Literatura académica sobre el tema "DNA MTase"
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Artículos de revistas sobre el tema "DNA MTase"
Zhu, Chen, Shuting Zhang, Chengzhe Zhou, Lan Chen, Haifeng Fu, Xiaozhen Li, Yuling Lin, Zhongxiong Lai y Yuqiong Guo. "Genome-wide investigation and transcriptional analysis of cytosine-5 DNA methyltransferase and DNA demethylase gene families in tea plant (Camellia sinensis) under abiotic stress and withering processing". PeerJ 8 (14 de enero de 2020): e8432. http://dx.doi.org/10.7717/peerj.8432.
Texto completoLi, Jiang, Caili Li y Shanfa Lu. "Identification and characterization of the cytosine-5 DNA methyltransferase gene family in Salvia miltiorrhiza". PeerJ 6 (5 de marzo de 2018): e4461. http://dx.doi.org/10.7717/peerj.4461.
Texto completoGinibre, Nadège, Ludovic Legrand, Victoria Bientz, Jean-Claude Ogier, Anne Lanois, Sylvie Pages y Julien Brillard. "Diverse Roles for a Conserved DNA-Methyltransferase in the Entomopathogenic Bacterium Xenorhabdus". International Journal of Molecular Sciences 23, n.º 19 (9 de octubre de 2022): 11981. http://dx.doi.org/10.3390/ijms231911981.
Texto completoWang, Yuehua, Yingli Han, Fangyu Zhou, Tingting Fan y Feng Liu. "Simple Detection of DNA Methyltransferase with an Integrated Padlock Probe". Biosensors 12, n.º 8 (26 de julio de 2022): 569. http://dx.doi.org/10.3390/bios12080569.
Texto completoShi, Lisha, Huimin Shen, Jiawei Liu, Hongmin Hu, Hongyan Tan, Xiulian Yang, Lianggui Wang y Yuanzheng Yue. "Exploration of the Potential Transcriptional Regulatory Mechanisms of DNA Methyltransferases and MBD Genes in Petunia Anther Development and Multi-Stress Responses". Genes 13, n.º 2 (8 de febrero de 2022): 314. http://dx.doi.org/10.3390/genes13020314.
Texto completoBheemanaik, Shivakumara, Yeturu V. R. Reddy y Desirazu N. Rao. "Structure, function and mechanism of exocyclic DNA methyltransferases". Biochemical Journal 399, n.º 2 (27 de septiembre de 2006): 177–90. http://dx.doi.org/10.1042/bj20060854.
Texto completoHiraoka, Satoshi, Tomomi Sumida, Miho Hirai, Atsushi Toyoda, Shinsuke Kawagucci, Taichi Yokokawa y Takuro Nunoura. "Diverse DNA modification in marine prokaryotic and viral communities". Nucleic Acids Research 50, n.º 3 (21 de enero de 2022): 1531–50. http://dx.doi.org/10.1093/nar/gkab1292.
Texto completoZhang, Yufeng, Chunxiao Liu, Xiaoyang Xu, Jialiang Kan, Hui Li, Jing Lin, Zongming Cheng y Youhong Chang. "Comprehensive Analysis of the DNA Methyltransferase Genes and Their Association with Salt Response in Pyrus betulaefolia". Forests 14, n.º 9 (30 de agosto de 2023): 1751. http://dx.doi.org/10.3390/f14091751.
Texto completoOerum, Stephanie, Vincent Meynier, Marjorie Catala y Carine Tisné. "A comprehensive review of m6A/m6Am RNA methyltransferase structures". Nucleic Acids Research 49, n.º 13 (22 de mayo de 2021): 7239–55. http://dx.doi.org/10.1093/nar/gkab378.
Texto completoZhang, Weiting, Xiaolong Zu, Yanling Song, Zhi Zhu y Chaoyong James Yang. "Detection of DNA methyltransferase activity using allosteric molecular beacons". Analyst 141, n.º 2 (2016): 579–84. http://dx.doi.org/10.1039/c5an01763g.
