Acceder

Bibliografías temáticas / Contact dermatitis

Índice

Artículos de revistas
Tesis
Libros
Capítulos de libros
Actas de conferencias
Informes

Literatura académica sobre el tema "Contact dermatitis"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 9 de junio de 2025

Crea una cita precisa en los estilos APA, MLA, Chicago, Harvard y otros

Elija tipo de fuente:

Consulte las listas temáticas de artículos, libros, tesis, actas de conferencias y otras fuentes académicas sobre el tema "Contact dermatitis".

Junto a cada fuente en la lista de referencias hay un botón "Agregar a la bibliografía". Pulsa este botón, y generaremos automáticamente la referencia bibliográfica para la obra elegida en el estilo de cita que necesites: APA, MLA, Harvard, Vancouver, Chicago, etc.

También puede descargar el texto completo de la publicación académica en formato pdf y leer en línea su resumen siempre que esté disponible en los metadatos.

Artículos de revistas sobre el tema "Contact dermatitis"

1

Stumpfová, Alena. "Allergic contact dermatitis versus irritant contact dermatitis." Dermatologie pro praxi 17, no. 1 (March 28, 2023): 49–54. http://dx.doi.org/10.36290/der.2023.009.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

2

Marty, Chelsy L., and Janet F. Cheng. "Irritant Contact Dermatitis Precipitating Allergic Contact Dermatitis." Dermatitis (formerly American Journal of Contact Dermatitis) 16, no. 02 (2005): 087. http://dx.doi.org/10.2310/6620.2005.04028.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

3

Marty, Chelsy L., and Janet F. Cheng. "Irritant Contact Dermatitis Precipitating Allergic Contact Dermatitis." Dermatitis 16, no. 2 (June 2005): 87–88. http://dx.doi.org/10.1097/01206501-200506000-00006.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

4

Putri, Ike Puspitasari singgih, Tri Martiana, and Firman Suryadi Rahman. "Correlation between Environmental and Individual Factors with Dermatitis Contact on Tobacco Farmers." Indonesian Journal of Occupational Safety and Health 9, no. 1 (April 30, 2020): 95. http://dx.doi.org/10.20473/ijosh.v9i1.2020.95-103.

Texto completo

Resumen

Introduction: Contact dermatitis is inflammation caused by substance which attaches to the skin. This contact dermatitis is divided into two, which are irritant contact dermatitis and allergic contact dermatitis. The purpose of this study was to analyze the factors associated with the incidence of contact dermatitis that occurred in translucent farmers in Ambulu village, Ambulu District, Jember district. Methods: The type of this research was observational analytic research with a cross-sectional approach. The population in this study was 61 tobacco farmers of ambulu village, taken by simple random sampling technique to obtain 53 tobacco farmers. The independent variables in this study were tenure, the frequency of contact, the duration of contact and age. The dependent variable was contact dermatitis. The test used to determine whether there was a relationship was the Chi-Square test. The results of this study were the results of frequency analysis of tobacco farmer contacts having a p-value of 0.020 smaller than 0.05 it is means that there was a relationship. The duration of contact p-value of 0.000 smaller than 0.05 so that there was a relationship between contact time and contact dermatitis. For the work period variables, there was not a relationship with contact dermatitis with p-value 0.210 greater than 0.05, while for the results of the age analysis obtained a p-value of 0.455 so that there was no relationship between over and contact dermatitis. Conclusion: There is a relationship between the frequency of contact and the duration of contact with contact dermatitis whereas for the working period and age there is no relationship with contact dermatitis Keywords: contact dermatitis, tobacco farmers

Los estilos APA, Harvard, Vancouver, ISO, etc.

5

Jerajani, HR. "Contact dermatitis." Indian Journal of Dermatology, Venereology and Leprology 73, no. 5 (2007): 288. http://dx.doi.org/10.4103/0378-6323.35729.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

6

Nasir, Adnan, and Anthony A. Gaspari. "Contact dermatitis." Clinical Reviews in Allergy and Immunology 14, no. 2 (June 1996): 151–84. http://dx.doi.org/10.1007/bf02780197.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

7

Ahmed, Sara. "Contact dermatitis." InnovAiT: Education and inspiration for general practice 8, no. 11 (October 8, 2015): 653–59. http://dx.doi.org/10.1177/1755738015601448.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

8

Brasch, Jochen, Detlef Becker, Werner Aberer, Andreas Bircher, Birger Kränke, Stefanie Denzer-Fürst, and Axel Schnuch. "Contact Dermatitis." JDDG 5, no. 10 (October 2007): 943–51. http://dx.doi.org/10.1111/j.1610-0387.2007.06523.x.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

9

Verma, Vineeta, and SN Shah. "Contact Dermatitis." InnovAiT: Education and inspiration for general practice 2, no. 6 (June 2009): 336–41. http://dx.doi.org/10.1093/innovait/inp033.

