Bibliografías temáticas / DMEK

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Literatura académica sobre el tema "DMEK"

Autor: Grafiati
Publicado: 10 de marzo de 2023
Última modificación: 16 de junio de 2025

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Artículos de revistas sobre el tema "DMEK"

1

Oganesyan, Oganes G., A. A. Grdikanyan, S. S. Yakovleva, and V. R. Getadaryan. "THE PARTIAL DESCEMET'S STRIPPING WITH TRANSPLANTATION OF DESCEMET'S TRANSPLANT UNDER ENDOTHELIAL DYSTROPHY OF CORNEA." Medical Journal of the Russian Federation 23, no. 5 (2017): 248–53. http://dx.doi.org/10.18821/0869-2106-2017-23-5-248-253.

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The DMEK technique is applied five times more rarely than DS(A)EK despite that DMEK provides higher functional result. The main causes are technical "convolution" of implementation, long period of training, accompanied by prolonged operations, higher reject control of donor's tissue, increased rate of dependency of endothelium and mismatch of transplant. Therefore, an efficient technique is needed similar to DMEK though simpler than DMEK.The purpose of study. To analyze the results of implantation of Descemet's transplant (DMET) in patients with endothelium dystrophy of cornea (Fuchs) on the basis of limited clinical observations.Material of study. In two years, DMET was implemented to 12 patients. The study included 6 patients with average age of 60±18 years (from 29 to 80 years). All female patients had primary endothelial dystrophy and one male patient had secondary endothelial dystrophy. The visual acuity prior to DMET in average made up to 0,2±0,2 (from 0,01 to 0,5). The average CTR according optical coherent eye tomography made up to 685±53 µm (from 622 to 749 µm). Results. Within available periods of observation, resorption of edema of cornea takes place in 4 patients (67%) and visual acuity increased from average 0,2±0,1 to 0,45±0,3. In various periods density of endothelium cells varied from 549 to 689 kl per mm2. The indices of optical coherent eye tomography decreased from pre-operational 685±53 µm to 553±15 µm. Conclusion. The results testify efficiency of DMET. The period of restoration of transparency of cornea can vary from 1 to 6 months. The indices of density of endothelium cells are inferior to indices after DMEK. Also, DMET is ineffective in case of secondary dystrophy and at most efficient on previously non-operated eyes.
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2

Giebel, Arthur W. "DMEK." International Ophthalmology Clinics 53, no. 1 (2013): 1–14. http://dx.doi.org/10.1097/iio.0b013e31827744c4.

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3

Morelli, Alberto, Rosangela Ferrandina, Eleonora Favuzza, Michela Cennamo, and Rita Mencucci. "3D Visualization System in Descemet Membrane Endothelial Keratoplasty (DMEK): A Six-Month Comparison with Conventional Microscope." Journal of Clinical Medicine 11, no. 15 (2022): 4312. http://dx.doi.org/10.3390/jcm11154312.

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Background: To compare the efficacy and safety of Descemet membrane endothelial keratoplasty (DMEK) surgery using the three-dimensional (3D) display system NGENUITY to DMEK surgery performed with the traditional microscope (TM) in patients affected by Fuchs Endothelial Corneal Disease (FECD). Methods: Retrospective comparative study of 40 pseudophakic eyes of 40 patients affected by FECD who underwent DMEK surgery. Twenty patients (3D group) were operated on using the 3D display system and 20 patients (TM group) were operated on using the traditional microscope. Best spectacle corrected visual acuity (BSCVA), central corneal thickness (CCT), endothelial cell density (ECD) and corneal densitometry (CD) values were documented before and at 1, 3 and 6 months after DMEK. Intra- and postoperative complications were recorded. Results: The baseline assessments did not differ between the two groups (p > 0.05). Global surgical time and time to perform descemetorhexis were significantly lower in the TM group (p = 0.04 and p = 0.02, respectively). BSCVA, CCT, ECD and CD values did not differ significantly in the two groups at all follow-ups (p > 0.05). Complication rate was similar between the two groups. Conclusion: Three-dimensional display systems can be securely employed in DMEK surgery considering the satisfactory clinical outcomes, including Scheimpflug CD. Nevertheless, the slightly longer surgical time of the 3D DMEKs may lead to surgeons’ hesitancy. The main advantages of the heads-up approach may be the improved ergonomic comfort during surgery and the utility of assistants in surgical training.
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4

Perez, AlfonsoVasquez, Mehran Zarei-Ghanavati, and Christopher Liu. "DMEK calling." Journal of Ophthalmic and Vision Research 11, no. 4 (2016): 343. http://dx.doi.org/10.4103/2008-322x.194067.

