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Literatura académica sobre el tema "Consensus sequence"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 25 de julio de 2025

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Artículos de revistas sobre el tema "Consensus sequence"

1

Burke, Kelly, Supriya Munshaw, William Osburn, et al. "HCV genotype 1a representative sequence elicits broad CD8+ T cell responses (113.10)." Journal of Immunology 188, no. 1_Supplement (2012): 113.10. http://dx.doi.org/10.4049/jimmunol.188.supp.113.10.

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Abstract Vaccines designed to prevent or to treat hepatitis C viral infection must achieve maximum cross-reactivity against widely divergent circulating strains. Computer-generated sequences minimize genetic distance between circulating strains, and can be generated as a consensus sequence (most common amino acid at each position) or a representative sequence (derived with Bayesian and maximal likelihood phylogenetic tools). Broad recognition of such sequences in HCV has not been demonstrated. Consensus and representative sequences were generated from 390 full-length HCV genotype 1a polypeptid

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2

Holmes, S. G., and M. M. Smith. "Interaction of the H4 autonomously replicating sequence core consensus sequence and its 3'-flanking domain." Molecular and Cellular Biology 9, no. 12 (1989): 5464–72. http://dx.doi.org/10.1128/mcb.9.12.5464-5472.1989.

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Yeast autonomously replicating sequence (ARS) elements are composed of a conserved 11-base-pair (bp) core consensus sequence and a less well defined 3'-flanking region. We have investigated the relationship between the H4 ARS core consensus sequence and its 3'-flanking domain. The minimal sequences necessary and sufficient for function were determined by combining external 3' and 5' deletions to produce a nested set of ARS fragments. Sequences 5' of the core consensus were dispensable for function, but at least 66 bp of 3'-flanking domain DNA was required for full ARS function. The importance

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3

Holmes, S. G., and M. M. Smith. "Interaction of the H4 autonomously replicating sequence core consensus sequence and its 3'-flanking domain." Molecular and Cellular Biology 9, no. 12 (1989): 5464–72. http://dx.doi.org/10.1128/mcb.9.12.5464.

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Yeast autonomously replicating sequence (ARS) elements are composed of a conserved 11-base-pair (bp) core consensus sequence and a less well defined 3'-flanking region. We have investigated the relationship between the H4 ARS core consensus sequence and its 3'-flanking domain. The minimal sequences necessary and sufficient for function were determined by combining external 3' and 5' deletions to produce a nested set of ARS fragments. Sequences 5' of the core consensus were dispensable for function, but at least 66 bp of 3'-flanking domain DNA was required for full ARS function. The importance

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4

Bae, J., U. R. Desai, A. Pervin, E. E. O. Caldwell, J. M. Weiler, and R. J. Linhardt. "Interaction of heparin with synthetic antithrombin III peptide analogues." Biochemical Journal 301, no. 1 (1994): 121–29. http://dx.doi.org/10.1042/bj3010121.

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Heparin-binding proteins may contain specific patterns of basic amino acids, called consensus sequences, that interact with heparin. Small peptides were synthesized that contained consensus sequences (i.e. FAKLNCRLYRKANKSSK) or disrupted consensus sequences (i.e. K136-->A) based on the known sequence of antithrombin III (amino acid residues 123-139). These peptides were then examined in both competitive and non-competitive binding experiments using bioassays, fluorescence spectroscopy, affinity chromatography and n.m.r. spectroscopy. Both the consensus and disrupted-consensus peptide bound

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5

TORSHIN, Ivan. "Direct and reversed amino acid sequence pattern analysis: structural reasons for activity of reversed sequence sites and results of kinase site mutagenesis." Biochemical Journal 345, no. 3 (2000): 733–40. http://dx.doi.org/10.1042/bj3450733.

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During studies of kinase phosphorylation, not all functional kinase phosphorylation may be found using consensus sequence patterns. This type of phosphorylation is termed ‘non-consensus’ or ‘cryptic’ phosphorylation. Results presented here based on molecular dynamics of short peptides show that protein kinases may phosphorylate not only established consensus sequences (reading a sequence from N-terminus to C-terminus) but also reversed consensus sequences (reading from C- to N-terminus). Several protein sequences were analysed and corresponding biochemical data were presented. Similarity of mo

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6

Yeh, Ren-Hwa, Tae Ryong Lee, and David S. Lawrence. "From Consensus Sequence Peptide to High Affinity Ligand, a “Library Scan” Strategy." Journal of Biological Chemistry 276, no. 15 (2001): 12235–40. http://dx.doi.org/10.1074/jbc.m011232200.