Texto completo

Resumen

Approximately 15% of GP consultations in the UK are for a skin condition. In the general population, about 4.5% of people have a contact allergy to nickel and 1–3% to an ingredient in cosmetics. Studies suggest that skin disorders (29%) are the second most common cause of occupational disease after musculoskeletal conditions (57%).

Los estilos APA, Harvard, Vancouver, ISO, etc.

10

Rose, Karen. "Contact Dermatitis." Journal of Audiovisual Media in Medicine 27, no. 3 (September 2004): 130. http://dx.doi.org/10.1080/01405110412331284325.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

Más fuentes

Tesis sobre el tema "Contact dermatitis"

1

Hayakawa, Ritsuko. "Contact Dermatitis." Nagoya University School of Medicine, 2000. http://hdl.handle.net/2237/5356.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

2

Reis, Felipe Rovere Diniz 1979. "Dermatite alergica de contato ocupacional = perfil clinico-epidemiologico dos pacientes atendidos no ambulatorio de medicina do trabalho da Unicamp." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310058.

Texto completo

Resumen

Orientador: Jose Inacio de Oliveira<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-15T19:21:40Z (GMT). No. of bitstreams: 1 Reis_FelipeRovereDiniz_M.pdf: 3469626 bytes, checksum: 9ef6c34f776f70e4620230f3b66bd0f4 (MD5) Previous issue date: 2010<br>Resumo: Diversos estudos descrevem o perfil clínico-epidemiológico e os resultados dos testes de contato das populações atendidas com suspeitas de dermatite alérgica de contato. Alguns evidenciam a provável relação causal com o trabalho; outros alertam para a necessidade de repetição do teste quando ocorrem múltiplas reações, principalmente nas demandas trabalhistas. O objetivo foi analisar o perfil clínico-epidemiológico e os resultados dos testes de contato dos pacientes com suspeita de dermatite alérgica de contato ocupacional atendidos no Ambulatório de Medicina do Trabalho da Universidade Estadual de Campinas. Foi realizado um estudo descritivo transversal retrospectivo com pacientes atendidos entre 1 de janeiro de 1999 e 31 de dezembro de 2008, envolvendo as seguintes variáveis: idade, cor, sexo, ocupação, tempo na ocupação, agente referido como sensibilizante, local inicial do eczema, origem do encaminhamento, resultados dos testes de contato e nexo causal. Foram analisados 180 prontuários e os resultados mostraram que o perfil clínicoepidemiológico foi semelhante àqueles referidos na literatura, mas os índices desensibilização foram proporcionalmente maiores: 85% dos pacientes tiveram pelo menos uma reação positiva no primeiro teste de contato, a média de reações positivas por teste foi 3,38 e 68% dos testes positivos apresentaram mais de duas reações positivas. Os elevados índices de sensibilização e a existência simultânea de múltiplas reações na maioria dos pacientes podem ser explicados por condições predisponentes para polissensibilização - dermatite nas mãos cronificadas por repetidas exposições ocupacionais - e/ou pela interpretação de reações irritativas como reações positivas. Foi sugerida, então, uma Ficha de Coleta de Dados, a ser preenchida durante as avaliações clínicas e a repetição dos testes de contato quando ocorrerem mais de 2 reações positivas relevantes a substâncias não correlacionada<br>Abstract: Several studies describe the clinical and epidemiological profile and the results of patch tests of the targeted population with suspected allergic contact dermatitis. Some evidence the probable causal relationship to work; others warn of the need to repeat tests when multiple reactions occur, especially in the lawsuits. The objetive was to analyze the clinical and epidemiological profile and the results of patch tests of patients with suspected allergic contact dermatitis treated at the Campinas State University's Occupational Medicine Clinic. We conducted a retrospective cross-sectional study with patients treated between January 1, 1999 and December 31, 2008 involving the following variables: age, race, sex, occupation, time in occupation, sensitizing agent, eczema locus, referral source, results of patch tests and causal relationship. We analyzed 180 medical records and the results show that clinical and epidemiological profile was similar to those reported in the literature, but the rates of awareness were proportionally larger: 85% of patients had at least one positive reaction in the first patch test, the average of positive reactions per test was 3.38 and 68% dos positive tests had more than two positive reactions. High levels of sensitization and the simultaneous existence of multiple reactions in most patients can be explained by predisposing factors to polysensization - cronic dermatitis on the hands caused by repeated occupational exposure - and/or by the interpretation of irritant reactions as positive reactions. It has been suggested then a sheet data collection to use in the clinic evaluation that includes the repetition of tests when more than 2 relevant positive reactions occurred to substances not correlated<br>Mestrado<br>Epidemiologia<br>Mestre em Saude Coletiva

Los estilos APA, Harvard, Vancouver, ISO, etc.

