Literatura académica sobre el tema "CDKIs"
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Artículos de revistas sobre el tema "CDKIs"
Campbell, Grace Jean, Emma Langdale Hands y Mathew Van de Pette. "The Role of CDKs and CDKIs in Murine Development". International Journal of Molecular Sciences 21, n.º 15 (28 de julio de 2020): 5343. http://dx.doi.org/10.3390/ijms21155343.
Texto completoGiannone, Gaia, Valentina Tuninetti, Eleonora Ghisoni, Sofia Genta, Giulia Scotto, Gloria Mittica y Giorgio Valabrega. "Role of Cyclin-Dependent Kinase Inhibitors in Endometrial Cancer". International Journal of Molecular Sciences 20, n.º 9 (12 de mayo de 2019): 2353. http://dx.doi.org/10.3390/ijms20092353.
Texto completoPhuong, Lisa, Janki Patel, Nadia Baka, Jessica Goldman, Michael Lyudmer, Stephanie Shamir, Junwen Deng, Alvaro Alvarez Soto y Jesus Del Santo Anampa Mesias. "Effect of cyclin-dependent kinase 4 and 6 inhibitors (CDKIs) on body composition (BC) in patients (pts) with hormone receptor-positive, HER2-negative (HR+/HER2-) metastatic breast cancer (MBC)." Journal of Clinical Oncology 39, n.º 15_suppl (20 de mayo de 2021): e13033-e13033. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e13033.
Texto completoChao, Sheng-Hao, John R. Walker, Sumit K. Chanda, Nathanael S. Gray y Jeremy S. Caldwell. "Identification of Homeodomain Proteins, PBX1 and PREP1, Involved in the Transcription of Murine Leukemia Virus". Molecular and Cellular Biology 23, n.º 3 (1 de febrero de 2003): 831–41. http://dx.doi.org/10.1128/mcb.23.3.831-841.2003.
Texto completoDao, Mo A. y Catherine M. Verfaillie. "STI571 Suppresses Proliferation by Restoring Nuclear Cyclin Dependent Kinase Inhibitors (CDKIs) while STI571+TRAIL Promotes Cell Death by Decreasing Cytoplasmic CDKIs." Blood 104, n.º 11 (16 de noviembre de 2004): 1992. http://dx.doi.org/10.1182/blood.v104.11.1992.1992.
Texto completoAbdelmalak, Mary, Rajanbir Singh, Mohammed Anwer, Pavel Ivanchenko, Amritdeep Randhawa, Myra Ahmed, Anthony W. Ashton, Yanming Du, Xuanmao Jiao y Richard Pestell. "The Renaissance of CDK Inhibitors in Breast Cancer Therapy: An Update on Clinical Trials and Therapy Resistance". Cancers 14, n.º 21 (1 de noviembre de 2022): 5388. http://dx.doi.org/10.3390/cancers14215388.
Texto completoGervaso, Lorenzo, Alberto J. Montero, Xuefei Jia y Alok A. Khorana. "Venous thromboembolism in breast cancer patients receiving cyclin-dependent kinase inhibitors." Journal of Clinical Oncology 37, n.º 15_suppl (20 de mayo de 2019): e18184-e18184. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e18184.
Texto completoZeki, K., I. Morimoto, T. Arao, S. Eto y U. Yamashita. "Interleukin-1alpha regulates G1 cell cycle progression and arrest in thyroid carcinoma cell lines NIM1 and NPA". Journal of Endocrinology 160, n.º 1 (1 de enero de 1999): 67–73. http://dx.doi.org/10.1677/joe.0.1600067.
Texto completoBuckley, S., B. Driscoll, K. D. Anderson y D. Warburton. "Cell cycle in alveolar epithelial type II cells: integration of Matrigel and KGF". American Journal of Physiology-Lung Cellular and Molecular Physiology 273, n.º 3 (1 de septiembre de 1997): L572—L580. http://dx.doi.org/10.1152/ajplung.1997.273.3.l572.
