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Literatura académica sobre el tema "Cholera"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 31 de julio de 2024

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Artículos de revistas sobre el tema "Cholera"

Ryan, Edward T., Daniel T. Leung, Owen Jensen, Ana A. Weil, Taufiqur Rahman Bhuiyan, Ashraful Islam Khan, Fahima Chowdhury et al. "Systemic, Mucosal, and Memory Immune Responses following Cholera". Tropical Medicine and Infectious Disease 6, n.º 4 (27 de octubre de 2021): 192. http://dx.doi.org/10.3390/tropicalmed6040192.

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Vibrio cholerae O1, the major causative agent of cholera, remains a significant public health threat. Although there are available vaccines for cholera, the protection provided by killed whole-cell cholera vaccines in young children is poor. An obstacle to the development of improved cholera vaccines is the need for a better understanding of the primary mechanisms of cholera immunity and identification of improved correlates of protection. Considerable progress has been made over the last decade in understanding the adaptive and innate immune responses to cholera disease as well as V. cholerae infection. This review will assess what is currently known about the systemic, mucosal, memory, and innate immune responses to clinical cholera, as well as recent advances in our understanding of the mechanisms and correlates of protection against V. cholerae O1 infection.

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Daniszewski, Piotr. "Vibrio cholerae - As Biological Weapons". International Letters of Social and Humanistic Sciences 9 (septiembre de 2013): 65–73. http://dx.doi.org/10.18052/www.scipress.com/ilshs.9.65.

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Terrorism is defined as use of unlawful violence or threat of unlawful violence to indulge fear; intended to coerce or to intimidate governments or societies in the pursuit of goals that are generally political, social or religious. Bioterrorism is terrorism by intentional release or dissemination of biological agents, mainly bacteria or viruses. Use of biological weapons is attractive from the terrorists’ point of view because of low production costs, major range and easiness of transmission. The first mention of the use of primitive biological weapons date back to the 6th century. Use of plague-infested corpses as offensive means in the 14th century caused a spread of bubonic plague through the whole Europe. The biggest development of biological weapons took place in the interwar period and in the cold war era. Biological weapon trails and research were conducted by super powers such as USSR, UK, USA and Japan. At the beginning of the 20th century a new form of bioterrorism occurred, which put humanity in the face of a terrifying threat. Cholera is a deadly disease that has caused a worldwide phenomenon throughout history. Its imperative weapon, the Vibrio cholerae bacterium, has allowed cholera to seize control and wipe out a huge percentage of the human population. V. cholerae’s toxins are the primary causes of cholera’s lethal symptoms. The bacterium contains toxins that help it accomplish its job of invading the human system and defeating the body’s powerful immune system. With its sibling bacterium Escherichia coli, V. cholerae has become one of the most dominant pathogens in the known world. V. cholerae’s strategies in causing the infamous deadly diarrhea have been widely studied, from the irritation of the intestinal epithelium to the stimulation of capillary leakage, as well as the internal effects of the disease such as the Peyer’s patches on the intestinal walls. Overall, the Vibrio cholera bacterium has made cholera a tough disease to overcome, and because of its deadly virulence factors, cholera has become one of the most frightening diseases a human body could ever encounter. Vibrio cholerae is a Gram-negative, comma-shaped bacterium. Some strains of V. cholerae cause the disease cholera. V. cholerae is facultatively anaerobic and has a flagellum at one cell pole. V. cholerae was first isolated as the cause of cholera by Italian anatomist Filippo Pacini in 1854, but his discovery was not widely known until Robert Koch, working independently 30 years later, publicized the knowledge and the means of fighting the disease. V. cholerae pathogenicity genes code for proteins directly or indirectly involved in the virulence of the bacteria. During infection, V. cholerae secretes cholera toxin, a protein that causes profuse, watery diarrhea. Colonization of the small intestine also requires the toxin coregulated pilus (TCP), a thin, flexible, filamentous appendage on the surface of bacterial cells.

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Kaper, J. B., J. G. Morris y M. M. Levine. "Cholera." Clinical Microbiology Reviews 8, n.º 1 (enero de 1995): 48–86. http://dx.doi.org/10.1128/cmr.8.1.48.

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Despite more than a century of study, cholera still presents challenges and surprises to us. Throughout most of the 20th century, cholera was caused by Vibrio cholerae of the O1 serogroup and the disease was largely confined to Asia and Africa. However, the last decade of the 20th century has witnessed two major developments in the history of this disease. In 1991, a massive outbreak of cholera started in South America, the one continent previously untouched by cholera in this century. In 1992, an apparently new pandemic caused by a previously unknown serogroup of V. cholerae (O139) began in India and Bangladesh. The O139 epidemic has been occurring in populations assumed to be largely immune to V. cholerae O1 and has rapidly spread to many countries including the United States. In this review, we discuss all aspects of cholera, including the clinical microbiology, epidemiology, pathogenesis, and clinical features of the disease. Special attention will be paid to the extraordinary advances that have been made in recent years in unravelling the molecular pathogenesis of this infection and in the development of new generations of vaccines to prevent it.