Texto completoTesis sobre el tema "DNA MTase"
Mutamba, James T. (James Tendai). "XRCC1 & DNA MTases : direct and indirect modulation of inflammation-induced DNA damage". Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/67206.
Texto completoCataloged from PDF version of thesis.
Includes bibliographical references (p. 164-183).
Cancer causes 13% of all deaths worldwide. Inflammation-mediated cancer accounts for ~15% of all malignancies, strongly necessitating investigation of the molecular interactions at play. Inflammatory reactive oxygen and nitrogen species (RONs), including peroxynitrite and nitric oxide (NO'), may potentiate malignancy. We hypothesize that the base excision repair (BER) pathway modulates susceptibility to malignancy, by modulating the BER-intermediate levels, large scale genomic rearrangements and toxicity following exposure to RONs. We further hypothesize that DNA methyltransferases are responsible for the memory of genotoxic insult, and the epigenetic propagation of genomic instability, following exposure to genotoxins. Here, we exploited cell lines engineered to carry deficiencies in BER to study repair of DNA damage induced by RONs. Toxicity and BER-intermediate levels were evaluated in XRCC1 proficient and deficient cells, following exposure to the peroxynitrite donor, SIN-1 and to NO*. Using the alkaline comet assay, we find that while XRCC1 proficient and deficient CHO cells incur equivalent levels of SIN-1 induced BER-intermediates, the XRCC1 null cells are more sensitive to killing by SIN-1, as assessed by clonogenic survival. Furthermore, using bioreactors to expose CHO cells to NO', we found that the BER-intermediate levels measured in XRCC1 null cells were lower than in WI cells. We found that while XRCC1 can facilitate AAG-mediated excision of the inflammation-associated base lesions ethenoadenine and hypoxanthine, in vitro; XRCC1 deficient human cells were no more susceptible to NO' than WT cells. However, in live glioblastoma cells, XRCC1 is acting predominantly downstream of AAG glycosylase. This work is some of the first to assess the functional role of XRCC1, in response to RONs and suggests complexities in the role of XRCC1. We also demonstrate that the underlying basis for the memory of a genotoxic insult and the subsequent propagation of genomic instability is dependent on the DNA methyltransferases, Dnmtl and Dnmt3a. We found that a single exposure led to long-term genome destabilizing effects that spread from cell to cell, and therefore provided a molecular mechanism for these persistent bystander effects. Collectively, our findings impact current understanding of cancer risk and suggest mechanisms for suppressing genomic instability, following exposure to inflammatory genotoxins.
by James T. Mutamba.
Ph.D.
Shivakumara, B. "Structure-Function And Mechanistic Studies On KpnI DNA Methyltransferase". Thesis, 2005. http://etd.iisc.ernet.in/handle/2005/1373.
Texto completoKrishnamurthy, Vinita. "Cofactor And DNA Interactions In The EcoPI DNA Methyltransferase". Thesis, 1996. http://etd.iisc.ernet.in/handle/2005/1683.
Texto completoBanerjee, Arun. "Biochemical Characterization Of An Acid-Adaptive Type III DNA Methyltransferase From Helicobacter Pylori 26695 And Its Biological Significance". Thesis, 2011. http://etd.iisc.ernet.in/handle/2005/2420.
Texto completoCapítulos de libros sobre el tema "DNA MTase"
Anastácio, Rita Ferreira, Ana Filipa Martins y Luiz Oosterbeek. "Áreas de Potencial Arqueológico na Região do Médio Tejo: Modelo Espacial Preditivo". En Arqueologia em Portugal 2020 - Estado da Questão - Textos, 203–22. Associação dos Arqueólogos Portugueses e CITCEM, 2020. http://dx.doi.org/10.21747/978-989-8970-25-1/arqa15.
Texto completoActas de conferencias sobre el tema "DNA MTase"
Poruchynsky, Marianne S., Edina Komlodi-Pasztor, Julia Wilkerson, Shana Trostel, Mauricio Burroto-Pichun y Tito Fojo. "Abstract LB-106: Microtubule-targeting agents (MTAs) disrupt intracellular trafficking of DNA repair proteins and augment the toxicity of DNA damaging agents (DDAs)". En Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-lb-106.
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