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5

Gorovoy, Mark S. "DMEK Complications." Cornea 33, no. 1 (2014): 101–4. http://dx.doi.org/10.1097/ico.0000000000000023.

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6

Semler-Collery, Axelle, Florian Bloch, George Hayek, Christophe Goetz, and Jean Marc Perone. "Comparison of triple-DMEK to pseudophakic-DMEK: A cohort study of 95 eyes." PLOS ONE 17, no. 5 (2022): e0267940. http://dx.doi.org/10.1371/journal.pone.0267940.

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Previous comparative studies show that triple Descemet membrane endothelial keratoplasty (DMEK) (i.e. phacoemulsification followed immediately by DMEK) has either equivalent or better visual outcomes than DMEK in pseudophakic patients. To resolve this discrepancy, a retrospective cohort study was conducted. All consecutive patients with Fuchs Endothelial Corneal Dystrophy who underwent triple or pseudophakic DMEK in 2015–2019 in a tertiary-care hospital (France) and were followed for >12 months were compared in terms of best spectacle-corrected visual acuity (BSCVA), final refractive outcomes, and endothelial-cell loss at 12 months as well as rebubbling rates. The triple-DMEK (40 eyes, 34 patients) and pseudophakic-DMEK (55 eyes, 43 patients) groups were similar in terms of age and other baseline variables. They also did not differ in final BSCVA (both 0.03 logMAR), final endothelial-cell loss (54% vs. 48%), or astigmatism (-1.25 vs. -1 D). At 12 months, triple-DMEK associated with significantly smaller residual hyperopia (0.75 vs. 1 D; p = 0.04) and spherical equivalence (0 vs. 0.5 D; p = 0.02). Triple-DMEK also tended to associate with more frequent rebubbling (40% vs. 24%, p = 0.09). In conclusion, while triple-DMEK and pseudophakic-DMEK achieved similar visual acuity improvement, triple-DMEK was superior in terms of final sphere and spherical refraction but also tended to have higher complication rates.
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7

Oganesyan, Oganes G., P. V. Makarov, A. A. Grdikanyan, V. R. Getadaryan, and S. V. Milash. "THE PARTIAL TRANSPLANTATION OF DESCEMET’S MEMBRANE WITH ENDOTHELIUM (½ AND ¼ DMEK)." Medical Journal of the Russian Federation 24, no. 2 (2018): 78–82. http://dx.doi.org/10.18821/0869-2106-2018-24-2-78-82.

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The lamellar keratoplasty is the first operation of choice under selective pathology of cornea. In view of satisfactory results of endothelium surgery similar operations are implemented at more earlier stages that increases need in donor tissue. The life-span of population increases hence number of patients in need of cornea transplantation also increases and number of intact cadaver corneas decreases because of stable increasing of number of surgical interventions at the frontal section of eye. The purpose of study is to analyze operations of partial transplantation of Descemet's membrane with endothelium (½ DMEK and ¼ DMEK). Material and methods. The analysis was applied to the results of 10 operations ½ DMEK (semi-DMEK, hemi-DMEK) and 10 operations ¼ DMEK, implemented at eyes of 20 patients with primary endothelium dystrophy. The average age of patients made up to 64,9±10,4 years. The average visual acuity prior to implementation of partial DMEK amounted to 0,14 ± 0,08, average central thickness of cornea, according data of optical coherent tomography, made up to 669 ± 91 мкм. Results. In 16 out of 20 cases of partial DMEK, restoration of transparency of cornea, resorption of edema and increasing of visual acuity was achieved. In other 4 cases, during one week after partial DMEK, a subtotal DMEK was implemented. In 16 cases, average visual acuity increased up to 0,8 ± 0,3 three months later after operation. Conclusion. The techniques of partial transplantation of Descemet's membrane with endothelium (¼ DMEK и ½ DMEK) are efficient for treatment of primary endothelium pathology of cornea and permit to apply donor's material as much as possible rationally.
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8

Lohmann, Tibor, Sabine Baumgarten, Niklas Plange, Peter Walter, and Matthias Fuest. "Effects of uncomplicated Descemet membrane endothelial keratoplasty on the central retinal thickness." Graefe's Archive for Clinical and Experimental Ophthalmology 259, no. 9 (2021): 2731–41. http://dx.doi.org/10.1007/s00417-021-05203-2.

