of ethidium bromide by 99% of the cells and recovery of ATP levels to 75% of control within 60 min. We conclude that ATP depletion, following inhibition of glycolysis and oxidative phosphorylation, causes astrocytes to shrink because of a more rapid loss of K+ than uptake of Na+. Thus it appears that ATP depletion alone is not sufficient to account for the rapid phase of astrocytic swelling observed during cerebral ischemia.
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39

Valente, P. C., C. B. da Silva y F. T. Pinho. "The effect of viscoelasticity on the turbulent kinetic energy cascade". Journal of Fluid Mechanics 760 (31 de octubre de 2014): 39–62. http://dx.doi.org/10.1017/jfm.2014.585.

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AbstractDirect numerical simulations of statistically steady homogeneous isotropic turbulence in viscoelastic fluids described by the FENE-P model, such as those laden with polymers, are presented. It is shown that the strong depletion of the turbulence dissipation reported by previous authors does not necessarily imply a depletion of the nonlinear energy cascade. However, for large relaxation times, of the order of the eddy turnover time, the polymers remove more energy from the large scales than they can dissipate and transfer the excess energy back into the turbulent dissipative scales. This is effectively a polymer-induced kinetic energy cascade which competes with the nonlinear energy cascade of the turbulence leading to its depletion. It is also shown that the total energy flux to the small scales from both cascade mechanisms remains approximately the same fraction of the kinetic energy over the turnover time as the nonlinear energy cascade flux in Newtonian turbulence.
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40

Campbell, C. J. "Editorial: The Meaning of Depletion". Energy Exploration & Exploitation 20, n.º 6 (diciembre de 2002): i. http://dx.doi.org/10.1260/014459802321615045.

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41

Rosa, Rui. "Climate Change and Oil Depletion". Energy Exploration & Exploitation 21, n.º 1 (febrero de 2003): 11–28. http://dx.doi.org/10.1260/014459803321615008.

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42

Tritel, Marc y Marilyn D. Resh. "The Late Stage of Human Immunodeficiency Virus Type 1 Assembly Is an Energy-Dependent Process". Journal of Virology 75, n.º 12 (15 de junio de 2001): 5473–81. http://dx.doi.org/10.1128/jvi.75.12.5473-5481.2001.

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ABSTRACT Several recent studies have indicated the involvement of host cell factors in human immunodeficiency virus type 1 (HIV-1) assembly. To ascertain whether ATP-dependent factors play a role in this process, we quantified virus-like particle (VLP) production by ATP-depleted cells. Pharmacological ATP depletion abrogated VLP production without affecting cell viability or inducing degradation of HIV-1 Gag protein. This effect occurred even when the ATP-depleting agents were added 1 h into the assembly process, and it was reversed by removal of these agents. ATP depletion did not affect Gag membrane binding or multimerization. Density gradient analysis indicated that HIV-1 assembly intermediates were stalled late in the assembly process. This conclusion was further supported by electron microscopy analysis, which revealed a preponderance of plasma membrane-associated stalk-like structures in the ATP-depleted cells. Since no HIV-1 proteins bind or hydrolyze ATP, these findings indicate that an ATP-requiring cellular factor is an obligatory participant late in the HIV-1 assembly process.
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43

Borjigin, Burensain. "Resource Depletion in China and its Implications for Mongolia". Inner Asia 16, n.º 2 (10 de diciembre de 2014): 357–76. http://dx.doi.org/10.1163/22105018-12340023.

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China’s natural resources are concentrated in areas inhabited by ethnic minorities which constitute over 60 per cent of China’s territory. When world attention is drawn to China’s rapid economic development and its global energy strategy, people tend to forget how natural resources in the minority regions were extracted to fuel China’s development prior to its high growth era. In other words, who or what regions sustained China’s economy by providing energy and resources after the 1950s? We may also ask what has happened to these minority regions in China’s new energy strategy. Since these regions are frontier regions, what does China’s energy globalisation look like there? This paper studies the historical process of resource extraction in areas inhabited by the Mongols, focusing on the Daqing Oil Field and North China Oil Field. Through discussing how the depletion of oil in these traditional energy bases has led to China’s energy expansion into its northern neighbour of Mongolia, it aims to define the place and significance of Mongolia in China’s global energy strategy.
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44

Seo-Mayer, Patricia W., Gunilla Thulin, Li Zhang, Daiane S. Alves, Thomas Ardito, Michael Kashgarian y Michael J. Caplan. "Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia". American Journal of Physiology-Renal Physiology 301, n.º 6 (diciembre de 2011): F1346—F1357. http://dx.doi.org/10.1152/ajprenal.00420.2010.