3

Kerr, Alastair. "Photoallergic contact dermatitis in Europe." Thesis, University of Dundee, 2012. https://discovery.dundee.ac.uk/en/studentTheses/8202b022-08c8-4714-b85f-e231e474f8b8.

Texto completo

Resumen

Photoallergic contact dermatitis (PACD) is a clinical problem that has often been poorly understood and neglected by dermatologists over recent years. This can be partly attributed to its investigation by photopatch testing (PPT) falling between the expertise of photobiologists and contact dermatitis clinicians. One result of this situation was that no European Baseline PPT series had been agreed on. To redress this, the European multi centre photopatch test study (EMCPPTS) was conceived to provide up to date information on which photoallergens are of greatest clinical relevance. Its conduct and results form the core research project of this thesis. To enable the EMCPPTS to proceed and its results to be viewed in a wider context, the other Chapters of this thesis explore important related aspects of PACD and PPT in Europe. The introduction examines the nature of PACD and PPT and reviews current photoallergens. Then, the investigation of the two photoallergens carprofen and chlorproethazine by PPT is recounted. These studies highlight deficiencies within the current European regulatory system for preventing photoallergens from reaching the marketplace, as well as providing templates for the investigation of new photoallergens in the human environment. This is followed by a pilot PPT study which provides new information on the optimum non-irritating concentration of the 19 ultraviolet sunscreen absorbers to be used in the EMCPPTS. The issue of attempting to determine the photoallergenic potential of the EMCPPTS agents with respect to exposure patterns is addressed by conducting a sunscreen survey in the UK. The EMCPPTS itself is then detailed, as well as the difficulties that can be encountered when conducting a large clinical study of this nature. The results from the EMCPPTS and other presented studies were shown to be of importance in deciding upon a new European Baseline PPT series. The process involved in deciding this series, as well as its content are described before overall conclusions and possible future studies in the domain of PACD and PPT are discussed.

Los estilos APA, Harvard, Vancouver, ISO, etc.

4

Lampe, Kenneth F. "Contact Dermatitis from Sonoran Desert Plants." University of Arizona (Tucson, AZ), 1986. http://hdl.handle.net/10150/609073.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

5

Bensefa-Colas, Lynda. "Analyse des dermatoses professionnelles au sein du réseau national de vigilance et de prévention des pathologies professionnelles (RNV3P) : distribution, tendances et situations professionnelles à risque." Thesis, Sorbonne Paris Cité, 2015. http://www.theses.fr/2015USPCB155.

