Literatura académica sobre el tema "CRISPR spacers"
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Artículos de revistas sobre el tema "CRISPR spacers"
Horvath, Philippe, Dennis A. Romero, Anne-Claire Coûté-Monvoisin, Melissa Richards, Hélène Deveau, Sylvain Moineau, Patrick Boyaval, Christophe Fremaux y Rodolphe Barrangou. "Diversity, Activity, and Evolution of CRISPR Loci in Streptococcus thermophilus". Journal of Bacteriology 190, n.º 4 (7 de diciembre de 2007): 1401–12. http://dx.doi.org/10.1128/jb.01415-07.
Texto completoToro, Magaly, Guojie Cao, Wenting Ju, Marc Allard, Rodolphe Barrangou, Shaohua Zhao, Eric Brown y Jianghong Meng. "Association of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Elements with Specific Serotypes and Virulence Potential of Shiga Toxin-Producing Escherichia coli". Applied and Environmental Microbiology 80, n.º 4 (13 de diciembre de 2013): 1411–20. http://dx.doi.org/10.1128/aem.03018-13.
Texto completoAchigar, Rodrigo, Martina Scarrone, Geneviève M. Rousseau, Cécile Philippe, Felipe Machado, Valentina Duvós, María Pía Campot et al. "Ectopic Spacer Acquisition in Streptococcus thermophilus CRISPR3 Array". Microorganisms 9, n.º 3 (1 de marzo de 2021): 512. http://dx.doi.org/10.3390/microorganisms9030512.
Texto completovan der Ploeg, Jan R. "Analysis of CRISPR in Streptococcus mutans suggests frequent occurrence of acquired immunity against infection by M102-like bacteriophages". Microbiology 155, n.º 6 (1 de junio de 2009): 1966–76. http://dx.doi.org/10.1099/mic.0.027508-0.
Texto completoSerbanescu, M. A., M. Cordova, K. Krastel, R. Flick, N. Beloglazova, A. Latos, A. F. Yakunin, D. B. Senadheera y D. G. Cvitkovitch. "Role of the Streptococcus mutans CRISPR-Cas Systems in Immunity and Cell Physiology". Journal of Bacteriology 197, n.º 4 (8 de diciembre de 2014): 749–61. http://dx.doi.org/10.1128/jb.02333-14.
Texto completoPavlova, Yekaterina S., David Paez-Espino, Andrew Yu Morozov y Ilya S. Belalov. "Searching for fat tails in CRISPR-Cas systems: Data analysis and mathematical modeling". PLOS Computational Biology 17, n.º 3 (26 de marzo de 2021): e1008841. http://dx.doi.org/10.1371/journal.pcbi.1008841.
Texto completoDeveau, Hélène, Rodolphe Barrangou, Josiane E. Garneau, Jessica Labonté, Christophe Fremaux, Patrick Boyaval, Dennis A. Romero, Philippe Horvath y Sylvain Moineau. "Phage Response to CRISPR-Encoded Resistance in Streptococcus thermophilus". Journal of Bacteriology 190, n.º 4 (7 de diciembre de 2007): 1390–400. http://dx.doi.org/10.1128/jb.01412-07.
Texto completoBolotin, Alexander, Benoit Quinquis, Alexei Sorokin y S. Dusko Ehrlich. "Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin". Microbiology 151, n.º 8 (1 de agosto de 2005): 2551–61. http://dx.doi.org/10.1099/mic.0.28048-0.
Texto completoHeussler, Gary E., Jon L. Miller, Courtney E. Price, Alan J. Collins y George A. O'Toole. "Requirements for Pseudomonas aeruginosa Type I-F CRISPR-Cas Adaptation Determined Using a Biofilm Enrichment Assay". Journal of Bacteriology 198, n.º 22 (29 de agosto de 2016): 3080–90. http://dx.doi.org/10.1128/jb.00458-16.
Texto completoLopatina, Anna, Sofia Medvedeva, Daria Artamonova, Matvey Kolesnik, Vasily Sitnik, Yaroslav Ispolatov y Konstantin Severinov. "Natural diversity of CRISPR spacers of Thermus : evidence of local spacer acquisition and global spacer exchange". Philosophical Transactions of the Royal Society B: Biological Sciences 374, n.º 1772 (25 de marzo de 2019): 20180092. http://dx.doi.org/10.1098/rstb.2018.0092.