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LaRocque, Regina C., Bryan Krastins, Jason B. Harris, Lauren M. Lebrun, Kenneth C. Parker, Michael Chase, Edward T. Ryan, Firdausi Qadri, David Sarracino y Stephen B. Calderwood. "Proteomic Analysis of Vibrio cholerae in Human Stool". Infection and Immunity 76, n.º 9 (30 de junio de 2008): 4145–51. http://dx.doi.org/10.1128/iai.00585-08.

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ABSTRACT An effective vaccine for Vibrio cholerae is not yet available for use in the developing world, where the burden of cholera disease is highest. Characterizing the proteins that are expressed by V. cholerae in the human host environment may provide insight into the pathogenesis of cholera and assist with the development of an improved vaccine. We analyzed the V. cholerae proteins present in the stools of 32 patients with clinical cholera. The V. cholerae outer membrane porin, OmpU, was identified in all of the human stool samples, and many V. cholerae proteins were repeatedly identified in separate patient samples. The majority of V. cholerae proteins identified in human stool are involved in protein synthesis and energy metabolism. A number of proteins involved in the pathogenesis of cholera, including the A and B subunits of cholera toxin and the toxin-coregulated pilus, were identified in human stool. In a subset of stool specimens, we also assessed which in vivo expressed V. cholerae proteins were recognized uniquely by convalescent-phase as opposed to acute-phase serum from cholera patients. We identified a number of these in vivo expressed proteins as immunogenic during human infection. To our knowledge, this is the first characterization of the proteome of a pathogenic bacteria recovered from a natural host.

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Tyurina, A. V., N. E. Gaevskaya, I. A. Ivanova, A. V. Filippenko, N. D. Omel’chenko, A. A. Trufanova, M. P. Pogozhova, A. O. Anoprienko, Yu V. Sizova y N. I. Pasyukova. "Assessment of the Effectiveness of Cholera Bacteriophages for Prevention of Experimental Cholera". Problems of Particularly Dangerous Infections, n.º 2 (3 de julio de 2024): 193–95. http://dx.doi.org/10.21055/0370-1069-2024-2-193-195.

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The possibility of cholera importation into our country and the increase in the number of Vibrio cholerae strains that are resistant to antibacterial agents necessitate the development of alternative therapeutic and prophylactic biological products based on bacteriophages.The aim of the work was to study the effectiveness of application of cholera bacteriophages for the prevention of experimental cholera.Materials and methods. The work involved cholera bacteriophages Rostov-M3, Rostov-13, active against cholera vibrios of the O1 serogroup; and FB1, which has lytic activity against the O139 serogroup. The effectiveness of cholera prevention was assessed using a model of an isolated loop of the small intestine in an adult rabbit.Results and discussion. The use of Rostov-M3 and Rostov-13 for five and especially seven days before infection with virulent strains of V. cholerae O1 serogroup prevents the development of infection in the small intestine of experimental animals. Bacteriophage FB1 did not have that ability against V. cholerae O139. These studies indicate the effectiveness of using phages Rostov-M3 and Rostov-13 for the prevention of experimental cholera caused by V. cholerae O1 serogroup.

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Maurice Bilung, Lesley, Mintra Prommani Etriam, Ahmad Syatir Tahar, Teng Sing Tung y Kasing Apun. "Detection of Cholera Toxin-Producing Vibrio cholerae in Phytoplankton from Santubong and Samariang Estuaries". Borneo Journal of Resource Science and Technology 9, n.º 1 (30 de junio de 2019): 36–43. http://dx.doi.org/10.33736/bjrst.1584.2019.

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Many cholera outbreaks worldwide were associated with cholera toxin-producing Vibrio cholerae. The bacteria are ubiquitous in aquatic environment, whilst phytoplankton is associated with adaptation of the Vibrio species. This study was conducted to detect cholera toxin-producing Vibrio cholerae, and to determine association of the selected water physicochemical parameters with the number of the bacteria. In this study, a total of ten phytoplankton samples were collected at Santubong and Samariang Estuaries in Kuching, Sarawak. Water physicochemical parameters (temperature, pH and salinity) were recorded. Vibrio bacteria were cultivated on thiosulfate citrate bile-salts sucrose selective agar and analysed for cholera toxin-producing Vibrio cholerae using polymerase chain reaction by targeting ctxA gene that encodes for virulence cholera enterotoxin subunit A. The result revealed that a range of 1.0 × 107 – 8.0 × 107 CFU/ml of yellow colonies growing on the thiosulfate citrate bile-salts sucrose agars. Inversely, no samples were positive with cholera toxin-producing Vibrio cholerae. The physicochemical parameters at Samariang Estuary were more associated with the number of bacteria in the samples compared to Santubong Estuary.