Texto completo

Resumen

Contexte : Les dermatoses professionnelles sont l’une des principales causes de pathologies professionnelles en Europe, et dans près de 80% des cas, elles concernent des dermatites de contact professionnelles (DCP). Les DCP comprennent les dermatites allergiques de contact (DAC), les dermatites irritatives de contact (DIC) et les urticaires de contact (UC). En France, les secteurs et nuisances à risque de DCP et les tendances chronologiques de DCP sont très peu documentés. Objectifs : 1) étudier les tendances observées au fil du temps vis-à-vis du nombre de cas de dermatoses professionnelles, des secteurs d’activité concernés et des nuisances mises en cause, 2) mettre en évidence des secteurs ou des postes à risque de dermatoses professionnelles. Méthode : Ce travail de thèse s’appuie sur le réseau français RNV3P (Réseau national de vigilance et de prévention des pathologies professionnelles) qui assure le suivi des évènements de santé liés au travail sur l’ensemble du territoire, en centralisant les informations recueillies dans ses 32 centres de consultations de pathologies professionnelles (CCPP). Les analyses ont porté sur les DAC, les DIC et les UC en lien probable ou certain avec le travail et recensées dans le RNV3P entre 2001 et 2010. L’analyse des évolutions temporelles a été réalisée à partir des rapports de cote de signalement (Reporting Odds-Ratio, ROR). Deux méthodes statistiques ont été utilisées : le coefficient de corrélation de rang de Kendall sur les ROR estimés chaque année et le modèle logistique calculant la variation annuelle des cas. Résultats : Les 5990 cas de DCP notifiés touchent plus fréquemment les femmes, dans des tranches d'âges jeunes. Les principaux secteurs mis en cause pour les trois DCP se distribuent différemment en fonction du sexe et sont, par ordre décroissant de fréquence : santé et action sociale, services personnels, construction, métallurgie et travail des métaux, administrations publiques, services fournis principalement aux entreprises, commerce et réparation automobile, hôtellerie et restauration. Les DCP associées aux cosmétiques (savons ou substances parfumantes) et les biocides augmentent significativement dans le secteur de la santé et de l’action sociale ; les produits de coiffure et les cosmétiques (savons essentiellement) augmentent dans celui des services personnels, essentiellement parmi les coiffeuses. On observe une montée des cas de DAC aux résines époxy dans la construction sur la période et les DIC liées au ciment dans ce secteur ne baissent pas. Les cas de DAC aux métaux augmentent dans le secteur des services fournis aux entreprises (personnels de nettoyage). Nos résultats ont aussi montré une hausse des DAC liées aux isothiazolinones, quel que soit le secteur (+38%) et une baisse des DIC liées à l’action de lavage des mains (utilisation itérative des savons). Par ailleurs, nos données ont objectivé l’impact de mesures réglementaires ou de politiques visant à prévenir les DCP : la mise en place de la directive européenne « Ciment » (2003/53/CE) en 2005 s’est accompagnée d’une réduction de moitié des cas de DAC et une baisse similaire a été observée à partir des données du réseau britannique EPIDERM, confortant nos conclusions ; la campagne de substitution des gants en latex dans le secteur de soins au milieu des années 2000 est suivie d’une réduction significative de la notification des cas d’UC. Conclusion : Ces résultats démontrent, avec l’exemple des dermatoses professionnelles, la capacité du RNV3P à orienter les politiques nationales en matière de prévention des risques professionnels et à en évaluer l’efficacité<br>Background: In Europe, occupational skin disease is one of the major causes of work-related diseases, among them occupational contact dermatitis (OCD) accounts for 80% of all cases of OSD reported, but data about sectors and agents at risk remains sparse. Objectives: 1) to study OCD trends in terms of industrial activities and main causal agents, 2) to describe industrial sectors or occupations at risk of OCD. Method: Data were collected from the French National Network of Occupational Disease Surveillance and Prevention (RNV3P) during 2001-2010 period, based on the 32 French Occupational and Environmental Disease Consultation Centres. All allergic contact dermatitis (ACD), irritative contact dermatitis (ICD) and contact urticaria (CU) probably or certainly work-related were included in the study. Trends were examined (i) on annual crude numbers of OCD and (ii) on reported odds-ratios of OCD calculated using logistic regression models. Results: 5990 OCD cases were included and concerned more frequently young age classes among women and older age classes among men. Industrial sectors more commonly involved in OCD concerned in decreasing order: health and social work activities, personal service activities, construction, metal industry, public administrations, other business activities, retail trade and repair of motor vehicles, and hotels and restaurants. According to trend analysis of OCD cases, cosmetics (including soaps and fragrances) and biocides increased significantly in health and social work activities; hairdressing products and cosmetics (mainly soaps) in personal service activities (including primarily hairdressers). In construction sector, ACD due to epoxy resins increased during the study period and concomitantly, ICD attributed to cement did not decrease underlying the lack of prevention in this sector at risk. ACD due to metals increased in other business activities mainly occupied by cleaning staff. We showed a rise of ACD due to isothiazolinone compounds whatever the sector. Besides, we have shown the impact of regulatory measures or prevention campaign on OCD: (i) a significant reduction by almost half in the occurrence of ACD attributed to chromate in cement which coincides with the implementation of the European Cement directive and we obtained similar results to a study based on the UK EPIDERM network; (ii) the effectiveness of latex exposure prevention measures for health care workers since half of 2000s and (iii) the wide use of disinfection with an alcohol-based solution in health and social work activity followed by a significant reduction of ICD due to iterative handwashing with soap. Conclusion: RNV3P data allowed to highlight causal agents involved in sectors most at risk of OCD. These results might help intervention policy in health and safety at work and allergy prevention. They also showed the effectiveness of preventative intervention on OCD, suggesting that RNV3P reporting scheme is useful in France to evaluate intervention policy in health and safety at work

Los estilos APA, Harvard, Vancouver, ISO, etc.