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A wide variety of proteins have been shown to recognize and bind to specific amino acid sequences on other proteins. These sequences can be readily identified using combinatorial peptide libraries. However, peptides containing these preferred sequences (“consensus sequence peptides”) typically display only modest affinities for the consensus sequence-binding site on the intact protein. In this report, we describe a parallel synthesis strategy that transforms consensus sequence peptides into high affinity ligands. The work described herein has focused on the Lck SH2 domain, which binds the cons

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7

Du Toit, Andrea. "A consensus pausing sequence." Nature Reviews Microbiology 12, no. 6 (2014): 394. http://dx.doi.org/10.1038/nrmicro3286.

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Palca, Joseph. "No consensus on sequence." Nature 322, no. 6078 (1986): 397. http://dx.doi.org/10.1038/322397a0.

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9

Aitken, Alastair. "Protein Consensus Sequence Motifs." Molecular Biotechnology 12, no. 3 (1999): 241–54. http://dx.doi.org/10.1385/mb:12:3:241.

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10

Nelson, Adin, Ivelise Rijo, Zhigang Zhang, Andrew D. Zelenetz, and Ariela Noy. "Feasiblity and Implication of Bidirectional Sequencing Using a Multiplex Framework 2 Region Primer for Somatic Mutation Analysis of the Immunoglobulin (IgH) Heavy Chain in Chronic Lymphocytic Leukemia (CLL)." Blood 110, no. 11 (2007): 4706. http://dx.doi.org/10.1182/blood.v110.11.4706.4706.

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Abstract Background: A somatic mutation rate of >2% of the immunoglobulin (IgH) heavy chain gene, in comparison to germline DNA, is a positive prognostic indicator in chronic lymphocytic leukemia (CLL). Genomic DNA is amplified using the Biomed-2 multiplex PCR primer set, sequenced in the reverse direction only using a 3′ JH primer, and compared to the germline sequence in VBase, a comprehensive directory of all human germline variable region sequences compiled from over a thousand published sequences. It is unknown whether forward sequencing using the multiplex 5′ Biomed-2 primers in a sin

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Tesis sobre el tema "Consensus sequence"

1

Wilson, Lindsay Anne. "The enterobacterial repeated intergenic consensus (ERIC) sequence." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342441.

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Mokin, Sergey. "Measuring deviation from a deeply conserved consensus in protein multiple sequence alignments." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=21956.

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Proteins across species show variable degrees of conservation. Different patterns of conservation in the columns of an alignment indicate different evolutionary pressures on sequences. Protein conservation analysis is useful for a wide variety of applications, including disease mutation assessment, pseudogene analysis and functional residue prediction. This study describes a novel measure of column conservation in protein multiple sequence alignments (‘MSA'), and the application of this measure to calculate statistical deviation from alignment consensus (‘SDAC'). We have assessed SDAC for two

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3

Kamura, Eri. "Exploring the Methylation Status of RAI1 and the RAI1 Consensus Binding Sequence." VCU Scholars Compass, 2009. http://scholarscompass.vcu.edu/etd/1891.

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Smith Magenis Syndrome (SMS) is a multiple congenital anomalies/ mental retardation disorder caused by deletion or mutation of the RAI1 gene on chromosome 17p11.2. The majority of patients with SMS phenotypes have a deletion or mutation of RAI1. However, some patients have been observed with SMS-like phenotypes and yet have no deletions or mutations in the RAI1 gene. One possible explanation could be aberrant methylation of RAI1 since RAI1 is present and yet may be silenced. In order to study this possibility, patient cell lines were treated with 5-Aza-2’-deoxycytidine. RNA was extracted a

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4

Babst, Scheán. "Mitochondrial DNA consensus sequence for the Tswana population of South Africa / Scheán Babst." Thesis, North-West University, 2012. http://hdl.handle.net/10394/9110.

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Evolutionary studies are critical in eliciting the fundamental phylogeny within and among populations of living organisms. Genetic diversity is displayed in human mitochondrial DNA (mtDNA) as haplogroups that consist of shared mutations, which are carried to the following generation through the maternal lineage. The current haplogroup hierarchies commonly used to describe and compare the genetic diversity of global human populations are based on the available mtDNA sequence variation datasets of numerous continent-specific populations. The description of mtDNA variation in human populations is

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Mouton, Christa. "Mitochondrial genome consensus sequence for the South African Khoi-San population / Christa Mouton." Thesis, North-West University, 2003. http://hdl.handle.net/10394/9618.

