Literatura académica sobre el tema "Cellules dendritiques immatures et matures"
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Artículos de revistas sobre el tema "Cellules dendritiques immatures et matures"
Simoneau-Robin, Isabelle, Christiane Mousson, John Wijdenes y Gérard Rifle. "Diminution de la réponse alloréactive in vitro et in vivo par association de cellules dendritiques matures du donneur et d’un anticorps monoclonal anti-CD4 chez le Rat". Journal de la Société de Biologie 195, n.º 4 (2001): 431–35. http://dx.doi.org/10.1051/jbio/2001195040431.
Texto completoGouzé, Jean-Luc y Valérie Lemesle. "Two simple growth models in the chemostat". Revue Africaine de la Recherche en Informatique et Mathématiques Appliquées Volume 9, 2007 Conference in... (2 de septiembre de 2008). http://dx.doi.org/10.46298/arima.1895.
Texto completoTesis sobre el tema "Cellules dendritiques immatures et matures"
Robin, Isabelle. "Etude in vitro et in vivo de l'alloréactivité et du microchimérisme après injection de cellules dendritiques matures et d'un anticorps monoclonal anti-cd4 chez le rat". Dijon, 2003. http://www.theses.fr/2003DIJOMU07.
Texto completoMansuet-Lupo, Audrey. "Influence des caractéristiques morphologiques et mutationnelles des carcinomes pulmonaires sur leur environnement immunitaire et leur pronostic". Electronic Thesis or Diss., Paris 5, 2014. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=647&f=1599.
Texto completoThe major role of the immune system against tumor development is now clearly established, including lung carcinoma. Nevertheless, interaction between tumoral cells and immune environment is less well-defined. In that study, we have studied morphological and molecular tumoral cells characteristics from lung adenocarcinoma and their role in the composition of immune environment. We reported the prognostic value of morphological parameters, as histological grade of adenocarcinoma, and their association with molecular EGFR and KRAS status. We hypothesized that morphological and molecular diversity of these tumors could be associated with a specific intratumoral immune signature, and could have an impact in prognosis. We showed that mature dendritic cells density, located in tertiary lymphoid structures, differed according to EGFR and KRAS status. Morever, molecular status of tumors modified the pronostic value of mature dendritics cells and CD8+ T cells. We found a prognostic value of immune environment, represented by dendritic cells and T CD8+ cells, in operated stage III-N2 lung carcinomas treated by neoadjuvant chemotherapy. At last, we demonstrated that chemotherapy is not associated with wide modifications in immune infiltrate, whereas it induced modifications in tumoral cells. All together, these data strongly argue for a close link between tumoral cells and immune environment, which seems to depend on tumoral cell characteristics. This interaction between tumoral cells and immune cells contribute to the prognosis of these tumors. These results show the evidence that combine cytotoxic treatment, like conventional chemotherapy, with immunomodulators, favour a protective anti-tumor immune response
Flandre, Frédéric. "Mise au point d'un système de régénération du pois (Pisum sativum L. ) par embryogenèse somatique". Amiens, 1994. http://www.theses.fr/1994AMIES013.
Texto completoMansuet-Lupo, Audrey. "Influence des caractéristiques morphologiques et mutationnelles des carcinomes pulmonaires sur leur environnement immunitaire et leur pronostic". Thesis, Paris 5, 2014. http://www.theses.fr/2014PA05T017/document.
Texto completoThe major role of the immune system against tumor development is now clearly established, including lung carcinoma. Nevertheless, interaction between tumoral cells and immune environment is less well-defined. In that study, we have studied morphological and molecular tumoral cells characteristics from lung adenocarcinoma and their role in the composition of immune environment. We reported the prognostic value of morphological parameters, as histological grade of adenocarcinoma, and their association with molecular EGFR and KRAS status. We hypothesized that morphological and molecular diversity of these tumors could be associated with a specific intratumoral immune signature, and could have an impact in prognosis. We showed that mature dendritic cells density, located in tertiary lymphoid structures, differed according to EGFR and KRAS status. Morever, molecular status of tumors modified the pronostic value of mature dendritics cells and CD8+ T cells. We found a prognostic value of immune environment, represented by dendritic cells and T CD8+ cells, in operated stage III-N2 lung carcinomas treated by neoadjuvant chemotherapy. At last, we demonstrated that chemotherapy is not associated with wide modifications in immune infiltrate, whereas it induced modifications in tumoral cells. All together, these data strongly argue for a close link between tumoral cells and immune environment, which seems to depend on tumoral cell characteristics. This interaction between tumoral cells and immune cells contribute to the prognosis of these tumors. These results show the evidence that combine cytotoxic treatment, like conventional chemotherapy, with immunomodulators, favour a protective anti-tumor immune response