6

Beliauskienė, Aistė. "Dermatitu sergančių pacientų įsijautrinimo kontaktiniams alergenams ir su juo susijusių veiksnių tyrimas." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2012. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120214_092202-76017.

Texto completo

Resumen

Darbo tikslas – įvertinti dermatitu sergančių pacientų įsijautrinimą kontaktiniams alergenams ir su juo susijusius veiksnius. Darbo uždaviniai: 1. Nustatyti įsijautrinimo kontaktiniams alergenams dažnumą tarp dermatitu sergančių pacientų. 2. Įvertinti įsijautrinimo kontaktiniams alergenams dažnumo sąsajas su tiriamųjų amžiumi, lytimi ir profesija. 3. Nustatyti įsijautrinimo kontaktiniams alergenams klinikos ypatumus. 4. Įvertinti įsijautrinimo kontaktiniams alergenams sąsajas su atopiniu dermatitu, lėtine (-ėmis) kojos (-ų) opa (-omis) ir kitais veiksniais. Išvados: 1. Kontaktiniams alergenams įsijautrinę pusė dermatitu sergančių pacientų, dažniausiai – metalui nikeliui (17,1 proc.). Iš aromatinių medžiagų dažniausias yra įsijautrinimas Peru balzamui (8 proc.). Į pagrindinį alergenų rinkinį neįtrauktini retai (0,1 proc.) nustatyti alergenai: gumų medžiagos merkaptobenzotiazolas ir N-zopropil-N’-fenil-parafenilendiaminas. 2. Įsijautrinimas kontaktiniams alergenams jaunesniems nei 40 metų dermatitu sergantiems pacientams pasireiškia du kartus dažniau nei vyresniems, o moterims – du kartus dažniau nei vyrams. Žemės ūkio ir miškininkystės darbuotojai kontaktiniams alergenams įsijautrinę tris kartus dažniau nei kiti dirbantieji. Vertinant atskirus alergenus, jaunesni nei 40 metų pacientai dažniau nei vyresni yra įsijautrinę nikeliui, kobaltui ir kvaterniumui-15, o 40 metų ir vyresni – Peru balzamui, kanifolijai, aromatų mišiniui I, lanolinui, seskviterpenlaktonams ir... [toliau žr. visą tekstą]<br>The aim of the study: To evaluate contact sensitization and its associated factors in patients with dermatitis. The objectives of the study: 1. To determine the frequency of sensitization to contact allergens in patients with dermatitis. 2. To evaluate associations between the frequency of sensitization to contact allergens and age, sex and occupation in patients with dermatitis. 3. To determine clinical features of contact sensitization. 4. To evaluate associations between sensitization to contact allergens and atopic dermatitis, chronic leg ulcers and other factors. CONCLUSIONS 1.Half of the patients with dermatitis were sensitized to contact allergens, most frequently to metal nickel (17.1%). From the fragrances, bal¬sam of Peru was the most frequent contact allergen (8%). Rare allergens that should not be included in the baseline series are the substances present in the composition of rubber – mercaptobenzothiazole and N-isopropyl-N'-phenyl-p-phenylene diamine (IPPD). 2.Patients under 40 years of age are two times more frequently sensitized than the older ones. In women contact allergy is twice as more frequent as in men. Agricultural and forestry workers are sensitized to contact allergens three times as more often as other employees. What regards individual allergens, among patients under 40 years of age sensitization to nickel, cobalt and quaternium-15 is more prevalent than in the older ones. Among patients who are 40 years of age and over contact sensitization to... [to full text]

Los estilos APA, Harvard, Vancouver, ISO, etc.

7

Gentry, Retha D., Lisa Ousley, and Candice N. Short. "Nickel Allergic Contact Dermatitis: A Case Report." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/7159.

Texto completo

Resumen

A 22-year-old male college student presented to primary care with a pruritic rash on his mid abdomen for the past 2 weeks. He reported mild to moderate pruritus and had been scratching the area above his belt buckle.

Los estilos APA, Harvard, Vancouver, ISO, etc.

8

Mikulowska, Anna. "The human langerhans cell in irritant contact dermatitis." Lund : Dept. of Medical Cell Research, Lund University, 1994. http://catalog.hathitrust.org/api/volumes/oclc/39693813.html.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

9

Kuzmina, Natalia. "Biophysical aspects of contact dermatitis and its prevention /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-767-3/.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

10

Spriggs, Sandrine. "The role of glutathione in Allergic Contact Dermatitis." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3012684/.