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Abstract Purpose To determine retinal thickness (RT) changes and the incidence of macular edema after uncomplicated Descemet membrane endothelial keratoplasty (DMEK-ME) in patients without ME risk factors. Methods In this retrospective study, 107 pseudophakic eyes of 74 patients with Fuchs endothelial dystrophy (FED) (79.4%) or bullous keratopathy (BK) (20.6%) underwent DMEK surgery between 2016 and 2019 at the Department of Ophthalmology, RWTH Aachen University. Patients with intra- or postoperative complications as well as pre-existing risk factors for ME were excluded. Macular spectral-domain optical coherence tomography (SD-OCT) and best spectacle-corrected visual acuity (BSCVA) measurements were performed before, 1 week, 1 month, and 6 months after surgery. Retinal thickness (RT) was analyzed in the central foveal 1 mm (CSF), parafoveal 3 mm and 6 mm subfield. Results Eight eyes (7.5%) developed DMEK-ME 1 month after surgery. Six DMEK-ME eyes (75%) were rebubbled, compared with 31.3% (31 of 99; P = 0.02) of the non DMEK-ME eyes. DMEK-ME eyes had a significantly thicker CSF 1 month after surgery (432.0 ± 97.6 μm) compared with non-DMEK-ME eyes (283.7 ± 22.2 μm; P = 0.01). The other subfields and time points showed no significant RT changes. DMEK-ME significantly impaired BSCVA (0.38 ± 0.92 logMAR) only 1 month after surgery in comparison to the non DMEK-ME eyes (0.23 ± 0.87 logMAR, P = 0.015). Conclusion Excluding systemic and surgery-related risk factors, rebubbling increases the risk of DMEK-ME. Performing a CSF scan 1 month after surgery, particularly in rebubbled eyes, efficiently detects DMEK-ME and allows the prompt initiation of treatment, e.g., topical corticosteroid and non-steroidal (NSAID) eye drops.
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9

Romano, Vito, Luca Pagano, Kunal A. Gadhvi, et al. "Clinical outcomes of pre-loaded ultra-thin DSAEK and pre-loaded DMEK." BMJ Open Ophthalmology 5, no. 1 (2020): e000546. http://dx.doi.org/10.1136/bmjophth-2020-000546.

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ObjectiveTo compare clinical outcomes and complications between pre-loaded ultra-thin Descemet stripping automated endothelialkeratoplasty (pl-UT-DSAEK) and pre-loaded Descemet membrane endothelial keratoplasty (pl-DMEK).Methods and analysisComparative study in patients with endothelial dysfunction associated with Fuchs endothelial corneal dystrophy and pseudophakic bullous keratopathy who underwent pl-UT-DSAEK or pl-DMEK transplants. For both groups, the tissues were pre-loaded at the Fondazione Banca degli Occhi del Veneto (Venice, Italy) and shipped to The Royal Liverpool University Hospital (Liverpool, UK). Best corrected visual acuity (BCVA) and re-bubbling rates were the main outcome measures.Results56 eyes of 56 patients were included. 31 received pl-UT-DSAEK and 25 received pl-DMEK. At 12 months, BCVA (LogMAR) was significantly better for pl-DMEK (0.17±0.20 LogMAR) compared with pl-UT-DSAEK (0.37±0.37 LogMAR, p<0.01). The percentage of people that achieved ≥20/30 was significantly higher in the pl-DMEK group. The rate of re-bubbling, however, was significantly higher for pl-DMEK (44.0%) than for Pl-UT-DSAEK (12.9%), p<0.01.ConclusionPl-DMEK offers better BCVA than pl-UT-DSAEK. The higher re-bubbling rate associated with pre-loaded DMEK is of concern.
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10

Terry, Mark A., Michael D. Straiko, Peter B. Veldman, et al. "Standardized DMEK Technique." Cornea 34, no. 8 (2015): 845–52. http://dx.doi.org/10.1097/ico.0000000000000479.

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