Texto completoTesis sobre el tema "CRISPR spacers"
Medvedeva, Sofia. "Natural Diversity of CRISPR Spacers". Electronic Thesis or Diss., Sorbonne université, 2019. http://www.theses.fr/2019SORUS538.
Texto completoCRISPR-Cas is a prokaryotic immunity system against mobile genetic elements, such as viruses and plasmids. The system consists of two components: the clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas). In the CRISPR array, short fragments of foreign DNA, called spacers, are interleaved with palindromic repeats. During the adaptation stage of the CRISPR-Cas immunity, new spacers are inserted into the CRISPR array, whereas during the expression and interference stages, spacers are transcribed, processed and complexed with Cas proteins to target the complementary foreign DNA or RNA molecules for degradation. Analysis of CRISPR spacers is a valuable source of information about virus-host interactions, particularly powerful when applied to metagenomic data. In this work, we explored the diversity of CRISPR spacers in different natural prokaryotic communities, including extinct Escherichia coli community from a mammoth intestine, Flavobacterium communities from Antarctic surface snow, Thermus communities from four distant hot springs in Italy and Chile, and Sulfolobales community from a Japanese thermal field. The comparison of obtained environmental spacer sets with each other and with spacers from public databases as well as with sequences of viruses allowed us to reach several non-trivial conclusions and to gain insights into virus-host and virus-virus interactions in natural microbial communities
Vyhovskyi, Danylo. "In vivo studies of CRISPR adaptation mechanism and specificity". Electronic Thesis or Diss., Sorbonne université, 2023. http://www.theses.fr/2023SORUS729.
Texto completoThis thesis investigates the mechanisms of the CRISPR-Cas adaptive immunity in prokaryotes, primarily using the type I-E system in Escherichia coli, focusing on the spacer acquisition process and the system's specificity. It sheds light on the dynamics of spacers generation and integration into CRISPR arrays, comparing naive and primed adaptation modes. The study reveals that a particular PAM (protospacer adjacent motif) - proximal sequence impedes spacer acquisition in the primed mode, providing a distinct identifier for naturally acquired spacers. The study further reveals the role of non-Cas enzymes, linked to DNA repair pathways, in spacer generation and processing, contributing to CRISPR adaptation and interference.Another course of the study identifies potential hazards posed by off-target effects caused by Cas9 (dCas9) RNA-guided enzyme that can inadvertently silence genes. This occurs when there's a minimal match of just four nucleotides between the gRNA and the target within the PAM-proximal sequence, emphasizing the need for careful experimental design in CRISPR-Cas research.Overall, the thesis expands understanding of the complex molecular mechanisms behind CRISPR adaptation, highlighting the role of non-Cas proteins and the significance of a specific genetic context of seed sequences, leading to the development of more precise and efficient genetic engineering tools
Jacot-Guillarmod, Paul. "Sobriety of crisp and fuzzy topological spaces". Thesis, Rhodes University, 2004. http://hdl.handle.net/10962/d1005228.
Texto completoStens, Cassandra, Isabella Enoksson y Sara Berggren. "The CRISPR-Cas system". Thesis, Linköpings universitet, Institutionen för fysik, kemi och biologi, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-171997.
Texto completoWong, Shi Pey. "Analysis of the adaptation mechanism in the type II-A CRISPR-Cas system". Doctoral thesis, Humboldt-Universität zu Berlin, 2019. http://dx.doi.org/10.18452/19806.
Texto completoThe RNA guided adaptive immune system CRISPR (clustered regularly interspaced short palindromic repeats) Cas (CRISPR-associated) immunizes prokaryotic cells against mobile genetic elements (MGEs). During spacer acquisition stage, a short nucleic acid sequence (prespacer) is acquired from the MGEs, processed and finally integrated into the CRISPR array as a spacer, which serves as genetic memory to defend against the invasion of the cognate MGEs. The molecular mechanism for the spacer acquisition of the type II A systems, which encode cas9, cas1, cas2, csn2 and tracrRNA, is still not fully understood. Therefore, we investigated the requirement of the different Cas proteins for spacer acquisition. We verified the acquisition activity of the type II A systems of Streptococcus thermophilus LMD 9 via spacer acquisition studies by phage challenge. We observed higher acquisition rates in the CRISPR3 locus compared to the CRISPR1 locus. Our plasmid-based spacer acquisition study confirmed in addition to Cas1, Cas2 and Csn2 the requirement of Cas9 for spacer acquisition. Yeast two hybrid and pull down approaches revealed specific interactions among the Cas proteins, as well as interactions between Cas and DNA repair proteins. The interaction regions of Cas1 with Cas9 were identified by SPOT peptide assay. Altogether, our study suggests that Cas proteins interact with proteins within and beyond the CRISPR Cas systems, and it provides a basis for the investigation of the potential roles of DNA repair proteins in the CRISPR Cas systems and/or vice versa.