Texto completoBencivenga, Debora, Emanuela Stampone, Angela Vastante, Myassar Barahmeh, Fulvio Della Ragione y Adriana Borriello. "An Unanticipated Modulation of Cyclin-Dependent Kinase Inhibitors: The Role of Long Non-Coding RNAs". Cells 11, n.º 8 (14 de abril de 2022): 1346. http://dx.doi.org/10.3390/cells11081346.
Texto completoTesis sobre el tema "CDKIs"
Henderson, Andrew. "Isosteres of sulfonamide inhibitors of cyclin-dependent kinases (CDKs)". Thesis, University of Newcastle Upon Tyne, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.512187.
Texto completoMarchetti, Francesco. "Structure-activity relationships for alkoxypirimidine inhibitors of cyclin-dependent kinases (CDK’s)". Thesis, University of Newcastle Upon Tyne, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.556141.
Texto completoLolli, Graziano. "Cdks at the interface of cell cycle and and transcription regulation". Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.426389.
Texto completoChiurato, Matteo. "Synthèse de tétrahydropyrido-[isoindolones/isoquinolones/indolizinones] pour l'élaboration d'inhibiteurs de CDks". Orléans, 2007. http://www.theses.fr/2007ORLE2069.
Texto completoDelmas, Christelle. "Modes de régulation de l'inhibiteur de CDKs, p27kip1, par les MAPKsp42/p44". Toulouse 3, 2003. http://www.theses.fr/2003TOU30006.
Texto completoBettayeb, Karima. "Optimisation et caractérisation de nouveaux inhibiteurs pharmacologiques de kinases cycline-dépendantes (CDKs)". Rennes 1, 2008. http://www.theses.fr/2008REN1S025.
Texto completoCyclin-dependent kinases (CDKs) are key regulators of cell division cycle (CDK1, 2, 3, 4, 6, 7), apoptosis (CDK1, 5), and transcription (CDK7, 9). Pharmacological inhibitors of CDKs constitute a new family of potential antitumor agents: ten are under clinical trials, among which roscovitine, was discovered in our laboratory. My thesis is about identification, optimisation and characterization of biochemical and cellular effects of three new kinase inhibitory classes: 7-bromo-indirubins (7BIO), meriolin and new analogs of roscovitine (N&N1 and C&R8). 7BIO induces non-apoptotic cell death through an unknown mechanism (no release of cytochrome C, nor caspase activation). On the other hand, meriolins and second generation roscovitine analogs induce a classical apoptosis due to CDK9 inhibition, thus leading to disappearance of the cell survival factor, Mcl-1. These three classes of chemicals display promising anti-proliferative and antitumor properties
Wołowiec, Dariusz. "Étude des CDKS et des cyclines dans le tissu lymphoïde normal et pathologique". Lyon 1, 1995. http://www.theses.fr/1995LYO1T147.
Texto completoAppleyard, Lindsey Jemma. "Overcoming financial exclusion : Community Development Finance Institutions (CDFIs) and the balancing of financial and social objectives". Thesis, University of Birmingham, 2008. http://etheses.bham.ac.uk//id/eprint/386/.
Texto completoBaïdi, Feriel. "Simplicity and complexity in cell cycle control". Thesis, Rennes 1, 2016. http://www.theses.fr/2016REN1B021.