Texto completo

Resumen

Allergic Contact Dermatitis is a skin condition that affects up to twenty percent of the North American and Western European population. The molecular initiating event (MIE) of this type IV delayed hypersensitivity is the formation of antigenic species by covalent modification of endogenous proteins. Cysteine residues, though not the most prevalent residues in skin proteins, are prone to react with small electrophilic molecules and thus play a crucial role in protein haptenation. The role of cysteine is also very prominent in removal of electrophiles. Glutathione (GSH) is the most prominent antioxidant in cells and contains a cysteine residue, providing a free reactive thiol for GSH conjugation of electrophiles and their subsequent removal. It is also the co-factor of an important set of enzymes involved in the metabolic clearance system, glutathione S-transferases (GST). However, it remains unclear whether the reactivity of small exogenous electrophiles with intracellular GSH could be a key factor in determining the epidermal bioavailability of sensitising chemicals. GST activity has been demonstrated both in skin and in most in vitro skin equivalents but so far studies have focussed on specific chemical clearance. The GSH cycle (synthesis, conjugation, recycling) has not been comprehensively studied in the HaCaT cell line, which is often used as a surrogate model for human skin. We showed that the model sensitisers 2,4-dinitrohalobenzenes, reacting with thiols via a SNAr mechanism, depleted intracellular GSH within the first hour of exposure in HaCaT cells, in a dose dependent manner. Synthesis of de novo GSH was investigated 24 hours after treatment with a single non-toxic dose of 10 μM of three dinitrohalobenzenes. GSH concentration was found similar or slightly higher than the level measured in control cells for 1-chloro-2,4-dinitrobenzene (DNCB) and 1-fluoro-2,4-dinitrobenzene (DNFB) but not for 1- bromo-2,4-dinitrobenzene (DNBB), which appeared to partially prevent GSH repletion. This data inferred that the repletion step was the differentiating factor between chemicals belonging to the same reactivity domain. The toxicity of the halogen released in the cells was most likely the reason for observing these differences and this might have been missed if only the clearance kinetics were investigated. Activation of the nuclear factor E2-related factor 2 (Nrf2) pathway was concomitantly observed for all compounds within two hours, and at concentrations less than 10 μM. Nrf2 activation is the precursor event for the overproduction of Phase II metabolic enzymes such as GSTs, enzymes involved in the synthesis of GSH such as Glutamyl cysteine ligase (GCL) and Glutathione synthetase (GS) as well as GSH related enzymes acting against oxidative stress such as Glutathione Reductase (GR). HaCaT cells treated with the model aldehydes benzaldehyde and phenylacetaldehyde, which oxidised cysteine residues in chemico, did not suffer a significant depletion of GSH levels at sub-toxic concentrations. In addition, these aldehydes have been shown to react with amines via a Schiff base mechanism to form stable protein adducts. Our set of data indicated that the Schiff base mechanism was most probably favoured and that an oxidation of GSH (a reduction of the GSH:GSSG ratio), was effectively and rapidly controlled by GR activity. The volatility of aldehydes was likely to limit the bioavailability of these compounds intracellularly, possibly increasing the probability of haptenation with cell membrane proteins. Skin sensitisers are often defined by their potency (ranging from extreme to non-sensitising) rather than their chemical reactivity domain. We compared the clearance of two extreme sensitisers by the GSH pathway: DNCB and diphenylcyclopropenone (DPCP). We demonstrated that two chemicals able to react with thiols in chemico via different mechanisms (SNAr for DNCB and Michael addition for DPCP) were affecting GSH levels differently in HaCaT cells. DNCB induced GSH depletion at non-toxic concentrations, while exposure to DPCP decreased cell viability at concentrations for which GSH stock was not significantly reduced. DPCP reactivity with thiols has been suggested in cell membranes. Contrary to the results obtained for DPCP, diethyl maleate (DEM), a moderate sensitiser also reacting via Michael addition, was cleared by GSH at a rate similar to the rate of de novo GSH synthesis, masking the overall depletion of GSH. Exposure to DEM induced an overproduction of GSH after 24 hours that was more pronounced than the one observed for the more potent sensitiser DNCB, showing that the sensitising potency of chemicals could not be correlated solely to the ability to be conjugated by GSH (i.e. weak sensitisers would be cleared rapidly while potent sensitisers would not). These experiments demonstrated that the defence mechanisms in the HaCaT cell line were providing a rapid response to chemical stress. To investigate the effects of chemical exposure on GSH lifecycle in reconstructed human epidermis (RHE), we attempted repeated cycles of 2 hour exposure to DNCB over a week long period. For three consecutive treatments, each exposure to DNCB led to GSH depletion. Replenishment to basal level was observed after a 22 hour recovery period. Accumulation of Nrf2 in the cytosol also occurred within the two hours of exposure to DNCB but returned to baseline during each recovery period. The amount of GSH conjugate formed (dinitrophenyl glutathione) increased after each exposure, suggesting that the metabolic capacity of skin may be enhanced in response to exposure to exogenous compounds. In conclusion, the GSH cycle is fully active in skin and participates in the clearance of some exogenous compounds with electrophilic properties. GSH skin metabolism can also potentially be enhanced after repeated exposures to small quantities of electrophiles. Future risk assessments for skin sensitisation potential of topically applied chemicals could integrate these findings to correlate more realistically to in vivo scenarios.