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Maternal inheritance and the absence of recombination have contributed to mitochondrial deoxyribonucleic acid (mtDNA) being utilised to study human evolution. This, together with an increased mutation rate in mtDNA, provides information about the most recent common ancestor of modern humans. Previous studies suggested that Africa harbours the highest mtDNA diversity, supporting an out-of-Africa hypothesis for modern human evolution. From subsequent studies it was suggested that the Khoi-San population, in particularly the !Kung, cluster at the deepest root of the global phylogenetic tree. The

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Wynn, Anna. "Four differentially expressed cDNAs containing the Rebers-Riddiford consensus sequence in Callinectes sapidus /." Electronic version (PDF), 2004. http://dl.uncw.edu/etd/2004/wynna/annawynn.pdf.

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Ng, Harald. "Distributed Consensus: Performance Comparison of Paxos and Raft." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-281973.

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With the growth of the internet, distributed systems have become increasingly important in order to provide more available and scalable applications. Con- sensus is a fundamental problem in distributed systems where multiple pro- cesses have to agree on the same proposed value in the presence of partial failures. Distributed consensus allows for building various applications such as lock services, configuration manager services or distributed databases.Two well-known consensus algorithms for building distributed logs are Multi-Paxos and Raft. Multi-Paxos was published almost three decades befo

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8

Wen, Meimei. "Structural studies of a consensus sequence peptide (CSP) ABAB of apolipoproteins through NMR spectroscopy." Thesis, Boston University, 2013. https://hdl.handle.net/2144/11084.

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Thesis (Ph.D.)--Boston University<br>The apolipoproteins play critical roles in lipid transport, lipid metabolism and the pathophysiology of dyslipoproteinemias, most importantly atherosclerosis. ApoA-1 is a representative member of the family of exchangeable apolipoproteins and the major apolipoprotein of high density lipoprotein (HDL). HDL is responsible for the pathway of reverse cholesterol transport and the only particle capable of removing cholesterol from peripheral cells for transport to the liver. The sequences ofthe exchangeable apolipoproteins contain 11/22 residue tandem sequence

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McMillen, Lyle, and l. mcmillen@sct gu edu au. "Isolation and Characterisation of the 5'-Nucleotidase from Escherichia coli." Griffith University. School of Biomolecular and Biomedical Science, 2001. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20030226.153545.

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Escherichia coli 5'-nucleotidase is a periplasmically localised enzyme capable of hydrolysing a broad range of substrates, including all 5'-ribo- and 5'-deoxyribonucleotides, uridine diphosphate sugars, and a number of synthetic substrates such as bis (r-nitrophenyl) phosphate. The enzyme has been shown to contain at least one zinc ion following purification, and to have two metal binding sites in the catalytic cleft. 5'-Nucleotidase activity is significantly stimulated by the addition of particular divalent metal ions, most notably cobalt which results in a 30-50 fold increase in activity.

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McMillen, Lyle. "Isolation and Characterisation of the 5'-Nucleotidase from Escherichia coli." Thesis, Griffith University, 2001. http://hdl.handle.net/10072/366487.

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Escherichia coli 5'-nucleotidase is a periplasmically localised enzyme capable of hydrolysing a broad range of substrates, including all 5'-ribo- and 5'-deoxyribonucleotides, uridine diphosphate sugars, and a number of synthetic substrates such as bis (r-nitrophenyl) phosphate. The enzyme has been shown to contain at least one zinc ion following purification, and to have two metal binding sites in the catalytic cleft. 5'-Nucleotidase activity is significantly stimulated by the addition of particular divalent metal ions, most notably cobalt which results in a 30-50 fold increase in activity.

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Libros sobre el tema "Consensus sequence"

1

Aitken, Alastair. Identification of protein consensus sequences: Active site motifs, phosphorylation, and other post-translational modifications. Ellis Horwood, 1990.

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Aitken, Alastair. Identification of protein consensus sequences: Active site motifs, phosphorylation, and other post-translational modifications. Ellis Horwood, 1990.