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Nasreen, Tania, Nora A. S. Hussain, Mohammad Tarequl Islam, Fabini D. Orata, Paul C. Kirchberger, Rebecca J. Case, Munirul Alam, Stephanie K. Yanow y Yann F. Boucher. "Simultaneous Quantification of Vibrio metoecus and Vibrio cholerae with Its O1 Serogroup and Toxigenic Subpopulations in Environmental Reservoirs". Pathogens 9, n.º 12 (16 de diciembre de 2020): 1053. http://dx.doi.org/10.3390/pathogens9121053.

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Vibrio metoecus is a recently described aquatic bacterium and opportunistic pathogen, closely related to and often coexisting with Vibrio cholerae. To study the relative abundance and population dynamics of both species in aquatic environments of cholera-endemic and cholera-free regions, we developed a multiplex qPCR assay allowing simultaneous quantification of total V. metoecus and V. cholerae (including toxigenic and O1 serogroup) cells. The presence of V. metoecus was restricted to samples from regions that are not endemic for cholera, where it was found at 20% of the abundance of V. cholerae. In this environment, non-toxigenic O1 serogroup V. cholerae represents almost one-fifth of the total V. cholerae population. In contrast, toxigenic O1 serogroup V. cholerae was also present in low abundance on the coast of cholera-endemic regions, but sustained in relatively high proportions throughout the year in inland waters. The majority of cells from both Vibrio species were recovered from particles rather than free-living, indicating a potential preference for attached versus planktonic lifestyles. This research further elucidates the population dynamics underpinning V. cholerae and its closest relative in cholera-endemic and non-endemic regions through culture-independent quantification from environmental samples.

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Yadav, Sachin. "A Case Report Cholera Outbreak in Gaidataar: A Lesson for Further Strengthening the Task Force for Epidemic Management in Nepal". Journal of Nepal Medical Association 56, n.º 207 (30 de septiembre de 2017): 374–76. http://dx.doi.org/10.31729/jnma.3284.

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Cholera is an acute enteric infection caused by the ingestion of bacterium Vibrio cholerae1. Cholera is transmitted through contaminated food and water. Prevention and preparedness of cholera require a coordinated multi-disciplinary approach. The extremely short incubation period enhances the potentially explosive pattern of outbreaks. Cholera can lead to severe dehydration and death if left untreated. The laboratory testing is required for antimicrobial sensitivity testing and for confirming the end of an outbreak. Provision of safe drinking water, proper sanitation, and food safety are critical for preventing occurrence of cholera. Health education aims at communities adopting preventive behavior for averting contamination. Specific training for all the staffs about proper case management including avoidance of noso-comial infection (like face masks, gloves, antiseptic solution, hand scrubs). Sufficient pre-positioned medical supplies for case management (diarrhoeal disease kits, iv fluids, antibiotics, safety measures). Improved access to water, effective sanitation, proper waste management and vector control. Improved communication and public information. Oral Rehydration Salts can treat 80% of cholera1. Appropriate antibiotics can reduce the duration of purging. With a well and properly managed team of health experts with all essential medicines and a good rapid response team, any outbreak can be prevented, controlled and managed. Keywords: cholera; epidemic; ORS; rapid response team; shanchol; task force.

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Alam, Munirul, Marzia Sultana, G. Balakrish Nair, R. Bradley Sack, David A. Sack, A. K. Siddique, Afsar Ali, Anwar Huq y Rita R. Colwell. "Toxigenic Vibrio cholerae in the Aquatic Environment of Mathbaria, Bangladesh". Applied and Environmental Microbiology 72, n.º 4 (abril de 2006): 2849–55. http://dx.doi.org/10.1128/aem.72.4.2849-2855.2006.

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ABSTRACT Toxigenic Vibrio cholerae, rarely isolated from the aquatic environment between cholera epidemics, can be detected in what is now understood to be a dormant stage, i.e., viable but nonculturable when standard bacteriological methods are used. In the research reported here, biofilms have proved to be a source of culturable V. cholerae, even in nonepidemic periods. Biweekly environmental surveillance for V. cholerae was carried out in Mathbaria, an area of cholera endemicity adjacent to the Bay of Bengal, with the focus on V. cholerae O1 and O139 Bengal. A total of 297 samples of water, phytoplankton, and zooplankton were collected between March and December 2004, yielding eight V. cholerae O1 and four O139 Bengal isolates. A combination of culture methods, multiplex-PCR, and direct fluorescent antibody (DFA) counting revealed the Mathbaria aquatic environment to be a reservoir for V. cholerae O1 and O139 Bengal. DFA results showed significant clumping of the bacteria during the interepidemic period for cholera, and the fluorescent micrographs revealed large numbers of V. cholerae O1 in thin films of exopolysaccharides (biofilm). A similar clumping of V. cholerae O1 was also observed in samples collected from Matlab, Bangladesh, where cholera also is endemic. Thus, the results of the study provided in situ evidence for V. cholerae O1 and O139 in the aquatic environment, predominantly as viable but nonculturable cells and culturable cells in biofilm consortia. The biofilm community is concluded to be an additional reservoir of cholera bacteria in the aquatic environment between seasonal epidemics of cholera in Bangladesh.