Los estilos APA, Harvard, Vancouver, ISO, etc.

Más fuentes

Libros sobre el tema "Contact dermatitis"

1

Frosch, Peter J., Torkil Menné, and Jean-Pierre Lepoittevin, eds. Contact Dermatitis. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/3-540-31301-x.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

2

Johansen, Jeanne Duus, Vera Mahler, Jean-Pierre Lepoittevin, and Peter J. Frosch, eds. Contact Dermatitis. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-72451-5.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

3

Johansen, Jeanne Duus, Peter J. Frosch, and Jean-Pierre Lepoittevin, eds. Contact Dermatitis. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-03827-3.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

4

Management, Association of Domestic. Contact dermatitis. Wylam, Northumberland: The Association, 1990.

Buscar texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

5

Lepoittevin, Jean-Pierre, David A. Basketter, An Goossens, and Ann-Therése Karlberg, eds. Allergic Contact Dermatitis. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-80331-4.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

6

Angelini, Gianni, Domenico Bonamonte, and Caterina Foti, eds. Clinical Contact Dermatitis. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-49332-5.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

7

1938-, Jackson Edward M., and Goldner Ronald, eds. Irritant contact dermatitis. New York: M. Dekker, 1990.

Buscar texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

8

L, Rietschel Robert, Fowler Joseph F, and Fisher Alexander A. 1905-, eds. Fisher's contact dermatitis. 4th ed. Baltimore: Williams & Wilkins, 1995.

Buscar texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

9

Rycroft, Richard J. G., Torkil Menné, and Peter J. Frosch, eds. Textbook of Contact Dermatitis. Berlin, Heidelberg: Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-662-03104-9.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

10

Rycroft, Richard J. G., Torkil Menné, Peter J. Frosch, and Claude Benezra, eds. Textbook of Contact Dermatitis. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-662-13119-0.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

Más fuentes

Capítulos de libros sobre el tema "Contact dermatitis"

1

Jeong, Jong Yeong. "Allergic Contact Dermatitis, Contact Dermatitis." In Dermatology Diaries, 247–51. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-1578-7_61.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

2

Kiselova, Katyrena, and John J. Russell. "Contact Dermatitis." In Common Dermatologic Conditions in Primary Care, 41–48. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-18065-2_5.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

3

Martin, Stefan F., and Thilo Jakob. "Contact Dermatitis." In Clinical and Basic Immunodermatology, 411–29. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-29785-9_23.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

4

Gola, Massimo, Angelo Massimiliano D’Erme, and Martin Röcken. "Contact Dermatitis." In European Handbook of Dermatological Treatments, 159–71. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-45139-7_16.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

5

Norman, Robert A., and Edward M. Young. "Contact Dermatitis." In Atlas of Geriatric Dermatology, 21–28. London: Springer London, 2013. http://dx.doi.org/10.1007/978-1-4471-4579-0_2.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

6

Hjorth, N., J. M. Lachapelle, E. Schöpf, and D. V. Belsito. "Contact Dermatitis." In Dermatology in Five Continents, 387–88. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-83360-1_50.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

7

Enk, A. H., and J. Knop. "Contact Dermatitis." In Strategies for Immunointerventions in Dermatology, 273–81. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60752-3_24.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

8

Alexis, Ama, and Vincent A. DeLeo. "Contact Dermatitis." In Skin of Color, 37–43. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-0-387-84929-4_3.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

9

Angelini, Gianni, and Eustachio Nettis. "Contact Dermatitis." In Practical Guide to Patch Testing, 1–4. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-33873-2_1.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

10

Kanerva, L., and A. I. Lauerma. "Contact dermatitis." In European Handbook of Dermatological Treatments, 106–14. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-662-07131-1_17.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