Texto completoThe cyclin-dependent protein kinases (CDKs) are at the core of cell cycle control. In fission yeast, cell proliferation is regulated by CDK1/Cdc2 in association with the four cyclins Cdc13, Cig1, Cig2 and Puc1 at different stages of the cell cycle. However, this complex endogenous system can be replaced by a minimal module consisting of a fusion between Cdc2 and Cdc13 in the absence of G1/S cyclins. Surprisingly, this minimal CDK network drives the entire cell cycle in a wild type manner. Since a number of aspects of cell cycle control in fission yeast appear to be dispensable, we asked why similarly simplified circuits were not selected over the complex endogenous network during evolution. This led us to investigate the limits of such minimal systems, in particular when challenged by different stresses. Unexpectedly, we uncovered that simplification of the CDK network confers resistance to replication stress. We showed that this phenotype is independent from the CDK inhibitor Rum1 and the existing checkpoint pathways. It solely relies on operating the entire cell cycle with a single cyclin, Cdc13, and is associated with reduced genome instability when replication is challenged. However, it is not the consequence of changes in replication organisation along the chromosomes. Our data suggest that G1/S cyclin-associated Cdc2 activity may represent an alternative as yet unknown means of modulating cellular response to DNA stress. We also took advantage of a derivative of the minimal cell cycle network, in which Cdc2 is made sensitive to specific chemical inhibition. As a result, CDK activity can be externally modulated and cell cycle phases can be precisely controlled. Using this system, we re-visited the interplay between CDK and periodic transcription, a highly conserved process that is critical for proper cell proliferation. In contrast with previous studies in budding yeast, we demonstrate that periodic transcription in fission yeast is not independent from cell cycle progression. On the contrary, our work reveals that cell cycle transcriptional oscillations rely on quantitative changes in CDK activity levels. We therefore propose a new model, in which cell cycle progression and periodic transcription are intimately coupled through their common dependency on a unique input, namely CDK activity levels
Tikad, Abdellatif. "Développement de nouvelles pyrido[3,2-d]pyrimidines polyfonctionnalisées : application à la synthèse d’inhibiteurs de CDKs". Orléans, 2008. http://www.theses.fr/2008ORLE2079.
Texto completoLibros sobre el tema "CDKIs"
Lehr, Margaret B. Best practices for CDFIs: Key principles for performance. Philadelphia, PA (924 Cherry St., Second Fl, Philadelphia 19107): National Community Capital, 1998.
Buscar texto completoTreasury, Great Britain, ed. Mapping of credit unions and community development finance institutions (CDFIs). London: HMSO, 2005.
Buscar texto completoChapman, Deborah Lynne. Identification of murine B-type cyclins expressed during gametogenesis and examination of their potential functions in association with CDC2 and CDKS. [New York]: [Columbia University], 1993.
Buscar texto completoImmergluck, Daniel. CRA & CDFIs: The Community Reinvestment Act and community development financial institutions : qualified investments, community development lending, and lessons from the new CRA performance evaluations. Chicago (407 S. Dearborn, Chicago 60605): Woodstock Institute, 1998.
Buscar texto completoCommunity development financial institutions (CDFIs): Their unique role and challenges serving lower-income, underserved, and minority communities : hearing before the Committee on Financial Services, U.S. House of Representatives, One Hundred Eleventh Congress, second session, March 9, 2010. Washington: U.S. G.P.O., 2010.
Buscar texto completoUnited States. National Aeronautics and Space Administration, ed. Crustal Dynamics Data Information System: CDDIS. [Washington, DC: National Aeronautics and Space Administration, 1993.
Buscar texto completoTansey, Charles, Michael Swack y Michael Tansey. Capital Markets, Cdfis, and Organizational Credit Risk. Lulu Press, Inc., 2010.
Buscar texto completoMacarthur Communicative Development Inventories (Cdis): Words And Sentences. Brookes Publishing Company, 2003.
Buscar texto completoStaff, International Monetary Fund. Coordinated Direct Investment Survey Guide 2015 (CDIS 2015). International Monetary Fund, 2015.
Buscar texto completoMacarthur Communicative Development Inventories (Cdis): Words And Gestures. Brookes Publishing Company, 2003.
Buscar texto completoCapítulos de libros sobre el tema "CDKIs"
Solomon, M. J. y P. Kaldis. "Regulation of CDKs by phosphorylation". En Results and Problems in Cell Differentiation, 79–109. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-540-69686-5_4.
Texto completoMir, Manzoor Ahmad y Abrar Yousuf Mir. "Breast Tumor Microenvironment and CDKs". En Therapeutic potential of Cell Cycle Kinases in Breast Cancer, 149–74. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-8911-7_7.