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Alterations in epithelial cell polarity and in the subcellular distributions of epithelial ion transport proteins are key molecular consequences of acute kidney injury and intracellular energy depletion. AMP-activated protein kinase (AMPK), a cellular energy sensor, is rapidly activated in response to renal ischemia, and we demonstrate that its activity is upregulated by energy depletion in Madin-Darby canine kidney (MDCK) cells. We hypothesized that AMPK activity may influence the maintenance or recovery of epithelial cell organization in mammalian renal epithelial cells subjected to energy depletion. MDCK cells were ATP depleted through a 1-h incubation with antimycin A and 2-deoxyglucose. Immunofluoresence localization demonstrated that this regimen induces mislocalization of the Na-K-ATPase from its normal residence at the basolateral plasma membrane to intracellular vesicular compartments. When cells were pretreated with the AMPK activator metformin before energy depletion, basolateral localization of Na-K-ATPase was preserved. In MDCK cells in which AMPK expression was stably knocked down with short hairpin RNA, preactivation of AMPK with metformin did not prevent Na-K-ATPase redistribution in response to energy depletion. In vivo studies demonstrate that metformin activated renal AMPK and that treatment with metformin before renal ischemia preserved cellular integrity, preserved Na-K-ATPase localization, and led to reduced levels of neutrophil gelatinase-associated lipocalin, a biomarker of tubular injury. Thus AMPK may play a role in preserving the functional integrity of epithelial plasma membrane domains in the face of energy depletion. Furthermore, pretreatment with an AMPK activator before ischemia may attenuate the severity of renal tubular injury in the context of acute kidney injury.
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45

Alyaseri, Ahmed Jassim. "THE REALITY AND FUTURE OF RENEWABLE ENERGY SOURCES IN THE GLOBAL ENERGY MARKET". Akkad Journal Of Multidisciplinary Studies 1, n.º 4 (25 de junio de 2022): 270–83. http://dx.doi.org/10.55202/ajms.v1i4.98.

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For a long time, traditional energy sources have been spreading a great deal of safety in meeting global energy needs, but with the natural depletion of their reserves and their continued increasing consumption as global populations and many changing factors increase, uncertainty has begun to revolve around the adequacy of these sources to meet the world's current and future energy needs. In addition to the concern for environmental pollution in general, the depletion of traditional energy sources and their effects on the environment has necessitated the search for other energy sources to ensure the supply and its continuation. Therefore renewable energy sources have emerged as inexhaustible and highly available sources on the planet, and the energy generated from them is clean. Furthermore, the significant developments brought about by technology in oil and natural gas extraction techniques from non-traditional sources and the light of their vast reserves of discovered Technically, recoverable sources have led to the export of these sources with renewable sources in the global energy supply mix to take an active role in the structure of the worldwide energy balance.
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46

Gourlay, T., J. Fleming y KM Taylor. "The effects of pulsatile flow on the leukocyte depleti ng qualities of the Pall LG6 leukocyte depleting arterial line filter: a laboratory investigation". Perfusion 7, n.º 3 (julio de 1992): 227–32. http://dx.doi.org/10.1177/026765919200700308.

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The Pall LG6 arterial line filter has, in a previous publication, demonstrated its inherent leukocyte depleting qualities. This initial study was however carried out under continuous flow conditions. The present study was designed to assess the effectiveness of the LG6 filter in performing this leukocyte removal function under the more dynamic conditions of pulsatile flow. In addition to leukocyte depletion, the general blood handling and degree of energy absorbtion associated with the LG6 and Stat-Prime filters was also assessed. The results demonstrated that the LG6 filter was unaffected by the flow regime employed in terms of leukocyte removal and platelet depletion. There was a higher level of measured haemolysis associated with the use of pulsatile rather than nonpulsatile flow, however, this was the case with both filter types and was not found to be the case when generated values were computed. The LG6 filter absorbed more energy than the Stat-Prime filter as reflected by energy equivalent pressure (EEP) measurement, but this difference did not reach a level which was considered to be clinically significant.
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47

Chen, Jing y Mark C. Wagner. "Altered membrane-cytoskeleton linkage and membrane blebbing in energy-depleted renal proximal tubular cells". American Journal of Physiology-Renal Physiology 280, n.º 4 (1 de abril de 2001): F619—F627. http://dx.doi.org/10.1152/ajprenal.2001.280.4.f619.