Actas de conferencias sobre el tema "Contact dermatitis"

1

Vitorio, Rayssa Peixoto, Anny Bitencourt Oliveira, Ana Paula Honório Abreu, and Jaci José de Souza Junior. "DERMATITI DE CONTATO ASSOCIADA A INCONTINÊNCIA URINÁRIA/FECAL: FATORES RELACIONADOS E SEUS DESAFIO." In IX Congresso Acadêmico-Científico do UNIFESO, 236. Recife, Brasil: Even3, 2024. https://doi.org/10.29327/1449322.9-81.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

2

Ozgur, EA, Y. Demıral, and AH Cımrın. "714 Occupational contact dermatitis." In 32nd Triennial Congress of the International Commission on Occupational Health (ICOH), Dublin, Ireland, 29th April to 4th May 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/oemed-2018-icohabstracts.147.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

3

Sinitchi, Georgeta, Diana Costin, and Smaranda Diaconescu. "Nickel and contact dermatitis of children." In 2015 E-Health and Bioengineering Conference (EHB). IEEE, 2015. http://dx.doi.org/10.1109/ehb.2015.7391507.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

4

Fedorowicz, A., H. Singh, and E. Demchuk. "375. QSAR Models of Allergic Contact Dermatitis." In AIHce 2004. AIHA, 2004. http://dx.doi.org/10.3320/1.2758411.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

5

Panagiotidis, Kyriakos S., Ioannis A. Vezakis, Aikaterini Kyritsi, Anna Tagka, Ioannis Kakkos, and George K. Matsopoulos. "Allergic Contact Dermatitis Detection with Machine Learning." In 2023 International Conference on Computational Science and Computational Intelligence (CSCI). IEEE, 2023. http://dx.doi.org/10.1109/csci62032.2023.00225.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

6

Huliieva, Visala, and Nataliia Loienko. "RISK OF CONTACT DERMATITIS IN HEALTHCARE WORKERS." In Science, Technology, Innovation: Current Issues of Theory and Practice. Publishing House “Baltija Publishing”, 2024. https://doi.org/10.30525/978-9934-26-498-6-9.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

7

Kezic, Sanja. "1605a Individual susceptibility to work-related contact dermatitis." In 32nd Triennial Congress of the International Commission on Occupational Health (ICOH), Dublin, Ireland, 29th April to 4th May 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/oemed-2018-icohabstracts.251.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

8

Kezic, Sanja. "1605 Application of biomarkers in work-related contact dermatitis." In 32nd Triennial Congress of the International Commission on Occupational Health (ICOH), Dublin, Ireland, 29th April to 4th May 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/oemed-2018-icohabstracts.250.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

9

Goldenberg, Alina, Janice Lucille Pelletier, and Sharon Jacob. "Pediatric Allergic Contact Dermatitis—quality Improvement via a Registry Model." In Selection of Abstracts From NCE 2016. American Academy of Pediatrics, 2018. http://dx.doi.org/10.1542/peds.141.1_meetingabstract.00.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

10

Stoleski, S., J. Karadzinska-Bislimovska, J. Minov, D. Mijakoski, D. Stojanovski, and A. Atanasovska. "557 Contact dermatitis among workers occupationally exposed to ferronickel alloys." In 32nd Triennial Congress of the International Commission on Occupational Health (ICOH), Dublin, Ireland, 29th April to 4th May 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/oemed-2018-icohabstracts.160.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

Informes sobre el tema "Contact dermatitis"

1

wang, xiaoxue, Xiang Pu, Guanwei Fan, Xia Chen, ying Tang, nana wu, and jiangli luo. Clinical Effectiveness and Safety of TCM Oral Administration for the Treatment of Allergic Contact Dermatitis: A Meta Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2023. http://dx.doi.org/10.37766/inplasy2023.11.0037.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

2

Health hazard evaluation report: HETA-2007-0261-3122, evaluation of contact dermatitis among ink ribbon manufacturing employees - New York. U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, March 2011. http://dx.doi.org/10.26616/nioshheta200702613122.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

3

Health hazard evaluation report: HETA-2006-0155-3072, evaluation of contact dermatitis among machinists at an automotive parts manufacturer, Dana Corporation, Bristol, Virginia. U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, October 2008. http://dx.doi.org/10.26616/nioshheta200601553072.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

Ofrecemos descuentos en todos los planes premium para autores cuyas obras están incluidas en selecciones literarias temáticas. ¡Contáctenos para obtener un código promocional único!