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3

Kurt, Bayertz, ed. The Concept of moral consensus: The case of technological interventions in human reproduction. Kluwer Academic Publishers, 1994.

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4

Identification of Protein Consensus Sequences: Active Site Motifs, Phosphorylation, and Other Posttranslational Modifications (Ellis Horwood Books in the Biological Sciences). Ellis Horwood Ltd, 1990.

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5

Lilja, Sven. Climate, History, and Social Change in Sweden and the Baltic Sea Area From About 1700. Oxford University Press, 2017. http://dx.doi.org/10.1093/acrefore/9780190228620.013.633.

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The growing concern about global warming has turned focus in Sweden and other Baltic countries toward the connection between history and climate. Important steps have been taken in the scientific reconstruction of climatic parables. Historic climate data have been published and analyzed, and various proxy data have been used to reconstruct historic climate curves. The results have revealed an ongoing regional warming from the late 17th to the early 21st century. The development was not continuous, however, but went on in a sequence of warmer and colder phases.Within the fields of history and s

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6

Henzi, Bettina, and Maja Steinlin. Stroke in children. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198722366.003.0013.

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Stroke in children is a rare, but terrifying disease and its lifelong sequelae weigh heavy on patients and families. It is also increasingly recognized as a socioeconomic burden, ongoing for many years after the acute manifestation. There is a significant delay in diagnosis of childhood stroke. This is caused by several factors: lack of awareness among the public and professionals, childhood-specific manifestations, numerous stroke mimics, and last but not least, limited access to emergency neuroimaging for children. Fast stroke recognition tools need adaption to the special needs in children.

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Capítulos de libros sobre el tema "Consensus sequence"

1

Ruan, Jianhua. "Consensus Sequence." In Encyclopedia of Systems Biology. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_333.

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Gooch, Jan W. "Consensus Sequence." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_13457.

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Valášek, Leoš Shivaya. "Kozak Consensus Sequence." In Encyclopedia of Systems Biology. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_1265.

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Aitken, Alastair. "Protein Consensus Sequence Motifs." In Protein Sequencing Protocols. Humana Press, 2003. http://dx.doi.org/10.1385/1-59259-342-9:465.

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Piech, Henryk. "Sequence Automata for Researching Consensus Levels." In Lecture Notes in Computer Science. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-34645-3_4.

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Piech, Henryk. "Sequence Automata for Researching Consensus Levels." In Agent and Multi-Agent Systems: Technologies and Applications. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-22000-5_27.

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Kociumaka, Tomasz, Jakub W. Pachocki, Jakub Radoszewski, Wojciech Rytter, and Tomasz Waleń. "On the String Consensus Problem and the Manhattan Sequence Consensus Problem." In String Processing and Information Retrieval. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-11918-2_24.

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Kashkoush, Mohamed, and Hoda A. ElMaraghy. "Generating Master Assembly Sequence Using Consensus Trees." In Enabling Manufacturing Competitiveness and Economic Sustainability. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-02054-9_44.

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Shyu, Conrad, and James A. Foster. "Evolving Consensus Sequence for Multiple Sequence Alignment with a Genetic Algorithm." In Genetic and Evolutionary Computation — GECCO 2003. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-45110-2_124.

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Bodlaender, Hans, Rodney G. Downey, Michael R. Fellows, and Harold T. Wareham. "The parameterized complexity of sequence alignment and consensus." In Combinatorial Pattern Matching. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/3-540-58094-8_2.

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Actas de conferencias sobre el tema "Consensus sequence"

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Jie, Penghai, and Jing Zhu. "Optimal Denial-of-Service Attack Sequence towards the Consensus of Multi-Agent Systems." In 2024 4th International Conference on Control Theory and Applications (ICoCTA). IEEE, 2024. https://doi.org/10.1109/icocta64736.2024.00061.

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Bartos, Milan, SaadedineTebbal, Jorge Pacheco, Tracey Jackson, and Nathan Davis. "Surface Preparation of Test Specimens and Its Impact on Localized Corrosion." In CORROSION 2020. NACE International, 2020. https://doi.org/10.5006/c2020-14844.