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Moskvitina, E. A., E. G. Yanovich, M. I. Kurilenko, V. D. Kruglikov, S. V. Titova, D. A. Levchenko, A. S. Vodop’yanov et al. "Cholera: Monitoring of Epidemiological Situation around the World and in Russia (2010–2019). Forecast for 2020". Problems of Particularly Dangerous Infections, n.º 2 (12 de julio de 2020): 38–47. http://dx.doi.org/10.21055/0370-1069-2020-2-38-47.

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Objective of the study was to monitor the spread of cholera in the world, in the CIS countries and in Russia with an assessment of risks and emergencies that contribute to the activation of the epidemic process. Despite the downward trend in the global incidence rate of cholera during the period between 2010 and 2019, epidemics and major outbreaks occurred in 96 countries. WHO has reported 2013 imported cases of cholera to countries in Asia, the Americas, including the Caribbean, Europe, and Australia with Oceania; cholera-endemic administrative territories are identified in 24 countries. According to WHO, cholera burden reduction in Asia and Africa is associated with large-scale vaccination. During epidemiological surveillance of cholera, 705 strains of V. cholerae O1 and O139 serogroups were isolated from surface reservoirs in 26 constituent entities of the Russian Federation, including 10 strains of V. cholerae O1 ctxA+tcpA+, 35 strains of V. cholerae O1 ctxA–tcpA+, 655 strains of V. cholerae O1 ctxA–tcpA– , and ﬁve strains of V. cholerae O139 ctxA–tcpA–. Identiﬁcation of strains with unique, previously unknown INDEL genotypes testiﬁes to their imported nature. The forecast for cholera in the world for 2020, given the proven high degree of epidemic process activation at the expense of social and environmental risks caused by emergencies of different origin, the presence of endemic foci, infection import and other risk factors is unfavorable. For Russia, the forecast for cholera will be determined by the presence of external risks created by the ongoing 7-th pandemic, possible importation of infection to constituent entities of the Russian Federation that differ by the types of epidemic manifestations.

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Tesis sobre el tema "Cholera"

Moore, Sandra. "Dynamics of cholera epidemics in Haiti and Africa". Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM5505/document.

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Le cholera est une maladie diarrhéique aiguë due à la consommation d’eau ou d’aliments contaminés par des souches toxigéniques de Vibrio cholerae. Selon le “paradigme du choléra”, la maladie est provoquée par une exposition à un réservoir environnemental de V. cholerae avec des épidémies directement modulées par des facteurs environnementaux. Cependant, comme divers arguments plaident contre ce dogme, nous avons voulu élucider les mécanismes de la dynamique des épidémies de cholera dans trois foyers situés en Haïti, en République Démocratique du Congo (RDC) et en Afrique de l’Ouest. Nous avons associé une analyse temporo-spatiale des épidémies à une étude génétique des isolats de V. cholerae. En Haïti, nous avons cherché à savoir si les épidémies actuelles étaient dues à des souches toxigéniques de V. cholerae O1 durablement implantées dans l’environnement aquatique. En Afrique de l’Ouest, notre étude a révélé qu’Accra, la capitale du Ghana, était le principal foyer de choléra pour l’ensemble des pays d’Afrique de l’Ouest situés à l’Ouest du Nigeria. Le réseau d’eau d’Accra a probablement joué un rôle dans la propagation rapide de V. cholerae vers la majorité des quartiers de la ville. Les épidémies de choléra ont diffusé vers les autres pays sous la forme de vagues épidémiques et plusieurs épidémies ont été liées à la migration de populations à risque comme certains pêcheurs. En conclusion, notre réflexion globale sur les épidémies de choléra dans ces trois foyers distincts nous donne une vision cohérente des mécanismes d’émergence et de diffusion du choléra
Cholera is an acute diarrheal disease caused by consumption of water or food contaminated with toxigenic Vibrio cholerae. According to the "cholera paradigm", the disease is contracted by exposure to environmental reservoirs of V. cholerae, with outbreaks driven directly by climatic factors. However, as recent findings argue against this dogma, we aimed to elucidate the dynamics of cholera outbreaks in three global foci: Haiti, Democratic Republic of the Congo (DRC) and West Africa. We combined spatiotemporal analysis of epidemics with genetic assessment of V. cholerae isolates. In Haiti, we assessed whether outbreak re-emergence during the rainy season was due to toxigenic V. cholerae O1 strains that have settled into the aquatic environment. Instead, we found that the re-emergence of outbreaks was likely due to persisting outbreaks during the dry season that were insufficiently controlled, rather than an environmental reservoir of V. cholerae O1. In West Africa, our study revealed that Accra, Ghana was the hotspot of cholera in the entire region of West Africa, west of Nigeria. The Accra water network likely played a role in rapid diffusion of V. cholerae throughout the city. Cholera outbreaks spread from Accra into other countries in a wave-like fashion. Distinct outbreaks were linked via migration of at-risk populations, such as certain fishermen. In conclusion, our global reflection of cholera epidemics in these three distinct foci provides a coherent vision of the mechanisms of cholera emergence and diffusion