Hille, Frank [Verfasser]. "Investigation of Spacer Acquisition Mechanisms in Type V-A CRISPR-Cas Systems / Frank Hille". Berlin : Humboldt-Universität zu Berlin, 2020. http://d-nb.info/1215570341/34.
Texto completoRibeiro, Mateus Cotta. "A reprodução crítica do espaço na porção meridional da Serra do Espinhaço de Minas Gerais: modernização do espaço e crise da sociedade do trabalho". Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/8/8136/tde-15012016-135253/.
Texto completoThis study deals with the social changes experienced by people from the southern area of Serra do Espinhaço, Minas Gerais, Brazil. These changes are related to the increase of the tourism industry however they are determined by crise o work society reproduction.
Cruz, Murilo Medici Navarro da. "Estado, espaço e acumulação na crise contemporânea". Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/8/8136/tde-20062007-153251/.
Texto completoThis work starts from a matter put by the current reality: The world economic crisis, specially seem on what has been denominated \"money predomination economy\" and, along with the crisis, the one of national State, both seen under the world\'s perspective and, equally, the Brazilian perspective. Nevertheless, this work does not intend, herein, to give a historical or purely economic treatment of the problem. Instead, what you will see is closer to an analytical and theoretical exercise. This work constitutes, firstly, of a deep discussion about the basis of capital economy which, according to what is understood, also are the basis of the current economic crisis. Secondly, to reflect about the economic crisis as much as politics, is necessary to reflect about the production of space and the State\'s role within the capitalist society. And thirdly, the union between the State and the capital shows itself identifiable on the national territory analysis along with your basis. Last but not least, the current crisis problem is put through a criticism to the lack of focusing the capital on a specific market, criticism that takes us to formulate the hypothesis of an abstract investment of capital, which would be a characteristic of the crisis itself.
Philipp, Carolin [Verfasser]. "Spaces of Resistance – Framing Crisis and Activism in Athens / Carolin Philipp". Kassel : Universitätsbibliothek Kassel, 2018. http://d-nb.info/1155948718/34.
Texto completoKreston, Nicholas Alexander. "Post-Keynesian financial spaces, places, and flows : geographies of finance and financial crisis". Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:3ea77af2-650c-456a-a4c2-5ee67c83d293.
Texto completoLibros sobre el tema "CRISPR spacers"
Martin, David. Crisis in space. New York: Ballantine Books, 1986.
Buscar texto completoCorporation, British Broadcasting, ed. Crisis in space. London: Severn House by arrangement with the British Broadcasting Corporation, 1986.
Buscar texto completoHolt, Michael. Crisis in space. New York: Ballantine Books, 1986.
Buscar texto completoill, Kinsella Pat, ed. Crisis. Minneapolis, MN: Magic Wagon, 2017.
Buscar texto completoNansen, Ralph. Energy crisis: Solution from space. Burlington, Ont: Apogee Books, 2009.
Buscar texto completoReis, Ronald A. Apollo 13: Crisis in space. New York: Chelsea House, 2012.
Buscar texto completoVitalidad y crisis en los espacios públicos de Sevilla. [Seville]: Diputación de Sevilla, 2006.
Buscar texto completoCabannes, Yves, Mike Douglass y Rita Padawangi, eds. Cities in Asia by and for the People. NL Amsterdam: Amsterdam University Press, 2018. http://dx.doi.org/10.5117/9789462985223.
Texto completoMaking Humanitarian Spaces Global: Coordinating Crisis Response through the Cluster Approach. [New York, N.Y.?]: [publisher not identified], 2012.