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The effects of energy depletion on two membrane-cytoskeletal linker proteins (ezrin and myosin-1β) and membrane bleb formation were studied in isolated rabbit proximal tubule cells. Measurements of cytoskeletal-membrane interactions by using the laser optic trap method revealed a stronger association of control tubule membrane with the apical cytoskeleton compared with the basal cytoskeleton. Energy depletion weakened the apical membrane-cytoskeleton interactions to a greater degree. Biochemical studies demonstrated that energy depletion altered both ezrin and myosin-1β. The salt-insensitive ezrin fraction dissociated from the cytoskeleton; myosin-1β redistributed from the peripheral cytoskeleton to a perinuclear/nuclear complex. These changes in ezrin and myosin-1β and the weakening of the membrane-cytoskeleton interactions correlated with the release of brush-border membrane blebs observed by differential interference contrast microscopy. Permeability of membrane blebs was also evaluated during energy depletion and indicated an increased permeabilization of basal blebs to 3-kDa dextrans. These results support the hypothesis that alterations in membrane-cytoskeleton linkers facilitate the formation and detachment of blebs by weakening membrane-cytoskeleton interactions.
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48

Abbatt, J. P. D. y M. J. Molina. "Status of Stratospheric Ozone Depletion". Annual Review of Energy and the Environment 18, n.º 1 (noviembre de 1993): 1–29. http://dx.doi.org/10.1146/annurev.eg.18.110193.000245.

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49

Jemaà, Mohamed, Myriam Fezai y Florian Lang. "Inhibition of Suicidal Erythrocyte Death by Reversine". Cellular Physiology and Biochemistry 41, n.º 6 (2017): 2363–73. http://dx.doi.org/10.1159/000475654.

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Background/Aims: The A3 adenosine receptor antagonist reversine (2-(4-morpholinoanilino)-6-cyclohexylaminopurine) influences cellular differentiation, inhibits cell proliferation, induces cell-cycle arrest, triggers apoptosis, causes cell swelling with polyploidy and stimulates autophagy. The effect on apoptosis involves mitochondria and caspases. Erythrocytes are lacking mitochondria but express caspases and are, similar to apoptosis of nucleated cells, able to enter suicidal erythrocyte death or eryptosis. Stimulators of eryptosis include increase of cytosolic Ca2+ activity ([Ca2+]i), energy depletion and oxidative stress. The present study explored, whether reversine influences eryptosis. Methods: Flow cytometry was employed to quantify phosphatidylserine exposure at the cell surface from annexin-V-binding and cell volume from forward scatter. Measurements were made without or with energy depletion (glucose deprivation for 48 hours), Ca2+ loading (30 minutes treatment with 1 µM Ca2+ ionophore ionomycin), or oxidative stress (15 min exposure to 0.3 mM tert-butylhydroperoxide). Results: A 48 hours exposure of human erythrocytes to reversine (1-10 µM) did not significantly modify the percentage of annexin-V-binding cells and forward scatter. Energy depletion, Ca2+ loading, and oxidative stress were each followed by profound and significant increase of the percentage annexin-V-binding erythrocytes and a significant decrease of forward scatter. The effects of each, Ca2+ loading, energy depletion and oxidative stress on annexin-V-binding were significantly blunted in the presence of reversine (1-10 µM). The effect of ionomycin, but not the effects of energy depletion and oxidative stress on forward scatter were again significantly blunted in the presence of reversine (≥1 µM]. Conclusions: Reversine is a powerful inhibitor of cell membrane scrambling following energy depletion, Ca2+ loading and oxidative stress.
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50

Chopra, Atul R., Ramakrishna Kommagani, Pradip Saha, Jean-Francois Louet, Christina Salazar, Junghun Song, Jaewook Jeong et al. "Cellular Energy Depletion Resets Whole-Body Energy by Promoting Coactivator-Mediated Dietary Fuel Absorption". Cell Metabolism 13, n.º 1 (enero de 2011): 35–43. http://dx.doi.org/10.1016/j.cmet.2010.12.001.

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