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Nygren, Erik. "A mouse model for direct evaluation of cholera vaccines /". Göteborg : Dept. of Microbiology and immunology, Institute of Biomedicine, The Sahlgrenska Academy at University of Gothenburg, 2009. http://hdl.handle.net/2077/19376.

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Le, Roux Wouter Jacobus. "Population dynamics of Vibrio cholerae in the Vaal Barrage". Pretoria : [s.n.], 2005. http://upetd.up.ac.za/thesis/available/etd-02162007-175110.

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Occhino, Deborah Ann. "Vibrio cholerae iron transport : characterization of two tonB systems and components of a heme transport system /". Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.

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Falklind, Jerkérus Susanna. "Vibrio cholerae O139 : identification, characterization and vaccine strategies /". Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-696-0/.

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Mitchell, Daniel David. "Cholera toxin inhibition and EpsF from its secretion system /". Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/9210.

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Zo, Young-Gun. "Phylogenomic and structural analyses of Vibrio cholerae populations and endemic cholera". College Park, Md. : University of Maryland, 2005. http://hdl.handle.net/1903/3090.

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Thesis (Ph. D.) -- University of Maryland, College Park, 2005.
Thesis research directed by: Marine-Estuarine-Environmental Sciences. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.

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Bougoudogo, Fiabou. "Contribution à l'étude de l'immunité protectrice contre le choléra : rôle des anticorps vibriocides reconnaissant le polysaccharide spécifique du lipopolysaccharide de "Vibrio cholerae" O:1". Paris 11, 1994. http://www.theses.fr/1994PA114831.

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Lee, Jason J. "Neutrophil responses to Vibrio cholerae autoinducer-1 and structural analogues". Thesis, Griffith University, 2021. http://hdl.handle.net/10072/404172.

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Vibrio cholerae is a pathogen responsible for cholera, an infectious disease that usually manifests as severe diarrhea. V. cholerae cells can regulate population-wide gene expression changes in a density-dependent manner, in a process known as quorum sensing (QS). QS involves communication between bacterial cells using secreted signalling molecules. V. cholerae autoinducer-1 (CAI-1) is the dominant signalling molecule in the V. cholerae QS circuit and has roles in regulating biofilm formation/degradation and expression of virulence genes. Interactions between bacterial-produced QS molecules and eukaryotic cells have been documented. This is known as interkingdom or cross-kingdom signalling. CAI-1 has been reported to act as a chemoattractant for the nematode, Caenorhabditis elegans which feeds on V. cholerae cells as a food source. Legionella autoinducer-1 (LAI-1), which is structurally similar to CAI-1, is a signalling molecule produced by Legionella pneumophila. LAI-1 has been reported to impede the migration of Dictyostelium discoideum amoebae and macrophage-like RAW 264.7 cells, and has also been shown to destabilise the cytoskeleton of RAW 264.7 cells. Structural analogues of CAI-1 with more potent activity within the V. cholerae QS circuit have been developed as potential novel therapeutics against cholera. These QS agonists would force the bacterial cells to express high cell density behaviours, impairing colonisation and promoting detachment, therefore reducing pathogenesis. These previous findings led to the hypothesis that CAI-1 and structural analogues may have immunomodulatory effects on host cells during V. cholerae infection, particularly recruited immune cells which may be exposed to CAI-1 during cholera. There are several lines of evidence the neutrophil recruitment is prominent during cholera and that these granular leukocytes play a role in controlling infection. Thus, the key aims of this study were to characterise interactions between CAI-1, as well as structural analogues of CAI-1, and neutrophils. In vitro HL-60 cell culture revealed an upregulation of CD11b expression when cells were differentiated with DMSO in the presence of CAI-1. This increased differentiation marker expression was at the expense of both cell viability and total cell count. Additionally, two 3-acyl pyrrole analogues of CAI-1 also increased CD11b expression greater than CAI-1, when cells were differentiated with DMSO in the presence of either analogue. Again, this resulted in significantly reduced cell viability and total cell count, although at similar levels to CAI-1. HL-60 cells differentiated in the presence of CAI-1 or either analogue were generally more granular than cells differentiated with DMSO alone. The effects of CAI-1 and structural analogues on neutrophil effector functions were assessed, namely chemotaxis and oxidative burst. CAI-1 did not act as a chemoattractant for DMSO-differentiated HL-60 cells, nor did it reduce or enhance migration towards fMLP, a known chemoattractant. Pre-treatment of differentiated HL-60 cells with CAI-1 or one of the 3-acyl pyrrole analogues for 3 h resulted in decreased reactive oxygen species production. However, concomitant reduction in cell viability was observed over 3 h. Preliminary experiments assessed the effect of CAI-1 on primary human neutrophils. Isolated neutrophils appeared larger and less round with CAI-1 treatment. In contrast, CAI-1 treatment of whole blood resulted in apparent reductions in cell size as assessed by flow cytometry. Expression of activation markers (CD11b, CD64, CD66b) on granulocytes in whole blood appeared unaffected by CAI-1. Overall, the results within this study shed light onto the cross-kingdom interactions that may exist between host cells and bacterial signalling molecules. Identifying these interactions may lead to a deeper understanding of additional mechanisms that may be involved in V. cholerae pathogenesis. Additionally, these interactions may be important in revealing off-target effects that developing novel therapies, which interfere with bacterial QS, may have on host cells. These data highlight an advance that reveals many opportunities for further investigations surrounding host-microbe interactions.
Thesis (Masters)
Master of Medical Research (MMedRes)
School of Medical Science
Griffith Health
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Salmon, François. "Le choléra au Pérou : leçon pour un continent à risque". Paris 5, 1994. http://www.theses.fr/1994PA05P013.