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Abstract Laboratory qualification of corrosion inhibitors for oilfield applications is a multistage process consisting of a suite of performance and compatibility tests mimicking the field conditions as closely as possible. The final and often decisive step in this sequence is typically a longer-term test focusing on the performance of corrosion inhibitor candidates against localized corrosion. Despite its fundamental importance in the decision-making process, there is currently no consensus in the industry about the definition of localized corrosion and the pass/fail criteria for tested inhib

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Sousa, Maria J. P., Armando J. Pinho, and Diogo Pratas. "Improving the Generation of Viral Consensus Sequences Using Adaptive Models." In 2024 32nd European Signal Processing Conference (EUSIPCO). IEEE, 2024. http://dx.doi.org/10.23919/eusipco63174.2024.10715352.

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Guha, Soumee, Lisa S. Berlizova, Zongli Lin, and Scott T. Acton. "Dynamic Average Consensus for Improving Classifier Accuracy for Multi-Camera Video Sequences." In 2024 58th Asilomar Conference on Signals, Systems, and Computers. IEEE, 2024. https://doi.org/10.1109/ieeeconf60004.2024.10942702.

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Senkowski, E. Bud. "Corrosion: the Destructive Stowaway on Marine Vessels Determining the Cost-Benefit of Protective Marine Coating Systems." In SSPC 2015 Greencoat. SSPC, 2015. https://doi.org/10.5006/s2015-00056.

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Abstract Marine coating systems installed aboard commercial and military vessels are exposed to extremely aggressive environmental conditions during maritime operation. A key element in prolonging the useful life of any ship, both commercial and military, lies in the selection and installation of cost-effective corrosion control methods and materials at newbuild, followed by an effective painting and preservation program to minimize the corrosive effects of operating in a marine environment, extend the service life and maintenance requirements of the installed systems, and thereby reduce the t

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Sahu, Anit Kumar, and Soummya Kar. "Distributed sequence prediction: A consensus+innovations approach." In 2016 IEEE Global Conference on Signal and Information Processing (GlobalSIP). IEEE, 2016. http://dx.doi.org/10.1109/globalsip.2016.7905854.

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Danckaert, A., S. Hazout, and A. J. Valleron. "Automated DNA sequencing and construction of consensus sequence." In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 1988. http://dx.doi.org/10.1109/iembs.1988.94560.

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Al Khatib, Hebah A., Fatiha M. Benslimane, Israa El Bashir, Asmaa A. Al Thani, and Hadi M. Yassine. "Within-Host Diversity of SARS-Cov-2 in COVID-19 Patients with Variable Disease Severities." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0280.

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Background: The ongoing pandemic of SARS-COV-2 has already infected more than eight million people worldwide. The majority of COVID-19 patients are either asymptomatic or have mild symptoms. Yet, about 15% of the cases experience severe complications and require intensive care. Factors determining disease severity are not yet fully characterized. Aim: Here, we investigated the within-host virus diversity in COVID-19 patients with different clinical manifestations. Methods: We compared SARS-COV-2 genetic diversity in 19 mild and 27 severe cases. Viral RNA was extracted from nasopharyngeal sampl

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Cull, P., and J. L. Holloway. "Optimistically building a consensus sequence using F-inexact matches (DNA)." In Proceedings of the Twenty-Fifth Hawaii International Conference on System Sciences. IEEE, 1992. http://dx.doi.org/10.1109/hicss.1992.183217.

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Haghpanahi, Masoumeh, Reza Sameni, and David A. Borkholder. "Scoring consensus of multiple ECG annotators by optimal sequence alignment." In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2014. http://dx.doi.org/10.1109/embc.2014.6943971.

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Informes sobre el tema "Consensus sequence"

1

Montville, Thomas J., and Roni Shapira. Molecular Engineering of Pediocin A to Establish Structure/Function Relationships for Mechanistic Control of Foodborne Pathogens. United States Department of Agriculture, 1993. http://dx.doi.org/10.32747/1993.7568088.bard.

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This project relates the structure of the bacteriocin molecule (which is genetically determined) to its antimicrobial function. We have sequenced the 19,542 bp pediocin plasmid pMD136 and developed a genetic transfer system for pediococci. The pediocin A operon is complex, containing putative structural, immunity, processing, and transport genes. The deduced sequence of the pediocin A molecule contains 44 amino acids and has a predicted PI of 9.45. Mechanistic studies compared the interaction of pediocin PA-1 and nisin with Listeria monocytgenes cells and model lipid systems. While significant

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2

MR MSK Cartilage for Joint Disease, Consensus Profile. Chair Thomas Link and Xiaojuan Li. Radiological Society of North America (RSNA) / Quantitative Imaging Biomarkers Alliance (QIBA), 2021. http://dx.doi.org/10.1148/qiba/20210925.