Buscar texto completoBouma, Geiske. Ruimtelijke ordening in crisis: Bijdragen aan de PlanDag 2010. Delft]: [Stichting Planologische Discussiedagen], 2010.
Buscar texto completoCapítulos de libros sobre el tema "CRISPR spacers"
Davison, Michelle y Devaki Bhaya. "Creation and Analysis of a Virome: Using CRISPR Spacers". En Methods in Molecular Biology, 307–16. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2687-9_20.
Texto completoDupuis, Marie-Ève, Rodolphe Barrangou y Sylvain Moineau. "Procedures for Generating CRISPR Mutants with Novel Spacers Acquired from Viruses or Plasmids". En Methods in Molecular Biology, 195–222. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2687-9_13.
Texto completoPallarés, Ana Morcillo. "Crisis and opportunity". En Manhattan's Public Spaces, 61–69. London: Routledge, 2021. http://dx.doi.org/10.4324/9781003198543-4.
Texto completoMokrousov, Igor y Nalin Rastogi. "Spacer-Based Macroarrays for CRISPR Genotyping". En Methods in Molecular Biology, 111–31. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2687-9_7.
Texto completoBurman, Erica. "Lockdown Vistas: Time, Space, Solidarity, Action". En The Psychology of Global Crises and Crisis Politics, 189–212. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-76939-0_9.
Texto completoJones, Martin y Kevin Ward. "Excavating the Logic of British Urban Policy: Neoliberalism as the “Crisis of Crisis-Management”". En Spaces of Neoliberalism, 126–47. Chichester, UK: John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781444397499.ch6.
Texto completoPallarés, Ana Morcillo. "Identity crisis: Lincoln Center and the High Line". En Manhattan's Public Spaces, 144–69. London: Routledge, 2021. http://dx.doi.org/10.4324/9781003198543-9.
Texto completoMartín-Moruno, Dolores. "Crisis? What Crisis? Making Humanitarian Crises Visible in the History of Emotions". En Making Humanitarian Crises, 1–28. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-00824-5_1.
Texto completoGouw, Arvin M. "CRISPR Challenges and Opportunities for Space Travel". En Human Enhancements for Space Missions, 19–34. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-42036-9_2.
Texto completoMaciocco, Giovanni y Silvano Tagliagambe. "The Aesthetic Crisis as the Crisis of the Glance". En People and Space, 13–18. Dordrecht: Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-1-4020-9879-6_3.
Texto completoActas de conferencias sobre el tema "CRISPR spacers"
Timkin, P. D. y A. A. Penzin. "An experimental approach for diagnosing cercosporosis using RPA+CRISPR/Cas12a". En II All-Russian (national) scientific conference with international participation "Russian Science, Innovation, Education". Krasnoyarsk Science and Technology City Hall, 2023. http://dx.doi.org/10.47813/rosnio-ii.2023.8.263-266.
Texto completoPernak, Elizaveta, Mariia Vladimirova, Viktoria Muntyan, Alexey Afonin y Marina Roumiantseva. "ANALYSIS OF CRISPR CASSETTE ELEMENTS IN NATIVE ISOLATES OF SINORHIZOBIUM MELILOTI ISOLATED IN THE CENTRAL ASIAN ORIGIN OF PLANT DIVERSITY". En 23rd SGEM International Multidisciplinary Scientific GeoConference 2023. STEF92 Technology, 2023. http://dx.doi.org/10.5593/sgem2023/6.1/s25.13.
Texto completoMuhlbauer, Rachel L., Kristen Turner, Finn Hiatt, Robert Dyer, Jeff Slostad y Robert P. Hoyt. "CRISSP: Customizable, Recyclable Launch Packaging". En AIAA SPACE 2016. Reston, Virginia: American Institute of Aeronautics and Astronautics, 2016. http://dx.doi.org/10.2514/6.2016-5243.
Texto completoTsafoulia, Loukia y Severino Alfonso. "Transient Spaces: Building Community in Crisis Contexts". En 2018 ACSA International Conference. ACSA Press, 2018. http://dx.doi.org/10.35483/acsa.intl.2018.1.
Texto completoBaryshev, Yurij. "Physics of Gravitational Interaction: Geometry of Space or Quantum Field in Space". En 1st CRISIS IN COSMOLOGY CONFERENCE, CCC-1. AIP, 2006. http://dx.doi.org/10.1063/1.2189130.