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Libros sobre el tema "Cholera"

Kaye Wachsmuth, I., Paul A. Blake y Ørjan Olsvik, eds. Vibrio cholerae and Cholera. Washington, DC, USA: ASM Press, 1994. http://dx.doi.org/10.1128/9781555818364.

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1935-, Takeda Yoshifumi, ed. Vibrio cholerae and cholera. Tokyo: KTK Scientific Publishers, 1988.

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Taché, Joseph-Charles. Memorandum on cholera. [Montréal?]: Printed for the Bureau of Agriculture and Statistics, 1992.

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Dr, Ferguson, ed. Memorandum on cholera as to its origin, organism, causes and prevention, with premonitory symptoms. Ottawa: Printed by order of the Minister of Agriculture, 1985.

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William, Stevens. A treatise on cholera. [Kingston, Ont.?: s.n.], 1987.

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Roome y Roome. Mémoire sur le choléra pour ce qui a trait à son origine, organisme, ses causes, moyens de s'en préserver et ses symptômes précurseurs. Ottawa: Imprimé par ordre du Ministre de l'agriculture, 1993.

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William, Coleman. Cholera. Editado por Babcock Hilary. Philadelphia: Chelsea House Publications, 2009.

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Barua, Dhiman y William B. Greenough, eds. Cholera. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4757-9688-9.

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William, Coleman. Cholera. Editado por Alcamo I. Edward. Philadelphia: Chelsea House Pub., 2003.

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Bailey, Diane. Cholera. New York: Rosen Pub., 2011.

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Capítulos de libros sobre el tema "Cholera"

Vugia, Duc J. "Cholera Surveillance". En Vibrio cholerae and Cholera, 371–78. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818364.ch24.

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Wachsmuth, Kaye, Ørjan Olsvik, Gracia M. Evins y Tanja Popovic. "Molecular Epidemiology of Cholera". En Vibrio cholerae and Cholera, 357–70. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818364.ch23.

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Levine, Myron M. y Carol O. Tacket. "Recombinant Live Cholera Vaccines". En Vibrio cholerae and Cholera, 395–413. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818364.ch26.

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Holmgren, J., J. Osek y A. M. Svennerholm. "Protective Oral Cholera Vaccine Based on a Combination of Cholera Toxin B Subunit and Inactivated Cholera Vibrios". En Vibrio cholerae and Cholera, 415–24. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818364.ch27.

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Kay, Bradford A., Cheryl A. Bopp y Joy G. Wells. "Isolation and Identification of Vibrio cholerae O1 from Fecal Specimens". En Vibrio cholerae and Cholera, 1–25. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818364.ch1.

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Barrett, Timothy J. y John C. Feeley. "Serologic Diagnosis of Vibrio cholerae O1 Infections". En Vibrio cholerae and Cholera, 135–41. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818364.ch10.

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Kaper, James B., Alessio Fasano y Michele Trucksis. "Toxins of Vibrio cholerae". En Vibrio cholerae and Cholera, 143–76. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818364.ch11.

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Ottemann, Karen M. y John J. Mekalanos. "Regulation of Cholera Toxin Expression". En Vibrio cholerae and Cholera, 177–85. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818364.ch12.

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Kaufman, Melissa R. y Ronald K. Taylor. "The Toxin-Coregulated Pilus: Biogenesis and Function". En Vibrio cholerae and Cholera, 187–202. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818364.ch13.

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Richardson, Stephen H. "Animal Models in Cholera Research". En Vibrio cholerae and Cholera, 203–26. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818364.ch14.