Texto completoGupta, Anand, Anita Kumari, Boris Kundu y Isha Agarwal. "CDIS: Circle Density Based Iris Segmentation". En Communications in Computer and Information Science, 295–306. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-03547-0_28.
Texto completoMir, Manzoor Ahmad y Burhan Ul Haq. "Therapeutic Implications of CDKs in Breast Cancer". En Therapeutic potential of Cell Cycle Kinases in Breast Cancer, 233–52. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-8911-7_11.
Texto completoMir, Manzoor Ahmad y Umar Y. Mir. "Targeting CDKs with Other Chemotherapeutic Drugs: A Combinatorial Approach". En Therapeutic potential of Cell Cycle Kinases in Breast Cancer, 269–89. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-8911-7_13.
Texto completoNoll, Carey E. "Data archiving and distribution for the Crustal Dynamics Project: The CDDIS". En Contributions of Space Geodesy to Geodynamics: Technology, 27–45. Washington, D. C.: American Geophysical Union, 1993. http://dx.doi.org/10.1029/gd025p0027.
Texto completoPinhero, Reena y Krassimir Yankulov. "Expression and Purification of Recombinant CDKs: CDK7, CDK8, and CDK9". En Methods in Molecular Biology, 13–28. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-2926-9_3.
Texto completoWilliams, Paul D., Kevin P. Anchor, John L. Bebo, Gregg H. Gunsch y Gary D. Lamont. "CDIS: Towards a Computer Immune System for Detecting Network Intrusions". En Lecture Notes in Computer Science, 117–33. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/3-540-45474-8_8.
Texto completoMcClendon, A. Kathleen, Jeffry L. Dean y Erik S. Knudsen. "Regulation of Pre-RC Assembly: A Complex Symphony Orchestrated by CDKs". En Cell Cycle Deregulation in Cancer, 43–55. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-1770-6_3.
Texto completoGallastegui, Edurne y Oriol Bachs. "Expression and Purification of Recombinant Cyclins and CDKs for Activity Evaluation". En Methods in Molecular Biology, 9–12. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-2926-9_2.
Texto completoActas de conferencias sobre el tema "CDKIs"
Chen, Da-Ming, Y. F. Xu y W. D. Zhu. "Non-Model-Based Multiple Damage Identification of Beams Under Spatially Dense Vibration Measurement". En ASME 2017 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/imece2017-72430.
Texto completoSaxena, Bhawanjali, Kumud Pant, Bhasker Pant y K. R. Pardasani. "Dipeptide based SVM model for prediction of CDKs and cyclins". En 2nd International Conference on Computer and Automation Engineering (ICCAE 2010). IEEE, 2010. http://dx.doi.org/10.1109/iccae.2010.5451233.
Texto completoSaxena, Bhawanjali, Kumud Pant, Bhasker Pant y Neeru Adlakha. "Hybrid based SVM model for prediction of CDKs and cyclins". En 2nd International Conference on Computer and Automation Engineering (ICCAE 2010). IEEE, 2010. http://dx.doi.org/10.1109/iccae.2010.5451262.
Texto completoZhao, Tianna, Riccardo Serra, Michelle Guo, Peter C. Burger, Lisa M. Rooper, Betty Tyler, Christine L. Hann y Gary L. Gallia. "CDKS Blockade Enhances In Vivo Efficacy of EGFR Inhibition in Chordomas". En Special Virtual Symposium of the North American Skull Base Society. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1725264.
Texto completoStevens, K. J., K. Lichti, I. A. Minchington, N. Janke-Gilman, T. Mactutis, D. Rook y P. Bondurant. "Conductor Damage Inspection System for overhead ACSR power cables CDIS on ACSR". En 2013 Seventh International Conference on Sensing Technology (ICST). IEEE, 2013. http://dx.doi.org/10.1109/icsenst.2013.6727780.
Texto completoRajput, Sandeep, Zhanfang Guo y Cynthia Ma. "Abstract 3097: CDKs inhibitor: potential monotherapy for treatment of triple-negative breast cancer". En Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-3097.