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The goal of a QIBA Profile is to help achieve a useful level of performance for a given biomarker. The Claim (Section 2) describes the biomarker performance. The Activities (Section 3) contribute to generating the biomarker. Requirements are placed on the Actors that participate in those activities as necessary to achieve the Claim. Assessment Procedures (Section 4) for evaluating specific requirements are defined as needed. This QIBA Profile (MR-based cartilage compositional biomarkers (T1ρ, T2) ) addresses the application of T1ρ and T2 for the quantification of cartilage composition, which c

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Sherman, A., D. N. Kuhn, Y. Cohen, R. Ophir, and R. Goenaga. Exploring the polyembryonic seed trait in mango as a basis for a biotechnology platform for fruit tree crops. United States-Israel Binational Agricultural Research and Development Fund, 2021. http://dx.doi.org/10.32747/2021.8134176.bard.

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Mango is one of the most important fruit crops. However, the biology of this fruit tree is under studied. The lack of genetic and genomic resources has limited progress in mango research and breeding. Several research groups have recently started developing genomic tools for mango by creating transcriptome and genomic data. Sexual reproduction in plants is the main pathway for the creation of new genetic combinations. In modern agriculture, breeders exploit the genetic diversity generated through sexual reproduction to develop elite cultivars; however, these cultivars require genetic stabiliza

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Shapira, Roni, Judith Grizzle, Nachman Paster, Mark Pines, and Chamindrani Mendis-Handagama. Novel Approach to Mycotoxin Detoxification in Farm Animals Using Probiotics Added to Feed Stuffs. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7592115.bard.

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T-2 toxin, a toxic product belongs to the trichothecene mycotoxins, attracts major interest because of its severe detrimental effects on the health of human and farm animals. The occurrence of trichothecenes contamination is global and they are very resistant to physical or chemical detoxification techniques. Trichothecenes are absorbed in the small intestine into the blood stream. The hypothesis of this project was to develop a protecting system using probiotic bacteria that will express trichothecene 3-O-acetyltransferase (Tri101) that convert T-2 to a less toxic intermediate to reduce inges

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Zhou, Ting, Roni Shapira, Peter Pauls, Nachman Paster, and Mark Pines. Biological Detoxification of the Mycotoxin Deoxynivalenol (DON) to Improve Safety of Animal Feed and Food. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7613885.bard.

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The trichothecene deoxynivalenol (DON, vomitoxin), one of the most common mycotoxin contaminants of grains, is produced by members of the Fusarium genus. DON poses a health risk to consumers and impairs livestock performance because it causes feed refusal, nausea, vomiting, diarrhea, hemolytic effects and cellular injury. The occurrence of trichothecenes contamination is global and they are very resistant to physical or chemical detoxification techniques. Trichothecenes are absorbed in the small intestine into the blood stream. The overall objective of this project was to develop a protecting

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Walker, Michael, Gill Holcombe, Clare Mills, Chiara Nitride, and Adrian Rogers. Development of Reference Materials for food allergen analysis. Food Standards Agency, 2023. http://dx.doi.org/10.46756/sci.fsa.hwt621.

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Food hypersensitivity is an increasing problem for many stakeholders with much effort focused on assessment and management of the risks including risk assessment toolkits (for example, the Allergen Bureau (Opens in a new window) Voluntary Incidental Trace Allergen Labelling VITAL®, the iFAAM consortium (Opens in a new window) and the ILSI-Europe Allergen Quantitative Risk Assessment guidance (Opens in a new window)). These toolkits describe the use of action levels and reference doses to assess the risks. A combination of the estimated eliciting dose of allergenic food, (in milligrams as prote

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Severe Cutaneous Adverse Reactions. A consensus by a CIOMS Working Group. CIOMS, 2025. https://doi.org/10.56759/lrty1600.

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In clinical practice, there is mounting concern about the burden of SCAR in relation to novel biologics as well as the increasing cost of diagnosis and management. This consensus report provides unique insights and the latest thinking from renowned experts on this important topic. The skin is among the parts of the body most commonly affected by adverse drug reactions (ADRs). Cutaneous ADRs affect 2% to 3% of all hospitalized patients and have a wide spectrum of clinical manifestations, are caused by various medicinal products, and result from different pathophysiologic mechanisms. Hence, thei

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