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Actas de conferencias sobre el tema "Cholera"

Ngoc Anh, Le Thi, Hoang Xuan Dau y Nguyen Hoang Phuong. "Cholera forecast based on mining association rules". En 2015 International Conference on Communications, Management and Telecommunications (ComManTel). IEEE, 2015. http://dx.doi.org/10.1109/commantel.2015.7394274.

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Hameed, Alaa K., Hasan Raheem Khudhur, Noor Ali Mahdi, Mohenned A. Alsaadawi y Ahmed Shayaa Kareem. "Study of cholera in Al-Muthanna province". En PROCEEDING OF THE 1ST INTERNATIONAL CONFERENCE ON ADVANCED RESEARCH IN PURE AND APPLIED SCIENCE (ICARPAS2021): Third Annual Conference of Al-Muthanna University/College of Science. AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0095320.

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Hameed, Hameed Husam, Hayder M. Al-Saedi y Mohammed H. Al-Mayyah. "Mathematical Modelling for Cholera Epidemic in Iraq". En 2023 5th International Conference on Problems of Cybernetics and Informatics (PCI). IEEE, 2023. http://dx.doi.org/10.1109/pci60110.2023.10325918.

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Jayade, Swati, D. T. Ingole, Manik D. Ingole y Aditya Tohare. "Cholera Disease Detection using Fuzzy Logic Technique". En 2021 3rd International Conference on Electrical, Control and Instrumentation Engineering (ICECIE). IEEE, 2021. http://dx.doi.org/10.1109/icecie52348.2021.9664703.

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Garcia Naranjo, A., K. Chamman, AY Gandi, I. Baba Aminu, IM Maigari, R. Mohammed, I. Salisu Idris et al. "Risk factors for mortality among patients with suspected cholera treated in MSF-supported cholera treatment facilities in Bauchi State, Nigeria". En MSF Scientific Day International 2023. NYC: MSF-USA, 2023. http://dx.doi.org/10.57740/hg6x-mj63.

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Cinaroglu, Selim, Ilke Anac, Fatma Nese Kok y Tugba Arzu Ozal Ildeniz. "Molecular Modelling in Biosensor Desgin for Cholera Toxin Detection". En 2017 21st National Biomedical Engineering Meeting (BIYOMUT). IEEE, 2017. http://dx.doi.org/10.1109/biyomut.2017.8479014.

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Xu, Min, Chunxiang Cao y Sheng Zheng. "The use of environmental variables to predict cholera hazard". En IGARSS 2013 - 2013 IEEE International Geoscience and Remote Sensing Symposium. IEEE, 2013. http://dx.doi.org/10.1109/igarss.2013.6721083.

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Zhao, Peiqing. "Cholera Epidemic Prevention in Ningbo in 1930s and 1940s". En 7th International Conference on Humanities and Social Science Research (ICHSSR 2021). Paris, France: Atlantis Press, 2021. http://dx.doi.org/10.2991/assehr.k.210519.236.

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Lotsmanova, Ekaterina Y., Alexander L. Kravtsov, Ludmila F. Livanova, Irina M. Kobkova, Oleg S. Kuznetsov, Tatyana N. Shchukovskaya, Nina I. Smirnova y Vladimir V. Kutyrev. "Flow cytofluorometric monitoring of leukocyte apoptosis in experimental cholera". En SPIE Proceedings, editado por Valery V. Tuchin. SPIE, 2003. http://dx.doi.org/10.1117/12.518875.

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Bozdogan, Anil, Sebnem Seherler, Tugba Arzu Ozal Ildeniz, Ilke Anac y Fatma Nese Kok. "Surface Plasmon Florescence Spectroscopy Based Biosensor for Cholera Toxin Detection". En 2017 21st National Biomedical Engineering Meeting (BIYOMUT). IEEE, 2017. http://dx.doi.org/10.1109/biyomut.2017.8479292.

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Informes sobre el tema "Cholera"

Yeates, Elissa, Kayla Cotterman y Angela Rhodes. Hydrologic impacts on human health : El Niño Southern Oscillation and cholera. Engineer Research and Development Center (U.S.), enero de 2020. http://dx.doi.org/10.21079/11681/39483.

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A non-stationary climate imposes considerable challenges regarding potential public health concerns. The El Niño Southern Oscillation (ENSO) cycle, which occurs every 2 to 7 years, correlates positively with occurrences of the waterborne disease cholera. The warm sea surface temperatures and extreme weather associated with ENSO create optimal conditions for breeding the Vibrio cholerae pathogen and for human exposure to the pathogenic waters. This work explored the impacts of ENSO on cholera occurrence rates over the past 50 years by examining annual rates of suspected cholera cases per country in relation to ENSO Index values. This study provides a relationship indicating when hydrologic conditions are optimal for cholera growth, and presents a statistical approach to answer three questions: Are cholera outbreaks more likely to occur in an El Niño year? What other factors impact cholera outbreaks? How will the future climate impact cholera incidence rates as it relates to conditions found in ENSO? Cholera outbreaks from the 1960s to the present are examined focusing on regions of Central and South America, and southern Asia. By examining the predictive relationship between climate variability and cholera, we can draw conclusions about future vulnerability to cholera and other waterborne pathogenic diseases.