Texto completoLu, Shuyan, Wenyue Hu, Tae Sung, Brad Hirakawa, Marina Amaro y Bart Jessen. "Abstract 99: Phenotypic characterization of knockdown of CDKs in the intestinal epithelial cells". En Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-99.
Texto completoTadesse, Solomon, Laychiluh Bantie, Khamis Tomusange, Saiful Islam, Muhammed H. Rahaman, Benjamin Noll, Frankie Lam, Mingfeng Yu y Shudong Wang. "Abstract 2353: CDKI-15, a novel and highly selective CDK4/6 inhibitor: discovery,in vitroandin vivoanticancer efficacy". En Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-2353.
Texto completoRieß, C., CF Classen y C. Maletzki. "CDKs as target structures for cancer therapy – an in vitro analysis on patient-derived glioblastoma cell lines". En 28th Annual Meeting of the working group “Experimental Neuro-Oncology”. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1696331.
Texto completoShapiro, G. "Abstract MS1-1: Beyond CDK 4/6: Targeting additional cell cycle and transcriptional CDKs in breast cancer". En Abstracts: Thirty-Eighth Annual CTRC-AACR San Antonio Breast Cancer Symposium; December 8-12, 2015; San Antonio, TX. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.sabcs15-ms1-1.
Texto completoInformes sobre el tema "CDKIs"
Tansey, Charles, Michael Swack, Michael Tansey y Vicky Stein. Capital markets, CDFIs, and organizational credit risk. University of New Hampshire Libraries, 2010. http://dx.doi.org/10.34051/p/2020.123.
Texto completoJayson Wharton, Edward Seabury, Gus Caffrey y Phili. Summary Report: INL CDCIS Cask Scanner Testing at. Office of Scientific and Technical Information (OSTI), abril de 2013. http://dx.doi.org/10.2172/1087695.
Texto completoSwack, Michael, Eric Hangen y Jack Northrup. CDFIs Stepping into the Breach: An Impact Evaluation—Summary Report. University of New Hampshire Libraries, 2015. http://dx.doi.org/10.34051/p/2020.228.
Texto completoNorthrup, Jack, Eric Hangen y Michael Swack. CDFIs and Online Business Lending: A Review of Recent Progress, Challenges, and Opportunities. University of New Hampshire Libraries, 2016. http://dx.doi.org/10.34051/p/2020.276.
Texto completoWilliams, Teshanee, Jamie McCall, Natalie Prochaska y Tamra Thetford. How Community Development Financial Institutions (CDFIs) are shaped by Funders through Data Collection, Impact Measurement, and Evaluation. Carolina Small Business Development Fund, noviembre de 2022. http://dx.doi.org/10.46712/cdfi.evaluation.pressures.
Texto completoTansey, Charles y Michael Swack. The Potential Role For CDFIs in the Opportunity Zones of the Investing in Opportunities Act (IIOA). University of New Hampshire Libraries, 2019. http://dx.doi.org/10.34051/p/2020.350.
Texto completoMcCall, Jamie y Emily Stallings. Assessing Public, Private, and Philanthropic Support for CDFIs: Data on Contributing Operating Revenues and Measures of Efficiency. Carolina Small Business Development Fund, diciembre de 2020. http://dx.doi.org/10.46712/cdfi.revenue.sources.
Texto completoHangen, Eric y Michael E. Hangen. CDFIs Can Make the SBA PPP Loan Program Work for Smaller, Minority-Owned, and Women-Owned, Small Businesses. University of New Hampshire Libraries, 2020. http://dx.doi.org/10.34051/p/2020.386.
Texto completoMcCall, Jamie, Nora Anzawi, Miles Zeller y James Onorevole. Growth, Equity, and Individual Welfare: A Theoretical Framework for “Moving the Needle” on CDFI Impact Evaluation. Carolina Small Business Development Fund and AltCap, enero de 2023. http://dx.doi.org/10.46712/evaluation.frameworks.
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