Texto completoWu, Wei-Zhi y You-Hong Xu. "Rough approximations of intuitionistic fuzzy sets in crisp approximation spaces". En 2010 Seventh International Conference on Fuzzy Systems and Knowledge Discovery (FSKD). IEEE, 2010. http://dx.doi.org/10.1109/fskd.2010.5569662.
Texto completoStranix, Katie. "Building Resiliency Through Small Scale Restorative Spaces". En 2022 AIA/ACSA Intersections Research Conference. ACSA Press, 2022. http://dx.doi.org/10.35483/acsa.aia.inter.22.12.
Texto completoTsafoulia, Loukia. "Transient Spaces: Building Community in Crisis Contexts Project". En 2018 ACSA International Conference. ACSA Press, 2018. http://dx.doi.org/10.35483/acsa.intl.2018.2.
Texto completoBachtarzi, Rym Mouni, Djamel Alkama y Hana Salah-Salah. "Urban Public Space in The Context of a New Era, Case of Annaba City-Algeria". En 4th International Conference of Contemporary Affairs in Architecture and Urbanism – Full book proceedings of ICCAUA2020, 20-21 May 2021. Alanya Hamdullah Emin Paşa University, 2021. http://dx.doi.org/10.38027/iccaua2021199n3.
Texto completoLasmane, Skaidrīte. "Including the Emotional Potential of Literature in Post-crisis Education". En 80th International Scientific Conference of the University of Latvia. University of Latvia Press, 2022. http://dx.doi.org/10.22364/htqe.2022.73.
Texto completoInformes sobre el tema "CRISPR spacers"
Castilleja Vargas, Liliana, Daniel Hernaiz, Alejandro Rasteletti y Eduardo Borensztein. International Crises and Policy Responses in the Southern Cone. Inter-American Development Bank, octubre de 2012. http://dx.doi.org/10.18235/0011434.
Texto completoMolloy, James P. Air and Space Expeditionary Force Crisis Action Leadership for Commanders. Fort Belvoir, VA: Defense Technical Information Center, abril de 2004. http://dx.doi.org/10.21236/ada434089.
Texto completoCuerden, Richard, Mary Williams, Jeanne Breen, Dan Campsal, Suzy Charman, David G. Davies, Nick Reed y Sarah Simpson. Safe Roads for All. TRL, agosto de 2021. http://dx.doi.org/10.58446/ohss3066.
Texto completoRebucci, Alessandro, Andrew Powell y Eduardo Fernández-Arias. The Multilateral Response to the Global Crisis: Rationale, Modalities, and Feasibility. Inter-American Development Bank, junio de 2009. http://dx.doi.org/10.18235/0010916.
Texto completoRomer, Christina y David Romer. Fiscal Space and the Aftermath of Financial Crises: How It Matters and Why. Cambridge, MA: National Bureau of Economic Research, abril de 2019. http://dx.doi.org/10.3386/w25768.
Texto completoAbed, Dana, Rihab Sawaya y Nadim Tabbal. Analyzing Voter Turnout in Lebanon: Political Change in Times of Crisis. Oxfam, abril de 2022. http://dx.doi.org/10.21201/2022.8823.
Texto completoSobhy, Hania. Reforms for Another Planet: The Global Learning Crisis, Political Drivers and Expert Views on Egypt’s Edu 2.0. Research on Improving Systems of Education (RISE), febrero de 2023. http://dx.doi.org/10.35489/bsg-rise-2023/pe06.
Texto completoTrapani, Paola. Collaborative Housing as a Response to the Housing Crisis in Auckland. Unitec ePress, julio de 2018. http://dx.doi.org/10.34074/ocds.0821.
Texto completoMontiel, Peter J. y Eduardo Fernández-Arias. Crisis Response in Latin America: Is the "Rainy Day" at Hand? Inter-American Development Bank, junio de 2009. http://dx.doi.org/10.18235/0010915.
Texto completoBonomo, Marco, Claudio R. Frischtak y Paulo Ribeiro. Public Investment and Fiscal Crisis in Brazil: Finding Culprits and Solutions. Inter-American Development Bank, abril de 2021. http://dx.doi.org/10.18235/0003199.
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