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Alles, Larissa. Yemen: Catastrophic cholera crisis. Oxfam, agosto de 2017. http://dx.doi.org/10.21201/2017.0360.

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Niederberger, Eva y Ginger Johnson. Cholera Questions Bank: Quantitative Questions for Community Level Data Collection. Institute of Development Studies, agosto de 2023. http://dx.doi.org/10.19088/sshap.2023.023.

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This questions bank resource is a menu of quantitative questions related to socio-behavioural factors and Cholera. This resource seeks to facilitate the collection of quality data on community’s capacity, behaviours, practices and perceptions in relation to cholera prevention and management. It can be used by field teams and / or local research teams working in communities with cholera transmission and those at risk adhering to safety and protection protocols. Gathering and using high quality data on social, behavioural and community dynamics in relation to cholera prevention and management is vital to: 1. Understand people’s ability, capacity and behaviour in relation to prevent and/or reduce cholera infection risks. 2. Support evidence-based decision-making on communication and engagement strategies that address people’s needs and priorities in an evolving context. 3. Provide data that decision-makers can use to adapt cholera response and preparedness strategies and activities. 4. Support public health promoters and outreach workers in engaging with local populations to strengthen community-led actions. 5. Enhance the knowledge of public health promoters and outreach workers and support them in clearly communicating on cholera prevention and control. 6. Inform the design and adaptation of information content / messages shared and discussed with the local population.

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Niederberger, Eva y Ginger Johnson. Cholera Questions Bank: Quantitative Questions for Community Level Data Collection. Institute of Development Studies, marzo de 2023. http://dx.doi.org/10.19088/sshap.2023.004.

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Niederberger, Eva y Ginger Johnson. Cholera Questions Bank: Qualitative Questions for Community-Level Data Collection. Institute of Development Studies, julio de 2023. http://dx.doi.org/10.19088/sshap.2023.005.

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This resource is a menu of qualitative questions related to socio-behavioural factors and cholera. It seeks to facilitate the collection of quality data on community’s capacity, behaviours, practices and perceptions in relation to cholera prevention and management. It can be used by field teams and / or local research teams working in communities with cholera transmission and those at risk adhering to safety and protection protocols

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Velsko, S. When did the Haiti cholera outbreak begin? Office of Scientific and Technical Information (OSTI), julio de 2014. http://dx.doi.org/10.2172/1150725.

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Niederberger, Eva y Ginger Johnson. Cholera Questions Bank: Qualitative Questions for Responders. Institute of Development Studies, marzo de 2023. http://dx.doi.org/10.19088/sshap.2023.006.

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This resource provides a set of key questions for responders and social scientists to use when collecting data in the context of a cholera outbreak. It also provides guidance on how to approach gaining a better contextual understanding including relevant socio-behavioural factors influencing community’s capacities, perceptions, knowledge and practices in relation to cholera control and preparedness. Using this resource will support responders and social scientists to identify critical areas for primary data collection either using rapid assessments, household level and community level surveys or more in-depth research.

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Zhang, Rong-Guang, M. L. Westbrook, S. Nance, B. D. Spangler, D. L. Scott y E. M. Westbrook. The three-dimensional crystal structure of cholera toxin. Office of Scientific and Technical Information (OSTI), febrero de 1996. http://dx.doi.org/10.2172/205782.

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Bastian, Elizabeth, Claire Munaretto, Natalie Myers, Carey Baxter, Jamie Fishman, James Westervelt, Charles Ehlschlaeger y Jeffrey Burkhalter. Development of a cholera epidemiological risk assessment framework. Engineer Research and Development Center (U.S.), septiembre de 2019. http://dx.doi.org/10.21079/11681/34162.

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Carruth, Lauren. Key Considerations: Social, Structural and Community Dynamics of Cholera Transmission and Mortality in Ethiopia. Institute of Development Studies, abril de 2024. http://dx.doi.org/10.19088/sshap.2024.004.

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The current cholera outbreak in the Federal Democratic Republic of Ethiopia began in August 2022. As of April 2024, active outbreaks had been recorded in most regions of the country, including: Amhara; Dire Dawa; Harari; Oromia; Southern Nations, Nationalities and Peoples’ Region (SNNPR); Somali and Tigray. This brief has been developed to support response efforts by exploring the social and structural determinants and community dynamics of cholera infection and mortality in Ethiopia. Socio-cultural and epidemiological information, academic and grey literature and consultations with cholera response experts in Ethiopia have been used to develop the brief.

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